C I Ma, J A Tirtorahardjo, S S Schweizer, J Zhang, Z Fang, L Xing, M Xu, D A Herman, M T Kleinman, B S McCullough, A M Barrios, R M Andrade
Toxoplasmosis, caused by Toxoplasma gondii , is a devastating disease affecting the brain and the eyes, frequently affecting immunocompromised individuals. Approximately 60 million people in the United States are already infected with T. gondii , representing a population at-risk of developing toxoplasmosis. Recent advances in treating cancer, autoimmune diseases, and organ transplants have contributed to this at-risk population's exponential growth. Paradoxically, treatments for toxoplasmosis have remained the same for more than 60 years, relying on medications well-known for their bone marrow toxicity and allergic reactions...
January 11, 2024: Microbiology Spectrum