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https://www.readbyqxmd.com/read/29332424/salivary-metabolomics-profile-of-patients-with-recurrent-aphthous-ulcer-as-revealed-by-liquid-chromatography-tandem-mass-spectrometry
#1
Yantao Li, Daoming Wang, Chunwei Zeng, Yichen Liu, Guangyuan Huang, Zhanlong Mei
Objective We compared the salivary nontargeted metabolite profiles between patients with recurrent aphthous ulcer (RAU) and healthy individuals to investigate the metabolic alterations associated with RAU. Methods Saliva samples were collected from 45 patients with RAU and 49 healthy individuals, and the salivary metabolites were quantified using liquid chromatography-tandem mass spectrometry. The metabolomic profiles were then analyzed using multivariate and univariate statistical methods, and enrichment of the metabolites in various biological pathways was assessed...
January 1, 2018: Journal of International Medical Research
https://www.readbyqxmd.com/read/29327097/-clinical-and-cognitive-aspects-of-functional-psychogenic-tremor
#2
REVIEW
K E Zeuner, R Schmidt, P Schwingenschuh
Functional (psychogenic) tremor is the most common functional movement disorder. Characteristic clinical features, so called red flags, can help to make the clinical distinction of this type from other tremor disorders. The most common features include the variability of frequency and amplitude. Clinical examination should include different types of distraction including motor or cognitive tasks or testing the influence of suggestibility on tremor amplitude, frequency or direction. Patients often report sudden onset and remissions that may last for months or even years...
January 11, 2018: Der Nervenarzt
https://www.readbyqxmd.com/read/29326819/association-between-bullying-and-pediatric-psychiatric-hospitalizations
#3
Hadassa Leader, Jasmine Singh, Ayesha Ghaffar, Cheryl de Silva
Objectives: Bullying is a serious public health issue. We sought to demonstrate an association between bullying victimization and hospital admissions for acute psychiatric problems. We described the demographics and types of bullying in a sample of hospitalized patients in Staten Island, NY, and compared bullying victimization scores with psychiatric versus medical admissions. Methods: Patients in grades 3-12 were recruited from the Staten Island University Hospital Inpatient Pediatrics unit and emergency department...
2018: SAGE Open Medicine
https://www.readbyqxmd.com/read/29314105/ambulatory-diagnostic-ecg-monitoring-for-syncope-and-collapse-an-assessment-of-clinical-practice-in-the-united-states
#4
David G Benditt, Wayne O Adkisson, Richard Sutton, Robin K Mears, Scott Sakaguchi
INTRODUCTION: Diagnostic ambulatory ECG (AECG) monitoring is widely used for evaluating syncope and collapse, and practice guidelines provide recommendations regarding optimal AECG device selection. However, whether physicians utilize AECGs in accordance with the pertinent guidelines is unclear. This study assessed utilization of AECG monitoring systems for syncope and collapse diagnosis by physicians in the United States. METHODS AND RESULTS: A quantitative survey was undertaken of physicians comprising multiple specialties (Emergency Room, n = 35; Primary care, n = 35; Hospitalists, n = 30; Neurologists, n = 30; non-implanting, n = 34 and implanting-Cardiologists, n = 35)...
January 4, 2018: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/29309953/facial-emotion-processing-in-patients-with-seizure-disorders
#5
Jerzy P Szaflarski, Jane B Allendorfer, Rodolphe Nenert, W Curt LaFrance, Helen I Barkan, Jennifer DeWolfe, Sandipan Pati, Ashley E Thomas, Lawrence Ver Hoef
Studies of emotion processing are needed to better understand the pathophysiology of psychogenic nonepileptic seizures (PNES). We examined the differences in facial emotion processing between 12 patients with PNES, 12 patients with temporal lobe epilepsy (TLE), and 24 matched healthy controls (HCs) using fMRI with emotional faces task (EFT) (happy/sad/fearful/neutral) and resting state connectivity. Compared with TLE, patients with PNES exhibited increased fMRI response to happy, neutral, and fearful faces in visual, temporal, and/or parietal regions and decreased fMRI response to sad faces in the putamen bilaterally...
January 5, 2018: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29307332/an-overview-of-psychogenic-non-epileptic-seizures-etiology-diagnosis-and-management
#6
Ángela Milán-Tomás, Michelle Persyko, Martin Del Campo, Colin M Shapiro, Karl Farcnik
The purpose of this review is to provide an update of the research regarding the etiology, diagnosis and management of psychogenic non-epileptic seizures (PNES). A literature search using Pubmed, Ovid MEDLINE and EMBASE database was performed from 2000 up to August 2017. We have evaluated the different factors leading to PNES as well as the diagnostic approach and management of this disorder which continue to be very difficult. The coexistence of epilepsy and PNES poses special challenges and requires the coordinated efforts of the family physicians, psychiatrists, psychologists and neurologists...
