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Supratentorial tumor

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https://www.readbyqxmd.com/read/29742589/clinical-factors-associated-with-icu-specific-care-following-supratentoral-brain-tumor-resection-and-validation-of-a-risk-prediction-score
#1
Lynze R Franko, Todd Hollon, Joseph Linzey, Christopher Roark, Venkatakrishna Rajajee, Kyle Sheehan, Magnus Teig, Shawn Hervey-Jumper, Jason Heth, Daniel Orringer, Craig A Williamson
OBJECTIVES: The postoperative management of patients who undergo brain tumor resection frequently occurs in an ICU. However, the routine admission of all patients to an ICU following surgery is controversial. This study seeks to identify the frequency with which patients undergoing elective supratentorial tumor resection require care, aside from frequent neurologic checks, that is specific to an ICU and to determine the frequency of new complications during ICU admission. Additionally, clinical predictors of ICU-specific care are identified, and a scoring system to discriminate patients most likely to require ICU-specific treatment is validated...
May 7, 2018: Critical Care Medicine
https://www.readbyqxmd.com/read/29732137/anaplasic-astrocytoma-with-exophytic-growth-in-sylvian-fissure-in-a-pediatric-patient-a-case-report
#2
José Raúl Guerra-Mora, Ulises Bravo-Ángel, Rodrigo Efraín Hernández-Reséndiz, Rosa María Vicuña-González, Jessica Frías-Guillén, Irina Jeanette Bercholc-Urinowsky, Carlos Cesar Bravo-Reyna, Ulises García-González
Gliomas are the most frequent supratentorial intracranial tumors in the pediatric population. Usually, they are intra-axial lesions with a characteristic image pattern, however, there are few reported cases of gliomas with exophytic growth. There are no previous reports in the literature of gliomas with exophytic growth in the Sylvian fissure. Fourteen year-old female patient who started with seizures. In imaging studies, a neoplasic mass with an exophytic portion in the left Sylvian fissure was found. Macroscopically, total resection was performed, definitive diagnosis was anaplastic astrocytoma...
April 2018: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/29727696/h3-k27-m-mutant-diffuse-midline-gliomas-in-different-anatomical-locations
#3
Leiming Wang, Zhuo Li, Ming Zhang, Yueshan Piao, Li Chen, Huiying Liang, Yukui Wei, Zeliang Hu, Lihong Zhao, Lianghong Teng, Dehong Lu
The histone H3 K27 M mutation has been frequently reported in the majority of diffuse midline gliomas. However, the relationship between the H3 K27 M mutation and clinical outcomes of gliomas from different anatomical locations is still not fully understood. A total of 120 patients with diffuse midline gliomas were selected for this retrospective observational study. The status of H3 K27 M, ATRX, TP53 and IDH was evaluated using immunohistochemistry and Sanger sequencing. Of the 120 cases aged from 4 to 76years (median=27years), 61 (50...
May 1, 2018: Human Pathology
https://www.readbyqxmd.com/read/29725181/supratentorial-pure-cortical-ependymoma-an-unusual-lesion-causing-focal-motor-aware-seizure
#4
Manish Beniwal, Ajit Mishra, K V L Narasinga Rao, Vikas Vazhayil, Bevinahalli N Nandeesh, Sampath Somanna
Ependymomas usually arise from the ependymal lining cells of the ventricular system and central canal of the spinal cord. Supratentorial ependymoma is a rare entity with the variable clinical course. In a small number of cases, ependymoma arises from supratentorial parenchyma. Only a few cases are reported in the literature. We report a case of 3-year-old girl with left frontal mass. Total removal of the mass lesion was performed without any neurological deficit. Pathological examination of the excised tumor was consistent with anaplastic ependymoma...
April 2018: Journal of Neurosciences in Rural Practice
https://www.readbyqxmd.com/read/29712529/cost-effectiveness-development-for-the-postoperative-care-of-craniotomy-patients-a-safe-transitions-pathway-in-neurological-surgery
#5
Joseph A Osorio, Michael M Safaee, Jennifer Viner, Sujatha Sankaran, Sarah Imershein, Ezekiel Adigun, Gabriela Weigel, Mitchel S Berger, Michael W McDermott
OBJECTIVE The authors' institution is in the top 5th percentile for hospital cost in the nation, and the neurointensive care unit (NICU) is one of the costliest units. The NICU is more expensive than other units because of lower staff/patient ratio and because of the equipment necessary to monitor patient care. The cost differential between the NICU and Neuro transitional care unit (NTCU) is $1504 per day. The goal of this study was to evaluate and to pilot a program to improve efficiency and lower cost by modifying the postoperative care of patients who have undergone a craniotomy, sending them to the NTCU as opposed to the NICU...
