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https://www.readbyqxmd.com/read/29242820/establishing-a-live-cartilage-on-cartilage-interface-for-tribological-testing
#1
Robert L Trevino, Jonathan Stoia, Michel P Laurent, Carol A Pacione, Susan Chubinskaya, Markus A Wimmer
Mechano-biochemical wear encompasses the tribological interplay between biological and mechanical mechanisms responsible for cartilage wear and degradation. The aim of this study was to develop and start validating a novel tribological testing system, which better resembles the natural joint environment through incorporating a live cartilage-on-cartilage articulating interface, joint specific kinematics, and the application of controlled mechanical stimuli for the measurement of biological responses in order to study the mechano-biochemical wear of cartilage...
March 2017: Biotribology
https://www.readbyqxmd.com/read/29240838/recognized-focused-practice-does-sub-specialty-designation-offer-value-to-the-neurosurgeon
#2
Maya A Babu, Linda M Liau, Fredric B Meyer
Vehicles for life-long assessment such as Maintenance of Certification tend to focus on generalist neurosurgical knowledge. However, as neurosurgeons advance in their careers, they tend to narrow their practice and increase volumes in certain specific types of operations. Failing to test the type of procedures most relevant to the practitioner is a lost opportunity to improve the knowledge and practice of the individual neurosurgeon. In this study, we assess the neurosurgical community's appetite for designations of board-recognized Recognized Focused Practice (RFP)...
2017: PloS One
https://www.readbyqxmd.com/read/29240744/an-osteoarthritis-model-of-care-should-be-a-national-priority-for-new-zealand
#3
Jennifer Baldwin, Andrew Briggs, Warwick Bagg, Peter Larmer
Osteoarthritis is highly prevalent, disabling and costly to the person and the community. The burden of this chronic condition is predicted to increase dramatically over the coming decades. Healthcare spending on osteoarthritis is unsustainable and action is needed to improve care delivery. At present, there is an over-emphasis on surgical and pharmacological interventions, despite evidence supporting conservative treatments such as exercise, weight loss and education. While clinical guidelines provide recommendations regarding best practice (ie, what to do), they fail to address how to operationalise these recommendations into clinical practice...
December 15, 2017: New Zealand Medical Journal
https://www.readbyqxmd.com/read/29213229/reflex-modification-audiometry-reveals-dual-roles-for-olivocochlear-neurotransmission
#4
Paul D Allen, Anne E Luebke
Approximately 15% of American adults report some degree of difficulty hearing in a noisy environment or have auditory filtering difficulties. There are objective clinical tests of auditory filtering, yet few tests exist for mouse models that do not rely on extensive training. We have used reflex modification audiometry (RMA) and developed exclusion criteria for the mouse model. This RMA based test makes use of the acoustic startle response (ASR) and the ability of prepulses to inhibit the ASR [i.e., prepulse inhibition (PPI)] to assess the mouse's ability to detect prepulse signals presented in quiet or embedded in masking noise...
2017: Frontiers in Cellular Neuroscience
https://www.readbyqxmd.com/read/29192619/tinnitus-medial-olivocochlear-system-and-music-exposure-in-adolescents
#5
María Hinalaf, Ana L Maggi, Mercedes X Hüg, Pablo Kogan, Jorge Pérez Villalobo, Ester C Biassoni
INTRODUCTION: The most common cause of tinnitus is the exposure to noise; in the case of adolescents, music is the main sound source they are exposed to. Currently, one of the hypotheses about the genesis of tinnitus is related to the deterioration in the functioning of the medial olivocochlear system (MOCS). AIM: The aim of this study was to determine the presence or absence of tinnitus in adolescents with normal hearing and to relate it to: (a) the functioning of the MOCS, by the contralateral suppression of the transient evoked otoacoustic emissions (TEOAEs) and (b) the musical general exposure (MGE)...
