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https://www.readbyqxmd.com/read/29468281/-current-guideline-oriented-follow-up-of-small-renal-masses-applied-risk-scores-and-future-outlook
#1
REVIEW
V Stühler, S Kruck, T Todenhöfer, A Stenzl, J Bedke
After surgical resection of renal cell carcinoma by laparoscopic or open partial or complete nephrectomy, medical aftercare based on the current guidelines should be provided. This seems desirable, especially because one third of patients after initial curative tumor resection develop recurrence over time. In this article, the current recommendations for follow-up will be systematically presented based on the accepted German S3 guideline and the European Association of Urology (EAU) guideline. Another point of this article will be the presentation of the currently applied risk scores to predict prognosis with a focus on molecular markers...
February 21, 2018: Der Urologe. Ausg. A
https://www.readbyqxmd.com/read/29445855/-treatment-strategy-for-early-stage-rectal-cancer-t1-carcinoma
#2
REVIEW
G Liebig-Hörl, C Puchner, M Gerken, M Klinkhammer-Schalke, A Fürst
BACKROUND: A common consensus for the definition for early rectal cancer does not exist. This item is used in cases of histological findings including pTis, pT1 or pT2 tumors. The term early rectal cancer is not mentioned in the German S3 guidelines on colorectal cancer. The pTis tumors are located at the mucosa level of the intestinal wall and they have nearly no tendency to develop metastases but pT2 tumors have a high risk of local metastases; therefore, the term early rectal cancer is not adequate for pT2 tumors...
February 14, 2018: Der Chirurg; Zeitschrift Für Alle Gebiete der Operativen Medizen
https://www.readbyqxmd.com/read/29427005/multicenter-evaluation-of-guideline-adherence-for-pelvic-lymph-node-dissection-in-patients-undergoing-open-retropubic-vs-laparoscopic-or-robot-assisted-radical-prostatectomy-according-to-the-recent-german-s3-guideline-on-prostate-cancer
#3
Angelika Borkowetz, Johannes Bruendl, Martin Drerup, Jonas Herrmann, Hendrik Isbarn, Burkhard Beyer
PURPOSE: Pelvic lymph node dissection (PLND) is recommended for patients with prostate cancer (PCa) and significant risk for nodal metastases. This study aimed to assess guideline adherence regarding PLND according to the German S3 guideline as example for a national but highly used guideline on prostate cancer and to compare the rate of complications different approaches for radical prostatectomy (RP). METHODS: Patients undergoing open (RRP), laparoscopic (LARP) or robot-assisted (RARP) RP in six centers in Germany and Austria were included...
February 9, 2018: World Journal of Urology
https://www.readbyqxmd.com/read/29417163/-profit-center-analysis-of-esophagectomy-economical-analysis-of-transthoracic-esophagectomy-depending-on-postoperative-complications
#4
C T Baltin, M Bludau, F Kron, T Zander, M Hallek, A H Hölscher, W Schröder
Due to increasing medical costs and yet limited financial resources, medical treatment and economic analyses can no longer be separated; therefore, direct costing and cost unit accounting become more and more relevant as controlling tools in hospital management. Transthoracic esophagectomy is an integral part of the current treatment concept in patients with esophageal carcinoma. The question of the present study was whether the present diagnosis-related groups (DRG) system is a cost-effective tool to represent transthoracic esophagectomy...
February 7, 2018: Der Chirurg; Zeitschrift Für Alle Gebiete der Operativen Medizen
https://www.readbyqxmd.com/read/29404648/-psychotherapy-of-depressive-disorders-evidence-in-chronic-depression-and-comorbidities
#5
REVIEW
M Härter, A Jansen, M Berger, H Baumeister, T Bschor, T Harfst, M Hautzinger, L Kriston, C Kühner, H Schauenburg, S G Schorr, F Schneider, R Meister
BACKGROUND: Psychotherapy has been shown to be an effective treatment option for depressive disorders; however, its effectiveness varies depending on patient and therapist characteristics and the individual form of the depressive disorder. OBJECTIVES: The aim of this article is to present the current evidence for psychotherapeutic antidepressive treatments for patients with chronic and treatment-resistant depression as well as for patients with mental and somatic comorbidities...
