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https://www.readbyqxmd.com/read/27922983/current-construct-options-for-revision-of-large-acetabular-defects-a-systematic-review
#1
Marieke Baauw, Miranda L van Hooff, Maarten Spruit
BACKGROUND: Many treatment options are available for the revision of large acetabular defects. Debate continues as to which technique is most effective. METHODS: A systematic review was performed according to the Meta-analysis of Observational Studies in Epidemiology (MOOSE) guidelines to evaluate the effectiveness of interventions for large acetabular defects. Quality assessment was performed next with use of 8 items of the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) checklist for reports of observational studies...
November 8, 2016: JBJS Reviews
https://www.readbyqxmd.com/read/27922981/second-opinion-expert-pathology-in-endometrial-cancer-potential-clinical-implications
#2
Friederike Grevenkamp, Felix Kommoss, Friedrich Kommoss, Sigurd Lax, Falko Fend, Diethelm Wallwiener, Birgitt Schönfisch, Bernhard Krämer, Sara Y Brucker, Florin-Andrei Taran, Annette Staebler, Stefan Kommoss
OBJECTIVE: In cancer patients, the pathology report serves as an important basis for treatment. Therefore, a correct cancer diagnosis is crucial, and diagnostic discrepancies may be of clinical relevance. It was the aim of this study to perform a specialized histopathology review and to investigate potential clinical implications of expert second opinion pathology in endometrial cancer. METHODS: Patients treated for endometrial carcinoma at the Tübingen University Women's hospital between 2003 and 2013 were identified...
December 3, 2016: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/27922796/prevention-and-monitoring-of-cardiac-dysfunction-in-survivors-of-adult-cancers-american-society-of-clinical-oncology-clinical-practice-guideline-summary
#3
Saro H Armenian, Christina Lacchetti, Daniel Lenihan
No abstract text is available yet for this article.
December 6, 2016: Journal of Oncology Practice
https://www.readbyqxmd.com/read/27922569/mode-of-information-delivery-does-not-effect-anesthesia-trainee-performance-during-simulated-perioperative-pediatric-critical-events-a-trial-of-paper-versus-electronic-cognitive-aids
#4
Scott C Watkins, Shilo Anders, Anna Clebone, Elisabeth Hughes, Vikram Patel, Laura Zeigler, Yaping Shi, Matthew S Shotwell, Matthew D McEvoy, Matthew B Weinger
INTRODUCTION: Cognitive aids (CAs), including emergency manuals and checklists, have been recommended as a means to address the failure of healthcare providers to adhere to evidence-based standards of treatment during crisis situations. Unfortunately, users of CAs still commit errors, omit critical steps, fail to achieve perfect adherence to guidelines, and frequently choose to not use CA during both simulated and real crisis events. We sought to evaluate whether the mode in which a CA presents information (ie, paper vs...
December 2016: Simulation in Healthcare: Journal of the Society for Simulation in Healthcare
https://www.readbyqxmd.com/read/27922565/a-perspective-on-brain-gut-communication-the-american-gastroenterology-association-and-american-psychosomatic-society-joint-symposium-on-brain-gut-interactions-and-the-intestinal-microenvironment
#5
Olga C Aroniadis, Douglas A Drossman, Magnus Simren
BACKGROUND: Alterations in brain-gut communication and the intestinal microenvironment have been implicated in a variety of medical and neuropsychiatric diseases. Three central areas require basic and clinical research: (1) how the intestinal microenvironment interacts with the host immune system, central nervous system and enteric nervous system; (2) the role of the intestinal microenvironment in the pathogenesis of medical and neuropsychiatric disease; (3) the effects of diet, prebiotics, probiotics and fecal microbiota transplantation on the intestinal microenvironment and the treatment of disease...
December 2, 2016: Psychosomatic Medicine
https://www.readbyqxmd.com/read/27922502/the-limb-girdle-muscular-dystrophies-and-the-dystrophinopathies
#6
Stanley Jones P Iyadurai, John T Kissel
PURPOSE OF REVIEW: The classic approach to identifying and accurately diagnosing limb-girdle muscular dystrophies (LGMDs) relied heavily on phenotypic characterization and ancillary studies including muscle biopsy. Because of rapid advances in genetic sequencing methodologies, several additional LGMDs have been molecularly characterized, and the diagnostic approach to these disorders has been simplified. This article summarizes the epidemiology, clinical features, and genetic defects underlying the LGMDs...
