keyword
MENU ▼
Read by QxMD icon Read
search

Low resource setting

keyword
https://www.readbyqxmd.com/read/29772094/quantifying-biomolecular-binding-constants-using-video-paper-analytical-devices
#1
Benjamin S Miller, Claudio Parolo, Valerian Turbé, Candice E Keane, Eleanor R Gray, Rachel McKendry
We report a novel ultralow-cost biochemical analysis platform to quantify protein dissociation binding constants and kinetics using paper microfluidics. Our approach marries video imaging with one of humankind's oldest materials - paper, requiring no large, expensive laboratory equipment, complex microfluidics or external power. Temporal measurements of nanoparticle-antibody conjugates binding on paper is found to follow the Langmuir Adsorption Model. This is exploited to measure a series of antibody-antigen dissociation constants on paper, showing excellent agreement with a gold-standard benchtop interferometer...
May 17, 2018: Chemistry: a European Journal
https://www.readbyqxmd.com/read/29771949/correlates-of-domestic-violence-perpetration-reporting-among-recently-married-men-residing-in-slums-in-pune-india
#2
Ameeta S Kalokhe, Sandhya R Iyer, Keshav Gadhe, Tuman Katendra, Anuradha Paranjape, Carlos Del Rio, Rob Stephenson, Seema Sahay
Domestic violence (DV) is prevalent in low-income and slum-dwelling communities in India. To date, the focus of DV prevention in resource-poor settings has largely been with women. We herein aim to identify correlates of DV perpetration to help inform future primary prevention efforts that focus on behavioral change in men. Utilizing a cross-sectional design, potential correlates of DV perpetration were explored among a geographically-clustered random sample of 100 recently-married men residing in slums in Pune, India...
2018: PloS One
https://www.readbyqxmd.com/read/29771555/the-quality-of-assessments-for-childhood-psychopathology-within-a-regional-medical-center
#3
Adam F Sattler, Jarrod M Leffler, Nicole L Harrison, Ewa D Bieber, Joseph J Kosmach, Leslie A Sim, Stephen P H Whiteside
Accurate assessment is essential to implementing effective mental health treatment; however, little research has explored child clinicians' assessment practices in applied settings. The current study thus examines practitioners' use of evidence-based assessment (EBA) instruments (i.e., self-report measures and structured interviews), specificity of identified diagnoses (i.e., use of specific diagnostic labels vs. nonstandardized labels, not otherwise specified [NOS] diagnoses, and adjustment disorder diagnoses), and documentation of Diagnostic and Statistical Manual of Mental Disorders (4th ed...
May 17, 2018: Psychological Services
https://www.readbyqxmd.com/read/29771453/functionalization-of-lipid-based-nutrient-supplement-with-%C3%AE-cyclodextrin-inclusions-of-oregano-essential-oil
#4
Shashank Gaur, Emely C Lopez, Ankur Ojha, Juan E Andrade
Intestinal parasitic infection is one of the main causes of acute undernutrition in children. Oral consumption of oregano essential oil (OEO) can reduce intestinal parasitic infections, however, its addition to therapeutic and supplementary foods is hampered by its undesirable flavor. The objective of this study was to develop a functional lipid-based nutrient supplement (LNS) containing OEO, which is stable, acceptable and provides targeted intestinal delivery of bioactive. β-cyclodextrin (β-CyD) inclusion complexes of OEO (β-CyD-OEO), and carvacrol (β-CyD-CV) (1:1 molar) were prepared using slurry complexation (-20 °C) method and characterized based on encapsulation efficiency, moisture content, morphology, and 2-phase in vitro digestion stability...
May 17, 2018: Journal of Food Science
https://www.readbyqxmd.com/read/29770625/risks-of-cervical-intraepithelial-neoplasia-grade-3-or-invasive-cancers-in-ascus-women-with-different-management-a-population-based-cohort-study
#5
Yi Jou Tai, Yun Yuan Chen, Huang Cheng Hsu, Chun Ju Chiang, San Lin You, Chi An Chen, Wen Fang Cheng
OBJECTIVE: To investigate the progression risk of atypical squamous cells of undetermined significance (ASCUS) with different clinical managements. METHODS: Women with their first diagnosis of ASCUS cytology were retrieved from the national cervical cancer screening database and linked to the national health insurance research database to identify the management of these women. The incidences of developing cervical intraepithelial neoplasia grade 3 and invasive cervical cancer (CIN3+) were calculated, and the hazard ratios (HRs) were estimated using a Cox proportional hazards model...
