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https://www.readbyqxmd.com/read/28515041/multidisciplinary-evaluation-of-interstitial-lung-diseases-current-insights-number-1-in-the-series-radiology-edited-by-nicola-sverzellati-and-sujal-desai
#1
Simon L F Walsh
Multidisciplinary team (MDT) diagnosis is regarded as the diagnostic reference standard for interstitial lung disease (ILD). Several studies have reported that MDT diagnosis is associated with higher levels of diagnostic confidence and better interobserver agreement when compared to the individual components of the MDT in isolation. Although this recommendation is widely accepted, no guideline statement specifies what constitutes an MDT meeting and how its participants should govern it. Furthermore, the precise role of an MDT meeting in the setting of ILD may vary from one group to another...
June 30, 2017: European Respiratory Review: An Official Journal of the European Respiratory Society
https://www.readbyqxmd.com/read/28480659/daily-mean-temperature-and-urolithiasis-presentation-in-six-cities-in-korea-time-series-analysis
#2
Byung Hoon Chi, In Ho Chang, Se Young Choi, Dong Churl Suh, Chong Won Chang, Yun Jung Choi, Seo Yeon Lee
Seasonal variation in urinary stone presentation is well described in the literature. However, previous studies have some limitations. To explore overall cumulative exposure-response and the heterogeneity in the relationships between daily meteorological factors and urolithiasis incidence in 6 major Korean cities, we analyzed data on 687,833 urolithiasis patients from 2009 to 2013 for 6 large cities in Korea: Seoul, Incheon, Daejeon, Gwangju, Daegu, and Busan. Using a time-series design and distributing lag nonlinear methods, we estimated the relative risk (RR) of mean daily urolithiasis incidence (MDUI) associated with mean daily meteorological factors, including the cumulative RR for a 20-day period...
June 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28470785/formation-of-nanoparticle-ternary-group-11-cu-ag-bismuth-sulfides-and-au-0-utilizing-bismuth-dithioates-under-mild-conditions
#3
Dimuthu C Senevirathna, Melissa Vivienne Werrett, Narendra Pai, Victoria L Blair, Leone Spiccia, Philip C Andrews
The formation of mixed metal sulfides of AgBiS2 and Cu3BiS2 via a simple two-step process utilizing bismuth dithioates as single source Bi and S precursors is described. Sono-chemical reaction of Bi2O3 with six different aryldithioc acids (benzodithioic, BDT-H; 4-methoxybenzodithioic, 4-MBDT-H; 3-methylbenzodithioic, 3-MBDT-H; 2-mesitylenedithioic, 2-MDT-H; 4-fluorobenzodithioic, 4-FBDT-H; and 2-thiophenedithioic, 2-TDT-H) resulted in the following complexes; [Bi(BDT)3] 1, [Bi(4-MBDT)3] 2, [{Bi(3-MBDT)3}2·C7H8] (32·C7H8), [Bi(2-MDT)3] 4, [Bi(4-FBDT)3] 5 and [Bi(2-TDT)3] 6...
May 3, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28460212/outcome-of-head-and-neck-cancer-patients-who-did-not-receive-curative-intent-treatment
#4
Deegesh Shah, Gary R Hoffman
PURPOSE: There exists a subgroup of patients with head and neck cancer (HNC) who neither warrant nor request curative-intent treatment and who progress to a terminal-care paradigm. The purpose of this study was to determine the frequency of and reasons for an HNC terminal-care referral and the time to and place of death for such patients. MATERIALS AND METHODS: The authors undertook a retrospective cohort study of all attendees with HNC who had undergone multidisciplinary team (MDT) assessment at the Calvary Mater Hospital (Newcastle, Australia) from January 2013 through December 2014...
April 6, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28459759/managing-dysphagia-in-trachesotomized-patients-where-are-we-now
#5
Diane Goff
PURPOSE OF REVIEW: Tracheostomized patients are medically complex and vulnerable. International attention is now focused on improving the safety and quality of their care. This review summarizes recent evidence in hot-topic areas pertinent to speech and language therapy (SLT) intervention for dysphagia management in tracheostomized patients. RECENT FINDINGS: The management of tracheostomized patients requires a truly multidisciplinary team (MDT) approach. Without this, patients remain tracheostomized and hospitalized for longer and have slower access to MDT members...