February 5, 2018: Der Nervenarzt
https://www.readbyqxmd.com/read/29392342/-surgical-strategy-for-early-stage-carcinoma-of-the-esophagus
#6
REVIEW
N Niclauss, M Chevallay, J L Frossard, S P Mönig
Early stage carcinomas of the esophagus are histologically differentiated into adenocarcinomas and squamous cell carcinomas and subdivided into mucosal (m1-3) and submucosal (sm1-3) carcinomas depending on the infiltration depth. While the prevalence of lymph node metastases in mucosal carcinomas is very low, the probability of lymph node metastases increases from submucosal infiltration with increasing depth. According to the current German S3 guidelines endoscopic resection is the recommended treatment strategy for mucosal adenocarcinoma without histological risk factors (lymphatic invasion [L1], venous invasion [V1], poorly differentiated [>G2], microscopic residual disease [R1] at the deep resection margin)...
February 1, 2018: Der Chirurg; Zeitschrift Für Alle Gebiete der Operativen Medizen
https://www.readbyqxmd.com/read/29383414/-psychotherapy-of-depressive-disorders-procedures-evidence-and-perspectives
#7
REVIEW
R Meister, A Jansen, M Berger, H Baumeister, T Bschor, T Harfst, M Hautzinger, L Kriston, C Kühner, H Schauenburg, S G Schorr, F Schneider, M Härter
BACKGROUND: Depressive disorders are associated with a high burden of suffering and significantly reduce the well-being and the self-esteem of affected patients. Psychotherapy is one of the main treatment options for depressive disorders. OBJECTIVE: The aim of this article is to present the current evidence for antidepressive psychotherapeutic treatments. MATERIAL AND METHODS: During the revision of the German S3- and National Disease Management Guideline (NDMG) on unipolar depression in 2015, a comprehensive and systematic evidence search was conducted...
January 30, 2018: Der Nervenarzt
https://www.readbyqxmd.com/read/29359282/-health-care-organization-the-new-german-s3-guideline-on-alcohol-related-disorders-and-its-relevance-for-health-care
#8
Arthur Günthner, Volker Weissinger, Heribert Fleischmann, Clemens Veltrup, Bettina Jäpel, Gerhard Längle, Klaus Amann, Eva Hoch, Karl Mann
BACKGROUND: Alcohol dependence is one of the most serious diseases of addiction in Germany. The new S3-guideline "Screening, Diagnostics and Treatment of Alcohol-Related Disorders" has been presented in 2015 and summarizes the present state of knowledge pertaining to the diagnosis and treatment of alcohol abuse and alcohol dependence. METHODS: This guideline was developed over four years within the framework of the Association of the Scientific Medical Societies in Germany (AWMF)...
January 22, 2018: Die Rehabilitation
https://www.readbyqxmd.com/read/29341041/screening-interval-recommendations-following-a-normal%C3%A2-colonoscopy-in-individuals-with-a-familial-risk-of%C3%A2-colorectal-cancer
#9
Jasper Plath, Andrea Siebenhofer, Corina Guethlin, Irina Blumenstein
BACKGROUND:  In view of the increased risk of developing colorectal cancer (CRC) in individuals with affected first-degree relatives (FDRs), the German evidence-based S3 guideline recommends having the first screening colonoscopy early and then, following a normal examination, repeating it at least every 10 years. The aim of this analysis was to explore colonoscopy interval recommendations in clinical practice among individuals aged < 55 years with a familial risk of CRC. METHODS:  We analyzed data from the FRIDA...
January 16, 2018: Zeitschrift Für Gastroenterologie
https://www.readbyqxmd.com/read/29341032/-epidemiology-diagnosis-and-treatment-of-adult-patients-with-nosocomial-pneumonia-update-2017-s3-guideline-of-the-german-society-for-anaesthesiology-and-intensive-care-medicine-the-german-society-for-infectious-diseases-the-german-society-for-hygiene-and-microbiology
#10
K Dalhoff, M Abele-Horn, S Andreas, M Deja, S Ewig, P Gastmeier, S Gatermann, H Gerlach, B Grabein, C P Heußel, G Höffken, M Kolditz, E Kramme, H Kühl, C Lange, K Mayer, I Nachtigall, M Panning, M Pletz, P-M Rath, G Rohde, S Rosseau, B Schaaf, D Schreiter, H Schütte, H Seifert, C Spies, T Welte
Nosocomial pneumonia (HAP) is a frequent complication of hospital care. Most data are available on ventilator-associated pneumonia. However, infections on general wards are increasing. A central issue are infections with multidrug resistant (MDR) pathogens which are difficult to treat in the empirical setting potentially leading to inappropriate use of antimicrobial therapy.This guideline update was compiled by an interdisciplinary group on the basis of a systematic literature review. Recommendations are made according to GRADE giving guidance for the diagnosis and treatment of HAP on the basis of quality of evidence and benefit/risk ratio...
