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https://www.readbyqxmd.com/read/28345187/novel-biomarkers-for-prostate-cancer-an-evidence-based-review-for-use-in-clinical-practice
#1
REVIEW
Vikram M Narayan, Badrinath R Konety, Christopher Warlick
Prostate cancer is a heterogeneous disease with disparate outcomes. Traditional clinical parameters are limited in their ability to differentiate between these cases, and there is uncertainty regarding management strategies. A number of novel biomarkers have emerged, but how best to use them at the point of care remains confusing. In the present review, we describe the most common novel biomarkers, their key supporting literature, and propose a meaningful algorithm for their use in clinical practice. To identify commercially available prostate cancer diagnostic tests, we carried out a PubMed literature search (through May 2016)...
March 27, 2017: International Journal of Urology: Official Journal of the Japanese Urological Association
https://www.readbyqxmd.com/read/28342028/disparities-in-knee-and-hip-arthroplasty-outcomes-an-observational-analysis-of-the-acs-nsqip-clinical-registry
#2
Peter Cram, Gillian Hawker, John Matelski, Bheeshma Ravi, Andrew Pugely, Rajiv Gandhi, Timothy Jackson
BACKGROUND: Disparities in total joint arthroplasty (TJA) have largely been studied in single center studies and using administrative data. Our objective was to investigate differences in TJA outcomes in white men, black men, white women, and black women using a large international registry. METHODS: We used 2010-2013 data from the ACS-NSQIP to identify four groups of adults (white men, black men, white women, black women) who underwent primary total knee arthroplasty (TKA) or total hip arthroplasty (THA)...
March 24, 2017: Journal of Racial and Ethnic Health Disparities
https://www.readbyqxmd.com/read/28340592/the-impact-of-the-share-35-policy-on-racial-and-ethnic-disparities-in-access-to-liver-transplantation-for-patients-with-end-stage-liver-disease-in-the-united-states-an-analysis-from-unos-database
#3
Yefei Zhang
BACKGROUND: The Share 35 policy was instituted in June 2013 by the United Network for Organ Sharing (UNOS) in order to reduce death on liver transplant waiting list. The effect of this policy on racial and ethnic disparities in access to liver transplantation has not been examined. METHODS: A total of 14,585 adult patients registered for liver transplantation between 2012 and 2015 were identified from UNOS database. Logistic and proportional hazards models were used to model the effects of race and ethnicity on access to liver transplantation...
March 24, 2017: International Journal for Equity in Health
https://www.readbyqxmd.com/read/28340082/disparities-in-health-care-quality-among-asian-children-with-special-health-care-needs
#4
Esther Son, Susan L Parish, Leah Igdalsky
There is a dearth of information on the quality of health care for Asian American children and particularly Asian children with special health care needs (CSHCN). The goal of this article was to determine whether there were disparities in quality of health care for Asian CSHCN, whose experiences have not been studied. Data were derived from the 2009-2010 National Survey of Children with Special Health Care Needs (ns = 355 non-Hispanic Asian children and 4,343 non-Hispanic white CSHCN). Bivariate and multivariate logistic regression analyses were conducted to examine the relationship between racial identity (that is, non-Hispanic white and non-Hispanic Asian) and quality of health care...
March 2, 2017: Health & Social Work
https://www.readbyqxmd.com/read/28339616/time-trends-in-smoking-onset-by-sex-and-race-ethnicity-among-adolescents-and-young-adults-findings-from-the-2006-2013-national-survey-on-drug-use-and-health
#5
Azure B Thompson, Paul D Mowery, Jacob Kraemer Tebes, Sherry A McKee
Introduction: During the 2000s the number of adolescents who became new smokers in the United States declined while the number of young adults who did so increased. However, we do not know among which demographic groups these changes occurred. Methods: We analyzed data from the 2006 to 2013 National Survey of Drug Use and Health (n = 180 079). Multivariate linear regression models were used to assess annual trends in smoking onset and log-binomial regression models to assess changes over time in the risk of smoking onset among young adults (18- to 25-years-old) relative adolescents (12- to 17-years-old)...
