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https://www.readbyqxmd.com/read/28821101/cholesteric-film-of-cu-ii-doped-cellulose-nanocrystals-for-colorimetric-sensing-of-ammonia-gas
#1
Shidong Dai, Nana Prempeh, Dagang Liu, Yimin Fan, Mingyue Gu, Yu Chang
With the increasing demand of environmental monitoring for toxic and odorous ammonia gas it is desired to develop specific green, cost-effective and in situ passive colorimetric alternatives to current complex instrumentations. In this work, we designed an ammonia gas sensor based on cholesteric liquid crystal films of copper(II)-doped cellulose nanocrystals (CNCCu(II)) whose structure, optical and sensing properties were investigated. The hybrid films using the low doping Cu(II) as a color-tuning agent inherited the chiral nematic signature and optical activity of CNCs, suggesting a strong chelation between copper ions and negatively charged CNCs...
October 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28820952/adult-intelligence-the-construct-and-the-criterion-problem
#2
Phillip L Ackerman
Over 100 years have passed since Binet and Simon proposed scales for assessment of intelligence of children to predict academic success and failure. The extension of these assessments to adults largely resulted from efforts of psychologists to provide insights for military selection in World War I. At the time, relatively little thought was given to how adult intelligence might differ from child and adolescent intelligence. Traditional approaches for assessing adult intelligence have largely survived. However, there is little reference to adult intellectual functioning outside of laboratory-based tasks and clinical assessments of pathology...
August 1, 2017: Perspectives on Psychological Science: a Journal of the Association for Psychological Science
https://www.readbyqxmd.com/read/28820253/bioinorganic-chemistry-of-parkinson-s-disease-affinity-and-structural-features-of-cu-i-binding-to-the-full-length-%C3%AE-synuclein-protein
#3
Marco C Miotto, Mayra D Pavese, Liliana Quintanar, Markus Zweckstetter, Christian Griesinger, Claudio O Fernández
Alterations in the levels of copper in brain tissue and formation of α-synuclein (αS)-copper complexes might play a key role in the amyloid aggregation of αS and the onset of Parkinson's disease (PD). Recently, we demonstrated that formation of the high-affinity Cu(I) complex with the N-terminally acetylated form of the protein αS substantially increases and stabilizes local conformations with α-helical secondary structure and restricted motility. In this work, we performed a detailed NMR-based structural characterization of the Cu(I) complexes with the full-length acetylated form of its homologue β-synuclein (βS), which is colocalized with αS in vivo and can bind copper ions...
August 18, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28820084/the-effectiveness-of-healthy-meals-at-work-on-reaction-time-mood-and-dietary-intake-a-randomised-cross-over-study-in-daytime-and-shift-workers-at-an-university-hospital
#4
Eva Leedo, Anne Marie Beck, Arne Astrup, Anne D Lassen
Our dietary habits affect both cognitive performance and mood. The aim of the study was to examine the effect of increased availability of healthy meals and water at work on healthcare staff. The study used an 8-week randomised cross-over design. A total of sixty physicians, nurses and nursing assistants, including sixteen working on shifts, were recruited. The participants received a self-selected keyhole-labelled (Nordic nutrition label) lunch, snack and bottled water during each shift throughout the intervention period...
July 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28819300/yebc-a-putative-transcriptional-factor-involved-in-the-regulation-of-the-proteolytic-system-of-lactobacillus
#5
Lucía Brown, Josefina M Villegas, Mariano Elean, Silvina Fadda, Fernanda Mozzi, Lucila Saavedra, Elvira M Hebert
The proteolytic system of Lactobacillus plays an essential role in bacterial growth, contributes to the flavor development of fermented products, and can release bioactive health-beneficial peptides during milk fermentation. In this work, a genomic analysis of all genes involved in the proteolytic system of L. delbrueckii subsp. lactis CRL 581 was performed. Genes encoding the cell envelope-associated proteinase, two peptide transport systems, and sixteen peptidases were identified. The influence of the peptide supply on the transcription of 23 genes involved in the proteolytic system of L...
