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https://www.readbyqxmd.com/read/28820371/serologic-evidence-for-influenza-c-and-d-virus-among-ruminants-and-camelids-africa-1991-2015
#1
Elias Salem, Elizabeth A J Cook, Hicham Ait Lbacha, Justine Oliva, Félix Awoume, Gilbert L Aplogan, Emmanuel Couacy Hymann, Dishon Muloi, Sharon L Deem, Said Alali, Zaid Zouagui, Eric M Fèvre, Gilles Meyer, Mariette F Ducatez
Influenza D virus has been identified in America, Europe, and Asia. We detected influenza D virus antibodies in cattle and small ruminants from North (Morocco) and West (Togo and Benin) Africa. Dromedary camels in Kenya harbored influenza C or D virus antibodies, indicating a potential new host for these viruses.
September 2017: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/28813542/the-african-cholera-surveillance-network-africhol-consortium-meeting-10-11-june-2015-lom%C3%A3-togo
#2
Aline Munier, Berthe-Marie Njanpop-Lafourcade, Delphine Sauvageot, Raymond B Mhlanga, Léonard Heyerdahl, Johara Nadri, Richard Wood, Issaka Ouedraogo, Alexandre Blake, Laurent Akilimali Mukelenge, Jean-Claude B Anné, Abiba Banla Kere, Lucienne Dempouo, Sakoba Keita, José P M Langa, Issa Makumbi, Elibariki R Mwakapeje, Ian J Njeru, Olubunmi E Ojo, Isaac Phiri, Lorenzo Pezzoli, Bradford D Gessner, Martin Mengel
The fifth annual meeting of the African cholera surveillance network (Africhol) took place on 10-11 June 2015 in Lomé, Togo. Together with international partners, representatives from the 11 member countries -Cameroon, Côte d'Ivoire, Democratic Republic of Congo, Guinea, Kenya, Mozambique, Nigeria, Tanzania, Togo, Uganda, Zimbabwe- and an invited country (Malawi) shared their experience. The meeting featured three sessions: i) cholera surveillance, prevention and control in participating countries, ii) cholera surveillance methodology, such as cholera mapping, cost-effectiveness studies and the issue of overlapping epidemics from different diseases, iii) cholera laboratory diagnostics tools and capacity building...
2017: BMC Proceedings
https://www.readbyqxmd.com/read/28804654/histoplasmosis-by-histoplasma-capsulatum-var-duboisii-observed-at-the-laboratory-of-pathological-anatomy-of-lom%C3%A3-in-togo
#3
Tchin Darré, Bayaki Saka, Abas Mouhari-Touré, Améyo Monique Dorkenoo, Koffi Amégbor, Vincent Palokinam Pitche, Gado Napo-Koura
Our study aimed to describe the epidemiological, clinical, and diagnostic aspects of African histoplasmosis in Togo through a descriptive and cross-sectional study on histological diagnosed African histoplasmosis in Pathology Department of Lomé from 2002 to 2016 (15 years). A total of 17 cases of African histoplasmosis were diagnosed. The sex ratio (M/F) was 1.8. The annual incidence was 1.1 cases. The mean age of the patients was 27.2 ± 0.4 years. All our patients were of social categories with a low socioeconomic level...
2017: Journal of Pathogens
https://www.readbyqxmd.com/read/28802687/-oct-topographic-characteristics-of-the-optic-nerve-in-patients-clinically-suspected-to-have-large-optic-disc-cupping-in-togo
#4
N Maneh, K D Ayena, K Vonor, K B Nonon Saa, K M Amedome, K B Dzidzinyo, C B Ikessieba, K R Kuaovi, M Banla, K P Balo
PURPOSE: To describe topographic characteristics of optic discs clinically suspected of large cupping. MATERIALS AND METHODS: This is retrospective study conducted from the January 2 to December 31 on the OCT registry and data base of a private ophthalmologic center in Lomé (Togo). We included records of patients with large cupping - CDR (cup-to-disc ratio) ≥ 0.4 -clinically observed and having undergone OCT-optic disc analysis. RESULTS: Three hundred and thirty-five patients (619 eyes) were studied, with a mean age of 41...