December 2016: Continuum: Lifelong Learning in Neurology
https://www.readbyqxmd.com/read/27922500/facioscapulohumeral-muscular-dystrophy
#7
Jeffrey M Statland, Rabi Tawil
PURPOSE OF REVIEW: This article describes the clinical characteristics, diagnosis, molecular pathogenesis, and treatment of facioscapulohumeral muscular dystrophy (FSHD). RECENT FINDINGS: FSHD comprises two genetically distinct types that converge on a common downstream pathway of the expression of the toxic protein DUX4. Approximately 95% of patients have FSHD type 1 (FSHD1), in which loss of DNA repetitive elements (D4Z4 repeats) in the subtelomeric region of chromosome 4q causes decreased methylation and epigenetic derepression of DUX4, a gene contained within each D4Z4 repeat...
December 2016: Continuum: Lifelong Learning in Neurology
https://www.readbyqxmd.com/read/27922497/autoimmune-myopathies
#8
Andrew L Mammen
PURPOSE OF REVIEW: This article provides guidelines for diagnosing and treating the different subtypes of autoimmune myopathies. RECENT FINDINGS: The most common subtypes of autoimmune myopathies are dermatomyositis, immune-mediated necrotizing myopathy, antisynthetase syndrome, and overlap syndromes; isolated polymyositis is an exceptionally rare disease. Specific autoantibodies are associated with unique clinical phenotypes and may be used for diagnostic and prognostic purposes, such as to assess the risk of coexisting malignancy...
December 2016: Continuum: Lifelong Learning in Neurology
https://www.readbyqxmd.com/read/27922469/sports-and-driving-with-an-implantable-cardioverter-defibrillator
#9
Aileen M Ferrick, Kevin J Ferrick
Many patients with implantable cardioverter-defibrillators (ICD) want to participate in sports and many need or wish to operate a personal motor vehicle. Healthcare providers need to advise patients regarding restrictions related to these activities in the context of the clinical indication for the ICD. Ethical considerations need to be considered when advising ICD patients of restrictions to reduce risk of injury to themselves and to others when participating in either sports or driving. Shared decision-making is necessary to have ICD patients understand and comply with recommended restrictions...
January 2017: Cardiology in Review
https://www.readbyqxmd.com/read/27922466/smartphone-based-electrocardiographic-and-cardiac-implantable-electronic-device-monitoring
#10
Suneet Mittal
The field of arrhythmia monitoring is changing rapidly. The rapid advent of technology in combination with marked improvements in cellular communication and an increased desire by patients to be actively engaged in their care has ushered in a new era of clinical care. Today, physicians need to think about their patients outside the traditional in-office setting. Two technologies that embody this changing landscape are smartphone-based electrocardiographic (ECG) monitors and remote monitoring of cardiac implantable electronic devices (CIEDs)...
January 2017: Cardiology in Review
https://www.readbyqxmd.com/read/27922230/consensus-statement-on-diagnosis-treatment-and-follow-up-of-cow-s-milk-protein-allergy-among-infants-and-children-in-turkey
#11
Aydan Kansu, Aysel Yüce, Buket Dalgıç, Bülent Enis Şekerel, Fügen Çullu-Çokuğraş, Haluk Çokuğraş
The present paper aims to provide experts' consensus on diagnosis and management of cow's milk protein allergy (CMPA) among infants and children in Turkey, based on review of available evidence-based guidelines, publications and experts' clinical experience. The experts agreed that CMPA diagnosis should be based on symptomatic evaluation and diagnostic elimination diet as followed by implementation of an open challenge test after disappearance of symptoms and confirmation of CMPA diagnosis in re-appearance of symptoms...
