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https://www.readbyqxmd.com/read/28843139/sources-distribution-bioavailability-toxicity-and-risk-assessment-of-heavy-metal-loid-s-in-complementary-medicines
#1
REVIEW
Shiv Bolan, Anitha Kunhikrishnan, Balaji Seshadri, Girish Choppala, Ravi Naidu, Nanthi S Bolan, Yong Sik Ok, Ming Zhang, Chun-Guang Li, Feng Li, Barry Noller, Mary Beth Kirkham
The last few decades have seen the rise of alternative medical approaches including the use of herbal supplements, natural products, and traditional medicines, which are collectively known as 'Complementary medicines'. However, there are increasing concerns on the safety and health benefits of these medicines. One of the main hazards with the use of complementary medicines is the presence of heavy metal(loid)s such as arsenic (As), cadmium (Cd), lead (Pb), and mercury (Hg). This review deals with the characteristics of complementary medicines in terms of heavy metal(loid)s sources, distribution, bioavailability, toxicity, and human risk assessment...
August 23, 2017: Environment International
https://www.readbyqxmd.com/read/28723722/complementary-and-alternative-medicine-use-and-symptom-burden-in-women-undergoing-chemotherapy-for-breast-cancer-in-malaysia
#2
Ping Lei Chui, Khatijah Lim Abdullah, Li Ping Wong, Nur Aishah Taib
BACKGROUND: Complementary and alternative medicine (CAM) is commonly used for cancer- and chemotherapy-related symptoms. Nurses are likely to encounter many CAM users in their practice. OBJECTIVE: The aims of this study were to assess CAM use and examine the symptom burden of CAM and non-CAM users among patients with breast cancer who are undergoing chemotherapy. METHODS: A CAM use questionnaire and the Side-Effect Burden Scale were administered to 546 patients...
July 14, 2017: Cancer Nursing
https://www.readbyqxmd.com/read/28401813/epistemological-challenges-in-contemporary-western-healthcare-systems-exemplified-by-people-s-widespread-use-of-complementary-and-alternative-medicine
#3
Anita Salamonsen, Rolf Ahlzén
Modern Western public healthcare systems offer predominantly publicly subsidized healthcare traditionally based on biomedicine as the most important basis to cure persons who suffer from disorders of somatic or psychiatric nature. To which extent this epistemological position is suitable for this purpose is under scientific debate and challenged by some people's personal understandings of health and illness, their individual illness experiences and their decision-making. Current studies show decreasing levels of patient trust in Western public healthcare and a widespread patient-initiated use of complementary and alternative medicine which is often linked to unmet patient-defined healthcare needs...
January 1, 2017: Health (London)
https://www.readbyqxmd.com/read/28364873/broadening-our-perspectives-on-complementary-and-alternative-medicine-for-menopause-a-narrative-review
#4
REVIEW
Dunia Tonob, Melissa K Melby
Complementary and alternative medicine (CAM) is widely used for menopause, although not all women disclose use to their healthcare providers. This narrative review aims to expand providers' understanding of cross-cultural approaches to treating and managing menopause by providing an overarching framework and perspective on CAM treatments. Increased provider understanding and awareness may improve not only provider-patient communication but also effectiveness of treatments. The distinction between illness (what patients suffer) and disease (what physicians treat) highlights the gap between what patients seek and doctors provide, and may help clarify why many women seek CAM at menopause...
May 2017: Maturitas
https://www.readbyqxmd.com/read/28325144/therapeutic-potential-and-outlook-of-alternative-medicine-for-osteoporosis
#5
Tao Wang, Qian Liu, William Tjhioe, Jinmin Zhao, Aiping Lu, Ge Zhang, Ren Xiang Tan, Mengyu Zhou, Jiake Xu, Hao Tian Feng
Osteoporosis, a bone disease resulting in the loss of bone density and microstructure quality, is often associated with fragility fractures, and the latter imposes a great burden on the patient and society. Although there are several different treatments available for osteoporosis such as hormone replacement therapy, bisphosphonates, Denosumab, and parathyroid hormone, some concerns have been raised regarding the inherent side effects of their long term use. It would be of great relevance to search for alternative natural compounds, which could complementarily overcome the limitations of the currently available therapy...
