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https://www.readbyqxmd.com/read/28231425/practice-patterns-regarding-multidisciplinary-cancer-management-and-suggestions-for-further-refinement-results-from-a-national-survey-in-korea
#1
Yun-Gyoo Lee, Sukjoong Oh, Heejin Kimm, Dong-Hoe Koo, Do Yeun Kim, Bong-Seog Kim, Seung-Sei Lee
Purpose: This study was conducted to explore the process and operation of a cancer multidisciplinary team (MDT) after the reimbursement decision in Korea, and to identify ways to overcome the major barriers to effective and sustainable MDTs. Materials and Methods: Approximately 1000 cancer specialists, including medical oncologists, surgical oncologists, radiation oncologists, pathologists, and radiologists in general hospitals in Korea were invited to complete the survey...
February 22, 2017: Cancer Research and Treatment: Official Journal of Korean Cancer Association
https://www.readbyqxmd.com/read/28230424/finding-our-voice-in-the-mdt
#2
Verna Lavender
No abstract text is available yet for this article.
February 23, 2017: British Journal of Nursing: BJN
https://www.readbyqxmd.com/read/28222139/leprosy-reactions-the-predictive-value-of-mycobacterium-leprae-specific-serology-evaluated-in-a-brazilian-cohort-of-leprosy-patients-u-mdt-ct-br
#3
Emerith Mayra Hungria, Samira Bührer-Sékula, Regiane Morillas de Oliveira, Lúcio Cartaxo Aderaldo, Araci de Andrade Pontes, Rossilene Cruz, Heitor de Sá Gonçalves, Maria Lúcia Fernandes Penna, Gerson Oliveira Penna, Mariane Martins de Araújo Stefani
BACKGROUND: Leprosy reactions, reversal reactions/RR and erythema nodosum leprosum/ENL, can cause irreversible nerve damage, handicaps and deformities. The study of Mycobacterium leprae-specific serologic responses at diagnosis in the cohort of patients enrolled at the Clinical Trial for Uniform Multidrug Therapy Regimen for Leprosy Patients in Brazil/U-MDT/CT-BR is suitable to evaluate its prognostic value for the development of reactions. METHODOLOGY: IgM and IgG antibody responses to PGL-I, LID-1, ND-O-LID were evaluated by ELISA in 452 reaction-free leprosy patients at diagnosis, enrolled and monitored for the development of leprosy reactions during a total person-time of 780,930 person-days, i...
February 21, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28216856/feasibility-and-acceptability-of-implementing-the-integrated-care-plan-for-the-dying-in-the-indian-setting-survey-of-perspectives-of-indian-palliative-care-providers
#4
Naveen Salins, Jeremy Johnson, Stanley Macaden
INTRODUCTION: Capacity to provide end-of-life care in India is scored as 0.6/100, and very few people in India have access to palliative and end-of-life care. Lack of end-of-life care provision in India has led to a significant number of people receiving inappropriate medical treatment at the end of life, with no access to pain and symptom control and high treatment costs. The International Collaborative for the Best Care for the Dying Person is an initiative that offers the opportunity to apply international evidence on the key factors required to provide best care for the dying in the Indian context...
January 2017: Indian Journal of Palliative Care
https://www.readbyqxmd.com/read/28199902/refinement-of-clinical-x-ray-computed-tomography-ct-scans-containing-metal-implants
#5
Graham Treece
X-ray computed tomography (CT) data contains artefacts from many sources, with sufficient prominence to affect diagnostic utility when metal is present in the scans. These artefacts can be reduced, usually by the removal and in-filling of any sinogram data which has been affected by metal, and several such techniques have been proposed. Most of them are prone to introducing new artefacts into the CT data or may take a long time to correct the data. It is the purpose of this paper to introduce a new technique which is fast, yet can effectively remove most artefacts without introducing significant new ones...
