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https://www.readbyqxmd.com/read/28335404/perceptions-of-health-co-benefits-in-relation-to-greenhouse-gas-emission-reductions-a-survey-among-urban-residents-in-three-chinese-cities
#1
Jinghong Gao, Guozhang Xu, Wenjun Ma, Yong Zhang, Alistair Woodward, Sotiris Vardoulakis, Sari Kovats, Paul Wilkinson, Tianfeng He, Hualiang Lin, Tao Liu, Shaohua Gu, Jun Wang, Jing Li, Jun Yang, Xiaobo Liu, Jing Li, Haixia Wu, Qiyong Liu
Limited information is available on the perceptions of stakeholders concerning the health co-benefits of greenhouse gas (GHG) emission reductions. The purpose of this study was to investigate the perceptions of urban residents on the health co-benefits involving GHG abatement and related influencing factors in three cities in China. Beijing, Ningbo and Guangzhou were selected for this survey. Participants were recruited from randomly chosen committees, following quotas for gender and age in proportion to the respective population shares...
March 13, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28326542/current-and-future-therapies-for-addressing-the-effects-of-inflammation-on-hdl-cholesterol-metabolism
#2
REVIEW
Fatima Iqbal, Wendy S Baker, Madiha I Khan, Shwetha Thukuntla, Kevin H McKinney, Nicola Abate, Demidmaa Tuvdendorj
Cardiovascular disease (CVD) is a major cause of morbidity and mortality worldwide. Inflammatory processes arising from metabolic abnormalities are known to precipitate the development of CVD. Several metabolic and inflammatory markers have been proposed for predicting the progression of CVD, including high density lipoprotein cholesterol (HDL-C). For ~50 years, HDL-C has been considered as the atheroprotective 'good' cholesterol because of its strong inverse association with the progression of CVD. Thus, interventions to increase the concentration of HDL-C have been successfully tested in animals; however, clinical trials were unable to confirm the cardiovascular benefits of pharmaceutical interventions aimed at increasing HDL-C levels...
March 22, 2017: British Journal of Pharmacology
https://www.readbyqxmd.com/read/28326350/tumor-induced-osteomalacia-secondary-to-anaplastic-thyroid-carcinoma-a-case-report-and-review-of-the-literature
#3
Ejigayehu G Abate, Victor Bernet, Cherise Cortese, Hillary W Garner
CONTEXT: Tumor induced osteomalacia related to anaplastic thyroid cancer has never been reported. OBJECTIVE: We describe a case of tumor induced osteomalacia (TIO) in a patient with a fibroblast growth factor 23 (FGF-23) secreting anaplastic thyroid carcinoma. The current imaging modalities are reviewed. DESIGN AND INTERVENTION: Clinical, biochemical, and radiological assessments were done, including computer tomography (CT) of the neck and skull to thigh positron emission tomography (PET)/CT...
December 2016: Bone Reports
https://www.readbyqxmd.com/read/28325855/pretreatment-with-aldh2-agonist-alda-1-reduces-intestinal-injury-induced-by-ischemia-and-reperfusion-in-mice
#4
Qiankun Zhu, Guizhen He, Jie Wang, Yukang Wang, Wei Chen
Many studies demonstrate that activation of aldehyde dehydrogenase 2 (ALDH2) is protective against oxidative stress via detoxification of cytotoxic aldehydes and could attenuate cardiac, cerebral, lung, and renal ischemia reperfusion (IR) injuries. However, the effect of ALDH2 in intestinal IR is unknown. This study was to determine whether ALDH2 agonist, Alda-1, could alleviate intestinal injury after gut IR. In a mice model of intestinal IR injury, histological grading, proinflammatory cytokines, oxidative stress, cellular apoptosis, chemokine contents, ALDH2 activity, 4-HNE and MDA were evaluated...
March 21, 2017: Clinical Science (1979-)
https://www.readbyqxmd.com/read/28325593/agriculture-and-climate-change-potential-for-mitigation-in-spain
#5
Jose Albiac, Taher Kahil, Eduardo Notivol, Elena Calvo
Agriculture and forestry activities are one of the many sources of greenhouse gas (GHG) emissions, but they are also sources of low-cost opportunities to mitigate these emissions compared to other economic sectors. This paper provides a first estimate of the potential for mitigation in the whole Spanish agriculture. A set of mitigation measures are selected for their cost-effectiveness and abatement potential and an efficient mix of these measures is identified with reference to a social cost of carbon of 40 €/tCO2e...
