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https://www.readbyqxmd.com/read/28107730/systemic-atherosclerosis-and-voiding-symptom
#1
A Ozgur Yeniel, A Mete Ergenoglu, Reci Meseri, Anıl Ari, Ceren Sancar, Ismail Mete Itil
OBJECTIVE: To evaluate the effect of atherosclerosis on the storage and voiding symptoms of the bladder in women with overactive bladder (OAB). STUDY DESIGN: We retrospectively reviewed the charts of women with OAB who were evaluated between 2013 and 2015 in our urogynecology unit. Charts were assessed for history, examination findings, urinary diary, quality of life (QOL) questionnaires, urodynamic studies (UDSs), and four main risk factors for atherosclerosis: hypertension, diabetes mellitus, smoking, and hyperlipidemia...
January 9, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28104161/does-the-age-of-donor-kidneys-affect-nocturnal-polyuria-in-patients-with-successful-real-transplantation
#2
T Mitsui, K Morita, D Iwami, T Kitta, Y Kanno, K Moriya, M Takeda, N Shinohara
BACKGROUND: We investigated whether the age of donor kidneys influences the incidence of nocturnal polyuria in patients with successful renal transplantation (RTX). METHODS: Eighty-five patients (45 men and 40 women) undergoing RTX (median age, 47 years) were included in this study. Twenty-four-hour bladder diaries were kept for 3 days, and nocturnal polyuria was defined as a nocturnal polyuria index (nocturnal urine volume/24-hour urine volume) of >0.33. Risk factors for nocturnal polyuria were analyzed in patients with RTX by means of the Mann-Whitney U test, χ(2) test, and a logistic regression analysis...
January 2017: Transplantation Proceedings
https://www.readbyqxmd.com/read/28093307/the-impact-of-baseline-functional-bladder-capacity-on-short-term-neuromodulation-outcomes
#3
Kim A Killinger, Priyanka Gupta, Jason P Gilleran, Jamie Bartley, Michael Ehlert, Judith A Boura, Kenneth M Peters
OBJECTIVES: To evaluate the impact of functional bladder capacity (FBC) on clinical outcomes after a staged neuromodulation procedure. METHODS: Adults in our prospective neuromodulation database were evaluated. Data were collected from medical records, voiding diaries (FBC defined as average volume per void), Interstitial Cystitis Symptom/Problem Indices (ICSI-PI), Overactive Bladder Questionnaires (OAB-q), and Global Response Assessments over 3 months. Descriptive statistics, Pearson's Chi-square tests, Wilcoxon rank sum tests, logistic regression, repeated measures analyses and Spearman Correlation Coefficients were performed...
January 13, 2017: Urology
https://www.readbyqxmd.com/read/28089729/urinary-biomarkers-in-women-with-refractory-urgency-urinary-incontinence-randomized-to-sacral-neuromodulation-versus-onabotulinumtoxina-compared-to-controls
#4
Holly E Richter, Pamela Moalli, Cindy L Amundsen, Anna P Malykhina, Dennis Wallace, Rebecca Rogers, Deborah Myers, Maria Paraiso, Michael Albo, Haolin Shi, Tracy Nolen, Susie Meikle, R Ann Word
PURPOSE: To measure urinary biomarker levels in women with refractory urgency urinary incontinence (UUI) and controls at baseline and 6 months post treatment from sacral neuromodulation (SNM) or intradetrusor injection onabotulinumtoxinA and to assess association of baseline biomarkers to post treatment UUI episodes (UUIE) and overactive bladder (OAB) symptom bother outcomes. MATERIALS AND METHODS: First morning urines were collected from consented trial participants and age-matched women without UUI...
January 13, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28089606/parasacral-transcutaneous-electrical-neural-stimulation-ptens-once-a-week-for-the-treatment-of-overactive-bladder-in-children-a-randomized-controlled-trial
#5
Lidyanne Ilidia da Silva de Paula, Liliana Fajardo de Oliveira, Brysa Paiva Cruz, Dayana Maria de Oliveira, Laís Maini Miranda, Mauro de Moraes Ribeiro, Raphaela Ornellas Duque, André Avarese de Figueiredo, José de Bessa, José Murillo Bastos Netto
INTRODUCTION: Overactive bladder (OAB) is the most prevalent voiding disorder in childhood, and its main manifestation is urinary urgency. In general, urotherapy and anticholinergics are the first choices of treatment. Parasacral Transcutaneous Electrical Neural Stimulation (PTENS) was introduced as an alternative for the treatment of detrusor overactivity in children, but treatment protocols described to date require several sessions per week or long-lasting sessions, making it difficult for the child to adhere to the treatment...