February 1, 2017: Computerized Medical Imaging and Graphics: the Official Journal of the Computerized Medical Imaging Society
https://www.readbyqxmd.com/read/28188188/locally-advanced-colon-cancer-evaluation-of-current-clinical-practice-and-treatment-outcomes-at-the-population-level
#6
Charlotte E L Klaver, Lieke Gietelink, Willem A Bemelman, Michel W J M Wouters, Theo Wiggers, Rob A E M Tollenaar, Pieter J Tanis
Background: The goal of this study was to evaluate current clinical practice and treatment outcomes regarding locally advanced colon cancer (LACC) at the population level. Methods: Data were used from the Dutch Surgical Colorectal Audit from 2009 to 2014. A total of 34,527 patients underwent resection for non-LACC and 6,918 for LACC, which was defined as cT4 and/or pT4 stage. LACC was divided into those with multivisceral resection (LACC-MV; n=3,385) and without (LACC-noMV; n=1,595). Guideline adherence, treatment strategy, and short-term outcomes were evaluated...
February 2017: Journal of the National Comprehensive Cancer Network: JNCCN
https://www.readbyqxmd.com/read/28166999/unresolved-drooling-in-a-previously-healthy-child-caused-by-a-brainstem-malignancy
#7
Fenella Shelton, Eleanor Sproson, Jana Van der Veen, Hazel Evans, Andrea Burgess, Hasnaa Ismail-Koch
Drooling occurs commonly in children below the age of two. In a small group of children this persists and an otorhinolaryngology consultation is sought. In children with no neurological abnormality or comorbidity, reassurance and behavioural management is often suggested. We present a case where drooling was the presenting feature of brain stem malignancy. Diagnosis was suggested following a sleep study demonstrating central apnoeas. Magnetic resonance imaging (MRI) showed an intra-axial brainstem tumour. This case highlights the importance of multidisciplinary team (MDT) management of children with persistent drooling of unknown cause...
March 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28165818/investigation-of-the-effect-of-solubility-increase-at-the-main-absorption-site-on-bioavailability-of-bcs-class-ii-drug-risperidone-using-liquisolid-technique
#8
Ahmed Khames
BCS class II drugs usually suffer inadequate bioavailability as dissolution step is the absorption rate limiting step. In this work, the effect of solubility increase at the main absorption site for these drugs was investigated using risperidone as a drug model. Liquisolid technique was applied to prepare risperidone per-oral tablets of high dissolution rate at intestinal pH (6.8) using versatile nonionic surfactants of high solubilizing ability [Transcutol HP, Labrasol and Labrasol/Labrafil (1:1) mixture] as liquid vehicles at different drug concentrations (10-30%) and fixed (R)...
November 2017: Drug Delivery
https://www.readbyqxmd.com/read/28156672/attitude-and-support-to-inform-clinical-predictions-of-survival-in-patients-with-advanced-cancer
#9
David L Ma, Kim Paulson, Sunita Ghosh, Bronwen LeGuerrier, Karen P Chu, Diane Severin, Fleur Huang, Sharon Watanabe, Ann Huot, John Amanie, Samir Patel, Tirath Nijjar, Ericka Wiebe, Brita Lavender Danielson, Brock J Debenham
: 39 Background: Tumour factors (eg primary site, size) helpful in prognostication in early stage cancer may be less important than patient factors, such as Karnofsky performance status (KPS), later in the disease trajectory. We evaluated the utilization of the parameters attitude (ATT) and psychosocial support (PSS) in predicting remaining lifespan by two experienced multidisciplinary teams (MDT). METHODS: After clinical assessment of consecutive patients, a quantitative clinical prediction of survival (CPS) was made prospectively, independently and anonymously by each health care provider (HCP)...
October 9, 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28145188/nurses-are-silent-in-75-of-cancer-multidisciplinary-team-meetings-study-finds
#10
(no author information available yet)
A national review of multidisciplinary team (MDT) meetings in cancer care found that nurses do not speak at all in more than three-quarters of them.
February 1, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28141578/understanding-the-dynamics-of-superparamagnetic-particles-under-the-influence-of-high-field-gradient-arrays
#11
Lester C Barnsley, Dario Carugo, Miles Aron, Eleanor Stride
The aim of this study was to characterize the behaviour of superparamagnetic particles in magnetic drug targeting (MDT) schemes. A 3-dimensional mathematical model was developed, based on the analytical derivation of the trajectory of a magnetized particle suspended inside a fluid channel carrying laminar flow and in the vicinity of an external source of magnetic force. Semi-analytical expressions to quantify the proportion of captured particles, and their relative accumulation (concentration) as a function of distance along the wall of the channel were also derived...