January 30, 2017: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/28337847/efficacy-of-environmental-and-acceptance-based-enhancements-to-behavioral-weight-loss-treatment-the-enact-trial
#6
Meghan L Butryn, Evan M Forman, Michael R Lowe, Amy A Gorin, Fengqing Zhang, Katherine Schaumberg
OBJECTIVE: This study was designed to compare weight loss through a traditional behavioral treatment (BT) approach that integrated skills for managing the obesogenic food environment (BT + E) with an approach that integrated environmental and acceptance-based skills (BT + EA). Moderators were examined as an exploratory aim. METHODS: Adults (N = 283) were randomly assigned to treatment condition and provided with 26 group-based sessions over the course of 12 months...
March 23, 2017: Obesity
https://www.readbyqxmd.com/read/28336354/educational-disparities-in-mortality-between-adults-aged-50-64-and-66-79-years-u-s
#7
Jiemin Ma, Sean Altekruse, Candace Cosgrove, Farhad Islami, Ahmedin Jemal
INTRODUCTION: This study estimated differences in educational disparities in mortality between ages 50-64 and 66-79 years in the U.S. and explored factors contributing to the differences. METHODS: Based on the follow-up of a nationally representative cohort in the National Longitudinal Mortality Study 2002-2011, relative differences in educational disparities (relative index of inequality) between people aged 50-64 and 66-79 years were calculated for deaths from all causes, cancer, cardiovascular disease, injuries, and other causes by sex and race/ethnicity...
March 20, 2017: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28330732/racial-ethnic-differences-in-weight-loss-strategies-among-us-adults-national-health-and-nutrition-examination-survey-2007-2012
#8
Becky Marquez, Rosenda Murillo
BACKGROUND: Dieting, exercising, and seeking professional help have been associated with intentional weight loss among adults. OBJECTIVE: This study examined the use of diet (eg, ate less, ate less fat, or switched to low-calorie foods), exercise, diet and exercise, and professional help (eg, weight-loss program or prescribed diet pills) for weight loss among non-Hispanic whites, Mexican Americans, and non-Hispanic blacks. DESIGN: Cross-sectional data from the 2007-2012 National Health and Nutrition Examination Survey were used...
March 15, 2017: Journal of the Academy of Nutrition and Dietetics
https://www.readbyqxmd.com/read/28329831/racial-ethnic-disparities-in-influenza-and-pneumococcal-vaccinations-among-nursing-home-residents-a-systematic-review
#9
Jasmine L Travers, Krista L Schroeder, Thomas E Blaylock, Patricia W Stone
This systematic review analyzes research examining racial/ethnic disparities in influenza and pneumococcal vaccination coverage between White and racial/ethnic minority (Black and Hispanic) nursing home residents. A review of the literature for years 1966-2014 using Medline, Web of Science, and PubMed was conducted. The Epidemiological Appraisal Instrument was used to appraise the quality of the 13 included studies. Overall, articles were strong in reporting and data analysis, but weak in sample selection and measurement quality...
January 21, 2017: Gerontologist
https://www.readbyqxmd.com/read/28329641/differences-in-incidence-and-persistence-of-atopic-dermatitis-by-race-ethnicity
#10
M Blomberg, S L Rifas-Shiman, Ca Jr Camargo, D R Gold, J P Thyssen, A A Litonjua, M W Gillman, M M Asgari, E Oken
BackgroundMost studies on racial disparities in childhood atopic dermatitis (AD) did not consider persistent AD or account for differences in vitamin D status.MethodsAmong 1418 children recruited from a Massachusetts HMO into the pre-birth Project Viva cohort, we examined associations of child's race/ethnicity with maternal report of child's AD diagnosis by annual questionnaires. We used multivariable logistic regression adjusted for socio- demographics (maternal education, household income, smoking exposure, parental atopy, breastfeeding duration, child sex) and cord blood 25-hydroxyvitamin D, to estimate odds ratios (OR) of incident AD by early childhood (median age 3...
