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https://www.readbyqxmd.com/read/28538522/frequency-specificity-and-left-ear-advantage-of-medial-olivocochlear-efferent-modulation-a-study-based-on-stimulus-frequency-otoacoustic-emission
#1
Dongjia Xing, Qin Gong
The medial olivocochlear (MOC) bundle is an auditory nucleus that projects efferent nerve fibers to the outer hair cells (OHCs) for synaptic innervation. The aim of the present study was to investigate the possible existence of frequency and ear specificity in MOC efferent modulation, as well as how MOC activation influences cochlear tuning. Stimulus frequency otoacoustic emissions (SFOAEs) were used to study MOC efferent modulation. Therefore, the current experiment was designed to compare the degree of SFOAE suppression in the both ears of 20 individuals at 1, 2, 4, and 8 kHz...
May 19, 2017: Neuroreport
https://www.readbyqxmd.com/read/28516994/3d-ordered-porous-moxc-x-1-or-2-for-advanced-hydrogen-evolution-and-li-storage
#2
Hong Yu, Haosen Fan, Jiong Wang, Yun Zheng, Zhengfei Dai, Yizhong Lu, Junhua Kong, Xin Wang, Young Jin Kim, Qingyu Yan, Jong-Min Lee
3D ordered porous structures of MoxC are prepared with different Mo to C ratios and tested for two possible promising applications: hydrogen evolution reaction (HER) through water splitting and lithium ion batteries (LIBs). Mo2C and MoC with 3D periodic ordered structures are prepared with a similar process but different precursors. The 3D ordered porous MoC exhibits excellent cycling stability and rate performance as an anode material for LIBs. A discharge capacity of 450.9 mA h g(-1) is maintained up to 3000 cycles at 10...
May 18, 2017: Nanoscale
https://www.readbyqxmd.com/read/28495749/holliday-junction-resolvases-mediate-chloroplast-nucleoid-segregation
#3
Yusuke Kobayashi, Osami Misumi, Masaki Odahara, Kota Ishibashi, Masafumi Hirono, Kumi Hidaka, Masayuki Endo, Hiroshi Sugiyama, Hiroshi Iwasaki, Tsuneyoshi Kuroiwa, Toshiharu Shikanai, Yoshiki Nishimura
Holliday junctions, four-stranded DNA structures formed during homologous recombination, are disentangled by resolvases that have been found in prokaryotes and eukaryotes but not in plant organelles. Here, we identify monokaryotic chloroplast 1 (MOC1) as a Holliday junction resolvase in chloroplasts by analyzing a green alga Chlamydomonas reinhardtii mutant defective in chloroplast nucleoid (DNA-protein complex) segregation. MOC1 is structurally similar to a bacterial Holliday junction resolvase, resistance to ultraviolet (Ruv) C, and genetically conserved among green plants...
May 12, 2017: Science
https://www.readbyqxmd.com/read/28486820/maintenance-of-certification-what-s-to-know
#4
Pat Rich
The Maintenance of Certification (MOC) Program administered by the Royal College of Physicians and Surgeons applies to all Fellows of the Royal College including dermatologists. It is mandatory for those who wish to maintain their fellowship in the Royal College and can be critical for maintaining licensure requirements. Residents can take advantage of the program before becoming Fellows of the Royal College. Fellows and MOC Program participants in the Royal College MOC Program must complete a minimum of 400 credits during a 5-year cycle and a minimum of 40 credits in each year of the cycle...
May 1, 2017: Journal of Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/28481475/phase-and-facet-control-of-molybdenum-carbide-nanosheet-observed-by-in-situ-tem
#5
Ziyuan Lin, Lejuan Cai, Wei Lu, Yang Chai
Transition metal carbides are of great potential for electrochemical applications. The phase and facet of molybdenum carbides greatly affect the electrochemical performance. Carburization of MoO3 inside a transmission electron microscope to monitor the growth process of molybdenum carbides is performed. Carbon sources with different activities are used and the controllable growth of molybdenum carbides is investigated. The results show that the relatively inert amorphous carbon film produces Mo2 C, where the interstitial sites formed by hexagonal closed packing molybdenum atoms are partially occupied by carbon atoms...
