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Supratentorial tumor

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https://www.readbyqxmd.com/read/27894359/can-morphological-mri-differentiate-between-primary-central-nervous-system-lymphoma-and-glioblastoma
#1
H Malikova, E Koubska, J Weichet, J Klener, A Rulseh, R Liscak, Z Vojtech
BACKGROUND: Primary central nervous system lymphoma (PCNSL) is a rare, aggressive brain neoplasm that accounts for roughly 2-6% of primary brain tumors. In contrast, glioblastoma (GBM) is the most frequent and severe glioma subtype, accounting for approximately 50% of diffuse gliomas. The aim of the present study was to evaluate morphological MRI characteristics in histologically-proven PCNSL and GBM at the time of their initial presentation. METHODS: We retrospectively evaluated standard diagnostic MRI examinations in 54 immunocompetent patients (26 female, 28 male; age 62...
November 29, 2016: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://www.readbyqxmd.com/read/27890753/geographically-remote-cerebral-venous-sinus-thrombosis-in-patients-with-intracranial-tumors
#2
Daniel M S Raper, Alicia M Zukas, David Schiff, Ashok R Asthagiri
Cerebral venous sinus thrombosis (CVST) related to intracranial tumors has most commonly been recognized as an operative complication related to local operative factors such as retraction or direct venous injury. CVST may also be caused by tumor related factors such as local mass effect, but rarely occurs geographically remote from the site of the tumor. We report six cases treated at our institution of intracranial supratentorial tumors associated with CVST. In each case, the CVST was remote from the surgical site...
November 24, 2016: World Neurosurgery
https://www.readbyqxmd.com/read/27889023/supratentorial-tumors-in-pediatric-patients
#3
REVIEW
Carlos Zamora, Thierry A G M Huisman, Izlem Izbudak
The breadth of tumors that can arise in the supratentorial brain in children is extensive. With the exception of those that result in seizures and the highly malignant histologies, supratentorial tumors may come to medical attention later compared with infratentorial tumors, as they are less commonly associated with ventricular obstruction. This article presents an overview of the neuroimaging characteristics of these entities, with particular attention to relevant features that may aid in narrowing the differential diagnosis, including correlation with demographics and clinical presentation...
February 2017: Neuroimaging Clinics of North America
https://www.readbyqxmd.com/read/27888628/impact-of-epidemiological-characteristics-of-supratentorial-gliomas-in-adults-brought-about-by-the-2016-world-health-organization-classification-of-tumors-of-the-central-nervous-system
#4
Haihui Jiang, Yong Cui, Junmei Wang, Song Lin
The latest World Health Organization (WHO) classification of tumors of the central nervous system (CNS) integrates both histological and molecular features in the definition of diagnostic entities. This new approach enrolls novel entities of gliomas. In this study, we aimed to reveal the epidemiological characteristics, including age at diagnosis, gender ratio, tumor distribution and survival, of these new entities. We retrospectively reclassified 1210 glioma samples according to the 2016 CNS WHO diagnostic criteria...
November 24, 2016: Oncotarget
https://www.readbyqxmd.com/read/27859957/retrospective-comparison-of-three-dimensional-conformal-radiation-therapy-vs-prednisolone-alone-in-30-cases-of-canine-infratentorial-brain-tumors
#5
Elisabetta Treggiari, Thomas W Maddox, Rita Gonçalves, Jerome Benoit, Julia Buchholz, Laura Blackwood
Infratentorial tumors are relatively infrequent in dogs and a lack of data makes it difficult to offer prognostic information. Untreated, dogs with these neoplasms have shorter survival times than those with supratentorial tumors. The role of radiation therapy (RT) in the management of infratentorial tumors is poorly defined and tumoral/peritumoral swelling in this site is a potential cause of serious acute side effects. The aim of this retrospective, cohort study was to describe cases of infratentorial tumors treated with fractionated three-dimensional conformal RT (3D CRT) and glucocorticoids (GC), and compare outcomes and survival with dogs affected by tumors in the same location that received GC alone...
November 15, 2016: Veterinary Radiology & Ultrasound
https://www.readbyqxmd.com/read/27857859/emergency-decompressive-craniectomy-after-removal-of-convexity-meningiomas
#6
Paolo Missori, Maurizio Domenicucci, Sergio Paolini, Cristina Mancarella, Serena Tola, Alessandro D'Elia, Nicola Marotta, Arsen Seferi, Vincenzo Esposito
BACKGROUND: Convexity meningiomas are benign brain tumors that are amenable to complete surgical resection and are associated with a low complication rate. The aim of this study was to identify factors that result in acute postoperative neurological worsening after the removal of convexity meningiomas. METHODS: Clinical evaluation and neuroradiological analysis of patients who underwent removal of a supratentorial convexity meningioma were reviewed. Patients were selected when their postoperative course was complicated by acute neurological deterioration requiring decompressive craniectomy...
