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https://www.readbyqxmd.com/read/28099362/laparoscopic-pancreaticoduodenectomy-in-a-92-older-chinese-patient-for-cancer-of-head-of-the-pancreas-a-case-report
#1
Jiayu Zhou, Chang Xin, Tao Xia, Yiping Mou, Xiaowu Xu, Renchao Zhang, Yucheng Zhou, Weiwei Jin, Chao Lu
INTRODUCTION: Laparoscopic pancreaticoduodenectomy (LPD) is one of the most complex gastrointestinal procedures performed in laparoscopic abdominal surgery. However, the concern for elderly undergoing LPD remains. To the best of our knowledge, there are no reports describing LPD for A-92-older patient. This study aimed to share the experience of a tertiary pancreatic center and confirm the safety, feasibility of LPD for the elderly. METHOD: The patient had complained of 6-months history of abdominal discomfort and progressive jaundice...
January 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28099125/meningococcal-acwy-vaccine-uptake-and-awareness-among-student-freshers-enrolled-at-northern-ireland-universities
#2
Peter J A Moore, B Cherie Millar, John E Moore
A new MenACWY conjugate meningococcal vaccination programme was introduced in Northern Ireland (NI) in August 2015, for 13-18 year olds, as well as for first-time university entrants up to 25 years. This reflected the response made by Public Health England, due to the recent rapid increase of meningococcal group W (MenW) disease and on advice of the UK Joint Committee on Vaccination and Immunisation (JCVI). The aims of this study were to evaluate (i) the uptake of the MenACWY vaccine among first-time university students, (ii) vaccine and meningitis awareness, (iii) optimal communication modalities via a multidisciplinary team (MDT) model and (iv) current international vaccination policies relating to non-UK students...
January 18, 2017: International Journal of Adolescent Medicine and Health
https://www.readbyqxmd.com/read/28068867/training-rehabilitation-teams-in-sexual-health-care-a-description-and-evaluation-of-a-multidisciplinary-intervention
#3
Riet Pieters, Harald Kedde, Jim Bender
BACKGROUND: Sexual health problems are more prevalent among people with a chronic illness or physical disability than among the general population. Although sexual health care in the rehabilitation setting in the Netherlands is a growing field of interest, integrating sexual health in the overall care for rehabilitation patients has proven to be a challenge. METHODS: This article describes a training designed for rehabilitation professionals working in operational multidisciplinary teams...
January 9, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28050248/management-of-achalasia-in-the-uk-do-we-need-new-guidelines
#4
REVIEW
Jihene El Kafsi, Antonio Foliaki, Thomas C B Dehn, Nicholas D Maynard
AIM: It is recommended that management of complex benign upper gastrointestinal pathology is discussed at multi disciplinary team (MDT) meetings. American College of Gastroenterology (ACG) guidelines further recommend that treatment delivery is provided by high volume centres, with objective post-procedural investigations, in order to improve patient outcomes. We aimed to survey the current UK practice in the management of achalasia. METHODS: 443 Upper gastrointestinal (UGI) specialist surgeons throughout the UK were sent a surveymonkey...
December 2016: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/28048197/su-f-j-175-evaluation-of-metal-artifact-reduction-algorithms-in-computed-tomography-and-their-application-to-radiation-therapy-treatment-planning
#5
H Norris, D Rangaraj, S Kim
PURPOSE: High-Z (metal) implants in CT scans cause significant streak-like artifacts in the reconstructed dataset. This results in both inaccurate CT Hounsfield units for the tissue as well as obscuration of the target and organs at risk (OARs) for radiation therapy planning. Herein we analyze two metal artifact reduction algorithms: GE's Smart MAR and a Metal Deletion Technique (MDT) for geometric and Hounsfield Unit (HU) accuracy. METHODS: A CT-to-electron density phantom, with multiple inserts of various densities and a custom Cerrobend insert (Zeff=76...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28017583/three-dimensional-contrast-enhanced-ultrasound-improves-endoleak-detection-and-classification-after-endovascular-aneurysm-repair
#6
Christopher Lowe, Abeera Abbas, Steven Rogers, Lee Smith, Jonathan Ghosh, Charles McCollum
BACKGROUND: Three-dimensional contrast-enhanced ultrasound (3D-CEUS) is a novel technology allowing surgeons to view duplex ultrasound images in three dimensions with ultrasound contrast highlighting blood flow in endoleaks after endovascular aneurysm repair (EVAR). It potentially reduces the need for computed tomography angiography (CTA) and catheter angiography. This study compares 3D-CEUS with both CTA and the final vascular multidisciplinary team (MDT) diagnosis using all available imaging...
