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https://www.readbyqxmd.com/read/28098730/novel-classification-system-for-combined-hamartoma-of-the-retina-and-retinal-pigment-epithelium
#1
Vaidehi S Dedania, Cem Ozgonul, David N Zacks, Cagri G Besirli
PURPOSE: To develop an anatomical classification scheme for combined hamartoma of the retina and retinal pigment epithelium (RPE) and specify recommendations for follow-up interval. METHODS: Retrospective review of patients with combined hamartoma of the retina and RPE examined during a 7-year period (2008-2015). The clinical presentation, fundus examination, and optical coherence tomography were analyzed. RESULTS: Lesions were classified based on location, fundus features, and optical coherence tomography findings...
January 16, 2017: Retina
https://www.readbyqxmd.com/read/28097489/enhanced-histone-acetylation-in-the-infralimbic-prefrontal-cortex-is-associated-with-fear-extinction
#2
Sarfraj Ahmad Siddiqui, Sanjay Singh, Vandana Ranjan, Rajesh Ugale, Sudipta Saha, Anand Prakash
The molecular processes that establish fear memory are complex and involve a combination of genetic and epigenetic influences. Dysregulation of these processes can manifest in humans as a range of fear-related anxiety disorders like post-traumatic stress disorders (PTSD). In the present study, immunohistochemistry for acetyl H3, H4, c-fos, CBP (CREB-binding protein) in the infralimbic prefrontal cortex (IL-PFC) and prelimbic prefrontal cortex (PL-PFC) of mPFC (medial prefrontal cortex) and basal amygdala (BA), lateral amygdala (LA), centrolateral amygdala (CeL), centromedial amygdala (CeM) of the amygdala was performed to link region-specific histone acetylation to fear and extinction learning...
January 17, 2017: Cellular and Molecular Neurobiology
https://www.readbyqxmd.com/read/28096926/congenital-anterior-urethral-diverticulum-presenting-as-a-scrotal-mass-in-a-two-year-old-child
#3
Ali Gürağaç, Hasan Cem Irkilata, Nahit Yunusov, Zafer Demirer
Here, we describe a case of congenital anterior urethral diverticulum (CAUD) in a two-year-old boy, who presented with right inguinoscrotal swelling that mimicked a spermatic cord cyst or hydrocele. Accurate diagnosis was made intraoperatively by retrograde urethrography. Open diverticulectomy and primary urethroplasty were performed for its management. The clinical presentation, diagnosis, and the management of this rare condition is discussed.
November 2016: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/28090659/the-effect-of-intradetrusor-botulinum-neurotoxin-type-a-on-urinary-ngf-tgf-beta-1-timp-2-levels-in-children-with-neurogenic-detrusor-overactivity-due-to-myelodysplasia
#4
Tuncay Top, Cagri Akin Sekerci, Banu Isbilen-Basok, Yiloren Tanidir, Ilker Tinay, Ferruh Kemal Isman, Cem Akbal, Ferruh Simsek, Tufan Tarcan
AIMS: The aim of this study was to determine the value of urine nerve growth factor (NGF), transforming growth factor beta 1 (TGF-Beta-1), tissue inhibitor of matrix metalloproteinase 2 (TIMP-2) levels to predict the urodynamic profile before and after botulinum neurotoxin type A (BoNT-A) treatment in children with myelodysplasia. METHODS: This prospective study included 15 children with myelodysplasia who underwent intradetrusor BoNT-A injections due to neurogenic detrusor overactivity (NDOA)...
January 16, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/28089978/rituximab-retreatment-in-rheumatoid-arthritis-in-a-real-life-cohort-data-from-the-cererra-collaboration
#5
Katerina Chatzidionysiou, Elisabeth Lie, Galina Lukina, Merete L Hetland, Ellen-Margrethe Hauge, Karel Pavelka, Cem Gabay, Almut Scherer, Dan Nordström, Helena Canhao, Maria José Santos, Matija Tomsic, Ziga Rotar, M Victoria Hernández, Juan Gomez-Reino, Ioan Ancuta, Tore K Kvien, Ronald van Vollenhoven
OBJECTIVE: Several aspects of rituximab (RTX) retreatment in rheumatoid arthritis (RA) need to be further elucidated. The aim of this study was to describe the effect of repeated courses of RTX on disease activity and to compare 2 retreatment strategies, fixed-interval versus on-flare retreatment, in a large international, observational, collaborative study. METHODS: In the first analysis, patients with RA who received at least 4 cycles with RTX were included. In the second analysis, patients who received at least 1 RTX retreatment and for whom information about the strategy for retreatment was available were identified...
