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https://www.readbyqxmd.com/read/29145409/predictors-of-suicide-ideation-among-older-adults-with-bipolar-disorder
#1
Norm O'Rourke, Marnin J Heisel, Sarah L Canham, Andrew Sixsmith
OBJECTIVES: Bipolar disorder (BD) carries the greatest risk of death by suicide of all psychiatric conditions as 25%-50% of those with BD will make one or more suicide attempt, and about 15% will intentionally end their lives. Among young adults with BD, substance misuse, medication non-adherence, age at onset, and comorbid psychiatric conditions each predict self-harm. It is currently unclear if these same factors or others predict suicide ideation among older adults with BD. METHODS: We recruited a global sample of 220 older adults with BD over 19 days using socio-demographically targeted, social media advertising and online data collection (Mean = 58...
2017: PloS One
https://www.readbyqxmd.com/read/29145269/multimodal-ultrasonographic-assessment-of-leiomyosarcoma-of-the-femoral-vein-in-a-patient-misdiagnosed-as-having-deep-vein-thrombosis-a-case-report
#2
Mei Zhang, Feng Yan, Bin Huang, Zhoupeng Wu, Xiaorong Wen
RATIONALE: Primary leiomyosarcoma (LMS) of the vein is a rare tumor that arises from the smooth muscle cells of the vessel wall and has an extremely poor prognosis. This tumor can occur in vessels such as the inferior vena cava, great saphenous vein, femoral vein, iliac vein, popliteal vein, and renal vein; the inferior vena cava is the most common site. LMS of the femoral vein can result in edema and pain in the lower extremity; therefore, it is not easy to be differentiated from deep vein thrombosis (DVT)...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29145136/lead-cadmium-and-arsenic-in-human-milk-and-their-socio-demographic-and-lifestyle-determinants-in-lebanon
#3
Maya Bassil, Farah Daou, Hussein Hassan, Osama Yamani, Joelle Abi Kharma, Zouheir Attieh, Jomana Elaridi
INTRODUCTION: Exposure of newborns to toxic metals is of special interest due to their reported contamination in breast milk and potential harm. The aim of this study was to assess the occurrence and factors associated with lead, cadmium and arsenic contamination in breast milk collected from lactating mothers in Lebanon. METHODS: A total of 74 breast milk samples were collected from primaparas according to guidelines set by the World Health Organization. A survey was administered to determine the demographic and anthropometric characteristics of participating lactating mothers...
October 27, 2017: Chemosphere
https://www.readbyqxmd.com/read/29145090/comparative-study-of-dissolved-organic-matter-generated-from-activated-sludge-during-exposure-to-hypochlorite-hydrogen-peroxide-acid-and-alkaline-implications-for-on-line-chemical-cleaning-of-mbr
#4
Weiwei Cai, Yu Liu
Although on-line chemical cleaning has been extensively employed for maintaining the MBR permeability, little attention has been given to the negative impacts of such prevalent membrane cleaning practice. This study thus comparatively investigated the potential release of dissolved organic matter (DOM) from activated sludge upon the exposure to different kinds of frequently-used cleaning reagents, i.e. NaClO, H2O2, HCl and NaOH. It was found that NaClO at 50 and 80 mg L(-1) triggered significant release of DOM, while NaOH strongly promoted soluble nitrogen release...
November 8, 2017: Chemosphere
https://www.readbyqxmd.com/read/29145087/retention-performance-of-three-widely-used-spe-sorbents-for-the-extraction-of-perfluoroalkyl-substances-from-seawater
#5
Miroslav Brumovský, Jitka Bečanová, Pavlína Karásková, Luca Nizzetto
Some per- and polyfluoroalkyl substances (PFASs) have been detected ubiquitously in the environment. Owing to the polar character conferred by the presence of the carboxylic or sulfonic acid groups and their resistance to degradation, aquatic environments became their major reservoirs, including marine waters. The procedure of PFAS analysis in aqueous matrices consists usually of solid-phase extraction (SPE) followed by high-performance liquid chromatography coupled to tandem mass spectrometry. Moreover, passive sampling approach using various SPE sorbents may be applied...
