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https://www.readbyqxmd.com/read/28306621/prognostic-value-of-preoperative-18f-fdg-pet-ct-in-papillary-thyroid-cancer-patients-with-a-high-metastatic-lymph-node-ratio-a-multicenter-retrospective-cohort-study
#1
MULTICENTER STUDY
Seong Young Kwon, Eun Kyoung Choi, Eun Jung Kong, Ari Chong, Jung-Min Ha, Kyung Ah Chun, Ihn Ho Cho, Hee-Seung Bom, Jung-Joon Min, Jahae Kim, Ho-Chun Song, Joo Hyun O, Sung Hoon Kim
OBJECTIVE: Metastatic lymph node ratio (MLNR) is a known significant predictor of disease-free survival in differentiated thyroid cancer. The authors investigated the ability of preoperative fluorine-18 fluorodeoxyglucose (F-FDG) PET/CT to predict recurrence after surgery with radioactive iodine therapy considering MLNR. PATIENTS AND METHODS: A total of 274 patients who underwent preoperative PET/CT and surgery with radioactive iodine therapy were enrolled. The tumor-to-liver uptake ratio on PET/CT was calculated by dividing the maximum standardized uptake value of a primary lesion by the mean standardized uptake value of the normal liver...
May 2017: Nuclear Medicine Communications
https://www.readbyqxmd.com/read/28289595/case-report-of-a-novel-mutation-of-the-eya1-gene-in-a-patient-with-branchio-oto-renal-syndrome
#2
L Spahiu, B Merovci, V Ismaili Jaha, A Batalli Këpuska, H Jashari
Branchio-oto-renal (BOR) syndrome is an autosomal dominant disorder characterized by the coexistence of branchial cysts or fistulae, external ear malformation with pre-auricular pits or tags, hearing impairment and renal malformations. However, the presence of the main features varies in affected families. Here, we present a 16-year-old boy admitted to the Department of Nephrology at the Pediatric Clinic, University Clinical Center of Kosovo, Pristina, Republic of Kosovo because of severe renal insufficiency diagnosed 6 years ago, which progressed to end-stage renal failure...
December 1, 2016: Balkan Journal of Medical Genetics: BJMG
https://www.readbyqxmd.com/read/28250853/radiation-safety-in-nuclear-medicine-procedures
#3
REVIEW
Sang-Geon Cho, Jahae Kim, Ho-Chun Song
Since the nuclear disaster at the Fukushima Daiichi Nuclear Power Plant in 2011, radiation safety has become an important issue in nuclear medicine. Many structured guidelines or recommendations of various academic societies or international campaigns demonstrate important issues of radiation safety in nuclear medicine procedures. There are ongoing efforts to fulfill the basic principles of radiation protection in daily nuclear medicine practice. This article reviews important principles of radiation protection in nuclear medicine procedures...
March 2017: Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/28151897/preparation-for-radioactive-iodine-therapy-is-not-a-risk-factor-for-the-development-of-hyponatremia-in-thyroid-cancer-patients
#4
Jahae Kim, Sang-Geon Cho, Sae-Ryung Kang, Seong Young Kwon, Dong-Hyeok Cho, Jin-Seong Cho, Ho-Chun Song
The aim of this study was to evaluate whether the preparation for radioactive iodine (RAI) therapy by thyroid hormone withdrawal (THW) or a low-iodine diet (LID) can be risk factors for the development of hyponatremia in patients with differentiated thyroid cancer after thyroidectomy.We retrospectively reviewed the medical records and laboratory findings of 326 patients who underwent preparation for RAI therapy after thyroidectomy from 2012 to 2014. Demographic and clinical variables including the method of thyrotropin stimulation and duration of LID were assessed...
February 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27994691/giant-cell-tumor-with-secondary-aneurysmal-bone-cyst-shows-heterogeneous-metabolic-pattern-on-18-f-fdg-pet-ct-a-case-report
#5
Hee Jeong Park, Seong Young Kwon, Sang-Geon Cho, Jahae Kim, Ho-Chun Song, Sung Sun Kim, Yeon Hong Yoon, Jin Gyoon Park
Giant cell tumor (GCT) is a generally benign bone tumor accounting for approximately 5 % of all primary bone neoplasms. Cystic components in GCTs that indicate secondary aneurysmal bone cysts (ABCs) are reported in 14 % of GCTs. Although both of them have been described separately in previous reports that may show considerable fluorodeoxyglucose (FDG) uptake despite their benign nature, the findings of GCT with secondary ABC on (18)F-FDG positron emission tomography/computed tomography (PET/CT) have not been well-known...