March 2017: Noise & Health
https://www.readbyqxmd.com/read/29158039/association-between-the-american-board-of-internal-medicine-s-general-internist-s-maintenance-of-certification-requirement-and-mammography-screening-for-medicare-beneficiaries
#6
Bradley M Gray, Jonathan L Vandergrift, Rebecca S Lipner
BACKGROUND: Breast cancer is a leading cause of death in the United States. Continuing medical education programs such as the American Board of Internal Medicine's Maintenance of Certification (MOC) program can increase early detection of cancers by educating physicians about the benefits of screening. Did the imposition of American Board of Internal Medicine's MOC requirement affect guideline-compliant mammography screening? METHOD: To address this question, we took advantage of a natural experiment that occurred when one group of general internists was required to complete MOC by 2001 because they initially certified in 1991 (MOC required) and another group was grandfathered out of this requirement because they initially certified in 1989 (MOC grandfathers)...
November 17, 2017: Women's Health Issues: Official Publication of the Jacobs Institute of Women's Health
https://www.readbyqxmd.com/read/29153596/the-aging-neurosurgeon-when-is-enough-enough-attitudes-toward-ceasing-practice-and-testing-in-late-career
#7
Maya A Babu, Linda M Liau, Robert J Spinner, Fredric B Meyer
OBJECTIVE: To present the first wide-scale survey to assess perceptions of testing the aging neurosurgeon. PATIENTS AND METHODS: This study included 4899 neurosurgeons, 2435 American Board of Neurological Surgery Diplomates participating in Maintenance of Certification (MOC), 1440 Diplomates certified before 1999 (grandfathered), and 1024 retired Diplomates. We developed an online confidential survey conducted from March 1, 2016, to May 31, 2016. We received 1449 responses overall (30% response rate)...
November 14, 2017: Mayo Clinic Proceedings
https://www.readbyqxmd.com/read/29135685/olivocochlear-efferent-activity-is-associated-with-the-slope-of-the-psychometric-function-of-speech-recognition-in-noise
#8
Ian B Mertes, Erin C Wilbanks, Marjorie R Leek
OBJECTIVES: The medial olivocochlear (MOC) efferent system can modify cochlear function to improve sound detection in noise, but its role in speech perception in noise is unclear. The purpose of this study was to determine the association between MOC efferent activity and performance on two speech-in-noise tasks at two signal-to-noise ratios (SNRs). It was hypothesized that efferent activity would be more strongly correlated with performance at the more challenging SNR, relative to performance at the less challenging SNR...
November 9, 2017: Ear and Hearing
https://www.readbyqxmd.com/read/29134475/synchronized-spontaneous-otoacoustic-emissions-provide-a-signal-to-noise-ratio-advantage-in-medial-olivocochlear-reflex-assays
#9
James D Lewis
Detection of medial olivocochlear-induced (MOC) changes to transient-evoked otoacoustic emissions (TEOAE) requires high signal-to-noise ratios (SNR). TEOAEs associated with synchronized spontaneous (SS) OAEs exhibit higher SNRs than TEOAEs in the absence of SSOAEs, potentially making the former well suited for MOC assays. Although SSOAEs may complicate interpretation of MOC-induced changes to TEOAE latency, recent work suggests SSOAEs are not a problem in non-latency-dependent MOC assays. The current work examined the potential benefit of SSOAEs in TEOAE-based assays of the MOC efferents...
November 13, 2017: Journal of the Association for Research in Otolaryngology: JARO
https://www.readbyqxmd.com/read/29122423/efferent-modulation-of-pre-neural-and-neural-distortion-products
#10
S B Smith, K Ichiba, D S Velenovsky, B Cone
Distortion product otoacoustic emissions (DPOAEs) and distortion product frequency following responses (DPFFRs) are respectively pre-neural and neural measurements associated with cochlear nonlinearity. Because cochlear nonlinearity is putatively linked to outer hair cell electromotility, DPOAEs and DPFFRs may provide complementary measurements of the human medial olivocochlear (MOC) reflex, which directly modulates outer hair cell function. In this study, we first quantified MOC reflex-induced DPOAE inhibition at spectral fine structure peaks in 22 young human adults with normal hearing...