May 2018: Neurosurgical Focus
https://www.readbyqxmd.com/read/29707472/bilateral-supratentorial-subdural-hematomas-after-craniotomy-for-posterior-fossa-tumor-removal
#6
Aikaterini Solomou, Pantelis Kraniotis, George Bonanos, Constantine Constantoyannis
A 69-year-old man was admitted to the emergency department with headache and dizziness. He was submitted to brain computed tomography (CT) which showed a tumor in the right cerebellar hemisphere, findings which were subsequently confirmed with magnetic resonance imaging (MRI). He underwent a paramedian suboccipital craniotomy for removal of the mass. Histology confirmed the presence of a hemangiopericytoma. The patient was discharged 5 days postoperatively with improvement in his symptoms. Fifteen days later, he presented with gait difficulties...
April 2018: Journal of Neurological Surgery Reports
https://www.readbyqxmd.com/read/29697464/incidence-and-risk-factors-for-intraoperative-seizures-during-elective-craniotomy
#7
Rachel Kutteruf, Jen-Ting Yang, James G Hecker, Gregory A Kinney, Michele A Furman, Deepak Sharma
BACKGROUND: Perioperative seizures may affect 1% to 50% of patients undergoing craniotomy and adversely impact outcomes. However, data on intraoperative seizures are limited. This retrospective case-control study investigated the incidence and risk factors for intraoperative seizures during elective supratentorial craniotomy involving evoked potential monitoring. MATERIALS AND METHODS: Patients aged 18 years or above undergoing elective supratentorial craniotomy with evoked potential monitoring who experienced intraoperative seizures at our institution between December 2008 and March 2014 were compared with a control group generated using a random number generator...
April 24, 2018: Journal of Neurosurgical Anesthesiology
https://www.readbyqxmd.com/read/29682026/prognostic-implications-of-histological-clear-cells-in-high-grade-intracranial-ependymal-tumors-a-retrospective-analysis-from-a-tertiary-care-hospital-in-pakistan
#8
Fauzan Alam Hashmi, Hamid Hussain Rai, Muhammad Faheem Khan, Muhammad Ehsan Bari
Background: Clear cell variant in ependymal tumors is rare. We aimed to compare the features and outcome of the World Health Organization (WHO) Grade 3 ependymal tumors with clear cells to the WHO Grade 3 classic anaplastic ependymoma (AE). Materials and Methods: A retrospective cohort study conducted at the Department of Neurosurgery, Aga Khan University, Pakistan, from 2003 to 2013. The medical records and radiology of patients with proven histopathology were reviewed...
April 2018: Asian Journal of Neurosurgery
https://www.readbyqxmd.com/read/29680921/neurosurgical-treatment-of-gangliogliomas-in-children-and-adolescents-long-term-follow-up-of-a-single-institution-series-of-32-patients
#9
Tryggve Lundar, Bernt Johan Due-Tønnessen, Radek Fric, Arild Egge, Bård Krossnes, Paulina Due-Tønnessen, Einar Stensvold, Petter Brandal
OBJECT: The object of this study was to delineate long-term results of the surgical treatment of pediatric tumors classified as ganglioglioma or gangliocytoma. METHODS: A cohort of consecutive patients 19 years or younger who had undergone primary resection of CNS tumors during the years 1980-2016 at a single institution were reviewed in this retrospective study of surgical morbidity, mortality, and academic achievement and/or work participation. Gross motor function and activities of daily living were scored using the Barthel Index (BI)...
April 22, 2018: Acta Neurochirurgica
https://www.readbyqxmd.com/read/29678716/surgical-management-of-medial-tentorial-meningioma-falcotentorial-and-torcular
#10
Andrea Talacchi, Antonio Biroli, Aurel Hasanbelliu, Francesca Locatelli
BACKGROUND: Falcotentorial meningiomas (FTM) stand out for their rarity, inconsistent definition, and surgical complexity. It is appropriate to deal with them in the context of medial tentorial meningiomas (MTM). METHODS: Clinical and radiological characteristics of MTM, comprising the typical features of FTM and tentorial meningioma (TM) along with surgical management, short- and long-term outcomes, are reported . RESULTS: FTM (n=16) were typically supratentorial, large, edematous tumors that caused mainly headache and hemianopia; TM (n=12) were infratentorial, smaller not edematous tumors that caused mainly headache and gait ataxia...