December 2016: Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/27994688/iodine-uptake-patterns-on-post-ablation-whole-body-scans-are-related-to-elevated-serum-thyroglobulin-levels-after-radioactive-iodine-therapy-in-patients-with-papillary-thyroid-carcinoma
#6
Geum-Cheol Jeong, Minchul Song, Hee Jeong Park, Jung-Joon Min, Hee-Seung Bom, Sang-Geon Cho, Ki Seong Park, Sae-Ryung Kang, Jahae Kim, Ho-Chun Song, Seong Young Kwon
PURPOSE: Serum thyroglobulin (Tg) level is frequently elevated shortly after radioactive iodine (RAI) ablation therapy. The authors studied the relationship between the elevation of serum Tg after RAI therapy and iodine uptake pattern on post-ablation whole body scans (RxWBSs) in patients with papillary thyroid carcinoma (PTC). MATERIALS AND METHODS: The study subjects were patients with PTC that had undergone first RAI therapy with thyroid hormone withdrawal after total thyroidectomy...
December 2016: Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/27930593/usefulness-of-3-dimensional-stereotactic-surface-projection-fdg-pet-images-for-the-diagnosis-of-dementia
#7
COMPARATIVE STUDY
Jahae Kim, Sang-Geon Cho, Minchul Song, Sae-Ryung Kang, Seong Young Kwon, Kang-Ho Choi, Seong-Min Choi, Byeong-Chae Kim, Ho-Chun Song
To compare diagnostic performance and confidence of a standard visual reading and combined 3-dimensional stereotactic surface projection (3D-SSP) results to discriminate between Alzheimer disease (AD)/mild cognitive impairment (MCI), dementia with Lewy bodies (DLB), and frontotemporal dementia (FTD).[F]fluorodeoxyglucose (FDG) PET brain images were obtained from 120 patients (64 AD/MCI, 38 DLB, and 18 FTD) who were clinically confirmed over 2 years follow-up. Three nuclear medicine physicians performed the diagnosis and rated diagnostic confidence twice; once by standard visual methods, and once by adding of 3D-SSP...
December 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27848160/coronary-flow-reserve-and-relative-flow-reserve-measured-by-n-13-ammonia-pet-for-characterization-of-coronary-artery-disease
#8
Sang-Geon Cho, Ki Seong Park, Jahae Kim, Sae-Ryung Kang, Ho-Chun Song, Ju Han Kim, Jae Yeong Cho, Young Joon Hong, Zeenat Jabin, Hee Jeong Park, Geum-Cheol Jeong, Seong Young Kwon, Jin Chul Paeng, Hyeon Sik Kim, Jung-Joon Min, Ernest V Garcia, Henry Hee-Seung Bom
OBJECTIVE: We evaluated the relationships between coronary flow reserve (CFR) and relative flow reserve (RFR) measured by N-13 ammonia positron emission tomography (PET) for characterization of epicardial coronary artery disease (CAD). METHODS: Sixty-nine consecutive stable angina patients underwent N-13 ammonia PET, coronary computed tomography angiography (CCTA), and if necessary, invasive coronary angiography (CAG) within 2 weeks. Myocardial blood flow (MBF), CFR, RFR, and coronary vascular resistance of the reference arterial territory (CVRref) were measured by N-13 ammonia PET...
February 2017: Annals of Nuclear Medicine
https://www.readbyqxmd.com/read/27752746/clinical-values-of-left-ventricular-mechanical-dyssynchrony-assessment-by-gated-myocardial-perfusion-spect-in-patients-with-acute-myocardial-infarction-and-multivessel-disease
#9
Sang-Geon Cho, Zeenat Jabin, Ki Seong Park, Jahae Kim, Sae-Ryung Kang, Seong Young Kwon, Geum-Cheol Jeong, Minchul Song, Jong Sang Kim, Jae Yeong Cho, Hyun Kuk Kim, Ho-Chun Song, Jung-Joon Min, Hee-Seung Bom
PURPOSE: The aim of this study was to evaluate the prognostic value of additional evaluation of left ventricular mechanical dyssynchrony (LVMD) by gated myocardial perfusion single-photon emission computed tomography (GMPS) in patients with acute myocardial infarction (MI) and multivessel disease. METHODS: One hundred and nine acute MI patients with >50 % stenosis in at least one non-culprit artery who underwent GMPS within 2 weeks were enrolled. All patients underwent successful revascularization of the culprit arteries...