May 8, 2017: Small
https://www.readbyqxmd.com/read/28420960/contralateral-inhibition-of-click-and-chirp-evoked-human-compound-action-potentials
#6
Spencer B Smith, Jeffery T Lichtenhan, Barbara K Cone
Cochlear outer hair cells (OHC) receive direct efferent feedback from the caudal auditory brainstem via the medial olivocochlear (MOC) bundle. This circuit provides the neural substrate for the MOC reflex, which inhibits cochlear amplifier gain and is believed to play a role in listening in noise and protection from acoustic overexposure. The human MOC reflex has been studied extensively using otoacoustic emissions (OAE) paradigms; however, these measurements are insensitive to subsequent "downstream" efferent effects on the neural ensembles that mediate hearing...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28420510/gene-set-based-analysis-of-mucinous-ovarian-carcinoma
#7
Chia-Ming Chang, Peng-Hui Wang, Huann-Cheng Horng
OBJECTIVE: Mucinous ovarian carcinoma (MOC) is an uncommon subtype of epithelial ovarian cancers, and the pathogenesis is still poorly understood because of its rarity. We conducted a gene set-based analysis to investigate the pathogenesis of MOC by integrating microarray gene expression datasets based on the regularity of functions defined by gene ontology or canonical pathway databases. MATERIALS AND METHODS: Forty-five pairs of MOC and normal ovarian tissue sample gene expression profiles were downloaded from the National Center for Biotechnology Information Gene Expression Omnibus database...
April 2017: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28419451/do-state-continuing-medical-education-requirements-for-physicians-improve-clinical-knowledge
#8
Jonathan L Vandergrift, Bradley M Gray, Weifeng Weng
OBJECTIVE: To evaluate the effect of state continuing medical education (CME) requirements on physician clinical knowledge. DATA SOURCES: Secondary data for 19,563 general internists who took the Internal Medicine Maintenance of Certification (MOC) examination between 2006 and 2013. STUDY DESIGN: We took advantage of a natural experiment resulting from variations in CME requirements across states over time and applied a difference-in-differences methodology to measure associations between changes in CME requirements and physician clinical knowledge...
April 16, 2017: Health Services Research
https://www.readbyqxmd.com/read/28406257/nitrogen-doped-carbon-encapsulating-%C3%AE-moc-ni-heterostructures-for-efficient-oxygen-evolution-electrocatalysts
#9
Xueping Zhang, Liang Huang, Yujie Han, Miao Xu, Shaojun Dong
Developing efficient and earth-abundant oxygen evolution reaction (OER) electrocatalysts is of great importance in renewable energy research. Herein, we report nitrogen-doped carbon encapsulating γ-MoC/Ni heterostructures (γ-MoC/Ni@NC) for the first time as efficient OER electrocatalysts. The composites can be controlled by the addition of a Mo source to form a nanoparticle-assembled hierarchically porous nanostructure, which can enlarge the specific surface area, thus exposing more active sites. Moreover, we demonstrate that the formation of γ-MoC@Ni heterostructures and the resulting synergistic effect between γ-MoC and Ni can facilitate the reaction kinetics, leading to significantly improved OER activity with an onset overpotential of merely 240 mV, and a low overpotential of 310 mV to afford a current density of 10 mA cm(-2)...
May 4, 2017: Nanoscale
https://www.readbyqxmd.com/read/28399027/relatively-poor-survival-of-mucinous-ovarian-carcinoma-in-advanced-stage-a-systematic-review-and-meta-analysis
#10
Michiel Simons, Leon Massuger, Jolien Bruls, Johan Bulten, Steven Teerenstra, Iris Nagtegaal
OBJECTIVE: Overall, patients with mucinous ovarian carcinoma (MOC) are considered to have a better prognosis compared with the whole group of nonmucinous carcinomas. However, some studies indicate that patients with advanced-stage MOC might have a worse prognosis than those with advanced-stage serous ovarian carcinoma (SOC). We carried out a systematic review and meta-analysis of the current literature. MATERIALS AND METHODS: A comprehensive literature search was carried out identifying 19 articles that compare survival of patients with MOC and patients with SOC...
May 2017: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/28396709/human-ipsc-derived-myocardium-on-chip-with-capillary-like-flow-for-personalized-medicine
#11
Bradley W Ellis, Aylin Acun, U Isik Can, Pinar Zorlutuna
The heart wall tissue, or the myocardium, is one of the main targets in cardiovascular disease prevention and treatment. Animal models have not been sufficient in mimicking the human myocardium as evident by the very low clinical translation rates of cardiovascular drugs. Additionally, current in vitro models of the human myocardium possess several shortcomings such as lack of physiologically relevant co-culture of myocardial cells, lack of a 3D biomimetic environment, and the use of non-human cells. In this study, we address these shortcomings through the design and manufacture of a myocardium-on-chip (MOC) using 3D cell-laden hydrogel constructs and human induced pluripotent stem cell (hiPSC) derived myocardial cells...
