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Endometrioma

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https://www.readbyqxmd.com/read/29471493/the-effect-of-pregnancy-on-endometriosis-facts-or-fiction
#1
Brigitte Leeners, Fabia Damaso, Nicole Ochsenbein-Kölble, Cindy Farquhar
BACKGROUND: It is not uncommon for women with endometriosis to be advised that becoming pregnant might be a useful strategy to manage their symptoms and reduce disease progression. Consequently, many women diagnosed with endometriosis and motivated to become pregnant, may also have expectations regarding improvement of symptoms and the disease. However, study results on the effect of pregnancy on endometriosis are controversial and pregnancy in women with endometriosis is not always associated with improved symptoms...
February 15, 2018: Human Reproduction Update
https://www.readbyqxmd.com/read/29456705/discrimination-of-malignant-transformation-from-benign-endometriosis-using-a-near-infrared-approach
#2
Naoki Kawahara, Yuki Yamada, Fuminori Ito, Wataru Hojo, Takuya Iwabuchi, Hiroshi Kobayashi
The aim of the present single-center retrospective study was to investigate the discrimination of malignant transformation from ovarian endometrioma (OE) using a near-infrared approach ex vivo . Cystic fluid samples were collected from patients with OE (n=34) and endometriosis-associated ovarian cancer (EAOC) (n=12). The light reflected from each sample of cystic fluid [change in luminance, Δl (cd/m2 ) = background luminance-cystic fluid luminance at 800 nm] was spectrally measured by a near-infrared CCD camera with band-path filter (800 nm)...
March 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29450853/endometriosis-clinical-features-mr-imaging-findings-and-pathologic-correlation
#3
REVIEW
Pietro Valerio Foti, Renato Farina, Stefano Palmucci, Ilenia Anna Agata Vizzini, Norma Libertini, Maria Coronella, Saveria Spadola, Rosario Caltabiano, Marco Iraci, Antonio Basile, Pietro Milone, Antonio Cianci, Giovanni Carlo Ettorre
OBJECTIVE: We illustrate the magnetic resonance imaging (MRI) features of endometriosis. BACKGROUND: Endometriosis is a chronic gynaecological condition affecting women of reproductive age and may cause pelvic pain and infertility. It is characterized by the growth of functional ectopic endometrial glands and stroma outside the uterus and includes three different manifestations: ovarian endometriomas, peritoneal implants, deep pelvic endometriosis. The primary locations are in the pelvis; extrapelvic endometriosis may rarely occur...
February 15, 2018: Insights Into Imaging
https://www.readbyqxmd.com/read/29439618/effect-of-prolonged-gnrh-agonist-downregulation-on-icsi-outcome-in-patients-with-endometriomas-of-less-than-5-cm-a-randomized-controlled-trial
#4
Ahmed Mohamed Maged, Hamsa Rashwan, Maryam Mahmoud, Akmal El-Mazny, Mona Farouk, Doaa S Belal, Heba M Marie
OBJECTIVE: To evaluate the effect of prolonged Gonadotropin releasing hormone (GnRH) agonist downregulation in patients with endometriomas of less than 5 cm on the outcome of the proceeding Intracytoplasmic sperm injection (ICSI) trial. METHODS: In a randomized controlled trial at a university teaching hospital, 90 patients indicated for ICSI and having unilateral single endometrioma of less than 5 cm in diameter were randomized into 2 groups. Group A (45 patients) received the standard long protocol; whereas group B (45 patients) received 3 consecutive Intramuscular (IM) injections of triptorelin 3...
January 1, 2018: Reproductive Sciences
https://www.readbyqxmd.com/read/29434846/co-existence-of-benign-gynecological-tumors-with-endometriosis-in-a-group-of-1-000-women
#5
Charoula Matalliotaki, Michail Matalliotakis, Panagiotis Ieromonachou, George N Goulielmos, Maria I Zervou, Aggelos Laliotis, Demetrios A Spandidos, Aydin Arici, Ioannis Matalliotakis
The purpose of this study was two-fold, first to investigate the association between endometriosis and the risk of benign gynecologic tumors and, secondly, to evaluate the distribution of endometrioma and ovarian cysts in women with endometriosis. The medical and pathological reports of 1,000 women with endometriosis were retrospectively reviewed. The incidence of ovarian cysts, uterine leiomyomas and adenomyosis, as well as the side of ovarian cysts were further compared. A total of 295 cases of endometriomas, 172 cases of adenomyosis, 173 cases of ovarian cysts and 89 cases of uterine leiomyomas were confirmed histologically in patients with endometriosis...