August 9, 2017: Journal Français D'ophtalmologie
https://www.readbyqxmd.com/read/28761614/-impact-of-controlled-temperature-chain-ctc-approach-on-immunization-coverage-achieved-during-the-preventive-vaccination-campaign-against-meningitis-a-using-menafrivac-in-togo-in-2014
#5
Dadja Essoya Landoh, Anna-Léa Kahn, Anani Lacle, Kodjovi Adjeoda, Bayaki Saka, Issifou Yaya, Danladi Ibrahim Nassoury, Assima Kalao, Makawa-Sy Makawa, Nsiari-Mueyi Joseph Biey, Andre Bita, Yaovi Temfa Toke, Petit Dörte, Lucile Imboua, Olivier Ronveaux
METHOD: We conducted a survey from 9 to 14 March 2015 (for approximately 3 months) after the end of the vaccination campaign in these four regions. Interviewees were selected using two stages cluster sampling stratified according to the regions. MenAfriVac vaccine in Controlled Temperature Chain (CTC) was used in 10 districts, in Togo. RESULTS: A total of 2707 households were surveyed and 9082 people aged 1-29 years were interviewed. The average age of the individuals surveyed was 11...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28746856/biphasic-effect-of-profilin-impacts-the-formin-mdia1-force-sensing-mechanism-in-actin-polymerization
#6
Hiroaki Kubota, Makito Miyazaki, Taisaku Ogawa, Togo Shimozawa, Kazuhiko Kinosita, Shin'ichi Ishiwata
Formins are force-sensing proteins that regulate actin polymerization dynamics. Here, we applied stretching tension to individual actin filaments under the regulation of formin mDia1 to investigate the mechanical responses in actin polymerization dynamics. We found that the elongation of an actin filament was accelerated to a greater degree by stretching tension for ADP-G-actin than that for ATP-G-actin. An apparent decrease in the critical concentration of G-actin was observed, especially in ADP-G-actin. These results on two types of G-actin were reproduced by a simple kinetic model, assuming the rapid equilibrium between pre- and posttranslocated states of the formin homology domain two dimer...
July 25, 2017: Biophysical Journal
https://www.readbyqxmd.com/read/28738081/comparative-molecular-analyses-of-invasive-fall-armyworm-in-togo-reveal-strong-similarities-to-populations-from-the-eastern-united-states-and-the-greater-antilles
#7
Rodney N Nagoshi, Djima Koffi, Komi Agboka, Kodjo Agbeko Tounou, Rahul Banerjee, Juan Luis Jurat-Fuentes, Robert L Meagher
The fall armyworm (Spodoptera frugiperda, J.E. Smith) is a noctuid moth that is a major and ubiquitous agricultural pest in the Western Hemisphere. Infestations have recently been identified in several locations in Africa, indicating its establishment in the Eastern Hemisphere where it poses an immediate and significant economic threat. Genetic methods were used to characterize noctuid specimens infesting multiple cornfields in the African nation of Togo that were tentatively identified as fall armyworm by morphological criteria...
2017: PloS One
https://www.readbyqxmd.com/read/28718287/preparation-of-3-iodoquinolines-from-n-tosyl-2-propynylamines-with-diaryliodonium-triflate-and-n-iodosuccinimide
#8
Teppei Sasaki, Katsuhiko Moriyama, Hideo Togo
4-Aryl- and 4-alkyl substituted 3-iodoquinolines could be smoothly obtained in one pot by treating N-tosyl-2-propynylamines with diaryliodonium triflate in the presence of K3PO4 and a catalytic amount of CuCl at room temperature, followed by treatment with N-iodosuccinimide and BF3•OEt2 at 0 °C, and then NaOH in methanol solution. The product, 3-iodo-4-phenylquinoline was smoothly transformed into 4-phenylquinoline with zinc; 4-phenyl-3-toluenesulfenylquinoline with toluenethiol, K2CO3, and CuI; 4-phenyl-3-phenylethynylquinoline with the Sonogashira coupling reaction; 4-phenyl-3-styrylquinoline with the Heck coupling reaction; 3,4-diphenylquinoline with the Suzuki-Miyaura coupling reaction; 2-cyclohexyl-3-iodo-4-phenylquinoline with cyclohexanecarboxylic acid, Ag2CO3, and K2S2O8; and 3-iodo-2-(2',5'-dioxan-1'-yl)-4-phenylquinoline with benzoyl peroxide in 1,4-dioxane...
July 18, 2017: Journal of Organic Chemistry
https://www.readbyqxmd.com/read/28717698/neuroblastoma-in-africa-a-survey-by-the-franco-african-pediatric-oncology-group
#9
Fousseyni Traoré, Francis Eshun, Boubacar Togo, Jean Jacques Atteby Yao, Mbuli Robert Lukamba
PURPOSE: Neuroblastoma is a sympathoadrenal lineage neural crest-derived tumor. It is the third most common childhood malignancy in the Western world. Studies from the United States show that black patients with neuroblastoma have a greater proportion of high-risk neuroblastoma with poorer prognosis compared with white patients. In Africa, there are few published data on the epidemiology and management of neuroblastoma. The primary aim of this study was to assess the diagnostic and therapeutic resources available for the management of neuroblastoma within the Franco-African Pediatric Oncology Group (GFAOP)...
