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https://www.readbyqxmd.com/read/29151185/mercury-in-organs-of-pacific-walruses-odobenus-rosmarus-divergens-from-the-bering-sea
#1
Alexey M Trukhin, Mikhail V Simokon
The Pacific walrus (Odobenus rosmarus divergens) is still used as an important source of protein-rich food by indigenous peoples of Chukotka, Alaska, and other Arctic regions. Total mercury (THg) concentration was measured in eight internal organs of walruses. Samples were taken from 22 individuals (11 males and 11 females). Age of the animals ranged from 1 to 30 years. All the walruses were harvested by local hunters from the coastal waters off the Chukchi Peninsula (Russia) during the autumn of 2011. Total mercury concentration in the samples was determined by atomic absorption method...
November 18, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29150865/enhanced-mu-opioid-receptor-dependent-opioidergic-modulation-of-striatal-cholinergic-transmission-in-dyt1-dystonia
#2
Giulia Ponterio, Annalisa Tassone, Giuseppe Sciamanna, Valentina Vanni, Maria Meringolo, Massimo Santoro, Nicola Biagio Mercuri, Paola Bonsi, Antonio Pisani
BACKGROUND: Mu opioid receptor activation modulates acetylcholine release in the dorsal striatum, an area deeply involved in motor function, habit formation, and reinforcement learning as well as in the pathophysiology of different movement disorders, such as dystonia. Although the role of opioids in drug reward and addiction is well established, their involvement in motor dysfunction remains largely unexplored. METHODS: We used a multidisciplinary approach to investigate the responses to mu activation in 2 mouse models of DYT1 dystonia (Tor1a(+/Δgag) mice, Tor1a(+/-) torsinA null mice, and their respective wild-types)...
November 18, 2017: Movement Disorders: Official Journal of the Movement Disorder Society
https://www.readbyqxmd.com/read/29150503/carbon-amendments-alter-microbial-community-structure-and-net-mercury-methylation-potential-in-sediments
#3
Geoff A Christensen, Anil C Somenahally, James G Moberly, Carrie M Miller, Andrew J King, Cynthia C Gilmour, Steven D Brown, Mircea Podar, Craig C Brandt, Scott C Brooks, Anthony V Palumbo, Judy D Wall, Dwayne A Elias
Neurotoxic methylmercury (MeHg) is produced by anaerobic Bacteria and Archaea possessing the genes hgcAB, but it is unknown how organic substrate and electron acceptor availability impact the distribution and abundance of these organisms. We evaluated the impact of organic substrate amendments on mercury (Hg) methylation rates, microbial community structure, and the distribution of hgcAB(+) microbes with sediments. Sediment slurries were amended with short-chain fatty acids, alcohols, or a polysaccharide. Minimal increases in MeHg were observed following lactate, ethanol and methanol amendments while a significant decrease (∼70%) was observed with cellobiose incubations...
November 17, 2017: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/29150497/low-molecular-weight-thiols-and-thioredoxins-are-important-players-in-hg-ii-resistance-in-thermus-thermophilus-hb27
#4
J Norambuena, Y Wang, T Hanson, J M Boyd, T Barkay
Mercury (Hg), one of the most toxic and widely distributed heavy metals, has a high affinity for thiol groups. Thiol groups reduce and sequester Hg. Therefore, low molecular weight and protein thiols may be important cell components used in Hg resistance. To date, the role of low molecular weight thiols in Hg-detoxification remains understudied. The mercury resistance (mer) operon of Thermus thermophilus suggests an evolutionary link between Hg(II) resistance and low molecular weight thiol metabolism. This mer operon encodes for an enzyme involved in methionine biosynthesis, Oah...
November 17, 2017: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/29150340/placental-transfer-and-levels-of-mercury-selenium-vitamin-e-and-docosahexaenoic-acid-in-maternal-and-umbilical-cord-blood
#5
Mineshi Sakamoto, Hing Man Chan, José L Domingo, Chihaya Koriyama, Katsuyuki Murata
Methylmercury (MeHg) is a neurotoxicant known to affect the developing fetal brain as a sensitive target organ. As most mercury (Hg) in blood is MeHg, total mercury (THg) levels in blood are used to estimate the body burden of MeHg. The nutrients selenium (Se), vitamin E, and docosahexaenoic acid (DHA) are protective against MeHg toxicity. We compared maternal and cord blood concentrations of biochemical substances, THg and Se, vitamin E, DHA, and other elements, fatty acids, and amino acids in 54 Japanese mother-newborn pairs to elucidate the fetal risk of MeHg toxicity...
