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Akemi Koshiba, Taisuke Mori, Fumitake Ito, Yukiko Tanaka, Osamu Takaoka, Akiko Takahata, Jo Kitawaki
AIM: To assess and compare the uterine volume and endometrium length between women with and without endometriosis, using pelvic magnetic resonance imaging scans. METHODS: In this case-control study, a total of 75 nulligravid women (aged 20-45 years) with regular menstrual cycles whose uterus were free of any surgically confirmed lesions were enrolled. The endometriosis group underwent surgery for endometrioma (n = 39), and the control group underwent surgery for non-endometrioma ovarian cysts (n = 36)...
October 20, 2016: Journal of Obstetrics and Gynaecology Research
Ratko Delić, Mario Štefanović, Štefka Krivec, Vladimir Weber, Jakob Koren
OBJECTIVE: The aim of this study was to measure serum concentrations of human epididymis protein 4 (HE4) in premenopausal and postmenopausal women with benign adnexal tumors and compare HE4 levels with those of cancer antigen 125 (CA125) measured in the same samples. METHODS: In a retrospectively designed, monocentric study (Department of Gynecology & Obstetrics, General Hospital, Celje, Slovenia, EU), 147 women diagnosed with various benign adnexal tumors were included...
October 17, 2016: Wiener Klinische Wochenschrift
M Canis, R Botchorishvili, N Bourdel, C Chauffour, A-S Gremeau, B Rabischong, S Campagne, J-L Pouly, S Matsuzaki
No abstract text is available yet for this article.
October 14, 2016: Gynécologie, Obstétrique & Fertilité
Sungwook Chun, Hyun Jin Cho, Yong Il Ji
OBJECTIVE: To evaluate the change of ovarian reserve after unilateral laparoscopic ovarian cystectomy (LOC) in the early postoperative period between patients divided according to histologic diagnosis of cyst type. MATERIALS AND METHODS: Sixty-five patients who were undergoing unilateral LOC for benign ovarian disease were included in this study. All participants were divided into three groups according to histologic diagnosis: endometrioma (n=26), mature teratoma (n=24), and other benign cyst (n=15)...
October 2016: Taiwanese Journal of Obstetrics & Gynecology
Jong-Wook Seo, Dong-Yun Lee, Byung-Koo Yoon, DooSeok Choi
STUDY OBJECTIVE: Young age is a possible risk factor of endometriosis recurrence after surgery. However, the efficacy of postoperative medical treatment has not been well addressed in adolescents. The purpose of this study was to evaluate whether postoperative medical treatment is as effective in adolescents as it is in adults in the prevention of endometrioma recurrence. DESIGN: A retrospective cohort study SETTING: Samsung Medical Center, Seoul, Korea. PARTICIPANTS: This study included 176 reproductive-aged women who underwent conservative laparoscopic surgery for pathology-confirmed endometrioma...
October 12, 2016: Journal of Pediatric and Adolescent Gynecology
Atsushi Kiba, Kouji Banno, Megumi Yanokura, Mari Asada, Yusuke Nakayama, Daisuke Aoki, Tatsuya Watanabe
AIM: Micro ribonucleic acids (miRNAs) play an important pathological role in endometriosis. Leuprolide acetate, an analog of gonadotropin-releasing hormone, is widely used to treat endometriosis; however, the molecular mechanisms involved in endometriotic tissue regression remain unclear. We performed miRNA expression profiling of clinical ovarian endometrioma to obtain insight into the effects of leuprolide acetate treatment. METHODS: We obtained clinical samples from nine normal eutopic endometrium, eight ovarian endometriotic, and 12 leuprolide acetate-treated endometriotic tissues...
October 6, 2016: Journal of Obstetrics and Gynaecology Research
Sayantan Jana, Kasturi Chatterjee, Amlan K Ray, Pramathes DasMahapatra, Snehasikta Swarnakar
Endometriosis is characterized by the ectopic development of the endometrium which relies on angiogenesis. Although studies have identified the involvement of different matrix metalloproteinases (MMPs) in endometriosis, no study has yet investigated the role of MMP-2 in endometriosis-associated angiogenesis. The present study aims to understand the regulation of MMP-2 activity in endothelial cells and on angiogenesis during progression of ovarian endometriosis. Histological and biochemical data showed increased expressions of vascular endothelial growth factor (VEGF), VEGF receptor-2, cycloxygenase (COX)-2, von Willebrand factor along with angiogenesis during endometriosis progression...
2016: PloS One
Gurkan Bozdag, Pinar Calis, Dila Zengin, Atakan Tanacan, Sevilay Karahan
OBJECTIVE: To construct antral follicle count (AFC) nomogram of general population for every age and to compare our data with previous studies to assess whether available AFC nomograms present any geographical inconsistency. STUDY DESIGN: A prospective cross-sectional study was conducted to document AFC nomogram among women in 20-50 years with regular menstrual bleeding. Patients admitted with hirsutism, menstrual irregularity, diagnosis of current/history of endometrioma and hormonal drug use within the last 6 months were excluded...
