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https://www.readbyqxmd.com/read/28314166/effects-of-long-term-postoperative-dienogest-use-for-treatment-of-endometriosis-on-bone-mineral-density
#1
Jong-Wook Seo, Dong-Yun Lee, Byung-Koo Yoon, DooSeok Choi
OBJECTIVE: This study was conducted to evaluate the effects of long-term postoperative dienogest (DNG) use for the treatment of endometriosis on bone mineral density (BMD). STUDY DESIGN: Sixty reproductive-aged women who underwent conservative surgery for endometriomas and received postoperative DNG (2mg/day) for at least 12 months to prevent recurrence were analyzed. BMD was measured before and after DNG treatment by using dual energy X-ray absorptiometry, and changes in BMD were evaluated...
March 6, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28290209/plasma-brain-derived-neurotrophic-factor-in-women-with-pelvic-pain-a-potential-biomarker-for-endometriosis
#2
Ana L Rocha, Erica L Vieira, Márcia C Ferreira, Laura M Maia, Antonio L Teixeira, Fernando M Reis
AIM: To test whether plasma BDNF levels are useful to predict the presence of endometriosis in women with pelvic pain. PATIENTS & METHODS: Prospective cross-sectional study including 67 consecutive women aged 24-49 years, scheduled for laparoscopy due to chronic pelvic pain. Preoperative plasma samples were assayed for BDNF using a commercial enzyme immunoassay. RESULTS: Women with ovarian endometrioma had higher preoperative plasma BDNF (1063 ± 157 pg/ml) compared with women with other benign ovarian tumors (537 ± 131 pg/ml, F = 2...
March 14, 2017: Biomarkers in Medicine
https://www.readbyqxmd.com/read/28271698/ovarian-cancer-in-endometriosis-clinical-and-molecular-aspects-an-update
#3
Rachel Ruderman, Mary E Pavone
While endometriosis is a benign condition, the presence of endometriosis has been associated with the development of several types of cancers, including ovarian. Endometriomas, or ovarian endometriotic cysts, are found in 17-44% of patients with endometriosis, and may be a common precursor lesions to ovarian cancer. Endometriosis associated ovarian cancer is especially prominent in endometrioid and clear cell ovarian tumor histological subtypes. Several common pathways linking endometriosis and ovarian cancer have been elucidated, including the dominance of certain cytokines, oxidative stress, and a hyper-estrogenic hormonal milieu, which propagate both endometriosis and endometriosis associated ovarian cancer...
March 7, 2017: Minerva Ginecologica
https://www.readbyqxmd.com/read/28263049/is-there-a-role-of-single-port-laparoscopy-in-the-treatment-of-endometriosis
#4
Angelos Daniilidis, Kimon Chatzistamatiou, Efstratios Assimakopoulos
BACKGROUND: Endometriosis is among the most common benign gynecological conditions, and it affects 6-15% of women of reproductive. During recent decades, minimally invasive surgical techniques, and especially laparoscopy, have gained significant ground concerning the treatment of gynecological disorders. To date, laparoscopy is considered the gold standard for the diagnosis and treatment of endometriosis. METHODS: Available papers in Pub Med and Scopus data base, written in English language have been used for the current narrative review...
March 6, 2017: Minerva Ginecologica
https://www.readbyqxmd.com/read/28254227/unexpected-epithelial-ovarian-cancers-arising-from-presumed-endometrioma-a-10-year-retrospective-analysis
#5
Hsin-Hong Kuo, Chen-Ying Huang, Shir-Hwa Ueng, Kuan-Gen Huang, Chyi-Long Lee, Chih-Feng Yen
OBJECTIVE: To evaluate the incidence and prognosis of unexpected epithelial ovarian cancers (EOCs) occurring in presumed benign endometrioma. MATERIALS AND METHODS: Patients who underwent primary surgery at Chang Gung Memorial Hospital between November 2003 and October 2013 were searched with the Systematized Nomenclature of Medicine code followed by chart review. RESULTS: The incidence of unexpected EOCs in presumed ovarian endometrioma was 0...