March 20, 2018: Journal of Gynecologic Oncology
https://www.readbyqxmd.com/read/29770210/identification-of-publicly-available-data-sources-to-inform-the-conduct-of-health-technology-assessment-in-india
#6
Laura Downey, Neethi Rao, Lorna Guinness, Miqdad Asaria, Shankar Prinja, Anju Sinha, Rajni Kant, Arvind Pandey, Francoise Cluzeau, Kalipso Chalkidou
Background: Health technology assessment (HTA) provides a globally-accepted and structured approach to synthesising evidence for cost and clinical effectiveness alongside ethical and equity considerations to inform evidence-based priorities. India is one of the most recent countries to formally commit to institutionalising HTA as an integral component of the heath resource allocation decision-making process. The effective conduct of HTA depends on the availability of reliable data.   Methods : We draw from our experience of collecting, synthesizing, and analysing health-related datasets in India and internationally, to highlight the complex requirements for undertaking HTA, and explore the availability of such data in India...
2018: F1000Research
https://www.readbyqxmd.com/read/29769384/meta-research-on-oncology-trials-a-toolkit-for-researchers-with-limited-resources
#7
Rachel P Riechelmann, Julien Péron, Bostjan Seruga, Everardo D Saad
"Meta-research" is a discipline that investigates research practices. Meta-research on clinical trials is an attempt to summarize descriptive and methodological features of published or ongoing clinical trials, including aspects of their implementation, design, analysis, reporting, and interpretation. In this type of investigation, the unit of analysis is a primary source of information about a clinical trial (e.g., published reports, study protocols, or abstracts), with meta-research being a second layer of information that summarizes what is known from various primary sources...
May 16, 2018: Oncologist
https://www.readbyqxmd.com/read/29769263/how-i-treat-burkitt-lymphoma-in-children-adolescents-and-young-adults-in-sub-saharan-africa
#8
Satish Gopal, Thomas G Gross
Burkitt lymphoma (BL) is the most common pediatric cancer in sub-Saharan Africa (SSA), and also occurs frequently among adolescents and young adults (AYA), often associated with human immunodeficiency virus (HIV). Treating BL in SSA poses particular challenges. Although highly effective, high-intensity cytotoxic treatments used in resource-rich settings are usually not feasible, and lower-intensity continuous infusion approaches are impractical. In this paper, based on evidence from the region, we review management strategies for SSA focused on diagnosis, use of pre-phase, and definitive treatment...
May 16, 2018: Blood
https://www.readbyqxmd.com/read/29769056/report-on-an-international-workshop-on-kangaroo-mother-care-lessons-learned-and-a-vision-for-the-future
#9
Adriano Cattaneo, Adidja Amani, Nathalie Charpak, Socorro De Leon-Mendoza, Sarah Moxon, Somashekhar Nimbalkar, Giorgio Tamburlini, Julieta Villegas, Anne-Marie Bergh
BACKGROUND: Globally, complications of prematurity are the leading cause of death in children under five. Preterm infants who survive their first month of life are at greater risk for various diseases and impairments in infancy, childhood and later life, representing a heavy social and economic burden for families, communities and health and social systems. Kangaroo mother care (KMC) is recommended as a beneficial and effective intervention for improving short- and long-term preterm birth outcomes in low- and high-income settings...
May 16, 2018: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29768264/opportunities-and-challenges-in-global-perinatal-research
#10
Jessica Duby, Renee Sharma, Zulfiqar A Bhutta
BACKGROUND: The global plight of stillbirths and neonatal mortality is concentrated in low- and middle-income countries. The ambitious targets introduced by the World Health Organization in the Every Newborn Action Plan demand a commitment to research that promotes equitable perinatal outcomes. OBJECTIVES: The aim of this review was to understand the opportunities for global perinatal research and the accompanying challenges. METHODS: We conducted a literature search to identify research prioritization exercises from 2014 to 2018 pertaining to global perinatal health...