December 22, 2016: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28008644/test-retest-reliability-of-quantitative-sensory-testing-for-mechanical-somatosensory-and-pain-modulation-assessment-of-masticatory-structures
#7
Yuri M Costa, Orlando Morita-Neto, Everardo N S de Araújo-Júnior, Fernanda A Sampaio, Paulo César R Conti, Leonardo R Bonjardim
BACKGROUND: Assessing the reliability of medical measurements is a crucial step toward the elaboration of an applicable clinical instrument. There are few studies that evaluate the reliability of somatosensory assessment and pain modulation of masticatory structures. OBJECTIVES: To estimate the test-retest reliability, i.e., over time, of the mechanical somatosensory assessment of anterior temporalis, masseter and temporomandibular joint (TMJ) and the conditioned pain modulation (CPM) using the anterior temporalis as the test site...
December 23, 2016: Journal of Oral Rehabilitation
https://www.readbyqxmd.com/read/28004254/identification-of-novel-newcastle-disease-virus-sub-genotype-vii-j-based-on-the-fusion-protein
#8
Majid Esmaelizad, Vafa Mayahi, Maryam Pashaei, Hossein Goudarzi
Newcastle disease virus (NDV) is believed to be the cause of fatal poultry disease worldwide. The fusion (F) protein plays a key role in virus pathogenesis, and it is also used for Newcastle disease virus classification. In this study, we determined the complete coding sequence of the F gene in new velogenic NDV isolates with an intravenous pathogenicity index (IVPI) of 1.8 and a mean death time (MDT) of 72 or 48 h. Complete sequences of the F genes of new Iranian isolates were amplified and sequenced in both directions...
December 21, 2016: Archives of Virology
https://www.readbyqxmd.com/read/27965858/development-and-feasibility-of-a-swallowing-intervention-package-sip-for-patients-receiving-radiotherapy-treatment-for-head-and-neck-cancer-the-sip-study-protocol
#9
Mary Wells, Emma King, Kate Toft, Fiona MacAulay, Joanne Patterson, Nadine Dougall, Nick Hulbert-Williams, Sally Boa, Eleanor Slaven, Julie Cowie, John McGarva, Patricia Gail Niblock, Julie Philp, Justin Roe
BACKGROUND: Head and neck cancer (HNC) is the sixth most common cancer worldwide, and the functional, psychological and social consequences of HNC cancer and its treatment can be severe and chronic. Dysphagia (swallowing problems) affects up to two thirds of patients undergoing combined chemoradiotherapy. Recent reviews suggest that prophylactic swallowing exercises may improve a range of short- and long-term outcomes; however, the importance of psychological and behavioural factors on adherence to swallowing exercises has not been adequately studied...
2016: Pilot and Feasibility Studies
https://www.readbyqxmd.com/read/27956822/immediate-improvement-in-the-cranio-cervical-flexion-test-associated-with-mdt-based-interventions-a-case-report
#10
Hiroshi Takasaki, Scott Herbowy
The patient in this case study presented with constant idiopathic neck pain and left lower scapular pain (greater than 3 months) and was treated based on the principles of Mechanical Diagnosis and Therapy (MDT). Retraction exercises produced centralization of the lower scapular pain to the upper part of the scapula at the initial visit. At the first visit, the performance level on the Cranio-Cervical Flexion Test (CCFT) was ≤20 mmHg before the treatment. At the conclusion of the treatment during which centralization occurred, the CCFT level improved to 24 mmHg...
December 2016: Journal of Manual & Manipulative Therapy
https://www.readbyqxmd.com/read/27956819/measurement-of-outcomes-for-patients-with-centralising-versus-non-centralising-neck-pain
#11
Terrence Rose, Joshua Butler, Nicholaus Salinas, Ryan Stolfus, Tanisha Wheatley, Ron Schenk
OBJECTIVE: The purpose of this study is to determine whether individuals with neck pain who demonstrate centralisation of symptoms have more favourable outcome than individuals who do not demonstrate centralisation. METHODS: Eleven subjects with neck pain were evaluated and treated by two physical therapists certified in Mechanical Diagnosis and Therapy (MDT). Eleven physical therapy patients underwent a routine initial evaluation and were treated 2-3 times per week using MDT principles and other physical therapy interventions...
