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https://www.readbyqxmd.com/read/27903014/effects-of-meteorological-variables-on-the-incidence-of-rupture-of-intracranial-aneurysms-in-central-new-jersey
#1
Marissa Kellogg, Dimitriy Petrov, Nitin Agarwal, Nitesh V Patel, David Richard Hansberry, Prateek Agarwal, Michael Brimacombe, Chirag D Gandhi, Charles Prestigiacomo
Introduction Previous studies have suggested relationships between the rupture of intracranial aneurysms and meteorological variables such as season, barometric pressure, and temperature. Our objective was to examine the relationship between the incidence of hospital admissions secondary to aneurysmal subarachnoid hemorrhage (aSAH) and meteorological variables in central New Jersey. Methods The study population consisted of 312 patients who presented to University Hospital in Newark, New Jersey, between January 1, 2003, and December 31, 2008, with aSAH...
November 30, 2016: Journal of Neurological Surgery. Part A, Central European Neurosurgery
https://www.readbyqxmd.com/read/27890755/predictors-of-shunt-insertion-in-aneurysmal-subarachnoid-hemorrhage
#2
Rouzbeh Motiei-Langroudi, Nimer Adeeb, Paul M Foreman, Mark R Harrigan, Winfield S Fisher, Nilesh A Vyas, Robert H Lipsky, Beverly C Walters, Shane R Tubbs, Mohammadali M Shoja, Justin M Moore, Raghav Gupta, Christopher S Ogilvy, Ajith T Thomas, Christoph J Griessenauer
OBJECTS: Hydrocephalus is a common complication of aneurysmal subarachnoid hemorrhage (aSAH) requiring permanent cerebrospinal fluid (CSF) diversion in up to two thirds of patients. Factors that predict permanent CSF diversion are not well established. METHODS: An exploratory analysis of 149 patients enrolled in the Cerebral Aneurysm Renin Angiotensin System (CARAS) study was performed in an effort to identify factors predictive of permanent CSF diversion following aSAH; only the 135 patients surviving the initial hospitalization were included in the present study...
November 24, 2016: World Neurosurgery
https://www.readbyqxmd.com/read/27871451/aneurysm-rebleeding-after-poor-grade-aneurysmal-subarachnoid-hemorrhage-predictors-and-impact-on-clinical-outcomes
#3
Bing Zhao, Yilin Fan, Ye Xiong, Rong Yin, Kuang Zheng, Zequn Li, Xianxi Tan, Hua Yang, Ming Zhong
BACKGROUND: Aneurysm rebleeding is a major cause of morbidity and mortality after aneurysmal subarachnoid hemorrhage (aSAH) and more often occurs in patients with poor-grade aSAH. Limited data on predictors of rebleeding in these patients are available. OBJECTIVE: To investigate predictors of aneurysm rebleeding after poor-grade aSAH and the association of rebleeding with clinical outcomes. METHODS: A multicenter poor-grade aneurysm study was a prospective and observational registry of consecutive patients who presented with poor-grade aSAH defined as a World Federation of Neurosurgical Societies (WFNS) grade of IV or V...
December 15, 2016: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/27867126/coiling-is-not-superior-to-clipping-in-patients-with-high-grade-aneurysmal-subarachnoid-hemorrhage-a-systematic-review-and-meta-analysis
#4
REVIEW
Zhi-Wei Xia, Xiao-Ming Liu, Jun-Yu Wang, Hui Cao, Feng-Hua Chen, Jun Huang, Qi-Zhuang Li, Shuang-Shi Fan, Bing Jiang, Zi-Gui Chen, Quan Cheng
BACKGROUND: Outcomes of coiling embolization versus clipping for patients with high-grade aneurysmal subarachnoid hemorrhage (aSAH) have not been previously compared. We reviewed the current evidence regarding the safety and efficacy of clipping versus coiling for high-grade aSAH. METHODS: We conducted a meta-analysis of studies that comparring clipping with coiling in patients with high-grade aSAH published from January 1999-February 2016 in Medline, Embase, and Cochrane databases based on PRISMA inclusion and exclusion criteria...
November 17, 2016: World Neurosurgery
https://www.readbyqxmd.com/read/27866915/trends-in-transcranial-doppler-monitoring-in-aneurysmal-subarachnoid-hemorrhage-a-10-year-analysis-of-the-nationwide-inpatient-sample
#5
Gyanendra Kumar, Karen C Albright, John P Donnelly, Angela Hays Shapshak, Mark R Harrigan
BACKGROUND: Transcranial Doppler (TCD) is endorsed by national guidelines for use in aneurysmal subarachnoid hemorrhage (aSAH) for surveillance of cerebral vasospasm (CV). However, nationwide data on utilization of TCD for CV detection and monitoring in aSAH are lacking. METHODS: Analysis of nationwide trends in TCD prevalence was performed using Nationwide Inpatient Sample (NIS) data from 2002 to 2011. Raw counts were converted into weighted counts, which were used to generate national estimates...
