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https://www.readbyqxmd.com/read/29058218/ontology-based-vaccine-adverse-event-representation-and-analysis
#1
Jiangan Xie, Yongqun He
Vaccine is the one of the greatest inventions of modern medicine that has contributed most to the relief of human misery and the exciting increase in life expectancy. In 1796, an English country physician, Edward Jenner, discovered that inoculating mankind with cowpox can protect them from smallpox (Riedel S, Edward Jenner and the history of smallpox and vaccination. Proceedings (Baylor University. Medical Center) 18(1):21, 2005). Based on the vaccination worldwide, we finally succeeded in the eradication of smallpox in 1977 (Henderson, Vaccine 29:D7-D9, 2011)...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/29056387/partitioning-multi-source-uncertainties-in-simulating-nitrogen-loading-in-stream-water-using-a-coherent-stochastic-framework-application-to-a-rice-agricultural-watershed-in-subtropical-china
#2
Qiumei Ma, Lihua Xiong, Yong Li, Siyue Li, Chong-Yu Xu
Uncertainty is recognized as a critical consideration for accurately predicting stream water nitrogen (N) loading, but identifying the relative contribution of individual uncertainty sources within the total uncertainty remains unclear. In this study, a powerful method, referred to as the Bayesian inference combined with analysis of variance (BayeANOVA) was adopted to detect the timing and magnitude of multiple uncertainty sources and their relative contributions to total uncertainty in simulating daily loadings of three stream water N species (ammonium-N: NH4(+)-N, nitrate-N: NO3(-)-N and total N: TN) in a rice agricultural watershed (the Tuojia watershed) as influenced by non-point source N pollution...
October 19, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29056100/international-adoption-of-children-surviving-the-haitian-earthquake
#3
Julie Pascal, Marion Décombas-Marion, Véronique Poirier, Alexandre Lautrette, Emilie Rigal, Julie Sciauvaud, Bruno Pereira, André Labbe, Olivier Lesens
OBJECTIVE: To evaluate resilience and frequency of behavioral symptoms in Haitian children internationally adopted before and after the earthquake of January 12, 2010. METHODS: We conducted a retrospective quantitative study in 40 Haitian children. Families were also asked to participate in a qualitative study (individual interview at 18-24 months after the earthquake) and to complete State-Trait Anxiety Inventory (STAI) and STAI for children (STAI-C) questionnaires...
October 23, 2017: Disaster Medicine and Public Health Preparedness
https://www.readbyqxmd.com/read/29055899/are-quality-improvement-collaboratives-effective-a-systematic-review
#4
REVIEW
Susan Wells, Orly Tamir, Jonathon Gray, Dhevaksha Naidoo, Mark Bekhit, Don Goldmann
BACKGROUND: Quality improvement collaboratives (QIC) have proliferated internationally, but there is little empirical evidence for their effectiveness. METHOD: We searched Medline, Embase, CINAHL, PsycINFO and the Cochrane Library databases from January 1995 to December 2014. Studies were included if they met the criteria for a QIC intervention and the Cochrane Effective Practice and Organisation of Care (EPOC) minimum study design characteristics for inclusion in a review...
October 21, 2017: BMJ Quality & Safety
https://www.readbyqxmd.com/read/29055177/pesticide-management-approach-towards-protecting-the-safety-and-health-of-farmers-in-southeast-asia
#5
REVIEW
Norsyazwani Mohammad, Emilia Zainal Abidin, Vivien How, Sarva Mangala Praveena, Zailina Hashim
BACKGROUND: It is estimated that pesticide production and use have increased continuously in the countries of Southeast Asia in recent years. Within the context of protecting the safety and health of workers in the agricultural sector, there is an existing gap in the implementation of the pesticide management framework because safety and health effects arising from occupational exposures continue to be reported. OBJECTIVE: This study aims to provide narrative similarities, differences and weaknesses of the existing pesticide management system in Southeast Asian countries (Brunei, Cambodia, Indonesia, Laos, Malaysia, Myanmar, Philippines, Singapore, Thailand and Vietnam) within the context of occupational safety and health...
