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https://www.readbyqxmd.com/read/28723844/associations-of-physical-activity-intensities-with-markers-of-insulin-sensitivity
#1
Charlotte Jelleyman, Charlotte L Edwardson, Joseph Henson, Laura J Gray, Alex V Rowlands, Kamlesh Khunti, Melanie J Davies, Thomas Yates
BACKGROUND: Objectively measured physical activity (PA) intensity has traditionally been categorised as light, moderate and vigorous using laboratory calibrated cut-points. The relative contribution of time spent across a spectrum of accelerometer-determined intensities on health outcomes is less clear. PURPOSE: To assess the relationship between objectively measured PA intensity on a continuous scale and markers of insulin sensitivity. METHODS: Participants at high risk of type 2 diabetes were recruited from primary care (Leicestershire, UK)...
July 19, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28722815/influence-of-morphine-and-naloxone-on-pain-modulation-in-rheumatoid-arthritis-chronic-fatigue-syndrome-fibromyalgia-and-controls-a-double-blind-randomized-placebo-controlled-cross-over-study
#2
Linda Hermans, Jo Nijs, Patrick Calders, Luc De Clerck, Greta Moorkens, Guy Hans, Sofie Grosemans, Tine Roman De Mettelinge, Joanna Tuynman, Mira Meeus
BACKGROUND: Impaired pain inhibitory and enhanced pain facilitatory mechanisms are repeatedly reported in patients with central sensitization pain. However, the exact effects of frequently prescribed opioids on central pain modulation are still unknown. METHODS: A randomized, double-blind, placebo-controlled cross-over trial was carried out. Ten CFS/FM patients, 11 RA patients and 20 controls were randomly allocated to the experimental (10 mg morphine or 0.2 mg/ml Naloxone) and placebo (2 ml Aqua) group...
July 19, 2017: Pain Practice: the Official Journal of World Institute of Pain
https://www.readbyqxmd.com/read/28721082/effectiveness-evaluation-of-two-volumizing-hyaluronic-acid-dermal-fillers-in-a-controlled-randomized-double-blind-split-face-clinical-study
#3
Martina Kerscher, Karla Agsten, Maria Kravtsov, Welf Prager
BACKGROUND: Enhancement of the midface can be achieved with volumizing hyaluronic acid (HA) fillers. OBJECTIVE: The objective of this study was to compare the safety and effectiveness of Cohesive Polydensified Matrix(®) 26 mg/mL HA gel (CPM-26) and Vycross(®) 20 mg/ml HA gel (VYC-20) in a controlled, randomized, evaluator-blind, split-face clinical study. PATIENTS AND METHODS: Subjects with moderate-to-severe malar volume loss on the Merz Aesthetics Scale (MAS) received CPM-26 on one side and VYC-20 on the contralateral side of the face...
2017: Clinical, Cosmetic and Investigational Dermatology
https://www.readbyqxmd.com/read/28711188/plan-delivery-quality-assurance-for-cyberknife-statistical-process-control-analysis-of-350-film-based-patient-specific-qas
#4
J Bellec, N Delaby, F Jouyaux, M Perdrieux, J Bouvier, S Sorel, O Henry, C Lafond
PURPOSE: Robotic radiosurgery requires plan delivery quality assurance (DQA) but there has never been a published comprehensive analysis of a patient-specific DQA process in a clinic. We proposed to evaluate 350 consecutive film-based patient-specific DQAs using statistical process control. We evaluated the performance of the process to propose achievable tolerance criteria for DQA validation and we sought to identify suboptimal DQA using control charts. METHODS AND MATERIAL: DQAs were performed on a CyberKnife-M6 using Gafchromic-EBT3 films...
July 2017: Physica Medica: PM
https://www.readbyqxmd.com/read/28709954/modulation-of-itch-by-conditioning-itch-and-pain-stimulation-in-healthy-humans
#5
H H Andersen, A I M van Laarhoven, J Elberling, L Arendt-Nielsen
Little is known about endogenous descending control of itch. In chronic pain, descending pain inhibition is reduced as signified by lowered conditioned pain modulation (CPM). There are indications that patients with chronic itch may also exhibit reduced endogenous descending inhibition of itch and pain. This study aimed to investigate whether and the extent to which itch can be modulated by conditioning itch and pain stimuli. Twenty-six healthy volunteers participated. The study consisted of 5 conditions designed to systematically assess endogenous modulation of itch or pain: 1) itch-induced modulation of contralateral itch, 2) pain-induced modulation of contralateral itch, 3) pain-induced modulation of ipsilateral itch, 4) pain-induced modulation of contralateral pain, and 5) itch-induced modulation of contralateral pain...
