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https://www.readbyqxmd.com/read/29338639/is-continuous-passive-motion-effective-in-patients-with-lymphedema-a-randomized-controlled-trial
#1
Ramazan Kizil, Banu Dilek, Ebru Şahin, Onur Engin, Ali Can Soylu, Elif Akalin, Serap Alper
BACKGROUND: In this randomized controlled study, we aimed to evaluate the effect of shoulder flexion exercise using continuous passive motion (CPM) on lymphedema during the treatment of breast cancer-related lymphedema (BCRL). METHODS: Thirty patients with BCRL were enrolled and completed the study. Fourteen patients were treated with complete decongestive therapy (CDT) and CPM in the intervention group, and 16 patients were treated with CDT alone (control group) for 15 sessions...
January 17, 2018: Lymphatic Research and Biology
https://www.readbyqxmd.com/read/29327392/differences-in-white-matter-structure-and-cortical-thickness-between-patients-with-traumatic-and-idiopathic-chronic-neck-pain-associations-with-cognition-and-pain-modulation
#2
I Coppieters, R De Pauw, K Caeyenberghs, D Lenoir, K DeBlaere, E Genbrugge, M Meeus, B Cagnie
Brain alterations are hypothesized to be present in patients with chronic whiplash-associated disorders (CWAD). The aim of this case-control study was to examine alterations in cortical thickness and white matter (WM) structure, and the presence of brain microhemorrhages in a patient group encountering chronic neck pain of traumatic origin (i.e., CWAD) when compared with a patient group characterized by nontraumatic chronic neck pain [i.e., chronic idiopathic neck pain (CINP)], and healthy controls. Furthermore, we aimed to investigate associations between brain structure on one hand and cognitive performance and central sensitization (CS) on the other hand...
January 11, 2018: Human Brain Mapping
https://www.readbyqxmd.com/read/29318430/an-eight-year-prospective-controlled-study-about-the-safety-and-diagnostic-value-of-cardiac-and-non-cardiac-1-5-t-mri-in-patients-with-a-conventional-pacemaker-or-a-conventional-implantable-cardioverter-defibrillator
#3
Pierpaolo Lupo, Riccardo Cappato, Giovanni Di Leo, Francesco Secchi, Giacomo D E Papini, Sara Foresti, Hussam Ali, Guido M G De Ambroggi, Antonio Sorgente, Gianluca Epicoco, Paola M Cannaò, Francesco Sardanelli
OBJECTIVES: To investigate safety and diagnostic value of 1.5-T MRI in carriers of conventional pacemaker (cPM) or conventional implantable defibrillator (cICD). METHODS: We prospectively compared cPM/cICD-carriers undergoing MRI (study group, SG), excluding those device-dependent or implanted <6 weeks before enrolment or prior to 01/01/2000, with cPM/cICD-carriers undergoing chest x-ray, CT or follow-up (reference group, RG). RESULTS: 142 MRI (55 cardiac) were performed in 120 patients with cPM (n=71) or cICD (n=71)...
January 9, 2018: European Radiology
https://www.readbyqxmd.com/read/29315149/cohesive-polydensified-matrix-hyaluronic-acid-for-the-treatment-of-etched-in-fine-facial-lines-a-6-month-open-label-clinical-trial
#4
Jeanette M Black, Todd M Gross, Crystal L Murcia, Derek H Jones
BACKGROUND: Available hyaluronic acid dermal fillers have unique biophysical properties that influence their clinical utility, longevity, and aesthetic outcomes. OBJECTIVE: To evaluate the effectiveness and durability of a cohesive polydensified matrix hyaluronic acid dermal filler (CPM-HA) for the treatment of etched-in fine facial lines. MATERIALS AND METHODS: Subjects with etched-in fine lines of the forehead, cutaneous lip, melolabial folds, nasolabial folds, and/or radial cheek received treatment with CPM-HA mixed with lidocaine and epinephrine, with an optional touch-up treatment at Week 2, if deemed necessary...