2016: Surgical Neurology International
https://www.readbyqxmd.com/read/27854111/the-risk-of-hypotension-and-seizures-in-patients-receiving-prophylactic-anti-epileptic-drugs-for-supratentorial-craniotomy
#7
Julius Höhne, Karl M Schebesch, Christian Ott, Alexander Brawanski, Max Lange
BACKGROUND: Perioperative seizure prophylaxis with antiepileptic drugs (AED) has been advocated in patients undergoing supratentorial craniotomy. The practice remains controversial. The reasoning presupposes that the possibility of an adverse drug reaction from the AED is lower than the probability of harm from a seizure. Even short periods of hypotension during the operation can lead to acute kidney and myocardial injury. We retrospectively evaluated cardiovascular effects and tolerability of Levetiracetam (LEV) alone, LEV and Lacosamid (LCM) as compared to Phenytoin (PHT)...
November 17, 2016: Journal of Neurosurgical Sciences
https://www.readbyqxmd.com/read/27853494/preoperative-grading-of-astrocytic-supratentorial-brain-tumors-with-diffusion-weighted-magnetic-resonance-imaging-and-apparent-diffusion-coefficient
#8
Mahsa Raisi-Nafchi, Fariborz Faeghi, Alireza Zali, Hamidreza Haghighatkhah, Jalal Jalal-Shokouhi
BACKGROUND: Diffusion-weighted imaging (DWI) is a form of magnetic resonance imaging (MRI) based on measuring the random Brownian motion of water molecules within the biological tissues and is particularly useful in tumor characterization. OBJECTIVES: The purpose of this study was to evaluate the diagnostic value of DW MRI and the apparent diffusion coefficient (ADC) for preoperative grading of astrocytic supratentorial brain tumors. PATIENTS AND METHODS: Twenty-three patients (14 females, 9 males, mean age 43 years) with astrocytic supratentorial brain tumors underwent preoperative conventional MR imaging and DW MRI...
July 2016: Iranian Journal of Radiology: a Quarterly Journal Published By the Iranian Radiological Society
https://www.readbyqxmd.com/read/27845572/post-craniotomy-intracranial-infection-in-patients-with-brain-tumors-a-retrospective-analysis-of-5723-consecutive-patients
#9
Zhong-Hua Shi, Ming Xu, Yong-Zhi Wang, Xu-Ying Luo, Guang-Qiang Chen, Xin Wang, Tao Wang, Ming-Zhong Tang, Jian-Xin Zhou
AIM: To determine the risk factors for and the incidence, outcomes, and causative pathogens of post-craniotomy intracranial infection (PCII) in patients with brain tumors. METHODS: A retrospective study was performed of 5723 patients with brain tumors who were surgically treated between January 2012 and December 2013 in Beijing Tiantan Hospital. The patients' demographics, pathohistological diagnoses, surgical procedures, postoperative variables, causative pathogens, and outcomes were evaluated...
November 15, 2016: British Journal of Neurosurgery
https://www.readbyqxmd.com/read/27837434/prediction-of-genetic-subgroups-in-adult-supra-tentorial-gliomas-by-pre-and-intraoperative-parameters
#10
Shunsuke Nakae, Kazuhiro Murayama, Hikaru Sasaki, Masanobu Kumon, Yuya Nishiyama, Shigeo Ohba, Kazuhide Adachi, Shinya Nagahisa, Takuro Hayashi, Joji Inamasu, Masato Abe, Mitsuhiro Hasegawa, Yuichi Hirose
Recent progress in neuro-oncology has validated the significance of genetic diagnosis in gliomas. We previously investigated IDH1/2 and TP53 mutations via Sanger sequencing for adult supratentorial gliomas and reported that PCR-based sequence analysis classified gliomas into three genetic subgroups that have a strong association with patient prognosis: IDH mutant gliomas without TP53 mutations, IDH and TP53 mutant gliomas, and IDH wild-type gliomas. Furthermore, this analysis had a strong association with patient prognosis...
November 11, 2016: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/27821230/-primary-central-nervous-system-diffuse-large-b-cell-lymphoma-a-clinicopathologic-and-molecular-study
#11
Z P Ma, Babayi Ainiwaer, Z Y Liu, X L Shi, W L Cui, W Zhang, X X Li
Objective: To investigate clinicopathologic characteristics, immunophenotype and EB virus-related molecular genetic alterations in primary central nervous system diffuse large B cell lymphoma (DLBCL) along with correlation with clinical prognosis. Methods: A total of 30 cases of primary central nervous system DLBCL were retrospectively studied by retrieving clinical data, histological evaluation and immunophenotyping by EnVision two steps methods. The expression of EBER mRNA was detected by in situ hybridization and bcl-2, bcl-6 and C-MYC gene abnormalities were analyzed by interphase fluorescence in situ hybridization...