July 11, 2017: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/28699193/outcomes-of-laryngohyoid-suspension-techniques-in-an-ovine-model-of-profound-oropharyngeal-dysphagia
#6
Christopher M Johnson, Naren N Venkatesan, M Tausif Siddiqui, Daniel J Cates, Maggie A Kuhn, Gregory M Postma, Peter C Belafsky
OBJECTIVES/HYPOTHESIS: To evaluate the efficacy of various techniques of laryngohyoid suspension in the elimination of aspiration utilizing a cadaveric ovine model of profound oropharyngeal dysphagia. STUDY DESIGN: Animal study. METHODS: The head and neck of a Dorper cross ewe was placed in the lateral fluoroscopic view. Five conditions were tested: baseline, thyroid cartilage to hyoid approximation (THA), thyroid cartilage to hyoid to mandible (laryngohyoid) suspension (LHS), LHS with cricopharyngeus muscle myotomy (LHS-CPM), and cricopharyngeus muscle myotomy (CPM) alone...
July 12, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28697210/reproducibility-of-a-new-computerized-planimetric-method-for-the-measurement-and-assessment-of-removable-dental-prostheses-plaque
#7
Ahmad Al Jaghsi, Torsten Mundt, Reiner Biffar
PURPOSE: The aim of this study was to evaluate the reliability and agreement of a new computerized planimetric method (CPM) for the measurement and assessment of plaque on all types of removable dental prostheses (RDPs). MATERIALS AND METHODS: From a database containing 780 images taken following a standardized method for 65 RDPs, 55 images were randomly selected for image analysis. Adobe Photoshop software was used according to standard operating procedure (SOP) by one main examiner two times in different sessions, and one time by three additional examiners...
July 2017: International Journal of Prosthodontics
https://www.readbyqxmd.com/read/28678697/in-ear-audio-wearable-measurement-of-heart-and-breathing-rates-for-health-and-safety-monitoring
#8
Alexis Martin, Jeremie Voix
OBJECTIVE: This paper examines the integration of a non-invasive vital sign monitoring feature into the workers' hearing protection devices (HPDs) by using a microphone positioned within the earcanal under the HPD. METHODS: 25 test-subjects were asked to breathe at various rhythms and intensities and these realistic sound events were recorded in the earcanal. Digital signal processing algorithms were then developed to assess heart and breathing rates. Finally, to test the robustness of theses algorithms in noisy work environments, industrial noise was added to the in-ear recorded signals and an adaptive denoising filter was used...
June 27, 2017: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/28672044/life-cycle-energy-efficiency-and-environmental-impact-assessment-of-bioethanol-production-from-sweet-potato-based-on-different-production-modes
#9
Jun Zhang, Chunrong Jia, Yi Wu, Xunfeng Xia, Beidou Xi, Lijun Wang, Youlong Zhai
The bioethanol is playing an increasingly important role in renewable energy in China. Based on the theory of circular economy, integration of different resources by polygeneration is one of the solutions to improve energy efficiency and to reduce environmental impact. In this study, three modes of bioethanol production were selected to evaluate the life cycle energy efficiency and environmental impact of sweet potato-based bioethanol. The results showed that, the net energy ratio was greater than 1 and the value of net energy gain was positive in the three production modes, in which the maximum value appeared in the circular economy mode (CEM)...
2017: PloS One
https://www.readbyqxmd.com/read/28670654/comparative-study-of-27-gauge-and-25-gauge-vitrectomy-performed-as-day-surgery
#10
Ryusaburo Mori, Saigen Naruse, Hiroyuki Shimada
PURPOSE: To compare postoperative outcomes of 27-gauge (G) and 25-G vitrectomy conducted as day surgery. METHODS: In total, 200 consecutive eyes that underwent primary vitrectomy (27-G in 100 eyes, 25-G in 100 eyes) were analyzed. 27-G vitrectomy was performed using a cut rate of 7500 cpm and 25-G vitrectomy using a cut rate of 5000 cpm. RESULTS: The 27-G and 25-G groups did not differ significantly in underlying diseases and preoperative Early Treatment Diabetic Retinopathy Study (ETDRS) score...
