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https://www.readbyqxmd.com/read/27919164/differences-in-allergic-inflammatory-responses-in-murine-lungs-comparison-of-pm2-5-and-coarse-pm-collected-during-the-hazy-events-in-a-chinese-city
#1
Miao He, Takamichi Ichinose, Seiichi Yoshida, Fumiko Shiba, Keiichi Arashidani, Hirohisa Takano, Guifan Sun, Takayuki Shibamoto
Urban particulate matter (PM) is associated with an increase in asthma. PM2.5 (<PM2.5 μm) and coarse PM (CPM: PM2.5-PM10 μm) were collected from the air in a Chinese city during haze events. The amounts of polycyclic aromatic hydrocarbons (PAHs) were higher in PM2.5 than in CPM. Conversely, microbial elements LPS and β-glucan were much higher in CPM than in PM2.5. Concentrations of Si, Al, Fe, and Ti in CPM were greater than in PM2.5, while Pb, Cu and As concentrations were lower than in PM2.5. When RAW264...
December 5, 2016: Inhalation Toxicology
https://www.readbyqxmd.com/read/27902566/conditioned-pain-modulation-in-non-specific-chronic-back-pain-patients-with-chronic-local-pain-chronic-widespread-pain-and-fibromyalgia
#2
Andreas Gerhardt, Wolfgang Eich, Rolf-Detlef Treede, Jonas Tesarz
Findings considering conditioned pain modulation (CPM) in chronic back pain (CBP) are contradictory. This might be because many CBP patients report pain in further areas of the body and altered CPM might influence spatial extent of pain rather than CBP per se. Therefore, we compared CPM in CBP patients with different pain extent. Fibromyalgia syndrome (FMS) patients, for whom CPM-impairment is reported most consistently, were measured for comparison.Based on clinical evaluation and pain-drawings patients were categorized into chronic local back pain (CLP; n=53), chronic widespread back pain (CWP; n=32), and FMS (n=92)...
November 28, 2016: Pain
https://www.readbyqxmd.com/read/27893785/are-older-adults-physically-active-enough-a-matter-of-assessment-method-the-generation-100-study
#3
Nils Petter Aspvik, Hallgeir Viken, Nina Zisko, Jan Erik Ingebrigtsen, Ulrik Wisløff, Dorthe Stensvold
INTRODUCTION: Physical activity (PA) is beneficial for general health. As a result, adults around the world are recommended to undertake regular PA of either absolute or relative intensity. Traditionally, adherence to PA recommendation is assessed by accelerometers that record absolute intensity thresholds. Since ageing often results in a decrease in cardiorespiratory fitness (CRF), older adults (aged > 65 years) might be more susceptible to not meeting the PA recommendation when measured in absolute terms...
2016: PloS One
https://www.readbyqxmd.com/read/27893249/sleep-spindles-and-intelligence-in-early-childhood-developmental-and-trait-dependent-aspects
#4
Péter P Ujma, Piroska Sándor, Sára Szakadát, Ferenc Gombos, Róbert Bódizs
Sleep spindles act as a powerful marker of individual differences in cognitive ability. Sleep spindle parameters correlate with both age-related changes in cognitive abilities and with the age-independent concept of IQ. While some studies have specifically demonstrated the relationship between sleep spindles and intelligence in young children, our previous work in older subjects revealed sex differences in the sleep spindle correlates of IQ, which was never investigated in small children before. We investigated the relationship between age, Raven Colored Progressive Matrices (CPM) scores and sleep spindles in 28 young children (age 4-8 years, 15 girls)...
December 2016: Developmental Psychology
https://www.readbyqxmd.com/read/27892835/effect-of-adhesive-restoration-and-bleaching-technique-on-the-concentration-of-hydrogen-peroxide-in-the-pulp-chamber
#5
V Cavalli, B G Silva, S B Berger, G Abuna, F C Marson, Cpm Tabchoury, M Giannini
This study aimed to quantify the concentration of hydrogen peroxide into the pulp chamber in the presence or absence of adhesive enamel restorations and to analyze the resin-dentin interface of bleached groups. Bovine incisors (120) were randomly divided into three groups according to enamel treatment (n=40 each): (1) enamel without restoration (control); (2) enamel cavities (3 mm diameter × 1.5 mm depth) restored with a silorane-based (SB) system; or (3) enamel cavities (3 mm diameter × 1.5 mm depth) restored with a dimethacrylate-based (DB) system...
