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https://www.readbyqxmd.com/read/29670568/the-dynamics-of-concussion-mapping-pathophysiology-persistence-and-recovery-with-causal-loop-diagramming
#1
Erin S Kenzie, Elle L Parks, Erin D Bigler, David W Wright, Miranda M Lim, James C Chesnutt, Gregory W J Hawryluk, Wayne Gordon, Wayne Wakeland
Despite increasing public awareness and a growing body of literature on the subject of concussion, or mild traumatic brain injury, an urgent need still exists for reliable diagnostic measures, clinical care guidelines, and effective treatments for the condition. Complexity and heterogeneity complicate research efforts and indicate the need for innovative approaches to synthesize current knowledge in order to improve clinical outcomes. Methods from the interdisciplinary field of systems science, including models of complex systems, have been increasingly applied to biomedical applications and show promise for generating insight for traumatic brain injury...
2018: Frontiers in Neurology
https://www.readbyqxmd.com/read/29648976/adherence-to-brain-trauma-foundation-guidelines-for-management-of-traumatic-brain-injury-patients-and-its-effect-on-outcomes-systematic-review
#2
Yahya Khormi, Ibrahim Gosadi, Sandy Campbell, Ambikaipakan Senthilselvan, Cian O'Kelly, David Zygun
Traumatic brain injury (TBI) management based on Brain Trauma Foundation (BTF) guidelines is widely accepted and thought to improve outcome. The objectives of this study are to provide an overview of adherence to BTF guidelines and to explore which factors influence adherence. We conducted a search of relevant electronic bibliographic databases. Twenty articles met inclusion/exclusion criteria out of 666 papers screened. All were cohort studies. Wide variation in adherence to BTF guidelines was observed with a median of 66...
March 6, 2018: Journal of Neurotrauma
https://www.readbyqxmd.com/read/29648972/randomized-controlled-trials-in-adult-traumatic-brain-injury-a-systematic-review-on-the-use-and-reporting-of-clinical-outcome-assessments
#3
Lindsay Horton, Jonathan Rhodes, Lindsay Wilson
As part of efforts to improve study design, the use of outcome measures in randomized controlled trials (RCTs) in traumatic brain injury (TBI) is receiving increasing attention. This review aimed to assess how clinical outcome assessments (COAs) have been used and reported in RCTs in adult TBI. Systematic literature searches were conducted to identify medium to large (n ≥ 100) acute and post-acute TBI trials published since 2000. Data were extracted independently by two reviewers using a set of structured templates...
March 3, 2018: Journal of Neurotrauma
https://www.readbyqxmd.com/read/29627171/comparison-of-nicardipine-with-clevidipine-in-the-management-of-hypertension-in-acute-cerebrovascular-diseases
#4
Zachary Rosenfeldt, Katelyn Conklen, Breck Jones, Don Ferrill, Maithili Deshpande, Fazeel M Siddiqui
BACKGROUND AND PURPOSE: In acute stroke, hypertension worsens outcomes. Guidelines do not mention a preferred antihypertensive agent. This present study aimed to compare the efficacy and safety of nicardipine and clevidipine in acute stroke. METHODS: This retrospective review compared nicardipine with clevidipine for hypertension in acute stroke patients from March 17, 2015 to December 23, 2016. Ischemic and hemorrhagic stroke types were evaluated. Patients were excluded if under 18 years, had traumatic brain injury, had intracranial neoplasm, were on dialysis, had both study drugs during the stroke admission, or the study drug was infused for less than 1 hour...
April 4, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/29597083/traumatic-brain-injury-and-receipt-of-prescription-opioid-therapy-for-chronic-pain-in-iraq-and-afghanistan-veterans-do-clinical-practice-guidelines-matter
#5
Karen H Seal, Daniel Bertenthal, Deborah E Barnes, Amy L Byers, Carolyn J Gibson, Kristine Yaffe
Clinical practice guidelines admonish against prescribing opioids for individuals with chronic pain and traumatic brain injury (TBI) given increased risk for adverse outcomes, yet no studies have described opioid prescribing patterns in these higher risk patients. Between October 2007 and March 2015, 53,124 Iraq and Afghanistan veterans with chronic pain not prescribed opioids in the previous year were followed for one year after completing a Comprehensive TBI Evaluation (CTBIE) within Department of Veterans Affairs health care facilities...
March 26, 2018: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/29596291/interprofessional-simulations-promote-knowledge-retention-and-enhance-perceptions-of-teamwork-skills-in-a-surgical-trauma-burn-intensive-care-unit-setting
#6
Katie L George, Beth Quatrara
BACKGROUND: The current state of health care encompasses highly acute, complex patients, managed with ever-changing technology. The ability to function proficiently in critical care relies on knowledge, technical skills, and interprofessional teamwork. Integration of these factors can improve patient outcomes. Simulation provides "hands-on" practice and allows for the integration of teamwork into knowledge/skill training. However, simulation can require a significant investment of time, effort, and financial resources...