July 3, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28666919/age-molecular-subtypes-and-local-therapy-decision-making
#11
Anne Kuijer, Tari A King
The relationship between age and breast cancer subtype is complex: both impact risk of locoregional recurrence (LRR) and survival. Young patients frequently present with aggressive tumors but the increased risk imparted by young age appears to differ among breast cancer subtypes. Dramatic improvements in local control among young women with breast cancer of all tumor subtypes have been observed, likely attributable to improved local therapy strategies, improvements in adjuvant therapies and implementation of subtype-specific targeted therapies...
June 27, 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28666428/descriptive-analysis-of-preschool-physical-activity-and-sedentary-behaviors-a-cross-sectional-study-of-3-year-olds-nested-in-the-skot-cohort
#12
Niels Christian Møller, Line B Christensen, Christian Mølgaard, Katrine T Ejlerskov, Karin A Pfeiffer, Kim F Michaelsen
BACKGROUND: Further collection of surveillance data is warranted, particularly in preschool populations, for optimizing future public health promotion strategies. This study aims to describe physical activity (PA) and sedentary behavior (SB) across different settings, including time in and out of daycare, and to determine the proportion of children complying with suggested PA recommendations in a high income country. METHODS: Valid PA was assessed in 231 children (36...
June 30, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28665989/addition-of-transcranial-direct-current-stimulation-to-quadriceps-strengthening-exercise-in-knee-osteoarthritis-a-pilot-randomised-controlled-trial
#13
Wei-Ju Chang, Kim L Bennell, Paul W Hodges, Rana S Hinman, Carolyn L Young, Valentina Buscemi, Matthew B Liston, Siobhan M Schabrun
A randomised, assessor- and participant-blind, sham-controlled trial was conducted to assess the safety and feasibility of adding transcranial direct current stimulation (tDCS) to quadriceps strengthening exercise in knee osteoarthritis (OA), and provide data to inform a fully powered trial. Participants were randomised to receive active tDCS+exercise (AT+EX) or sham tDCS+exercise (ST+EX) twice weekly for 8 weeks whilst completing home exercises twice per week. Feasibility, safety, patient-perceived response, pain, function, pressure pain thresholds (PPTs) and conditioned pain modulation (CPM) were assessed before and after treatment...
2017: PloS One
https://www.readbyqxmd.com/read/28649032/a-standard-mastectomy-should-not-be-the-only-recommended-breast-surgical-treatment-for-non-metastatic-inflammatory-breast-cancer-a-large-population-based-study-in-the-surveillance-epidemiology-and-end-results-database-18
#14
Hongliang Chen, Kejin Wu, Maoli Wang, Fuwen Wang, Mingdi Zhang, Peng Zhang
BACKGROUND: Standard mastectomy has long been the recommended breast surgical treatment for non-metastatic inflammatory breast cancer (IBC). The objective of this population-based study was to evaluate the significance of various breast surgical treatments for this highly aggressive subtype. METHODS: The Surveillance, Epidemiology, and End Results program registry was searched to identify women with non-metastatic IBC receiving standard treatment including breast surgery, radiation therapy and chemotherapy diagnosed between 1998 and 2013...
June 22, 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28647922/comparison-of-quality-of-chest-compressions-during-training-of-laypersons-using-push-heart-and-little-anne-manikins-using-blinded-cprcards
#15
Shota Tanaka, Alexander E White, Ryo Sagisaka, Guanseng Chong, Eileen Ng, Jinny Seow, Nurul Asyikin Mj, Hideharu Tanaka, Marcus Eng Hock Ong
BACKGROUND: Mass Cardio-Pulmonary Resuscitation (CPR) training using less expensive and easily portable manikins is one way to increase the number of trained laypeople in a short time. The easy-to-carry, low-cost CPR training model called Push Heart (PH) is widely used in Japan. The aim of this study was to examine if PH can achieve chest compression quality that is similar to that using more conventional Little Anne (LA) manikins for training laypersons. METHODS: This prospective randomized crossover study was done during routine community CPR training of laypersons in Singapore...