March 18, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28322712/implementation-and-initial-analysis-of-a-laboratory-based-weekly-biosurveillance-system-provence-alpes-c%C3%A3-te-d-azur-france
#6
Michael Huart, Gabriel Bedubourg, Cédric Abat, Philippe Colson, Jean Marc Rolain, Hervé Chaudet, Pierre Edouard Fournier, Didier Raoult, Xavier Deparis
We describe the implementation of an automated infectious disease surveillance system that uses data collected from 210 microbiologic laboratories throughout the Provence-Alpes-Côte d'Azur region in France. Each week, these facilities report bacterial species that have been isolated from patients in their area. An alarm is triggered whenever the case count for a bacterial species infection exceeds 2 SDs of the historical mean for that species at the participating laboratory. At its inception in July 2013, the system monitored 611 bacterial species...
April 2017: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/28320859/2-arachidonoylglycerol-ameliorates-inflammatory-stress-induced-insulin-resistance-in-cardiomyocytes
#7
Dipanjan Chanda, Yvonne Oligschlaeger, Ilvy Geraets, Yilin Liu, Xiaoqing Zhu, Jieyi Li, Miranda Nabben, Will Coumans, Joost J F P Luiken, Jan F C Glatz, Dietbert Neumann
Several studies have linked impaired glucose uptake and insulin resistance (IR) to functional impairment of the heart. Recently, endocannabinoids have been implicated in cardiovascular disease. However, the mechanisms involving endocannabinoid signaling, glucose uptake and IR in cardiomyocytes are understudied. Here, we report the endocannabinoid 2-Arachidonoylglycerol (2-AG) via stimulation of cannabinoid type-1 (CB1) receptor and Ca2+/Calmodulin-dependent protein kinase β (CaMKKβ) activates AMPK leading to increased glucose uptake...
March 20, 2017: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/28320049/d-%C3%AE-hydroxybutyrate-promotes-functional-recovery-and-relieves-pain-hypersensitivity-in-mice-with-spinal-cord-injury
#8
Jiao Qian, Wenjun Zhu, Ming Lu, Bin Ni, Jun Yang
BACKGROUND AND PURPOSE: Spinal cord injury (SCI) leads to severe motor and sensory dysfunction and significantly reduces the quality of life. The aim of present work was to investigate the effect of administration of exogenous D-β-hydroxybutyrate (DBHB) on functional recovery and neuropathic pain in spinal-cord-injured mice. EXPERIMENTAL APPROACH: Mice were given a moderate-severe thoracic spinal contusion injury at the T9-10 level, and treated with exogenous DBHB...
March 20, 2017: British Journal of Pharmacology
https://www.readbyqxmd.com/read/28319485/recent-trends-in-the-prevalence-of-chronic-kidney-disease-not-the-same-old-song
#9
Raymond K Hsu, Neil R Powe
PURPOSE OF REVIEW: We aim to review recent updates on the epidemiology of chronic kidney disease (CKD). RECENT FINDINGS: Recent analyses from the National Health and Nutritional Examination survey describe the temporal trend in CKD prevalence in US adults. The overall prevalence of estimated glomerular filtration rate less than 60 ml/min/1.73 m increased from 4.8% in 1988-1994 to 6.9% in 2003-2004, but has since stabilized at 6.4-6.9% up to 2011-2012. Prevalence of CKD stages 1-4 has also stabilized at ∼14% of adults since 2003-2004...
March 17, 2017: Current Opinion in Nephrology and Hypertension
https://www.readbyqxmd.com/read/28318790/wood-burning-pollution-in-southern-chile-pm2-5-source-apportionment-using-cmb-and-molecular-markers
#10
Ana M Villalobos, Francisco Barraza, Héctor Jorquera, James J Schauer
Temuco is a mid-size city representative of severe wood smoke pollution in southern Chile; i.e., ambient 24-h PM2.5 concentrations have exceeded 150 μg/m(3) in the winter season and the top concentration reached 372 μg/m(3) in 2010. Annual mean concentrations have decreased but are still above 30 μg/m(3). For the very first time, a molecular marker source apportionment of ambient organic carbon (OC) and PM2.5 was conducted in Temuco. Primary resolved sources for PM2.5 were wood smoke (37.5%), coal combustion (4...