October 21, 2017: Reviews on Environmental Health
https://www.readbyqxmd.com/read/29054815/whole-brain-radiotherapy-or-autologous-stem-cell-transplantation-as-consolidation-strategies-after-high-dose-methotrexate-based-chemoimmunotherapy-in-patients-with-primary-cns-lymphoma-results-of-the-second-randomisation-of-the-international-extranodal-lymphoma
#6
Andrés J M Ferreri, Kate Cwynarski, Elisa Pulczynski, Christopher P Fox, Elisabeth Schorb, Paul La Rosée, Mascha Binder, Alberto Fabbri, Valter Torri, Eleonora Minacapelli, Monica Falautano, Fiorella Ilariucci, Achille Ambrosetti, Alexander Roth, Claire Hemmaway, Peter Johnson, Kim M Linton, Tobias Pukrop, Jette Sønderskov Gørløv, Monica Balzarotti, Georg Hess, Ulrich Keller, Stephan Stilgenbauer, Jens Panse, Alessandra Tucci, Lorella Orsucci, Francesco Pisani, Alessandro Levis, Stefan W Krause, Hans J Schmoll, Bernd Hertenstein, Mathias Rummel, Jeffery Smith, Michael Pfreundschuh, Giuseppina Cabras, Francesco Angrilli, Maurilio Ponzoni, Martina Deckert, Letterio S Politi, Jürgen Finke, Michele Reni, Franco Cavalli, Emanuele Zucca, Gerald Illerhaus
BACKGROUND: The International Extranodal Lymphoma Study Group-32 (IELSG32) trial is an international randomised phase 2 study that addresses two key clinical questions in the treatment of patients with newly diagnosed primary CNS lymphoma. Results of the first randomisation have demonstrated that methotrexate, cytarabine, thiotepa, and rituximab (called the MATRix regimen) is the induction combination associated with significantly better outcome compared with the other induction combinations tested...
October 17, 2017: Lancet Haematology
https://www.readbyqxmd.com/read/29050908/hand-hygiene-attitudes-and-practices-of-nurses-a-comparison-between-2007-and-2015
#7
Liz M Kingston, Barbara L Slevin, Nuala H O'Connell, Colum P Dunne
BACKGROUND: Hand hygiene reduces health care-associated infections significantly. However, international evidence suggests that practices are suboptimal. The objective of this study was to compare and contrast hand hygiene attitudes and practices and alcohol-based handrub (ABHR) use among nurses between 2007 and 2015. METHODS: In 2007, a random sample of nurses in a large teaching hospital was invited to complete a postal survey using a validated questionnaire. In 2015, the study was replicated among all nurses employed in a university hospital group, including the setting of the original study...
October 16, 2017: American Journal of Infection Control
https://www.readbyqxmd.com/read/29048806/-determination-of-hexabromocyclododecanes-in-ambient-air-by-high-performance-liquid-chromatography-electrospray-ionization-mass-spectrometry
#8
Yan Li, Longxing Wang, Xiuhua Zhu, Yuan Gao, Jiping Chen
A high performance liquid chromatography-electrospray ionization-mass spectrometry (HPLC-ESI-MS) method was developed for the determination of hexabromocyclododecanes (HBCDs) in ambient air samples. The samples were extracted by Soxhlet extractor with hexane, then purified on the composite gel column. At first, the interfering substances were rinsed with 50 mL hexane and 100 mL hexane-dichloromethane (9:1, v/v), then 180 mL hexane -dichloromethane (4:1, v/v) was used to elute the targets. The compounds were separated by gradient elution with acetonitrile-methanol-water as mobile phases on a UF-ODS column (150 mm×2...
October 8, 2017: Se Pu, Chinese Journal of Chromatography
https://www.readbyqxmd.com/read/29042387/nature-based-care-opportunities-and-barriers-in-oncology-contexts-a-modified-international-e-delphi-survey
#9
Sarah Blaschke, Clare C O'Callaghan, Penelope Schofield
OBJECTIVE: To develop recommendations regarding opportunities and barriers for nature-based care in oncology contexts using a structured knowledge generation process involving relevant healthcare and design experts. DESIGN: Four-round modified electronic Delphi study. Oncology patients' nature-based recommendations, uncovered in preceding qualitative investigation, were included in the first round for the expert participants' consideration. Key items (opportunities and barriers) were developed using data aggregation and synthesis, followed by item prioritisation and 10-point Likert scale ranking (1=not important, 10=very important)...