December 2017: International Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28645867/psychophysical-and-electrophysiological-evidence-for-enhanced-pain-facilitation-and-unaltered-pain-inhibition-in-acute-low-back-pain-patients
#16
Pascal Henri Vuilleumier, Federico Gabriel Arguissain, José Alberto Biurrun Manresa, Alban Ymer Neziri, Arto Christian Nirkko, Ole Kæseler Andersen, Lars Arendt-Nielsen, Michele Curatolo
The aim of this case-control study was to examine differences in neural correlates of pain facilitatory and inhibitory mechanisms between acute low back pain patients and healthy individuals. Pressure pain tolerance (PPT), electrical pain detection thresholds (EDT), pain ratings to repetitive suprathreshold electrical stimulation (SES) and conditioned pain modulation (CPM) were assessed in 18 patients with acute low back pain (LBP) and 18 healthy controls (CTRL). Furthermore, event-related potentials (ERPs) in response to repetitive SES were obtained from high-density electroencephalography...
June 20, 2017: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/28640060/individualized-estimation-of-physical-activity-in-older-adults-with-type-2-diabetes
#17
Whitney A Welch, Neil Alexander, Ann M Swartz, Nora E Miller, Erica Twardzik, Scott J Strath
PURPOSE: Compare physical activity intensity in older adults with T2DM using individualized, relative cutpoints with standard, absolute cutpoints. METHODS: One hundred older adults with T2DM (68.9±5.1y, 65% male, 32.7±6.3 kgm, 7.2±1.1% HbA1c) completed a two-speed walking protocol (varying, walking between 1-2.5 mph), followed by a modified Bruce peak exercise test. Participants wore an accelerometer-based physical activity monitor at their waist and oxygen consumption was measured...
June 21, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28639039/a-novel-endoscopic-surgery-for-dysphagia-after-stroke
#18
Jian Wang, Wuyi Li, Yongjin Li, Xiaofeng Jin, Yanyan Niu, Xu Tian, Hong Huo
BACKGROUND: Dysphagia is a common complication in stroke patients, which severely affects quality of life. This study aimed to evaluate the effectiveness and safety of temperature-controlled plasma radiofrequency (coblation)-assisted endoscopic cricopharyngeal myotomy (CAECPM) for the treatment sustained (>6 months) dysphagia in stroke patients. METHODS: This retrospective case-control study included a total of 24 stroke patients with sustained dysphagia, who were either treated with transcervical cricopharyngeal myotomy (CPM) (n = 16) or CAECPM (n = 12)...
June 21, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28634720/the-financial-impact-and-drivers-of-hospital-charges-in-contralateral-prophylactic-mastectomy-and-reconstruction-a-nationwide-inpatient-sample-hospital-analysis
#19
Alexandra Bucknor, Anmol Chattha, Klaas Ultee, Winona Wu, Parisa Kamali, Patrick Bletsis, Austin Chen, Bernard T Lee, Claire Cronin, Samuel J Lin
PURPOSE: Rates of contralateral prophylactic mastectomy (CPM) have increased over the last decade; it is important for surgeons and hospital systems to understand the economic drivers of increased costs in these patients. This study aims to identify factors affecting charges in those undergoing CPM and reconstruction. METHODS: Analysis of the Healthcare Cost and Utilization Project National Inpatient Sample was undertaken (2009-2012), identifying women aged ≥18 with unilateral breast cancer undergoing unilateral mastectomy with CPM and immediate breast reconstruction (IBR) (CPM group), in addition to unilateral mastectomy and IBR alone (UM group)...
June 20, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28627793/increased-sympathetic-outflow-induces-adaptation-to-acute-experimental-pain
#20
Lior Dayan, Uri Hochberg, Hadas Nahman-Averbuch, Silviu Brill, Jacob N Ablin, Giris Jacob
BACKGROUND: There are interrelationships between the autonomic nervous system and pain. This study aims to explore the effect of different autonomic manipulations on pain perception and modulation. METHODS: Twenty healthy subjects (10 men and 10 women, mean age 25±3) participate in this single-blinded, semi-randomized, controlled study, which included 2 study visits. Warm and heat pain thresholds, conditioned pain modulation and pain adaptation were tested before and after administration of phenylephrine, clonidine, yohimbine and saline...
June 19, 2017: Pain Practice: the Official Journal of World Institute of Pain
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