November 8, 2016: Zhonghua Bing Li Xue za Zhi Chinese Journal of Pathology
https://www.readbyqxmd.com/read/27799979/meningeal-hemangiopericytoma-in-33-year-old-female-a-case-report
#12
Alireza Abdollahi, Reyhaneh Abdollahpouri, Seyed-Mohammad Tavangar
Intracranial hemangiopericytomas (HPC) are rare vascular tumors. They account for 0.4% of primary central nervous system tumors. HPC is more commonly located supratentorially and tends to occur in a younger age group, with average age at presentation of 38-42 years. The tumor was found throughout the entire CNS, usually superficially and closely related to the meninges. Moreover, they have a strong tendency for local recurrence and extracranial metastasis. Given the clinical, pathological and imaging similarities between Hemangiopericytoma and angioblastic/anaplastic meningioma and the necessity of differentiating these two (choosing the proper treatment and prognosis), we present a report of meningeal Hemangiopericytoma tumor in a 33-year-old female...
2016: Iranian Journal of Pathology
https://www.readbyqxmd.com/read/27793766/poor-prognosis-and-challenging-treatment-of-optic-nerve-malignant-gliomas-literature-review-and-case-report-series
#13
Mohannat Alireza, Aymeric Amelot, Dorian Chauvet, Louis-Marie Terrier, Guillaume Lot, Olivier Bekaert
BACKGROUND: Malignant optic glioma of adulthood is a rare, invasive neoplasm of the anterior visual pathway. In this article, the clinical features of a case series of 3 malignant optic nerve glioblastomas (World Health Organization grade IV) are presented, and the modalities of treatment and their associated survivals are discussed through a review of the existing literature to date. METHODS: A retrospective case series study was led for 3 patients diagnosed with primary optic nerve and chiasm glioblastoma, coming from 2 referral neurosurgical centers...
October 25, 2016: World Neurosurgery
https://www.readbyqxmd.com/read/27778212/survival-after-chemotherapy-and-stem-cell-transplant-followed-by-delayed-craniospinal-irradiation-is-comparable-to-upfront-craniospinal-irradiation-in-pediatric-embryonal-brain-tumor-patients
#14
David R Raleigh, Bryan Tomlin, Benedict Del Buono, Erika Roddy, Katherine Sear, Lennox Byer, Erin Felton, Anu Banerjee, Joseph Torkildson, David Samuel, Biljana Horn, Steve E Braunstein, Daphne A Haas-Kogan, Sabine Mueller
Pediatric embryonal brain tumor patients treated with craniospinal irradiation (CSI) are at risk for adverse effects, with greater severity in younger patients. Here we compare outcomes of CSI vs. high-dose chemotherapy (HD), stem cell transplant (SCT) and delayed CSI in newly diagnosed patients. Two hundred one consecutive patients treated for medulloblastoma (72 %), supratentorial primitive neuroectodermal tumor (sPNET; 18 %) or pineoblastoma (10 %) at two institutions between 1988 and 2014 were retrospectively identified...
October 24, 2016: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/27765720/magnetic-resonance-guided-laser-ablation-for-the-treatment-of-recurrent-dural-based-lesions-a-series-of-five-cases
#15
Michael E Ivan, Roberto Jose Diaz, Michael H Berger, Gregory W Basil, David A Osiason, Thomas Plate, Amanda Wallo, Ricardo J Komotar
BACKGROUND AND OBJECTIVE: Magnetic resonance-guided laser-induced thermotherapy (MR-LITT) is a minimally invasive technique that shows promise in neuro-oncology due to its superiority in delivering precise minimally invasive thermal energy with minimal collateral damage. In this analysis we investigate initial data on MR-LITT's effect on dural based lesions. METHODS: Five patients were identified with dural based lesions (4 meningiomas, 1 solitary fibrous tumor) with clear evidence of radiological progression...
