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https://www.readbyqxmd.com/read/28823133/genetic-association-of-swine-leukocyte-antigen-class-ii-haplotypes-and-body-weight-in-microminipigs
#1
Tatsuya Matsubara, Masaki Takasu, Noriaki Imaeda, Naohito Nishii, Satoshi Takashima, Takashi Nishimura, Toshiaki Nishimura, Takashi Shiina, Asako Ando, Hitoshi Kitagawa
Objective: Microminipigs are a novel animal model with extensive applications in laboratory studies owing, in part, to their extremely small body sizes. In this study, the relationship between swine leukocyte antigen (SLA) class II haplotype and body weight was evaluated in the Microminipig population. Methods: A total of 1,900 haplotypes, covering SLA class II haplotypes Lr-0.7, Lr-0.23, Lr-0.17, Lr-0.37, Lr-0.16, Lr-0.11, Lr-0.13, and Lr-0.18, were analyzed in 950 piglets...
August 16, 2017: Asian-Australasian Journal of Animal Sciences
https://www.readbyqxmd.com/read/28822656/phenylephrine-infusion-impact-on-surgical-site-infections-after-lower-extremity-bypass-surgery
#2
Craig Curry, Jens Eldrup-Jorgensen, Janelle Richard, Michele C Siciliano, Wendy Y Craig
OBJECTIVE: Lower extremity bypass (LEB) operations have high rates of surgical site infections (SSI). Phenylephrine is a commonly used vasoconstrictor which may reduce skin blood flow and increase the likelihood of SSI in these patients. We studied the potential effect of phenylephrine infusion during LEB surgery on SSI. METHODS: LEB cases and their demographic data were identified through the Vascular Quality Initiative registry. SSI in this population was identified using the hospital epidemiology surveillance database...
August 16, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28822329/changes-in-gluteal-muscle-forces-with-alteration-of-footstrike-pattern-during-running
#3
Charles Nathan Vannatta, Thomas W Kernozek, Naghmeh Gheidi
Gait retraining is a common form of treatment for running related injuries. Proximal factors at the hip have been postulated as having a role in the development of running related injuries. How altering footstrike affects hip muscles forces and kinematics has not been described. Thus, we aimed to quantify differences in hip muscle forces and hip kinematics that may occur when healthy runners are instructed to alter their foot strike pattern from their habitual rear-foot strike to a forefoot strike. This may gain insight on the potential etiology and treatment methods of running related lower extremity injury...
August 9, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28822311/lingular-segment-torsion-following-a-left-upper-division-segmentectomy
#4
Naohiro Taira, Hidenori Kawasaki, Sayako Takahara, Tomonori Furugen, Takaharu Ichi, Kazuaki Kushi, Tomofumi Yohena, Tsutomu Kawabata
INTRODUCTION: Numerous publications regarding lung torsion have reported lobar torsion after lobectomy. On the other hand, torsion of the remaining segment after segmentectomy is extremely rare. We herein report a rare case of lingular segment torsion following a left upper division segmentectomy. CASE: A 68-year old female underwent thoracoscopic segmentectomy of the left upper division. She underwent chest radiography immediately after the initial surgery, which revealed complete expansion on the operated side...
August 4, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28822177/-berberine-regulates-type-2-diabetes-mellitus-related-with-insulin-resistance
#5
REVIEW
Cheng Li, Jin-Zhi He, Xue-Dong Zhou, Xin Xu
Insulin resistance (IR) is defined as a series of clinical manifestations for diminished effectiveness of insulin in lowering blood sugar levels caused by decreased sensitivity to insulin of liver, muscle and adipose tissue. IR is the major contributor to the etiology and pathogenesis of type 2 diabetes mellitus (T2DM). Berberine, a traditional Chinese herb extract, has been shown to be safe and effective in lowering blood sugar, alleviating insulin resistance and moderating type 2 diabetes mellitus and its complications...