December 21, 2016: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28074677/the-effective-tool-for-self-assessment-of-adherence-to-treatment-in-patients-with-benign-prostatic-obstruction-and-overactive-bladder-symptoms
#6
Kirill Kosilov, Sergey Loparev, Irina Kuzina, Olga Shakirova, Natalya Zhuravskaya, Alexandra Lobodenko
PURPOSE: Study of validity of the Medication Adherence Self-Report Inventory (MASRI) for use in clinical practice to treat patients with benign prostatic obstruction (BPO) accompanied with overactive bladder (OAB) symptoms. METHODS: During 12 weeks of the randomized study, 452 patients with BPO and OAB symptoms (mean age of 61.3 (12.7)) were studied for adherence to the treatment with Tamsulosin, Solifenacin and Trospium using the MASRI. External monitoring instruments included the Brief Medication Questionnaire (BMQ) and the visual remaining pill count...
January 11, 2017: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/28049246/efficacy-and-tolerability-of-solifenacin-5-mg-fixed-dose-in-korean-children-with-newly-diagnosed-idiopathic-overactive-bladder-a-multicenter-prospective-study
#7
Sang Don Lee, Jae Min Chung, Dong Il Kang, Dong Soo Ryu, Won Yeol Cho, Sungchan Park
We investigated the efficacy and tolerability of solifenacin 5 mg fixed dose in children with newly diagnosed idiopathic overactive bladder (OAB). A total of 34 children (male/female patients = 16/18) aged under 13 years (mean age: 7.2 ± 2.3; range: 5-12) who were newly diagnosed with OAB from January 2012 to September 2014 were prospectively evaluated with open-label protocol. All patients were treated with solifenacin 5 mg fixed dose once daily for at least 4 weeks. The efficacy and tolerability of solifenacin were evaluated 4, 8, and 12 weeks after the initiation of treatment...
February 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28043108/the-prevalence-of-nocturia-and-nocturnal-polyuria-can-new-cutoff-values-be-suggested-according-to-age-and-sex
#8
Ali Ersin Zumrutbas, Ali Ihsan Bozkurt, Okan Alkis, Cihan Toktas, Bulent Cetinel, Zafer Aybek
PURPOSE: The aims of this study were to assess the prevalence of nocturia and nocturnal polyuria (NP) and to define new cutoff values according to age and sex for both conditions. METHODS: Data from a population-based prevalence survey conducted among a random sample of 2,128 adults were analyzed in this study. Participants were requested to fill out a questionnaire including the International Continence Society (ICS) definitions of lower urinary tract symptoms and the International Consultation on Incontinence Questionnaire - Short Form...
December 2016: International Neurourology Journal
https://www.readbyqxmd.com/read/28040503/are-interferential-electrical-stimulation-and-diaphragmatic-breathing-exercises-beneficial-in-children-with-bladder-and-bowel-dysfunction
#9
Vesna D Zivkovic, Ivona Stankovic, Lidija Dimitrijevic, Mirjana Kocic, Hristina Colovic, Marina Vlajkovic, Andjelka Slavkovic, Milica Lazovic
OBJECTIVE: To evaluate the effects of interferential current (IC) stimulation and diaphragmatic breathing exercises (DBE) in children with bladder and bowel dysfunction. PATIENTS AND METHODS: Seventy-nine children with dysfunctional voiding and chronic constipation who were failures of primary care interventions were included in the prospective clinical study. All the children were checked for their medical history regarding LUTS and bowel habits. Physical examination including abdominal and anorectal digital examination were performed...
December 28, 2016: Urology
https://www.readbyqxmd.com/read/27987022/long-term-outcomes-of-intravesical-dimethyl-sulfoxide-heparin-hydrocortisone-therapy-for-interstitial-cystitis-bladder-pain-syndrome
#10
Yik N Lim, Peter Dwyer, Christine Murray, Debjyoti Karmakar, Anna Rosamilia, Elizabeth Thomas
INTRODUCTION AND HYPOTHESIS: For decades, intravesical dimethyl sulfoxide (DMSO) cocktail therapy has been used for the treatment of interstitial cystitis/bladder pain syndrome (IC/BPS), but little is known about its long-term efficacy. We aimed to assess the long-term efficacy of intravesical DMSO/heparin/hydrocortisone/bupivacaine therapy in patients with IC/BPS. METHODS: Patients with IC/BPS from our institutions who underwent this therapy with >2 years follow-up were surveyed with O'Leary-Sant interstitial cystitis symptom and problem index questionnaires before and after therapy...
