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https://www.readbyqxmd.com/read/29676809/prevalence-of-maternal-birth-trauma-in-nepali-women
#1
Friyan Turel, Delena Caagbay, Hans Peter Dietz
OBJECTIVES: Pelvic organ prolapse is very common among women in Nepal, especially uterine prolapse. This would suggest a high rate of levator trauma, which is a strong predictor of such prolapse in the Western world. Hence, we decided to study the prevalence of maternal birth trauma in Nepali women. METHODS: In November 2016, we offered an interview, clinical examination, and 4-dimensional translabial sonography to women attending a gynecology clinic. Of 129 women seen, 5 were excluded due to previous pelvic surgery...
April 20, 2018: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/29676728/detection-of-candida-species-in-pregnant-chinese-women-with-a-molecular-beacon-method
#2
Yanhong Zhai, Jing Liu, Li Zhou, Tongzhen Ji, Lingxin Meng, Yang Gao, Ran Liu, Xiao Wang, Lin Li, Binghuai Lu, Zheng Cao
PURPOSE: Candida pathogens are commonly found in women and can cause vulvovaginal candidiasis (VVC), whose infection rate is further increased during pregnancy. We aimed to study the Candida prevalence and strain distribution in pregnant Chinese women with a molecular beacon assay. METHODOLOGY: From March 2016 to February 2017, a total of 993 pregnant women attending routine antenatal visits at the Beijing Obstetrics and Gynecology Hospital were enrolled. For Candida detection and identification, a unique molecular beacon assay was presented and compared with a traditional phenotypic method...
April 20, 2018: Journal of Medical Microbiology
https://www.readbyqxmd.com/read/29675249/ultrasensitive-and-specific-fluorescence-detection-of-a-cancer-biomarker-via-nanomolar-binding-to-a-guanidinium-modified-calixarene
#3
Zhe Zheng, Wen-Chao Geng, Jie Gao, Yu-Ying Wang, Hongwei Sun, Dong-Sheng Guo
We designed a water-soluble guanidinium-modified calix[5]arene to target lysophosphatidic acid (LPA), an ideal biomarker for early diagnosis of ovarian and other gynecologic cancers, achieving binding on the nanomolar level. An indicator displacement assay, coupled with differential sensing, enabled ultrasensitive and specific detection of LPA. Moreover, we show that using a calibration line, the LPA concentration in untreated serum can be quantified in the biologically relevant low μM range with a detection limit of 1...
February 28, 2018: Chemical Science
https://www.readbyqxmd.com/read/29673665/diminished-ovarian-reserve-in-patients-with-psoriasis
#4
Burcu Tuğrul Ayanoğlu, Elif Didem Özdemir, Onur Türkoğlu, Aslıhan Alhan
OBJECTIVE: Psoriasis is a multi-systemic chronic inflammatory skin disease. Previous data suggests that women with some chronic inflammatory diseases have diminished ovarian reserve. This study explores ovarian reserve in patients with psoriasis. MATERIALS AND METHODS: We prospectively analyzed 14 female patients with psoriasis and 35 healthy age and body mass index matched controls. An interview explored demographic characteristics, obstetrical history and menstrual characteristics...
April 2018: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29673657/outstanding-female-cancer-research-paper-awards-of-the-taiwanese-association-of-obstetrics-and-gynecology
#5
EDITORIAL
Peng-Hui Wang, Chih-Ping Chen, Tsung-Cheng Kuo
No abstract text is available yet for this article.
April 2018: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29673656/outstanding-research-paper-awards-of-the-2017-taiwanese-journal-of-obstetrics-and-gynecology
#6
EDITORIAL
Peng-Hui Wang, Chih-Ping Chen, Tsung-Cheng Kuo
No abstract text is available yet for this article.
April 2018: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29673570/pregnancy-and-parental-leave-among-obstetrics-and-gynecology-residents-results-of-a-nationwide-survey-of-program-directors
#7
Eduardo Hariton, Benjamin Matthews, Abigail Burns, Chitra Akileswaran, Lori R Berkowitz
INTRODUCTION: The health and economic benefits of paid parental leave have been well documented. In 2016, the American College of Obstetrics and Gynecology (ACOG) released a policy statement on recommended parental leave for trainees, yet, data on adoption of said guidelines is nonexistent and published data on parental leave policies in Ob-Gyn is outdated. The objective of our study is to understand existing parental leave policies in Ob-Gyn training programs and to evaluate program director opinions on these policies and on parenting in residency...
April 16, 2018: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29672447/effects-of-human-papillomavirus-awareness-and-knowledge-on-psychological-state-of-women-referred-to-cervical-cancer-screening
#8
Ljiljana Markovic-Denic, Olivera Djuric, Natasa Maksimovic, Svetlana Popovac, Vesna Kesic
OBJECTIVE: The aim of the study was to assess the impact of human papillomavirus (HPV) awareness and knowledge on physiological state and quality of life of women referred to colposcopy and/or HPV testing. MATERIALS AND METHODS: A cross-sectional study was carried out at University Hospital, Belgrade, Serbia. The women with abnormal Pap test results obtained at the primary care centers requiring colposcopy and/or HPV testing were included. Before gynecological examination, participants filled the questionnaire on demographic characteristics, gynecological history, questionnaire for the evaluation of HPV awareness and HPV knowledge level, a set of self-report questionnaires assessing the anxiety level, quality of life, and concern about the smear and colposcopy results and perceived risk of developing cervical cancer...
