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Eloise G Harrison, Jennifer L Keating, Prue E Morgan
INTRODUCTION: Restless legs syndrome (RLS) is a sensorimotor disorder characterised by an uncomfortable urge to move the legs. Management is primarily pharmacological. Effects for non-pharmacological, non-surgical options are published but lack systematic examination. OBJECTIVES: To synthesise results of non-pharmacological/non-surgical treatment compared to no-treatment controls or alternative treatment for RLS on any relevant outcome. METHODS: Databases and reference lists of reviews were searched for randomised controlled trials (RCTs) comparing non-pharmacological treatment to alternative or no treatment controls for idiopathic RLS...
March 21, 2018: Disability and Rehabilitation
Feng Liu, Priyatanu Roy, Qi Shao, Chunlan Jiang, Jeunghwan Choi, Connie Chung, Dushyant Mehra, Dr John Bischof
Atrial fibrillation affects millions of people in the US. Focal therapy is an attractive treatment for atrial fibrillation that avoids the debilitating effects of drugs for disease control. Perhaps the most widely used focal therapy for atrial fibrillation (AF) is heat-based radiofrequency (heating), although cryotherapy (cryo) is rapidly replacing it due to a reduction in side effects and positive clinical outcomes. A third focal therapy, irreversible electroporation (IRE), is also being considered. This study was designed to help guide treatment thresholds and compare mechanism of action across heating, cryo, and IRE...
February 17, 2018: Journal of Biomechanical Engineering
Austin B Hopper, Ajay P S Sandhu, J Kellogg Parsons, Brent Rose, John P Einck
Purpose: Cryotherapy is an option for the primary treatment of localized prostate cancer, along with radical prostatectomy, external beam radiation therapy, and brachytherapy. Although it is known that local recurrence can occur in >20% of patients treated with primary cryotherapy, unfortunately there is a paucity of data on later salvage treatments. The use of external beam radiation therapy is an attractive option after cryotherapy failure, but there is little data on its efficacy and toxicity...
January 2018: Advances in Radiation Oncology
Jill Alexander, Jim Richards, Obed Attah, Sam Cheema, Joanna Snook, Chloe Wisdell, Karen May, James Selfe
Delayed effects of a 20-min crushed ice application on knee joint position sense assessed by a functional task during a re-warming period. INTRODUCTION: The effect of cryotherapy on joint positioning presents conflicting debates as to whether individuals are at an increased risk of injury when returning to play following cryotherapy application at the lower limb. OBJECTIVES: The aim of this study was to investigate whether a 20 min application of crushed ice at the knee affects knee joint kinematics immediately post and up to 20 mins post ice removal, during a small knee bend...
March 6, 2018: Gait & Posture
Jacey L Janz Vernoski, Jack R Bjorkland, Talia J Kramer, Steven T Oczak, Alexandra L Borstad
Proprioception may be the least well measured of all contributors to the neural control of movement. New precise, reliable measures of proprioception are needed for clinical diagnosis of impairment, and to measure outcomes of proprioceptive training. The purpose of this simple, non-invasive method is to temporarily knockdown upper limb proprioception in healthy adults, to an extent that would be useful in the development and testing of upper limb proprioception measures. Knockdown models have two main advantages over studying humans with impaired proprioception: participant availability and the ability to control the extent of impairment across participants...
March 3, 2018: Journal of Visualized Experiments: JoVE
A Gevorgyan, J-F Hétet, M Robert, V Duchattelle-Dussaule, L Corno, I Boulay, H Baumert
OBJECTIVE: To study the oncologic and functional results of salvage cryotherapy after failure of external radiotherapy and brachytherapy. MATERIALS AND METHODS: Patients treated by total salvage cryotherapy (3rd generation) in 2 centers (Groupe Hospitalier Saint-Joseph in Paris and Clinique Jule-Verne Nantes) in between January 2008 and April 2016 were included. The biochemical recurrence-free survival (BRFS) was calculated using the Phoenix criteria (PSA>nadir+2ng/mL)...
March 15, 2018: Progrès en Urologie
Chin-Yu Lee, Tao-Hsin Tung, Chia-Yu Liu, Shu-Hui Wang, Ching-Chi Chi
BACKGROUND AND OBJECTIVE: Local anesthetic cream (LAC) has been used for analgesia in various procedures. However, the analgesic effect of LAC in cryotherapy for warts is unclear. We aimed to evaluate the effects of LAC in cryotherapy for warts. MATERIAL AND METHODS: We conducted a systematic review and meta-analysis of randomized controlled trials (RCTs) on the effects of LAC in cryotherapy for warts. We searched MEDLINE, CENTRAL, and EMBASE on 31 March 2017 for relevant RCTs...