January 31, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28139858/geographic-and-socioeconomic-factors-in-patients-with-malignant-pleural-mesothelioma-in-new-south-wales-and-their-impact-upon-clinical-outcomes
#12
Anthony Linton, Matthew Soeberg, Richard Broome, Steven Kao, Nico van Zandwijk
BACKGROUND AND OBJECTIVE: Whilst the impact of clinicopathological factors on the prognosis of malignant pleural mesothelioma (MPM) is well understood, socioeconomic and geographic factors have received less attention. We analysed the relationship between geographic and socioeconomic factors upon survival and treatment provision in a large series of patients with MPM. METHODS: We assessed MPM patients awarded compensation between 2002 and 2009 with additional MPM incidence data from the New South Wales (NSW) Cancer Registry...
January 31, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28134478/parents-preferences-for-the-organisation-of-long-term-follow-up-of-childhood-cancer-survivors
#13
J Vetsch, C S Rueegg, L Mader, E Bergstraesser, M Diezi, C E Kuehni, G Michel
Parents take an important role in follow-up of young cancer survivors. We aimed to investigate (1) parents' preferences for organisation of follow-up (including content, specialists involved and models of care), and (2) parents' and children's characteristics predicting preference for generalist vs. specialist-led follow-up. We sent a questionnaire to parents of childhood cancer survivors aged 11-17 years. We assessed on a 4-point Likert scale (1-4), parents' preferences for organisation of long-term follow-up...
January 30, 2017: European Journal of Cancer Care
https://www.readbyqxmd.com/read/28133613/contrast-enhanced-ultrasound-guided-biopsy-of-undetermined-abdominal-lesions-a-multidisciplinary-decision-making-approach
#14
Feng Mao, Yi Dong, Zhengbiao Ji, Jiaying Cao, Wen-Ping Wang
Aim. To investigate the value of contrast-enhanced ultrasound (CEUS) guided biopsy of undetermined abdominal lesions in multidisciplinary treatment (MDT) decision-making approach. Methods. Between Jan 2012 and Dec 2015, 60 consecutive patients (male, 37; female, 23; mean age, 51.3 years ± 14.6) who presented with undetermined abdominal lesions were included. CEUS and core needle percutaneous biopsy was performed under real-time CEUS guidance in all lesions. Data were recorded and compared with conventional ultrasound (US) guidance group (n = 75)...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28131625/deficits-in-cognitive-flexibility-induced-by-chronic-unpredictable-stress-are-associated-with-impaired-glutamate-neurotransmission-in-the-rat-medial-prefrontal-cortex
#15
Julianne D Jett, Sarah E Bulin, Lauren C Hatherall, Carlie M McCartney, David A Morilak
Deficits in cognitive flexibility, the ability to modify behavior in response to changes in the environment, contribute to the onset and maintenance of stress-related neuropsychiatric illnesses, such as depression. Cognitive flexibility depends on medial prefrontal cortex (mPFC) function, and in depressed patients, cognitive inflexibility is associated with hypoactivity and decreased glutamate receptor expression in the mPFC. Rats exposed to chronic unpredictable stress (CUS) exhibit compromised mPFC function on the extradimensional (ED) set-shifting task of the attentional set-shifting test...
January 26, 2017: Neuroscience
https://www.readbyqxmd.com/read/28118417/pain-from-dental-implant-placement-inflammatory-pulpitis-pain-and-neuropathic-pain-present-different-somatosensory-profiles
#16
André Luís Porporatti, Leonardo Rigoldi Bonjardim, Juliana Stuginski-Barbosa, Estevam Augusto Bonfante, Yuri Martins Costa, Paulo César Rodrigues Conti
AIMS: To address the two following questions: (1) What kind of somatosensory abnormalities may be characterized in patients receiving dental implants (IMP), in ongoing inflammatory dental pulpitis (IP) patients, and in neuropathic pain (atypical odontalgia [AO]) patients? and (2) What sort of sensory and neural changes may result from dental implant placement surgery and pulpectomy? METHODS: A total of 60 subjects were divided into three groups: the IMP (n = 20), IP (n = 20), and AO groups (n = 20)...