March 16, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28317441/oxidative-degradation-of-pentachlorophenol-by-permanganate-for-isco-application
#11
Roger Matta, Serge Chiron
Potassium permanganate (KMnO4) has been an effective technology for the in situ chemical oxidation (ISCO) of many organic compounds including chlorinated alkanes and alkenes, but it has rarely been applied for oxidizing aromatic organochlorines. This study confirms the ability of permanganate to oxidize an aromatic chlorinated compound, pentachlorophenol (PCP), in an efficient manner at neutral pH. The rate of the reaction between KMnO4 and PCP was calculated and the results indicated that the reaction between PCP and permanganate is relatively fast with a second order rate k"∼ 30 M(-1)s(-1)...
March 18, 2017: Environmental Technology
https://www.readbyqxmd.com/read/28314239/likelihood-ratio-and-posterior-odds-in-forensic-genetics-two-sides-of-the-same-coin
#12
Amke Caliebe, Susan Walsh, Fan Liu, Manfred Kayser, Michael Krawczak
It has become widely accepted in forensics that, owing to a lack of sensible priors, the evidential value of matching DNA profiles in trace donor identification or kinship analysis is most sensibly communicated in the form of a likelihood ratio (LR). This restraint does not abate the fact that the posterior odds (PO) would be the preferred basis for returning a verdict. A completely different situation holds for Forensic DNA Phenotyping (FDP), which is aimed at predicting externally visible characteristics (EVCs) of a trace donor from DNA left behind at the crime scene...
March 6, 2017: Forensic Science International. Genetics
https://www.readbyqxmd.com/read/28314210/options-and-limitations-for-bromate-control-during-ozonation-of-wastewater
#13
Fabian Soltermann, Christian Abegglen, Manfred Tschui, Sandro Stahel, Urs von Gunten
Wastewater treatment plants (WWTPs) are important point sources for micropollutants, which are harmful to freshwater organisms. Ozonation of wastewater is a powerful option to abate micropollutants, but may result in the formation of the potentially toxic oxidation by-product bromate in bromide-containing wastewaters. This study investigates options to reduce bromate formation during wastewater ozonation by (i) reducing the bromide concentration of the wastewater, (ii) lowering the ozone dose during wastewater treatment and (iii) adding hydrogen peroxide to limit the lifetime of ozone and quench the intermediates of the bromate formation pathway...
February 14, 2017: Water Research
https://www.readbyqxmd.com/read/28294331/context-dependent-extinction-of-an-appetitive-operant-conditioned-response-in-infant-rats
#14
Estefanía Orellana Barrera, Carlos Arias, Felisa González, Paula Abate
The present study evaluated context-dependent learning under an operant conditioning procedure in infant rats. Preweanling rats were trained in context A during postnatal days (PDs) 16 and 17 to learn an appetitive operant conditioning task, employing milk chocolate as appetitive reinforcer. On PD18 the operant response was extinguished in context A, or in an alternative context B. The change from context A to B between acquisition and extinction did not affect the number of responses during extinction, but slightly modified the shape of the extinction curve...
March 13, 2017: Developmental Psychobiology
https://www.readbyqxmd.com/read/28293159/intensified-tuberculosis-case-finding-implementation-of-isoniazid-preventive-therapy-and-associated-factors-among-people-living-with-human-immunodeficiency-virus-at-public-health-facilities-of-harari-region-eastern-ethiopia-a-cross-sectional-study
#15
Ayele Geleto, Degu Abate, Gudina Egata
OBJECTIVE: Globally, the number of people living with human immunodeficiency virus (PLHIV) particularly in sub-Saharan Africa is growing. This has been resulted in increased number of tuberculosis (TB) new cases. To control burden of TB among PLHIV, a number of collaborative TB/HIV activities were recommended. However, data about collaborative TB/HIV services in the study area is scarce. The objective of this study is to assess intensified TB case finding, implementation of isoniazid preventive therapy (IPT) and associated factors among PLHIV...