June 2017: Current Opinion in Otolaryngology & Head and Neck Surgery
https://www.readbyqxmd.com/read/28458541/selection-of-potential-iron-oxide-nanoparticles-for-breast-cancer-treatment-based-on-in-vitro-cytotoxicity-and-cellular-uptake
#6
Johanna M Poller, Jan Zaloga, Eveline Schreiber, Harald Unterweger, Christina Janko, Patricia Radon, Dietmar Eberbeck, Lutz Trahms, Christoph Alexiou, Ralf P Friedrich
Superparamagnetic iron oxide nanoparticles (SPIONs) are promising tools for the treatment of different diseases. Their magnetic properties enable therapies involving magnetic drug targeting (MDT), hyperthermia or imaging. Depending on the intended treatment, specific characteristics of SPIONs are required. While particles used for imaging should circulate for extended periods of time in the vascular system, SPIONs intended for MDT or hyperthermia should be accumulated in the target area to come into close proximity of, or to be incorporated into, specific tumor cells...
2017: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/28438129/severe-type-1-upgrading-leprosy-reaction-in-a-renal-transplant-recipient-a-paradoxical-manifestation-associated-with-deficiency-of-antigen-specific-regulatory-t-cells
#7
Ana Paula Vieira, Maria Angela Bianconcini Trindade, Flávio Jota de Paula, Neusa Yurico Sakai-Valente, Alberto José da Silva Duarte, Francine Brambate Carvalhinho Lemos, Gil Benard
BACKGROUND: Due to its chronic subclinical course and large spectrum of manifestations, leprosy often represents a diagnostic challenge. Even with proper anti-mycobacteria treatment, leprosy follow up remains challenging: almost half of leprosy patients may develop reaction episodes. Leprosy is an infrequent complication of solid organ transplant recipients. This case report illustrates the challenges in diagnosing and managing leprosy and its reactional states in a transplant recipient...
April 24, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28437507/effects-of-experimental-pain-and-lidocaine-on-mechanical-somatosensory-profile-and-face-perception
#8
Yuri Martins Costa, Eduardo E Castrillon, Leonardo Rigoldi Bonjardim, Paulo César Rodrigues Conti, Lene Baad-Hansen, Peter Svensson
AIMS: To assess the effects of experimental muscle pain and topical lidocaine applied to the skin overlying the masseter muscle on the mechanical somatosensory profile and face perception of the masseter muscle in healthy participants. METHODS: A total of 28 healthy participants received a 45-minute application of a lidocaine or placebo patch to the skin overlying the masseter muscle followed by one injection of 0.2 mL sterile solution of monosodium glutamate. Measurements were taken four times during each session of quantitative sensory testing (QST) (T0 = baseline, T1 = 45 minutes after patch application, T2 = immediately after glutamate injection, and T3 = 25 minutes after the glutamate injection), and the following variables were measured: mechanical detection threshold (MDT), mechanical pain threshold (MPT), pressure pain threshold (PPT), pain report (pain on palpation, pain spreading on palpation, and pain intensity), pain drawing, and perceptual distortion...
April 2017: Journal of Oral & Facial Pain and Headache
https://www.readbyqxmd.com/read/28435194/molecular-characterization-of-velogenic-viscerotropic-ranikhet-newcastle-disease-virus-from-different-outbreaks-in-desi-chickens
#9
V S Dhaygude, G K Sawale, M M Chawak, N R Bulbule, S D Moregaonkar, D S Gavhane
AIM: Diagnosis of velogenic viscerotropic Ranikhet disease from six different flocks of desi chicken in and around Mumbai by gross and histopathological examination, isolation of virus and molecular methods. MATERIALS AND METHODS: A total of 25 carcasses (varying between 2 and 6 carcasses from each flock) of six different flocks of adult desi chicken were subjected to necropsy examination for diagnosis of the disease during the span of a year (2014-2015). After thorough gross examination, the tissue samples were collected and processed for virus isolation and histopathological examination...
March 2017: Veterinary World
https://www.readbyqxmd.com/read/28427439/prevalence-and-prognostic-implications-of-psychological-distress-in-patients-with-gastric-cancer
#10
Gun Min Kim, Seung Jun Kim, Su Kyung Song, Hye Ryun Kim, Beo Deul Kang, Sung Hoon Noh, Hyun Cheol Chung, Kyung Ran Kim, Sun Young Rha
BACKGROUND: The aim of this study was to investigate the prevalence and prognostic significance of psychological distress in gastric cancer patients. METHODS: The study population included 229 gastric cancer patients visiting Yonsei Cancer Center between November 2009 and March 2011. The distress was measured by available tools including the Modified Distress Thermometer (MDT), Hospital Anxiety and Depression Scale (HADS), and Center for Epidemiologic Studies-Depression Scale (CES-D)...