June 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/28821443/the-effect-of-pelvic-motion-on-spino-pelvic-parameters
#6
Andrew M Hayden, Ann M Hayes, Jennifer L Brechbuhler, Heidi Israel, Howard M Place
BACKGROUND CONTEXT: To date, many studies have examined how pelvic position affects the spinal curvature and spino-pelvic parameters. However, these studies focus on a static relationship, comparing pelvis and spine in a relaxed or baseline position only. Indeed, the spino-pelvic connection is dynamic, as a subject can easily be taught to rotate their pelvis anteriorly or posteriorly on the femoral head, all while maintaining an erect posture. Therefore, for a true understanding of pelvic influence on the spinal column, it is necessary to examine spino-pelvic parameters in multiple pelvic positions within the same subject...
August 15, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28821268/hypo-fractionated-sbrt-for-localized-prostate-cancer-a-german-bi-center-single-treatment-group-feasibility-trial
#7
Ping Jiang, Katja Krockenberger, Reinhard Vonthein, Jane Tereszczuk, Arne Schreiber, Sebastian Liebau, Stefan Huttenlocher, Detlef Imhoff, Panagiotis Balermpas, Christian Keller, Kathrin Dellas, Rene Baumann, Claus Rödel, Guido Hildebrandt, Klaus-Peter Jünemann, Alex S Merseburger, Alan Katz, Andreas Ziegler, Oliver Blanck, Jürgen Dunst
BACKGROUND: For prostate cancer treatment, treatment options with minimal side effects are desired. External beam radiation therapy (EBRT) is non-invasive, standard of care and delivered in either conventional fractionation over 8 weeks or with moderate hypo-fractionation over about 5 weeks. Recent advances in radiotherapy technology have made extreme hypo-fractionated stereotactic body radiation therapy (SBRT) of prostate cancer feasible, which has not yet been introduced as a standard treatment method in Germany...
August 18, 2017: Radiation Oncology
https://www.readbyqxmd.com/read/28821225/differences-in-survival-virulence-and-biofilm-formation-between-sialidase-deficient-and-w83-wild-type-porphyromonas-gingivalis-strains-under-stressful-environmental-conditions
#8
Xiaoyu Xu, Tong Tong, Xue Yang, Yaping Pan, Li Lin, Chen Li
BACKGROUND: Porphyromonas gingivalis is a major causative pathogen of chronic periodontitis. Within the inflammatory microenvironment, there exists extreme pH values, elevated temperatures and oxidative stress. Pathogens adapt to these stressful environmental conditions by regulating the transcription of virulence genes, modifying themselves with macromolecules and by aggregating and entering into a biofilm growth phase. Our previous study showed that the P. gingivalis sialidase can help cells obtain sialic acid from the environment, which is used to modify macromolecules on the surface of P...
August 18, 2017: BMC Microbiology
https://www.readbyqxmd.com/read/28821072/understanding-the-mechanisms-of-oxygen-diffusion-through-surface-functionalized-nanocellulose-films
#9
Maria Soledad Peresin, Kari Kammiovirta, Harri Heikkinen, Leena-Sisko Johansson, Jari Vartiainen, Harri Setälä, Monika Österberg, Tekla Tammelin
A concept for direct surface modification on self-standing films of cellulose nanofibrils (CNF) is demonstrated using an aminosilane group in cellulose compatible solvent (dimethyl acetamide, DMA). The chemically modified structure efficiently prevents the oxygen molecules from interacting with the nanocellulose film in the presence of water molecules. Oxygen permeability values lower than 1mLmmm(-2)day(-1)atm(-1) were achieved at extremely high levels of relative humidity (RH95%). The aminosilane reaction is compared to conventional hydrophobization reaction using hexamethyldisilazane...
October 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28820359/clinical-outcomes-of-direct-oral-anticoagulants-after-lower-extremity-arterial-procedures
#10
Afsha Aurshina, Pavel Kibrik, Justin Eisenberg, Ahmad Alsheekh, Anil Hingorani, Natalie Marks, Enrico Ascher
Objectives The use of postoperative anticoagulation is not uncommon for patients undergoing lower extremity arterial procedures as adjunctive therapy. Longer postoperative length of stay is necessary to achieve adequate therapeutic international normalized ratio with traditional protocols that call for the use of unfractionated heparin and warfarin therapy. We hypothesized the direct oral anticoagulants are an attractive alternative to provide adequate anticoagulation in patients who undergo lower extremity arterial procedures...