August 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28817503/interprovider-communication-using-a-scheduled-provider-alert-response-communication-system-in-3-inpatient-neurology-units
#6
James E Siegler, Dan Finegan, Scott E Kasner, Raymond S Price
BACKGROUND: Nonemergent communications between nursing staff and residents often occur randomly throughout the workday at teaching institutions, resulting in inefficiency and interruptions of scheduled resident educational conferences or periods of overnight rest. OBJECTIVE: The aim of this study was to determine whether a quality improvement communication strategy can reduce interruptive notifications during scheduled resident didactic sessions. METHODS: We conducted a prospective, mixed-methods trial of a communication strategy between nurses and residents in 3 neurology units of an academic institution...
August 16, 2017: Journal of Neuroscience Nursing: Journal of the American Association of Neuroscience Nurses
https://www.readbyqxmd.com/read/28816629/a-cascade-model-of-mentorship-for-frontline-health-workers-in-rural-health-facilities-in-eastern-uganda-processes-achievements-and-lessons
#7
Judith Ajeani, Richard Mangwi Ayiasi, Moses Tetui, Elizabeth Ekirapa-Kiracho, Gertrude Namazzi, Ronald Muhumuza Kananura, Suzanne Namusoke Kiwanuka, Jolly Beyeza-Kashesya
BACKGROUND: There is increasing demand for trainers to shift from traditional didactic training to innovative approaches that are more results-oriented. Mentorship is one such approach that could bridge the clinical knowledge gap among health workers. OBJECTIVES: This paper describes the experiences of an attempt to improve health-worker performance in maternal and newborn health in three rural districts through a mentoring process using the cascade model. The paper further highlights achievements and lessons learnt during implementation of the cascade model...
August 2017: Global Health Action
https://www.readbyqxmd.com/read/28816148/prompt-gamma-imaging-for-in%C3%A2-vivo-range-verification-of-pencil-beam-scanning-proton-therapy
#8
Yunhe Xie, El Hassane Bentefour, Guillaume Janssens, Julien Smeets, François Vander Stappen, Lucian Hotoiu, Lingshu Yin, Derek Dolney, Stephen Avery, Fionnbarr O'Grady, Damien Prieels, James McDonough, Timothy D Solberg, Robert A Lustig, Alexander Lin, Boon-Keng K Teo
PURPOSE: To report the first clinical results and value assessment of prompt gamma imaging for in vivo proton range verification in pencil beam scanning mode. METHODS AND MATERIALS: A stand-alone, trolley-mounted, prototype prompt gamma camera utilizing a knife-edge slit collimator design was used to record the prompt gamma signal emitted along the proton tracks during delivery of proton therapy for a brain cancer patient. The recorded prompt gamma depth detection profiles of individual pencil beam spots were compared with the expected profiles simulated from the treatment plan...
September 1, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28815762/examining-the-social-construction-of-surveillance-a-critical-issue-for-health-visitors-and-public-health-nurses-working-with-mothers-and-children
#9
Megan Aston, Sue Peckover
AIMS AND OBJECTIVES: In this paper we will critically examine surveillance practices of health visitors (HV) in the UK and public health nurses (PHNs) in Canada. BACKGROUND: The practice and meaning of surveillance shifts and changes depending on the context and intent of relationships between mothers and HVs or PHNs. DESIGN: We present the context and practice of HVs in the UK and PHNs in Canada and provide a comprehensive literature review regarding surveillance of mothers within public health systems...
August 17, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28815603/registration-of-phase-contrast-images-in-propagation-based-x-ray-phase-tomography
#10
L Weber, A Hänsch, U Wolfram, A Pacureanu, P Cloetens, F Peyrin, S Rit, M Langer
X-ray phase tomography aims at reconstructing the 3D electron density distribution of an object. It offers enhanced sensitivity compared to attenuation-based X-ray absorption tomography. In propagation-based methods, phase contrast is achieved by letting the beam propagate after interaction with the object. The phase shift is then retrieved at each projection angle, and subsequently used in tomographic reconstruction to obtain the refractive index decrement distribution, which is proportional to the electron density...