January 15, 2017: Journal of Rheumatology
https://www.readbyqxmd.com/read/28079175/interstitial-atoms-enable-joint-twinning-and-transformation-induced-plasticity-in-strong-and-ductile-high-entropy-alloys
#6
Zhiming Li, Cemal Cem Tasan, Hauke Springer, Baptiste Gault, Dierk Raabe
High-entropy alloys (HEAs) consisting of multiple principle elements provide an avenue for realizing exceptional mechanical, physical and chemical properties. We report a novel strategy for designing a new class of HEAs incorporating the additional interstitial element carbon. This results in joint activation of twinning- and transformation-induced plasticity (TWIP and TRIP) by tuning the matrix phase's instability in a metastable TRIP-assisted dual-phase HEA. Besides TWIP and TRIP, such alloys benefit from massive substitutional and interstitial solid solution strengthening as well as from the composite effect associated with its dual-phase structure...
January 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28077417/aid-is-a-key-regulator-of-myeloid-erythroid-differentiation-and-dna-methylation-in-hematopoietic-stem-progenitor-cells
#7
Hiroyoshi Kunimoto, Anna Sophia McKenney, Cem Meydan, Kaitlyn Shank, Abbas Nazir, Franck Rapaport, Benjamin Durham, Francine E Garrett-Bakelman, Elodie Pronier, Alan H Shih, Ari Melnick, Jayanta Chaudhuri, Ross L Levine
Recent studies have reported activation-induced cytidine deaminase (AID) and ten-eleven-translocation (TET) family members regulate active DNA demethylation. Genetic alterations of TET2 occur in myeloid malignancies and hematopoietic specific loss of Tet2 induces aberrant hematopoietic stem cell (HSC) self-renewal/differentiation, implicating TET2 as a master regulator of normal and malignant hematopoiesis. Despite the functional link between AID and TET in epigenetic gene regulation, the role of AID loss in hematopoiesis and myeloid transformation remains to be investigated...
January 11, 2017: Blood
https://www.readbyqxmd.com/read/28077341/irisin-and-oxytocin-as-predictors-of-metabolic-parameters-in-obese-children
#8
Ciğdem Binay, Cem Paketçi, Savaş Güzel, Nedim Samancı
OBJECTIVE: Irisin and oxytocin can affect energy homeostasis and have been proposed to play an important role in reducing obesity and diabetes. We aimed to determine the relationship between metabolic parameters (including irisin and oxytocin levels) and anthropometric parameters in obese children. METHODS: Ninety obese children (mean age, 13.85 ± 1.63 years) and 30 healthy controls (mean age, 14.32 ± 1.58 years) were enrolled in this study. Anthropometric and laboratory parameters (glucose, insulin, lipid, oxytocin, and irisin levels) were analysed...
January 12, 2017: Journal of Clinical Research in Pediatric Endocrinology
https://www.readbyqxmd.com/read/28077254/use-of-the-smartphone-for-end-vertebra-selection-in-scoliosis
#9
Murad Pepe, Onur Kocadal, Abdullah Iyigun, Zafer Gunes, Ertugrul Aksahin, Cem Nuri Aktekin
OBJECTIVES: The aim of our study was to develop a smartphone-aided end vertebra selection method and to investigate its effectiveness in Cobb angle measurement. METHODS: Twenty-nine adolescent idiopathic scoliosis patients' pre-operative posteroanterior scoliosis radiographs were used for end vertebra selection and Cobb angle measurement by standard method and smartphone-aided method. Measurements were performed by 7 examiners. The intraclass correlation coefficient was used to analyze selection and measurement reliability...
January 8, 2017: Acta Orthopaedica et Traumatologica Turcica
https://www.readbyqxmd.com/read/28074453/laparoscopic-resection-and-intracorporeal-anastomosis-of-perforated-small-bowel-caused-by-fish-bone-ingestion
#10
Ahmet Cem Dural, Muhammet Ferhat Çelik, Hakan Yiğitbaş, Cevher Akarsu, Mahmut Doğan, Halil Alış
Presently described is case of a 52-year-old man who was admitted to the emergency department with 3-day history of epigastric pain. Abdominal examination revealed diffuse tenderness and muscle guarding. Plain abdominal X-ray showed free subdiaphragmatic air. The patient underwent diagnostic laparoscopy with presumptive diagnosis of peptic ulcer perforation. Laparoscopy showed several inflamed, edematous jejunal loops with proximal obstruction and perforation by an impacted fish bone. Completely intracorporeal resection and anastomosis using laparoscopic linear stapler was performed and segment of resected bowel was removed through trocar site...