2016: Turkish Journal of Pediatrics
https://www.readbyqxmd.com/read/27922168/update-of-the-swiss-guidelines-on-post-treatment-lyme-disease-syndrome
#12
Johannes Nemeth, Enos Bernasconi, Ulrich Heininger, Mohamed Abbas, David Nadal, Carol Strahm, Stefan Erb, Stefan Zimmerli, Hansjakob Furrer, Julie Delaloye, Thierry Kuntzer, Ekkehard Altpeter, Mathias Sturzenegger, Rainer Weber, For The Swiss Society For Infectious Diseases And The Swiss Society For Neurology
Lyme borreliosis is caused by Borrelia burgdorferi sensu lato infection, which responds well to antibiotic therapy in the overwhelming majority of cases. However, despite adequate antibiotic treatment some patients report persisting symptoms which are commonly summarised as post-treatment Lyme disease syndrome (PTLDS). In 2005, the Swiss Society of Infectious Diseases published a case definition for PTLDS. We aimed to review the scientific literature with a special emphasis on the last 10 years, questioning whether the definitions from 2005 are still valid in the light of current knowledge...
2016: Swiss Medical Weekly
https://www.readbyqxmd.com/read/27922153/-radioiodine-therapy-for-benign-thyroid-diseases-version-5-german-guideline
#13
Markus Dietlein, Frank Grünwald, Matthias Schmidt, Peter Schneider, Frederik A Verburg, Markus Luster
The version 5 of the guideline for radioiodine therapy of benign thyroid disorders is an update of the version 4, which was published by the German Society of Nuclear Medicine (Deutsche Gesellschaft für Nuklearmedizin, DGN) in co-ordination with the German Society of Endocrinology (Deutsche Gesellschaft für Endokrinologie, DGE, Sektion Schilddrüse) and the German Society of General- and Visceral-Surgery (Deutsche Gesellschaft für Allgemein- und Viszeralchirurgie, DGAV) in 2007. This guideline was harmonized with the recommendations of the European Association of Nuclear Medicine (EANM)...
December 6, 2016: Nuklearmedizin. Nuclear Medicine
https://www.readbyqxmd.com/read/27921442/nebulized-antibiotics-in-mechanically-ventilated-patients-roadmap-and-challenges
#14
G Poulakou, G Siakallis, S Tsiodras, A Arfaras Melainis, G Dimopoulos
Nebulized antibiotics use has become common practice in the therapeutics of pneumonia in cystic fibrosis patients. There is an increasing interest in their use for respiratory infections in mechanically ventilated (MV) patients in order to a) overcome pharmacokinetic issues in the lung compartment with traditional systemic antibiotic use and b) prevent the emergence of multi-drug-resistant (MDR) pathogens. Areas covered: The beneficial effects of antibiotic nebulization in MV patients e.g. increasing efficacy, reduced toxicity and prevention of resistance are described...
December 6, 2016: Expert Review of Anti-infective Therapy
https://www.readbyqxmd.com/read/27921188/erratum-to-an-international-position-paper-on-mother-infant-perinatal-mental-health-with-guidelines-for-clinical-practice
#15
Ian Brockington, Ruth Butterworth, Nine Glangeaud-Freudenthal
No abstract text is available yet for this article.
December 6, 2016: Archives of Women's Mental Health
https://www.readbyqxmd.com/read/27921167/the-real-world-in-the-clinic-before-and-after-the-establishment-of-guidelines-for-coronary-artery-spasm-a-questionnaire-for-members-of-the-japanese-cine-angio-association
#16
Shozo Sueda, Hiroaki Kohno, Hideaki Yoshino
We investigated the clinical situations and the present knowledge of Japanese cardiologists about coronary artery spasm before and after the establishment of guidelines for this condition in the real world. A questionnaire was developed regarding the number of cases of coronary angiography, percutaneous coronary intervention, and invasive/non-invasive spasm provocation tests before (2008) and after (2014) the establishment of the Japanese Circulation Society (JCS) guidelines for coronary artery spasm and the status of spasm provocation tests...