October 16, 2017: BMJ Open
https://www.readbyqxmd.com/read/29042145/electronic-clinical-evaluation-exercise-e-cex-a-new-patient-centered-ehr-use-tool
#10
Maria Alcocer Alkureishi, Wei Wei Lee, Maureen Lyons, Kristen Wroblewski, Jeanne M Farnan, Vineet M Arora
INTRODUCTION: Electronic Health Record (EHR) use can enhance or weaken patient-provider communication. Despite EHR adoption, no validated tool exists to assess EHR communication skills. We aimed to develop and validate such a tool. METHODS: Electronic-Clinical Evaluation Exercise (e-CEX) is a 10-item-tool based on systematic literature review and pilot-testing. Second-year (MS2s) students participated in an EHR-use lecture and structured Clinical Examination (OSCE)...
October 10, 2017: Patient Education and Counseling
https://www.readbyqxmd.com/read/29040184/proceedings-from-the-1st-international-conference-current-concepts-and-controversies-in-gynecologic-and-urologic-oncology
#11
Olga Matylevich, Sergey Mavrichev, Andrei Pletnev, Alesya Evmenenko, Aleksey Shevchuk, Valentina Suslova, Sergey Taranenko, Elena Dolomanova, Dmitry Rovsky, Anna Portyanko, Jubilee Brown, Robert Wendel Naumann, Kathleen Schmeler, Anna Plotkin, Sophia Michaelson, Mary Eiken, Edward Trimble, Thomas Randall
The N.N. Alexandrov National Cancer Center of Belarus organized a collaborative international conference entitled 'Current Concepts and Controversies in Gynecologic and Urologic Oncology' with the International Gynecologic Cancer Society and the United States National Cancer Institute. International, regional, and national experts presented recent developments and local conditions in the treatment of gynecologic cancers. Findings were reviewed with the intent of optimizing the management of women with gynecologic cancers across the Commonwealth of Independent States region...
October 17, 2017: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/29039366/a-socio-technical-analysis-of-patient-accessible-electronic-health-records
#12
Maria Hägglund, Isabella Scandurra
In Sweden, and internationally, there is a movement towards increased transparency in healthcare including giving patients online access to their electronic health records (EHR). The purpose of this paper is to analyze the Swedish patient accessible EHR (PAEHR) service using a socio-technical framework, to increase the understanding of factors that influence the design, implementation, adoption and use of the service. Using the Sitting and Singh socio-technical framework as a basis for analyzing the Swedish PAEHR system and its context indicated that there are many stakeholders engaged in these types of services, with different driving forces and incentives that may influence the adoption and usefulness of PAEHR services...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/29037339/-beyond-cognitive-impairment-neuropsychiatric-symptoms-in-neurodegenerative-dementias
#13
Luisa Fernanda Ahunca Velásquez
As life expectancy increases, the number of people diagnosed with neurodegenerative dementia also increases. Although cognitive impairment is central in dementia, neuropsychiatric symptoms (NPS) are very important because they increase both direct and indirect costs by generating greater morbidity, caregiver distress, use of medication and institutionalisation. Furthermore, it is important to understand the nature of NPS, since they can vary across the different types of dementia and may provide useful clinical information regarding the aetiology of cognitive impairment...
October 2017: Revista Colombiana de Psiquiatría
https://www.readbyqxmd.com/read/29037334/an-international-curriculum-for-neuropsychiatry-and-behavioural-neurology
#14
Perminder Sachdev, Adith Mohan
With major advances in neuroscience in the last three decades, there is an emphasis on understanding disturbances in thought, behaviour and emotion in terms of their neuroscientific underpinnings. While psychiatry and neurology, both of which deal with brain diseases, have a historical standing as distinct disciplines, there has been an increasing need to have a combined neuropsychiatric approach to deal with many conditions and disorders. Additionally, there is a body of disorders and conditions that warrants the skills sets and knowledge bases of both disciplines...
October 2017: Revista Colombiana de Psiquiatría
https://www.readbyqxmd.com/read/29036837/simvastatin-as-a-potential-disease-modifying-therapy-for-patients-with-parkinson-s-disease-rationale-for%C3%A2-clinical-trial-and-current-progress
#15
Camille B Carroll, Richard K H Wyse
Many now believe the holy grail for the next stage of therapeutic advance surrounds the development of disease-modifying approaches aimed at intercepting the year-on-year neurodegenerative decline experienced by most patients with Parkinson's disease (PD). Based on recommendations of an international committee of experts who are currently bringing multiple, potentially disease-modifying, PD therapeutics into long-term neuroprotective PD trials, a clinical trial involving 198 patients is underway to determine whether Simvastatin provides protection against chronic neurodegeneration...