December 2016: Journal of Manual & Manipulative Therapy
https://www.readbyqxmd.com/read/27955816/-reappraisal-role-of-locoregional-radiation-therapy-in-metastatic-cancers
#12
REVIEW
Chloé Rancoule, Cécile Pacaut-Vassal, Alexis Vallard, Benoite Mery, Jane-Chloé Trone, Anis El Meddeb Hamrouni, Nicolas Magné
Recent innovations in oncology area helped to improve the prognosis of certain cancers including metastatic ones with a decrease in mortality. Recommendations describe the treatment of metastatic cancer as systemic therapy or complementary care and the role of locoregional treatment in the treatment plan only occurs in a palliative context. Currently, in the clinical practice, out of "the evidence based medicine", an early locoregional therapy (surgery or radiation therapy) can be proposed in several cases of metastatic cancers...
December 9, 2016: Bulletin du Cancer
https://www.readbyqxmd.com/read/27939324/understanding-the-role-of-the-parkinson-s-disease-nurse-specialist-in-the-delivery-of-apomorphine-therpy
#13
Roongroj Bhidayasiri, Kamolwan Boonpang, Onanong Jitkritsadakul, Susan M Calne, Tove Henriksen, Sally Trump, Suchapit Chaiwong, Phenprapa Susang, Nonglak Boonrod, Jirada Sringean, Teus van Laar, Martje Drent, K Ray Chaudhuri
Optimal care of Parkinson's disease (PD) patients should involve a multidisciplinary team (MDT) of which a PD nurse specialist (PDNS) is a key member. The role of a PDNS is particularly prominent in the care of advanced PD patients suitable for apomorphine because, in addition to nursing skills, apomorphine treatment requires liaison, training, interaction and coordination with patients, caregivers and other members of the MDT as well as the interface with primary care physicians. The therapeutic success of apomorphine therapy depends not only upon the pharmacologic drug response, but also on how well the patient understands his/her disease and how to handle the therapy...
December 2016: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/27935144/a-bio-chemosynthetic-approach-to-superparamagnetic-iron-oxide-ansamitocin-conjugates-for-use-in-magnetic-drug-targeting-mdt
#14
Andreas Kirschning, Liang-Liang Wang, Katja Seidel, David Candito, Michael Ott, Yu Xie, Asha Balakrishnan, Nadja-Carola Bigall, Jan Frederick Miethe
A combination of mutasynthesis using a mutant strain of A. pretiosum blocked in the biosynthesis of AHBA and semisynthesis relying on a Stille cross-coupling step provided access to new ansamitocin derivatives of which one was attached via a thermolabile linker to nanostructured iron oxide particles. When exposed to an oscillating electromagnetic field the resulting iron oxide/ansamitocin conjugate 19 heats up in an aqueous suspension and the ansamitocin derivative 16 is released by means of a retro Diels-Alder reaction...
December 9, 2016: Chemistry: a European Journal
https://www.readbyqxmd.com/read/27933155/a-quality-improvement-initiative-on-the-management-of-osteoporosis-in-older-people-with-parkinsonism
#15
Inderpal Singh, Rachel Fletcher, Linda Scanlon, Mandy Tyler, Shridhar Aithal
The risk of falls is higher in patients with people with Parkinsonism (PwP) compared to those without Parkinsonism, and leads to adverse outcomes including fragility fractures. Osteoporosis is under-recognised, and the prevalence of fragility fractures in not well studied. The primary aim of this project is for 100% of new patient referrals to, and 80% of follow up patients within the movement disorder (MD) service with osteoporosis to be treated in accordance with evidence based osteoporosis guidance. Routinely captured information regarding demographics and fragility fractures was retrospectively extracted from the clinical workstation, clinic letters, and clinical coding between July and November 2015...
2016: BMJ Quality Improvement Reports
https://www.readbyqxmd.com/read/27928786/-implementation-of-multidisciplinary-team-in-the-diagnosis-and-treatment-of-gastroenteropancreatic-neuroendocrine-neoplasm
#16
Panpan Zhang, Lin Shen
Multidisciplinary team(MDT) has been considered as the best practice in the treatment planning and care for patients with cancer around the world. With the increased range and number of specialists involved, multidisciplinary coordination and communication have been enhanced, and the efficiency and quality of diagnosis and treatment of cancer have been improved. Neuroendocrine neoplasm (NEN) is a heterogeneous group of tumors originating from neuroendocrine cells located throughout the body, most of which is gastroenteropancreatic neuroendocrine neoplasm (GEP-NEN)...
