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https://www.readbyqxmd.com/read/29112069/neuropsychological-performance-in-african-children-with-hiv-enrolled-in-a-multi-site-anti-retroviral-clinical-trial
#1
Michael J Boivin, Linda Barlow-Mosha, Miriam Chernoff, Barbara Laughton, Bonnie Zimmer, Celeste Joyce, Mutsa Bwakura-Dangarembizi, Mmule Ratswana, Nasreen Abrahams, Lee Fairlie, Hermien Gous, Portia Kamthunzi, Katie McCarthy, Itziar Familiar-Lopez, Patrick Jean-Phillippe, Joan Coetzee, Avy Violari, Mark Cotton, Paul Palumbo
OBJECTIVE & DESIGN: Children with HIV infection (HIV+) are at neuropsychological risk, but few studies have evaluated this at multiple sites in low and middle income countries (LMICs). We compared neuropsychological outcomes at enrollment (>5 yrs age) among HIV+, HIV-uninfected perinatally-exposed (HEU), and HIV unexposed (HU) children from 4 sub-Saharan countries. METHODS: IMPAACT P1060 compared Nevirapine (NVP) versus Lopinavir/Ritonavir (LPVr)-based ART in HIV-infected children 6 to 35 months of age...
November 2, 2017: AIDS
https://www.readbyqxmd.com/read/29093172/a-computational-analysis-of-signal-fidelity-in-the-rostral-nucleus-of-the-solitary-tract
#2
Alison Boxwell, David Terman, Marion Frank, Yuchio Yanagawa, Joseph B Travers
Neurons in the rostral nucleus of the solitary tract (rNST) convey taste information to both local circuits and pathways destined for forebrain structures. This nucleus is more than a simple relay, however, since rNST neurons differ in response rates and tuning curves relative to primary afferent fibers. To systematically study the impact of convergence and inhibition on firing frequency and breadth of tuning (BOT) in rNST, we constructed a mathematical model of its two major cell types: projection neurons and inhibitory neurons...
November 1, 2017: Journal of Neurophysiology
https://www.readbyqxmd.com/read/28807191/cognitive-and-motor-performance-in-congolese-children-with-konzo-during-4-years-of-follow-up-a-longitudinal-analysis
#3
Michael J Boivin, Daniel Okitundu, Bumoko Makila-Mabe, Marie-Therese Sombo, Dieudonne Mumba, Alla Sikorskii, Banea Mayambu, Desire Tshala-Katumbay
BACKGROUND: Konzo is an irreversible upper-motor neuron disorder affecting children dependent on bitter cassava for food. The neurocognitive ability of children with konzo over time has yet to be fully documented. METHODS: We did a longitudinal study in a konzo outbreak zone continuously affected by konzo since 1990, in the district of Kahemba, southern Bandundu Province, Congo. We enrolled children with a record of neurological diagnosis of konzo in Kahemba town...
September 2017: Lancet Global Health
https://www.readbyqxmd.com/read/28761201/the-impact-of-methylphenidate-on-motor-performance-in-children-with-both-attention-deficit-hyperactivity-disorder-and-developmental-coordination-disorder-a-randomized-double-blind-crossover-clinical-trial
#4
Robabeh Soleimani, Maryam Kousha, Homa Zarrabi, Seyede Mahnaz Tavafzadeh-Haghi, Mir Mohammad Jalali
BACKGROUND: Children with attention deficit hyperactivity disorder/developmental coordination disorder (ADHD/DCD) suffer from problems associated with gross and fine motor skills. There is no effective pharmacological therapy for such patients. We aimed to assess the impact of methylphenidate (MPH) on motor performance of children with ADHD/DCD. METHODS: In this double-blind placebo-controlled, 17 children (12 boys) with ADHD/DCD with a mean age of 7 years 6 months were recruited in Shafa Hospital, Rasht, Iran...