April 17, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29670360/integrated-bioinformatic-analysis-unveils-significant-genes-and-pathways-in-the-pathogenesis-of-supratentorial-primitive-neuroectodermal-tumor
#11
Guang-Yu Wang, Ling Li, Bo Liu, Xiao Han, Chun-Hua Wang, Ji-Wen Wang
Purpose: This study aimed to explore significant genes and pathways involved in the pathogenesis of supratentorial primitive neuroectodermal tumor (sPNET). Materials and methods: Gene expression profile of GSE14295 was downloaded from publicly available Gene Expression Omnibus (GEO) database. Differentially expressed genes (DEGs) were screened out in primary sPNET samples compared with normal fetal and adult brain reference samples (sPNET vs fetal brain and sPNET vs adult brain)...
2018: OncoTargets and Therapy
https://www.readbyqxmd.com/read/29666881/pathological-factors-contributing-to-crossed-cerebellar-diaschisis-in-cerebral-gliomas-a-study-combining-perfusion-diffusion-and-structural-mr-imaging
#12
Xiaoxue Liu, Jianrui Li, Qiang Xu, Dante Mantini, Peng Wang, Yuan Xie, Yifei Weng, Chiyuan Ma, Kangjian Sun, Zhiqiang Zhang, Guangming Lu
PURPOSE: To investigate imaging features of crossed cerebellar diaschisis (CCD) in cerebral gliomas, and its underlying pathophysiological mechanisms. METHODS: Thirty-three pre-surgical patients with cerebral gliomas and 33 healthy controls underwent arterial spin-labeling, diffusion tensor imaging, and high-resolution T1-weighted imaging using MRI, in order to estimate cerebral blood flow (CBF), white matter integrity, and lesion volume, respectively. Asymmetry indices of CBF in the cerebellum were used for evaluating the level of CCD in the patients...
April 17, 2018: Neuroradiology
https://www.readbyqxmd.com/read/29656658/primary-angiitis-of-the-central-nervous-system-mimicking-a-cerebellar-tumor
#13
Guodong Zhang, Chunxia Yang, Jinjin Chang, Xunhui Yuan, Yun'an Bai, Jianyi Niu, Meiying Wang
Primary angiitis of the central nervous system (PACNS), is a rare and poorly understood disease mainly characterized by multifocal segmental inflammation of the small and medium vessels of the central nervous system. Most PACNS are multiple lesions, occurring in the supratentorial subcortical and deep white matter, and only a few cases present as a tumor-like mass lesion. Herein, we describe an extremely rare case of PACNS occurred in the cerebellum, which mimicked a cerebellar tumor. To the best of our knowledge, this is the first reported case of cerebellar tumor-like PACNS proved by histopathological examination...
April 14, 2018: British Journal of Neurosurgery
https://www.readbyqxmd.com/read/29644158/bilateral-simultaneous-temporal-relapses-of-medulloblastoma
#14
Mauricio Martinez-Moreno, Olga O Galván de la Cruz, Christian H Flores-Balcázar, Samuel Rosales-Pérez, Daniel Rembao-Bojórquez, Sergio Moreno-Jiménez
Supratentorial relapses are a common component of medulloblastoma after failure of treatment. Craniospinal irradiation (CSI) to cerebrospinal fluid-bearing areas is an essential part of the management of these tumors both in adults and children. Failure of treatment in specific anatomical regions can be attributable to technical inaccuracies in CSI technique leading to radiation underdosing in such areas. We present two cases of patients with bilateral simultaneous metastasis of a primary medulloblastoma treated, in both cases, four years before the recurrence...
February 8, 2018: Curēus
https://www.readbyqxmd.com/read/29626688/the-houdini-tumor-a-case-report-and-literature-review-of-pregnancy-associated-meningiomas
#15
Vikram Chakravarthy, Brett Kaplan, Vadim Gospodarev, Hannah Myers, Kenneth De Los Reyes, Adina Achiriloaie
BACKGROUND: Meningiomas are common intracranial neoplasms of undetermined etiology. Accelerated growth during episodes of elevated serum estrogen and progesterone have been demonstrated in pregnant patients, as exhibited by an overexpression of estrogen or progesterone upon immunohistochemical analysis. This case report and literature review describes a case of complete meningioma regression in a postpartum patient. CASE DESCRIPTION: A 23-year-old female presented at 37 weeks of pregnancy with 1-month history of fluctuating severe left-sided headaches, periodic blurry vision, nausea and vomiting...
