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https://www.readbyqxmd.com/read/29474214/chronic-pain-after-hysterectomy
#1
Birgitte Brandsborg, Lone Nikolajsen
PURPOSE OF REVIEW: Hysterectomy is a common surgical procedure with a low risk of major complications. However, some women experience long-lasting complications, including chronic postsurgical pain, which can have a negative impact on their quality of life. This review aims to present the recent literature on chronic pain following hysterectomy for benign indications. RECENT FINDINGS: Chronic pain following hysterectomy is reported in 10-50% of women. Risk factors include preoperative pelvic pain, pain elsewhere, acute postoperative pain, surgical procedure, and psychological factors such as anxiety and depression...
February 22, 2018: Current Opinion in Anaesthesiology
https://www.readbyqxmd.com/read/29471719/an-fmri-study-of-loneliness-in-younger-and-older-adults
#2
Alexandra E D'Agostino, David Kattan, Turhan Canli
Loneliness, the subjective experience of social isolation, may reflect, in part, underlying neural processing of social signals. Aging may exacerbate loneliness due to decreased social networks and increased social isolation, or it may reduce loneliness due to preferential attentional processing of positive information and increased interactions with emotionally close partners. Here, we conducted a functional magnetic resonance imaging (fMRI) study of loneliness in younger (N = 50, 26 female, Mage = 20.4) and older (N = 49, 30 female, Mage = 62...
February 23, 2018: Social Neuroscience
https://www.readbyqxmd.com/read/29471068/weight-loss-decreases-self-reported-appetite-and-alters-food-preferences-in-overweight-and-obese-adults-observational-data-from-the-diogenes-study
#3
Charlotte Andriessen, Pia Christensen, Lone Vestergaard Nielsen, Christian Ritz, Arne Astrup, Thomas Meinert Larsen, J Alfredo Martinez, Wim H M Saris, Marleen A van Baak, Angeliki Papadaki, Marie Kunesova, Susan Jebb, John Blundell, Clare Lawton, Anne Raben
People with obesity often struggle to maintain their weight loss after a weight loss period. Furthermore, the effect of weight loss on appetite and food preferences remains unclear. Hence this study investigated the effect of weight loss on subjective appetite and food preferences in healthy, overweight and obese volunteers. A subgroup of adult participants (n = 123) from the Diet Obesity and Genes (DiOGenes) study (subgroup A) was recruited from across six European countries. Participants lost ≥8% of initial body weight during an 8-week low calorie diet (LCD)...
February 19, 2018: Appetite
https://www.readbyqxmd.com/read/29470115/older-adults-social-relationships-and-health-care-utilization-a-systematic-review
#4
Nicole K Valtorta, Danielle Collingridge Moore, Lynn Barron, Daniel Stow, Barbara Hanratty
BACKGROUND: Deficiencies in older people's social relationships (including loneliness, social isolation, and low social support) have been implicated as a cause of premature mortality and increased morbidity. Whether they affect service use is unclear. OBJECTIVES: To determine whether social relationships are associated with older adults' use of health services, independently of health-related needs. SEARCH METHODS: We searched 8 electronic databases (MEDLINE, Embase, CINAHL, Web of Science, PsycINFO, Scopus, the Cochrane Library, and the Centre for Reviews and Dissemination) for data published between 1983 and 2016...
February 22, 2018: American Journal of Public Health
https://www.readbyqxmd.com/read/29469917/metamagnetism-stabilized-giant-magnetoelectric-coupling-in-ferroelectric-xbatio-3-1-x-bicoo-3-solid-solution
#5
Lokanath Patra, Zhao Pan, Jun Chen, Masaki Azuma, P Ravindran
In order to establish the correlation between the magnetoelectric coupling and magnetic instability, we have studied the structural, magnetic, and ferroelectric properties of BaTiO3 modified BiCoO3 i.e. xBaTiO3 -(1 - x)BiCoO3 as a function of BaTiO3 concentration (x) and volume from a series of general-gradient-corrected (GGA), GGA plus onsite Coulomb repulsion (U), full potential, spin-density-functional band-structure calculations within the framework of density functional theory along with synchrotron X-ray diffraction and magnetic measurement studies...