January 8, 2018: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://www.readbyqxmd.com/read/29302825/tramadol-induced-hiccups-a-report-of-two-cases
#7
Radhika Panchal, Vishal Bhutt, Ashish Anovadiya, Bhargav Purohit, Firdaus Dekhaiya, Nutanbala Goswami
Hiccups can be idiopathic, psychogenic and organic, with drugs being one of the most important causes of hiccups. Although the exact pathophysiological processes involved are still poorly understood, the neurotransmitters dopamine, serotonin, and γ-aminobutyric acid (GABA) have been documented to play a significant role in the generation of hiccups. We report on two patients with cellulitis who developed hiccups with the use of tramadol as an analgesic. The possible mechanisms and clinical implications of this rare adverse event are discussed...
January 5, 2018: Drug Safety—Case Reports
https://www.readbyqxmd.com/read/29298187/evaluating-differential-effects-of-specific-pain-dismissal-interactions-with-physicians
#8
Amy C Lang, Eva C Igler, Ellen K Defenderfer, Julia Uihlein, Chasity T Brimeyer, W Hobart Davies
OBJECTIVES: Over 40% of adolescents with chronic pain report experiencing pain dismissal, which is a response from another individual that is perceived as diminishing, denying, or disbelieving an individual's report of pain. Pain dismissal by physicians often leaves patients feeling discredited, which may discourage them from seeking and receiving proper treatment for their pain. The purpose of this study was to investigate how the four most commonly reported types of physician pain dismissal differentially affect individuals' reactions...
January 2, 2018: Clinical Journal of Pain
https://www.readbyqxmd.com/read/29288631/gait-disorders
#9
REVIEW
Jessica M Baker
Walking is an extraordinarily complex task requiring integration of the entire nervous system, making gait susceptible to a variety of underlying neurological abnormalities. Gait disorders are particularly prevalent in the elderly and increase fall risk. In this review, we discuss an approach to the examination of gait, and highlight key features of common gait disorders and their underlying causes. We review gaits due to lesions of motor systems (spasticity and neuromuscular weakness), the cerebellum and sensory systems (ataxia), parkinsonism, and frontal lobes and discuss the remarkably diverse phenomenology of functional (psychogenic) gait disorders...
December 27, 2017: American Journal of Medicine
https://www.readbyqxmd.com/read/29285442/prevalence-and-etiological-profile-of-short-stature-among-school-children-in-a-south-indian-population
#10
Kumaravel Velayutham, S Sivan Arul Selvan, R V Jeyabalaji, S Balaji
Background and Objectives: Short stature (SS) is a common pediatric problem and it might be the first sign of underlying illness. Studies documenting the burden and etiological profile of SS are scarce from India and are mostly limited to data obtained from referral centers. Due to the lack of large-scale, community-based studies utilizing a standard protocol, the present study aimed to assess the prevalence and etiological profile of SS in school children of a South Indian district. Materials and Methods: In this cross-sectional study, children aged 4-16 years from 23 schools in Madurai district, Tamil Nadu, underwent anthropometric measurements and height was plotted in Khadilkar et al...
November 2017: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29282343/-diagnosis-of-psychogenic-non-epileptic-seizure-how-can-we-detect-it-prior-to-video-electroencephalography-monitoring
#11
Kousuke Kanemoto
It is highly recommended not to base the diagnosis of psychogenic non-epileptic seizures (PNES) on one single sign. Yet, the combination of several symptoms may be highly indicative of PNES. The aim of this paper is to demonstrate that some combinations of symptoms are more easily recorded and that some are more indicative of PNES. We review and analize various symptom combinations including convulsions, falling, and impaired consciousness. Further, we examine and discuss all individual symptoms that are known to be associated with PNES...
December 2017: Brain and Nerve, Shinkei Kenkyū No Shinpo
https://www.readbyqxmd.com/read/29282342/-motor-symptoms-of-autoimmune-encephalopathies
#12
Yuichi Tashiro, Hiroshi Takashima
Autoimmune encephalopathies are clinically and immunologically heterogeneous disorders. At least 20 types of autoimmune encephalopathies have been discovered, with the most common type being Hashimoto encephalopathy. In clinical situations, we often observe that patients with autoimmune encephalopathy are misdiagnosed because they exhibit signs similar to those observed in functional psychogenic movement, conversion, or somatoform disorders. We clinically examined over 100 patients with autoimmune encephalopathy...
December 2017: Brain and Nerve, Shinkei Kenkyū No Shinpo
https://www.readbyqxmd.com/read/29247701/adaptation-or-pathology-the-role-of-prenatal-stressor-type-and-intensity-in-the-developmental-programing-of-adult-phenotype
#13
REVIEW
Sophie St-Cyr, Patrick O McGowan
The mother is the major interface between the offspring and its prenatal environment. Prenatal toxins and stress-inducing physical agents are important factors programming the developmental trajectory of mammals that likely involve epigenetic modifications. However, prenatal stressors commonly-used in the laboratory (e.g. prenatal restraint stress and prenatal chronic variable stress) are typically administered at high intensities. These exposures typically lead to pathological phenotypes supporting the development origin of health and disease hypothesis...