November 28, 2016: Operative Dentistry
https://www.readbyqxmd.com/read/27884690/conditioned-pain-modulation-and-pressure-pain-sensitivity-in-the-adult-danish-general-population-the-danfund-study
#6
S Skovbjerg, T Jørgensen, L Arendt-Nielsen, J F Ebstrup, T Carstensen, T Graven-Nielsen
: Increased pressure pain sensitivity and impaired descending pain control have been associated with chronic pain, but knowledge on the variability in the adult general population is lacking. Pressure pain thresholds (PPTs) and descending pain control as assessed by conditioning pain modulation (CPM) were recorded in a randomly selected sample (n=2199, 53% females) of the Danish adult general population aged 18-70 years. PPTs were recorded over the tibialis anterior muscle and the upper trapezius muscle...
November 21, 2016: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/27882777/real-time-visual-activity-feedback-for-physical-activity-improvement-in-breast-and-colon-cancer-patients
#7
Lars Gabrys, Stefan Sperzel, Marcus Bernhoerster, Winfried Banzer, Lutz Vogt
The study aims to evaluate the effects and feasibility of a biofeedback device for physical activity (PA) improvement in breast and colon cancer patients. Daily PA of 19 cancer patients was measured by accelerometry (ActiGraph, GT1 M). Additionally, patients wore a motion sensor with real-time visual activity feedback (ActiSmile). Counts per minutes (cpm) and moderate to vigorous physical activity (MVPA) were calculated and patients' activity data were compared to PA of 20 age-matched healthy controls. Baseline PA of patients was lower compared to controls...
November 24, 2016: Research in Sports Medicine
https://www.readbyqxmd.com/read/27882183/psychiatric-symptoms-and-limb-tremors-associated-with-central-pontine-myelinolysis-a-case-of-alcoholism-without-hyponatremia
#8
Xue-Min Feng, Teng Zhao, Chun-Kui Zhou, Jing-Yao Liu
Central pontine myelinolysis (CPM), also known as osmotic demyelination syndrome, is a rare demyelinating disorder characterized by the loss of myelin in the center of the basis pontis. In this case report, an alcoholic patient with CPM and acquired demyelinating lesion of the basis pontis is described. The patient is a 70 year-old woman who presented with intermittent psychiatric symptoms and limb tremors following two months of alcohol abuse. During admission, magnetic resonance imaging (MRI) revealed hyperintensity on T2 weighted images and fluid-attenuated inversion-recovery imaging in the central pons without contrast enhancement...
November 2016: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/27882029/effects-of-comprehensive-rehabilitation-training-in-combination-with-multi-mode-analgesia-on-body-function-recovery-after-tumor-type-knee-replacement
#9
Junjuan Zhang, Yahan Wang, Guangyu Yang, Jing Liu, Junjie Wang
OBJECTIVE: To discuss the significance of comprehensive rehabilitation training combined with multimodal analgesia (MMA) for the early knee function recovery of patients with knee bone tumor who underwent prosthesis replacement operation. METHODS: Sixty patients with knee bone tumor who underwent prosthesis replacement operation were selected and randomly divided into two groups according to rehabilitation training and postoperative analgesic methods, namely, observation group and control group, 30 cases in each group...
September 2016: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/27866822/correlates-of-physical-activity-among-young-children-with-moderate-acute-malnutrition
#10
Charles W Yaméogo, Bernardette Cichon, Christian Fabiansen, Ann-Sophie Iuel-Brockdorf, Susan Shepherd, Suzanne Filteau, Alfred S Traoré, Vibeke B Christensen, Kim F Michaelsen, Soren Brage, Henrik Friis, Daniel Faurholt-Jepsen
OBJECTIVE: To assess the levels of physical activity among young children with moderate acute malnutrition and to identify clinical, biochemical, anthropometric, and sociodemographic correlates of physical activity. STUDY DESIGN: In a cross-sectional study, 1609 children aged 6-23 months wore a triaxial accelerometer (ActiGraph GT3x+; ActiGraph, Pensacola, Florida) for 6 consecutive days, from which total physical activity were determined. Data on morbidity were collected based by history and physical examination, and serum C-reactive protein and α1-acid glycoprotein were measured...