February 2017: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/27683281/prediction-of-coronary-artery-calcium-progression-by-fdg-uptake-of-large-arteries-in-asymptomatic-individuals
#10
Sang-Geon Cho, Ki Seong Park, Jahae Kim, Sae-Ryung Kang, Seong Young Kwon, Hyun Ju Seon, Zeenat Jabin, Young Jae Kim, Geum-Cheol Jeong, Minchul Song, Ho-Chun Song, Jung-Joon Min, Hee-Seung Bom
PURPOSE: The purpose of this study is to evaluate whether fluorodeoxyglucose (FDG) uptake of the large arteries can predict coronary artery calcium (CAC) progression in asymptomatic individuals. METHODS: Ninety-six asymptomatic individuals who underwent FDG positron emission tomography (PET) and CAC scoring on the same day for health screening and follow-up CAC scoring ≥1 year after baseline studies (mean 4.3 years) were included. Vascular FDG uptake was measured and corrected for blood pool activity to obtain peak and average target-to-blood pool ratios (TBRpeak and TBRavg, respectively) for the carotid arteries, and ascending and abdominal aorta...
January 2017: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/27556792/brain-metastases-mimicking-hyperostosis-frontalis-interna-on-99mtc-hdp-bone-scintigraphy
#11
Sae-Ryung Kang, Jahae Kim, Seong Young Kwon, Jung-Joon Min, Hee-Seung Bom, Myung-Hee Sohn, Ho-Chun Song
Symmetric bifrontal uptake of bone-seeking agents is usually considered as the main feature of hyperostosis frontalis interna in postmenopausal elderly women. This finding is not uncommon in elderly women because of the change in their hormonal level. However, in the present case, a 66-year-old woman with intra-axial brain metastases of breast cancer showed symmetric bifrontal uptake on bone scintigraphy. Therefore, symmetric bifrontal uptake should not always be considered as a definite indicator of hyperostosis frontalis interna...
October 2016: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/27540425/open-mouth-bone-scintigraphy-is-better-than-closed-mouth-bone-scintigraphy-in-the-diagnosis-of-temporomandibular-osteoarthritis
#12
Ki Seong Park, Ho-Chun Song, Sang-Geon Cho, Sae-Ryung Kang, Jahae Kim, Haeng Man Jun, Minchul Song, Geum-Cheol Jeong, Hee Jeong Park, Seong Young Kwon, Jung-Joon Min, Henry Hee-Seung Bom
PURPOSE: Closed-mouth bone scintigraphy (CM scan) and closed-mouth single-photon emission computed tomography (CM SPECT) are used for conventional evaluation of osteoarthritis of the temporomandibular joint (TMJ). However, the adequacy of open-mouth bone scintigraphy (OM scan) has not yet been evaluated. Therefore, the purpose of this study was to compare the diagnostic performance of CM scan, CM SPECT, and OM scan. METHODS: Thirty-six patients with suspicion of an abnormality of the TMJ and who underwent a (99m)Tc-HDP CM scan, CM SPECT, and an OM scan were enrolled...
September 2016: Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/27470328/-18-f-fdg-pet-ct-imaging-factors-that-predict-ischaemic-stroke-in-cancer-patients
#13
Jahae Kim, Kang-Ho Choi, Ho-Chun Song, Joon-Tae Kim, Man-Seok Park, Ki-Hyun Cho
PURPOSE: (18)F-FDG PET/CT can acquire both anatomical and functional images in a single session. We investigated which factors of (18)F-FDG PET/CT imaging have potential as biomarkers for an increased risk of ischaemic stroke in cancer patients. METHODS: From among cancer patients presenting with various neurological symptoms and hemiparesis, 134 were selected as eligible for this retrospective analysis. A new infarct lesion on brain MRI within 1 year of FDG PET/CT defined future ischaemic stroke...
November 2016: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/27158678/n-terminal-dentin-sialoprotein-fragment-induces-type-i-collagen-production-and-upregulates-dentinogenesis-marker-expression-in-osteoblasts
#14
Haytham Jaha, Dina Husein, Yoshio Ohyama, Dongliang Xu, Shigeki Suzuki, George T-J Huang, Yoshiyuki Mochida
Bone and dentin are mineralized extracellular matrices produced by osteoblasts and odontoblasts, respectively, and their major organic portion is type I collagen. Dentinogenesis Imperfecta (DGI) is one of the most common clinically- and genetically-based disturbances of dentin formation, causing irreversible dentin defects. Among several types of DGI, patients with DGI type II exhibit opalescent dentin with partial or complete pulp obliteration. It has been previously reported that the non-sense mutation (c...
June 2016: Biochemistry and Biophysics Reports
https://www.readbyqxmd.com/read/26954372/tenofovir-alafenamide-as-part-of-a-salvage-regimen-in-a-patient-with-multi-drug-resistant-hiv-and-tenofovir-df-associated-renal-tubulopathy
#15
James M Mikula, Maura M Manion, Frank Maldarelli, Lucila M Suarez, Jaha F Norman-Wheeler, Alex G Ober, Robin L Dewar, Jeffrey B Kopp, H Clifford Lane, Alice K Pau
We describe a patient with two recent episodes of tenofovir disoproxil fumarate (TDF)-associated acute kidney injury and six-class drug-resistant HIV infection who achieved and maintained viral suppression without worsening kidney function on a regimen including tenofovir alafenamide (TAF) through 48 weeks of therapy. The safety and efficacy of TAF in patients with TDF-associated renal tubulopathy and multiple drug resistant HIV has not yet been described. TAF may represent a useful option to maximally suppress HIV in patients with these complications...