November 2016: Ulusal Travma Ve Acil Cerrahi Dergisi, Turkish Journal of Trauma & Emergency Surgery: TJTES
https://www.readbyqxmd.com/read/28069177/increased-expression-of-integrin-linked-kinase-during-decidualization-regulates-the-morphological-transformation-of-endometrial-stromal-cells
#11
Chih-Feng Yen, Sung Hoon Kim, Shuen-Kuei Liao, Cem Atabekoglu, Serpil Uckac, Aydin Arici, Sefa Arlier, Chyi-Long Lee, Hsin-Shih Wang, Umit A Kayisli
OBJECTIVE: To study the impact of integrin-linked kinase (ILK) in endometrial stromal cells (ESCs) during decidualization. DESIGN: Laboratory study with the use of human endometrium. SETTING: University hospital. PATIENT(S): Fertile reproductive-age women who had not received hormonal treatment for 3 months before tissue collection. INTERVENTION(S): Endometrium tissue collection, in vitro decidualization of isolated ESCs, and small interfering (si) RNA transfection...
January 6, 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28064123/arsenic-treatment-and-power-generation-with-a-dual-chambered-fuel-cell-with-anionic-and-cationic-membranes-using-nahco3-anolyte-and-hcl-or-nacl-catholyte
#12
Hubdar Ali Maitlo, Jung Hwan Kim, Joo Yang Park
Dual-chambered fuel cells with an iron anode and an air-carbon cathode separated by an ion exchange membranes have been used to treat arsenate during power production. To select an effective catholyte, the dual-chambered fuel cell consisted 90 mL of 0.1 M HCl or 0.5 M NaCl as the catholyte and 1 L of 0.1 M NaHCO3 as the anolyte at an initial pH 5. The 0.1 M HCl was an effective catholyte, with which 1 ppm arsenate in 1 L of anolyte was reduced to 5 ppb in 1 h, and the maximum power density was about 6...
December 30, 2016: Chemosphere
https://www.readbyqxmd.com/read/28062897/the-results-of-ultrasonography-guided-percutaneous-radiofrequency-ablation-in-hyperparathyroid-patients-in-whom-surgery-is-not-feasible
#13
Ismail Cem Sormaz, Arzu Poyanlı, Sami Açar, Ahmet Yalın İşcan, İlker Ozgur, Fatih Tunca, Yasemin Giles Senyürek
BACKGROUND: The aim of the study was to evaluate the results of ultrasonography (US)-guided percutaneous radiofrequency ablation (RFA) in hyperparathyroid patients who refused surgery or had high surgical risks. PATIENTS AND METHODS: Five patients with hyperparathyroidism (HPT) underwent US-guided RFA for a single hyperfunctioning parathyroid lesion. Post-ablation serum calcium and parathormone (PTH) assays were performed. All patients underwent imaging studies 6 months after the ablation to visualize the post-ablation change in the size of the treated parathyroid lesions...
January 6, 2017: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/28058165/evaluation-of-follow-up-and-treatment-results-in-coats-disease
#14
Zafer Cebeci, Şerife Bayraktar, Yusuf Cem Yılmaz, Samuray Tuncer, Nur Kır
OBJECTIVES: The aim of this study was to evaluate the clinical features, follow-up and treatment results of patients diagnosed with Coats' disease. MATERIALS AND METHODS: Medical records of 27 patients diagnosed with Coats' disease in our clinic were reviewed retrospectively. All patients underwent complete ophthalmological examination and fundus photography was taken. Disease stage and treatment methods used were recorded. RESULTS: Twenty-seven eyes of 27 patients were included in the study...
October 2016: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/28056530/association-of-lymphocyte-to-monocyte-ratio-with-the-mortality-in-patients-with-st-elevation-myocardial-infarction-who-underwent-primary-percutaneous-coronary-intervention
#15
Tuncay Kiris, Aykan Çelik, Eser Variş, Erol Akan, Zehra Ilke Akyildiz, Mustafa Karaca, Cem Nazli, Abdullah Dogan
We investigated whether the lymphocyte-to-monocyte ratio (LMR) 48 hours after admission is related to 30-day and long-term mortality in patients with ST-elevation myocardial infarction (STEMI) who were treated with primary percutaneous coronary intervention (PCI). We evaluated 318 consecutive patients with STEMI who were undergoing primary PCI. The relationship between the LMR48h and all-cause mortality (30-day and long-term) was analyzed by categorizing the patients into tertiles (T) according to LMR48h-T1 (>2...