November 18, 2016: Journal of Pediatrics
https://www.readbyqxmd.com/read/27865440/hemoglobin-of-12-g-dl-and-above-is-not-associated-with-increased-cardiovascular-morbidity-in-children-on-hemodialysis
#11
Michelle N Rheault, Julia T Molony, Thomas Nevins, Charles A Herzog, Blanche M Chavers
In adults on chronic hemodialysis, achieving a hemoglobin concentration of 12g/dl and above with erythropoiesis stimulating agents leads to increased cardiovascular events and mortality, but this may not be true in children. Therefore, we conducted a retrospective cohort study of pediatric patients (under 18) from the Centers for Medicare and Medicaid Services End Stage Renal Disease (ESRD) Clinical Performance Measures (CPM) project (2000 to 2008) merged with the United States Renal Data System. Hemoglobin was determined from the Clinical Performance Measures data, and beginning annually on January 1st of the next year, patients were followed for up to 1 year...
November 16, 2016: Kidney International
https://www.readbyqxmd.com/read/27864747/surgical-management-of-metastatic-colorectal-cancer-a-single-centre-experience-on-oncological-outcomes-of-pulmonary-resection-vs-cytoreductive-surgery-and-hipec
#12
Evelyn Yi Ting Wong, Grace Hwei Ching Tan, Deanna Wan Jie Ng, Tina Puay Theng Koh, Mrinal Kumar, Melissa Ching Ching Teo
PURPOSE: Metastasectomy is accepted as standard of care for selected patients with colorectal pulmonary metastases (CLM); however, the role of cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) for colorectal peritoneal metastases (CPM) is not universally accepted. We aim to compare oncological outcomes of patients with CLM and CPM after pulmonary resection and CRS-HIPEC, respectively, by comparing overall survival (OS) and disease-free survival (DFS). METHODS: A retrospective review of 49 CLM patients who underwent pulmonary resection, and 52 CPM patients who underwent CRS-HIPEC in a single institution from January 2003 to March 2015, was performed...
November 19, 2016: Journal of Gastrointestinal Cancer
https://www.readbyqxmd.com/read/27862179/the-use-of-a-battery-of-pain-models-to-detect-analgesic-properties-of-compounds-a-two-part-four-way-crossover-study
#13
P Okkerse, G van Amerongen, M L de Kam, J Stevens, R P Butt, R Gurrell, A Dahan, J M van Gerven, J L Hay, G J Groeneveld
AIM: The aim was to investigate the ability of a battery of pain models to detect analgesic properties of commonly used analgesics in healthy subjects. METHODS: The battery consisted of tests eliciting electrical, mechanical and thermal (contact heat and cold pressor)-pain and included a UVB model, the thermal grill illusion and a paradigm of conditioned pain modulation. Subjects were administered fentanyl 3 µg/kg, phenytoin 300 mg, (S)-ketamine 10 mg and placebo (part I), or imipramine 100 mg, pregabalin 300 mg, ibuprofen 600 mg and placebo (part II)...
November 9, 2016: British Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/27859944/user-independent-assessment-of-conditioning-pain-modulation-by-cuff-pressure-algometry
#14
T Graven-Nielsen, M Izumi, K K Petersen, L Arendt-Nielsen
BACKGROUND: The use of conditioning pain modulation (CPM) is hampered by poor reproducibility and lack of user-independent paradigms. This study refined the CPM paradigm by applying user-independent cuff algometry. METHODS: In 20 subjects, the CPM effect of conditioning with cuff stimulation on the arm was investigated by pain test stimuli on the contralateral leg before and in parallel with different cuff conditionings (10, 30, 60 kPa/60 s; 30, 60 kPa/10 s)...
November 11, 2016: European Journal of Pain: EJP
https://www.readbyqxmd.com/read/27854093/posterior-reversible-encephalopathy-syndrome-mimicking-brainstem-infarction-a-dilemma
#15
Tsung-Han Ho, Chia-Lin Tsai, Yaw-Don Hsu, Jiunn-Tay Lee, Fu-Chi Yang, Chia-Ching Hsu, Chun-Chieh Lin
PURPOSE: We had recently reported one case at American Journal of Emergency Medicine about centralvariant posterior reversible encephalopathy syndrome (PRES) in an 84-year-old woman with an initial misdiagnosis as central pontine myelinolysis (CPM). Here, we introduce another case of centralvariant PRES in a 49-year-old man mimicking as acute brainstem infarction in the cranial computed tomography (CT) findings. CASE REPORT: A 49-year-old man was admitted to the emergency department with a 5-day history of vertigo, cognitive decline, and difficulty in walking...