November 14, 2017: Environment International
https://www.readbyqxmd.com/read/29150339/hair-concentration-of-trace-elements-and-growth-in-homeless-children-aged-6years-results-from-the-enfams-study
#6
Lucia Fábelová, Stéphanie Vandentorren, Cécile Vuillermoz, Robert Garnier, Sandrine Lioret, Jérémie Botton
BACKGROUND: Growth is an important indicator of health in early childhood. This is a critical developmental period, during which a number of factors, including exposure to metals, might play a role in later physical and metabolic functions. OBJECTIVE: To study the association between exposure to arsenic (As), cadmium (Cd), mercury (Hg), lead (Pb) and selenium (Se), and physical growth of children from homeless families aged <6years. METHODS: This study was based on data of the cross-sectional survey (ENFAMS), which was conducted by the Observatoire du Samu Social on a random sample of homeless sheltered families in the Paris region during winter 2013...
November 14, 2017: Environment International
https://www.readbyqxmd.com/read/29149758/oligotrophy-as-a-major-driver-of-mercury-bioaccumulation-in-medium-to-high-trophic-level-consumers-a-marine-ecosystem-comparative-study
#7
Tiphaine Chouvelon, Pierre Cresson, Marc Bouchoucha, Christophe Brach-Papa, Paco Bustamante, Sylvette Crochet, Françoise Marco-Miralles, Bastien Thomas, Joël Knoery
Mercury (Hg) is a global contaminant of environmental concern. Numerous factors influencing its bioaccumulation in marine organisms have already been described at both individual and species levels (e.g., size or age, habitat, trophic level). However, few studies have compared the trophic characteristics of ecosystems to explain underlying mechanisms of differences in Hg bioaccumulation and biomagnification among food webs and systems. The present study aimed at investigating the potential primary role of the trophic status of systems on Hg bioaccumulation and biomagnification in temperate marine food webs, as shown by their medium-to high-trophic level consumers...
November 14, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/29149664/copper-phospholipid-interaction-at-cell-membrane-model-hydrophobic-surfaces
#8
Marina Mlakar, Vlado Cuculić, Sanja Frka, Blaženka Gašparović
Detailed investigation of Cu (II) binding with natural lipid phosphatidylglycerol (PG) in aqueous solution was carried out by voltammetric measurements at the mercury drop electrode, complemented by monolayer studies in a Langmuir trough and electrophoretic measurements, all used as models for hydrophobic cell membranes. Penetration of copper ions into the PG layer was facilitated by the formation of hydrophilic Cu-Phenanthroline (Phen) complex in the subphase, followed by the mixed ligand Cu-Phen-PG complex formation at the hydrophobic interface...
November 11, 2017: Bioelectrochemistry
https://www.readbyqxmd.com/read/29147740/geo-spatial-characterization-of-soil-mercury-and-arsenic-at-a-high-altitude-bolivian-gold-mine
#9
Glen D Johnson, Brian Pavilonis, Jack Caravanos, Jean Grassman
Soil mercury concentrations at a typical small-scale mine site in the Bolivian Andes were elevated (28-737 mg/kg or ppm) in localized areas where mercury amalgams were either formed or vaporized to release gold, but was not detectable beyond approximately 10 m from its sources. Arsenic was measurable, exceeding known background levels throughout the mine site (77-137,022 ppm), and was also measurable through the local village of Ingenio (36-1803 ppm). Although arsenic levels were high at all surveyed locations, its spatial pattern followed mercury, being highest where mercury was high...
November 16, 2017: Bulletin of Environmental Contamination and Toxicology
https://www.readbyqxmd.com/read/29147694/emerging-investigator-series-the-effect-of-wildfire-on-streamwater-mercury-and-organic-carbon-in-a-forested-watershed-in-the-southeastern-united-states
#10
Allison M Jensen, Todd M Scanlon, Ami L Riscassi
Wildfires alter forested ecosystems, which include large stores of mercury (Hg) and organic carbon, two compounds that are closely linked in vegetation, soils, and streamwater. Studies have shown that wildfires release elevated levels of mercury to the atmosphere which can be locally redeposited and leave charred organic material (vegetation and litter) on the soil surface. Both can contribute to the elevated mobilization of Hg into lakes and streams. However, no studies have conducted a detailed examination of hydrological transport of Hg following a wildfire...