August 16, 2017: Journal of Microscopy
https://www.readbyqxmd.com/read/28815586/differential-interference-contrast-photothermal-microscopy-in-nanospace-impacts-of-systematic-parameters
#11
M Liu
Differential interference contrast-photothermal microscopy (DIC-PTM), as a promising tool for trace analysis of nonfluorescent compounds, suffered low sensitivity in nanospace especially for aqueous samples, due to the poor thermophysical property of water and the unoptimised configuration. To improve its performance, a five-layer DIC-PTM model is built and influences of different parameters on the photothermal signal are investigated. The initial phase shift φ0 between two branches of the probe beam is found to be a key factor determining the detection sensitivity and response linearity: at a large φ0 (≤π/2) both a high sensitivity and a good linearity can be achieved, while a high signal-to-noise ratio occurs at a small φ0 ...
August 16, 2017: Journal of Microscopy
https://www.readbyqxmd.com/read/28815423/backbone-and-side-chain-1-h-15-n-and-13-c-resonance-assignments-of-a-novel-staphylococcal-inhibitor-of-myeloperoxidase
#12
Nicoleta T Ploscariu, Alvaro I Herrera, Srinivas Jayanthi, Thallapuranam K Suresh Kumar, Brian V Geisbrecht, Om Prakash
The bacterium Staphylococcus aureus produces an array of anti-inflammatory molecules that prevent the innate immune system from recognizing it as a pathogen and clearing it from the host. In the acute phase of inflammation, our immune system relies on neutrophils to clear invading bacteria. Recently, novel classes of secreted proteins from S. aureus, including the Extracellular Adherence Protein (EAP) family (Stapels et al., Proc Natl Acad Sci USA 111:13187-13192, 2014) and the Staphylococcal Peroxidase Inhibitor (SPIN), (unpublished work) have been identified as highly selective inhibitors acting on Neutrophil Serine Proteases (NSPs) and myeloperoxidase (MPO) respectively...
August 16, 2017: Biomolecular NMR Assignments
https://www.readbyqxmd.com/read/28814999/centralization-of-liver-cancer-surgery-and-impact-on-multidisciplinary-teams-working-on-stage-iv-colorectal-cancer
#13
REVIEW
Elroy Patrick Weledji
Surgical resection is the most effective treatment approach for colorectal liver metastases but only a minority of patients is suitable for upfront surgery. The treatment strategies of stage IV colorectal cancer have shifted towards a continuum of care in which medical and surgical treatment combinations are tailored to the clinical setting of the individual patient. The optimization of treatment through appropriate decision-making and multimodal therapy for stage IV colorectal cancer require a joint multidisciplinary meeting in a centralized liver cancer unit...
June 14, 2017: Oncology Reviews
https://www.readbyqxmd.com/read/28814635/perception-of-the-dynamic-visual-vertical-during-sinusoidal-linear-motion
#14
Antonella Pomante, Luc P J Selen, W Pieter Medendorp
The vestibular system provides information for spatial orientation. However, this information is ambiguous: because the otoliths sense the gravito-inertial force, they cannot distinguish gravitational and inertial components. As a consequence, prolonged linear acceleration of the head can be interpreted as tilt, referred to as the somatogravic effect. Previous modeling work suggests that the brain disambiguates the otolith signal according to the rules of Bayesian inference, combining noisy canal cues with the a priori assumption that prolonged linear accelerations are unlikely...
August 16, 2017: Journal of Neurophysiology
https://www.readbyqxmd.com/read/28814584/examining-self-reported-and-biological-stress-and-near-misses-among-emergency-medicine-residents-a-single-centre-cross-sectional-assessment-in-the-usa
#15
Bengt B Arnetz, Philip Lewalski, Judy Arnetz, Karen Breejen, Karin Przyklenk
OBJECTIVES: To examine the relationship between perceived and biological stress and near misses among Emergency Medicine residents. DESIGN: Self-rated stress and stress biomarkers were assessed in residents in Emergency Medicine before and after a day shift. The supervising physicians and residents reported numbers of near misses. SETTING: The study took place in the Emergency Department of a large trauma 1 centre, located in Detroit, USA...