September 20, 2016: European Journal of Obstetrics, Gynecology, and Reproductive Biology
Dingmin Yan, Xishi Liu, Sun-Wei Guo
Hyperinnervation in endometriosis is now well documented, but so far only a few neurotrophins have been identified. Since endometriotic stromal cells secrete thromboxane A2 (TXA2), we sought to determine whether TXA2, derived from endometriotic stromal cells, induces neurite outgrowth. Using primary sensory neurons derived from rat dorsal root ganglia (DRG) and ectopic endometrial stromal cells (EESCs) derived from human ovarian endometrioma tissues, we treated the primary neurons with different concentrations of U-46619, a stable TXA2 mimetic, and performed a neuronal growth assay...
September 29, 2016: Reproductive Sciences
R J Rodgers, G D Reid, J Tsaltas, C J Michael
No abstract text is available yet for this article.
November 2015: Journal of Minimally Invasive Gynecology
Joa Falcao-Junior, Soc De Paula, E C Fonseca, D G Zauli, G F Freitas, A L Silva-Filho, A T Carvalho, P Traiman
No abstract text is available yet for this article.
November 2015: Journal of Minimally Invasive Gynecology
S Oh, H Kim, C Y Hur
No abstract text is available yet for this article.
November 2015: Journal of Minimally Invasive Gynecology
D S Choi, J-W Seo, B-K Yoon, D-Y Lee
No abstract text is available yet for this article.
November 2015: Journal of Minimally Invasive Gynecology
C Exacoustos, G De Felice, A Sansone, L Lazzeri, E Zupi, Carlo C Di, C Nappi, F Petraglia
No abstract text is available yet for this article.
November 2015: Journal of Minimally Invasive Gynecology
M Mabrouk, A Pesci, C Zorzi, T Grassi, R Clarizia, A Stepniewska, M Scioscia, G Zamboni, M Ceccaroni
No abstract text is available yet for this article.
November 2015: Journal of Minimally Invasive Gynecology
L Muzii, A Besharat, V Di Donato, A Bianchi, I Palaia, A Musella, C Marchetti, P Benedetti Panici
No abstract text is available yet for this article.
November 2015: Journal of Minimally Invasive Gynecology
M Parsa
No abstract text is available yet for this article.
November 2015: Journal of Minimally Invasive Gynecology
Isabelle Streuli, Pietro Santulli, Sandrine Chouzenoux, Charles Chapron, Frédéric Batteux
We investigated whether serum osteopontin (OPN) levels are different according to specific phenotypes of adenomyosis and endometriosis. We conducted a prospective laboratory study in a university referral center for endometriosis between May 2005 and May 2013 and included 148 nonpregnant women, younger than 42 years, undergoing surgery for a benign gynecological condition and who had a preoperative pelvic magnetic resonance imaging (MRI). The presence of focal and/or diffuse adenomyosis was determined by pelvic MRI, and women were classified into 3 groups: no-adenomyosis (No-AM), isolated diffuse adenomyosis (DIF-AM), and focal adenomyosis with or without diffuse adenomyosis (FOC-AM)...
September 27, 2016: Reproductive Sciences
Aynur Ersahin, Onder Celik, Mustafa Acet, Suphan Ersahin, Tuba Acet, Duygu Kara Bozkurt, Yasemin Yavuz, Selcuk Ilhan
The aim of this study was to determine whether endometrioma resection alters most commonly defined endometrial metabolites, lactate (Lac), N-acetylaspartate (NAA), creatine 1 (Cr1), creatine 2 (Cr2), and choline (Cho) during the window of implantation. Twenty patients with uni- or bilateral endometrioma and 7 patients having nonendometriotic benign ovarian cyst were included. Midluteal phase magnetic resonance spectroscopy analysis of eutopic endometrium was performed before surgery. Second spectrum of endometrium was obtained 3 to 5 months after laparoscopic endometrioma resection...
September 27, 2016: Reproductive Sciences
I Motte, H Roman, B Clavier, F Jumeau, I Chanavaz-Lacheray, M Letailleur, B Darwish, N Rives
OBJECTIVE: Ovarian endometrioma ablation using plasma energy appears to be a valuable alternative to cystectomy, because it could spare underlying ovarian parenchyma resulting in high spontaneous and overall pregnancy rates. After initial postoperative decrease, anti-mullerian hormone (AMH) level progressively increases several months after ablation. The aim of our study was to assess the outcomes of in vitro fertilization (IVF) in women managed for ovarian endometriomas by ablation using plasma energy, when compared to those in women free of endometriosis...
September 21, 2016: Gynécologie, Obstétrique & Fertilité
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