February 22, 2018: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/29467746/genomic-diversity-and-evolution-of-the-fish-pathogen-flavobacterium-psychrophilum
#6
Eric Duchaud, Tatiana Rochat, Christophe Habib, Paul Barbier, Valentin Loux, Cyprien Guérin, Inger Dalsgaard, Lone Madsen, Hanne Nilsen, Krister Sundell, Tom Wiklund, Nicole Strepparava, Thomas Wahli, Greta Caburlotto, Amedeo Manfrin, Gregory D Wiens, Erina Fujiwara-Nagata, Ruben Avendaño-Herrera, Jean-François Bernardet, Pierre Nicolas
Flavobacterium psychrophilum , the etiological agent of rainbow trout fry syndrome and bacterial cold-water disease in salmonid fish, is currently one of the main bacterial pathogens hampering the productivity of salmonid farming worldwide. In this study, the genomic diversity of the F. psychrophilum species is analyzed using a set of 41 genomes, including 30 newly sequenced isolates. These were selected on the basis of available MLST data with the two-fold objective of maximizing the coverage of the species diversity and of allowing a focus on the main clonal complex (CC-ST10) infecting farmed rainbow trout ( Oncorhynchus mykiss ) worldwide...
2018: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29467727/phase-variable-expression-of-a-single-phage-receptor-in-campylobacter-jejuni-nctc12662-influences-sensitivity-toward-several-diverse-cps-dependent-phages
#7
Yilmaz Emre Gencay, Martine C H Sørensen, Cory Q Wenzel, Christine M Szymanski, Lone Brøndsted
Campylobacter jejuni NCTC12662 is sensitive to infection by many Campylobacter bacteriophages. Here we used this strain to investigate the molecular mechanism behind phage resistance development when exposed to a single phage and demonstrate how phase variable expression of one surface component influences phage sensitivity against many diverse C. jejuni phages. When C. jejuni NCTC12662 was exposed to phage F207 overnight, 25% of the bacterial cells were able to grow on a lawn of phage F207, suggesting that resistance develops at a high frequency...
2018: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29467681/glutamate-levels-and-resting-cerebral-blood-flow-in-anterior-cingulate-cortex-are-associated-at-rest-and-immediately-following-infusion-of-s-ketamine-in-healthy-volunteers
#8
Kirsten Borup Bojesen, Kasper Aagaard Andersen, Sophie Nordahl Rasmussen, Lone Baandrup, Line Malmer Madsen, Birte Yding Glenthøj, Egill Rostrup, Brian Villumsen Broberg
Progressive loss of brain tissue is seen in some patients with schizophrenia and might be caused by increased levels of glutamate and resting cerebral blood flow (rCBF) alterations. Animal studies suggest that the normalisation of glutamate levels decreases rCBF and prevents structural changes in hippocampus. However, the relationship between glutamate and rCBF in anterior cingulate cortex (ACC) of humans has not been studied in the absence of antipsychotics and illness chronicity. Ketamine is a noncompetitive N -methyl-D-aspartate receptor antagonist that transiently induces schizophrenia-like symptoms and neurobiological disturbances in healthy volunteers (HVs)...
2018: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29464739/trigger-bond-analysis-of-nitroaromatic-energetic-materials-using-wiberg-bond-indices
#9
Ashley L Shoaf, Craig A Bayse
The identification of trigger bonds, bonds that break to initiate explosive decomposition, using computational methods could help direct the development of novel, "green" and efficient high energy density materials (HEDMs). Comparing bond densities in energetic materials to reference molecules using Wiberg bond indices (WBIs) provides a relative scale for bond activation (%ΔWBIs) to assign trigger bonds in a set of 63 nitroaromatic conventional energetic molecules. Intramolecular hydrogen bonding interactions enhance contributions of resonance structures that strengthen, or deactivate, the CNO2 trigger bonds and reduce the sensitivity of nitroaniline-based HEDMs...
February 21, 2018: Journal of Computational Chemistry
https://www.readbyqxmd.com/read/29460322/amide-neighbouring-group-effects-in-peptides-phenylalanine-as-relay-amino-acid-in-long-distance-electron-transfer
#10
Uta Wille, Joses Nathanael, Luke Gamon, Meike Cordes, Paul Rablen, Thomas Bally, Katharina Fromm, Bernd Giese
Nature uses proteins as medium for long-distance electron transfer (ET) to carry out redox reactions in distant compartments. This ET occurs either by a single-step superexchange or through a multi-step charge hopping process, which uses side chains of amino acids as stepping stones. In this study we demonstrate that Phe can act as a relay amino acid for long-distance electron hole transfer through peptides. The considerably increased susceptibility of the aromatic ring to oxidation is caused by the lone pairs of neighbouring amide carbonyl groups, which stabilize the Phe radical cation...
February 19, 2018: Chembiochem: a European Journal of Chemical Biology
https://www.readbyqxmd.com/read/29460321/factors-associated-with-delayed-infant-immunization-in-a-nationally-representative-cohort-study
#11
J Homel, B Edwards
BACKGROUND: Many children in developed countries do not receive recommended vaccines on time. However, knowledge about factors related to timeliness remains limited. Quantifying the relative impact of parental attitudes compared with socio-demographic factors for delayed immunization would inform policy responses. METHODS: Participants in the nationally representative Longitudinal Study of Australian Children were matched with their vaccination histories in the Australian Childhood Immunisation Register (N = 4,121)...