December 16, 2016: International Urogynecology Journal
https://www.readbyqxmd.com/read/27914999/dual-therapy-for-refractory-overactive-bladder-in-children-a%C3%A2-prospective-open-label-study
#11
Fannie Morin, Anne-Sophie Blais, Geneviève Nadeau, Katherine Moore, Lucie Genois, Stéphane Bolduc
PURPOSE: Mirabegron (β3 adrenoreceptor agonist) is a new molecule with a mechanism of action distinct from antimuscarinics. Combination therapy with solifenacin was recently studied in an adult population. We evaluated the efficacy and safety of mirabegron as add-on therapy to treat urinary incontinence in children with idiopathic overactive bladder refractory/intolerant to antimuscarinics. MATERIALS AND METHODS: A prospective off-label study using add-on regimens of mirabegron was conducted in pediatric patients presenting with no symptom improvement while undergoing intensive behavioral and medical therapies and/or significant side effects while undergoing antimuscarinic dose escalation...
November 30, 2016: Journal of Urology
https://www.readbyqxmd.com/read/27887601/protocol-for-a-prospective-randomized-study-on-neurophysiological-assessment-of-lower-urinary-tract-function-in-a-healthy-cohort
#12
Stéphanie van der Lely, Martina Stefanovic, Melanie R Schmidhalter, Marta Pittavino, Reinhard Furrer, Martina D Liechti, Martin Schubert, Thomas M Kessler, Ulrich Mehnert
BACKGROUND: Lower urinary tract symptoms are highly prevalent and a large proportion of these symptoms are known to be associated with a dysfunction of the afferent pathways. Diagnostic tools for an objective and reproducible assessment of afferent nerve function of the lower urinary tract are missing. Previous studies showed first feasibility results of sensory evoked potential recordings following electrical stimulation of the lower urinary tract in healthy subjects and patients. Nevertheless, a refinement of the methodology is necessary...
November 25, 2016: BMC Urology
https://www.readbyqxmd.com/read/27867329/caffeine-as-a-probable-factor-for-increased-risk-of-oab-development-in-elderly-people
#13
Kirill V Kosilov, Sergay A Loparev, Marina A Ivanovskaya, Liliya V Kosilova
OBJECTIVE: This study was conducted to compare overactive bladder (OAB) prevalence among people greater than 60 years of age who intake various doses of caffeine, as well as those who abstain from caffeine. PATIENTS AND METHODS: A randomized observational study was carried out in Vladivostok Gerontological Hospital. A total of 1,098 retired people greater than 60 years of age (659 women and 439 men, average age 67.1 years) took part in the study. They were admitted to the in-patient department with the purpose of annual physical examination performed in accordance with the order of the Ministry of Public Health of the Russian Federation...
October 2016: Current Urology
https://www.readbyqxmd.com/read/27845219/efficacy-of-daily-low-dose-tadalafil-for-treating-overactive-bladder-results-of-a-randomized-double-blind-placebo-controlled-trial
#14
Hongde Chen, Feng Wang, Zhixian Yu, Yirong Zhang, Chaohui Liu, Shengjie Dai, Bicheng Chen, Jiaju Lv
OBJECTIVE: To evaluate the efficacy of daily low-dose tadalafil therapy for overactive bladder (OAB) in women. PATIENTS AND METHODS: A total of 96 women with idiopathic OAB from 3 medical centers in the south of Zhejiang Province of China were randomly assigned to treatment with daily low-dose tadalafil (5 mg, n = 48) or placebo (n = 48) for 3 months. The Indevus Urgency Severity Scale, overactive bladder symptom score (Homma et al, 2006), and a 3-day micturition diary with frequency, incontinence, and urgency episodes were recorded and compared before the treatment, every 2 weeks following the treatment, and 3 months after the treatment...
November 11, 2016: Urology
https://www.readbyqxmd.com/read/27813450/exploring-daily-blood-pressure-fluctuations-and-cardiovascular-risk-among-individuals-with-motor-complete-spinal-cord-injury-a-pilot-study
#15
Derry L Dance, Amit Chopra, Kent Campbell, David S Ditor, Magdy Hassouna, B Catharine Craven
BACKGROUND: Clinically silent autonomic dysfunction with bowel and bladder care, are postulated to contribute to cardiovascular disease after chronic spinal cord injury (SCI). OBJECTIVE: We describe the frequency and severity of dysreflexic episodes, termed transient blood pressure elevations (T-BPE) over 48 hours in adults with cervical or high-thoracic motor-complete SCI. SETTING: Tertiary SCI Rehabilitation Centre in Toronto, Canada. PARTICIPANTS: Individuals with chronic SCI, C1-T3 AIS A or B, >1 year post-injury, living in the community (n=19)...