February 2018: Oncology Letters
https://www.readbyqxmd.com/read/29432902/anterior-focal-adenomyosis-and-bladder-deep-infiltrative-is-there-a-link
#6
Louis Marcellin, Pietro Santulli, Sara Bortolato, Cécile Morin, Anne Elodie Millisher, Bruno Borghese, Charles Chapron
STUDY OBJECTIVE: To evaluate the association between bladder deep infiltrating endometriosis (DIE) and anterior focal adenomyosis of the outer myometrium (aFAOM) diagnosed by preoperative magnetic resonance imaging (MRI). DESIGN: An observational, cross-sectional study using prospectively collected data (Canadian Task Force classification II-2). SETTING: Single university tertiary referral center. PATIENTS: All non-pregnant women less than 42-years-old who had undergone complete surgical exeresis of endometriotic lesions...
February 9, 2018: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/29420391/clinical-management-of-endometriosis
#7
Tommaso Falcone, Rebecca Flyckt
Endometriosis is a common and challenging condition of reproductive-aged women that carries a high individual and societal cost. The many molecular dissimilarities between endometriosis lesions and eutopic endometrium create difficulties in the development of new drug therapies and treatments. Surgery remains the gold standard for definitive diagnosis, but it must be weighed against the risks of surgical morbidity and potential decreases in ovarian reserve, especially in the case of endometriomas. Safe and effective surgical techniques are discussed within this article for various presentations of endometriosis...
February 5, 2018: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29418038/imaging-in-gynecological-disease-clinical-and-ultrasound-characteristics-of-endometrioid-ovarian-cancer
#8
F Moro, G Magoga, T Pasciuto, F Mascilini, M C Moruzzi, D Fischerova, L Savelli, S Giunchi, R Mancari, D Franchi, A Czekierdowski, W Froyman, D Verri, E Epstein, V Chiappa, S Guerriero, G F Zannoni, D Timmerman, G Scambia, L Valentin, A C Testa
OBJECTIVE: To describe the clinical and ultrasound characteristics of ovarian pure endometrioid carcinoma. METHODS: This is a retrospective multicenter study. From the International Ovarian Tumor Analysis (IOTA) database we identified 161 patients with a histological diagnosis of pure endometrioid carcinoma, who had undergone preoperative ultrasound examination by an experienced ultrasound examiner between 1999 and 2016. Another 78 patients with a histological diagnosis of pure endometrioid carcinoma were identified from the databases of the departments of gynecological oncology in the participating centers...
February 8, 2018: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29398419/the-endometrial-stem-cell-markers-notch-1-and-numb-are-associated-with-endometriosis
#9
Andreas N Schüring, Beatrice Dahlhues, Anna Korte, Ludwig Kiesel, Ulf Titze, Birthe Heitkötter, Christian Ruckert, Martin Götte
Previous studies reported increased expression of the notch pathway-associated protein Musashi-1 in endometriosis. This case-control study investigates an association of the endometrial stem cell markers notch-1 and numb with endometriosis. Fifty-one endometriosis patients and 76 controls were recruited in the IVF unit and tertiary endometriosis referral centre of a university hospital. All subjects underwent transcervical endometrial biopsy and diagnostic laparoscopy. Expression of endometrial notch-1 and numb was assessed by immunostaining and correlated with clinical data...
December 28, 2017: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/29385395/mirna-expression-pattern-differs-depending-on-endometriosis-lesion-type
#10
M E Haikalis, J M Wessels, N A Leyland, S K Agarwal, W G Foster
MicroRNA (miRNA), non-coding segments of RNA involved in post-transcriptional regulation of protein expression, are differentially expressed in eutopic endometrium of women with and without endometriosis compared to endometriotic lesions. However, endometriotic lesion types are known to be biochemically distinct and therefore hypothesized that miRNAs are differentially expressed in endometriomas compared to peritoneal and deep-infiltrating lesions. Therefore endometrial biopsies and ectopic implants from women (n = 38) undergoing laparoscopic surgery for chronic pelvic pain were collected...