September 15, 2016: Dermatology Online Journal
https://www.readbyqxmd.com/read/28329429/racial-disparity-in-life-expectancies-and-life-years-lost-associated-with-multiple-obesity-related-chronic-conditions
#11
Su-Hsin Chang, Yao-Chi Yu, Nils P Carlsson, Xiaoyan Liu, Graham A Colditz
OBJECTIVE: This study investigated racial disparity in life expectancies (LEs) and life years lost (LYL) associated with multiple obesity-related chronic conditions (OCCs). METHODS: Data from the Medical Expenditure Panel Survey, 2008-2012, were used. Four OCCs were studied: diabetes, hypertension, coronary heart disease (CHD), and stroke. LE for each subpopulation was simulated by Markov modelling. LYL associated with a disease for a subpopulation was computed by taking the difference between LEs for members of that subpopulation without disease and LEs for members of that subpopulation who had that disease...
March 22, 2017: Obesity
https://www.readbyqxmd.com/read/28325737/measures-matter-the-local-exposure-isolation-lex-is-metrics-and-relationships-between-local-level-segregation-and-breast-cancer-survival
#12
EDITORIAL
Amin Bemanian, Kirsten M M Beyer
Background: The Black-to-White disparity in breast cancer survival is increasing, and racial residential segregation is a potential driver for this trend. However, study findings have been mixed, and no study has comprehensively compared the effectiveness of different local-level segregation metrics in explaining cancer survival.Methods: We proposed a set of new local segregation metrics named local exposure and isolation (LEx/Is) and compared our new local isolation metric with two related metrics, the location quotient (LQ) and the index of concentration at extremes (ICE), across the 102 largest U...
March 21, 2017: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/28325118/is-asthma-associated-with-cognitive-impairments-a-meta-analytic-review
#13
Farzin Irani, Jordan Mark Barbone, Janet Beausoleil, Lynn Gerald
INTRODUCTION: Asthma is a chronic disease with significant health burden and socioeconomic and racial/ethnic disparities related to diagnosis and treatment. Asthma primarily affects the lungs, but can impact brain function through direct and indirect mechanisms. Some studies have suggested that asthma negatively impacts cognition, while others have failed to identify asthma-related cognitive compromise. We aimed to conduct a meta-analysis of cognition in individuals with asthma compared to that in healthy controls...
March 21, 2017: Journal of Clinical and Experimental Neuropsychology
https://www.readbyqxmd.com/read/28323476/state-level-progress-in-reducing-the-black-white-infant-mortality-gap-united-states-1999-2013
#14
Joedrecka S Brown Speights, Samantha Sittig Goldfarb, Brittny A Wells, Leslie Beitsch, Robert S Levine, George Rust
OBJECTIVES: To assess state-level progress on eliminating racial disparities in infant mortality. METHODS: Using linked infant birth-death files from 1999 to 2013, we calculated state-level 3-year rolling average infant mortality rates (IMRs) and Black-White IMR ratios. We also calculated percentage improvement and a projected year for achieving equality if current trend lines are sustained. RESULTS: We found substantial state-level variation in Black IMRs (range = 6...
March 21, 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/28322769/racial-and-ethnic-disparities-in-contraceptive-knowledge-among-women-veterans-in-the-ecuun-study
#15
Elian Rosenfeld, Lisa S Callegari, Florentina E Sileanu, Xinhua Zhao, E Bimla Schwarz, Maria K Mor, Sonya Borrero
OBJECTIVE: To assess whether racial/ethnic disparities in contraceptive knowledge observed in the general US population are also seen among women Veterans served by the Veterans Affairs (VA) healthcare system. STUDY DESIGN: We analyzed data from a national telephone survey of 2302 women Veterans aged 18-44 who had received care within VA in the prior 12months. Twenty survey items assessed women's knowledge about various contraceptive methods. Multivariable logistic regression was used to examine racial/ethnic variation in contraceptive knowledge items, adjusting for age, marital status, education, income, parity, and branch of military service...