2016: Antiviral Therapy
https://www.readbyqxmd.com/read/26941860/correlation-of-angina-pectoris-and-perfusion-decrease-by-collateral-circulation-in-single-vessel-coronary-chronic-total-occlusion-using-myocardial-perfusion-single-photon-emission-computed-tomography
#16
Sang-Geon Cho, Ki Seong Park, Sae-Ryung Kang, Jahae Kim, Haeng Man Jun, Jae Yeong Cho, Hae Chang Jeong, Ju Han Kim, Geum-Cheol Jeong, Hee Jeong Park, Seong Young Kwon, Jung-Joon Min, Henry Hee-Seung Bom, Ho-Chun Song
PURPOSE: To evaluate the perfusion decrease in donor myocardium by collateral circulation and its correlation with angina pectoris in patients with chronic total occlusion (CTO) using myocardial perfusion single-photon emission computed tomography (MPS). MATERIALS AND METHODS: Thirty-six patients with single-vessel CTO without any other stenosis were included. All patients underwent MPS and coronary angiography (CAG) within 2 months. Total 72 donor arteries were evaluated for the grades of collaterals to the CTO artery using the Rentrop grading system on CAG...
March 2016: Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/26244042/comparing-the-accuracy-of-the-three-dehydration-scales-in-children-with-acute-diarrhea-in-a-developing-country-of-kosovo
#17
Teuta Hoxha, Luan Xhelili, Mehmedali Azemi, Muharrem Avdiu, Vlora Ismaili-Jaha, Urata Efendija-Beqa, Violeta Grajcevci-Uka
BACKGROUND: Although diarrhea is a preventable disease, it remains the second leading cause of death (after pneumonia) among children aged under five years worldwide. The World Health Organization (WHO) scale, the Gorelick scale, and the Clinical Dehydration Scale (CDS) were created to estimate dehydration status using clinical signs. The purpose of this study is to determine whether these clinical scales can accurately assess dehydration status of children in a developing country of Kosovo...
June 2015: Materia Socio-medica
https://www.readbyqxmd.com/read/26164179/preablative-stimulated-thyroglobulin-levels-can-predict-malignant-potential-and-therapeutic-responsiveness-of-subcentimeter-sized-18f-fluorodeoxyglucose-avid-cervical-lymph-nodes-in-patients-with-papillary-thyroid-cancer
#18
Seong Young Kwon, Jahae Kim, Se Hee Jung, Ari Chong, Ho-Chun Song, Hee-Seung Bom, Jung-Joon Min
PURPOSE: We investigated the potential value of TSH-stimulated serum thyroglobulin (sTg) to characterize subcentimeter-sized, F-FDG avid cervical lymph nodes (LNs) on 18PET/CT and their responsiveness to 131I ablation therapy (IAT) in patients with papillary thyroid cancer. MATERIALS AND METHODS: We enrolled 49 patients who were undergoing total thyroidectomy and had incidentally detected FDG-avid LNs on PET/CT before IAT. According to the follow-up results, FDG-avid LNs were classified into 2 groups: those with metastatic LNs (group A) and those with benign LNs (group B)...
January 2016: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/26098289/18f-fdg-pet-ct-findings-of-scrub-typhus
#19
Jahae Kim, Seong Young Kwon, Sae-Ryung Kang, Sang-Geon Cho, Ho-Chun Song
Scrub typhus is an acute infectious disease caused by Orienta tsutsugamushi, which is clinically manifested by fever, generalized lymphadenopathy, diffuse myalgia, headache, maculopapular rash, and eschars at the site of chigger feedings. Diagnosis of scrub typhus requires compatible clinical features, history of exposure, and result of selorogic testing. In recent years, F-FDG PET/CT is seen as having increasing potential for use in examination and management of patients with infectious or inflammatory disorders...
October 2015: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/25947574/pulmonary-tuberculosis-mimicking-pulmonary-metastases-on-%C3%A2-%C3%A2-%C3%A2-i-post-therapeutic-scan
#20
Jahae Kim, Seong Young Kwon, Jung-Joon Min, Hee-Seung Bom, Ho-Chun Song
No abstract text is available yet for this article.
August 2015: European Journal of Nuclear Medicine and Molecular Imaging
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