November 7, 2017: Chemosphere
https://www.readbyqxmd.com/read/29144857/a-review-of-tribal-best-practices-in-substance-abuse-prevention
#6
Allyson Kelley, Morgan Witzel, Bethany Fatupaito
American Indian youth experience higher rates of substance use than non-American Indian youth. Researchers, clinicians, and treatment programs embrace evidence-based practices (EBPs) and practice based evidence (PBE) as a primary method for addressing substance abuse and advancing behavioral health. However, less is known about the use of tribal best practices (TBPs) and how they are implemented in American Indian substance use prevention contexts. OBJECTIVE: The main objective of this systematic review was to determine how TBPs are implemented and shared in the context of tribal substance use prevention...
November 16, 2017: Journal of Ethnicity in Substance Abuse
https://www.readbyqxmd.com/read/29144294/higher-alkyl-sulfatase-activity-required-by-microbial-inhabitants-to-remove-anionic-surfactants-in-the-contaminated-surface-waters
#7
Bulent Icgen, Salih Batuhan Salik, Lale Goksu, Huseyin Ulusoy, Fadime Yilmaz
Biodegradation of anionic surfactants, like sodium dodecyl sulfate (SDS) are challenged by some bacteria through the function of the enzyme alkyl sulfatases. Therefore, identifying and characterizing bacteria capable of degrading SDS with high alkyl sulfatase enzyme activity are pivotal. In this study, bacteria isolated from surfactant contaminated river water were screened for their potential to degrade SDS. Primary screening carried out by the conventional enrichment culture technique and assessment of SDS-degrading ability through methylene blue active substance assay revealed 12, out of 290, SDS-degrading surface water bacteria with maximum SDS degrading abilities of 46-94% in 24-54 h...
November 2017: Water Science and Technology: a Journal of the International Association on Water Pollution Research
https://www.readbyqxmd.com/read/29144287/assessment-of-a-danish-sludge-treatment-reed-bed-system-and-a-stockpile-area-using-substance-flow-analysis
#8
Julie D Larsen, Steen M Nielsen, Charlotte Scheutz
Sludge treatment reed bed (STRB) systems combine dewatering, stabilisation and long-term storage of sludge. The main objective of this study was to investigate how substance concentrations change in the sludge residue during treatment and to conduct substance flow analyses covering the flow of substances in an STRB system over a 12-year treatment period, followed by three months' post-treatment in a stockpile area (SPA). Samples of sludge, reject water and sludge residue of different ages were collected at two Danish STRB system facilities and analysed for content of relevant substances...
November 2017: Water Science and Technology: a Journal of the International Association on Water Pollution Research
https://www.readbyqxmd.com/read/29144148/a-prospective-study-of-mutual-influence-for-substance-use-among-young-adult-marital-dyads
#9
Michael Windle, Rebecca C Windle
The purpose of this 2-wave longitudinal study was to specify, test, and evaluate an actor-partner interdependence model (APIM) with young adult marital dyads to test husbands' and wives' mutual influences on each other's substance use. Prospective data were collected from young adults and their spouses at baseline and 5 years later. Data from 237 dyads were used to test spouses' interdependence on alcohol use, alcohol problems, and marijuana use with the APIMs. Marital partners had significant effects on each other's substance use, though the patterns were different contingent on the outcome referenced...
November 16, 2017: Psychology of Addictive Behaviors: Journal of the Society of Psychologists in Addictive Behaviors
https://www.readbyqxmd.com/read/29144146/legalization-of-recreational-marijuana-and-community-sales-policy-in-oregon-impact-on-adolescent-willingness-and-intent-to-use-parent-use-and-adolescent-use
#10
Julie C Rusby, Erika Westling, Ryann Crowley, John M Light
Studies investigating the impact of medical marijuana legalization have found no significant changes in adolescent use. In one of the few studies focused on recreational marijuana, we investigated how recreational marijuana legalization and community sales policy influenced factors that likely impact youth use (youth willingness and intent to use, parent use) as well as youth use. Legalization of recreational marijuana in Oregon coincided with our study on adolescent substance use. Cohort 1 transitioned from 8th to 9th grade prior to legalization and Cohort 2 made this transition during legalization (N = 444; 53% female)...