February 20, 2018: Child: Care, Health and Development
https://www.readbyqxmd.com/read/29459916/uv-induced-long-lived-decays-in-solvated-pyrimidine-nucleosides-resolved-at-the-ms-caspt2-mm-level
#12
Ana Julieta Pepino, Javier Segarra-Martí, Artur Nenov, Ivan Rivalta, Roberto Improta, Marco Garavelli
The most relevant 'dark' electronic excited states in DNA/RNA pyrimidine nucleosides are mapped in water employing hybrid MS-CASPT2/MM optimisations with explicit solvation and including the sugar. Conical intersections (CIs) between initially accessed bright1 ππ* and the lowest energy dark1 nπ* excited states, involving the lone pair localised on the oxygen and/or nitrogen atoms are characterised. They are found in the vicinities of the Franck-Condon (FC) region and are shown to facilitate non-adiabatic population transfer...
February 20, 2018: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/29455790/insertion-deletion-polymorphism-of-ace-gene-in-females-with-peripartum-cardiomyopathy-a-case-control-study
#13
Irfan Yaqoob, Nisar A Tramboo, Irfan A Bhat, Arshad Pandith, Jahangir R Beig, Imran Hafeez, Aijaz A Lone, Tariq R Shah, Sumera Samreen
BACKGROUND: The role of polymorphism of Angiotensin converting enzyme (ACE) gene and ACE activity in etiopathogenesis, prognosis, and many other clinical parameters in the various form of the cardiovascular disease has been established to some degree of certainty. The pathophysiology of Peripartum cardiomyopathy (PPCM) remains an area of active research. The main aim of our study was to see pattern of ACE- Insertion/Deletion (I/D) allele in PPCM and its implications on left ventricular performance indices...
January 2018: Indian Heart Journal
https://www.readbyqxmd.com/read/29449506/whole-body-magnetic-resonance-imaging-in-axial-spondyloarthritis-reduction-of-sacroiliac-spinal-and-entheseal-inflammation-in-a-placebo-controlled-trial-of-adalimumab
#14
Simon Krabbe, Mikkel Østergaard, Iris Eshed, Inge J Sørensen, Bente Jensen, Jakob M Møller, Lone Balding, Ole R Madsen, Karsten Asmussen, Grith Eng, Niklas R Jørgensen, Susanne J Pedersen
OBJECTIVE: To investigate whether adalimumab (ADA) reduces whole-body (WB-) magnetic resonance imaging (MRI) indices for inflammation in the entheses, peripheral joints, sacroiliac joints, spine, and the entire body in patients with axial spondyloarthritis (axSpA). METHODS: An investigator-initiated, randomized, placebo-controlled, double-blinded 48-week followup trial included 49 patients with axSpA, who had Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) ≥ 4...
February 15, 2018: Journal of Rheumatology
https://www.readbyqxmd.com/read/29448692/preparation-of-caco%C3%A2-and-cao-nanoparticles-via-solid-state-conversion-of-calcium-oleate-precursor
#15
Raji Atchudan, Nasreena Lone, Jin Joo
Calcium carbonate (CaCO3) and monodisperse calcium oxide nanoparticles (CaO NPs) are prepared by the calcination of solid-state calcium oleate precursor in air condition. The effect of calcination temperature on the synthesis of CaCO3 and CaO NPs is examined. The polymorphism is confirmed by X-ray diffraction spectroscopy (XRD), Fourier transform infrared spectroscopy (FTIR), and thermogravimetric analysis (TGA). The sample morphologies including their size and size distribution are investigated by field emission scanning electron microscopy (FESEM)...
March 1, 2018: Journal of Nanoscience and Nanotechnology
https://www.readbyqxmd.com/read/29444832/differential-contributions-of-specimen-types-culturing-and-16s-rrna-sequencing-in-diagnosis-of-prosthetic-joint-infections
#16
Lone Heimann Larsen, Vesal Khalid, Yijuan Xu, Trine Rolighed Thomsen, Henrik C Schønheyder
Prosthetic joint failure is mainly caused by infection, aseptic failure (AF), and mechanical problems. Infection detection has been improved with modified culture methods and molecular diagnostics. However, comparisons between modified and conventional microbiology methods are difficult, due to variations in specimen sampling. In this prospective, multidisciplinary study of hip or knee prosthetic failures, we assessed the contributions of different specimen types, extended culture incubations, and 16S rRNA sequencing for diagnosing prosthetic joint infections (PJI)...