January 1, 2017: Vascular
https://www.readbyqxmd.com/read/28819879/lower-extremity-bypass-using-bovine-carotid-artery-graft-artegraft-an-analysis-of-124-cases-with-long-term-results
#11
Philip Lindsey, Angela Echeverria, Mathew Cheung, Elias Kfoury, Carlos F Bechara, Peter H Lin
INTRODUCTION: Although biological grafts have been utilized as a vascular conduit in leg bypass for many years, reports of a bovine carotid artery graft (BCAG) in lower extremity revascularization have been scarce. This study analyzed the outcome of lower leg bypass using BCAG. METHODS: A retrospective review of a prospectively collected database of all patients undergoing lower extremity bypass using BCAG from 2002 to 2017 was performed. Clinical outcomes including graft patency and limb salvage were evaluated...
August 17, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/28819829/surgical-treatment-for-symptomatic-non-ossifying-fibromas-of-the-lower-extremity-with-calcium-sulfate-grafts-in-skeletally-immature-patients
#12
Antonio Andreacchio, Flavia Alberghina, Gianluca Testa, Federico Canavese
BACKGROUND: Non-ossifying fibromas (NOFs) are common benign bone lesions found in children and adolescents. They usually involve metaphysis of long bones, tend to gradually disappear with age and usually do not require surgery, while they are not associated with pathological fractures. The aim of this study was to evaluate the outcome and efficacy of a single-stage procedure, comprising curettage of the lesion and calcium sulfate pellet (CaSP) grafting, in skeletally immature patients with large, symptomatic NOF of the lower extremity, and the possible limitations of the procedure...
August 17, 2017: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/28819743/halorubrum-salsamenti-sp-nov-a-novel-halophilic-archaeon-isolated-from-a-brine-of-salt-mine
#13
Shaoxing Chen, Jiao He, Jiao Zhang, Yao Xu, Jiao Huang, Li-Xia Ke
A non-motile, spherical or oval extremely halophilic archaeon, strain Y69(T), was isolated from a brine of the Yunnan salt mine, China. Colonies on JCM 168 agar plate were round (1-2 mm in diameter), moist, and orange-pigmented. Phylogenetic analysis of the almost-complete 16S rRNA gene sequence showed that the isolate belonged to the species of the genus Halorubrum, with a close relationship to Halorubrum aidingense 31-hong(T) (98.5%), Halorubrum lacusprofundi ATCC 49239(T) (98.2%), and Halorubrum kocurii BG-1(T) (98...
August 17, 2017: Current Microbiology
https://www.readbyqxmd.com/read/28819631/effect-of-tranexamic-acid-on-hematologic-values-and-blood-loss-in-reverse-total-shoulder-arthroplasty
#14
Sae Hoon Kim, Whan Ik Jung, Young Jun Kim, Do Hyeon Hwang, Young Eun Choi
PURPOSE: Use of tranexamic acid (TXA) in the setting of arthroplasty of the lower extremity has been previously described. The aim of this study was to evaluate the benefit of a single dose of TXA (500 mg vial) administered intravenously just prior to RTSA in an Asian population. METHODS: The records of 48 patients (no TXA, n = 24, versus TXA, n = 24) that underwent RTSA for cuff tear arthropathy were retrospectively reviewed. All patients had a Hemovac drain positioned for 2 days after surgery...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28818700/vascularized-jejunal-mesenteric-lymph-node-transfer-a-novel-surgical-treatment-for-extremity-lymphedema
#15
Michelle Coriddi, Corrine Wee, Joseph Meyerson, Daniel Eiferman, Roman Skoracki
BACKGROUND: Vascularized lymph node transfer (VLNT) is a surgical treatment for lymphedema. Multiple donor sites have been described and each has significant disadvantages. We propose the jejunal mesentery as a novel donor site for VLNT. METHODS: Cadaveric anatomic study analyzing jejunal lymph nodes (LNs) and description of outcomes from the first patients who received jejunal mesenteric VLNT for treatment of lymphedema. RESULTS: In 5 cadavers, the average number of total LNs and peripheral LNs were identified in the proximal, middle and distal segments of jejunum...