July 2017: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/28665697/feasibility-stability-and-validity-of-the-four-square-step-test-in-typically-developed-children-and-children-with-brain-damage
#5
Gil Leizerowitz, Michal Katz-Leurer
PURPOSE: To assess feasibility, test-retest reliability and validity of the Four Square Step Test (FSST) in typically developed children (TD), and children with cerebral palsy (CP) and acquired brain injury (ABI). METHODS: 30 TD children, 20 with CP and 12 with ABI participated in the study. The FSST while sitting and standing, the Timed Up and Go (TUG) and the balance subtest of the Bruininks-Oseretsky Test (BOT-2) were assessed. Each child attempted the FSST twice within 1 week...
2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28551430/exercise-training-improves-physical-function-and-fitness-in-long-term-paediatric-brain-tumour-survivors-treated-with-cranial-irradiation
#6
P J Piscione, E Bouffet, B Timmons, K S Courneya, D Tetzlaff, J E Schneiderman, C B de Medeiros, U Bartels, D J Mabbott
AIMS: We examined the efficacy of exercise training for improving physical functioning and cardiopulmonary fitness in survivors of paediatric brain tumours (BTs) treated with cranial irradiation. METHODS: We conducted a controlled clinical trial with crossover of exercise training versus no training in the community in either a group or combined group/home setting. A volunteer sample of 28 children treated with cranial irradiation for brain tumours completed training (mean age = 11...
July 2017: European Journal of Cancer
https://www.readbyqxmd.com/read/28506451/motor-skill-development-in-low-income-at-risk-preschoolers-a-community-based-longitudinal-intervention-study
#7
Laura L Bellows, Patricia L Davies, Jimikaye B Courtney, William J Gavin, Susan L Johnson, Richard E Boles
OBJECTIVES: This study aimed to: (1) determine the status of fundamental movement skill (FMS) performance in low-income, at-risk preschoolers; and (2) evaluate the impact of the Food Friends Get Movin' with Mighty Moves (MM) program on improving children's FMS at two-year follow-up. DESIGN: Longitudinal, quasi-experimental study with matched controls. METHODS: The Colorado LEAP study was conducted in four Head Start/preschools (two intervention, two control) serving children aged 3-5 years...
April 26, 2017: Journal of Science and Medicine in Sport
https://www.readbyqxmd.com/read/28371585/validity-of-field-assessments-to-predict-peak-muscle-power-in-preschoolers
#8
Sara King-Dowling, Nicole A Proudfoot, John Cairney, Brian W Timmons
Field-based fitness assessments are time- and cost-efficient. However, no studies to date have reported the predictive value of field-based musculoskeletal fitness assessments in preschoolers. The purpose of this study was to determine the validity of 2 field assessments to predict peak muscle power in preschool-aged children. Four-hundred and nineteen 3- to 5-year olds participated (208 girls, 211 boys; mean age: 4.5 ± 0.9 years). Peak power (PP) was evaluated using a modified 10-s Wingate protocol as the criterion standard...
April 3, 2017: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/28254639/psychometric-and-clinimetric-properties-of-the-melbourne-assessment-2-in-children-with-cerebral-palsy
#9
Tien-Ni Wang, Kai-Jie Liang, Yi-Chia Liu, Jeng-Yi Shieh, Hao-Ling Chen
OBJECTIVE: To examine the psychometric and clinimetric properties of the Melbourne Assessment 2 (MA2), an outcome measurement that is increasingly used in clinical studies. DESIGN: Psychometric and clinimetric study. SETTING: Community. PARTICIPANTS: Seventeen children with cerebral palsy (CP) from 5 to 12 years were recruited for the estimation of the test-retest reliability and minimal detectable change (MDC). Thirty-five children with CP were recruited to receive an 8-week intensive neurorehabilitation intervention to estimate the validity, responsiveness, and minimal clinically important difference (MCID)...
September 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28218875/balance-and-coordination-capacities-of-male-children-and-adolescents-with-intellectual-disability
#10
Ken Pitetti, Ruth Ann Miller, Michael Loovis
Children and adolescents with intellectual disability (ID) exhibit a mixture of cognitive, motor, and psychosocial limitation. Identifying specific inadequacies in motor proficiency in youth with ID would improve therapeutic management to enhance functional capacity and health-related physical activity. The purpose of this study was to initiate descriptive data collection of gross motor skills of youth with ID and compare those skills with competency norms. The Bruininks-Oseretsky Test of Motor Proficiency (BOT-2) was used to measure 6 items for balance (BAL), 5 items for upper limb coordination (ULC), and 6 items for bilateral coordination (BLC) of 123 males (ages 8-18) with ID but without Down syndrome...