January 2018: Pneumologie
https://www.readbyqxmd.com/read/29329578/guideline-based-quality-indicators-a-systematic-comparison-of-german-and-international-clinical-practice-guidelines-protocol-for-a-systematic-review
#11
Monika Becker, Jessica Breuing, Monika Nothacker, Stefanie Deckert, Mirco Steudtner, Jochen Schmitt, Edmund Neugebauer, Dawid Pieper
BACKGROUND: Quality indicators (QIs) are used in assessing the quality of healthcare. Evidence-based clinical practice guidelines (CPGs) are relevant sources for generating QIs. In this context, QIs are important tools to assess the implementation of guideline recommendations. However, the methodological approaches to guideline-based QI development vary considerably. In Germany, the guideline classification scheme of the AWMF (German Association of the Scientific Medical Societies) differentiates between S1-, S2k-, S2e-, and S3-CPGs depending on the methodological approach...
January 12, 2018: Systematic Reviews
https://www.readbyqxmd.com/read/29241445/shifting-cancer-care-towards-multidisciplinarity-the-cancer-center-certification-program-of-the-german-cancer-society
#12
Christoph Kowalski, Ullrich Graeven, Christof von Kalle, Hauke Lang, Matthias W Beckmann, Jens-Uwe Blohmer, Martin Burchardt, Michael Ehrenfeld, Jan Fichtner, Stephan Grabbe, Hans Hoffmann, Heinrich Iro, Stefan Post, Anton Scharl, Uwe Schlegel, Thomas Seufferlein, Walter Stummer, Dieter Ukena, Julia Ferencz, Simone Wesselmann
BACKGROUND: Over the last decades numerous initiatives have been set up that aim at translating the best available medical knowledge and treatment into clinical practice. The inherent complexity of the programs and discrepancies in the terminology used make it difficult to appreciate each of them distinctly and compare their specific strengths and weaknesses. To allow comparison and stimulate dialogue between different programs, we in this paper provide an overview of the German Cancer Society certification program for multidisciplinary cancer centers that was established in 2003...
December 14, 2017: BMC Cancer
https://www.readbyqxmd.com/read/29238847/which-pre-hospital-triage-parameters-indicate-a-need-for-immediate-evaluation-and-treatment-of-severely-injured-patients-in-the-resuscitation-area
#13
K O Jensen, R Heyard, D Schmitt, L Mica, C Ossendorf, H P Simmen, G A Wanner, C M L Werner, L Held, K Sprengel
PURPOSE: To find ways to reduce the rate of over-triage without drastically increasing the rate of under-triage, we applied a current guideline and identified relevant pre-hospital triage predictors that indicate the need for immediate evaluation and treatment of severely injured patients in the resuscitation area. METHODS: Data for adult trauma patients admitted to our level-1 trauma centre in a one year period were collected. Outpatients were excluded. Correct triage for trauma team activation was identified for patients with an ISS or NISS ≥ 16 or the need for ICU treatment due to trauma sequelae...
December 13, 2017: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
https://www.readbyqxmd.com/read/29213210/german-s3%C3%A2-guideline-nonrestorative-sleep-sleep-disorders-chapter-sleep-related-breathing-disorders-in-adults-short-version-german-sleep-society-deutsche-gesellschaft-f%C3%A3-r-schlafforschung-und-schlafmedizin-dgsm
#14
REVIEW
Geert Mayer, Michael Arzt, Bert Braumann, Joachim H Ficker, Ingo Fietze, Helmut Frohnhofen, Wolfgang Galetke, Joachim T Maurer, Maritta Orth, Thomas Penzel, Hans Pistner, Winfried Randerath, Martin Rösslein, Helmut Sitter, Boris A Stuck
No abstract text is available yet for this article.