2017: Current Drug Targets
https://www.readbyqxmd.com/read/28216951/a-qualitative-insight-on-complementary-and-alternative-medicines-used-by-hypertensive-patients
#6
Inas Rifaat Ibrahim, Mohamed Azmi Hassali, Fahad Saleem, Haydar F Al Tukmagi
BACKGROUND: The self-treatment with complementary and alternative medicines (CAMs) in chronic diseases is portraying an expanding trend worldwide. Yet, little is known concerning patients' motives to use CAM in the control of blood pressure. OBJECTIVE: This study aims to explore the self-use of CAM in the management of hypertension and explore patients' attitudes, perceived benefits, and disclosure to the physician. MATERIALS AND METHODS: A qualitative technique was adopted and face-to-face interviews, using a validated interview guide, were carried out among twenty hypertensive patients...
October 2016: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/28208654/a-protein-isolate-from-moringa-oleifera-leaves-has-hypoglycemic-and-antioxidant-effects-in-alloxan-induced-diabetic-mice
#7
Paulo C Paula, Daniele O B Sousa, Jose T A Oliveira, Ana F U Carvalho, Bella G T Alves, Mirella L Pereira, Davi F Farias, Martonio P Viana, Flavia A Santos, Talita C Morais, Ilka M Vasconcelos
Moringa oleifera has been used in traditional medicine to treat diabetes. However, few studies have been conducted to relate its antidiabetic properties to proteins. In this study, a leaf protein isolate was obtained from M. oleifera leaves, named Mo-LPI, and the hypoglycemic and antioxidant effects on alloxan-induced diabetic mice were assessed. Mo-LPI was obtained by aqueous extraction, ammonium sulphate precipitation and dialysis. The electrophoresis profile and proteolytic hydrolysis confirmed its protein nature...
February 11, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28075551/cucurbit-n-uril-based-microcapsules-self-assembled-within-microfluidic-droplets-a-versatile-approach-for-supramolecular-architectures-and-materials
#8
Ji Liu, Yang Lan, Ziyi Yu, Cindy S Y Tan, Richard M Parker, Chris Abell, Oren A Scherman
Microencapsulation is a fundamental concept behind a wide range of daily applications ranging from paints, adhesives, and pesticides to targeted drug delivery, transport of vaccines, and self-healing concretes. The beauty of microfluidics to generate microcapsules arises from the capability of fabricating monodisperse and micrometer-scale droplets, which can lead to microcapsules/particles with fine-tuned control over size, shape, and hierarchical structure, as well as high reproducibility, efficient material usage, and high-throughput manipulation...
February 21, 2017: Accounts of Chemical Research
https://www.readbyqxmd.com/read/27933645/aflatoxin-biomarkers-in-hair-may-facilitate-long-term-exposure-studies
#9
Innocent Mupunga, Christo D Izaaks, Leshweni J Shai, David R Katerere
Aflatoxins are highly toxic fungal metabolites produced by some members of the Aspergillus species. They are low molecular weight lipophilic compounds that are easily absorbed from the gastrointestinal tract. They contaminate most staple foods, including maize, peanuts, peanut butter and sorghum mainly in the tropics where hot and humid conditions promote fungal growth. Absorbed aflatoxins are metabolized by the cytochrome P450 enzyme system in the liver into toxic metabolites. Aflatoxin B (AFB)1 is the most toxic, carcinogenic and mutagenic naturally occurring toxin...
April 2017: Journal of Applied Toxicology: JAT
https://www.readbyqxmd.com/read/27758689/mechanisms-of-anorexia-cancer-cachexia-syndrome-and-potential-benefits-of-traditional-medicine-and-natural-herbs
#10
REVIEW
Cong Ming-Hua, Zou Bao-Hua, Yu Lei
Anorexia cancer cachexia syndrome is prevalent in advanced cancer patients, which is featured by anorexia, decreased dietary intake, body weight loss (skeletal muscle mass loss), and is unable to be reversed by routine nutritional support therapy. Up to now, the main mechanisms involved in cancer cachexia include excessive systemic inflammation, which is represented by increased plasma levels of IL-1, IL-6, TNF-alpha, tumor-induced factors, such as PIF and LMF. These factors eventually act on orexigenic and anorexigenicneurons located in the hypothalamus or protein and lipid metabolism of peripheral tissues, which lead to anorexia, decreased dietary intake, enhanced basic metabolism rate and hypercatabolism...
