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https://www.readbyqxmd.com/read/29147994/printability-of-papers-recycled-from-toner-and-inkjet-printed-papers-after-deinking-and-recycling-processes
#1
Arif Karademir, Cem Aydemir, Dogan Tutak, Raja Aravamuthan
BACKGROUND: In our contemporary world, while part of the fibers used in the paper industry is obtained from primary fibers such as wood and agricultural plants, the rest is obtained from secondary fibers from waste papers. To manufacture paper with high optical quality from fibers of recycled waste papers, these papers require deinking and bleaching of fibers at desired levels. High efficiency in removal of ink from paper mass during recycling, and hence deinkability, are especially crucial for the optical and printability quality of the ultimate manufactured paper...
November 11, 2017: Journal of Applied Biomaterials & Functional Materials
https://www.readbyqxmd.com/read/29145169/a-zinc-schiff-base-complex-inhibits-cancer-progression-both-in-vivo-and-in-vitro-by-inducing-apoptosis
#2
Arpita Banerjee, Kaushik Banerjee, Abhinaba Sinha, Satyajit Das, Saikat Majumder, Subrata Majumdar, Soumitra Kumar Choudhuri
Cancer chemotherapy suffers from selectivity and undesired toxicity of the drugs. Since zinc is a biocompatible tracer element and cysteine derivatives are used in cancer chemoprevention, we intend to develop a complex of zinc and cysteine-derivatives as potent, non-toxic anticancer agents. Herein, we synthesized and characterized cysteine based ligand, 2-[(2-Hydroxy-3-methoxy-benzylidene)-amino]-3-mercapto-propionic acid and its Zn-complex, which are found to be non-toxic towards normal human PBMC. Data also revealed that only Zn-complex exhibited remarkable apoptosis in drug-sensitive CCRF-CEM and multidrug-resistant CEM/ADR5000 cancer cells as assessed by MTT, Cell cycle and AnnexinV binding assay...
November 6, 2017: Environmental Toxicology and Pharmacology
https://www.readbyqxmd.com/read/29143485/synthesis-molecular-modeling-and-biological-evaluation-of-4-5-aryl-3-thiophen-2-yl-4-5-dihydro-1h-pyrazol-1-yl-benzenesulfonamides-towards-acetylcholinesterase-carbonic-anhydrase-i-and-ii-enzymes
#3
Cem Yamali, Halise Inci Gul, Abdulilah Ece, Parham Taslimi, Ilhami Gulcin
In the present study, 4-[5-aryl-3-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-1-yl] benzenesulfonamides were synthesized and inhibition effects on AChE, hCA I and hCA II were evaluated. Ki values of the compounds towards hCA I were in the range of 24.2±4.6-49.8±12.8 nM while they were in the range of 37.3±9.0-65.3±16.7 nM towards hCA II. Ki values of the Acetazolamide were 282.1±19.7 nM and 103.60±27.6 nM towards both isoenzymes, respectively. The compounds inhibited AChE with Ki in the range of 22.7±10.3-109...
November 16, 2017: Chemical Biology & Drug Design
https://www.readbyqxmd.com/read/29129530/glutamylation-regulates-transport-specializes-function-and-sculpts-the-structure-of-cilia
#4
Robert O'Hagan, Malan Silva, Ken C Q Nguyen, Winnie Zhang, Sebastian Bellotti, Yasmin H Ramadan, David H Hall, Maureen M Barr
Ciliary microtubules (MTs) are extensively decorated with post-translational modifications (PTMs), such as glutamylation of tubulin tails. PTMs and tubulin isotype diversity act as a "tubulin code" that regulates cytoskeletal stability and the activity of MT-associated proteins such as kinesins. We previously showed that, in C. elegans cilia, the deglutamylase CCPP-1 affects ciliary ultrastructure, localization of the TRP channel PKD-2 and the kinesin-3 KLP-6, and velocity of the kinesin-2 OSM-3/KIF17, whereas a cell-specific α-tubulin isotype regulates ciliary ultrastructure, intraflagellar transport, and ciliary functions of extracellular vesicle (EV)-releasing neurons...