January 8, 2018: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/29314741/a-bench-study-of-inhaled-nitric-oxide-delivery-during-high-frequency-percussive-ventilation
#5
Richard D Branson, Jeff Griebel, Dario Rodriquez
BACKGROUND: Safe and effective delivery of inhaled nitric oxide (INO) requires the appropriate interface of ventilator and INO delivery device. METHODS: We compared INO delivery using four configurations with the Transport Sinusoidal Bronchotron® and INOmax DSIR Plus® in a lung model. Ventilator settings and lung model values were held constant. Delivered NO, NO2 , and inspired oxygen (FIO2 ) were measured. The mean difference between set and measured NO was calculated and compared using ANOVA...
January 4, 2018: Pediatric Pulmonology
https://www.readbyqxmd.com/read/29297211/pupil-size-stability-of-the-cubic-phase-mask-solution-for-presbyopia
#6
Citlalli Almaguer, Eva Acosta, Justo Arines
Presbyopia correction involves different types of studies such as lens design, clinical study, and the development of objective metrics, such as the visual Strehl ratio. Different contact lens designs have been proposed for presbyopia correction, but performance depends on pupil diameter. We will analyze the potential use of a nonsymmetrical element, a cubic phase mask (CPM) solution, to develop a contact or intraocular lens whose performance is nearly insensitive to changes in pupil diameter. We will show the through focus optical transfer function of the proposed element for different pupil diameters ranging from 3 to 7 mm...
January 2018: Journal of Biomedical Optics
https://www.readbyqxmd.com/read/29291444/an-improved-99mtc-hynic-ser-3-ltvspwy-peptide-with-edda-tricine-as-co-ligands-for-targeting-and-imaging-of-her2-overexpression-tumor
#7
Fatemeh Khodadust, Sajjad Ahmadpour, Nazan Aligholikhamseh, Seyed Mohammad Abedi, Seyed Jalal Hosseinimehr
Overexpression of human epidermal receptor 2 (HER2) has given the opportunity for targeting and delivering of imaging radiotracers. The aim of this study was to evaluate the 99mTc-HYNIC-(EDDA/tricine)-(Ser)3-LTVSPWY peptide for tumor targeting and imaging of tumor with overexpression of HER2. The HYNIC-(Ser)3-LTVSPWY was labeled with 99mTc in presence of EDDA/tricine mixture as co-ligands. The in vitro and in vivo studies of this radiolabeled peptide were performed for cellular specific binding and tumor targeting...
December 13, 2017: European Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/29288475/cancer-pain-management-at-oncology-units-comparing-knowledge-attitudes-and-perceived-barriers-between-physicians-and-nurses
#8
Muhammad Darawad, Malek Khalel Alnajar, Maysoon S Abdalrahim, Aqel Mohammad El-Aqoul
Pain is a major symptom that causes suffering among patients diagnosed with cancer. Identifying physicians' and nurses' knowledge, attitudes, and their perceived barriers of cancer pain management is considered an essential step in improving cancer pain relief. The purposes of this study are to compare physicians' and nurses' knowledge and attitudes toward cancer pain management (CPM) and describe their perceived barriers to CPM at oncology units. A descriptive cross-sectional design was utilized to obtain data through self-report questionnaire...
December 29, 2017: Journal of Cancer Education: the Official Journal of the American Association for Cancer Education
https://www.readbyqxmd.com/read/29288115/mastectomy-for-risk-reduction-or-symmetry-in-women-without-high-risk-gene-mutation-a-review
#9
REVIEW
R Kenny, M Reed, A Subramanian
BACKGROUND: Prophylactic or 'risk-reducing' mastectomy refers to the procedure of completely removing a healthy breast in order to reduce the risk of developing breast cancer. This may be bilateral or may be performed to the contralateral breast as part of the treatment of a proven breast cancer. The rate of this procedure being performed has been shown to be increasing over the last two decades. Recent guidance for Breast clinicians has been issued over the last 12 months by both The Association of Breast Surgery of Great Britain and Ireland (ABSGBI) and the American Society of Breast Surgeons (ASBrS)...