October 13, 2017: Journal of Parkinson's Disease
https://www.readbyqxmd.com/read/29036693/icg-a-wiki-driven-knowledgebase-of-internal-control-genes-for-rt-qpcr-normalization
#16
Jian Sang, Zhennan Wang, Man Li, Jiabao Cao, Guangyi Niu, Lin Xia, Dong Zou, Fan Wang, Xingjian Xu, Xiaojiao Han, Jinqi Fan, Ye Yang, Wanzhu Zuo, Yang Zhang, Wenming Zhao, Yiming Bao, Jingfa Xiao, Songnian Hu, Lili Hao, Zhang Zhang
Real-time quantitative PCR (RT-qPCR) has become a widely used method for accurate expression profiling of targeted mRNA and ncRNA. Selection of appropriate internal control genes for RT-qPCR normalization is an elementary prerequisite for reliable expression measurement. Here, we present ICG (http://icg.big.ac.cn), a wiki-driven knowledgebase for community curation of experimentally validated internal control genes as well as their associated experimental conditions. Unlike extant related databases that focus on qPCR primers in model organisms (mainly human and mouse), ICG features harnessing collective intelligence in community integration of internal control genes for a variety of species...
October 3, 2017: Nucleic Acids Research
https://www.readbyqxmd.com/read/29034674/-has-budget-impact-analysis-guidelines-a-new-decision-making-tool
#17
Salah Ghabri, Anne-Isabelle Poullié, Erwan Autin, Jean-Michel Josselin
INTRODUCTION: Budget impact analysis (BIA) provides short and medium-term estimates on changes in budgets and resources resulting from the adoption of new health interventions. OBJECTIVE: The objective of this article is to present the main messages of the newly developed French National Authority for Health (HAS) guidelines on budget impact analysis : issues, recommendations and perspectives. METHODS: The HAS guidelines development process was based on data derived from a literature review on BIA (search dates : January 2000 to June 2016), an HAS retrospective investigation, a public consultation, international expert advice, and approval from the HAS Board and the Economic and Public Health Evaluation Committee...
October 2, 2017: Santé Publique: Revue Multidisciplinaire Pour la Recherche et L'action
https://www.readbyqxmd.com/read/29033954/setaria-comes-of-age-meeting-report-on-the-second-international-setaria-genetics-conference
#18
Chuanmei Zhu, Jiani Yang, Christine Shyu
Setaria viridis is an emerging model for cereal and bioenergy grasses because of its short stature, rapid life cycle and expanding genetic and genomic toolkits. Its close phylogenetic relationship with economically important crops such as maize and sorghum positions Setaria as an ideal model system for accelerating discovery and characterization of crop genes that control agronomically important traits. The Second International Setaria Genetics Conference was held on March 6-8, 2017 at the Donald Danforth Plant Science Center, St...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/29030040/sedimentation-assisted-preparation-of-ground-particles-of-silica-monolith-and-their-c18-modification-resulting-in-a-chromatographic-phase-of-improved-separation-efficiency
#19
Ashraf Ali, Faiz Ali, Won Jo Cheong
The sedimentation procedure has been adopted in production of ground silica monolith particles to improve chromatographic separation efficiency of the resultant phase. First, silica monolith particles have been successfully prepared in a large scale by a sol-gel process followed by grinding. The particles after calcination were separated by sedimentation into three zones using an Imhoff sedimentation cone. The particles of the bottom zone were derivatized with a C18 ligand and end-capped. The sedimentation process was found to not only eliminate troublesome minute particles but also narrow down the particle size distribution...
October 6, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/29029689/implementation-of-a-cloud-based-electronic-medical-record-exchange-system-in-compliance-with-the-integrating-healthcare-enterprise-s-cross-enterprise-document-sharing-integration-profile
#20
Chien Hua Wu, Ruey Kei Chiu, Hong Mo Yeh, Da Wei Wang
In 2011, the Ministry of Health and Welfare of Taiwan established the National Electronic Medical Record Exchange Center (EEC) to permit the sharing of medical resources among hospitals. This system can presently exchange electronic medical records (EMRs) among hospitals, in the form of medical imaging reports, laboratory test reports, discharge summaries, outpatient records, and outpatient medication records. Hospitals can send or retrieve EMRs over the virtual private network by connecting to the EEC through a gateway...
November 2017: International Journal of Medical Informatics
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