June 15, 2016: Acta Neurologica Taiwanica
https://www.readbyqxmd.com/read/27843758/frequency-and-duration-of-physical-activity-bouts-in-school-aged-children-a-comparison-within-and-between-days
#16
Hannah L Brooke, Andrew J Atkin, Kirsten Corder, Soren Brage, Esther Mf van Sluijs
Understanding how physical activity (PA) patterns vary within and between days may guide PA promotion in young people. We aimed to 1) describe and compare the frequency (bouts/day) and duration (min/bout) of bouts of moderate-to-vigorous intensity PA (MVPA) on weekdays vs. weekends and in-school vs. out-of-school, and 2) assess associations of bout frequency and duration in these time-segments with overall PA. We used cross-sectional accelerometer data from 2737 children (aged 6-19 years) in the United States National Health and Nutrition Examination Survey (NHANES) 2003-2006...
December 2016: Preventive Medicine Reports
https://www.readbyqxmd.com/read/27842888/cancer-precision-medicine-from-cancer-screening-to-drug-selection-and-personalized-immunotherapy
#17
REVIEW
Xiaolan Deng, Yusuke Nakamura
With the accelerating progress in basic and clinical cancer research, a huge body of new discoveries and powerful technologies has allowed us to implement a 'Cancer Precision Medicine (CPM)' system for cancer patients. The CPM system covers a wide range of cancer management including cancer screening, monitoring of relapse/recurrence, selection/prediction of effective drugs/treatments, and personalized immunotherapy. In this system individual cancer patients expect to receive personalized care: an appropriate dose of the right drug at the right time...
November 11, 2016: Trends in Pharmacological Sciences
https://www.readbyqxmd.com/read/27842482/antibiotic-release-from-calcium-phosphate-materials-in-oral-and-maxillofacial-surgery-molecular-cellular-and-pharmaceutical-aspects
#18
Angel Manchon, Juan Carlos Prados-Frutos, Carmen Rueda Rodriguez, Carmen Salinas Goodier, Mohammad Hadman Alkhraisat, Rosa Rojo, Arantza Rodriguez Gonzalez, Ana Berlanga, Enrique Lopez Cabarcos
Calcium phosphate materials (CPM) are widely used in dentistry and maxillofacial surgery. The presence of microbial biofilms and external infections are responsible for the failure of many procedures of dental implants and bone grafts. In an attempt to reduce the percentage of these infectious processes antibiotics have been associated with CPM improving certain conditions. For instance antibiotics administered orally or intravenously have less effect and the blood flow in relation to this is poor near implants and grafts...
November 14, 2016: Current Pharmaceutical Biotechnology
https://www.readbyqxmd.com/read/27831907/randomised-crossover-trial-of-rate-feedback-and-force-during-chest-compressions-for-paediatric-cardiopulmonary-resuscitation
#19
Rachael Kathleen Gregson, Tim James Cole, Sophie Skellett, Emmanouil Bagkeris, Denise Welsby, Mark John Peters
OBJECTIVE: To determine the effect of visual feedback on rate of chest compressions, secondarily relating the forces used. DESIGN: Randomised crossover trial. SETTING: Tertiary teaching hospital. SUBJECTS: Fifty trained hospital staff. INTERVENTIONS: A thin sensor-mat placed over the manikin's chest measured rate and force. Rescuers applied compressions to the same paediatric manikin for two sessions...
October 24, 2016: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/27815748/a-model-for-individualized-risk-prediction-of-contralateral-breast-cancer
#20
Marzana Chowdhury, David Euhus, Tracy Onega, Swati Biswas, Pankaj K Choudhary
PURPOSE: Patients diagnosed with invasive breast cancer (BC) or ductal carcinoma in situ are increasingly choosing to undergo contralateral prophylactic mastectomy (CPM) to reduce their risk of contralateral BC (CBC). This is a particularly disturbing trend as a large proportion of these CPMs are believed to be medically unnecessary. Many BC patients tend to substantially overestimate their CBC risk. Thus, there is a pressing need to educate patients effectively on their CBC risk. We develop a CBC risk prediction model to aid physicians in this task...
November 4, 2016: Breast Cancer Research and Treatment
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