March 2017: Biomicrofluidics
https://www.readbyqxmd.com/read/28390599/medial-olivocochlear-function-in-children-with-poor-speech-in-noise-performance-and-language-disorder
#12
Caroline Nunes Rocha-Muniz, Renata Mota Mamede Carvallo, Eliane Schochat
OBJECTIVES: Contralateral masking of transient-evoked otoacoustic emissions is a phenomenon that suggests an inhibitory effect of the olivocochlear efferent auditory pathway. Many studies have been inconclusive in demonstrating a clear connection between this system and a behavioral speech-in-noise listening skill. The purpose of this study was to investigate the activation of a medial olivocochlear (MOC) efferent in children with poor speech-in-noise (PSIN) performance and children with language impairment and PSIN (SLI + PSIN)...
May 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28390134/primordial-odontogenic-tumor-an-immunohistochemical-profile
#13
R Bologna-Molina, T Mikami, V Pereira-Prado, F-R Pires, R Carlos-Bregni, A Mosqueda-Taylor
BACKGROUND: Primordial Odontogenic Tumor (POT) is a recently described odontogenic tumor characterized by a variably cellular loose fibrous tissue with areas similar to the dental papilla, covered by cuboidal to columnar epithelium that resembles the internal epithelium of the enamel organ, surrounded at least partly by a delicate fibrous capsule. The purpose of this study was to investigate the possible histogenesis and biological behavior of this rare tumor by means of a wide immunohistochemical analysis of its epithelial and mesenchymal components...
May 1, 2017: Medicina Oral, Patología Oral y Cirugía Bucal
https://www.readbyqxmd.com/read/28377198/pediatrician-maintenance-of-certification-using-american-board-of-pediatrics-performance-improvement-modules
#14
Marina Arvanitis, Neal A deJong, Laurel K Leslie, Darren A DeWalt, Gregory D Randolph, Kori B Flower
BACKGROUND: From 2010-2014, pediatricians completed Part 4 Maintenance of Certification (MOC) through practice- or organization-developed quality improvement (QI) activities approved by the American Board of Pediatrics (ABP). Organization-developed activities were online modules, such as the ABP's Performance Improvement Modules (PIMs), through which pediatricians implemented QI strategies in practice, and reported quality measures. OBJECTIVES: Aim 1) Assess the proportion of pediatricians who completed practice- vs organization-developed QI activities for Part 4 MOC, and test the relationship between activities and pediatrician demographics...
April 1, 2017: Academic Pediatrics
https://www.readbyqxmd.com/read/28370486/clinical-presentation-and-outcomes-of-patients-with-type-1-monoclonal-cryoglobulinemia
#15
Surbhi Sidana, S Vincent Rajkumar, Angela Dispenzieri, Martha Q Lacy, Morie A Gertz, Francis K Buadi, Suzanne R Hayman, David Dingli, Prashant Kapoor, Wilson I Gonsalves, Ronald S Go, Yi Lisa Hwa, Nelson Leung, Amie L Fonder, Miriam A Hobbs, Steven R Zeldenrust, Stephen J Russell, John A Lust, Robert A Kyle, Shaji K Kumar
We describe a series of 102 patients diagnosed from January 1, 1990 to December 31, 2015 with Type 1 monoclonal cryoglobulinemia (MoC). Symptoms were seen in 89 (87%) patients, including: cutaneous symptoms in 64 (63%) patients, with purpura (n=43, 42%) and ulcers/gangrene (n=35, 34%) being most common; neurological findings in 33 (32%) patients, most frequently sensory neuropathy (n=24, 24%); vasomotor symptoms, mainly Raynaud's phenomenon in 25 (25%); arthralgias in 24 (24%); and renal manifestations, primarily glomerulonephritis in 14 (14%) patients...
March 29, 2017: American Journal of Hematology
https://www.readbyqxmd.com/read/28329760/low-temperature-hydrogen-production-from-water-and-methanol-using-pt-%C3%AE-moc-catalysts
#16
Lili Lin, Wu Zhou, Rui Gao, Siyu Yao, Xiao Zhang, Wenqian Xu, Shijian Zheng, Zheng Jiang, Qiaolin Yu, Yong-Wang Li, Chuan Shi, Xiao-Dong Wen, Ding Ma
Polymer electrolyte membrane fuel cells (PEMFCs) running on hydrogen are attractive alternative power supplies for a range of applications, with in situ release of the required hydrogen from a stable liquid offering one way of ensuring its safe storage and transportation before use. The use of methanol is particularly interesting in this regard, because it is inexpensive and can reform itself with water to release hydrogen with a high gravimetric density of 18.8 per cent by weight. But traditional reforming of methanol steam operates at relatively high temperatures (200-350 degrees Celsius), so the focus for vehicle and portable PEMFC applications has been on aqueous-phase reforming of methanol (APRM)...