November 2, 2017: Current Biology: CB
https://www.readbyqxmd.com/read/29127862/frondoside-a-potentiates-the-effects-of-conventional-therapeutic-agents-in-acute-leukemia
#5
F H Sajwani, P Collin, T E Adrian
Acute leukemia is the major cause of mortality in hematological malignancies. Despite improvement of survival with current chemotherapies, patients die from the disease or side-effects of treatment. Thus, new therapeutic agents are needed. Frondoside A is a triterpenoid glycoside originally isolated from the sea cucumber, Cucumaria frondosa that has potent antitumor effects in various cancers. The current study investigated the effects of frondoside A in acute leukemia cell lines alone and in combination with drugs used for this malignancy...
November 8, 2017: Leukemia Research
https://www.readbyqxmd.com/read/29125822/liposclerosing-myxofibrous-tumor-a-rare-tumor-of-proximal-femur
#6
Ozan Beytemür, Ümit Seza Tetikkurt, Cem Albay, Gonca Kavşut, Akif Güleç
Liposclerosing myxofibrous tumor is a very rarely observed benign fibro-osseous lesion, which contains complex histological structures. It was first described in the year 1986. Histopathological examination of the lesion may show myxoid areas, osteoclastic activity, bone trabeculae similar to fibrous dysplasia, fat necrosis, ischemic ossification and rarely cartilage components. This lesion, which is particularly localized to the proximal femur, is thought to be associated with fibrous dysplasia. In this case report, we aim to present a liposclerosing myxofibrous tumor case, which was treated surgically, in light of the literature review...
December 2017: Eklem Hastalıkları Ve Cerrahisi, Joint Diseases & related Surgery
https://www.readbyqxmd.com/read/29115653/bridge-treatment-for-early-cholecystectomy-in-geriatric-patients-with-acute-cholecystitis-percutaneous-cholecystostomy
#7
Sezgin Zeren, Zülfü Bayhan, Cengiz Koçak, Uğur Kesici, Mehmet Korkmaz, Mehmet Fatih Ekici, Mustafa Cem Algın, Faik Yaylak
BACKGROUND: The main cause of acute cholecystitis (AC) is gallstones, and the incidence of gallstones in elderly patients is high. METHODS: In this study, we aimed to investigate the efficacy of percutaneous cholecystostomy (PC) before early cholecystectomy in geriatric patients with AC. This retrospective study included 85 patients undergoing laparoscopic or conventional cholecystectomy during early stage of calculous AC. RESULTS: All patients were over 65 years old and were divided into two groups: Group I, PC plus early cholecystectomy and Group II, only cholecystectomy without PC...
November 2017: Ulusal Travma Ve Acil Cerrahi Dergisi, Turkish Journal of Trauma & Emergency Surgery: TJTES
https://www.readbyqxmd.com/read/29115648/correlation-between-ischemia-modified-albumin-and-ranson-score-in-acute-pancreatitis
#8
Cem Emir Güldoğan, Murat Özgür Kılıç, İlhan Balamir, Mesut Tez, Turan Turhan
BACKGROUND: Although Ranson score is the most commonly used prognostic model in the severity of acute pancreatitis (AP), ischemia-modified albumin (IMA) has been reported as a novel biomarker of various ischemia-based diseases in recent years. The aim of the present study is to investigate the correlation between Ranson score and IMA in patients with AP. METHODS: Forty-three patients with AP were included in the study. All patients were classified as mild and severe AP...
November 2017: Ulusal Travma Ve Acil Cerrahi Dergisi, Turkish Journal of Trauma & Emergency Surgery: TJTES
https://www.readbyqxmd.com/read/29115647/clinical-infection-in-burn-patients-and-its-consequences
#9
Cem Emir Güldoğan, Murat Kendirci, Deniz Tikici, Emre Gündoğdu, Ahmet Çınar Yastı
BACKGROUND: Burn injuries facilitate invasive infections and sepsis not only by destroying the continuity of the protective skin barrier but also through systemic effects. The burn wound, blood, and urine samples are frequently cultured to determine the pathogen agent. The aim of this study was to analyze pathogen growth in patients' cultures confirmed as "infection positive" by the hospital Infection Control Committee and to assess the clinical implications of these growths. METHODS: Hospitalized patients included in the study were those with a total burned body surface area of >10% and "presence of infection" confirmed by the Infection Control Committee...