February 2017: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28246564/false-positive-findings-on-i-131-wbs-and-spect-ct-in-patients-with-history-of-thyroid-cancer-case-series
#6
Zeina C Hannoush, Juan D Palacios, Russ A Kuker, Sabina Casula
Introduction. Although whole body scan (WBS) with I-131 is a highly sensitive tool for detecting normal thyroid tissue and metastasis of differentiated thyroid cancer (DTC), it is not specific. Additional information, provided by single photon emission computed tomography combined with X-ray computed tomography (SPECT/CT) and by the serum thyroglobulin level, is extremely useful for the interpretation of findings. Case Presentation. We report four cases of false positive WBS in patients with DTC: ovarian uptake corresponding to an endometrioma, scrotal uptake due to a spermatocele, rib-cage uptake due to an old fracture, and hepatic and renal uptake secondary to a granuloma and simple cyst, respectively...
2017: Case Reports in Endocrinology
https://www.readbyqxmd.com/read/28240000/endometriosis-and-ovarian-cancer-an-integrative-review-endometriosis-and-ovarian-cancer
#7
Aline Veras Morais Brilhante, Kathiane Lustosa Augusto, Manuela Cavalcante Portela, Luiz Carlos Gabriele Sucupira, Luiz Adriano Freitas Oliveira, Ana Juariana Magalhães Veríssimo Pouchaim, Lívia Rocha Mesquita Nóbrega, Thaís Fontes de Magalhães, Leonardo Robson Pinheiro Sobreira
Despite being initially considered a benign disease, it is widely thought nowadays that endometriosis and especially ovarian endometriomas are neoplastic conditions with the potential to become malignant. This review was conducted to summarize, in a concise and systematic manner, the available scientific data relating endometriosis to ovarian cancer, published in the past five years. After reading abstracts and applying our predefined inclusion and exclusion criteria, a final list of 11 scientific papers was obtained and subjected to review...
January 1, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28218772/diagnosis-and-management-of-abdominal-wall-endometriosis-a-systematic-review-and-clinical-recommendations
#8
REVIEW
Noah B Rindos, Suketu Mansuria
Importance: Abdominal wall endometriosis (AWE) is a rare but easily treated cause of pain in women, especially those who have undergone cesarean deliveries. Objective: This article reviews the diagnosis and management of AWE, a condition that generally develops after surgery but may arise spontaneously. We present a systematic review of the existing literature on AWE, as well as our clinical recommendations for medical and surgical management. Evidence Acquisition: We searched PubMed and other databases using the search criteria "abdominal wall endometriosis," "abdominal wall endometriomas," and "abdominal wall mass...
February 2017: Obstetrical & Gynecological Survey
https://www.readbyqxmd.com/read/28217673/in-vitro-fertilization-outcomes-in-women-with-surgery-induced-diminished-ovarian-reserve-after-endometrioma-operation-comparison-with-diminished-ovarian-reserve-without-ovarian-surgery
#9
Su Been Hong, Na Ra Lee, Seul Ki Kim, Hoon Kim, Byung Chul Jee, Chang Suk Suh, Seok Hyun Kim, Young Min Choi
OBJECTIVE: To compare the in vitro fertilization (IVF) outcomes between women with diminished ovarian reserve (DOR) after endometrioma operation and women with DOR without ovarian surgery. METHODS: This retrospective case-control study included 124 women aged under 40 and had DOR (serum anti-Müllerian hormone level <1.1 ng/mL or antral follicle count ≤6). They participated in fresh first and/or second IVF cycles between March in 2010 and December in 2015. Basal characteristics and IVF outcomes were compared between 47 cycles (32 women) with surgery-induced DOR and 119 cycles (92 women) with DOR without ovarian surgery...
January 2017: Obstetrics & Gynecology Science
https://www.readbyqxmd.com/read/28210515/cystic-endometrioma-with-coexisting-fibroma-originating-in-a-supernumerary-ovary-in-the-rectovaginal-pouch
#10
Daiki Ogishima, Asumi Sakaguchi, Hiroko Kodama, Kanako Ogura, Ayako Miwa, Yayoi Sugimori, Shozo Matuoka, Toshiharu Matsumoto
A supernumerary ovary is an exceedingly rare disorder, in which the structure containing ovarian tissue is located at some distance from the normally placed ovary. 16 cases of endometriosis or tumors originating in a supernumerary ovary have been published in the English literature, but no case of coexisting endometriosis and a tumor has been published. We present the case of a 40-year-old female with cystic endometrioma with coexisting fibroma originating in a supernumerary ovary in the rectovaginal pouch...
