keyword
https://read.qxmd.com/read/36258747/translation-linguistic-validation-and-readability-of-the-spanish-version-of-the-visa-h-scale-in-elite-athletes
#21
JOURNAL ARTICLE
Ivan Medina-Porqueres, Daniel Rosado Velazquez, Francisco Moya Torrecilla
Background: Data regarding the diagnosis of Proximal Hamstring Tendinopathy (PHT) is limited. There is a need for a standardized, valid, and reliable instrument for evaluating PHT among Spanish population. The purpose of this study was to linguistically validate and cross-culturally adapt the Spanish version of the VISA-H for Spanish population and to assess its readability, initial feasibility, appropriateness and acceptability. Methods: Cross-cultural adaptation was done according to established guidelines...
August 2022: Archives of Bone and Joint Surgery
https://read.qxmd.com/read/35916474/single-cell-multi-omics-characterise-discrete-human-tendon-cells-populations-that-persist-in-vitro-and-on-fibrous-scaffolds
#22
JOURNAL ARTICLE
A Gomez-Collignon, R Brown, A Carr, S Dakin, A Lach, C Loizou, M Rogers, R Sharp, A Kendal
Chronic tendinopathy represents a growing healthcare burden in the ageing global population. Curative therapies remain elusive as the mechanisms that underlie chronic inflammation in tendon disease remain unclear. Identifying and isolating key pathogenic and reparative cells is essential in developing precision therapies and implantable materials for improved tendon healing. Multiple discrete human tendon cell populations have been previously described ex vivo. To determine if these populations persist in vitro, healthy human hamstring tenocytes were cultured for 8 d on either tissue culture plastic or aligned electrospun fibres of absorbable polydioxanone...
August 2, 2022: European Cells & Materials
https://read.qxmd.com/read/35862638/evaluation-of-ss-31-as-a-potential-strategy-for-tendinopathy-treatment-an-in-vitro-model
#23
JOURNAL ARTICLE
Xueying Zhang, Ying Zhang, Meng Zhang, Yusuke Nakagawa, Camila B Caballo, Hazel H Szeto, Xiang-Hua Deng, Scott A Rodeo
BACKGROUND: Studies in our laboratory have demonstrated mitochondrial dysfunction in human and animal models of supraspinatus tendinopathy. SS-31 (elamipretide) has been reported to improve mitochondrial function and to be effective in clinical trials for several diseases. The potential of SS-31 in treating tendinopathy has not been explored. HYPOTHESIS: SS-31 would improve mitochondrial function in human tenocytes sampled from patients with tendinopathy. STUDY DESIGN: Controlled laboratory study...
August 2022: American Journal of Sports Medicine
https://read.qxmd.com/read/35846572/amelioration-of-experimental-tendinopathy-by-lentiviral-cd44-gene-therapy-targeting-senescence-associated-secretory-phenotypes
#24
JOURNAL ARTICLE
Shih-Yao Chen, I-Ming Jou, Po-Yen Ko, Kai-Lan Hsu, Wei-Ren Su, Li-Chieh Kuo, Pei-Yuan Lee, Chao-Liang Wu, Po-Ting Wu
CD44 exerts anti-senescence effects in many disease models. We examined senescence in tendinopathy and the effect of CD44 on senescence-associated secretory phenotypes (SASPs). Senescent markers were determined in human tendinopathic long head of bicep (LHB) and normal hamstring tendons. CD44 gene transfer in rat tendinopathic tenocytes stimulated with interleukin (IL)-1β and a rat Achilles tendinopathy model were performed using lentiviral vectors. Expression levels of p53, p21, and p16 and senescence-associated β-galactosidase (SA-β-gal) activity were positively correlated with the severity of human tendinopathy and were higher in rat and human tendinopathic tenocytes than in normal controls...
September 8, 2022: Molecular Therapy. Methods & Clinical Development
https://read.qxmd.com/read/35666137/celecoxib-beyond-anti-inflammation-alleviates-tendon-derived-stem-cell-senescence-in-degenerative-rotator-cuff-tendinopathy
#25
JOURNAL ARTICLE
Zhuochang Cai, Yao Zhang, Shen Liu, Xudong Liu
BACKGROUND: Degenerative rotator cuff tendinopathy (RCT) is associated with the senescence of tendon-derived stem cells (TDSCs). Nonsteroidal anti-inflammatory drugs have been demonstrated to alleviate age-associated inflammation (inflamm-aging)-induced cellular senescence of skeletal stem/progenitor cells. However, whether they can alleviate degenerative RCT through reducing inflamm-aging-related TDSC senescence is still unknown. PURPOSE: To assess whether celecoxib can prevent the inflamm-aging-related cellular senescence of TDSCs...