January 2017: Adapted Physical Activity Quarterly: APAQ
https://www.readbyqxmd.com/read/28154445/associating-physical-activity-levels-with-motor-performance-and-physical-function-in-childhood-survivors-of-acute-lymphoblastic-leukemia
#11
Stanley H Hung, Anne Rankin, Naznin Virji-Babul, Sheila Pritchard, Christopher Fryer, Kristin L Campbell
Purpose: This cross-sectional, observational study investigated whether physical activity (PA) levels are associated with motor performance and physical function in children after treatment for acute lymphoblastic leukemia (ALL). Method: Participants aged 8-13 years who had completed treatment for ALL (3-36 months post-treatment) were tested at their oncology long-term follow-up appointment at the British Columbia Children's Hospital. PA level was measured using the Physical Activity Questionnaire for Older Children (PAQ-C)...
2017: Physiotherapy Canada. Physiothérapie Canada
https://www.readbyqxmd.com/read/28139029/vincristine-induced-peripheral-neuropathy-in-survivors-of-childhood-acute-lymphoblastic-leukaemia
#12
Chee Geap Tay, Vanessa Wan Mun Lee, Lai Choo Ong, Khean Jin Goh, Hany Ariffin, Choong Yi Fong
BACKGROUND: Vincristine, an essential component of childhood acute lymphoblastic leukaemia (ALL) therapeutic protocols, is associated with dose-dependent neurotoxicity, but its long-term morbidity in treated children has not been clearly elucidated. The aim of this study is to determine the prevalence of vincristine-induced peripheral neuropathy (VIPN) among Malaysian childhood ALL survivors and its impact on motor function and quality of life. PROCEDURE: Survivors of childhood ALL aged 4-18 years who had completed chemotherapy for 2 years or more were evaluated for VIPN using both the clinical Total Neuropathy Score (cTNS) and nerve conduction studies...
August 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/27869410/the-effect-of-strength-training-based-on-process-approach-intervention-on-balance-of-children-with-developmental-coordination-disorder
#13
Hasan Kordi, Mehdi Sohrabi, Alireza Saberi Kakhki, Seyed R Attarzadeh Hossini
INTRODUCTION: Balance is one of the main problems of children with developmental coordination disorder (DCD). According to process-oriented approach, besides strength training, neuromuscular adaptations can improve balance. OBJETIVE: To evaluate the effects of strength training on improving static and dynamic balance in DCD children. METHODS AND POPULATION: Children between 7 to 9 years old in Tehran participated in the study through randomized controlled trial design...
December 1, 2016: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/27832925/ecological-validity-of-the-german-bruininks-oseretsky-test-of-motor-proficiency-2nd-edition
#14
Sabine Vinçon, Dido Green, Rainer Blank, Ekkehart Jenetzky
The diagnosis of Developmental Coordination Disorder (DCD) is based on poor motor coordination in the absence of other neurological disorders. In order to identify the presence of movement difficulties, a standardised motor assessment is recommended to determine the extent of movement problems which may contribute to deficits in daily task performance. A German version of the Bruininks-Oseretsky Test of Motor Proficiency, Second Edition (German BOT-2) was recently published. This study aimed to determine the ecological validity of the German BOT-2 by considering the relationship between assessment of fundamental motor skills with the BOT-2 and performance of everyday motor activities as evaluated by parents...
November 7, 2016: Human Movement Science
https://www.readbyqxmd.com/read/27751561/assessing-motor-proficiency-in-young-adults-the-bruininks-oseretsky-test-2-short-form-and-the-mccarron-assessment-of-neuromuscular-development
#15
F McIntyre, H Parker, A Thornton, M Licari, J Piek, D Rigoli, B Hands
Currently, only two motor tests have norms extending into young adulthood - the McCarron Assessment of Neuromuscular Development (MAND, McCarron 1997) and the Bruininks Oseretsky Test of Motor Proficiency-2 (BOT-2, Bruininks & Bruininks, 2005). Research into the motor difficulties in early adulthood and health outcomes has been impeded because there is no agreed gold standard motor test for this group. The purposes of this study were to compare the discrimination accuracy, classification agreement, and predictive values, and gender distribution and prevalence of each test in identifying motor impairment (MI) in relation to DSM-V diagnostic criteria for DCD...