October 17, 2016: World Neurosurgery
https://www.readbyqxmd.com/read/27744078/tumor-location-and-survival-outcomes-in-adult-patients-with-supratentorial-glioblastoma-by-levels-of-toll-like-receptor-9-expression
#16
Linsen Mu, Yongzhi Wang, Yonggang Wang, Hongbo Zhang, Dewei Shang, Fuqiang Tan, Yan Li, Xuzhu Chen
INTRODUCTION: Toll-like receptor 9(TLR9) is a key immunotherapy target for glioblastoma (GBM). This study explored the correlation of TLR9 expression with tumor location and survival outcomes in patients with supratentorial GBM. METHODS: We retrospectively identified 46 patients with supratentorial GBMs and divided them into those with high (TRL9(High)) and low TLR9 (TRL9(Low)) levels. The two groups were compared by patients' ages, sex, preoperative Karnofsky Performance Score (KPS), resection extent, tumor location, progression-free survival (PFS) and overall survival (OS)...
October 12, 2016: World Neurosurgery
https://www.readbyqxmd.com/read/27743145/incidence-time-trends-and-survival-patterns-of-childhood-pilocytic-astrocytomas-in-southern-eastern-europe-and-seer-us
#17
Marios K Georgakis, Maria A Karalexi, Eleni I Kalogirou, Anton Ryzhov, Anna Zborovskaya, Nadya Dimitrova, Sultan Eser, Luis Antunes, Mario Sekerija, Tina Zagar, Joana Bastos, Domenic Agius, Margareta Florea, Daniela Coza, Evdoxia Bouka, Charis Bourgioti, Helen Dana, Emmanuel Hatzipantelis, Maria Moschovi, Savvas Papadopoulos, Georgios Sfakianos, Evgenia Papakonstantinou, Sophia Polychronopoulou, Spyros Sgouros, Kalliopi Stefanaki, Eftichia Stiakaki, Katerina Strantzia, Basilios Zountsas, Apostolos Pourtsidis, Eustratios Patsouris, Eleni Th Petridou
Pilocytic astrocytomas (PA) comprise the most common childhood central nervous system (CNS) tumor. Exploiting registry-based data from Southern and Eastern Europe (SEE) and SEER, US, we opted to examine incidence, time trends, survival and tentative outcome disparities of childhood PA by sociodemographic and clinical features. Childhood PA were retrieved from 12 SEE registries (N = 552; 1983-2014) and SEER (N = 2723; 1973-2012). Age-standardized incidence rates (ASR) were estimated and survival was examined via Kaplan-Meier and Cox regression analysis...
October 14, 2016: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/27721314/gamma-knife-surgery-for-recurrent-or-residual-supratentorial-primitive-neuroectodermal-tumors
#18
Young-Bem Se, Dong Gyu Kim, Sung Kwon Kim, Jin Wook Kim, Yong Hwy Kim, Chul-Kee Park, Hyun-Tai Chung, Sun-Ha Paek
BACKGROUND: Supratentorial primitive neuroectodermal tumors (PNETs) are highly malignant and rare tumors of the central nervous system. OBJECTIVES: The aim of this study was to determine the role of Gamma Knife surgery (GKS) as a salvage treatment option for patients with recurrent or residual supratentorial PNETs. METHODS: Between 1998 and 2014, 11 patients with supratentorial PNETs were retrospectively analyzed. This series consisted of 7 male and 4 female patients...
2016: Stereotactic and Functional Neurosurgery
https://www.readbyqxmd.com/read/27668845/desmoplastic-infantile-astrocytoma-and-ganglioglioma-case-report-and-review-of-the-literature
#19
Alaa Samkari, Faris Alzahrani, Abeer Almehdar, Hussein Algahtani
Desmoplastic infantile astrocytoma (DIA) is a rare, supratentorial, dural-based, large cystic tumor that usually arises in the first 24 months of life. However, non-infantile cases were also reported in the literature. Desmoplastic infantile astrocytoma and desmoplastic infantile ganglioglioma (DIG) are both classified as grade I astrocytoma by the World Health Organization (WHO). Grossly, DIA/DIG are large tumors composed of solid and cystic portions. Although large in nature, they are slow-growing tumors, with good prognosis after complete surgical removal, and rarely require a chemotherapy or radiotherapy...
September 26, 2016: Clinical Neuropathology
https://www.readbyqxmd.com/read/27666131/postoperative-seizure-control-in-patients-with-tumor-associated-epilepsy
#20
Andrew Neal, Andrew Morokoff, Terence John O'Brien, Patrick Kwan
OBJECTIVE: The patterns of postoperative seizure control and response to antiepileptic drugs (AEDs) in tumor-associated epilepsy (TAE) are poorly understood. We aim to document these characteristics in patients with supratentorial gliomas. METHODS: This was a retrospective analysis of 186 patients with supratentorial gliomas. Seizure patterns were classified into four groups: A, no postoperative seizure; B, early postoperative seizure control within 6 months; C, fluctuating seizure control; and D, never seizure-free...
November 2016: Epilepsia
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