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Gross Motor Development

Cristina Paules, Victoria Pueyo, Elena Martí, Susana Vilchez, Irina Burd, Pilar Calvo, Daniel Oros
BACKGROUND: Threatened preterm labor is a leading cause of hospital admission during pregnancy. Patients presenting with an episode of threatened preterm labor who deliver at term are considered to have false preterm labor. However, threatened preterm labor has been proposed as a pathological insult that is not always sufficient to induce irreversible spontaneous preterm birth but that could alter the normal course of pregnancy. OBJECTIVE: The aim of this study was to evaluate threatened preterm labor during pregnancy as a risk factor of neurodevelopmental deficits of children at 2 years of age...
October 22, 2016: American Journal of Obstetrics and Gynecology
M Salavati, E A A Rameckers, A Waninge, W P Krijnen, B Steenbergen, C P van der Schans
PURPOSE: To investigate whether the adapted version of the Gross Motor Function Measure-88 (GMFM-88) for children with Cerebral Palsy (CP) and Cerebral Visual Impairment (CVI) results in higher scores. This is most likely to be a reflection of their gross motor function, however it may be the result of a better comprehension of the instruction of the adapted version. METHOD: The scores of the original and adapted GMFM-88 were compared in the same group of children (n=21 boys and n=16 girls), mean (SD) age 113 (30) months with CP and CVI, within a time span of two weeks...
October 19, 2016: Research in Developmental Disabilities
S Micheletti, F Palestra, P Martelli, P Accorsi, J Galli, L Giordano, V Trebeschi, E Fazzi
BACKGROUND: Angelman Syndrome (AS) is a rare neurodevelopment disorder resulting from deficient expression or function of the maternally inherited allele of UBE3A gene. The aim of the study is to attempt at providing a detailed definition of neurodevelopmental profile in AS, with particular regard to motor, cognitive, communicative, behavioural and neurovisual, features by using standardized instruments. METHOD: A total of ten subjects aged from 5 to 11 years (4 males and 6 females) with molecular confirmed diagnosis of AS (7 15q11...
October 21, 2016: Italian Journal of Pediatrics
Marybeth Grant-Beuttler, Jenifer Jennings, Christina McCauley, Robert Dulay, Katlyn Grossnickle, Kerri Kill, John Hay
PURPOSE: To develop an electronic version of the Children's Self-Perceptions of Adequacy in and Predilection for Physical Activity (eCSAPPA), which would allow individual administration to children younger than nine years of age. METHODS: Fifty-four, four - nine-year-old children completed the eCSAPPA and the Test of Gross Motor Development-2 (TGMD-2). Parental measures of physical activity, and body mass index were obtained. Twenty-one participants additionally completed the paper version of the CSAPPA...
October 21, 2016: Pediatric Exercise Science
Naseem Jamnia, Janice H Urban, Grace Beth Stuzmann, Sarah Chiren, Emily Reisenbigler, Robert Marr, Daniel A Peterson, Dorothy A Kozlowski
Repeat concussions (RC) can result in significant long-term neurological consequences and increased risk for neurodegenerative disease compared to single concussion (SC). Mechanisms underlying this difference are poorly understood and best elucidated using an animal model. To the best of our knowledge, there is no closed-head model in the adult rat using a commercially available device. We developed a novel and clinically relevant closed-head injury (CHI) model of both single and multiple concussions in the adult rat using a controlled cortical impact (CCI) device...
October 20, 2016: Journal of Neurotrauma
Carolina Souza Neves da Costa, Sandra L Saavedra, Nelci Adriana Cicuto Ferreira Rocha, Marjorie H Woollacott
BACKGROUND: External support has been viewed as an important biomechanical constraint for children with deficits in postural control. Nonlinear analysis of head stability is necessary to confirm benefits of interaction between external trunk support and level of trunk control. OBJECTIVE: To compare the effect of biomechanical constraints (trunk support) on neural control of head stability during development of trunk control. DESIGN: Quasi-experimental repeated measure study...