May 2018: Dimensions of Critical Care Nursing: DCCN
https://www.readbyqxmd.com/read/29557322/is-concussion-a-risk-factor-for-epilepsy
#7
Richard Wennberg, Carmen Hiploylee, Peter Tai, Charles H Tator
BACKGROUND: Epidemiologic studies have suggested that concussion, or mild traumatic brain injury (mTBI), is associated with a twofold or greater increase in relative risk for the development of post-traumatic epilepsy. To assess the clinical validity of these findings, we analyzed the incidence of epilepsy in a large cohort of post-concussion patients in whom concussion was strictly defined according to international guidelines. METHODS: A retrospective cohort study of 330 consecutive post-concussion patients followed by a single concussion specialist...
March 20, 2018: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://www.readbyqxmd.com/read/29555178/the-latest-french-guidelines-for-the-management-in-the-first-24hours-of-patients-with-severe-traumatic-brain-injury-tbi-translating-limited-science-evidence-into-robust-practical-recommendations
#8
EDITORIAL
https://www.readbyqxmd.com/read/29547998/damage-control-resuscitation-supplemented-with-vasopressin-in-a-severe-polytrauma-model-with-traumatic-brain-injury-and-uncontrolled-internal-hemorrhage
#9
J Michael Dickson, Xu Wang, Alexander E St John, Esther B Lim, Susan A Stern, Nathan J White
Introduction: Traumatic brain injury (TBI) and hemorrhagic shock (HS) are the leading causes of traumatic death worldwide and particularly on the battlefield. They are especially challenging when present simultaneously (polytrauma), and clear blood pressure end points during fluid resuscitation are not well described for this situation. The goal of this study is to evaluate for any benefit of increasing blood pressure using a vasopressor on brain blood flow during initial fluid resuscitation in a swine polytrauma model...
March 14, 2018: Military Medicine
https://www.readbyqxmd.com/read/29530681/strategies-in-traumatic-brain-injury-and-alcohol-consumption-a-professional-s-survey
#10
Rodrigo Ramos-Zúñiga, Elizabeth Sevilla, Yara Ursiel-Ortega
OBJETIVE: Traumatic Brain Injury (TBI) associated to alcohol consumption is a global public health problem. It is important to identify and rethink the strategies to approach this challenge for health institutions from a professional perspective. METHODS: An online survey, created with google forms, was sent to professional neurosurgeons in Mexico and Latin America. Participation was voluntary, and the responses were anonymous and confidential. Data were captured after a month and subjected to descriptive statistical analysis using Fisher's method and Chi Square...
March 9, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29530228/the-use-of-ct-in-the-management-of-minor-head-injuries-in-queenstown
#11
Jennifer Keys, Louise Venter, Garry Nixon
AIM This study retrospectively reviewed the management of head injury at Lakes District Hospital in Queenstown, New Zealand. The aim is to describe the management of minor head injury with particular reference to the current Traumatic Brain Injury guidelines of the New Zealand Guidelines Group. METHODS We identified all patients with head injury as a primary diagnosis who were seen in the Emergency Department at Lakes District Hospital during 2013-2015. We recorded clinical criteria indicating need for computed tomography (CT) scanning according to current guidelines for management of minor head injury...
June 2017: Journal of Primary Health Care
https://www.readbyqxmd.com/read/29518211/letter-guidelines-for-the-management-of-severe-traumatic-brain-injury-fourth-edition
#12
Venkatapura J Ramesh, Dhritiman Chakrabarti
No abstract text is available yet for this article.
March 5, 2018: Neurosurgery
https://www.readbyqxmd.com/read/29515808/seizure-prophylaxis-in-the-neuroscience-intensive-care-unit
#13
REVIEW
Sushma Yerram, Nakul Katyal, Keerthivaas Premkumar, Premkumar Nattanmai, Christopher R Newey
Background: Seizures are a considerable complication in critically ill patients. Their incidence is significantly high in neurosciences intensive care unit patients. Seizure prophylaxis with anti-epileptic drugs is a common practice in neurosciences intensive care unit. However, its utility in patients without clinical seizure, with an underlying neurological injury, is somewhat controversial. Body: In this article, we have reviewed the evidence for seizure prophylaxis in commonly encountered neurological conditions in neurosciences intensive care unit and discussed the possible prognostic role of continuous electroencephalography monitoring in detecting early seizures in critically ill patients...
2018: Journal of Intensive Care
https://www.readbyqxmd.com/read/29504354/outcome-of-traumatic-brain-injury-in-children-by-using-rotterdam-score-on-computed-tomography
#14
Anwarul Haque, Zehra Dhanani, Amin Ali, Basit Salam, Qalab Abbas, Gohar Javed, Humaira Jurair
BACKGROUND: The Rotterdam Score (RS) on CT head is a new evolving clinical tool as a predictor of mortality in Traumatic Brain Injury (TBI). The objective of this study is to assess the outcome of children with TBI admitted in paediatric intensive care unit (PICU) of a tertiary-care, university hospital by using RS. METHODS: This was a prospective observational study conducted on children (age: 1mo -16yr) with TBI admitted in PICU of Aga Khan University Hospital from 2013 to 2016...