November 17, 2016: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/27865517/effects-of-melatonin-in-the-treatment-of-asthenia-in-aneurysmal-subarachnoid-hemorrhage
#6
V Gilard, F-X Ferracci, O Langlois, S Derrey, F Proust, S Curey
BACKGROUND AND OBJECTIVES: Survivors of aneurysmal subarachnoid hemorrhage (aSAH) commonly experience sleep disorders resulting in asthenia. The objective of this prospective study was to determine, in a cohort of patients with treated ruptured intracranial aneurysm (IA), the proportion of asthenia at 2months, in a cohort of patients treated with melatonin and in a control cohort. PATIENTS AND METHODS: Twenty consecutive patients admitted for the treatment of ruptured IA and able to answer a standardized questionnaire were included in the study...
December 2016: Neuro-Chirurgie
https://www.readbyqxmd.com/read/27858393/the-clinical-predictors-of-shunt-dependent-hydrocephalus-following-aneurysmal-subarachnoid-hemorrhage
#7
Sio Iong Chang, David Hung-Tsang Yen, Ming Dar Tsai, Cheng-Ta Hsieh
AIM: Shunt-dependent hydrocephalus (SDH) is a relatively common complication following aneurysmal subarachnoid hemorrhage (aSAH). Delay in diagnosis and treatment may worsen neurological outcome. This study was conducted to identify early clinical factors associated with SDH following aSAH. MATERIAL AND METHODS: Patients diagnosed with aSAH at our hospital from January 2010 through July 2014 were included. Patients aged ≤ 18 or ≥ 90 year, with concurrent arteriovenous malformation, treated with both clipping and coiling, or not receiving definitive treatment were excluded...
October 17, 2016: Turkish Neurosurgery
https://www.readbyqxmd.com/read/27847764/procedure-related-complication-rate-for-the-endovascular-treatment-of-aneurysmal-subarachnoid-hemorrhage-under-local-anesthesia
#8
Soo-Dong Park, Jong-Hoon Kim, Chul-Hoon Chang, Young-Jin Jung
OBJECTIVE: To report the procedure related complication rate of endovascular treatments (EVTs) performed on patients with aneurysmal subarachnoid hemorrhage (aSAH) under local anesthesia (LA). MATERIALS AND METHODS: This study enrolled 186 patients who underwent EVT for ruptured aneurysm under LA from January 2009 to December 2013. Procedure-related complications rate and factors associated with it were analyzed depending on the patients' factors, aneurysm factors and physician factors...
September 2016: Journal of Cerebrovascular and Endovascular Neurosurgery
https://www.readbyqxmd.com/read/27847761/efficacy-of-pre-procedural-rehydration-against-thromboembolic-complications-for-ruptured-aneurysm-embolization
#9
Soo-Dong Park, Young-Jin Jung
OBJECTIVE: To report effects of the pre-procedural rehydration for reduce thromboembolic complications in acute phase aneurysmal subarachnoid hemorrhage coil embolization. MATERIALS AND METHODS: From January 2009 to December 2013, 190 patients with ruptured aneurysmal subarachnoid hemorrhage (aSAH) treated by coil embolization at our institution were consecutively enrolled in this study. In period 1 (from January 2009 to June 2012, n = 122), pre-procedural fluid was not supplied...
September 2016: Journal of Cerebrovascular and Endovascular Neurosurgery
https://www.readbyqxmd.com/read/27799919/feasibility-of-magnetoencephalography-after-endovascular-treatment-of-ruptured-intracranial-aneurysms
#10
Leodante da Costa, Benjamin T Dunkley, Allison Bethune, Amanda Robertson, Matt MacDonald, Elizabeth Pang
OBJECTIVE: Among good outcome survivors of aneurysmal subarachnoid hemorrhage (aSAH), only 23% have normal neurocognitive performance, despite imaging that is often normal. The aim of this work is to explore the use of magnetoencephalography (MEG) after endovascular treatment of ruptured aneurysms. METHODS: Good outcome aSAH patients treated with coiling and matched controls were recruited. Clinical assessments and resting-state MEG and anatomical MRI images were obtained...