October 26, 2017: Hearing Research
https://www.readbyqxmd.com/read/29119671/a-microribbon-hybrid-structure-of-coox-moc-encapsulated-in-n-doped-carbon-nanowire-derived-from-mof-as-efficient-oxygen-evolution-electrocatalysts
#11
Tan Huang, Yu Chen, Jong-Min Lee
Developing highly efficient electrocatalysts for oxygen evolution is vital for renewable and sustainable energy production and storage. Herein, nitrogen-doped carbon encapsulated CoOx-MoC heterostructures are reported for the first time as high performance oxygen evolution electrocatalysts. The composition can be tuned by the addition of a Mo source to form a nanowire-assembled hierarchically porous microstructure, which can enlarge the specific surface area, thus exposing more active sites, facilitating mass transport and charge transfer...
November 9, 2017: Small
https://www.readbyqxmd.com/read/29113220/pax8-is-a-potential-marker-for-the-diagnosis-of-primary-epithelial-ovarian-cancer
#12
Hong-Juan Chai, Qing Ren, Qin Fan, Liu Ye, Guang-Ye Du, Hua-Wen Du, Wei Xu, Yue Li, Lan Zhang, Zhong-Ping Cheng
The present study aimed to investigate the clinical significance of paired-box 8 (PAX8) in primary epithelial ovarian cancer (PEOC). Using immunohistochemical (IHC) staining, the expression of PAX8 in 60 patients with PEOC, 20 patients with ovarian benign lesions and 10 patients with metastatic ovarian cancer (MOC), was examined based on the clinicopathological profiles of the patients. The correlation between PAX8 expression and the clinicopathological parameters or prognosis of patients was statistically analyzed...
November 2017: Oncology Letters
https://www.readbyqxmd.com/read/29061621/detection-and-management-of-familial-hypercholesterolaemia-in-primary-care-in-australia-protocol-for-a-pragmatic-cluster-intervention-study-with-pre-post-intervention-comparisons
#13
Diane E Arnold-Reed, Tom Brett, Lakkhina Troeung, Alistair Vickery, Jacquie Garton-Smith, Damon Bell, Jing Pang, Tegan Grace, Caroline Bulsara, Ian Li, Max Bulsara, Gerald F Watts
INTRODUCTION: Familial hypercholesterolaemia (FH), an autosomal dominant disorder of lipid metabolism, results in accelerated onset of atherosclerosis if left untreated. Lifelong treatment with diet, lifestyle modifications and statins enable a normal lifespan for most patients. Early diagnosis is critical. This protocol trials a primary care-based model of care (MoC) to improve detection and management of FH. METHODS AND ANALYSIS: Pragmatic cluster intervention study with pre-post intervention comparisons in Australian general practices...
October 22, 2017: BMJ Open
https://www.readbyqxmd.com/read/29046431/a-survey-of-perceived-effectiveness-of-part-4-maintenance-of-certification
#14
Joel S Tieder, Sean P Prall, Jimmy Beck, Erin Alberda, Debra Jensen, Deepthi Nair, Jan D Carline
OBJECTIVES: Evaluative assessment is needed to inform improvement of Part 4 Maintenance of Certification (MOC), a large-scale program that aims to improve physician knowledge, engagement, and skills in quality improvement (QI). We sought to determine if Part 4 MOC participation improves perceived educational and clinical outcomes by piloting a new physician survey. METHODS: We administered a new online survey (MOC Practice, Engagement, Attitude, and Knowledge Survey) to physicians at the beginning and end of a Part 4 MOC project sponsored by a pediatric hospital's American Board of Medical Specialties' portfolio program during 2015...
November 2017: Hospital Pediatrics
https://www.readbyqxmd.com/read/29040158/the-association-of-changing-practice-settings-on-maintenance-of-certification-exam-outcomes-a-comparative-study-of-general-internists-over-time
#15
Andrew T Jones, Brendan J Barnhart, Steven J Durning, Rebecca S Lipner
PURPOSE: To investigate how changing to or from solo practice settings relates to maintenance of certification (MOC) exam performance. METHOD: The authors conducted a retrospective analysis of exam pass/fail outcomes for 7,112 physicians who successfully completed their initial MOC cycle from 2000 to 2004. Initial physician MOC practice characteristics records, demographic information, and exam performance were linked with exam pass/fail outcomes from their second MOC cycle from 2006 to 2014 (5,215 physicians after attrition)...