August 2016: Journal of Global Oncology
https://www.readbyqxmd.com/read/28713359/exploring-the-diversity-of-field-strains-of-brucella-abortus-biovar-3-isolated-in-west-africa
#10
Moussa Sanogo, David Fretin, Eric Thys, Claude Saegerman
Brucellosis is one of the most widespread bacterial zoonotic diseases in the world, affecting both humans and domestic and wild animals. Identification and biotyping of field strains of Brucella are of key importance for a better knowledge of the epidemiology of brucellosis, for identifying appropriate antigens, for managing disease outbreaks and for setting up efficient preventive and control programmes. Such data are required both at national and regional level to assess potential threats for public health...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28706850/pneumothorax-caused-by-cystic-and-nodular-lung-metastases-from-a-malignant-uterine-perivascular-epithelioid-cell-tumor-pecoma
#11
Shouichi Okamoto, Moegi Komura, Yasuhisa Terao, Aiko Kurisaki-Arakawa, Takuo Hayashi, Tsuyoshi Saito, Shinsaku Togo, Akira Shiokawa, Keiko Mitani, Etsuko Kobayashi, Toshio Kumasaka, Kazuhisa Takahashi, Kuniaki Seyama
Perivascular epithelioid cell tumors (PEComas) are mesenchymal neoplasms with immunoreactivity for both melanocytic and smooth muscle markers. PEComas occur at multiple sites, and malignant PEComas can undergo metastasis, recurrence and aggressive clinical courses. Although the lung is a common metastatic site of PEComas, they usually appear as multiple nodules but rarely become cystic or cavitary. Here, we describe a female patient whose lungs manifested multiple cystic, cavity-like and nodular metastases 3 years after the resection of uterine tumors tentatively diagnosed as epithelioid smooth muscle tumors with uncertain malignant potential...
2017: Respiratory Medicine Case Reports
https://www.readbyqxmd.com/read/28699235/expression-patterns-of-claudins-in-patients-with-triple-negative-breast-cancer-are-associated-with-nodal-metastasis-and-worse-outcome
#12
Ayaka Katayama, Tadashi Handa, Kei Komatsu, Maria Togo, Jun Horiguchi, Masahiko Nishiyama, Tetsunari Oyama
Claudins (CLDNs) are key cell adhesion molecules, which compose tight junctions (TJs), and the disruption of TJs is associated with cancer development. Here we immunohistochemically studied expression patterns of CLDNs in 222 primary invasive breast cancers including 68 triple-negative breast cancers (TNBCs), and examined their correlation with epithelial-to-mesenchymal transition (EMT)-related markers, breast cancer stem cell (BCSC) markers, and clinicopathological features including patients' clinical outcome...
July 11, 2017: Pathology International
https://www.readbyqxmd.com/read/28660604/-hiv-prevalence-and-behavioral-studies-among-female-sex-workers-in-togo-in-2015
#13
J N Teclessou, S Akakpo, D Gbetoglo, G Koumagnanou, A Singo, P Pitché
The purpose of this study is to determine the seroprevalence of HIVamong female sex workers (FSWs) and to document the behavior in this target population four years after the last study and possibly readjust these interventions. We conducted from March 27 to April 4, 2015 a crosssectional study of 1197 FSWs. Behavior data were collected by interviewer-administered questionnaires. The FSWs were then subjected to blood tests to measure the prevalence of HIV. The average age of respondents FSWs was 28 years and 20% had their first sexual intercourse before 15 years old...
June 28, 2017: Bulletin de la Société de Pathologie Exotique
https://www.readbyqxmd.com/read/28642581/molecular-methods-to-detect-spodoptera-frugiperda-in-ghana-and-implications-for-monitoring-the-spread-of-invasive-species-in-developing-countries
#14
Matthew J W Cock, Patrick K Beseh, Alan G Buddie, Giovanni Cafá, Jayne Crozier
Spodoptera frugiperda (J. E. Smith) (Lepidoptera: Noctuidae) is a polyphagous pest indigenous throughout the Americas, which recently appeared in Africa, first reported from São Tomé, Nigeria, Bénin and Togo in 2016, and which we now report from Ghana. This species is recognised to comprise two morphologically identical but genetically distinct strains or species in the Americas, and we found both to be present in Ghana. We discuss possible routes of entry to Africa, of which the likeliest is adults and/or egg masses transported on direct commercial flights between the Americas and West Africa, followed by dispersal by adult flight within Africa...