2016: Frontiers in Neurology
https://www.readbyqxmd.com/read/27781149/prognostic-value-of-plasma-galectin-3-levels-after-aneurysmal-subarachnoid-hemorrhage
#11
Hua Liu, Yong Liu, Jinbing Zhao, Hongyi Liu, Shengxue He
BACKGROUND: Inflammatory responses are correlated with secondary brain injury after aneurysmal subarachnoid hemorrhage (aSAH). Galectin-3 (Gal-3) is a novel biomarker reflecting inflammation status, and its elevated circulating levels are associated with poor prognosis of some inflammatory diseases. The aim of this study was to evaluate the relationship between Gal-3 plasma levels and prognosis in a group of aSAH patients. MATERIALS AND METHODS: We assessed plasma Gal-3 levels in 120 patients and 120 healthy individuals...
October 2016: Brain and Behavior
https://www.readbyqxmd.com/read/27776892/computed-tomography-perfusion-deficits-during-the-baseline-period-in-aneurysmal-subarachnoid-hemorrhage-are-predictive-of-delayed-cerebral-ischemia
#12
Yuxia Duan, Haoli Xu, Rui Li, Kuikui Zheng, Zilong Hu, Nan Wu, Yunjun Yang, Qichuan Zhuge, Weijian Chen
BACKGROUND AND PURPOSE: Delayed cerebral ischemia (DCI) is a frequent and fearful complication following aneurysmal subarachnoid hemorrhage (aSAH). The aim of this study is to assess the diagnostic accuracy of computed tomography perfusion (CTP) during an admission baseline period for the prediction of DCI. METHODS: Fifty-four aSAH cases were screened by baseline CTP within 3 days after aSAH and were reexamined with CTP 7-17 days after aSAH. Relative cerebral blood volume, relative cerebral blood flow (CBF), and relative mean transit time were measured...
October 21, 2016: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/27759872/surgical-timing-for-aneurysmal-subarachnoid-hemorrhage-a-meta-analysis-and-systematic-review
#13
Zhao Chenhui, Wei Yi
BACKGROUND: Despite great advances in treatment of Aneurysmal subarachnoid hemorrhage (aSAH), yet, a consensus as to the most optimal timing of surgery has not been reached. MATERIALS AND METHODS: PubMed and the Cochrane Library were searched for English-language studies published up to May 2015. Before conducting the meta-analysis, the studies were evaluated for publication bias and heterogeneity. Fixed and random effect models were used to estimate relative risks (RR) and the corresponding 95% confidence intervals (CIs)...
December 7, 2015: Turkish Neurosurgery
https://www.readbyqxmd.com/read/27756669/vitamin-d-deficiency-is-not-associated-with-outcomes-in-aneurysmal-subarachnoid-hemorrhage-patients-a-case-control-study
#14
Yarelis Alvarado Reyes, Alexandra Perez, Gloria Rodriguez-Vega
OBJECTIVE: Vitamin D deficiency has been associated with increased risk and adverse outcomes in many clinical settings including cardiovascular disease, stroke, and critically ill patients. Therefore we aimed to determine whether vitamin D deficiency had any effect in aneurysmal subarachnoid hemorrhage (aSAH) clinical outcomes. METHODS: A retrospective record review was conducted in a tertiary community hospital in Puerto Rico. Adult patients admitted to the neurosurgical intensive care unit (NICU) with a diagnosis of aSAH from January 2013 to July 2014, who had a 25-hydroxyvitamin-D level drawn, were included...
October 15, 2016: World Neurosurgery
https://www.readbyqxmd.com/read/27754735/acute-hormonal-findings-after-aneurysmal-subarachnoid-hemorrhage-report-from-a-single-center
#15
Riikka S K Takala, Riku Kiviranta, Klaus T Olkkola, Tero Vahlberg, Dan Laukka, Anna Kotkansalo, Melissa Rahi, Matti Sankinen, Jussi Posti, Ari Katila, Jaakko Rinne
PURPOSE: The aim was to assess anterior pituitary hormone levels during the acute phase of aneurysmal subarachnoid hemorrhage (aSAH) and analyze the possible association with the clinical condition and outcome. MATERIAL AND METHODS: Forty patients with aSAH whose aneurysm was secured by endovascular coiling were enrolled. Basal secretions of cortisol, testosterone, luteinizing hormone (LH), prolactin (PRL), and sex hormone binding globulin (SHBG) levels were measured up to 14 days after the incident...