April 20, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28416852/-first-aid-system-for-trauma-development-and-status
#11
D K Chen, W C Lin, P Zhang, S J Kuang, W Huang, T B Wang
With the great progress of the economy, the level of industrialization has been increasing year by year, which leads to an increase in accidental trauma accidents. Chinese annual death of trauma is already more than 400 000, which makes trauma the fifth most common cause of death, following malignant tumor, heart, brain and respiratory diseases. Trauma is the leading cause of the death of young adults. At the same time, trauma has become a serious social problem in peace time. Trauma throws great treats on human health and life...
April 18, 2017: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/28407278/prevention-and-treatment-of-complications-of-selective-internal-radiation-therapy-expert-guidance-and-systematic-review
#12
REVIEW
Bruno Sangro, Diego Martínez-Urbistondo, Lourens Bester, Jose I Bilbao, Douglas M Coldwell, Patrick Flamen, Andrew Kennedy, Jens Ricke, Ricky A Sharma
Selective internal radiation therapy (SIRT or radioembolisation) by intraarterial injection of radioactive yttrium-90 ((90) Y)-loaded microspheres is increasingly used for the treatment of patients with liver metastases or primary liver cancer. The high-dose beta-radiation penetrates an average of only 2.5 mm from the source so that its effects are limited to the site of delivery. However the off-target diversion of (90) Y microspheres to tissues other than the tumor may lead to complications. The most prominent ones include: radiation gastritis and gastrointestinal (GI) ulcers, cholecystitis, radiation pneumonitis, and radioembolisation-induced liver disease (REILD)...
April 13, 2017: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
https://www.readbyqxmd.com/read/28402593/a-new-method-for-the-production-of-sterile-colonies-of-lucilia-sericata
#13
N E Gasz, M L Harvey
Maggot debridement therapy (MDT) refers to the use of blowfly larvae to clean or debride an infected wound. Most commonly, larvae of Lucilia sericata (Meigen) (Diptera: Calliphoridae) are used, and are sterilized prior to use to ensure no further bacterial infections are introduced during treatment. Current methods sterilize eggs from laboratory-reared blowfly colonies, after which sterile early second instar maggots can be provided to hospitals for use in treatment. Maggots not required for treatment are used for colony regeneration, in which sterility is not maintained...
April 12, 2017: Medical and Veterinary Entomology
https://www.readbyqxmd.com/read/28396900/multidisciplinary-team-approach-to-traumatic-spinal-cord-injuries-a-single-institution-s-quality-improvement-project
#14
Georgina Alizo, Jason D Sciarretta, Stefanie Gibson, Keely Muertos, Sharon Holmes, Felicia Denittis, Joseph Cheatle, John Davis, Antonio Pepe
BACKGROUND: A stepwise multidisciplinary team (MDT) approach to the injured trauma patient has been reported to have an overall benefit, with reduction in mortality and improved morbidity. Based on clinical experience, we hypothesized that implementation of a dedicated Spinal Cord Injury Service (SCIS) would impact outcomes of a patient specific population on the trauma service. METHODS: The trauma center registry was retrospectively queried, from January 2011 through December 2015, for patients presenting with a spinal cord injury...
April 10, 2017: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
https://www.readbyqxmd.com/read/28377150/developmental-changes-in-autonomic-responses-are-associated-with-future-reward-punishment-expectations-a-study-of-sympathetic-skin-responses-in-the-markov-decision-task
#15
Hiromi Hosaka, Kakuro Aoyagi, Yoshimi Kaga, Hideaki Kanemura, Kanji Sugita, Masao Aihara
OBJECTIVE: Autonomic nervous system activity is recognized as a major component of emotional responses. Future reward/punishment expectations depend upon the process of decision making in the frontal lobe, which is considered to play an important role in executive function. The aim of this study was to investigate the relationship between autonomic responses and decision making during reinforcement tasks using sympathetic skin responses (SSR). METHODS: Nine adult and 9 juvenile (mean age, 10...
