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https://www.readbyqxmd.com/read/27914094/walking-through-a-virtual-environment-improves-perceived-size-within-and-beyond-the-walked-space
#1
Zachary D Siegel, Jonathan W Kelly
Distances tend to be underperceived in virtual environments (VEs) by up to 50%, whereas distances tend to be perceived accurately in the real world. Previous work has shown that allowing participants to interact with the VE while receiving continual visual feedback can reduce this underperception. Judgments of virtual object size have been used to measure whether this improvement is due to the rescaling of perceived space, but there is disagreement within the literature as to whether judgments of object size benefit from interaction with feedback...
December 2, 2016: Attention, Perception & Psychophysics
https://www.readbyqxmd.com/read/27914016/ms-ms-assisted-design-of-sequence-controlled-synthetic-polymers-for-improved-reading-of-encoded-information
#2
Laurence Charles, Gianni Cavallo, Valérie Monnier, Laurence Oswald, Roza Szweda, Jean-François Lutz
In order to improve their MS/MS sequencing, structure of sequence-controlled synthetic polymers can be optimized based on considerations regarding their fragmentation behavior in collision-induced dissociation conditions, as demonstrated here for two digitally encoded polymer families. In poly(triazole amide)s, the main dissociation route proceeded via cleavage of the amide bond in each monomer, hence allowing the chains to be safely sequenced. However, a competitive cleavage of an ether bond in a tri(ethylene glycol) spacer placed between each coding moiety complicated MS/MS spectra while not bringing new structural information...
December 2, 2016: Journal of the American Society for Mass Spectrometry
https://www.readbyqxmd.com/read/27913966/validating-presupposed-versus-focused-text-information
#3
Murray Singer, Kevin G Solar, Jackie Spear
There is extensive evidence that readers continually validate discourse accuracy and congruence, but that they may also overlook conspicuous text contradictions. Validation may be thwarted when the inaccurate ideas are embedded sentence presuppositions. In four experiments, we examined readers' validation of presupposed ("given") versus new text information. Throughout, a critical concept, such as a truck versus a bus, was introduced early in a narrative. Later, a character stated or thought something about the truck, which therefore matched or mismatched its antecedent...
December 2, 2016: Memory & Cognition
https://www.readbyqxmd.com/read/27913953/neuroinflammation-induced-downregulation-of-hippocampacal-neuregulin-1-erbb4-signaling-in-the-parvalbumin-interneurons-might-contribute-to-cognitive-impairment-in-a-mouse-model-of-sepsis-associated-encephalopathy
#4
Rong Gao, Mu-Huo Ji, Da-Peng Gao, Run-Hua Yang, Shao-Gang Zhang, Jian-Jun Yang, Jin-Chun Shen
Sepsis-associated encephalopathy (SAE) is a common complication associated with poor prognosis in septic patients, but the underlying mechanism remains unclear. We hypothesized that disturbed neuregulin 1 (NRG1)-ErbB4 signaling in the parvalbumin interneurons was involved in sepsis-induced cognitive impairment in a mouse model of SAE. The SAE model was induced by cecal ligation/perforation (CLP). Animals were randomly divided into the following six groups: sham + vehicle group, sham + NRG1 group, CLP + vehicle group, CLP + NRG1 group, CLP + NRG1 + AG1478 (ErbB4 inhibitor) group, and CLP + minocycline group...
December 2, 2016: Inflammation
https://www.readbyqxmd.com/read/27913863/-multifocal-intraocular-lens-miol-surgery-in-young-non-presbyopic-ametropes-reasonable-and-safe
#5
A Frings, J Steinberg, S J Linke, V Druchkiv, T Katz
BACKGROUND: Refractive lens exchange and implantation of a multifocal intraocular lens (MIOL) is mainly advised for ametropes with presbyopia. Non-presbyopic young ametropes who wish spectacle-independence are usually treated with corneal refractive surgery or phakic lenses. OBJECTIVES: This retrospective case series aimed to analyse the refractive and subjective satisfaction outcome after MIOL surgery in both eyes of non-presbyopic ametropes where other treatment options were not possible...