May 16, 2018: Neonatology
https://www.readbyqxmd.com/read/29768107/does-expanding-fiscal-space-lead-to-improved-funding-of-the-health-sector-in-developing-countries-lessons-from-kenya-lagos-state-nigeria-and-south-africa
#11
Jane Doherty, Doris Kirigia, Chijioke Okoli, Jane Chuma, N Ezumah, Hyacinth Ichoku, Kara Hanson, Diane McIntyre
BACKGROUND: The global focus on promoting Universal Health Coverage has drawn attention to the need to increase public domestic funding for health care in low- and middle-income countries. OBJECTIVES: This article examines whether increased tax revenue in the three territories of Kenya, Lagos State (Nigeria) and South Africa was accompanied by improved resource allocation to their public health sectors, and explores the reasons underlying the observed trends. METHODS: Three case studies were conducted by different research teams using a common mixed methods approach...
2018: Global Health Action
https://www.readbyqxmd.com/read/29767678/identification-of-etiology-specific-diarrhea-associated-with-linear-growth-faltering-in-bangladeshi-infants
#12
Amanda E Schnee, Rashidul Haque, Mami Taniuchi, Jashim Uddin, Masud Alam, Jie Liu, Elizabeth T Rogawski, Beth Kirkpatrick, Eric R Houpt, William A Petri, James A Platts-Mills
Childhood diarrhea in low-resource settings has been variably linked to linear growth shortfalls. However, the association between etiology-specific diarrhea and growth has not been comprehensively evaluated. We tested diarrheal stools collected from the Performance of Rotavirus and Oral Polio Vaccines in Developing Countries study from 2011-2013 in Dhaka, Bangladesh by quantitative polymerase chain reaction for a broad range of enteropathogens to characterize diarrhea etiology and examine the association between etiology-specific diarrhea and linear growth and systemic inflammation...
May 15, 2018: American Journal of Epidemiology
https://www.readbyqxmd.com/read/29765241/prevalence-of-antibiotic-prescription-in-southern-italian-outpatients-real-world-data-analysis-of-socioeconomic-and-sociodemographic-variables-at-a-municipality-level
#13
Veronica Russo, Valeria Marina Monetti, Francesca Guerriero, Ugo Trama, Antonella Guida, Enrica Menditto, Valentina Orlando
Purpose: The aim of this study was to analyze the geographic variation in systemic antibiotic prescription at a regional level and to explore the influence of socioeconomic and sociodemographic variables. Methods: This study was a retrospective analysis of reimbursement pharmacy records in the outpatient settings of Italy's Campania Region in 2016. Standardized antibiotic prescription rates were calculated at municipality and Local Health Unit (LHU) level. Antibiotic consumption was analyzed as defined daily doses (DDD)/1000 inhabitants per day (DID)...
2018: ClinicoEconomics and Outcomes Research: CEOR
https://www.readbyqxmd.com/read/29764824/achieving-full-neurological-recovery-in-snakebite-using-best-supportive-care
#14
Sally Wright, Genevieve Haddock
A 29-year-old woman presented to a community hospital in Sierra Leone 2 hours after being bitten by an unknown snake. On arrival, she was agitated though alert, however deteriorated into respiratory arrest. There was no local availability of antivenom. The patient remained in respiratory arrest undergoing best supportive care in a low-resource setting for 2 hours 55 minutes before returning to spontaneous ventilation. She went on to make a full neurological recovery. Though spontaneous recovery following snakebite envenoming is rare, this case showcases that good communication and basic manoeuvres can have a hugely positive impact on patient outcome...
May 14, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29764384/caesarean-section-audit-to-improve-quality-of-care-in-a-rural-referral-hospital-in-tanzania
#15
Luuk Dekker, Tessa Houtzager, Omary Kilume, John Horogo, Jos van Roosmalen, Angelo Sadock Nyamtema
BACKGROUND: Caesarean section (CS) is often a life-saving procedure, but can also lead to serious complications, even more so in low-resource settings. Therefore unnecessary CS should be avoided and optimal circumstances for vaginal delivery should be created. In this study, we aim to audit indications for Caesarean sections and improve decision-making and obstetric management. METHODS: Audit of all cases of CS performed from January to August 2013 was performed in a rural referral hospital in Tanzania...
May 15, 2018: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29764103/unit-costing-of-health-extension-worker-activities-in-ethiopia-a-model-for-managers-at-the-district-and-health-facility-level
#16
Maureen E Canavan, Erika Linnander, Shirin Ahmed, Halima Mohammed, Elizabeth H Bradley
BACKGROUND: Over the last decade, Ethiopia has made impressive national improvements in health outcomes, including reductions in maternal, neonatal, infant, and child mortality attributed in large part to their Health Extension Program (HEP). As this program continues to evolve and improve, understanding the unit cost of health extension worker (HEW) services is fundamental to planning for future growth and ensuring adequate financial support to deliver effective primary care throughout the country...