April 1, 2017: Brain & Development
https://www.readbyqxmd.com/read/28375119/physical-characterization-and-dissolution-performance-assessment-of-etravirine-solid-dispersions-prepared-by-spray-drying-process
#16
Pavan Kommavarapu, Arthanareeswari Maruthapillai, Kamaraj Palanisamy, Ravi Teja Koya
The aim of the current exertion was to prepare Solid Dispersion of Etravirine by Spray drying technique to enhance aqueous solubility and dissolution rate. Solid dispersions (SD) of Etravirine were prepared using Copovidone and Povidone-Copovidone in dichloromethane and physical properties were characterized by Scanning electron microscopy (SEM), X-Ray diffractometry (PXRD), Fourier Transform Infrared Spectroscopy (FTIR), Differential Scanning Calorimetry (DSC). SD's were evaluated for equilibrium solubility and in vitro drug release profile by dissolution testing...
November 2016: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28370156/sensory-recovery-of-non-innervated-free-flaps-and-nasolabial-island-flaps-used-for-tongue-reconstruction-of-oncological-defects
#17
Ling Zhu, Jinglu Zhang, Xiaomeng Song, Wei Hou, Song Wu, Wenjing Chen, Peter Svensson, Kelun Wang
OBJECTIVES: The aims of this study were to assess sensory recovery and impact on life quality after tongue reconstruction of oncological defects using different flap types. MATERIALS AND METHODS: Thirty-two patients who underwent tongue reconstruction for oncological defects 9.3 months after surgery with non-innervated radial forearm free flaps (RFFFs) (N=16), non-innervated anterolateral thigh free flaps (ALTFFs) (N=8) and nasolabial island flaps (NLIFs) (N=8), and 20 age- and gender-matched healthy controls participated in the study...
March 28, 2017: Journal of Oral Rehabilitation
https://www.readbyqxmd.com/read/28361272/sterilization-of-blow-fly-eggs-chrysomya-megacephala-and-lucilia-cuprina-diptera-calliphoridae-for-maggot-debridement-therapy-application
#18
Kwankamol Limsopatham, Phadungkiat Khamnoi, Kabkaew L Sukontason, Dheerawan Boonyawan, Tarinee Chaiwong, Kom Sukontason
Maggot debridement therapy (MDT) is an application of sterile laboratory-reared blow fly larvae to remove necrotic tissue and disinfect wounds for medical conditions. For effective application, the blow fly larvae used in the wound treatment are required to be in aseptic condition. Here, we report the results of a detailed assessment of bacteria and fungi isolated from the eggs of two blow fly species, Chrysomya megacephala (F.) and Lucilia cuprina (Wiedemann) before and after sterilization by disinfectants Chlorhex-C, povidone-iodine, and sodium hypochlorite...
March 30, 2017: Parasitology Research
https://www.readbyqxmd.com/read/28343263/genotypic-and-pathogenic-characterization-of-genotype-vii-newcastle-disease-viruses-isolated-from-commercial-farms-in-egypt-and-evaluation-of-heterologous-antibody-responses
#19
A M Saad, Ahmed Samy, M A Soliman, A Arafa, A Zanaty, M K Hassan, A H Sultan, A I Bazid, A H Hussein
Newcastle disease viruses (NDV) represent a major threat to poultry production worldwide. Recently in Egypt NDV circulated extensively, even in vaccinated farms. In the present study samples were collected from sixteen vaccinated broiler farms in animals exhibiting the typical gross lesions of NDV. Virus isolation and pathogenicity studies for positive samples were carried out in accordance to reference procedures and phylogenetic analysis was carried out based on partial sequences of the Fusion gene. Furthermore, in vivo investigation of the ability of heterologous antibody, induced by commercially available lentogenic strain-based vaccines, to efficiently reduce viral shedding was examined...
March 25, 2017: Archives of Virology
https://www.readbyqxmd.com/read/28339319/intrathecal-magnetic-drug-targeting-for-localized-delivery-of-therapeutics-in-the-cns
#20
Indu Venugopal, Nazia Habib, Andreas Linninger
AIM: The challenge in treating neurological diseases is not lack of drug potency, but ineffective targeting techniques. We propose a technique called intrathecal magnetic drug targeting (IT-MDT), in which intrathecally injected magnetic nanoparticles (MNPs) are targeted to specific sites using external magnets. MATERIALS & METHODS: MRI and histology confirmed localization of MNPs via IT-MDT at target sites along the spine of Sprague-Dawley rats. RESULTS: MRI results confirmed greater MNP localization when the duration of magnet application was extended...
March 24, 2017: Nanomedicine
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