January 1, 2017: Angiology
https://www.readbyqxmd.com/read/28051878/teicoplanin-use-during-breastfeeding
#16
Yusuf Cem Kaplan, Elif Keskin-Arslan, Selin Acar, Hilal Erol-Coskun
No abstract text is available yet for this article.
January 4, 2017: Breastfeeding Medicine: the Official Journal of the Academy of Breastfeeding Medicine
https://www.readbyqxmd.com/read/28044309/improving-histopathology-laboratory-productivity-process-consultancy-and-a3-problem-solving
#17
Kutsal Yörükoğlu, Erdener Özer, Birsen Alptekin, Cem Öcal
OBJECTIVE: The ISO 17020 quality program has been run in our pathology laboratory for four years to establish an action plan for correction and prevention of identified errors. In this study, we aimed to evaluate the errors that we could not identify through ISO 17020 and/or solve by means of process consulting. Process consulting is carefully intervening in a group or team to help it to accomplish its goals. MATERIAL AND METHOD: The A3 problem solving process was run under the leadership of a 'workflow, IT and consultancy manager'...
2017: Türk Patoloji Dergisi
https://www.readbyqxmd.com/read/28044304/review-of-hydatid-cyst-with-focus-on-cases-with-unusual-locations
#18
Sevinç Hallaç Keser, Ayşegül Selek, Dilek Ece, Cem Cahit Barişik, Sibel Şensu, Gonca Gül Geçmen, Selma Şengiz Erhan, Şermin Çoban Kökten, Nagehan Özdemir Barişik, Aylin Ege Gül
OBJECTIVE: This study has been conducted so as to contribute to health statistics of hydatid cyst by the data obtained from our clinic, and to discuss hydatid cysts in unusual locations. MATERIAL AND METHOD: Cases diagnosed as hydatid cyst at Dr. Lutfi Kirdar Kartal Research and Education Hospital Pathology Clinic between 2007 and 2015 have been evaluated based on criteria such as age, sex and location. RESULTS: A total of 364 cases, 209 females and 155 males, have been included in the study...
2017: Türk Patoloji Dergisi
https://www.readbyqxmd.com/read/28044299/mucosal-malignant-melanoma-of-nasal-cavity-recurring-a-year-after-radiotherapy
#19
Cem Çomunoğlu, Gamze Mocan Kuzey, Mete Inançli, Füsun Baba, Hanife Özkayalar
OBJECTIVE: Sinonasal mucosal malignant melanoma is a rare entity. In this report we present a nasal mucosal malignant melanoma case with its histopathological and clinical features. CASE REPORT: An 88-year-old female patient presented with epistaxis a month ago. Examination revealed a polypoid mass lesion of right nasal cavity originating from the middle concha. Her medical history revealed that she had been found to have a mass lesion in the right nasal cavity 15 months ago...
2017: Türk Patoloji Dergisi
https://www.readbyqxmd.com/read/28040126/prediction-of-gestational-diabetes-mellitus-at-first-trimester-in-low-risk-pregnancies
#20
Pınar Kumru, Resul Arisoy, Emre Erdogdu, Oya Demirci, Mustecep Kavrut, Cem Ardıc, Nihan Aslaner, Aysen Ozkoral, Aktug Ertekin
OBJECTIVE: We aimed to assess the relationship among the sex hormone-binding globulin (SHBG), homeostasis model assessment (HOMA), glycosylated hemoglobin (HbA1c), and cholesterol panel values to predict subsequent gestational diabetes mellitus (GDM) in low-risk pregnancies. MATERIALS AND METHODS: Thirty-eight pregnant women with GDM and 295 low-risk pregnant women without GDM were included in this study. Maternal blood samples were obtained during the first trimester examination to determine the SHBG, HbA1c, fasting blood glucose, insulin, thyroid stimulating hormone (TSH), free thyroxine, total cholesterol, triglycerides (TG), high-density lipoprotein cholesterol, and low-density lipoprotein cholesterol (LDL-C) levels...
December 2016: Taiwanese Journal of Obstetrics & Gynecology
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