November 16, 2017: Psychology of Addictive Behaviors: Journal of the Society of Psychologists in Addictive Behaviors
https://www.readbyqxmd.com/read/29143853/sex-specific-risk-assessment-of-pfhxs-using-a-physiologically-based-pharmacokinetic-model
#11
Sook-Jin Kim, Hwajin Shin, Yong-Bok Lee, Hea-Young Cho
Perfluorohexanesulfonate (PFHxS), which belongs to the group of perfluoroalkyl and polyfluoroalkyl substances (PFASs), has been extensively used in industry and subsequently detected in the environment. Its use may be problematic, as PFHxS is known to induce neuronal cell death, and has been associated with early onset menopause in women and with attention deficit/hyperactivity disorder. Due to these impending issues, the aim of this study is to develop and evaluate a physiologically based pharmacokinetic (PBPK) model for PFHxS in male and female rats, and apply this to a human health risk assessment...
November 16, 2017: Archives of Toxicology
https://www.readbyqxmd.com/read/29143843/mitochondria-targetable-carbon-quantum-dots-for-differentiating-cancerous-cells-from-normal-cells
#12
Ge Gao, Yao-Wen Jiang, Jingjing Yang, Fu-Gen Wu
In this study, a series of fluorescent carbon quantum dots (or carbon dots, CDs) with inherent mitochondrial targeting/imaging and cancerous/normal cell differentiation capabilities were prepared by a one-pot solvothermal treatment of glycerol and a silane molecule. Glycerol acted as a solvent and carbon source, and the silane molecule acted as a passivation agent. The as-prepared CDs could specifically and stably (for at least 24 h) visualize mitochondria of various types of cells without the introduction of mitochondria-targeting ligands (such as triphenylphosphonium)...
November 16, 2017: Nanoscale
https://www.readbyqxmd.com/read/29143694/cryo-scanning-electron-microscopy-sem-and-scanning-transmission-electron-microscopy-stem-in-sem-for-bio-and-organo-mineral-interface-characterization-in-the-environment
#13
Guillaume Wille, Jennifer Hellal, Patrick Ollivier, Annie Richard, Agnes Burel, Louis Jolly, Marc Crampon, Caroline Michel
Understanding biofilm interactions with surrounding substratum and pollutants/particles can benefit from the application of existing microscopy tools. Using the example of biofilm interactions with zero-valent iron nanoparticles (nZVI), this study aims to apply various approaches in biofilm preparation and labeling for fluorescent or electron microscopy and energy dispersive X-ray spectrometry (EDS) microanalysis for accurate observations. According to the targeted microscopy method, biofilms were sampled as flocs or attached biofilm, submitted to labeling using 4',6-diamidino-2-phenylindol, lectins PNA and ConA coupled to fluorescent dye or gold nanoparticles, and prepared for observation (fixation, cross-section, freezing, ultramicrotomy)...
November 16, 2017: Microscopy and Microanalysis
https://www.readbyqxmd.com/read/29143575/determination-of-illegal-adulteration-of-dietary-supplements-with-synthetic-hair-growth-compounds-by-uplc-and-lc-q-tof-ms
#14
Ji Hyun Lee, Gihaeng Kang, Han Na Park, Jihee Kim, Nam Sook Kim, Seongsoo Park, Sung-Kwan Park, Sun Young Baek, Hoil Kang
In this study, we developed a UPLC-PDA and LC-Q-TOF/MS method to identify and measure the following prohibited substances that may be found in dietary supplements: triaminodil, minoxidil, bimatoprost, alimemazine, diphenylcyclopropenone, α-tradiol, finasteride, methyltestosterone, spironolatone, flutamide, cyproterone, dutasteride, and testosterone 17-propionate.The method was validated according to International Conference on Harmonization guidelines in terms of specificity, linearity, accuracy, precision, LOD, LOQ, recovery, and stability...
November 16, 2017: Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
https://www.readbyqxmd.com/read/29143486/violent-behaviour-in-early-psychosis-patients-can-we-identify-clinical-risk-profiles
#15
Valerie Moulin, Julie Palix, Philippe Golay, Alexandre Dumais, Mohammad Mehdi Gholamrezaee, Agathe Azzola, Philipp S Baumann, Luis Alameda, Philippe Conus
AIMS: The objective of this study is to explore, within a sample of early psychosis patients (EPP), if subgroups regarding rate of violent behaviour (VB) against others can be identified on the basis of dynamic risk factors (treatment modifiable characteristics). METHODS: In a sample of 265 EPP, treated at the Treatment and Early Intervention in Psychosis Program in Lausanne, we conducted a latent-class analysis on the basis of the main dynamic VB risk factors (substance use disorder [SUD], positive symptoms, insight, and impulsivity)...