March 2018: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
Jun Yeong Park, Bok Won Park, Eun Byul Cho, Eun Joo Park, Kwang Ho Kim, Kwang Joong Kim
BACKGROUND: Diphenylcyclopropenone (DPCP) immunotherapy for viral warts has been used for many years, but no studies have analyzed the treatment effects of DPCP alone, without the use of conventional therapy before immunotherapy. OBJECTIVES: We evaluated clinical efficacy of DPCP monotherapy compared to cryotherapy and pulsed dye laser (PDL) therapy. We also assessed the impact of initial sensitization on clinical response. METHODS: We retrospectively analyzed the medical records of 250 patients with multiple viral warts between January 2008 and December 2015...
March 1, 2018: Journal of Cutaneous Medicine and Surgery
Reza M Robati, Morteza Ghasemi-Pour
Cherry angioma (CA) is one of the most common types of acquired vascular proliferation of the skin [1]. The most commonly recommended treatment modalities in the past have been electrosurgery and cryotherapy. These treatment modalities usually show acceptable cosmetic results with minimal discomfort [2,3]. However, there is no study in the literature that compares these treatment modalities. Herein, we plan to assess the efficacy and safety of cryotherapy versus electrosurgery in the treatment of cherry angioma...
March 10, 2018: Journal of the European Academy of Dermatology and Venereology: JEADV
Prashanthi N Thota, Zubin Arora, John A Dumot, Gary Falk, Tanmayee Benjamin, John Goldblum, Sunguk Jang, Rocio Lopez, John J Vargo
BACKGROUND AND AIMS: Endoscopic ablation therapy has become the mainstay of treatment of Barrett's associated dysplasia and intramucosal cancer (IMC). The widely available techniques for ablation are radiofrequency ablation (RFA) and cryotherapy. Our aim was to compare eradication rates of metaplasia and dysplasia with both these modalities. PATIENTS AND METHODS: Retrospective review of prospectively collected database of patients who underwent endoscopic therapy for Barrett's dysplasia or IMC from 2006 to 2011 was performed...
March 9, 2018: Digestive Diseases and Sciences
Martha Carmona Lorduy, Jonathan Harris Ricardo, Yurtiza Hernández Arenas, Wanda Medina Carmona
The human papillomavirus (HPV) has an affinity for squamous cells of stratified keratinized epithelium, thus affecting the lower genital, nasal, and oral tracts. In the oral cavity, HPV is associated with pathoses such as the verruca vulgaris (common wart), squamous cell papilloma, condyloma acuminatum (venereal wart), and focal epithelial hyperplasia (Heck disease). Among the treatments available for these lesions are cryotherapy, electrosurgery, surgical removal, laser therapy, and trichloroacetic acid (TCA)...
March 2018: General Dentistry
Karen A Monsen, Teresa J Kelechi, Marion E McRae, Michelle A Mathiason, Karen S Martin
BACKGROUND: The growth and diversification of nursing theory, nursing terminology, and nursing data enable a convergence of theory- and data-driven discovery in the era of big data research. Existing datasets can be viewed through theoretical and terminology perspectives using visualization techniques in order to reveal new patterns and generate hypotheses. The Omaha System is a standardized terminology and metamodel that makes explicit the theoretical perspective of the nursing discipline and enables terminology-theory testing research...
March 2018: Nursing Research
P J Toliman, J M Kaldor, S N Tabrizi, A J Vallely
The estimated cervical cancer burden is over ten-fold greater in low- and middle-income countries (LMICs) than in high-income countries. This health gap is thought to be primarily due to limited access to effective screening and treatment programs for cervical pre-cancer and cancer in such settings. The World Health Organization advocates a policy of 'screen and treat' approach to cervical screening in LMICs and subsequently visual inspection of the cervix with acetic acid (VIA) or Lugo's iodine (VILI), followed by ablative cervical cryotherapy if indicated, and this policy has been implemented in many high-burden settings...
February 28, 2018: Climacteric: the Journal of the International Menopause Society
Karan Madan, Anant Mohan, Ritesh Agarwal, Vijay Hadda, Gopi C Khilnani, Randeep Guleria
Background: There is a lack of contemporaneous data on the practices of flexible bronchoscopy in India. Aim: The aim of the study was to study the prevalent practices of flexible bronchoscopy across India. Methods: The "Indian Bronchoscopy Survey" was a 98-question, online survey structured into the following sections: general information, patient preparation and monitoring, sedation and topical anesthesia, procedural/technical aspects, and bronchoscope disinfection/staff protection...