March 17, 2017: Contraception
https://www.readbyqxmd.com/read/28322661/cell-phone-information-seeking-explains-blood-pressure-in-african-american-women
#16
Lenette M Jones, Tiffany C Veinot, Susan J Pressler
Although cell phone use and Internet access via cell phone is not marked by racial disparities, little is known about how cell phone use relates to blood pressure and health information seeking behaviors. The purposes of this study were to (a) describe Internet activities, cell phone use, and information seeking; (b) determine differences in blood pressure and information seeking between cell phone information seekers and nonseekers; and (c) examine cell phone information seeking as a predictor of blood pressure in African American women...
January 1, 2017: Western Journal of Nursing Research
https://www.readbyqxmd.com/read/28314574/apol1-a-case-in-point-for-replacing-race-with-genetics
#17
Girish N Nadkarni, Christina M Wyatt, Barbara Murphy, Michael J Ross
Ethnicity-specific differences in apolipoprotein L1 (APOL1) polymorphisms are associated with racial disparities in kidney transplantation outcomes. APOL1 genotyping may better help define graft outcome risk pre-transplantation; however, more research is needed.
April 2017: Kidney International
https://www.readbyqxmd.com/read/28314047/the-role-of-risk-perception-in-flu-vaccine-behavior-among-african-american-and-white-adults-in-the-united-states
#18
Vicki S Freimuth, Amelia Jamison, Gregory Hancock, Donald Musa, Karen Hilyard, Sandra Crouse Quinn
Seasonal flu vaccination rates are low for U.S. adults, with significant disparities between African and white Americans. Risk perception is a significant predictor of vaccine behavior but the research on this construct has been flawed. This study addressed critical research questions to understand the differences between African and white Americans in the role of risk perception in flu vaccine behavior: (1) What is the dimensionality of risk perception and does it differ between the two races?  (2) Were risk perceptions of white and African-American populations different and how were sociodemographic characteristics related to risk for each group? (3) What is the relation between risk perception and flu vaccine behaviors for African Americans and whites? The sample, drawn from GfK's Knowledge Panel, consisted of 838 whites and 819 African Americans...
March 17, 2017: Risk Analysis: An Official Publication of the Society for Risk Analysis
https://www.readbyqxmd.com/read/28302531/resistin-potentiates-chemoresistance-and-stemness-of-breast-cancer-cells-implications-for-racially-disparate-therapeutic-outcomes
#19
Sachin K Deshmukh, Sanjeev K Srivastava, Haseeb Zubair, Arun Bhardwaj, Nikhil Tyagi, Ahmed Al-Ghadhban, Ajay P Singh, Donna L Dyess, James E Carter, Seema Singh
Breast cancer (BC) continues to be the most frequently diagnosed cancer in American women, which disproportionately affects women of African-American (AA) descent. Previously, we reported greater serum levels of resistin in AA BC patients relative to Caucasian-American (CA) patients, and established its role in growth and aggressiveness of breast tumor cells. Here we have investigated the role of resistin in BC-chemoresistance. MDA-MB-231 and MDA-MB-468 BC cells of CA and AA origin, respectively, were incubated with resistin prior to doxorubicin treatment...
March 14, 2017: Cancer Letters
https://www.readbyqxmd.com/read/28302274/pipeline-program-recruits-and-retains-women-and-underrepresented-minorities-in-procedure-based-specialties-a-brief-report
#20
Bonnie S Mason, William Ross, Monique C Chambers, Richard Grant, Michael Parks
As the US population continues to grow in racial and ethnic diversity, we also continue to see healthcare disparities across racial lines. Considerable attention has been given to creating a physician workforce that better reflects the population served by healthcare professionals. To address the low numbers of women and underrepresented minorities in procedural based specialties, Nth Dimensions has sought to address and eliminate healthcare disparities through strategic pipeline initiatives. This is a retrospective observational cohort study of 118 medical students from 29 accredited US medical schools, who were awarded a position in the Nth Dimensions Summer Internship program between 2005 and 2012...
November 17, 2016: American Journal of Surgery
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