October 6, 2016: Physical Therapy
Rebecca M Stanley, Rachel A Jones, Dylan P Cliff, Stewart G Trost, Donna Berthelsen, Jo Salmon, Marijka Batterham, Simon Eckermann, John J Reilly, Ngiare Brown, Karen J Mickle, Steven J Howard, Trina Hinkley, Xanne Janssen, Paul Chandler, Penny Cross, Fay Gowers, Anthony D Okely
BACKGROUND: Participation in regular physical activity (PA) during the early years helps children achieve healthy body weight and can substantially improve motor development, bone health, psychosocial health and cognitive development. Despite common assumptions that young children are naturally active, evidence shows that they are insufficiently active for health and developmental benefits. Exploring strategies to increase physical activity in young children is a public health and research priority...
October 19, 2016: BMC Public Health
Kai Ren, Xiao-Ming Gong, Rong Zhang, Xiu-Hui Chen
OBJECTIVE: To study the effects of virtual reality (VR) training on the gross motor function of the lower limb and the fine motor function of the upper limb in children with spastic diplegia cerebral palsy. METHODS: Thirty-five children with spastic diplegia cerebral palsy were randomly assigned to VR training group (n=19) and conventional training group (n=16). The conventional training group received conventional physical therapy and occupational therapy for three months...
October 2016: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
Huan He, Nino Paichadze, Adnan A Hyder, David Bishai
BACKGROUND: The relationship between economic development and road safety at sub-national level has not been well established. This study aims to assess the relationships between economic growth (measured by gross regional product (GRP)) and road traffic fatalities (RTFs) and crash fatality ratio (CFR) at sub-national level in Russia. METHODS: We used published secondary data on annual RTFs and CFR obtained from the traffic police and socioeconomic development indicators from the statistics department for each Russian federal region (referred to in Russia as "subject") for 2004-2011...
December 2015: Injury Epidemiology
An De Meester, David Stodden, Ali Brian, Larissa True, Greet Cardon, Isabel Tallir, Leen Haerens
BACKGROUND: Positive associations between motor competence and physical activity have been identified by means of variable-centered analyses. To expand the understanding of these associations, this study used a person-centered approach to investigate whether different combinations (i.e., profiles) of actual and perceived motor competence exist (aim 1); and to examine differences in physical activity levels (aim 2) and weight status (aim 3) among children with different motor competence-based profiles...
2016: PloS One
Sanjay Chougule, John Dabis, Aviva Petrie, Karen Daly, Yael Gelfer
BACKGROUND: Reimer's migration percentage (MP) is the most established radiographic risk factor for hip migration in cerebral palsy (CP), and it assists surgical decision-making. The head-shaft angle (HSA) measures the valgus of the head and neck in relation to the shaft and may also be a useful predictor of hip migration at a young age. This study first defined normal values and investigated whether the head-shaft angle (HSA) is a continuous risk factor for hip migration in CP. METHODS: Three hundred and fifty AP pelvic radiographs of 100 consecutive children comprising the hip surveillance programme in our region were analysed for MP and HSA...
October 12, 2016: Journal of Children's Orthopaedics
Lisa M Barnett, Jo Salmon, Kylie D Hesketh
BACKGROUND: Almost half of young children do not achieve minimum recommendations of 60 daily minutes in physical activity. Physical activity is potentially an important determinant of the development of motor competence in children. This study is one of very few longitudinal studies in this area and the first to investigate early childhood physical activity as a predictor of subsequent motor skill competence. METHODS: Children were assessed as part of the Melbourne InFANT Program longitudinal cohort study at 19 months, 3...
October 10, 2016: BMC Public Health
Michal Elboim-Gabyzon, Osnat Atun-Einy, Insaf Khoury-Assaf
PURPOSE: To review the literature on the existent evidence considering the use of power wheel chair (PWC) for children with DMD who can still walk independently. METHODS: A systematic literature search was conducted through nine databases by the three authors independently. Both quantitative and qualitative research designs were considered for inclusion. Studies were included only if the study population consisted of ambulatory children diagnosed with DMD. Data extraction was on participant characteristics, level of walking and on outcomes in term of impairment, function and participation domains (ICF, World Health Organization, 2001) in accordance to a structured diagram by the three authors independently...
October 9, 2016: Disability and Rehabilitation
Jeremy S Francis, Ireneusz Wojtas, Vladimir Markov, Steven J Gray, Thomas J McCown, R Jude Samulski, Larissa T Bilaniuk, Dah-Jyuu Wang, Darryl C De Vivo, Christopher G Janson, Paola Leone
Breakdown of neuro-glial N-acetyl-aspartate (NAA) metabolism results in the failure of developmental myelination, manifest in the congenital pediatric leukodystrophy Canavan disease caused by mutations to the sole NAA catabolizing enzyme aspartoacylase. Canavan disease is a major point of focus for efforts to define NAA function, with available evidence suggesting NAA serves as an acetyl donor for fatty acid synthesis during myelination. Elevated NAA is a diagnostic hallmark of Canavan disease, which contrasts with a broad spectrum of alternative neurodegenerative contexts in which levels of NAA are inversely proportional to pathological progression...