December 26, 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/29282326/neurocognitive-functioning-and-cerebrovascular-reactivity-after-carotid-endarterectomy
#10
Simona Lattanzi, Luciano Carbonari, Gabriele Pagliariccio, Marco Bartolini, Claudia Cagnetti, Giovanna Viticchi, Laura Buratti, Leandro Provinciali, Mauro Silvestrini
OBJECTIVE: To evaluate in patients with TIA and ipsilateral high-grade internal carotid artery (ICA) stenosis whether changes in cognitive performance and cerebral hemodynamics occurred after carotid endarterectomy (CEA) and to explore their relationship. METHODS: Participants were patients who underwent CEA, had TIA within the last 6 months, and had an ipsilateral severe ICA stenosis. Coloured Progressive Matrices (CPM) plus Complex Figure Copy Test (CFCT) and phonemic (ph) plus categorical (ca) Verbal Fluency (VF) tests were performed to assess right and left hemisphere cognitive functions, respectively...
December 27, 2017: Neurology
https://www.readbyqxmd.com/read/29280482/national-trends-in-primary-tracheoesophageal-puncture-after-total-laryngectomy
#11
Rosh K V Sethi, Daniel G Deschler
OBJECTIVES/HYPOTHESIS: Tracheoesophageal puncture (TEP) can be performed at the time of laryngectomy (primary) or postoperatively (secondary). Prior studies demonstrate safe and earlier voice acquisition and rehabilitation with primary TEP. The objectives of this study were to assess national trends in primary TEP and identify factors associated with its use. STUDY DESIGN: Retrospective review. METHODS: Retrospective analysis of the Nationwide Inpatient Sample (NIS) from 2010 to 2014 was performed...
December 27, 2017: Laryngoscope
https://www.readbyqxmd.com/read/29276401/cohesive-polydensified-matrix%C3%A2-hyaluronic-acid-volumizer-injected-for-cheek-augmentation-has-additional-positive-effect-on-nasolabial-folds
#12
Gerd Gauglitz, Stephanie Steckmeier, Julian Pötschke, Hannah Schwaiger
Purpose: Cohesive Polydensified Matrix® hyaluronic acid (CPM-HA) volumizer has been used successfully for several years to reverse biometric volume loss during facial aging. This observational study explored the additive effect on nasolabial folds when CPM-HA volumizer is injected into the neighboring cheek area. Patients and methods: In this open-label, prospective, postmarketing noninterventional study, 18 adult patients seeking esthetic enhancement of the lateral cheek hollows and cheekbone area were injected with CPM-HA volumizer integrated with lidocaine (CPM-HA-VL) in the upper or lower cheek area...
2017: Clinical, Cosmetic and Investigational Dermatology
https://www.readbyqxmd.com/read/29251681/rising-rates-of-contralateral-prophylactic-mastectomy-as-a-treatment-for-early-stage-breast-cancer
#13
Bonnie Jerome-DʼEmilia, Debashis Kushary, Patricia D Suplee
BACKGROUND: The rate of contralateral prophylactic mastectomy (CPM) in women with unilateral mastectomy is increasing with no plateau. OBJECTIVES: The aim of this study was to improve the understanding of patient- and tumor-related factors that influenced the choice of mastectomy with CPM as treatment for early-stage breast cancer at an academic medical center in New Jersey. METHODS: This was a retrospective analysis of 10 years of breast cancer data including 1556 women aged 40 to 80 years treated for breast cancer at an academic medical center...
December 14, 2017: Cancer Nursing
https://www.readbyqxmd.com/read/29250812/a-multiple-model-generalisation-of-updating-clinical-prediction-models
#14
Glen P Martin, Mamas A Mamas, Niels Peek, Iain Buchan, Matthew Sperrin
There is growing interest in developing clinical prediction models (CPMs) to aid local healthcare decision-making. Frequently, these CPMs are developed in isolation across different populations, with repetitive de novo derivation a common modelling strategy. However, this fails to utilise all available information and does not respond to changes in health processes through time and space. Alternatively, model updating techniques have previously been proposed that adjust an existing CPM to suit the new population, but these techniques are restricted to a single model...
December 18, 2017: Statistics in Medicine
https://www.readbyqxmd.com/read/29243785/induction-of-proliferation-and-activation-of-rat-hepatic-stellate-cells-via-high-glucose-and-high-insulin
#15
Q Li, X Li, C-L Deng
OBJECTIVE: To further investigate the occurrence mechanism of diabetic hepatic fibrosis through observing the effects of insulin and glucose in different concentrations on hepatic stellate cell (HSC) proliferation, and mRNA expressions of transforming growth factor-β1 (TGF-β1) and tissue inhibitor of metalloproteinase-1 (TIMP-1) in rats, so as to provide a theoretical and experimental basis for the occurrence, prevention and treatment of diabetic hepatic fibrosis (HF). MATERIALS AND METHODS: The HSCs in rats were cultured in vitro with high glucose alone and high glucose + high insulin as the stimulating factors and mannitol as the high osmotic pressure control...