December 2, 2016: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/27913832/general-and-specific-combining-abilities-in-a-maize-zea-mays-l-test-cross-hybrid-panel-relative-importance-of-population-structure-and-genetic-divergence-between-parents
#6
A Larièpe, L Moreau, J Laborde, C Bauland, S Mezmouk, L Décousset, T Mary-Huard, J B Fiévet, A Gallais, P Dubreuil, A Charcosset
General and specific combining abilities of maize hybrids between 288 inbred lines and three tester lines were highly related to population structure and genetic distance inferred from SNP data. Many studies have attempted to provide reliable and quick methods to identify promising parental lines and combinations in hybrid breeding programs. Since the 1950s, maize germplasm has been organized into heterotic groups to facilitate the exploitation of heterosis. Molecular markers have proven efficient tools to address the organization of genetic diversity and the relationship between lines or populations...
December 2, 2016: TAG. Theoretical and Applied Genetics. Theoretische und Angewandte Genetik
https://www.readbyqxmd.com/read/27913619/the-caenorhabditis-elegans-nf2-merlin-molecule-nfm-1-non-autonomously-regulates-neuroblast-migration-and-interacts-genetically-with-the-guidance-cue-slt-1-slit
#7
Matthew P Josephson, Rana Aliani, Megan L Norris, Matthew E Ochs, Mahekta Gujar, Erik A Lundquist
During nervous system development, neurons and their progenitors migrate to their final destinations. In Caenorhabditis elegans, the bilateral Q neuroblasts and their descendants migrate long distances in opposite directions, despite being born in the same posterior region. QR on the right migrates anteriorly and generates the AQR neuron positioned near the head, and QL on the left migrates posteriorly, giving rise to the PQR neuron positioned near the tail. In a screen for genes required for AQR and PQR migration, we identified an allele of nfm-1, which encodes a molecule similar to vertebrate NF2/Merlin, an important tumor suppressor in humans...
December 2, 2016: Genetics
https://www.readbyqxmd.com/read/27913454/the-anti-bat-strategy-of-ultrasound-absorption-the-wings-of-nocturnal-moths-bombycoidea-saturniidae-absorb-more-ultrasound-than-the-wings-of-diurnal-moths-chalcosiinae-zygaenoidea-zygaenidae
#8
Athanasios Ntelezos, Francesco Guarato, James F C Windmill
The selection pressure from echolocating bats has driven the development of a diverse range of anti-bat strategies in insects. For instance, several studies have proposed that the wings of some moths absorb a large portion of the sound energy contained in a bat's ultrasonic cry; as a result, the bat receives a dampened echo, and the moth becomes invisible to the bat. To test the hypothesis that greater exposure to bat predation drives the development of higher ultrasound absorbance, we used a small reverberation chamber to measure the ultrasound absorbance of the wings of nocturnal (Bombycoidea: Saturniidae) and diurnal moths (Chalcosiinae: Zygaenoidea: Zygaenidae)...
December 2, 2016: Biology Open
https://www.readbyqxmd.com/read/27913270/part-1-comparison-of-plasma-ammonia-results-from-seven-different-automated-platforms-in-use-throughout-central-australia
#9
Corey Markus, Michael Metz
INTRODUCTION: The clinical catchment area for the Metabolic service at the Women's and Children's Hospital in Adelaide, South Australia, covers nearly 2.5millionkm(2). Care of children with metabolic disorders in these remote areas is assisted from Adelaide, and at times, using plasma ammonia results from laboratories up to 3000km away. There are seven different platforms measuring plasma ammonia within this vast clinical catchment area. Hence, a correlation study was conducted to examine the relationship between plasma ammonia results from the seven different platforms in use throughout central Australia...