October 16, 2017: Academic Medicine: Journal of the Association of American Medical Colleges
https://www.readbyqxmd.com/read/29028636/effects-and-unforeseen-consequences-of-accessing-references-on-a-maintenance-of-certification-examination-findings-from-a-national-study
#16
Richard A Feinberg, Daniel Jurich, Lauren M Foster
PURPOSE: Increasing criticism of maintenance of certification (MOC) examinations has prompted certifying boards to explore alternative assessment formats. The purpose of this study was to examine the effect of allowing test takers to access reference material while completing their MOC Part III standardized examination. METHOD: Item response data were obtained from 546 physicians who completed a medical subspecialty MOC examination between 2013 and 2016. To investigate if accessing references was related to better performance, an analysis of covariance was conducted on the MOC examination scores with references (access or no access) as the between-groups factor and scores from the physicians' initial certification examination as a covariate...
October 12, 2017: Academic Medicine: Journal of the Association of American Medical Colleges
https://www.readbyqxmd.com/read/29024755/performance-of-pediatric-rehabilitation-medicine-candidates-on-the-subspecialty-board-certification-examination-from-2003-to-2015
#17
Sherilyn W Driscoll, Teresa L Massagli, Mary A McMahon, Mikaela M Raddatz, David W Pruitt, Kevin P Murphy
BACKGROUND: Pediatric rehabilitation medicine (PRM) physicians enter the field via several pathways. It is unknown whether different training pathways impact performance on the American Board of Physical Medicine and Rehabilitation (ABPMR) PRM Examination and Maintenance of Certification (MOC) Examination. OBJECTIVES: To describe the examination performance of candidates on the ABPMR PRM Examination according to their type of training (physiatrists with a clinical PRM focus, accredited or unaccredited fellowship training, separate pediatric and physical medicine and rehabilitation residencies, or combined pediatrics/physical medicine and rehabilitation residencies) and to compare candidates' performance on the PRM Examination with their initial ABPMR certification and MOC Examinations...
October 10, 2017: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/29024544/squamous-cell-carcinoma-in-serous-effusions-avoiding-pitfalls-in-this-rare-encounter
#18
Christopher LePhong, Elizabeth W Hubbard, Stuart Van Meter, Laurentia Nodit
BACKGROUND: With advent of personalized medicine, precise classification of malignant tumors becomes essential. Squamous cell carcinoma (SCC) is rarely found in serous effusions and has morphologic and immunohistochemical (IHC) overlap with other neoplasms. METHODS: 17-year review identified 49 fluids from 26 patients where SCC was recognized. RESULTS: SCC was more frequent in pleural fluid (84%) and rare in other effusions. Lung SCC was common (65%), followed by head and neck (16%), with other origins less represented...
October 11, 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/28994846/3d-self-assembly-of-ultrafine-molybdenum-carbide-confined-in-n-doped-carbon-nanosheets-for-efficient-hydrogen-production
#19
Haiqing Wang, Xiaobin Xu, Bing Ni, Haoyi Li, Wei Bian, Xun Wang
Electrochemical water splitting has been intensively pursued as a promising approach to produce clean and sustainable hydrogen fuel. However, the lack of low-cost and high-performance electrocatalysts for the hydrogen evolution reaction (HER) hinders the large-scale application. Herein, we have rationally designed and synthesized 3D self-assembly architectures assembled from ultrafine MoC nanoparticles (0D) uniformly embedded within N-doped carbon nanosheets (2D) for the HER via a simple protocol. The well-organized 3D nanostructures are composed of very small MoC nanocrystallites (<2 nm) and free-stretching conductive carbon nanosheets with high specific surface areas and abundant mesopores, which can expose more active sites and facilitate electron/ion transport pathways...
October 26, 2017: Nanoscale
https://www.readbyqxmd.com/read/28984895/new-balance-new-beginning
#20
Joey Berlin
Following the passage of TMA-supported legislation to loosen maintenance of certification (MOC) requirements, Texas is now a national leader in reducing the onerousness of MOC on physicians. What will the new law do once it takes effect at the beginning of 2018, and what could it do to keep more physicians in practice?
October 1, 2017: Texas Medicine
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