October 14, 2016: Human Movement Science
https://www.readbyqxmd.com/read/27749751/unilateral-hearing-loss-is-associated-with-impaired-balance-in-children-a-pilot-study
#16
Nikolaus E Wolter, Sharon L Cushing, Luis D Vilchez-Madrigal, Adrian L James, Jennifer Campos, Blake C Papsin, Karen A Gordon
OBJECTIVE: To determine if children with unilateral sensorineural hearing loss (UHL) demonstrate impaired balance compared with their normal hearing (NH) peers. STUDY DESIGN: Prospective, case-control study. METHODS: Balance was assessed in14 UHL and 14 NH children using the Bruininks-Oseretsky Test-2 (BOT-2) and time to fall (TTF) in an immersive, virtual-reality laboratory. Postural control was quantified by center of pressure (COP) using force plates...
December 2016: Otology & Neurotology
https://www.readbyqxmd.com/read/27740896/association-between-body-mass-index-and-motor-competence-in-santal-children-of-purulia-district-india
#17
Sutanu Dutta Chowdhury, Brian H Wrotniak, Tusharkanti Ghosh
The purpose of this study was to evaluate the relationship between body mass index and motor competence in Santal children 5-12 years old. A total of 816 Santal children were studied. Children's adiposity status was assessed by body mass index (BMI) for age z-score based on World Health Organization reference data. Motor competence was measured using the Bruininks-Oseretsky Test of Motor Competence (BOT-2). There was no significant difference in mean BMI z-score between Santal boys (0.13 ± 0.07) and girls (-0...
May 2017: Journal of Motor Behavior
https://www.readbyqxmd.com/read/27439995/gross-motor-performance-in-children-prenatally-exposed-to-alcohol-and-living-in-remote-australia
#18
Barbara R Lucas, Jane Latimer, Robyn Doney, Rochelle E Watkins, Tracey W Tsang, Genevieve Hawkes, James P Fitzpatrick, June Oscar, Maureen Carter, Elizabeth J Elliott
AIM: This study aimed to determine the gross motor (GM) performance of Aboriginal children living in remote Australia. The relationship between GM skills, prenatal alcohol exposure (PAE) and fetal alcohol spectrum disorders (FASD) was explored. METHODS: A population-based observation study was conducted in 2011 to assess motor performance in children living in the Fitzroy Valley, Western Australia, using the Bruininks-Oseretsky Test of Motor Proficiency (BOT-2)...
August 2016: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/27423302/the-effect-of-exergames-on-functional-strength-anaerobic-fitness-balance-and-agility-in-children-with-and-without-motor-coordination-difficulties-living-in-low-income-communities
#19
Bouwien C M Smits-Engelsman, L Dorothee Jelsma, Gillian D Ferguson
Children with Developmental Coordination Disorder (DCD) are physically less active, preferring more sedentary behavior and are at risk of developing health problems or becoming overweight. 18 children (age 6-10years) with lower levels of motor coordination attending a primary school in a low-income community in South Africa (score on Movement Assessment Battery for Children Second edition equal to or below the 5th percentile) were selected to participate in the study and were age-matched with typically developing peers (TD)...
October 2017: Human Movement Science
https://www.readbyqxmd.com/read/27357876/fine-motor-activities-program-to-promote-fine-motor-skills-in-a-case-study-of-down-s-syndrome
#20
Suchitporn Lersilp, Supawadee Putthinoi, Kewalin Panyo
Children with Down's syndrome have developmental delays, particularly regarding cognitive and motor development. Fine motor skill problems are related to motor development. They have impact on occupational performances in school-age children with Down's syndrome because they relate to participation in school activities, such as grasping, writing, and carrying out self-care duties. This study aimed to develop a fine motor activities program and to examine the efficiency of the program that promoted fine motor skills in a case study of Down's syndrome...
2016: Global Journal of Health Science
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