July 2022: American Journal of Sports Medicine
https://read.qxmd.com/read/35647184/effectiveness-of-high-power-laser-therapy-on-pain-and-isokinetic-peak-torque-in-athletes-with-proximal-hamstring-tendinopathy-a-randomized-trial
#26
RANDOMIZED CONTROLLED TRIAL
Sachin Verma, Vandana Esht, Aksh Chahal, Gaurav Kapoor, Sorabh Sharma, Ahmad H Alghadir, Masood Khan, Faizan Z Kashoo, Mohammad A Shaphe
Athletes such as long-distance runners, sprinters, hockey, and/or football players may have proximal hamstring tendinopathy (PHT). Laser therapy has been shown to be effective in tendinopathies. High power laser therapy (HPLT) is used for the treatment of several musculoskeletal conditions; however, its efficacy on PHT has not been investigated. This study is aimed at examining the effects of HPLT on pain and isokinetic peak torque (IPT) in athletes with PHT. The two-arm comparative pretest-posttest experimental design was used with random allocation of 36 athletes aged 18-35 years into two groups (experimental and conventional group)...
2022: BioMed Research International
https://read.qxmd.com/read/35591280/consequences-of-patellar-tendinopathy-on-isokinetic-knee-strength-and-jumps-in-professional-volleyball-players
#27
JOURNAL ARTICLE
Marie Chantrelle, Pierre Menu, Marie Gernigon, Bastien Louguet, Marc Dauty, Alban Fouasson-Chailloux
Patellar tendinopathy (PT) in professional volleyball players can have an impact on their careers. We evaluated the impact of this pathology in this specific population in terms of isokinetic strength and jumping performances. Thirty-six professional male volleyball players (mean age: 24.8 ± 5.2) performed isokinetic knee assessments, single-leg countermovement jumps and one leg hop test. They filled out the Victorian Institute of Sport Assessment-Patella (VISA-P) score. Two groups were assessed: "PT group" ( n = 15) and "control group" ( n = 21)...
May 9, 2022: Sensors
https://read.qxmd.com/read/35391874/injury-and-illness-in-elite-athletics-a-prospective-cohort-study-over-three-seasons
#28
JOURNAL ARTICLE
Shane Kelly, Noel Pollock, George Polglass, Ben Clarsen
BACKGROUND: Athletics (also known as track and field) is one of the most popular sports in the world and is the centrepiece of the Summer Olympic Games. Participation in athletics training and competition involves a risk of illness and injury. PURPOSE: To describe injury and illness in British Olympic track and field athletes over three full training and competition seasons. STUDY DESIGN: Descriptive Epidemiology Study. METHODS: A total of 111 athletes on the British national program were followed prospectively for three consecutive seasons between 2015-2018...
2022: International Journal of Sports Physical Therapy
https://read.qxmd.com/read/35377311/treatment-of-chronic-proximal-hamstring-tendinopathy-with-surgical-debridement-and-suture-anchor-repair
#29
JOURNAL ARTICLE
Sean Fitzpatrick, Robert A Magnussen, Benjamin Léger-St-Jean, Zylyftar Gorica, W Kelton Vasileff, Christopher C Kaeding
We evaluated outcomes following surgical debridement and suture anchor repair of chronic proximal hamstring tendinopathy without sciatic nerve decompression. Chart review identified eight patients (one bilateral) who met study requirements. All eight patients were available for follow-up at a mean of 6.7 years and none underwent re-operation on the index hip during the follow-up period. Seven patients completed patient-reported outcome scores. The mean LEFS score was 81.1, and the mean SANE score was 74.9. The mean Marx activity score was 2...