January 2017: International Journal of Health Sciences
https://www.readbyqxmd.com/read/28292609/organic-micropollutants-omps-oxidation-by-ozone-effect-of-activated-carbon-on-toxicity-abatement
#16
Oscar Rozas, Carolina Baeza, Katherine Núñez, Alfred Rossner, Roberto Urrutia, Héctor D Mansilla
Oxidation and removal of organic micropollutants (OMPs) on ultrapure (UPW) and natural water (NW) by ozone (O3) and ozone/powdered activated carbon (O3/PAC) have been studied. The OMPs atrazine (ATZ, herbicide), carbamazepine (CBZ, anticonvulsant), diclofenac (DCL, anti-inflammatory) and triclosan (TCS, antimicrobial) are incorporated continuously and uncontrolled on water treatment systems (e.g., drinking water treatment plants, wastewater treatment plants). Batch experiments on ultrapure and natural water showed that ATZ treated with O3 and O3/PAC has the slowest transformation rate (>90% at 30min reaction) while CBZ, DCL and TCS were oxidized very fast (>90% at ~5min)...
March 12, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28291206/-potential-for-use-of-hydroxypropyl-guar-in-tear-substitute-therapy
#17
V V Brzhesky, S Yu Golubev
Of the large number of polymers used in artificial tear formulations, natural polysaccharides - hydroxypropyl guar, sodium hyaluronate, chondroitin sulfate, dextran, etc., are gaining more and more popularity. Hydroxypropyl guar stands out through its ability to form a long-lasting structured matrix adhered to the damaged ocular surface and ensuring good wettability of the latter and regeneration of epithelial cells. At that, the viscosity of hydroxypropyl guar increases with increasing tear pH (which, in turn, correlates with the severity of xerosis) and further prolongs the moisturizing effect...
2017: Vestnik Oftalmologii
https://www.readbyqxmd.com/read/28290550/abseq-ultrahigh-throughput-single-cell-protein-profiling-with-droplet-microfluidic-barcoding
#18
Payam Shahi, Samuel C Kim, John R Haliburton, Zev J Gartner, Adam R Abate
Proteins are the primary effectors of cellular function, including cellular metabolism, structural dynamics, and information processing. However, quantitative characterization of proteins at the single-cell level is challenging due to the tiny amount of protein available. Here, we present Abseq, a method to detect and quantitate proteins in single cells at ultrahigh throughput. Like flow and mass cytometry, Abseq uses specific antibodies to detect epitopes of interest; however, unlike these methods, antibodies are labeled with sequence tags that can be read out with microfluidic barcoding and DNA sequencing...
March 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28288789/blood-loss-at-the-time-of-surgical-abortion-up-to-14weeks-in-anticoagulated-patients-a-case-series
#19
Bliss Kaneshiro, Mary Tschann, Jeffrey Jensen, Paula Bednarek, Ronnie Texeira, Alison Edelman
OBJECTIVE: To describe estimated blood loss (EBL) with surgical abortion≤14weeks gestation in anticoagulated patients. STUDY DESIGN: We invited 170 clinicians involved in a professional listserv to report cases when they performed a surgical abortion on a patient≤14weeks gestation taking an anticoagulant. Clinicians reported estimated blood loss (EBL) and bleeding-related complications (need for a blood transfusion, additional surgical procedures to treat bleeding)...
March 10, 2017: Contraception
https://www.readbyqxmd.com/read/28288359/efficacy-of-wood-charcoal-and-its-modified-form-as-packing-media-for-biofiltration-of-isoprene
#20
Navnita Srivastva, Ram S Singh, Suresh K Dubey
The efficacy of wood charcoal (WC) and nutrient-enriched wood charcoal (NWC) as biofilter packing media were assessed for isoprene biodegradation in a bioreactor comprising bioscrubber and a biofilter connected in series and inoculated with Pseudomonas sp. The bioreactors using WC and NWC exhibited >90% removal efficiency and around 369 g m(-3) h(-1) elimination capacity at around 404 g m(-3) h(-1) inlet loading rate. In both the bioreactors, the biofilter component showed better degradation capacity compared to the bioscrubber unit...
March 10, 2017: Journal of Environmental Management
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