December 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29241836/opposite-effects-of-stress-on-pain-modulation-depend-on-the-magnitude-of-individual-stress-response
#16
Nirit Geva, Ruth Defrin
The effect of acute stress on pain threshold and intolerance threshold are reported as producing either hypoalgesia or hyperalgesia. Yet, the contribution of individual stress reactivity in this respect has not been established. The aim was to test two pain modulation paradigms under acute stress manipulation, here for the first time, in order to study whether stress differentially affects pain modulation, and whether the effect is related to individual stress response. Participants were 31 healthy subjects...
December 11, 2017: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/29236339/physical-activity-level-among-children-recovering-from-severe-acute-malnutrition
#17
Esther Babirekere-Iriso, Maren Johanne Heilskov Rytter, Hanifa Namusoke, Ezekiel Mupere, Kim F Michaelsen, Søren Brage, Ken D Stark, Lotte Lauritzen, André Briend, Henrik Friis, Daniel Faurholt-Jepsen
OBJECTIVE: To assess the level and predictors of physical activity at discharge among children recovering from severe acute malnutrition (SAM). METHODS: We conducted a prospective study among 69 children 6 - 59 months of age admitted with SAM for nutritional rehabilitation at Mulago National Referral Hospital, Uganda. Using hip-mounted tri-axial accelerometers, we measured physical activity expressed as counts per minute (cpm) during the last three days of hospital treatment...
December 13, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/29234460/generalized-enhanced-suffix-array-construction-in-external-memory
#18
Felipe A Louza, Guilherme P Telles, Steve Hoffmann, Cristina D A Ciferri
Background: Suffix arrays, augmented by additional data structures, allow solving efficiently many string processing problems. The external memory construction of the generalized suffix array for a string collection is a fundamental task when the size of the input collection or the data structure exceeds the available internal memory. Results: In this article we present and analyze [Formula: see text] [introduced in CPM (External memory generalized suffix and [Formula: see text] arrays construction...
2017: Algorithms for Molecular Biology: AMB
https://www.readbyqxmd.com/read/29228720/gastric-myoelectric-activity-during-cisplatin-induced-acute-and-delayed-emesis-reveals-a-temporal-impairment-of-slow-waves-in-ferrets-effects-not-reversed-by-the-glp-1-receptor-antagonist-exendin-9-39
#19
Zengbing Lu, Man P Ngan, Ge Lin, David T W Yew, Xiaodan Fan, Paul L R Andrews, John A Rudd
Preclinical studies show that the glucagon-like peptide-1 (GLP-1) receptor antagonist, exendin (9-39), can reduce acute emesis induced by cisplatin. In the present study, we investigate the effect of exendin (9-39) (100 nmol/24 h, i.c.v), on cisplatin (5 mg/kg, i.p.)-induced acute and delayed emesis and changes indicative of 'nausea' in ferrets. Cisplatin induced 37.2 ± 2.3 and 59.0 ± 7.7 retches + vomits during the 0-24 (acute) and 24-72 h (delayed) periods, respectively. Cisplatin also increased (P<0...
November 17, 2017: Oncotarget
https://www.readbyqxmd.com/read/29222950/tolerance-design-of-patient-specific-range-qa-using-the-dmaic-framework-in-proton-therapy
#20
Jeong-Eun Rah, Dongho Shin, Ryan P Manger, Tae Hyun Kim, Do Hoon Oh, Dae Yong Kim, Gwe-Ya Kim
PURPOSE: To implement the DMAIC (Define-Measure-Analyze-Improve-Control) can be used for customizing the patient-specific QA by designing site-specific range tolerances. METHODS: The DMAIC framework (process flow diagram, cause and effect, Pareto chart, control chart, and capability analysis) were utilized to determine the steps that need focus for improving the patient-specific QA. The patient-specific range QA plans were selected according to 7 treatment site groups, a total of 1437 cases...
December 9, 2017: Medical Physics
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