November 4, 2016: Journal of Spinal Cord Medicine
https://www.readbyqxmd.com/read/27802001/correlation-between-overactive-bladder-symptom-score-and-neuropsychological-parameters-in-alzheimer-s-disease-patients-with-lower-urinary-tract-symptom
#16
Ha Bum Jung, Don Kyoung Choi, Seong Ho Lee, Sung Tae Cho, Hae Ri Na, Moon Ho Park
PURPOSE: To examine an association between the overactive bladder symptom score (OABSS) and neuropsychological parameters. Moreover, we investigate the factors that affect each item in the questionnaire. MATERIALS AND METHODS: A total of 376 patients (males: 184; females: 192) with probable Alzheimer's disease (AD) were recruited. Cognitive testing was conducted using the Mini Mental Status Examination (MMSE), Clinical Dementia Rating (CDR) scale, Global Deterioration Scale (GDS), and Barthel Activities of Daily Living (ADL)...
November 2, 2016: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/27794164/the-association-between-the-iciq-luts-and-the-iciq-bladder-diary-in-assessing-luts
#17
Haitham Abdelmoteleb, Mohamed I Kamel, Hashim Hashim
OBJECTIVES: The bladder diary (BD) provides a non-invasive method of investigating lower urinary tract symptoms (LUTS) while the International Consultation on Incontinence Questionnaires (ICIQ) symptom questionnaires, such as the ICIQ-MLUTS and ICIQ-FLUTS for males and females, respectively, provide a subjective assessment. The association between objective and subjective assessments has not been well established for the ICIQ. MATERIALS AND METHODS: Retrospective analysis of data collected from a urodynamics database was conducted...
October 29, 2016: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/27792298/potential-primary-endpoint-for-exploratory-clinical-trial-in-patients-with-overactive-bladder-a-systematic-literature-review
#18
Shingo Iino, Masayuki Kaneko, Mamoru Narukawa
OBJECTIVES: To identify a potential primary endpoint in an early-phase exploratory trial among key overactive bladder (OAB) symptoms. METHODS: Placebo-controlled double-blinding trials in patients with OAB were extracted for systematic literature review. The correlation between key OAB symptoms recorded in bladder diaries and coefficient of variation (CV) in each study were assessed. RESULTS: Forty-one controlled trials were extracted for the present review...
October 28, 2016: Lower Urinary Tract Symptoms
https://www.readbyqxmd.com/read/27753248/nocturia-is-often-inadequately-assessed-diagnosed-and-treated-by-physicians-results-of-an-observational-real-life-practice-database-containing-8659-european-and-us-american-patients
#19
Matthias Oelke, Peter Anderson, Robert Wood, Tove Holm-Larsen
AIMS: The aim of this study was to investigate the quality and timing of the diagnosis and treatment of nocturia in real-life practice in European and US-American patients to obtain better insights into the management of nocturia in different Western healthcare systems. METHODS: Data were drawn from the "LUTS Disease Specific Programme," a real-life survey of physicians and patients in France, Germany, Spain, UK and the USA. Physicians completed a patient record form for lower urinary tract symptoms (LUTS) patients...
November 2016: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/27752750/methodology-for-a-trial-of-brain-centered-versus-anticholinergic-therapy-in-women-with-urgency-urinary-incontinence
#20
Yuko M Komesu, Rebecca G Rogers, Robert E Sapien, Ronald M Schrader, Timothy Simmerman-Sierra, Andrew R Mayer, Loren H Ketai
INTRODUCTION AND HYPOTHESIS: We describe the rationale and methodology for a study comparing mind-body treatment and pharmacotherapy in women with urgency urinary incontinence (UUI). To explore brain associations in UUI, a subset of patients will also undergo functional magnetic resonance imaging (fMRI). We hypothesize that hypnotherapy, a mind-body intervention, will be at least as effective as pharmacotherapy in treating UUI. We also hypothesize that fMRI findings will change following treatment, with changes potentially differing between groups...
October 17, 2016: International Urogynecology Journal
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