December 13, 2017: Neurotoxicology and Teratology
https://www.readbyqxmd.com/read/29243122/aberrant-baseline-brain-activity-in-psychogenic-erectile-dysfunction-patients-a-resting-state-fmri-study
#14
Chenwang Jin, Min Guan, Minghao Dong, Jia Wu, Zhen He, Xin Chen, Dapeng Shi, Junchan Ren, Guangming Shi, Xiangsheng Zhang
Recent neuroimaging studies have elucidated many interesting and promising findings on sexuality regarding the neural underpinnings of both normal and abnormal sexual processes. Psychogenic erectile dysfunction (pED) consists of a major part of male sexual dysfunction in China, but the understanding of the central mechanism of pED is still in its infancy. It is commonly appreciated that pED is a functional disorder, which can be attributed predominantly or exclusively to psychological factors, such as anxiety, depression, loss of self-esteem, and psychosocial stresses...
December 14, 2017: Brain Imaging and Behavior
https://www.readbyqxmd.com/read/29241946/youth-with-psychogenic-non-syncopal-collapse-have-more-somatic-and-psychiatric-symptoms-and-lower-perceptions-of-peer-relationships-than-youth-with-syncope
#15
Geoffrey L Heyer
BACKGROUND: Little is known about somatic and psychiatric symptoms and perceived peer relationships of patients with psychogenic nonsyncopal collapse. OBJECTIVE: This study aimed to compare somatic and psychiatric symptoms and other elements potentially related to functional neurological symptom disorders between youth with psychogenic nonsyncopal collapse and those with neurally mediated syncope. METHODS: Before testing, patients completed a structured interview and questionnaire addressing current symptoms, previous psychiatric diagnoses, referrals, diagnostic testing, prescribed medications, and patient self-ratings of anxiety, depression, and perceived peer relationships...
November 20, 2017: Pediatric Neurology
https://www.readbyqxmd.com/read/29239801/psychogenic-nonepileptic-seizures-a-disconnect-between-body-and-mind
#16
EDITORIAL
Gholam K Motamedi
No abstract text is available yet for this article.
November 24, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29238670/specific-organ-targeted-vestibular-physiotherapy-the-pivot-in-the-contemporary-management-of-vertigo-and-imbalance
#17
EDITORIAL
Anirban Biswas, Bibhas Barui
Introduction: Advancements in our understanding of vestibular physiology and how it is changes in different diseases have established that of the three therapeutic approaches to treat disorders of the vestibular system viz. pharmacotherapy, surgery and physical therapy, it is the later i.e., physical therapy which is the most efficacious modality in the management of balance disorders. The futility of vestibular sedatives in the correction of vestibular disorders and in the restoration of balance and the very limited role of surgery has now been recognised...
December 2017: Indian Journal of Otolaryngology and Head and Neck Surgery
https://www.readbyqxmd.com/read/29227256/-psychogenic-factors-in-the-pathogenesis-of-anterior-ischemic-optic-neuropathy-review
#18
B Ahmadyarova, Y Shusterov, M Lyubchenko
The purpose of this systematic review is to describe the influence of psychogenic factors on the pathogenesis and course of anterior ischemic optic neuropathy (AION). Analysis of randomized clinical trials published in the journal indexed in PubMed in the period from 1978 to 2016, devoted to the study of the influence of various factors on the epidemiology, pathogenesis and course of AION. The review of the literature presents basic information on the psychogenic factors that affect the course of AION and the areas of clinical application of the data under study...
November 2017: Georgian Medical News
https://www.readbyqxmd.com/read/29220065/clinical-profile-of-patients-with-psychogenic-non-epileptic-seizures-in-puerto-rico
#19
Joashlie M Méndez-Ruiz, Alfonso Martínez-Taboas, Yeira M Valdez-Pimentel, Miguel Torres-Narváez, Marianette Colón-Laboy, Gisela G Jiménez-Colón, José Rodríguez-Gómez, Christian J González-Jiménez
OBJECTIVE: Specialized epilepsy clinics receive many cases (20%-30% of total cases) in which the patients are diagnosed with psychogenic non-epileptic seizures (PNES). In Puerto Rico, there has been a lack of research on and data about patients with PNES. This study examined the clinical profile of 34 patients with a confirmed diagnosis of PNES. METHODS: A secondary analysis of 34 clinical records of patients with PNES was conducted. The resulting profile was based on clinical interviews, the behavioral presentation of seizures, the history of traumatic experiences or abuse, and the relationship between PNES events and life stressors...
December 2017: Puerto Rico Health Sciences Journal
https://www.readbyqxmd.com/read/29218816/long-term-adherence-with-psychiatric-treatment-among-patients-with-psychogenic-nonepileptic-seizures
#20
Benjamin Tolchin, Barbara A Dworetzky, Gaston Baslet
We conducted a prospective cohort study, examining long-term adherence with psychiatric treatment among patients with psychogenic nonepileptic seizures (PNES). Subjects diagnosed with documented PNES were scheduled for 4 psychiatric visits. Survival analysis was performed, and covariates were assessed for association with time to nonadherence using Cox proportional hazard regression analysis. One hundred twenty-three subjects were recruited and followed for up to 17 months. Eighty percent of subjects attended the first outpatient visit, 42% attended the second, 24% attended the third, and only 14% remained adherent through the fourth visit...
December 7, 2017: Epilepsia
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