2017: Case Reports in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28209488/postoperative-maintenance-levonorgestrel-releasing-intrauterine-system-and-endometrioma-recurrence-a%C3%A2-randomized-controlled-study
#11
Yi-Jen Chen, Teh-Fu Hsu, Ben-Shian Huang, Hsiao-Wen Tsai, Yen-Hou Chang, Peng-Hui Wang
BACKGROUND: According to 3 randomized trials, the levonorgestrel-releasing intrauterine system significantly reduced recurrent endometriosis-related pelvic pain at postoperative year 1. Only a few studies have evaluated the long-term effectiveness of the device for preventing endometrioma recurrence, and the effects of a levonorgestrel-releasing intrauterine system as a maintenance therapy remain unclear. OBJECTIVE: The objective of the study was to evaluate whether a maintenance levonorgestrel-releasing intrauterine system is effective for preventing postoperative endometrioma recurrence...
February 15, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28186620/an-update-on-the-diagnosis-surgical-management-and-fertility-outcomes-for-women-with-endometrioma
#12
REVIEW
Ryan Cranney, George Condous, Shannon Reid
Endometriosis is estimated to affect up to 50% of infertile women, and severity of endometriosis stage appears to correlate with reduced fertility. Ovarian endometriomas are found in up to 44% of women with endometriosis, and are significantly associated with the presence of pelvic deep infiltrating endometriosis, ovarian adhesions, and pouch of Douglas obliteration. Through the use of MEDLINE and PubMed databases, we conducted a literature review of all available research related to the diagnosis, surgical management and fertility outcomes for women with endometrioma...
February 10, 2017: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/28160605/increased-ipsilateral-uterine-artery-vascular-resistance-in-women-with-ovarian-endometrioma
#13
Miyoko Waratani, Taisuke Mori, Fumitake Ito, Yukiko Tanaka, Akemi Koshiba, Akiko Takahata, Jo Kitawaki
AIM: The aim of this study was to elucidate whether the presence of an ovarian endometrioma is associated with impaired vascular flow. We investigated changes in vascular flow on the ipsilateral and contralateral side of the endometrioma, before and after surgery. METHODS: This prospective case-control study included 144 women (ovarian endometrioma [n = 40], endometriosis without ovarian endometrioma [n = 33], non-endometriotic ovarian cyst [n = 17], and normal pelvis [n = 54])...
February 3, 2017: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/28150406/preoperative-assessment-of-factors-associated-with-difficulty-in-performing-total-laparoscopic-hysterectomy
#14
Ako Saito, Tetsuya Hirata, Kaori Koga, Masashi Takamura, Shinya Fukuda, Kazuaki Neriishi, Gia Pastorfide, Miyuki Harada, Yasushi Hirota, Osamu Wada-Hiraike, Tomoyuki Fujii, Yutaka Osuga
AIM: Our objective was to determine the preoperative factors associated with difficulty in total laparoscopic hysterectomy (TLH). METHODS: This retrospective clinical study included 157 patients who underwent TLH for leiomyoma or adenomyosis between 2009 and 2013. All patients underwent magnetic resonance imaging (MRI) before surgery. We categorized patients as 'difficult' if the operation time was > 243 min, if total blood loss was > 500 mL, or if conversion to laparotomy was necessary...
February 2017: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/28139522/ovarian-fibrosis-a-phenomenon-of-concern
#15
REVIEW
Feng Zhou, Li-Bing Shi, Song-Ying Zhang
OBJECTIVE: Ovarian fibrosis is characterized by excessive proliferation of ovarian fibroblasts and deposition of extracellular matrix (ECM) and it is one of the principal reasons for ovarian dysfunction. This review aimed to investigate the pathogenetic mechanism of ovarian fibrosis and to clarify the relationship between ovarian diseases and fibrosis. DATA SOURCES: We searched PubMed for English language articles published up to November 2016. The search terms included ovarian fibrosis OR fibrosis, ovarian chocolate cyst OR ovarian endometrioma, polycystic ovarian syndrome (PCOS), premature ovarian failure, ECM, matrix metalloproteinases (MMPs), tissue inhibitors of matrix metalloproteinases (TIMPs), transforming growth factor-beta 1 (TGF-β1), connective tissue growth factor (CTGF), peroxisome proliferator-activated receptor gamma (PPAR-γ), vascular endothelial growth factor (VEGF), endothelin-1 (ET-1), and combinations of these terms...