March 2018: Lung India: Official Organ of Indian Chest Society
Agata Stanek, Armand Cholewka, Tomasz Wielkoszyński, Ewa Romuk, Aleksander Sieroń
Objective: The aim of the study was to estimate the impact of whole-body cryotherapy (WBC) on cardiovascular risk factors in patients with ankylosing spondylitis (AS). Material and Methods: We investigated the effect of WBC with subsequent kinesiotherapy on markers of inflammation, oxidative stress, lipid profile, and atherosclerosis plaque in male AS patients (WBC group). To assess the disease activity, the BASDAI and BASFI were also calculated. The results from the WBC group were compared with results from the kinesiotherapy (KT) group...
2018: Mediators of Inflammation
Elena V Petrova, Hans Peter Brecht, Massoud Motamedi, Alexander A Oraevsky, Sergey A Ermilov
The objective of this study is to demonstrate in vivo the feasibility of optoacoustic temperature imaging during cryotherapy of prostate cancer. We developed a preclinical prototype of optoacoustic temperature imager that included pulsed optical excitation at 805-nm wavelength, a modified clinical transrectal ultrasound probe, parallel data acquisition system, image processing and visualization software. Cryotherapy of a canine prostate was performed in vivo using a commercial clinical system Cryocare CS with an integrated ultrasound imaging...
February 26, 2018: Physics in Medicine and Biology
Kavel Visrodia, Liam Zakko, Siddharth Singh, Cadman L Leggett, Prasad G Iyer, Kenneth K Wang
BACKGROUND AND AIMS: A small but significant proportion of patients with Barrett's esophagus (BE) have persistent dysplasia or intestinal metaplasia (IM) after treatment with radiofrequency ablation (RFA). Cryotherapy is a cold-based ablative modality that is increasingly being used in this setting. We aimed to better understand the efficacy of second-line cryotherapy in BE patients with persistent dysplasia or IM after RFA by conducting a systematic review and meta-analysis. METHODS: We performed a systematic literature search of PUBMED, EMBASE, and Web of Sciences through September 1, 2017...
February 21, 2018: Gastrointestinal Endoscopy
I Temblador-Barba, E M Delgado-Alonso, M Toribio-García, L Martínez-Campillo, I Molina-Leyva, M Martínez-Jiménez
CASE REPORT: Here we report a 19-year-old female patient who presented a vasoproliferative tumour. It caused complications, such as epiretinal membrane, macular oedema, vitreous haemorrhage, and exudative retinal detachment. The patient was treated with 3 injections of intravitreal bevacizumab, an intravitreal dexamethasone implant, tocilizumab, and double freeze-thaw cryotherapy. DISCUSSION: Therapeutic options are: observation, if it is small, if it is a peripheral lesion, and if there seems to be no threat to vision...
February 16, 2018: Archivos de la Sociedad Española de Oftalmología
M Vitenet, F Tubez, A Marreiro, G Polidori, R Taiar, F Legrand, F C Boyer
INTRODUCTION: Although fibromyalgia syndrome (SFM) affects 2-4 percent of adults, research has not identified a preferred therapeutic option for patients worldwide yet. Based on recent findings, it can be expected that whole body cryotherapy can improve health-reported quality of life by alleviating the symptoms of musculoskeletal pain and fatigue. OBJECTIVE: Our aim was to determine whether whole body cryotherapy only can result in improved perceived health and quality of life in fibromyalgia patients...
February 2018: Complementary Therapies in Medicine
Elena Quílez-Caballero, José Martel-Villagran, Ángel Luis Bueno-Horcajadas, Laura López-Brasal, María Jesús Díaz-Candamio
Osteoblastomatosis (OBLT), also referred to as multifocal osteoblastoma (OB), is an unusual and recently described entity consisting of multifocal tumors histologically consistent with osteoblastoma and osteoid osteoma (OO) but radiologically mimicking a vascular bone lesion. OBLT treatment is based on aggressive procedures, such as amputation, en bloc resection, and chemotherapy. Only one previously reported case was successfully treated following a multimodal approach consisting of curettage, cryotherapy, intravenous bisphosphonates, and radiofrequency ablation...
February 15, 2018: Skeletal Radiology
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