April 19, 2018: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/29671553/cervical-cancer-screening
#9
Caitlyn M Rerucha, Rebecca J Caro, Vernon L Wheeler
Screening in women has decreased the incidence and mortality of cervical cancer. Precancerous cervical lesions (cervical intraepithelial neoplasias) and cervical carcinomas are strongly associated with sexually-transmitted high-risk human papillomavirus (HPV) infection, which causes more than 99% of cervical cancers. Screening methods include cytology (Papanicolaou test) and HPV testing, alone or in combination. The American Academy of Family Physicians and the U.S. Preventive Services Task Force recommend starting screening in immunocompetent, asymptomatic women at 21 years of age...
April 1, 2018: American Family Physician
https://www.readbyqxmd.com/read/29671223/laparoscopic-paraaortic-surgical-staging-in-locally-advanced-cervical-cancer-a-single-center-experience
#10
D Vázquez-Vicente, B Fernández Del Bas, J García Villayzán, H A Di Fiore, J Luna Tirado, V Casado Echarren, J García-Foncillas, J Plaza Arranz, L Chiva
BACKGROUND: One aim of this study was to assess the efficacy and safety of laparoscopic paraaortic lymphadenectomy for paraaortic lymph node staging in locally advanced cervical carcinoma. The second aim was to identify prognostic factors in the evolution of this disease and to evaluate how the results of the surgery modify the oncological treatment of patients. MATERIALS AND METHODS: We analyzed 59 patients diagnosed with locally advanced cervical cancer International Federation of Gynecology and Obstetrics stage IB2-IVA who underwent laparoscopic paraaortic lymphadenectomy at our hospital between 2009 and 2015...
April 18, 2018: Clinical & Translational Oncology
https://www.readbyqxmd.com/read/29670783/autoamputation-of-the-appendix-in-a-chronic-adnexal-abscess
#11
C Michele Markey, Lauren E Vestal
Autoamputation of the appendix has rarely been described in the literature. We present a case of a pelvic mass, thought to be a dermoid cyst based on preoperative imaging. After surgical removal and pathological examination, the mass was found to be a chronic pelvic abscess containing the right adnexa as well as an autoamputated vermiform appendix. Differentiating between gynecologic and gastrointestinal disease preoperatively can be difficult and often a definitive diagnosis cannot be made until surgical exploration and pathological review...
2018: Case Reports in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29670527/comparative-metabolomics-analysis-of-cervicitis-in-human-patients-and-a-phenol-mucilage-induced-rat-model-using-liquid-chromatography-tandem-mass-spectrometry
#12
Xiaoyong Zhang, Junmao Li, Bin Xie, Bei Wu, Shuangxia Lei, Yun Yao, Mingzhen He, Hui Ouyang, Yulin Feng, Wen Xu, Shilin Yang
Cervicitis is an exceedingly common gynecological disorder that puts women at high risk of sexually transmitted infections and induces a series of reproductive system diseases. This condition also has a significant impact on quality of life and is commonly misdiagnosed in clinical practice due to its complicated pathogenesis. In the present study, we performed non-targeted plasma metabolomics analysis of cervicitis in both plasma samples obtained from human patients and plasma samples from a phenol mucilage induced rat model of cervicitis, using ultra-performance liquid chromatography coupled to quadrupole time-of-flight tandem mass spectrometry...
2018: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/29670473/determination-of-the-reference-values-of-the-tumor-marker-he4-in-female-population-of-canton-sarajevo
#13
Lejla Hasanbegovic, Nedeljka Sljivo
Introduction: Ovarian cancer has the highest mortality rate of all gynecological tumors and represent fifth leading cause of cancer death in women, due to the absence of early symptoms of the disease and the lack of screening tests. A new HE4 ovarian cancer biomarker was found in various studies, with different populations having quite different sensitivity and specificity values as well as reference values. The tumor marker HE4 is a useful marker for ovarian cancer detection with only minimal expression in normal ovarian tissue...
March 2018: Materia Socio-medica
https://www.readbyqxmd.com/read/29670400/-anln-functions-as-a-key-candidate-gene-in-cervical-cancer-as-determined-by-integrated-bioinformatic-analysis
#14
Leilei Xia, Xiaoling Su, Jizi Shen, Qi Meng, Jiuqiong Yan, Caihong Zhang, Yu Chen, Han Wang, Mingjuan Xu
Background: Cervical cancer, one of the leading causes of female deaths, remains a top cause of mortality in gynecologic oncology and tends to affect younger individuals. However, the pathogenesis of cervical cancer is still far from clear. Given the high incidence and mortality of cervical cancer, uncovering the causes and pathogenesis as well as identifying novel biomarkers are of great significance and are desperately needed. Materials and methods: First, raw data were downloaded from the Gene Expression Omnibus database...