February 14, 2018: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/29444400/chiral-nickel-ii-complex-catalyzed-enantioselective-doyle-kirmse-reaction-of-%C3%AE-diazo-pyrazoleamides
#17
Xiaobin Lin, Yu Tang, Wei Yang, Fei Tan, Lili Lin, Xiaohua Liu, Xiaoming Feng
Although high enantioselectivity of [2,3]-sigmatropic rearrangement of sulfonium ylides (Doyle-Kirmse reaction) has proven surprisingly elusive using classic chiral Rh(II) and Cu(I) catalysts, in principle it is due to the difficulty in fine discrimination of the heterotopic lone pairs of sulfur and chirality inversion at sulfur of sulfonium ylides. Here, we show that the synergistic merger of new α-diazo pyrazoleamides and chiral N,N'-dioxide-nickel(II) complex catalyst enables a highly enantioselective Doyle-Kirmse reaction...
February 14, 2018: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/29439003/impact-of-red-and-processed-meat-and-fibre-intake-on-treatment-outcomes-among-patients-with-chronic-inflammatory-diseases-protocol-for-a-prospective-cohort-study-of-prognostic-factors-and-personalised-medicine
#18
Robin Christensen, Berit L Heitmann, Karina Winther Andersen, Ole Haagen Nielsen, Signe Bek Sørensen, Mohamad Jawhara, Anette Bygum, Lone Hvid, Jakob Grauslund, Jimmi Wied, Henning Glerup, Ulrich Fredberg, Jan Alexander Villadsen, Søren Geill Kjær, Jan Fallingborg, Seyed A G R Moghadd, Torben Knudsen, Jacob Brodersen, Jesper Frøjk, Jens Frederik Dahlerup, Anders Bo Bojesen, Grith Lykke Sorensen, Steffen Thiel, Nils J Færgeman, Ivan Brandslund, Tue Bjerg Bennike, Allan Stensballe, Erik Berg Schmidt, Andre Franke, David Ellinghaus, Philip Rosenstiel, Jeroen Raes, Mette Boye, Lars Werner, Charlotte Lindgaard Nielsen, Heidi Lausten Munk, Anders Bathum Nexøe, Torkell Ellingsen, Uffe Holmskov, Jens Kjeldsen, Vibeke Andersen
INTRODUCTION: Chronic inflammatory diseases (CIDs) are frequently treated with biological medications, specifically tumour necrosis factor inhibitors (TNFi)). These medications inhibit the pro-inflammatory molecule TNF alpha, which has been strongly implicated in the aetiology of these diseases. Up to one-third of patients do not, however, respond to biologics, and lifestyle factors are assumed to affect treatment outcomes. Little is known about the effects of dietary lifestyle as a prognostic factor that may enable personalised medicine...
February 8, 2018: BMJ Open
https://www.readbyqxmd.com/read/29437260/tetrylones-an-intriguing-class-of-monoatomic-zerovalent-group-14-compounds
#19
Paresh Kumar Majhi, Takahiro Sasamori
Tetrylones (ylidones) represent a class of zero-valent group-14 compounds with the general formula EL2 (E = C, Si, Ge, Sn, or Pb; L = neutral sigma-donating ligand), wherein the tetrel atom, E(0), possess its four valence electrons in the form of two electron lone pairs, and is moreover coordinated by two ligands (L) via donor-acceptor interactions (LEL). This review focuses on the synthesis, structure, reactivity, and computational examination of the isolable heavier tetrylones (Si, Ge, Sn) that have been discovered recently...
February 13, 2018: Chemistry: a European Journal
https://www.readbyqxmd.com/read/29431245/how-does-a-container-affect-acidity-of-its-content-charge-depletion-bonding-inside-fullerenes
#20
Adam Jaros, Zahra Badri, Pankaj Lochan Bora, Esmaeil Farajpour Bonab, Radek Marek, Michal Straka, Cina Foroutan-Nejad
A recent study (Sci. Adv. 2017, 3, e1602833) has shown that FH…OH2 hydrogen bond in a HF·H2O pair substantially shortens and the H-F bond elongates upon encapsulation of the cluster in C70 fullerene. This has been attributed to compression of the HF·H2O pair inside the cavity of C70. Here we present theoretical evidence that the effect is not caused by a mere compression of the H2O·HF pair but it is related to a strong lone-pair-π (LP-π) bonding with the fullerene cage. To support this argument, a systematic electronic structure study of selected small molecules (HF, H2O, and NH3) and their pairs enclosed in fullerene cages (C60, C70, and C90) has been performed...
February 12, 2018: Chemistry: a European Journal
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