November 2017: Ulusal Travma Ve Acil Cerrahi Dergisi, Turkish Journal of Trauma & Emergency Surgery: TJTES
https://www.readbyqxmd.com/read/29114787/maternal-%C3%AE-blocker-use-and-fetal-cardiac-anomalies
#10
Elif Keskin-Arslan, Ali Akoz, Yusuf-Cem Kaplan
No abstract text is available yet for this article.
November 1, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/29111506/increasing-the-impact-factor-in-the-ethical-way
#11
Cem Uzun
No abstract text is available yet for this article.
November 7, 2017: Balkan Medical Journal
https://www.readbyqxmd.com/read/29110240/manipulating-transmit-and-receive-sensitivities-of-radiofrequency-surface-coils-using-shielded-and-unshielded-high-permittivity-materials
#12
Manushka V Vaidya, Cem M Deniz, Christopher M Collins, Daniel K Sodickson, Riccardo Lattanzi
OBJECTIVE: To use high-permittivity materials (HPM) positioned near radiofrequency (RF) surface coils to manipulate transmit/receive field patterns. MATERIALS AND METHODS: A large HPM pad was placed below the RF coil to extend the field of view (FOV). The resulting signal-to-noise ratio (SNR) was compared with that of other coil configurations covering the same FOV in simulations and experiments at 7 T. Transmit/receive efficiency was evaluated when HPM discs with or without a partial shield were positioned at a distance from the coil...
November 6, 2017: Magma
https://www.readbyqxmd.com/read/29104075/corrigendum-to-small-molecule-inhibitor-of-cbf%C3%AE-runx-binding-for-runx-transcription-factor-driven-cancers-ebiomedicine-8-2016-117-131
#13
Anuradha Illendula, Jane Gilmour, Jolanta Grembecka, Venkata Sesha Srimath Tirumala, Adam Boulton, Aravinda Kuntimaddi, Charles Schmidt, Lixin Wang, John A Pulikkan, Hongliang Zong, Mahmut Parlak, Cem Kuscu, Anna Pickin, Yunpeng Zhou, Yan Gao, Lauren Mishra, Mazhar Adli, Lucio H Castilla, Roger A Rajewski, Kevin A Janes, Monica L Guzman, Constanze Bonifer, John H Bushweller
No abstract text is available yet for this article.
October 31, 2017: EBioMedicine
https://www.readbyqxmd.com/read/29102929/three-dimensional-laser-scanning-confocal-analysis-of-conjunctival-microcysts-in-glaucomatous-patients-before-and-after-trabeculectomy
#14
Silvio DI Staso, Luca Agnifili, Angela DI Gregorio, Hilary Climastone, Emilio Galassi, Vincenzo Fasanella, Marco Ciancaglini
BACKGROUND/AIM: In glaucoma, conjunctival epithelial microcysts (CEM) have been extensively investigated by means of laser scanning confocal microscopy. In the present case series, we examined eight glaucomatous patients undergoing trabeculectomy to obtain a 3-dimensional (3-D) characterization of CEM. MATERIALS AND METHODS: Image acquisition was performed in z-scan automatic volume mode by Heidelberg Retina Tomograph III/Rostock Cornea Module and a series of 40 images of 300×300 μm (384×384 pixels) to a maximum depth of 40 μm were acquired throughout the upper bulbar conjunctiva before (at the site planned for surgery) and eight weeks after trabeculectomy...
November 2017: In Vivo
https://www.readbyqxmd.com/read/29102481/intravascular-papillary-endothelial-hyperplasia-of-the-foot
#15
Merdan Serin, Dincer Altinel, Cem Leblebici, Oguzhan Okcu, Sevgi Kurt Yazar
A case of intravascular papillary endothelial hyperplasia is presented. This proliferation usually forms inside thrombotic processes. It is critical to be able distinguish these lesions from low-grade angiosarcomas because they can have similar pathologic findings.