February 5, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28118296/malignancy-risk-of-sonographically-benign-appearing-purely-solid-adnexal-masses-in-asymptomatic-postmenopausal-women
#16
Juan Luis Alcazar, Maria Angela Pascual, Reyes Marquez, Silvia Ajossa, Leire Juez, Betlem Graupera, Alba Piras, Lourdes Hereter, Stefano Guerriero
OBJECTIVE: To assess the natural history of benign appearing purely solid ovarian lesions in asymptomatic postmenopausal women. METHODS: Retrospective observational cohort study comprising 99 women (mean age, 58.2 years, ranging from 50 to 77 years) diagnosed as having a purely solid ovarian lesion at transvaginal ultrasound between April 2001 and October 2015. Inclusion criteria were as follows: asymptomatic postmenopausal women with a well-defined purely solid ovarian lesion with International Ovarian Tumor Analysis color score 1 or 2, without ascites and/or signs of carcinomatosis...
January 23, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28109703/investigation-of-anogenital-distance-as-a-diagnostic-tool-in-endometriosis
#17
Maria L Sánchez-Ferrer, Jaime Mendiola, Raquel Jiménez-Velázquez, Laura Cánovas-López, Shiana Corbalán-Biyang, Ana I Hernández-Peñalver, Ana Carmona-Barnosi, Ana B Maldonado-Cárceles, Maria T Prieto-Sánchez, Francisco Machado-Linde, Anibal Nieto, Alberto M Torres-Cantero
An association between anogenital distance (AGD) and endometriosis has been reported, suggesting that AGD may be a useful clinical tool in endometriosis. The predictive ability of AGD of women in discriminating presence and type of endometriosis was examined. A case-control study was conducted at the University Hospital 'Virgen de la Arrixaca', Murcia, Spain, between 2014 and 2015. A total of 114 participants diagnosed with endometriosis using ultrasound findings and 105 controls were recruited. Two AGD measurements were obtained: one from the anterior clitoral surface to the upper verge of the anus (AGDAC), and another one from the posterior fourchette to the upper verge of the anus (AGDAF)...
January 10, 2017: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/28099732/the-impact-of-laparoscopic-cystectomy-on-ovarian-reserve-in-patients-with-unilateral-and-bilateral-endometrioma
#18
Abolfazl Mehdizadeh Kashi, Shahla Chaichian, Shideh Ariana, Masoumeh Fazaeli, Yousef Moradi, Mandana Rashidi, Zahra Najmi
OBJECTIVE: To evaluate the effects of laparoscopic cystectomy on serum anti-Müllerian hormone (AMH) level as a marker of ovarian reserve in patients with endometrioma. METHODS: A prospective observational study enrolled patients aged younger than 40 years who were referred to a tertiary center in Tehran, Iran, between January 1, 2013 and December 31, 2014 to undergo laparoscopic cystectomy for ovarian endometriomas at least 30 mm in diameter, or regardless of size for patients with infertility, dysmenorrhea, dyspareunia, or dyschezia...
February 2017: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/28090460/efficacy-and-safety-of-dienogest-in-patients-with-endometriosis-a-single-center-observational-study-over-12-months
#19
So Yun Park, Sung Hoon Kim, Hee Dong Chae, Chung-Hoon Kim, Byung Moon Kang
OBJECTIVE: To evaluate the efficacy and safety of dienogest treatment in patients who had received dienogest for 12 months or more to treat endometriosis. METHODS: We analyzed the clinical data of 188 women with endometriosis who had been treated with 2 mg of dienogest once a day for 12 months or more at a single institute. We evaluated changes in endometriosis-associated pain and endometrioma size, recurrence rate, and adverse events following dienogest administration...
December 2016: Clinical and Experimental Reproductive Medicine
https://www.readbyqxmd.com/read/28089684/the-impact-of-cystectomy-on-ovarian-reserve-a-review-of-the-literature
#20
REVIEW
Roa Alammari, Michelle Lightfoot, Hye-Chun Hur
Ovarian cysts are common in the reproductive age. Pathological cysts such as endometriomas and dermoids often require surgical intervention if symptomatic. Laparoscopic cystectomy is the first line treatment for these cysts, and is associated with better pain control and less recurrence than drainage or cyst ablation procedures. There has been an emerging concern about the effect of ovarian cystectomy on ovarian reserve with some evidence of short term and long term reduction in ovarian reserve. Certain cyst characteristics (endometrioma pathology, large cyst size, bilateral presentation) are associated with greater decline in ovarian reserve after cystectomy...
January 9, 2017: Journal of Minimally Invasive Gynecology
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