October 4, 2016: Neurobiology of Disease
Helena Mäenpää, Ilona Autti-Rämö, Tarja Varho, Wivi Forsten, Leena Haataja
AIM: To develop a national consensus on outcome measures that define functional ability in children with cerebral palsy (CP) according to the International Classification of Functioning, Disability and Health (ICF) framework. METHOD: The project started in 2008 in neuropaediatric units of two university hospitals and one outpatient clinic. Each professional group selected representatives to be knowledge brokers for their own specialty. Based on the evidence, expert opinion, and the ICF framework, multiprofessional teams selected the most valid measures used in clinical practice (2009-2010)...
October 7, 2016: Developmental Medicine and Child Neurology
C Hsiao, L Richter, T Makusha, B Matafwali, A van Heerden, M Mabaso
BACKGROUND: There are few readily available, relatively easy to use and culturally adaptable developmental assessment tools for young children in southern Africa. The overarching aim of this study is to test the psychometric properties, contextual appropriateness and cut-off scores across 21 age groups of the Ages and Stages Questionnaire Third Edition (Squires & Bricker, ) among a group of typically developing children in South Africa and Zambia through a combination of both caregiver-report and direct observations, and to compare children's performance across sociodemographic variables...
October 5, 2016: Child: Care, Health and Development
Ryan Burns, Tim Brusseau, James Hannon
Motor skills are needed for physical development and may be linked to health-related fitness and physical activity levels. No studies have examined the relationships among these constructs in large samples of disadvantaged children from low-income families using the Test for Gross Motor Development-3rd Edition (TGMD-3). The purpose of this study was to examine the multivariate associations among health-related fitness, physical activity, and motor skills assessed using the TGMD-3. Participants included 1460 school-aged children (730 boys, 730 girls; M age = 8...
October 4, 2016: Perceptual and Motor Skills
Sudhir Adhikari, Kalipatnam Seshagiri Rao
BACKGROUND: Perinatal asphyxia with hypoxic ischemic encephalopathy (HIE) causes significant mortality and morbidity in developing countries. There is limited information about long term neurodevelopmental outcome of infants with neonatal encephalopathy. METHODS: Term infants with the diagnosis of perinatal asphyxia were followed up in neurodevelopmental clinics of Manipal Teaching hospital, Nepal. Study design was prospective mixed longitudinal study. Prematurity, major congenital malformations, other intracranial pathology, birth weight <2500g and chromosomal abnormalities were excluded...
September 30, 2016: Brain & Development
Krista J Spiller, Clark R Restrepo, Tahiyana Khan, Anna M Stieber, Linda K Kwong, John Q Trojanowski, Virginia M-Y Lee
In order to treat progressive paralysis in ALS patients, it is critical to develop a mouse that closely models human ALS in both pathology and also in the timing of these events. We have recently generated new TDP-43 bigenic mice (called rNLS8) with doxycycline (Dox)-suppressible expression of human TDP-43 (hTDP-43) harboring a defective nuclear localization signal (hTDP-43∆NLS) under the control of the NEFH promoter. Our previous studies characterized the pathology and disease course in young rNLS8 mice following induction of neuronal hTDP-43ΔNLS...
September 29, 2016: Acta Neuropathologica Communications
Dattaraj Paramanand Sawarkar, Satish Varma, Pankaj Kumar Singh, Ramesh Doddamani, Amandeep Jagdevan, Bhawani Shanker Sharma
INTRODUCTION: Cerebral venous sinus thrombosis (CVST) is a rare condition with the potential to cause severe morbidity and mortality. CVST can also occur after vestibular schwannoma (VS) surgery with the thrombosis of transverse and sigmoid sinus. However, there is not a single report of superior sagittal sinus (SSS) thrombosis after VS surgery reported in the literature. CASE REPORT: A 45-year-old lady presented to our centre with large left sided solid cystic VS...
September 26, 2016: World Neurosurgery
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