August 15, 2017: BMJ Open
https://www.readbyqxmd.com/read/28813791/codification-mechanisms-of-wrist-position-sense
#16
Francesca Marini, Sara Contu, Pietro Morasso, Lorenzo Masia, Jacopo Zenzeri
Proprioceptive signals from cutaneous, joint, tendon and muscle receptors create the basis for bodily perception and are known to be essential for motor control. However, which are the mechanisms underlying the proprioceptive signals and which are the variables that affect them is still a matter of debate. In particular, what is worth to investigate is, namely, the codification of proprioceptive information related to pointing movements of the wrist towards kinesthetic targets. In this work we asked 10 healthy adults to perform with their wrist a robot-aided proprioceptive matching task, in which the starting position of the matching movements was shifted forward or backward, in order to ascertain to which extent such shifts cause target over/under estimation and how important is movement's length on task performance...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28813589/regulation-of-stability-on-histone-h2a-h2b-dimer-by-h2a-tyr57-phosphorylation
#17
Takuma Sueoka, Gosuke Hayashi, Akimitsu Okamoto
Histone H2A and H2B form a H2A-H2B heterodimer, which is a fundamental unit of nucleosome assembly and disassembly. Several posttranslational modifications change the interface between the H2A-H2B dimer and the H3-H4 tetramer, and regulate nucleosome stability. However, posttranslational modifications associated with the interface between H2A and H2B have not been discussed. In this paper, it is shown that Tyr57 phosphorylation in H2A strongly influences H2A-H2B dimerization. Tyr57-phosphorylated H2A was chemically synthesized and utilized to reconstitute the H2A-H2B dimer and nucleosome as well as canonical H2A...
August 16, 2017: Biochemistry
https://www.readbyqxmd.com/read/28813506/global-and-local-disturbances-interact-to-modify-seagrass-palatability
#18
Rocío Jiménez-Ramos, Luis G Egea, María J Ortega, Ignacio Hernández, Juan J Vergara, Fernando G Brun
Global change, such as warming and ocean acidification, and local anthropogenic disturbances, such as eutrophication, can have profound impacts on marine organisms. However, we are far from being able to predict the outcome of multiple interacting disturbances on seagrass communities. Herbivores are key in determining plant community structure and the transfer of energy up the food web. Global and local disturbances may alter the ecological role of herbivory by modifying leaf palatability (i.e. leaf traits) and consequently, the feeding patterns of herbivores...
2017: PloS One
https://www.readbyqxmd.com/read/28813469/phytoplasma-infection-of-a-tropical-root-crop-triggers-bottom-up-cascades-by-favoring-generalist-over-specialist-herbivores
#19
Kris A G Wyckhuys, Ignazio Graziosi, Dharani Dhar Burra, Abigail Jan Walter
Global interest on plant-microbe-insect interactions is rapidly growing, revealing the multiple ways in which microorganisms mediate plant-herbivore interactions. Phytopathogens regularly alter whole repertoires of plant phenotypic traits, and bring about shifts in key chemical or morphological characteristics of plant hosts. Pathogens can also cause cascading effects on higher trophic levels, and eventually shape entire plant-associated arthropod communities. We tested the hypothesis that a Candidatus Phytoplasma causing cassava witches' broom (CWB) on cassava (Manihot esculenta Grantz) is altering species composition of invasive herbivores and their associated parasitic hymenopterans...
2017: PloS One
https://www.readbyqxmd.com/read/28813238/strategies-for-building-trust-with-the-caregiver-of-a-patient-with-end-stage-dementia
#20
Helen Stanton Chapple
This case describes a patient with advanced dementia and an unrealistic spouse, presenting an apparent dilemma about nutrition for physicians. By eliciting the perspective of the caregiver, the physicians can gain insight and rebuild trust that protects the interests of both the patient and the spouse. Their goal needs to shift from resolving the professional ethical dilemma to affirming the immeasurable contribution of the caregiver, acknowledging her journey, asking for her advice, and enabling the work of making meaning in the time available...
July 1, 2017: AMA Journal of Ethics
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