December 5, 2016: Heart and Vessels
https://www.readbyqxmd.com/read/27921160/european-society-of-urogenital-radiology-esur-guidelines-mr-imaging-of-pelvic-endometriosis
#17
M Bazot, N Bharwani, C Huchon, K Kinkel, T M Cunha, A Guerra, L Manganaro, L Buñesch, A Kido, K Togashi, I Thomassin-Naggara, A G Rockall
: Endometriosis is a common gynaecological condition of unknown aetiology that primarily affects women of reproductive age. The accepted first-line imaging modality is pelvic ultrasound. However, magnetic resonance imaging (MRI) is increasingly performed as an additional investigation in complex cases and for surgical planning. There is currently no international consensus regarding patient preparation, MRI protocols or reporting criteria. Our aim was to develop clinical guidelines for MRI evaluation of pelvic endometriosis based on literature evidence and consensus expert opinion...
December 5, 2016: European Radiology
https://www.readbyqxmd.com/read/27921000/distress-in-infertile-males-in-manipal-india-a-clinic-based-study
#18
Ansha Patel, Podila Satya Venkata Narasimha Sharma, Pratapkumar Narayan, Binu Valsalakumari Sreekumaran Nair, Dinesh Narayanakurup, Praveena Joglekar Pai
BACKGROUND: Being infertile comes as an overwhelming realization for couples trying to conceive. In consideration of rising rates of infertility worldwide, clinicians in India have also begun exploring this field for new possibilities, development and research. The purpose of this study was to estimate the proportion and predictors of infertility specific stress in males diagnosed with primary infertility. METHODS: This cross-sectional research was conducted in an assisted reproduction center, Manipal, India, on 300 infertile married males...
October 2016: Journal of Reproduction & Infertility
https://www.readbyqxmd.com/read/27920810/hyaluronic-acid-in-the-management-of-osteoarthritis-injection-therapies-innovations
#19
Valter Santilli, Marco Paoloni, Massimiliano Mangone, Federica Alviti, Andrea Bernetti
Osteoarthritis (OA) is a chronic degenerative joint disease characterized by pain and progressive functional limitation. Viscosupplementation with intra-articular (IA) hyaluronic acid (HA) could be a treatment option in OA, however recommendations made in different international guidelines for the non-surgical management of OA are not always concordant with regard to the role of IA injection therapies. Results from a recent Italian Consensus Conference underline how IA-HA to treat OA represents a widely used therapy in Italy...
May 2016: Clinical Cases in Mineral and Bone Metabolism
https://www.readbyqxmd.com/read/27920623/factors-influencing-decision-making-for-or-against-adjuvant-and-neoadjuvant-chemotherapy-in-postmenopausal-hormone-receptor-positive-breast-cancer-patients-in-the-evaluate-tm-study
#20
Paul Gaß, Peter A Fasching, Tanja Fehm, Johann de Waal, Mahdi Rezai, Bernd Baier, Gerold Baake, Hans-Christian Kolberg, Martin Guggenberger, Mathias Warm, Nadia Harbeck, Rachel Wuerstlein, Jörg-Uwe Deuker, Peter Dall, Barbara Richter, Grischa Wachsmann, Cosima Brucker, Jan W Siebers, Nikos Fersis, Thomas Kuhn, Christopher Wolf, Hans-Walter Vollert, Georg-Peter Breitbach, Wolfgang Janni, Robert Landthaler, Andreas Kohls, Daniela Rezek, Thomas Noesselt, Gunnar Fischer, Stephan Henschen, Thomas Praetz, Volker Heyl, Thorsten Kühn, Thomas Krauss, Christoph Thomssen, Andre Hohn, Hans Tesch, Christoph Mundhenke, Alexander Hein, Claudia Rauh, Christian M Bayer, Adib Jacob, Katja Schmidt, Erik Belleville, Peyman Hadji, Sara Y Brucker, Matthias W Beckmann, Diethelm Wallwiener, Sherko Kümmel, Christian R Löhberg
BACKGROUND: Decision-making for or against neoadjuvant or adjuvant chemotherapy in postmenopausal patients with hormone receptor-positive breast cancer does not follow any clear guidelines, and some patients may unnecessarily undergo chemotherapy and be exposed to the associated toxicity. The aim of this study was to identify the patient population for whom this issue may bear relevance. METHODS: Patients being treated with letrozole in the prospective multicenter noninterventional EvAluate-TM study were recruited...
October 2016: Breast Care
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