2022: Journal of Surgical Orthopaedic Advances
https://read.qxmd.com/read/35114504/the-brazilian-version-of-the-victorian-institute-of-sport-assessment-hamstring-visa-h-questionnaire-translation-cross-cultural-adaptation-and-measurement-properties
#30
JOURNAL ARTICLE
Pedro Olavo de Paula Lima, Bianca Martins Lourenco, Lucas Valentim de Freitas, Thamiris Silva Nazareno, Nicola Maffulli, Rodrigo Ribeiro de Oliveira
STUDY DESIGN: Study of diagnostic accuracy/assessment scale. BACKGROUND: Proximal hamstring tendinopathy (PHT) usually causes disability, deep pain in the proximal insertion of the tendon, and limitations in daily life and sports practice. Scales that assess PHT pain and disability may assist practitioners in their clinical decision-making processes. OBJECTIVES: To perform a translation, cross-cultural adaptation and to evaluate the measurement properties of the Victorian Institute of Sport Assessment - Hamstring (VISA-H) questionnaire for the Brazilian population...
January 31, 2022: Musculoskeletal Science & Practice
https://read.qxmd.com/read/34740402/proximal-hamstring-tears-endoscopic-hamstring-repair
#31
JOURNAL ARTICLE
William Arroyo, Carlos A Guanche
Proximal hamstring tears are common among athletes, especially in sports involving eccentric lengthening during forced hip flexion and knee extension, such as hurdles or water skiing. Tears are described by timing (acute [<1 month] or chronic) and severity (partial or complete). Complete tears are easily identified with magnetic resonance imaging; however, partial tears may be subtle and potentially missed. The spectrum of pathology associated with acute injuries ranges from minor strains to complete tears or avulsions...
November 2021: Arthroscopy
https://read.qxmd.com/read/34567595/the-use-of-biologics-to-improve-patient-reported-outcomes-in-hip-preservation
#32
REVIEW
Spencer W Sullivan, Oluwatobi M Aladesuru, Anil S Ranawat, Benedict U Nwachukwu
Despite lack of clear understanding, the use of biologic treatment methods has increased in the United States. Therapeutic methods, including platelet-rich plasma (PRP), bone marrow aspirate concentrate (BMAC) and hyaluronic acid (HA) among other biologics, are commonly associated with relief of pain in a number of different orthopedic conditions. Within the past two decades, hip preservationists have investigated the roles of these biologic treatments in both non-operative and surgical management of common hip conditions...
January 2021: Journal of Hip Preservation Surgery
https://read.qxmd.com/read/34481615/platelet-rich-plasma-fundamentals-and-clinical-applications
#33
JOURNAL ARTICLE
Andrew J Sheean, Adam W Anz, James P Bradley
Platelet-rich plasma (PRP) is perhaps the most widely studied of the biologic therapies, with an ever-growing body of evidence supporting its safety and efficacy in decreasing inflammation and pain and promoting healing in the setting of both nonoperative and operative treatments. PRP is produced by the centrifugation of whole blood, isolating its constituent parts based on their unique densities. These density gradients can be selectively harvested so as to obtain different concentrations of various blood product components, such as platelets and leukocytes...
September 2021: Arthroscopy
https://read.qxmd.com/read/34435068/tendon-derived-progenitor-cells-with-multilineage-potential-are-present-within-human-patellar-tendon
#34
JOURNAL ARTICLE
Erika A Leonardi, Michelle Xiao, Iain R Murray, William H Robinson, Geoffrey D Abrams
Background: Progenitor cells serve as a promising source of regenerative potential in a variety of tissue types yet remain underutilized in tendinopathy. Tendon-derived progenitor cells (TDPCs) have previously been isolated from hamstring tendon but only as part of a concomitant medical procedure. Determining the presence of TDPCs in patellar tendon may facilitate clinical utilization of these cells because of the relative accessibility of this location for tissue harvest. Purpose: To characterize TDPCs in human patellar tendon samples...
August 2021: Orthopaedic Journal of Sports Medicine
https://read.qxmd.com/read/34419731/mr-of-tendons-about-the-hip-a-study-in-asymptomatic-volunteers
#35
JOURNAL ARTICLE
Veerle De Grove, Nico Buls, Frederik Vandenbroucke, Maryam Shahabpour, Aldo Scafoglieri, Johan de Mey, Michel De Maeseneer
PURPOSE: Tendon pathology around the hip is a common entity. The aim of this study was to detect tendon abnormalities around the hip in a population of asymptomatic volunteers. MATERIALS AND METHODS: Fifty volunteers (100 hips) referred for non-musculoskeletal conditions were evaluated with an additional coronal STIR-weighted MRI imaging on a 1.5 MR unit. This group was composed of 27 women and 23 men with a mean age of 52 (19-91 years). The images were interpreted independently by 2 musculoskeletal radiologists...