November 17, 2017: Environmental Science. Processes & Impacts
https://www.readbyqxmd.com/read/29146212/the-current-environmental-levels-of-endocrine-disruptors-mercury-cadmium-organochlorine-pesticides-and-pcbs-in-a-belgian-adult-population-and-their-predictors-of-exposure
#11
Catherine Pirard, Stephanie Compere, Katty Firquet, Corinne Charlier
A human biomonitoring study was carried out measuring the levels of endocrine disruptors in 252 participants (18-76 years old) recruited between February and May 2015 from the general population of Liege Province (Belgium). In this study, we reported the recent levels of cadmium and mercury in urine, some organochlorine pesticides and polychlorinated biphenyls (PCBs) in serum, and their relations to demographic characteristics, lifestyle behaviors and dietary habits. The median urinary levels of mercury and cadmium were 0...
October 31, 2017: International Journal of Hygiene and Environmental Health
https://www.readbyqxmd.com/read/29146204/mercury-exposure-and-short-term-consequences-on-physiology-and-reproduction-in-antarctic-petrels
#12
Alice Carravieri, Jérôme Fort, Arnaud Tarroux, Yves Cherel, Oliver P Love, Solène Prieur, Maud Brault-Favrou, Paco Bustamante, Sébastien Descamps
Mercury (Hg) is a pervasive contaminant reaching Antarctic environments through atmospheric transport and deposition. Seabirds as meso to top predators can accumulate high quantities of Hg through diet. Reproduction is one of the most sensitive endpoints of Hg toxicity in marine birds. Yet, few studies have explored Hg exposure and effects in Antarctic seabirds, where increasing environmental perturbations challenge animal populations. This study focuses on the Antarctic petrel Thalassoica antarctica from Svarthamaren, Antarctica, where the world's largest breeding population is thought to be in decline...
November 13, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/29145616/variation-in-methylmercury-metabolism-and-elimination-status-mermes-in-humans-following-fish-consumption
#13
Samuel W Caito, Brian P Jackson, Tracy Punshon, Thomas Scrimale, Alex Grier, Steven R Gill, Tanzy M Love, Gene E Watson, Edwin van Wijngaarden, Matthew D Rand
Evaluating the potential for methylmercury (MeHg) toxicity relies on accurately predicting the mercury (Hg) body burden that results from eating fish. Hg body burden is directly determined by the slow elimination kinetics of MeHg in the human body (kel ∼0.014days-1 or t1/2∼ 50days). Existing studies on MeHg half-life in humans demonstrate a wide range values (t1/2 = 30 to > 150days) and has lead to uncertainty in the derivation of a regulatory standard for acceptable daily oral intake. The causes of variation in MeHg toxicokinetics in humans remain little explored...
November 14, 2017: Toxicological Sciences: An Official Journal of the Society of Toxicology
https://www.readbyqxmd.com/read/29145289/mercury-poisoning-through-intravenous-administration-two-case-reports-with-literature-review
#14
Qiuying Lu, Zilong Liu, Xiaorui Chen
RATIONALE: Metallic mercury poisoning through intravenous injection is rare, especially for a homicide attempt. Diagnosis and treatment of the disease are challenging. PATIENT CONCERNS: A 34-year-old male presented with pyrexia, chill, fatigue, body aches, and pain of the dorsal aspect of right foot. Another case is that of a 29-year-old male who committed suicide by injecting himself metallic mercury 15 g intravenously and presented with dizzy, dyspnea, fatigue, sweatiness, and waist soreness...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29145101/the-distribution-and-trends-of-persistent-organic-pollutants-and-mercury-in-marine-mammals-from-canada-s-eastern-arctic
#15
REVIEW
Tanya M Brown, Robie W Macdonald, Derek C G Muir, Robert J Letcher
Arctic contaminant research in the marine environment has focused on organohalogen compounds and mercury mainly because they are bioaccumulative, persistent and toxic. This review summarizes and discusses the patterns and trends of persistent organic pollutants (POPs) and mercury in ringed seals (Pusa hispida) and polar bears (Ursus maritimus) in the Eastern Canadian Arctic relative to the rest of the Canadian Arctic. The review provides explanations for these trends and looks at the implications of climate-related changes on contaminants in these marine mammals in a region that has been reviewed little...