September 2, 2017: International Journal of Health Policy and Management
https://www.readbyqxmd.com/read/29763458/immunity-levels-to-poliovirus-in-lao-children-and-adults-before-the-vaccine-derived-poliovirus-outbreak-a-retrospective-study
#17
Maude Pauly, Antony P Black, Phonepaseuth Khampanisong, Phonethipsavanh Nouanthong, Judith M Hübschen, Naphavanh Nanthavong, Kong Sayasinh, Prapan Jutavijittum, Bounthome Samountry, Anonh Xeuatvongsa, Sabine Diedrich, Claude P Muller
In 2015, several provinces in Lao People's Democratic Republic (Lao PDR) experienced a vaccine-derived poliovirus outbreak. This survey was conducted (i) to evaluate the vaccination coverage in different settings and cohorts using the seroprevalence of anti-poliovirus (PV) antibodies as a surrogate measure, and (ii) to explore the usefulness of an ELISA in a country with limited resources and a specific epidemiological setting. IgG antibodies were assessed by ELISA in Lao children (n = 1216) and adults (n = 1228), including blood donors and health care workers...
2018: PloS One
https://www.readbyqxmd.com/read/29762153/increased-mortality-and-reoperation-rates-after-treatment-for-septic-arthritis-of-the-knee-in-people-who-inject-drugs-nationwide-inpatient-sample-2000-2013
#18
David Hyung Won Oh, Alysse Gail Wurcel, David Joseph Tybor, Deirdre Burke, Mariano E Menendez, Matthew Joseph Salzler
BACKGROUND: The United States has a growing opioid epidemic impacting all aspects of health care including orthopaedic surgery. Septic arthritis of the knee is a condition commonly encountered by orthopaedic surgeons related to opioid and injection drug use (IDU). Changes in the frequency of hospitalizations for IDU-related septic arthritis and differences in septic arthritis patient outcomes according to IDU status in the setting of the burgeoning opioid epidemic are unknown. QUESTIONS/PURPOSES: (1) What proportion of patients with septic arthritis of the knee use injection drugs? (2) Are there any differences in complications, reoperations, length of stay, and leaving against medical advice among patients with septic arthritis of the knee with and without IDU? (3) What are the age and racial trends in IDU-related septic arthritis of the knee from 2000 to 2013? METHODS: The Healthcare Cost and Utilization Project, Nationwide Inpatient Sample database of years 2000 to 2013 was utilized for patients between ages 15 and 64 years with a principal discharge diagnosis of native septic arthritis of the lower leg, the vast majority of which represents the knee...
May 14, 2018: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/29761701/semi-quantitative-nucleic-acid-test-with-simultaneous-isotachophoretic-extraction-and-amplification
#19
Andrew T Bender, Mark D Borysiak, Amanda M Levenson, Lorraine Lillis, David S Boyle, Jonathan D Posner
Nucleic acid amplification tests (NAATs) provide high diagnostic accuracy for infectious diseases and quantitative results for monitoring viral infections. The majority of NAATs require complex equipment, cold chain dependent reagents, and skilled technicians to perform tests. This largely confines NAATs to centralized laboratories and can significantly delay appropriate patient care. Low-cost, point-of-care (POC) NAATs are especially needed in low-resource settings to provide patients with diagnosis and treatment planning in a single visit to improve patient care...
May 15, 2018: Analytical Chemistry
https://www.readbyqxmd.com/read/29760598/predictors-of-chemoradiation-related-febrile-neutropenia-prophylaxis-in-older-adults-experience-from-a-limited-resource-setting
#20
Aparna Gangopadhyay
Aim: To identify risk factors that lower efficacy of antibiotic prophylaxis of febrile neutropenia among older patients on chemoradiation. Background: Audit of institutional data showed that older adults are at higher risk of febrile neutropenia during chemoradiation. In limited resource settings widespread use of Granulocyte-Colony Stimulating Factor (G-CSF) is not economically feasible and antibiotics are used commonly. Despite compliance with antibiotics, prophylaxis is inadequate in many patients owing to patient and tumor related factors...
May 2018: Reports of Practical Oncology and Radiotherapy
keyword
keyword
29822
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"