October 2021: European Journal of Radiology
https://read.qxmd.com/read/34277189/bioinductive-collagen-implant-augmentation-for-the-repair-of-chronic-lower-extremity-tendinopathies-a-report-of-two-cases
#36
Austin M Looney, Luc M Fortier, Joseph D Leider, Brandon J Bryant
In this report, we present two cases of refractory chronic lower extremity tendinopathies treated with collagen bioinductive implant augmentation: a 20-year-old male football player with chronic patellar tendinopathy and a 40-year-old active female with chronic proximal hamstring tendinopathy. We demonstrate that bioaugmentation may represent an effective strategy in the surgical treatment of chronic tendinopathies. Both patients were able to return to their pre-injury activity levels at an accelerated rate...
June 2021: Curēus
https://read.qxmd.com/read/34229132/cross-cultural-adaptation-of-the-victorian-institute-of-sports-assessment-hamstrings-visa-h-questionnaire-for-spanish-speaking-athletes-with-proximal-hamstring-tendinopathy
#37
JOURNAL ARTICLE
Blanca De-la-Cruz-Torres, Nicola Maffulli, Sergio Hernández-Sánchez
OBJECTIVE: To cross-culturally adapt and validate the Victorian Institute of Sports Assessment - Hamstrings (VISA-H) scale into Spanish. DESIGN: Clinical measurement study (psychometric analysis). SETTING: Sports clubs and physiotherapy clinics. PARTICIPANTS: The Spanish version of the VISA-H (VISA-H-Sp) scale was administered to 101 subjects: 50 healthy runners and 51 patients with a clinical diagnosis of PHT. MAIN MEASURES: The Victorian Institute of Sports Assessment - Hamstrings...
September 2021: Physical Therapy in Sport
https://read.qxmd.com/read/34218525/distal-semimembranosus-tendinopathy-a-narrative-review
#38
REVIEW
Mark Sederberg, Laura LaMarche, Lee Skinner, Daniel M Cushman
Distal semimembranosus tendinopathy is a relatively uncommon diagnosis that can be responsible for medial knee pain. The semimembranosus tendon inserts on the posteromedial knee and is surrounded by the semimembranosus bursa, with both the bursa and tendon potential sources of pain. Similar to other tendinopathies, semimembranosus tendinopathy often occurs with overuse of the musculotendinous unit and is commonly seen in runners. Diagnosis can be made clinically and may be substantiated with use of ultrasound or magnetic resonance imaging...
August 2022: PM & R: the Journal of Injury, Function, and Rehabilitation
https://read.qxmd.com/read/34206269/impact-of-patellar-tendinopathy-on-isokinetic-knee-strength-and-jumps-in-professional-basketball-players
#39
JOURNAL ARTICLE
Marc Dauty, Pierre Menu, Olivier Mesland, Bastien Louguet, Alban Fouasson-Chailloux
Patellar tendinopathy is characterized by tendon pain which may reduce the level of performance. This study's main aim was to compare isokinetic knee strength and jump performances at the start of the sport season between players with patellar tendinopathy and those without. Secondary aims were to assess the relationship between knee strength and jump function. Sixty-two professional basketball players were enrolled (mean age: 25.0 ± 4.0). All players performed knee isokinetic measurements, single leg countermovement jumps, and one leg hop tests...
June 22, 2021: Sensors
https://read.qxmd.com/read/34109840/clinical-and-patient-reported-outcomes-following-peroneus-brevis-reconstruction-with-hamstring-tendon-autograft
#40
JOURNAL ARTICLE
Bopha Chrea, Stephanie K Eble, Jonathan Day, Oliver B Hansen, Scott J Ellis, Martin J O'Malley, Mark C Drakos
BACKGROUND: Peroneal tendon injuries are a common cause of lateral ankle pain and instability. While the use of hamstring autograft has been proposed as a viable surgical option for peroneus brevis reconstruction, reported outcomes with this technique are limited in the literature. We present patient-reported and clinical outcomes for patients who underwent peroneus brevis reconstruction with hamstring autograft. METHODS: Thirty-one patients were retrospectively identified who underwent a procedure including peroneus brevis reconstruction with hamstring autograft for peroneal tendinopathy between February 2016 and May 2019...
November 2021: Foot & Ankle International
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