January 2018: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/29492561/what-do-we-mean-by-cerebral-perfusion-pressure
#15
Bart Depreitere, Geert Meyfroidt, Fabian Güiza
INTRODUCTION: No consensus exists on the exact method for measuring mean arterial blood pressure (MAP) in the definition of cerebral perfusion pressure (CPP). The aim of the current study is to investigate how different MAP measurement methods have influenced the CPP recommendations in the Brain Trauma Foundation (BTF) guidelines. METHODS: All papers on which the chapter on CPP thresholds in the 2007 version of the BTF guidelines is based, were reviewed. If accurate descriptions of head of bed elevation and arterial pressure transducer height were lacking, the authors were emailed for clarification...
2018: Acta Neurochirurgica. Supplement
https://www.readbyqxmd.com/read/29492521/cerebral-perfusion-pressure-variability-between-patients-and-between-centres
#16
Bart Depreitere, Fabian Güiza, Ian Piper, Giuseppe Citerio, Iain Chambers, Patricia A Jones, Tsz-Yan M Lo, Per Enblad, Pelle Nilsson, Bart Feyen, Philippe Jorens, Andrew Maas, Martina U Schuhmann, Rob Donald, Laura Moss, Greet Van den Berghe, Geert Meyfroidt
INTRODUCTION:  The aim of this analysis was to investigate to what extent median cerebral perfusion pressure (CPP) differs between severe traumatic brain injury (TBI) patients and between centres, and whether the 2007 change in CPP threshold in the Brain Trauma Foundation guidelines is reflected in patient data collected at several centres over different time periods. METHODS:  Data were collected from the Brain-IT database, a multi-centre project between 2003 and 2005, and from a recent project in four centres between 2009 and 2013...
2018: Acta Neurochirurgica. Supplement
https://www.readbyqxmd.com/read/29490958/systematic-review-of-clinical-practice-guidelines-to-identify-recommendations-for-rehabilitation-after-stroke-and-other-acquired-brain-injuries
#17
Laura Jolliffe, Natasha A Lannin, Dominique A Cadilhac, Tammy Hoffmann
OBJECTIVES: Rehabilitation clinical practice guidelines (CPGs) contain recommendation statements aimed at optimising care for adults with stroke and other brain injury. The aim of this study was to determine the quality, scope and consistency of CPG recommendations for rehabilitation covering the acquired brain injury populations. DESIGN: Systematic review. INTERVENTIONS: Included CPGs contained recommendations for inpatient rehabilitation or community rehabilitation for adults with an acquired brain injury diagnosis (stroke, traumatic or other non-progressive acquired brain impairments)...
February 28, 2018: BMJ Open
https://www.readbyqxmd.com/read/29473174/variation-in-red-cell-transfusion-decisions-in-the-intensive-care-unit-a-nationwide-survey-in-the-netherlands
#18
F J Kranenburg, S A Willems, S Le Cessie, P J Marang-van de Mheen, J G van der Bom, M S Arbous
BACKGROUND AND OBJECTIVES: Most guidelines recommend a restrictive transfusion trigger of 7 g/dl. It is unclear whether this resulted in more uniform transfusion practices. The primary objective was to uncover the extent of variation in transfusion decisions within four scenarios of critically ill patients among critical care physicians in the Netherlands. MATERIALS AND METHODS: An online survey comprising four different hypothetical clinical scenarios was sent to all members of the Dutch Society of Intensive Care...
February 23, 2018: Vox Sanguinis
https://www.readbyqxmd.com/read/29462640/blood-biomarkers-in-paediatric-mild-traumatic-brain-injury-a-systematic-review
#19
REVIEW
Micaela Lugones, Georgia Parkin, Stefan Bjelosevic, Michael Takagi, Cathriona Clarke, Vicki Anderson, Vera Ignjatovic
OBJECTIVE: To summarize all current studies focusing on blood biomarkers in paediatric mild traumatic brain injury (mTBI) and to outline the possible use of blood biomarkers for diagnostic, prognostic and monitoring purposes within this setting. METHODS: A systematic review following the PRISMA guidelines was conducted using the MEDLINE, PubMed and EMBASE databases. RESULTS: A total of 21 studies were included in the review, encompassing a total of 14 different biomarkers...
February 17, 2018: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/29461428/cervical-spine-imaging-and-injuries-in-young-children-with-non-motor-vehicle-crash-associated-traumatic-brain-injury
#20
M Katherine Henry, Benjamin French, Chris Feudtner, Mark R Zonfrillo, Daniel M Lindberg, James D Anderst, Rachel P Berger, Joanne N Wood
OBJECTIVES: The aim of this study was to evaluate cervical magnetic resonance imaging (MRI) and computed tomography (CT) practices and cervical spine injuries among young children with non-motor vehicle crash (MVC)-associated traumatic brain injury (TBI). METHODS: We performed a retrospective study of a stratified, systematic random sample of 328 children younger than 2 years with non-MVC-associated TBI at 4 urban children's hospitals from 2008 to 2012. We defined TBI etiology as accidental, indeterminate, or abuse...
February 15, 2018: Pediatric Emergency Care
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