June 22, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28641892/fighting-fake-medicines-first-quality-evaluation-of-cardiac-drugs-in-africa
#15
Marie Antignac, Bara Ibrahima Diop, Diane Macquart de Terline, Melisande Bernard, Bernard Do, Stéphane Méo Ikama, Roland N'Guetta, Dadhi M Balde, Yessoufou Tchabi, Abdallahi Sidi Aly, Ibrahim Ali Toure, Patrick Zabsonre, Jean Marie F Damorou, Jean Laurent Takombe, Christine Fernandez, Muriel Tafflet, Jean Philippe Empana, Pierre François Plouin, Kumar Narayanan, Eloi Marijon, Xavier Jouven
BACKGROUND: The growing menace of poor quality and falsified drugs constitutes a major hazard, compromising healthcare and patient outcomes. Efforts to assess drug standards worldwide have almost exclusively focused on anti-microbial drugs; with no study to date on cardiovascular drugs. Our study aims to assess quality of seven routinely used cardiovascular medications (anticoagulants, antihypertensives and statins) in ten Sub-Saharan African countries. METHODS: Drugs were prospectively collected using standardized methods between 2012 and 2014 from licensed (random pharmacies) and unlicensed (street-markets) places of sale in Africa...
September 15, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28603828/profile-of-bone-malignancy-among-rheumatology-inpatients-in-lom%C3%A3-togo
#16
Kodjo Kakpovi, Owonayo Oniankitan, Messanvi Kpoti, Prénam Houzou, Viwalé Es Koffi-Tessio, Komi C Tagbor, Eyram Fianyo, Moustafa Mijiyawa
BACKGROUND: The incidence of bone malignancy in adulthood seems poorly known in Black Africa. AIM: To determine the epidemiological, clinical, and paraclinical profile of bone malignancy in patients admitted to the Rheumatology Department in Lomé (Togo). METHODS: A retrospective study was conducted over 19 years on records of hospital patients admitted for bone malignancy. RESULTS: One hundred sixty-six of 2018 (8.2%) patients (98 men and 68 women) admitted suffered from bone malignancy...
August 2016: La Tunisie Médicale
https://www.readbyqxmd.com/read/28602653/infrasonic-and-ultrasonic-hearing-evolved-after-the-emergence-of-modern-whales
#17
Mickaël J Mourlam, Maeva J Orliac
Mysticeti (baleen whales) and Odontoceti (toothed whales) today greatly differ in their hearing abilities: Mysticeti are presumed to be sensitive to infrasonic noises [1-3], whereas Odontoceti are sensitive to ultrasonic sounds [4-6]. Two competing hypotheses exist regarding the attainment of hearing abilities in modern whales: ancestral low-frequency sensitivity [7-13] or ancestral high-frequency sensitivity [14, 15]. The significance of these evolutionary scenarios is limited by the undersampling of both early-diverging cetaceans (archaeocetes) and terrestrial hoofed relatives of cetaceans (non-cetacean artiodactyls)...
June 19, 2017: Current Biology: CB
https://www.readbyqxmd.com/read/28602443/-benign-neonatal-hemangiomatosis-an-observation-in-a-child-in-togo
#18
G Mahamadou, B Saka, A Mouhari-Toure, M Tchaou, S Pessinaba, W Gnassingbé, K Kombaté, P Pitché
No abstract text is available yet for this article.
June 8, 2017: Annales de Dermatologie et de Vénéréologie
https://www.readbyqxmd.com/read/28592935/surgery-on-burns-sequelae-in-developing-countries
#19
O El Ezzi, M Dolci, C Dufour, R Bossou, A de Buys Roessingh
The purpose of this study is to analyze the effectiveness of surgery and follow-up of children operated on for burn sequelae. For many years, we have organized two missions per year to Benin and Togo, one for surgery and one for follow-up. We analyzed the files of children born in Africa and victims of burns from the years 2002 to 2011. Children were referred through a non-governmental organization (NGO) and assessed in Africa by local paediatricians before and after surgery. Treatment consisted in operating on burn sequelae such as contractures, hypertrophic scars and hard cords...
March 31, 2017: Annals of Burns and Fire Disasters
https://www.readbyqxmd.com/read/28589394/single-and-chronic-l-serine-treatments-exert-antidepressant-like-effects-in-rats-possibly-by-different-means
#20
Mao Nagasawa, Tsuyoshi Otsuka, Yuki Togo, Masakazu Yamanaga, Junki Yoshida, Nobuo Uotsu, Sachiyuki Teramoto, Shinobu Yasuo, Mitsuhiro Furuse
In the present study, the effects of both single (6 mmol L-serine/10 ml/kg orally administrated) and chronic (2% L-serine solution freely given for 28 days) treatments on depression-like behavior were evaluated in Wistar rats, representing the control, and Wistar Kyoto rats, representing an animal model of depression. Both single and chronic L-serine treatments decreased the duration of immobility, which is an index of a depressive-like state, in the forced swimming test in both strains. However, the decreases in the duration of immobility appear to be regulated differently by the different mechanisms involved in single and chronic L-serine treatments...
June 6, 2017: Amino Acids
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