August 14, 2017: Journal of the American College of Surgeons
https://www.readbyqxmd.com/read/28818476/complex-anatomic-abnormalities-of-the-lower-leg-muscles-and-tendons-associated-with-phocomelia-a-case-report
#16
Thomas Hodo, Mark Hamrick, Yulia Melenevsky
Musculoskeletal anatomy is widely known to have components that stray from the norm in the form of variant muscle and tendon presence, absence, origin, insertion, and bifurcation. Although these variant muscles and tendons might be deemed incidental and insignificant findings by most, they can be important contributors to pathologic physiology or, more importantly, an option for effective treatment. In the present case report, we describe a patient with phocomelia and Müllerian abnormalities secondary to in utero thalidomide exposure...
August 14, 2017: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/28818338/spinal-anesthesia-for-pediatric-urological-surgery-reducing-the-theoretic-neurotoxic-effects-of-general-anesthesia
#17
Emmett E Whitaker, Brianne Z Wiemann, Daniel G DaJusta, Seth A Alpert, Christina B Ching, Daryl J McLeod, Joseph D Tobias, Venkata R Jayanthi
BACKGROUND: Spinal anesthesia (SA) is an effective technique that has been used in children for years. With growing concern with regard to the risks of general anesthesia (GA), we developed a SA program to provide an alternative option. We present our initial experience with this program. OBJECTIVE: To implement a SA program at a large tertiary care pediatric center and assess the safety and efficacy of the technique as an alternative to GA for urologic surgery...
July 14, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28818230/symptomatic-compression-of-right-iliac-vein-after-right-iliac-artery-stent-placement
#18
Lindsay Young, Jeontaik Kwon, Mariano Arosemena, Dawn Salvatore, Paul DiMuzio, Babak Abai
Right lower extremity edema can be a presenting symptom of iliocaval compression syndrome, even in the absence of deep vein thrombosis. It has been reported in idiopathic and rarely, iatrogenic, cases secondary to variant anatomy, arterial stents, and bony hardware. Classically seen in the more confined left common iliac vein as May-Thurner syndrome, it is rare on the right side. We report an unusual case of acute right common iliac vein compression after right iliac stent placement leading to symptomatic right leg edema...
September 2017: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/28818213/the-natural-history-and-outcomes-of-line-associated-upper-extremity-deep-venous-thromboses-in-critically-ill-patients
#19
Joshua Underhill, Matthew A Sherman, Ryan Howard, Anthony Hage, Andrea Obi, Lena Napolitano, Dawn M Coleman
OBJECTIVE: Anticoagulation remains the standard of care for line-associated upper extremity deep venous thrombosis (UEDVT). This treatment carries the risk of hemorrhagic complications, possibly more so in surgical patients. Considering the low-risk profile of UEDVT-which is associated with fewer, less severe pulmonary emboli than lower extremity deep venous thrombosis-current UEDVT treatment guidelines may be overly aggressive. The goal of this study was to review outcomes of line-associated UEDVT in critically ill patients and to define the efficacy of current treatment protocols in pulmonary embolism (PE) prevention while avoiding hemorrhagic complications...
September 2017: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/28818211/evaluation-of-thrombolysis-using-tissue-plasminogen-activator-in-lower-extremity-deep-venous-thrombosis-with%C3%A2-concomitant-femoral-popliteal-venous-segment%C3%A2-involvement
#20
Mayin Lin, John C F Hsieh, Mian Hanif, Alan McDaniel, David K Chew
OBJECTIVE: Current guidelines recommend thrombolytic therapy for iliofemoral deep venous thrombosis (DVT). Anticoagulation is the standard treatment for femoral-popliteal and tibial-level DVT. The objective of this study was to evaluate the efficacy of catheter-directed thrombolysis (CDT) using tissue plasminogen activator vs standard anticoagulation alone in patients with lower extremity DVT involving the femoral-popliteal segment. METHODS: A retrospective review was performed of patients referred to the vascular surgery service with lower extremity DVT from 2006 to 2015...
September 2017: Journal of Vascular Surgery. Venous and Lymphatic Disorders
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