November 15, 2017: Early Intervention in Psychiatry
https://www.readbyqxmd.com/read/29143367/risk-of-death-associated-with-new-benzodiazepine-use-among-persons-with-alzheimer-disease-a-matched-cohort-study
#16
Laura Saarelainen, Anna-Maija Tolppanen, Marjaana Koponen, Antti Tanskanen, Jari Tiihonen, Sirpa Hartikainen, Heidi Taipale
OBJECTIVE: To investigate the risk of death associated with new benzodiazepine and related drug (BZDR) use in a nationwide cohort of persons with Alzheimer disease (AD). METHODS: The register-based MEDALZ cohort, including all community-dwelling Finns diagnosed with AD during 2005 to 2011 (n = 70 718), was used. Clinically verified AD diagnoses were obtained from the Special Reimbursement Register. Drug use periods were modeled from BZDR purchases, derived from the Prescription Register...
November 15, 2017: International Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/29143257/environmental-characteristics-and-changes-of-sediment-pore-water-dissolved-organic-matter-in-four-chinese-lakes
#17
Khan M G Mostofa, Wen Li, Fengchang Wu, Cong-Qiang Liu, Haiqing Liao, Li Zeng, Min Xiao
Sediment pore waters were examined in four Chinese lakes (Bosten, Qinghai, Chenghai and Dianchi) to characterise the sources of dissolved organic matter (DOM) and their microbial changes in the sediment depth profiles. Parallel factor (PARAFAC) modelling on the sample fluorescence spectra confirmed that the pore water DOM was mostly composed of two components with a mixture of both allochthonous and autochthonous fulvic acid-like substances in three lakes, except Lake Dianchi, and protein-like components in Lake Bosten...
November 15, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29143095/areca-nut-chewing-is-associated-with-common-mental-disorders-a-population-based-study
#18
Tzu-Yu Lin, Huan-Cheng Chang, Kuang-Hung Hsu
INTRODUCTION: Forms of habitual substance use including cigarette smoking and alcohol consumption have been documented as risk factors of common mental disorders (CMDs). The effects of areca nut chewing on biophysiological tests, metabolic syndromes, and liver function have been reported previously; however, the relationship between areca nut chewing and CMDs remains unclear. This study examined the association between areca nut chewing and CMDs and explored the relationships between areca nut chewing and biophysiological indicators...
November 15, 2017: Social Psychiatry and Psychiatric Epidemiology
https://www.readbyqxmd.com/read/29142605/aviscumine-a-recombinant-ribosomal-inhibitor-increases-the-antitumor-activity-of-natural-killer-cells
#19
Gabriele Gamerith, Arno Amann, Bettina Schenk, Thomas Auer, Hans Lentzen, Dirk O Mügge, Katharina M Cima, Judith Löffler-Ragg, Wolfgang Hilbe, Heinz Zwierzina
Aviscumine, a recombinant lectin I, has been identified as an immunomodulatory agent within a new class of ribotoxic stress-inducing anticancer substances that have demonstrated efficacy in phase I/II trials. The aim of the present study was to elucidate the presumed effect of aviscumine on enhancing human natural killer (NK) cell antitumor cytotoxicity. To measure the effect of aviscumine on human NK cell cytotoxicity, chromium-51-release assays against K-562 cells were performed with isolated NK cells from the whole blood of 34 healthy volunteers...
November 2017: Oncology Letters
https://www.readbyqxmd.com/read/29142474/clinical-features-of-alcoholic-hepatitis-in-latinos-and-caucasians-a-single-center-experience
#20
Rogelio Pinon-Gutierrez, Blythe Durbin-Johnson, Charles H Halsted, Valentina Medici
AIM: To study differences of presentation, management, and prognosis of alcoholic hepatitis in Latinos compared to Caucasians. METHODS: We retrospectively screened 876 charts of Caucasian and Latino patients who were evaluated at University of California Davis Medical Center between 1/1/2002-12/31/2014 with the diagnosis of alcoholic liver disease. We identified and collected data on 137 Caucasians and 64 Latinos who met criteria for alcoholic hepatitis, including chronic history of heavy alcohol use, at least one episode of jaundice with bilirubin ≥ 3...
October 28, 2017: World Journal of Gastroenterology: WJG
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