April 6, 2017: Nature
https://www.readbyqxmd.com/read/28321449/catalysts-of-self-assembled-pt-ceo2-%C3%AE-rich-core-shell-nanoparticles-on-3d-ordered-macroporous-ce1-xzrxo2-for-soot-oxidation-nanostructure-dependent-catalytic-activity
#17
Yuechang Wei, Jinqing Jiao, Xindong Zhang, Baofang Jin, Zhen Zhao, Jing Xiong, Yazhao Li, Jian Liu, Jianmei Li
The catalytic performance in heterogeneous catalytic reactions consisting of solid reactants is strongly dependent on the nanostructure of the catalysts. Metal-oxides core-shell (MOCS) nanostructures have potential to enhance the catalytic activity for soot oxidation reactions as a result of optimizing the density of active sites located at the metal-oxide interface. Here, we report a facile strategy for fabricating nanocatalysts with self-assembled Pt@CeO2-δ-rich core-shell nanoparticles (NPs) supported on three-dimensionally ordered macroporous (3DOM) Ce1-xZrxO2via the in situ colloidal crystal template (CCT) method...
March 21, 2017: Nanoscale
https://www.readbyqxmd.com/read/28320044/multiple-concomitant-oral-cavity-cancers-incidence-management-and-outcomes
#18
Huang-Kai Kao, Mohamed Abdelrahman, Yenlin Huang, Chia-Hsuan Tsai, Megias J Barrera, Ngan-Ming Tsang, Adam J Couves, Ming-Huei Cheng, Kai-Ping Chang
BACKGROUND: Little is known about the appropriate treatment and long-term survival of patients with multiple concomitant oral cavity cancers (MOC). The aim of this study was to clarify the clinicopathological features of MOC, to compare the prognosis of MOC patients with that of patients with single oral cavity cancers (SOC), and to describe reconstructive options based on the concept of economy in autologous tissue transfer. METHODS: Data from 603 patients diagnosed with at least one squamous cell carcinoma of the oral cavity who underwent surgery for primary oral cavity cancers between 2006 and 2014 were reviewed retrospectively to identify MOC patients...
March 20, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28318248/ultrastable-1d-europium-complex-for-simultaneous-and-quantitative-sensing-of-cr-iii-and-cr-vi-ions-in-aqueous-solution-with-high-selectivity-and-sensitivity
#19
Jingjuan Liu, Guanfeng Ji, Jiannan Xiao, Zhiliang Liu
A unique metal-organic complex (MOC) with formula [Eu2(tpbpc)4·CO3·4H2O]·DMF·solvent (Htpbpc = 4'-[4,2';6',4″]-terpyridin-4'-yl-biphenyl-4-carboxylic acid) has been successfully constructed under solvothermal conditions. The Eu complex, as proved by structural analysis, exhibits a fascinating 1D linear-type chain structure which is further extended to a 3D H-bonded supramolecular framework. The luminescent investigations confirm that the emission behavior of the Eu complex possesses excellent water stability and pH stability, and it is the first example of a MOC-based fluorescent probe with high selectivity, high sensitivity, and low detection limit, targeting Cr(III) and Cr(VI) (CrO4(2-)/Cr2O7(2-)) ions in aqueous solution...
March 20, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28315410/is-lymphadenectomy-necessary-in-mucinous-ovarian-cancer-a-single-institution-experience
#20
Ivan Salgado-Ceballos, Jazmín Ríos, Delia Pérez-Montiel, Lenny Gallardo, Salim Barquet-Muñoz, Rosa Salcedo-Hernández, Carlos Pérez-Plasencia, Luis Alonso Herrera, David Francisco Cantú de León
BACKGROUND: According to the International Federation of Gynecology and Obstetrics (FIGO) guidelines, every patient diagnosed with ovarian cancer (OC) should undergo a complete staging procedure to adequately assess tumor spread. The role of lymphadenectomy in the initial management of primary early mucinous ovarian cancer (MOC) remains unclear. OBJECTIVE: To describe the prevalence of pelvic and para-aortic node metastases in MOC. MATERIALS AND METHODS: The records of patients with MOC treated at our Institute during January 2005 to December 2011 were assessed...
March 14, 2017: International Journal of Surgery
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