2017: Somnologie: Schlafforschung und Schlafmedizin, Somnology: Sleep Research and Sleep Medicine
https://www.readbyqxmd.com/read/29159490/-prewarming-according-to-the-awmf-s3-guidelines-on-preventing-inadvertant-perioperative-hypothermia-2014-retrospective-analysis-of-7786-patients
#15
R Grote, A J Wetz, A Bräuer, M Menzel
BACKGROUND: Inadvertent perioperative hypothermia, which is defined as a core body temperature of less than 36.0 °C, can have serious consequences in surgery patients. These include cardiac complications, increased blood loss, wound infections and postoperative shivering; therefore, the scientific evidence that inadvertent perioperative hypothermia should be avoided is undisputed and several national guidelines have been published summarizing the scientific evidence and recommending specific procedures...
November 20, 2017: Der Anaesthesist
https://www.readbyqxmd.com/read/29098307/-therapeutic-approach-in-oligometastatic-gastric-and-esophageal-cancer
#16
REVIEW
T Schmidt, S P Mönig
The therapeutic approach to patients with oligometastatic gastric cancer and esophageal cancer is currently undergoing a shift towards a more aggressive therapy including surgical resection. In the current German S3 guidelines surgical treatment of metastatic disease is not recommended; however, nowadays interdisciplinary tumor boards have to evaluate such patients increasingly more often. On an individual basis a radical surgical resection of the primary tumor and the metastases is considered and performed in patients who respond well to multimodal chemotherapy concepts...
November 2, 2017: Der Chirurg; Zeitschrift Für Alle Gebiete der Operativen Medizen
https://www.readbyqxmd.com/read/29094875/heart-failure-with-preserved-ejection-fraction-diagnosis-and-management
#17
REVIEW
John D Gazewood, Patrick L Turner
Heart failure with preserved ejection fraction, also referred to as diastolic heart failure, causes almost one-half of the 5 million cases of heart failure in the United States. It is more common among older patients and women, and results from abnormalities of active ventricular relaxation and passive ventricular compliance, leading to a decline in stroke volume and cardiac output. Heart failure with preserved ejection fraction should be suspected in patients with typical symptoms (e.g., fatigue, weakness, dyspnea, orthopnea, paroxysmal nocturnal dyspnea, edema) and signs (S3 heart sound, displaced apical pulse, and jugular venous distension) of chronic heart failure...
November 1, 2017: American Family Physician
https://www.readbyqxmd.com/read/29078245/-antiembolic-stockings-great-effects-in-edoxaban-approval-studies
#18
Knut Kroeger, Peter Kujath
In this age of evidence-based medicine, the use of medical thrombosis prophylaxis stockings (AES) as a physical strategy for the prevention of lower limb venous thrombosis has been questioned. The current German S3 guidelines even state that their non-application is, in the vast majority of cases, explicitly covered by the recommendations of this guideline. Low molecular weight heparins (NMH) and direct oral anticoagulants (DOAK) have received approval for thrombosis prophylaxis in elective knee and hip joint replacement, but the use of AES is absent from these approval studies...
October 2017: Zentralblatt Für Chirurgie
https://www.readbyqxmd.com/read/29038912/-erratum-to-the-2016-update-of-the-s3-guideline-for-malignant-tumours-of-the-ovary-role-of-pathology-in-diagnosis-therapy-and-clinical-management-of-epithelial-tumours
#19
https://www.readbyqxmd.com/read/29017230/-guidelines-in-practice-the-new-s3-guideline-sleeping-disorders-sleep-related-abnormal-breathing
#20
Martin Gerlach, Bernd Sanner
Sleep related breathing disorders include central sleep apnea (CSA), obstructive sleep apnea (OSA), sleep-related hypoventilation, and sleep-related hypoxia. These disorders are frequent and growing in clinical relevance. The related chapter of the S3 guideline "Non-restorative sleep/Sleep disorders", published by the German Sleep Society (DGSM), has recently been updated in November 2016. Epidemiology, diagnostics, therapeutic procedures, and classification of sleep related disorders have been revised. Concerning epidemiology, a considerably higher mortality rate among pregnant women with OSA has been emphasized...
October 2017: Laryngo- Rhino- Otologie
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