January 29, 2018: Biology of Reproduction
https://www.readbyqxmd.com/read/29372161/menstrual-characteristics-in-korean-women-with-endometriosis-a-pilot-study
#11
Ji Yeon Han, Eun Ji Lee, Byung Chul Jee, Seok Hyun Kim
Objective: This study aimed to determine whether the menstrual characteristics are different in Korean women with or without ovarian endometrioma. Methods: We selected 95 premenopausal women aged below 39 years who underwent laparoscopic surgery for ovarian endometrioma (n=46) or other benign ovarian tumors (n=49) between April 2016 and February 2017. We excluded those with uterine diseases that could potentially affect the menstrual characteristics and those on anticoagulants or hormonal medication...
January 2018: Obstetrics & Gynecology Science
https://www.readbyqxmd.com/read/29372157/clinical-experience-of-long-term-use-of-dienogest-after-surgery-for-ovarian-endometrioma
#12
Anjali Chandra, A Mi Rho, Kyungah Jeong, Taeri Yu, Ji Hyun Jeon, So Yun Park, Sa Ra Lee, Hye-Sung Moon, Hye Won Chung
Objective: Endometriosis is a common and recurring gynecologic disease which have afflicting females of reproductive age. We investigated the efficacy of long-term, post-operative use of dienogest for ovarian endometrioma. Methods: We studied 203 patients who had undergone laparoscopic or robotic surgery for ovarian endometrioma, and were administrated dienogest 2 mg/day beginning in July of 2013, and continuing. We evaluated side effects of dienogest and ultrasonography was performed every 6 months to detect potential recurrence of endometrioma (2 cm) in these post-surgical patients...
January 2018: Obstetrics & Gynecology Science
https://www.readbyqxmd.com/read/29359457/the-levonorgestrel-releasing-intrauterine-system-is-associated-with-a-reduction-in-dysmenorrhoea-and-dyspareunia-a-decrease-in-ca-125-levels-and-an-increase-in-quality-of-life-in-women-with-suspected-endometriosis
#13
Nese Yucel, Erdem Baskent, Burcin Karamustafaoglu Balci, Gokhan Goynumer
BACKGROUND AND AIMS: The aim of this study was to investigate the effectiveness of a levonorgestrel-releasing intrauterine device (LNG-IUS) in the symptomatic relief of pain in women with endometriosis and additionally, to assess the changes in women's life quality and serum cancer antigen (CA) 125 levels. MATERIALS AND METHODS: All women who had an LNG-IUS inserted for the treatment of dysmenorrhea, chronic pelvic pain or both for more than six months over a two-year period were included in the study...
January 23, 2018: Australian & New Zealand Journal of Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/29353008/the-isolated-ovarian-endometrioma-a-history-between-myth-and-reality
#14
Caterina Exacoustos, De Felice Giovanna, Alessandra Pizzo, Giulia Morosetti, Lucia Lazzeri, Gabriele Centini, Emilio Piccione, Errico Zupi
STUDY OBJECTIVE: To assess the association between ovarian endometriomas detectable at transvaginal ultrasound (TVS) and other specific extra-ovarian lesions including adhesions, deep infiltrating endometriosis, and adenomyosis. DESIGN: Retrospective observational study (Canadian Task Force classification II-2). SETTING: Two university hospitals. PATIENTS: 255 symptomatic women with at least one ovarian endometrioma found on ultrasound after presentation with pain or irregular menstruation...
January 15, 2018: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/29344847/the-effect-of-surgical-management-of-endometrioma-on-the-ivf-icsi-outcomes-when-compared-with-no-treatment-a-systematic-review-and-meta-analysis
#15
M Nickkho-Amiry, R Savant, K Majumder, E Edi-O'sagie, M Akhtar
OBJECTIVE: To assess the impact of surgical management of endometrioma on the outcome of assisted reproduction treatment (ART). DESIGN: A systematic review and meta-analysis. SETTING: Department of reproductive medicine at teaching university hospital, UK. PATIENTS: Subfertile women with endometrioma undergoing ART. INTERVENTIONS: Surgical removal of endometrioma or expectant management. MAIN OUTCOME MEASURES: Clinical pregnancy rate, pregnancy rate, live birth rate, number of oocytes retrieved and number of embryos available and ovarian response to gonadotrophins...