November 25, 2016: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/27919284/can-baseline-ml-flow-test-results-predict-leprosy-reactions-an-investigation-in-a-cohort-of-patients-enrolled-in-the-uniform-multidrug-therapy-clinical-trial-for-leprosy-patients-in-brazil
#17
Emerith Mayra Hungria, Regiane Morillas Oliveira, Gerson Oliveira Penna, Lúcio Cartaxo Aderaldo, Maria Araci de Andrade Pontes, Rossilene Cruz, Heitor de Sá Gonçalves, Maria Lúcia Fernandes Penna, Ligia Regina Franco Sansigolo Kerr, Mariane Martins de Araújo Stefani, Samira Bührer-Sékula
BACKGROUND: The predictive value of the serology to detection of IgM against the Mycobacterium leprae-derived phenolic glycolipid-I/PGL-I to identify leprosy patients who are at higher risk of developing reactions remains controversial. Whether baseline results of the ML Flow test can predict leprosy reactions was investigated among a cohort of patients enrolled in The Clinical Trial for Uniform Multidrug Therapy for Leprosy Patients in Brazil (U-MDT/CT-BR). METHODS: This was a descriptive study focusing on the main clinical manifestations of leprosy patients enrolled in the U-MDT/CT-BR from March 2007 to February 2012 at two Brazilian leprosy reference centers...
December 6, 2016: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/27915270/chemoprevention-of-spontaneous-ovarian-cancer-in-the-domestic-hen
#18
E H Mocka, R A Stern, O J Fletcher, K E Anderson, J N Petitte, P E Mozdziak
The hen is an attractive animal model for in vivo testing of agents that thwart ovarian carcinogenesis because ovarian cancer in the domestic hen features clinical and molecular alterations that are similar to ovarian cancer in humans, including a high incidence of p53 mutations. The objective of the study was to test the potential ovarian cancer chemopreventive effect of the p53 stabilizing compound CP-31398 on hens that spontaneously present the ovarian cancer phenotype. Beginning at 79 wk of age, 576 egg-laying hens (Gallus domesticus) were randomized to diets containing different amounts of CP-31398 for 94 wk, 5 d, comprising a control group (C) (n = 144), which was fed a diet containing 0 ppm (mg/kg) of CP-31398; a low-dose treatment (LDT) group (n = 144), which was fed a diet containing 100 ppm of CP-31398; a moderate-dose treatment (MDT) group (n = 144) which was fed a diet containing 200 ppm of CP-31398; and a high-dose treatment (HDT) group (n = 144), which was fed a diet containing 300 ppm of CP-31398...
December 3, 2016: Poultry Science
https://www.readbyqxmd.com/read/27905893/computational-prediction-of-multidisciplinary-team-decision-making-for-adjuvant-breast-cancer-drug-therapies-a-machine-learning-approach
#19
Frank P Y Lin, Adrian Pokorny, Christina Teng, Rachel Dear, Richard J Epstein
BACKGROUND: Multidisciplinary team (MDT) meetings are used to optimise expert decision-making about treatment options, but such expertise is not digitally transferable between centres. To help standardise medical decision-making, we developed a machine learning model designed to predict MDT decisions about adjuvant breast cancer treatments. METHODS: We analysed MDT decisions regarding adjuvant systemic therapy for 1065 breast cancer cases over eight years. Machine learning classifiers with and without bootstrap aggregation were correlated with MDT decisions (recommended, not recommended, or discussable) regarding adjuvant cytotoxic, endocrine and biologic/targeted therapies, then tested for predictability using stratified ten-fold cross-validations...
December 1, 2016: BMC Cancer
https://www.readbyqxmd.com/read/27900174/physical-and-functional-outcomes-following-multidisciplinary-residential-rehabilitation-for-prearthritic-hip-pain-among-young-active-uk-military-personnel
#20
Russell J Coppack, James L Bilzon, Andrew K Wills, Ian M McCurdie, Laura K Partridge, Alastair M Nicol, Alexander N Bennett
BACKGROUND: There are no studies describing the clinical outcomes of a residential, multidisciplinary team (MDT) rehabilitation intervention for patients with prearthritic hip pain. The aim of this cohort study was to describe the functional and physical outcomes of multidisciplinary residential rehabilitation for UK military personnel with prearthritic hip pain. METHODS: Participants (N=40) with a mean age of 33 years referred to a specialist residential rehabilitation centre completed a comprehensive multidisciplinary residential intervention...
2016: BMJ Open Sport & Exercise Medicine
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