November 29, 2016: Clinical Biochemistry
https://www.readbyqxmd.com/read/27913265/hearing-preservation-during-anterior-petrosectomy-the-cochlear-safety-line
#10
Xiaoming Guo, Halima Tabani, Dylan Griswold, Ali Tayebi Meybodi, Jose Juan Gonzalez Sanchez, Michael T Lawton, Arnau Benet
BACKGROUND: Identification and protection of the cochlea during anterior petrosectomy is key to prevent hearing loss. Currently, there is no optimal method to infer the position of the cochlea in relation to the Kawase quadrangle, therefore damage to the cochlea during anterior petrosectomy remains a substantial risk. OBJECTIVES: To identify and define landmarks available during anterior petrosectomy to locate the cochlea and prevent its damage. METHODS: Kawase approach was simulated in eleven specimens...
November 29, 2016: World Neurosurgery
https://www.readbyqxmd.com/read/27913245/contextual-computing-a-bluetooth-based-approach-for-tracking-healthcare-providers-in-the-emergency-room
#11
Joshua Frisby, Vernon Smith, Stephen Traub, Vimla L Patel
Hospital Emergency Departments (EDs) frequently experience crowding. One of the factors that contributes to this crowding is the "door to doctor time", which is the time from a patient's registration to when the patient is first seen by a physician. This is also one of the Meaningful Use (MU) performance measures that emergency departments report to the Center for Medicare and Medicaid Services (CMS). Current documentation methods for this measure are inaccurate due to the imprecision in manual data collection...
November 29, 2016: Journal of Biomedical Informatics
https://www.readbyqxmd.com/read/27913175/automated-cta-based-measurements-for-planning-support-of-minimally-invasive-aortic-valve-replacement-surgery
#12
Mustafa A Elattar, Floortje van Kesteren, Esther M Wiegerinck, Ed Vanbavel, Jan Baan, Riccardo Cocchieri, Bas de Mol, Nils R Planken, Henk A Marquering
Minimally invasive aortic valve replacement (mini-AVR) procedures are a valuable alternative to conventional open heart surgery. Currently, planning of mini-AVR consists of selection of the intercostal space closest to the sinotubular junction on preoperative computer tomography images. We developed an automated algorithm detecting the sinotubular junction (STJ) and intercostal spaces for finding the optimal incision location. The accuracy of the STJ detection was assessed by comparison with manual delineation by measuring the Euclidean distance between the manually and automatically detected points...
November 29, 2016: Medical Engineering & Physics
https://www.readbyqxmd.com/read/27913165/larger-females-are-choosier-in-the-gray-treefrog-hyla-versicolor
#13
Michael C Kuczynski, Thomas Getty, Eben Gering
Individual variation in female mate choice has important implications for sexual trait evolution and the maintenance of phenotypic diversity. In this study we examined several potential drivers of individual variation in female choosiness for the well-studied, energetically expensive courtship signal of male gray treefrogs, Hyla versicolor. Specifically, we investigated the relationship between female choosiness and other female traits (female body size, physical condition, and age) using a costly choice playback experiment where females traveled different simulated distances to reach attractive mates...
November 29, 2016: Behavioural Processes
https://www.readbyqxmd.com/read/27913017/marine-anthropogenic-litter-on-british-beaches-a-10-year-nationwide-assessment-using-citizen-science-data
#14
S E Nelms, C Coombes, L C Foster, T S Galloway, B J Godley, P K Lindeque, M J Witt
Growing evidence suggests that anthropogenic litter, particularly plastic, represents a highly pervasive and persistent threat to global marine ecosystems. Multinational research is progressing to characterise its sources, distribution and abundance so that interventions aimed at reducing future inputs and clearing extant litter can be developed. Citizen science projects, whereby members of the public gather information, offer a low-cost method of collecting large volumes of data with considerable temporal and spatial coverage...
November 29, 2016: Science of the Total Environment
https://www.readbyqxmd.com/read/27912764/sbrt-for-centrally-localized-nsclc-what-is-too-central
#15
J Roesch, C Panje, F Sterzing, F Mantel, U Nestle, N Andratschke, M Guckenberger
PURPOSE: Current guidelines recommend stereotactic body radiotherapy (SBRT) for stage I non-small-cell lung cancer (NSCLC) in medically inoperable patients. There are excellent outcome and toxicity data for SBRT of peripheral lung tumors. However, the discussion on SBRT for centrally located tumors is controversial. This study evaluated current clinical practice regarding SBRT of centrally located lung tumors, to identify common fractionation schedules and commonly accepted contraindications for SBRT...