October 18, 2016: Endocrine Research
https://www.readbyqxmd.com/read/27717776/predictors-of-delayed-cerebral-ischemia-in-aneurysmal-subarachnoid-hemorrhage-patients-with-asymptomatic-angiographic-vasospasm-on-admission
#16
Abdulrahman Aldakkan, Alireza Mansouri, Blessing N R Jaja, Naif M Alotaibi, R Loch Macdonald
BACKGROUND: Risk of delayed cerebral ischemia (DCI) in aneurysmal subarachnoid hemorrhage (aSAH) patients with asymptomatic angiographic vasospasm on admission is unclear in the literature. The goal of this study is to identify predictors of clinical DCI in this group of patients. METHOD: ology: An exploratory subgroup analysis was conducted in the Subarachnoid Hemorrhage International Trialists (SAHIT) data repository to identify predictors of clinical DCI in good-grade aSAH patients (World Federation of Neurological Surgeons (WFNS) grade I and II) with angiographic vasospasm on admission...
October 4, 2016: World Neurosurgery
https://www.readbyqxmd.com/read/27695237/determining-rural-risk-for-aneurysmal-subarachnoid-hemorrhages-a-structural-equation-modeling-approach
#17
Linda Jayne Nichols, Seana Gall, Christine Stirling
An aneurysmal subarachnoid hemorrhage (aSAH) carries a high disability burden. The true impact of rurality as a predictor of outcome severity is unknown. Our aim is to clarify the relationship between the proposed explanations of regional and rural health disparities linked to severity of outcome following an aSAH. An initial literature search identified limited data directly linking geographical location, rurality, rural vulnerability, and aSAH. A further search noting parallels with ischemic stroke and acute myocardial infarct literature presented a number of diverse and interrelated predictors...
October 2016: Journal of Neurosciences in Rural Practice
https://www.readbyqxmd.com/read/27670264/a-strategy-to-expeditious-invasive-treatment-improves-clinical-outcome-in-comatose-patients-with-aneurysmal-subarachnoid-haemorrhage
#18
J Hoogmoed, R van den Berg, B A Coert, G J E Rinkel, W P Vandertop, D Verbaan
BACKGROUND: In patients with poor clinical condition after aneurysmal subarachnoid haemorrhage (aSAH), treatment is often deferred until patients show signs of improvement. Early external ventricular drainage and aneurysm occlusion may improve prognosis also in poor grade patients. The clinical outcome of an expeditious approach was compared with that of a conservative approach. METHODS: In all, 285 consecutive World Federation of Neurological Surgeons (WFNS) grade V aSAH patients admitted to three university hospitals between January 2000 and June 2007 were included...
September 26, 2016: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/27647028/primary-hemorrhagic-neurovascular-diseases-phnvds-in-tibetans-a-retrospective-observational-study
#19
Anqi Xiao, Ruiqi Chen, Hao Li, Lu Ma, Sen Lin, Xin Hu, Chao You
BACKGROUND: Although there have been many studies on primary hemorrhagic neurovascular diseases (PHNVDs) in different populations, a study focusing on PHNVDs in Tibetan people was still lacking. This study aimed to explore the notable characteristics of Tibetan PHNVDs by comparing the most three common PHNVDs (aneurysmal subarachnoid hemorrhage, spontaneous intracerebral hemorrhage and arteriovenous malformation) in our institution between Tibetan and Han patients. METHODS: In this retrospective observational study, the hospital information system (HIS) was utilized to access the records of patients with PHNVDs...
September 16, 2016: World Neurosurgery
https://www.readbyqxmd.com/read/27639370/synthesis-in%C3%A2-vitro-anticancer-and-antibacterial-activities-and-in-silico-studies-of-new-4-substituted-1-2-3-triazole-coumarin-hybrids
#20
Tatjana Gazivoda Kraljević, Anja Harej, Mirela Sedić, Sandra Kraljević Pavelić, Višnja Stepanić, Domagoj Drenjančević, Jasminka Talapko, Silvana Raić-Malić
The 4-substituted 1,2,3-triazole core in designed coumarin hybrids (4-35) with diverse physicochemical properties was introduced by eco-friendly copper(I)-catalyzed Huisgen 1,3-dipolar cycloaddition under microwave irradiation. Coumarin-1,2,3-triazole-benzofused heterocycle hybrids emerged as the class of compounds exhibiting the highest antiproliferative activity. The strong relationship between lipophilicity and antiproliferative activities was observed indicating that lipophilic 1,2,3-triazole-coumarin hybrids containing phenylethyl (13), 3,5-difluorophenyl (14), 5-iodoindole (30) and benzimidazole (33 and 35) subunits showed the most potent cytostatic effects...
August 31, 2016: European Journal of Medicinal Chemistry
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