January 2017: Journal of Oral & Facial Pain and Headache
https://www.readbyqxmd.com/read/28115853/the-role-and-structure-of-the-multidisciplinary-team-in-the-management-of-advanced-parkinson-s-disease-with-a-focus-on-the-use-of-levodopa-carbidopa-intestinal-gel
#17
REVIEW
Stephen W Pedersen, Martin Suedmeyer, Louis W C Liu, Dirk Domagk, Alison Forbes, Lars Bergmann, Koray Onuk, Ashley Yegin, Teus van Laar
A multidisciplinary team (MDT) approach is increasingly recommended in Parkinson's disease (PD) treatment guidelines, but no standard of care exists for such an approach, and the guidelines do not provide clarification on how it should be implemented. This paper reviews evidence of MDT interventions in people with PD and provides expert clinical perspectives for an MDT approach, with a focus on advanced PD and levodopa-carbidopa intestinal gel (carbidopa-levodopa enteral suspension in the USA). The key recommendations are to enable the best possible treatment of people with PD locally by facilitating a close structured collaboration of different health care professionals working in a fixed network structure; to refer people with PD to established MDT centers in a timely manner; to establish regular meetings for the MDT enabling interdisciplinary exchange and learning; to optimize individual treatment and carefully evaluate available treatment options; to ensure treatment decisions are agreed jointly between people with PD, their caregivers, family, and health care professional; and to include specialists outside of neurology from adjuvant medical departments as necessary when implementing advanced therapies...
2017: Journal of Multidisciplinary Healthcare
https://www.readbyqxmd.com/read/28114238/classification-of-ovarian-cancer-surgery-facilitates-treatment-decisions-in-a-gynecological-multidisciplinary-team
#18
Signe Frahm Bjørn, Tine Henrichsen Schnack, Henrik Lajer, Ib Jarle Christensen, Lene Lundvall, Lotte Nedergaard Thomsen, Claus Høgdall
OBJECTIVE: Proper planning of intervention and care of ovarian cancer surgery is of outmost importance and involves a wide range of personnel at the departments involved. The aim of this study is to evaluate the introduction of an ovarian surgery classification (COVA) system for facilitating multidisciplinary team (MDT) decisions. MATERIALS AND METHODS: Four hundred eighteen women diagnosed with ovarian cancers (n = 351) or borderline tumors (n = 66) were selected for primary debulking surgery from January 2008 to July 2013...
February 2017: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/28104032/-analysis-of-the-factors-influencing-adjuvant-chemotherapy-decisions-for-triple-negative-breast-cancer
#19
J Hong, X S Chen, J Y Wu, O Huang, L Zhu, J R He, Q Fang, W G Chen, Y F Li, K W Shen
Objective: To analyze adjuvant chemotherapy decisions for triple negative breast cancer (TNBC), and explore the influencing factors in the multidisciplinary treatment (MDT) modality. Methods: A retrospective analysis was performed. The cases with invasive TNBC who underwent surgery and MDT discussion for adjuvant treatment in Ruijin Hospital, from April 2013 to June 2015, were recruited. The patients' clinicopathological characteristics were analyzed and adjuvant treatment suggestions from MDT were obtained...
January 23, 2017: Zhonghua Zhong Liu za Zhi [Chinese Journal of Oncology]
https://www.readbyqxmd.com/read/28099362/laparoscopic-pancreaticoduodenectomy-in-a-92-older-chinese-patient-for-cancer-of-head-of-the-pancreas-a-case-report
#20
Jiayu Zhou, Chang Xin, Tao Xia, Yiping Mou, Xiaowu Xu, Renchao Zhang, Yucheng Zhou, Weiwei Jin, Chao Lu
INTRODUCTION: Laparoscopic pancreaticoduodenectomy (LPD) is one of the most complex gastrointestinal procedures performed in laparoscopic abdominal surgery. However, the concern for elderly undergoing LPD remains. To the best of our knowledge, there are no reports describing LPD for A-92-older patient. This study aimed to share the experience of a tertiary pancreatic center and confirm the safety, feasibility of LPD for the elderly. METHOD: The patient had complained of 6-months history of abdominal discomfort and progressive jaundice...
January 2017: Medicine (Baltimore)
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