December 3, 2016: Radiation Oncology
https://www.readbyqxmd.com/read/27912745/ganoderma-lucidum-beta-1-3-1-6-glucan-as-an-immunomodulator-in-inflammation-induced-by-a-high-cholesterol-diet
#16
Yu-Sheng Wu, Shu-Ying Ho, Fan-Hua Nan, Shiu-Nan Chen
BACKGROUND: Binding of beta 1,3/1,6 glucan of Ganoderma lucidum (G. lucidum) with the receptor results in a series of signal transfers (signalling cascades), which activates the transcription factors for regulating inflammation. Excess cholesterol intake leads to an increase in the distance between fat cells and capillaries, which may cause hypoxia in the fat tissue of obese mice. This hypoxia induces the death of fat cells, resulting in the inflammation of adipose tissue or an increase in the inflammatory gene expression associated with obesity...
December 3, 2016: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/27912731/predicting-the-recurrence-of-noncoding-regulatory-mutations-in-cancer
#17
Woojin Yang, Hyoeun Bang, Kiwon Jang, Min Kyung Sung, Jung Kyoon Choi
BACKGROUND: One of the greatest challenges in cancer genomics is to distinguish driver mutations from passenger mutations. Whereas recurrence is a hallmark of driver mutations, it is difficult to observe recurring noncoding mutations owing to a limited amount of whole-genome sequenced samples. Hence, it is required to develop a method to predict potentially recurrent mutations. RESULTS: In this work, we developed a random forest classifier that predicts regulatory mutations that may recur based on the features of the mutations repeatedly appearing in a given cohort...
December 3, 2016: BMC Bioinformatics
https://www.readbyqxmd.com/read/27912252/impact-of-stretching-on-the-performance-and-injury-risk-of-long-distance-runners
#18
Claire Baxter, Lars R Mc Naughton, Andy Sparks, Lynda Norton, David Bentley
Stretching, either prior to exercise or at the end, or both, is typically carried out by all individuals undertaking sporting activity whether they be elite or recreational athletes. The many forms of stretching available to the athlete, either passive or active, have long been thought to improve performance, decrease injury and generally be advantageous to the athlete. This review examines the current state of the literature and evaluates what athletes can and should do with respect to this controversial topic...
December 2, 2016: Research in Sports Medicine
https://www.readbyqxmd.com/read/27912164/manganese-ii-chloride-alters-behavioral-and-neurochemical-parameters-in-larvae-and-adult-zebrafish
#19
Stefani Altenhofen, Melissa Talita Wiprich, Laura Roesler Nery, Carlos Eduardo Leite, Monica Ryff Moreira Roca Vianna, Carla Denise Bonan
Manganese (Mn) is an essential metal for organisms, but high levels can cause serious neurological damage. The aim of this study was to evaluate the effects of MnCl2 exposure on cognition and exploratory behavior in adult and larval zebrafish and correlate these findings with brain accumulation of Mn, overall brain tyrosine hydroxylase (TH) levels, dopamine (DA) levels, 3,4-dihydroxyphenylacetic acid (DOPAC) levels and cell death markers in the nervous system. Adults exposed to MnCl2 for 4days (0.5, 1.0 and 1...
November 17, 2016: Aquatic Toxicology
https://www.readbyqxmd.com/read/27912151/euclidean-distances-as-measures-of-speaker-similarity-including-identical-twin-pairs-a-forensic-investigation-using-source-and-filter-voice-characteristics
#20
Eugenia San Segundo, Athanasios Tsanas, Pedro Gómez-Vilda
There is a growing consensus that hybrid approaches are necessary for successful speaker characterization in Forensic Speaker Comparison (FSC); hence this study explores the forensic potential of voice features combining source and filter characteristics. The former relate to the action of the vocal folds while the latter reflect the geometry of the speaker's vocal tract. This set of features have been extracted from pause fillers, which are long enough for robust feature estimation while spontaneous enough to be extracted from voice samples in real forensic casework...
November 17, 2016: Forensic Science International
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