2016: Current Pharmaceutical Biotechnology
https://www.readbyqxmd.com/read/27663925/acupuncture-as-a-complementary-method-of-traditional-psoriasis-treatment-myth-or-reality
#11
Darija Mahović, Fanika Mrsić
Dear Editor, the practitioners of traditional Chinese medicine described psoriasis some 2000 years ago (1). Psoriasis vulgaris is a common, chronic inflammatory skin disease whose worldwide prevalence ranges from 0.1-3% (2,3). Understanding the role of the immune system in psoriasis and the interplay between the innate and adaptive immune system has helped to manage this complex disease, which affects patients far beyond the skin changes themselves (2). In addition to the usual and widely accepted methods of treatment of psoriasis, including topical therapies, phototherapy, and conventional and biological systemic therapies, data can be found in the literature that suggest a favorable effect of acupuncture on the course of psoriasis (4,5)...
August 2016: Acta Dermatovenerologica Croatica: ADC
https://www.readbyqxmd.com/read/27624970/fecal-metabolome-of-the-hadza-hunter-gatherers-a-host-microbiome-integrative-view
#12
Silvia Turroni, Jessica Fiori, Simone Rampelli, Stephanie L Schnorr, Clarissa Consolandi, Monica Barone, Elena Biagi, Flaminia Fanelli, Marco Mezzullo, Alyssa N Crittenden, Amanda G Henry, Patrizia Brigidi, Marco Candela
The recent characterization of the gut microbiome of traditional rural and foraging societies allowed us to appreciate the essential co-adaptive role of the microbiome in complementing our physiology, opening up significant questions on how the microbiota changes that have occurred in industrialized urban populations may have altered the microbiota-host co-metabolic network, contributing to the growing list of Western diseases. Here, we applied a targeted metabolomics approach to profile the fecal metabolome of the Hadza of Tanzania, one of the world's few remaining foraging populations, and compared them to the profiles of urban living Italians, as representative of people in the post-industrialized West...
September 14, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27610179/the-use-of-complementary-and-alternative-medicine-in-children-with-common-neurologic-diseases
#13
REVIEW
Gyu-Min Yeon, Sang Ook Nam
Complementary and alternative medicine (CAM) is a phrase used to describe additional health care methods such as mind/body practices and natural products not regarded as treatments by conventional medicine. The use of CAM in children with common neurologic diseases is more frequent than its use in healthy children (24%-78% vs. 12%). However, less than half of patients report such use to their physicians. The preferred modalities of CAM vary in different countries due to their different cultures and traditions...
August 2016: Korean Journal of Pediatrics
https://www.readbyqxmd.com/read/27580857/complementary-and-alternative-medicine-s-occupational-closure-in-portuguese-healthcare-contradictions-and-challenges
#14
Joana Almeida
This article analyses strategies of closure recently enacted by complementary and alternative medicine practitioners in order to achieve occupational control over work domains in healthcare, taking Portugal as an example. A combination of the neo-Weberian occupational closure theory of the professions and Abbott's jurisdictional vacancy theory is proposed as the framework for analysis. Acupuncture and homeopathy will be presented as case studies. Data are derived from in-depth interviews with 10 traditional acupuncturists and 10 traditional homeopaths...
September 2016: Health (London)
https://www.readbyqxmd.com/read/27515029/therapies-for-parkinson-s-diseases-alternatives-to-current-pharmacological-interventions
#15
REVIEW
Song Li, Jie Dong, Cheng Cheng, Weidong Le
Parkinson's disease (PD) is the second most common neurodegenerative disorder caused by the selective and progressive loss of dopaminergic neurons in the substantia nigra pars compacta. Although PD has been heavily researched, the precise etiology and pathogenesis for PD are still inconclusive. Consequently, current pharmacological treatments for PD are largely symptomatic rather than preventive and there is still no cure for this disease nowadays. Moreover, nonmotor symptoms caused by intrinsic PD pathology or side effects induced by currently used pharmacological interventions are gaining increasing attention and urgently need to be treated due to their influence on quality of life...