January 17, 2018: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29334789/circular-rna-expression-in-ovarian-endometriosis
#16
Licong Shen, Yu Zhang, Wenjun Zhou, Zheng Peng, Xiaxia Hong, Yi Zhang
AIM: Circular RNAs (circRNAs) with miRNA response elements (MREs) could function as competing endogenous RNA (ceRNA) in regulating gene expression. This study was carried out to identify the expression profile and role of circRNAs in endometriosis. MATERIALS & METHODS: Microarray assay was performed in four paired ovarian endometriomas and eutopic endometrium, followed by quantitative real-time RT-PCR in 24 paired samples. Bioinformatical algorithms were used to predict MREs, as well as ceRNA and KEGG pathway analysis...
January 16, 2018: Epigenomics
https://www.readbyqxmd.com/read/29300932/endometrial-stromal-cell-attachment-and-matrix-homeostasis-in-abdominal-wall-endometriomas
#17
Hiroko Itoh, Haruta Mogami, Laurice Bou Nemer, Larry Word, David Rogers, Rodney Miller, R Ann Word
STUDY QUESTION: How does progesterone alter matrix remodeling in abdominal wall endometriomas compared with normal endometrium? SUMMARY ANSWER: Progesterone may prevent attachment of endometrial cells to the abdominal wall, but does not ameliorate abnormal stromal cell responses of abdominal wall endometriomas. WHAT IS KNOWN ALREADY: Menstruation is a tightly orchestrated physiologic event in which steroid hormones and inflammatory cells cooperatively initiate shedding of the endometrium...
December 28, 2017: Human Reproduction
https://www.readbyqxmd.com/read/29290906/cesarean-section-scar-endometrioma-a-case-report-and-review-of-the-literature
#18
Madison Kocher, Andrew Hardie, Amanda Schaefer, Thomas McLaren, Mark Kovacs
Endometriomas can occur after any surgery where there is endometrial manipulation, and there are a number of reports of endometriomas developing in the abdominal wall at the site of the Pfannenstiel incision following Cesarean-section. Although this is ultimately a histopathologically-confirmed diagnosis, preoperative imaging including ultrasound, computed tomography, and magnetic resonance imaging may be helpful in the diagnosis and assessment. We report a pathology-confirmed case of Cesarean-section endometrioma with a classic, clinical presentation and imaging findings on computed tomography...
December 2017: Journal of Radiology Case Reports
https://www.readbyqxmd.com/read/29285999/the-clinical-characteristics-and-surgical-approach-of-abdominal-wall-endometriosis-a-case-series-of-14-women
#19
Faik Tatli, Orhan Gozeneli, Hacer Uyanikoglu, Ali Uzunkoy, Huseyin Cahit Yalcın, Abdullah Ozgonul, Osman Bardakci, Adnan Incebiyik, Muhammet Emin Guldur
Abdominal wall endometriosis (AWE) is a rare form of endometriosis that usually develops in the scar after cesarean section (CS). Recently, the occurrence of AWE has been increasing together with the increase of CS incidence. AWE can be clinically misdiagnosed as hernia, lipoma, or hematoma. Here we retrospectively analyzed the clinical aspects of AWE and surgical approach in 14 patients from a tertiary hospital, who were treated by surgery, between 2012 and 2017. The mean age was 32.71 ± 8.61 years (range: 19-45)...
December 29, 2017: Bosnian Journal of Basic Medical Sciences
https://www.readbyqxmd.com/read/29285022/recommendations-for-the-surgical-treatment-of-endometriosis-part-1-ovarian-endometrioma
#20
Ertan Saridogan, Christian M Becker, Anis Feki, Grigoris F Grimbizis, Lone Hummelshoj, Joerg Keckstein, Michelle Nisolle, Vasilios Tanos, Uwe A Ulrich, Nathalie Vermeulen, Rudy Leon De Wilde
Study question: What does this document on the surgical treatment of endometriosis jointly prepared by the European Society for Gynaecological Endoscopy (ESGE), ESHRE, and the World Endometriosis Society (WES) provide? Summary answer: This document provides recommendations covering technical aspects of different methods of surgery for endometriomas in women of reproductive age. What is already known: Endometriomas (ovarian endometriotic cysts) are a commonly diagnosed form of endometriosis, owing to the relative ease and accuracy of ultrasound diagnosis...
2017: Gynecological Surgery
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