2018: Cancer Management and Research
https://www.readbyqxmd.com/read/29670086/mir-98-5p-contributes-to-cisplatin-resistance-in-epithelial-ovarian-cancer-by-suppressing-mir-152-biogenesis-via-targeting-dicer1
#15
Yanan Wang, Wei Bao, Yuan Liu, Shiyu Wang, Shengjie Xu, Xi Li, Yanli Li, Sufang Wu
Epithelial ovarian cancer (EOC) is a highly lethal gynecological malignancy, and cisplatin resistance is usually correlated with the poor prognosis of EOC. Increasing evidence indicates that the dysregulation of miRNAs is related to chemotherapy sensitivity. In this study, we revealed that miR-98-5p, a member of the let-7 family, was enriched in cisplatin-resistant EOC cells compared with cisplatin-sensitive cells, and could promote cisplatin resistance in EOC cells. Further studies showed that miR-98-5p could directly target the 3'-UTR of Dicer1 and suppress its expression, causing global miRNA downregulation...
April 18, 2018: Cell Death & Disease
https://www.readbyqxmd.com/read/29668476/factors-that-influence-surgical-margin-state-in-patients-undergoing-cold-knife-conization-a-single-center-experience
#16
Igor Aluloski, Mile Tanturovski, Gordana Petrusevska, Rubens Jovanovic, Slavica Kostadinova-Kunovska
AIM: To evaluate the factors that influence the surgical margin state in patients undergoing cold knife conization at the University Clinic of Gynecology and Obstetrics in Skopje, Republic of Macedonia Materials and methods: We have retrospectively analyzed the medical records of all patients that underwent a cold knife conization at our Clinic in 2015. We cross-referenced the surgical margin state with the histopathological diagnosis (LSIL, HSIL or micro-invasive/invasive cancer), menopausal status of the patients, number of pregnancies, surgeon experience, operating time and cone depth...
December 1, 2017: Prilozi (Makedonska Akademija Na Naukite i Umetnostite. Oddelenie za Medicinski Nauki)
https://www.readbyqxmd.com/read/29668367/which-patients-with-cervical-squamous-cell-carcinoma-might-benefit-from-neoadjuvant-chemotherapy
#17
Omar Mahmoud, Mark H Einstein
The Oncology Grand Rounds series is designed to place original reports published in the Journal into clinical context. A case presentation is followed by a description of diagnostic and management challenges, a review of the relevant literature, and a summary of the authors' suggested management approaches. The goal of this series is to help readers better understand how to apply the results of key studies, including those published in Journal of Clinical Oncology, to patients seen in their own clinical practice...
April 18, 2018: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/29668354/effect-of-pulsed-high-intensity-laser-therapy-on-pain-adhesions-and-quality-of-life-in-women-having-endometriosis-a-randomized-controlled-trial
#18
Ali Abd El-Monsif Thabet, Mansour Abdullah Alshehri
OBJECTIVE: The purpose of this study was to assess the effectiveness of pulsed high-intensity laser therapy on pain, adhesions, and quality of life in women with endometriosis. BACKGROUND DATA: Endometriosis is among the most common gynecological problems affecting females of childbearing age. The majority of women with endometriosis seek treatment to alleviate pain. MATERIALS AND METHODS: The sample included 40 women with endometriosis to either a mild or a moderate degree aged between 24 and 32 years...
April 18, 2018: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/29668349/climacteric-women-at-work-what-lurks-behind-poor-occupational-quality-of-life
#19
Tatjana Gazibara, Biljana Rancic, Sanja Radovanovic, Ilma Kurtagic, Selmina Nurkovic, Nikolina Kovacevic, Jelena Dotlic
Physical and psychological changes during menopausal transition may affect various aspects of everyday functioning including women's work ability and work productivity. Presence of menopausal symptoms has been well-acknowledged to negatively affect quality of life (QOL). However, data on factors associated with occupational QOL among women at this period of life are lacking. The authors' purpose in this study was to evaluate factors affecting occupational QOL in a sample of employed mid-life women who are experiencing menopause...
April 18, 2018: Health Care for Women International
https://www.readbyqxmd.com/read/29668046/black-cohosh-extracts-and-powders-induce-micronuclei-a-biomarker-of-genetic-damage-in-human-cells
#20
Stephanie L Smith-Roe, Carol D Swartz, Kim G Shepard, Steven M Bryce, Stephen D Dertinger, Suramya Waidyanatha, Grace E Kissling, Scott S Auerbach, Kristine L Witt
Black cohosh extract (BCE) is a widely used dietary supplement marketed to women to alleviate symptoms of gynecological ailments, yet its toxicity has not been well characterized. The National Toxicology Program (NTP) previously reported significant increases in micronucleated erythrocytes in peripheral blood of female Wistar Han rats and B6C3F1/N mice administered 15-1,000 mg BCE/kg/day by gavage for 90 days. These animals also developed a dose-dependent nonregenerative macrocytic anemia characterized by clinical changes consistent with megaloblastic anemia...
April 18, 2018: Environmental and Molecular Mutagenesis
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