November 2016: Journal of Neural Transmission
https://www.readbyqxmd.com/read/27452083/proteomics-of-hot-wet-and-cold-dry-temperaments-proposed-in-iranian-traditional-medicine-a-network-based-study
#16
Hassan Rezadoost, Mehrdad Karimi, Mohieddin Jafari
Lack of molecular biology evidence has led clinical success of alternative and complementary medicine (CAM) to be marginalized. In turn, a large portion of life Science researchers could not communicate and help to develop therapeutic potential laid in these therapeutic approaches. In this study, we began to quantify descriptive classification theory in one of the CAM branches i.e. Iranian traditional medicine (ITM). Using proteomic tools and network analysis, the expressed proteins and their relationships were studied in mitochondrial lysate isolated from PBMCs from two different temperaments i...
2016: Scientific Reports
https://www.readbyqxmd.com/read/27436344/specialization-of-a-polyphenism-switch-gene-following-serial-duplications-in-pristionchus-nematodes
#17
Erik J Ragsdale, Nicholas A Ivers
Polyphenism is an extreme manifestation of developmental plasticity, requiring distinct developmental programs and the addition of a switch mechanism. Because the genetic basis of polyphenism switches has only begun to be understood, how their mechanisms arise is unclear. In the nematode Pristionchus pacificus, which has a mouthpart polyphenism specialized for alternative diets, a gene (eud-1) executing the polyphenism switch was recently identified as the product of lineage-specific duplications. Here, we infer the role of gene duplications in producing a switch gene...
September 2016: Evolution; International Journal of Organic Evolution
https://www.readbyqxmd.com/read/27417522/a-mechanistic-review-on-medicinal-plants-used-for-rheumatoid-arthritis-in-traditional-persian-medicine
#18
REVIEW
Mohammad Hosein Farzaei, Fatemeh Farzaei, Mohammad Abdollahi, Zahra Abbasabadi, Amir Hossein Abdolghaffari, Bahman Mehraban
OBJECTIVES: Rheumatoid arthritis (RA) is a chronic, inflammatory, autoimmune disease, which affects synovial tissue in multiple joints. Although conventional treatments of RA commonly alleviate the symptoms, high incidence of adverse reactions leads to research tendency towards complementary and alternative medicine. As various medicinal plants are traditionally used for the management of symptomatologies associated with RA in Persian medicine, we reviewed medicinal literature to confirm their efficacy in the management of RA...
October 2016: Journal of Pharmacy and Pharmacology
https://www.readbyqxmd.com/read/27350107/advance-in-studies-on-traditional-chinese-medicines-to-treat-infection-with-the-hepatitis-b-virus-and-hepatitis-c-virus
#19
REVIEW
Jufeng Xia, Yoshinori Inagaki, Peipei Song, Tatsuo Sawakami, Norihiro Kokudo, Kiyoshi Hasegawa, Yoshihiro Sakamoto, Wei Tang
Traditional Chinese medicine (TCM), as a type of complementary and alternative medicine (CAM), is a sophisticated and time-honored form of healthcare in China. Many TCMs are widely used to treat hepatitis B and hepatitis C in countries like China, Japan, and South Korea. Since conventional clinical preparations like interferon-α cause obvious dose-dependent adverse reactions and drug resistance, TCMs and related bioactive compounds have garnered increasing attention from physicians and medical researchers...
November 15, 2016: Bioscience Trends
https://www.readbyqxmd.com/read/27350006/croton-megalobotrys-m%C3%A3-ll-arg-and-vitex-doniana-sweet-traditional-medicinal-plants-in-a-three-step-treatment-regimen-that-inhibit-in-vitro-replication-of-hiv-1
#20
Ian Tietjen, Teresia Gatonye, Barbara N Ngwenya, Amos Namushe, Sundana Simonambanga, Mbaki Muzila, Philip Mwimanzi, Jianbo Xiao, David Fedida, Zabrina L Brumme, Mark A Brockman, Kerstin Andrae-Marobela
ETHNOPHARMACOLOGICAL RELEVANCE: Human Immunodeficiency Virus (HIV) strains resistant to licensed anti-retroviral drugs (ARVs) continue to emerge. On the African continent, uneven access to ARVs combined with occurrence of side-effects after prolonged ARV therapy have led to searches for traditional medicines as alternative or complementary remedies to conventional HIV/AIDS management. AIM OF THE STUDY: Here we characterize a specific three-step traditional HIV/AIDS treatment regimen consisting of Cassia sieberiana root, Vitex doniana root, and Croton megalobotrys bark by combining qualitative interviews of traditional medical knowledge users in Botswana with in vitro HIV replication studies...
September 15, 2016: Journal of Ethnopharmacology
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