November 1, 2017: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/29101778/financial-aspects-of-bile-duct-injuries
#16
Ozgkıour Palaz Alı, Abdil Cem Ibis, Basak Gurtekin
BACKGROUND Major bile duct injury is the most worrisome complication of cholecystectomy. There is no detailed data about the incidence or treatment-related costs of bile duct injuries in Turkey. We aimed to determine prevalence and therapeutic costs of patients with major biliary duct injuries managed in our department, and further estimate a projection of these parameters at the national level. MATERIAL AND METHODS All patients admitted due to bile duct injury during cholecystectomy from 2011 to 2014 were included...
November 4, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/29101643/dosimetric-comparison-of-3-dimensional-conformal-radiotherapy-volumetric-modulated-arc-therapy-and-helical-tomotherapy-for-postoperative-gastric-cancer-patients
#17
Cem Onal, Yemliha Dölek, Berna Akkuş Yıldırım
PURPOSE: To compare dosimetric data for the planning target volume (PTV) and organs at risk (OARs) between 3-dimensional conformal radiotherapy (3DCRT), volumetric modulated arc therapy (VMAT), and helical tomotherapy [1]. MATERIALS AND METHODS: The dosimetric data for 15 gastric cancer patients treated with 3DCRT, VMAT, or HT techniques were used. Cumulative dosimetric parameters, homogeneity index (HI), and conformal index (CI) were compared for the PTV and OARs...
November 3, 2017: Japanese Journal of Radiology
https://www.readbyqxmd.com/read/29101437/comparison-of-the-efficacy-of-homologous-and-autologous-platelet-rich-plasma-prp-for-treating-androgenic-alopecia
#18
Bilsev Ince, Mehmet Emin Cem Yildirim, Mehmet Dadaci, Mustafa Cihat Avunduk, Nedim Savaci
BACKGROUND: Androgenetic alopecia (AGA), the most common cause of hair loss in both sexes, accounts for 95% of all cases of hair loss. Although the literature has suggested that both nonactivated (n-PRP) and activated autologous (a-PRP) PRP can be used to treat AGA, we did not find any study investigating the use of homologous PRP (h-PRP) for this purpose. Also, to the best of our knowledge, there are no studies comparing the efficacy of h-PRP, a-PRP, or n-PRP on AGA therapy. OBJECTIVES: The aim of this study was to compare the increase in hair density, average number of platelets, complications, preparation, and duration of application in the treatment of AGA using a-PRP, n-PRP, and h-PRP...
November 3, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/29100780/amphiphilic-derivatives-of-3%C3%AE-17%C3%AE-3-hydroxyandrost-5-ene-17-carboxylic-acid
#19
Zülal Özdemir, Uladzimir Bildziukevich, David Šaman, Libor Havlíček, Lucie Rárová, Lucie Navrátilová, Zdeněk Wimmer
A series of amphiphilic derivatives of (3β,17β)-3-hydroxyandrost-5-ene-17-carboxylic acid (1) with the polyamine spermine and three other diamines, 1,2-diaminoethane, piperazine and cadaverine, were synthesized and their antimicrobial activity and cytotoxicity were investigated. Among the target compounds, several ones showed antimicrobial activity on Gram positive and Gram negative microorganisms. The most active compounds were 20 (Streptococcus mutans CCM 7409, 3.125 µM), 16 (Streptococcus mutans CCM 7409, 12...
October 31, 2017: Steroids
https://www.readbyqxmd.com/read/29099045/gene-editing-in-human-lymphoid-cells-role-for-donor-dna-type-of-genomic-nuclease-and-cell-selection-method
#20
Anastasia Zotova, Elena Lopatukhina, Alexander Filatov, Musa Khaitov, Dmitriy Mazurov
Programmable endonucleases introduce DNA breaks at specific sites, which are repaired by non-homologous end joining (NHEJ) or homology recombination (HDR). Genome editing in human lymphoid cells is challenging as these difficult-to-transfect cells may also inefficiently repair DNA by HDR. Here, we estimated efficiencies and dynamics of knockout (KO) and knockin (KI) generation in human T and B cell lines depending on repair template, target loci and types of genomic endonucleases. Using zinc finger nuclease (ZFN), we have engineered Jurkat and CEM cells with the 8...
November 2, 2017: Viruses
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