April 4, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29617945/intracranial-neoplasms-in-the-first-year-of-life-results-of-a-third-cohort-of-patients-from-a-single-institution
#16
Sebastian M Toescu, Gregory James, Kim Phipps, Owase Jeelani, Dominic Thompson, Richard Hayward, Kristian Aquilina
BACKGROUND: Brain tumors in the first year of life are rare and their management remains challenging. OBJECTIVE: To report on the contemporary management of brain tumors in infants with reference to previous series from our institution. METHODS: Retrospective cohort study design. Electronic/paper case note review of all brain tumors diagnosed at our institution in children aged <1 yr since the publication of our previous series. RESULTS: Ninety-eight patients were seen...
April 3, 2018: Neurosurgery
https://www.readbyqxmd.com/read/29615337/immunohistochemical-and-molecular-genetic-study-on-epithelioid-glioblastoma-series-of-seven-cases-with-review-of-literature
#17
Gaurav Khanna, Pankaj Pathak, Vaishali Suri, Mehar Chand Sharma, Sujata Chaturvedi, Arvind Ahuja, M Bhardwaj, Ajay Garg, Chitra Sarkar, Rajeev Sharma
Epithelioid glioblastoma (e-gbm) is a recently described variant of glioblastoma (GBM) which is associated with short survival and now added as a provisional entity to WHO 2016 classification of CNStumors. About half of these tumors show characteristic BRAF-V600E mutation. However, unlike conventional GBMs, e-gbm lack specific diagnostic and prognostic markers. Hence, we aimed to molecularly characterize these tumors. An extensive review of literature was performed.In a multi-institutional effort, all the cases of glioblastoma of year 2017 were reviewed...
March 22, 2018: Pathology, Research and Practice
https://www.readbyqxmd.com/read/29590736/incidence-of-central-nervous-system-tumors-in-patients-hospitalized-at-split-university-hospital-centre-during-a-ten-year-period-january-1-2004-december-31-2013
#18
Maja Mizdrak, Gordan Džamonja, Petar Filipović Grčić
The aim was to evaluate the incidence and characteristics of central nervous system tumors in patients hospitalized at the Department of Neurology, Split University Hospital Centre, during a 10-year period. The study included data on 859 patients with the diagnosis of central nervous system (CNS) tumor. Diagnosis was based on the routine CNS neuroimaging methods (computed tomography/magnetic resonance imaging). Access to patient medical records provided demographic and clinical data, continued by collection of data on potential lethal outcome of patients at the Registrar's Office...
December 2017: Acta Clinica Croatica
https://www.readbyqxmd.com/read/29581920/first-clinical-applications-of-a-high-definition-three-dimensional-exoscope-in-pediatric-neurosurgery
#19
Thomas Beez, Christopher Munoz-Bendix, Kerim Beseoglu, Hans-Jakob Steiger, Sebastian A Ahmadi
The ideal visualization tools in microneurosurgery should provide magnification, illumination, wide fields of view, ergonomics, and unobstructed access to the surgical field. The operative microscope was the predominant innovation in modern neurosurgery. Recently, a high-definition three-dimensional (3D) exoscope was developed. We describe the first applications in pediatric neurosurgery. The VITOM 3D exoscope (Karl Storz GmbH, Tuttlingen, Germany) was used in pediatric microneurosurgical operations, along with an OPMI PENTERO operative microscope (Carl Zeiss AG, Jena, Germany)...
January 24, 2018: Curēus
https://www.readbyqxmd.com/read/29579305/seizure-outcomes-of-supratentorial-brain-tumor-resection-in-pediatric-patients
#20
Fadi S Saadeh, Edward F Melamed, Nolan D Rea, Mark D Krieger
Background: This study aims to identify the prevalence of and risk factors for seizure development after supratentorial brain tumor resection in pediatric patients. This could be used to guide the postoperative management and usage of anti-epileptic drugs (AEDs). Methods: Retrospective study was conducted for patients between 0 and 21 years with supratentorial tumor resection between 2005 and 2015 at a single institution. Results: Two hundred patients (114 males/86 females) were identified...
March 20, 2018: Neuro-oncology
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