November 13, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29143739/an-inaccurate-automated-device-negatively-impacts-the-diagnosis-and-treatment-of-gestational-hypertension
#16
Diane Nzelu, Felicia Yeung, Delphine Couderq, Andrew Shennan, Nikos A Kametas
OBJECTIVES: Automated blood pressure devices are frequently introduced in maternity care without prior validation for their accuracy in pregnancy. Our objectives were to, firstly, establish the accuracy in pregnancy of a locally used device (Welch Allyn 300) and, secondly, to audit its impact on the diagnosis and treatment of hypertension. STUDY DESIGN: Validation study: The device was evaluated using the grading criteria of the European Society of Hypertension International Protocol (ESH-IP) (2010)...
May 3, 2017: Pregnancy Hypertension
https://www.readbyqxmd.com/read/29140801/validation-of-the-microlife-bp-a3-pc-upper-arm-blood-pressure-monitor-in-patients-with-diabetes-mellitus-according-to-the-ansi-aami-iso-81060-2-2013-protocol
#17
Beate Beime, Ralf Krüger, Gertrud Hammel, Peter Bramlage, Cornelia Deutsch
OBJECTIVE: The aim of the present study was to validate the blood pressure (BP) measurement device, Microlife BP A3 PC, in patients with diabetes mellitus, according to the ANSI/AAMI/ISO 81060-2:2013 protocol. PATIENTS AND METHODS: In 85 individuals aged 56-88 years, with predefined criteria for diabetes mellitus, BP measurements on the upper arm were performed alternately using the Microlife BP A3 PC and a standard mercury reference sphygmomanometer. A total of 333 comparisons were included for analysis...
November 14, 2017: Blood Pressure Monitoring
https://www.readbyqxmd.com/read/29137843/-blood-pressure-in-a-native-tzotzil-population-from-the-state-of-chiapas-mexico
#18
Enrique Villarreal-García, Lourdes Verónica Villarreal-García
OBJECTIVE: To determine the blood pressure in a native Tzotzil population from the state of Chiapas, Mexico. METHODOLOGY: Cross-sectional study on a Chenalho Tzotzil population from Chiapas, Mexico, from August to December 2015, aged between 20 to 60 years-old. Patients with diabetes mellitus and hypertension were excluded, as well as pregnant patients. The sample size was 205, using as sample basis, the list of patients that went to the healthy patient wellness clinic...
November 11, 2017: Archivos de Cardiología de México
https://www.readbyqxmd.com/read/29137791/sonochemical-synthesis-and-characterization-of-new-seven-coordinated-zinc-cadmium-and-mercury-nitrate-complexes-new-precursors-for-nanostructure-metal-oxides
#19
S Mojahedi Jahromi, M Montazerozohori, A Masoudiasl, E Houshyar, S Joohari, J M White
The nitrate complexes of group 12 elements with a tridentate Schiff base ligand (L = (E)-N1-((E)-3- phenylallylidene)-N2-(2-((E)-((E)-3-phenylallylidene) amino)ethyl) ethane-1,2-diamine) were synthesized via sonochemical process and characterized by various physical and chemical methods. The structural analysis of the zinc nitrate complex by single crystal X-ray diffraction analysis shows that the central atom is seven-coordinated by three nitrogen atoms from the Schiff base ligand as well as four oxygen atoms from two different nitrate anions...
March 2018: Ultrasonics Sonochemistry
https://www.readbyqxmd.com/read/29136899/characterization-of-mercury-binding-proteins-in-human-neuroblastoma-sk-n-sh-cells-with-immobilized-metal-affinity-chromatography
#20
Yiling Li, Bin He, Ligang Hu, Xiu Huang, Zhaojun Yun, Runzeng Liu, Qunfang Zhou, Guibin Jiang
Metal-binding proteins play important roles in biological functions of metals. However, only very limited mercury-binding proteins with high abundance were characterized in cells or organisms. Characterization of mercury-binding proteins in proteome-wide is important for elucidating mechanisms of mercury toxicity comprehensively. In this study, a method based on immobilized mercury ion affinity chromatography was developed for identification of putative mercury-binding proteins. The method was then successfully applied to profile mercury-binding proteins in human neuroblastoma SK-N-SH cells...
February 1, 2018: Talanta
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