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https://www.readbyqxmd.com/read/29143174/single-cell-imaging-using-radioluminescence-microscopy-reveals-unexpected-binding-target-for-18f-hfb
#1
Louise Kiru, Tae Jin Kim, Bin Shen, Frederick T Chin, Guillem Pratx
PURPOSE: Cell-based therapies are showing great promise for a variety of diseases, but remain hindered by the limited information available regarding the biological fate, migration routes and differentiation patterns of infused cells in trials. Previous studies have demonstrated the feasibility of using positron emission tomography (PET) to track single cells utilising an approach known as positron emission particle tracking (PEPT). The radiolabel hexadecyl-4-[(18)F]fluorobenzoate ([(18)F]HFB) was identified as a promising candidate for PEPT, due to its efficient and long-lasting labelling capabilities...
November 15, 2017: Molecular Imaging and Biology: MIB: the Official Publication of the Academy of Molecular Imaging
https://www.readbyqxmd.com/read/29142418/marantodes-pumilum-blume-kuntze-inhibited-secretion-of-lipopolysaccharide-and-monosodium-urate-crystal-stimulated-cytokines-and-plasma-prostaglandin-e2
#2
Eldiza Puji Rahmi, Jamia Azdina Jamal, Endang Kumolosasi, Juriyati Jalil, Nor-Ashila Aladdin
Background: Marantodes pumilum is traditionally used for dysentery, gonorrhea, and sickness in the bones. Previous studies revealed its antibacterial and xanthine oxidase inhibitory activities. Objective: To evaluate the inhibitory effects of three M. pumilum varieties on the secretion of lipopolysaccharide (LPS)- and monosodium urate crystal (MSU)-induced cytokines and plasma prostaglandin E2 (PGE2) in vitro. Materials and Methods: The leaves and roots of M...
October 2017: Pharmacognosy Magazine
https://www.readbyqxmd.com/read/29142352/localized-pontine-uptake-in-fluorine-18-fuorodeoxyglucose-positron-emission-tomography-computed-tomography-in-a-case-of-hyponatremia-a-case-report-and-review-of-literature
#3
Thangalakshmi Sivathapandi, Shelley Simon, Indirani Elangovan
A rare acquired demyelinating lesion of the pons central pontine myelinolysis (CPM) typically occurs after rapid correction of hyponatremia. There is disruption of blood-brain barrier due to osmotic stress allowing access for inflammatory mediators in extravascular brain tissue, which most likely attracts glial cells of the brain, attracts macrophages, and activates astrocytes. We present a case of female with a known history of inflammatory bowel disease who presented with altered sensorium and hyponatremia...
October 2017: Indian Journal of Nuclear Medicine: IJNM: the Official Journal of the Society of Nuclear Medicine, India
https://www.readbyqxmd.com/read/29139299/integrating-zeolite-type-chalcogenide-with-titanium-dioxide-nanowires-for-enhanced-photoelectrochemical-activity
#4
Chengyu Mao, Yanxiang Wang, Wei Jiao, Xitong Chen, Qipu Lin, Mingli Deng, Yun Ling, Yaming Zhou, Xianhui Bu, Pingyun Feng
Developing photoanodes with efficient visible-light harvesting and excellent charge separation still remains a key challenge in photoelectrochemical water splitting. Here zeolite-type chalcogenide CPM-121 is integrated with TiO2 nanowires to form a heterostructured photoanode, in which crystalline CPM-121 particles serve as a visible light absorber and TiO2 nanowires serve as an electron conductor. Owing to the small band gap of chalcogenides, the hybrid electrode demonstrates obvious absorption in visible-light range...
November 15, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/29136315/deficient-pain-modulation-in-patients-with-a-chronic-hemiplegic-shoulder-pain
#5
Yafit Kashi, Motti Ratmansky, Ruth Defrin
BACKGROUND: Hemiplegic Shoulder Pain (HSP) following stroke significantly affects the individual's function and quality of life. The mechanism of HSP is not clearly understood, hence it is unclear why HSP resolves spontaneously or following routine care in some patients, while in others it becomes persistent. The aim was therefore, to study whether HSP is associated with deficient pain modulation. METHODS: Thirty post-stroke patients; 16 with HSP and 14 without HSP, and 20 matched controls participated...
November 14, 2017: Pain Practice: the Official Journal of World Institute of Pain
https://www.readbyqxmd.com/read/29129014/causal-factors-of-corruption-in-construction-project-management-an-overview
#6
REVIEW
Emmanuel Kingsford Owusu, Albert P C Chan, Ming Shan
The development of efficient and strategic anti-corruption measures can be better achieved if a deeper understanding and identification of the causes of corruption are established. Over the past years, many studies have been devoted to the research of corruption in construction management (CM). This has resulted in a significant increase in the body of knowledge on the subject matter, including the causative factors triggering these corrupt practices. However, an apropos systematic assessment of both past and current studies on the subject matter which is needful for the future endeavor is lacking...
November 11, 2017: Science and Engineering Ethics
https://www.readbyqxmd.com/read/29127715/relationship-between-preoperative-breast-mri-and-surgical-treatment-of-non-metastatic-breast-cancer
#7
Tracy Onega, Julie E Weiss, Martha E Goodrich, Weiwei Zhu, Wendy B DeMartini, Karla Kerlikowske, Elissa Ozanne, Anna N A Tosteson, Louise M Henderson, Diana S M Buist, Karen J Wernli, Sally D Herschorn, Elise Hotaling, Cristina O'Donoghue, Rebecca Hubbard
BACKGROUND AND OBJECTIVES: More extensive surgical treatments for early stage breast cancer are increasing. The patterns of preoperative MRI overall and by stage for this trend has not been well established. METHODS: Using Breast Cancer Surveillance Consortium registry data from 2010 through 2014, we identified women with an incident non-metastatic breast cancer and determined use of preoperative MRI and initial surgical treatment (mastectomy, with or without contralateral prophylactic mastectomy (CPM), reconstruction, and breast conserving surgery ± radiation)...
November 11, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29122785/naoxuekang-xinnaoshutong-and-xuesaitong-capsules-for-treating-stroke-a-protocol-for-a-randomised-controlled-trial
#8
Huiling Chen, Hongbo Cao, Xu Guo, Meidan Zhao, Qing Xia, Bo Chen, Tieniu Zhao, Wenyuan Gao
INTRODUCTION: After stroke, hemiplegia, dysphasia and facial paralysis can manifest during the convalescent period. Currently, no Chinese patent medicine (CPM) is previously reported to cure each of these symptoms primarily, and thus, there are no relevant instructions for the use of CPM. This study presents a new approach based on comparative effectiveness research to distinguish the curative effects of three CPMs that are often used in stroke convalescence to determine the ideal medicine for the treatment of each symptom...
November 8, 2017: BMJ Open
https://www.readbyqxmd.com/read/29122720/connectome-based-predictive-modeling-of-attention-comparing-different-functional-connectivity-features-and-prediction-methods-across-datasets
#9
Kwangsun Yoo, Monica D Rosenberg, Wei-Ting Hsu, Sheng Zhang, Chiang-Shan R Li, Dustin Scheinost, R Todd Constable, Marvin M Chun
Connectome-based predictive modeling (CPM; Finn et al., 2015; Shen et al., 2017) was recently developed to predict individual differences in traits and behaviors, including fluid intelligence (Finn et al., 2015) and sustained attention (Rosenberg et al., 2016a), from functional brain connectivity (FC) measured with fMRI. Here, using the CPM framework, we compared the predictive power of three different measures of FC (Pearson's correlation, accordance, and discordance) and two different prediction algorithms (linear and partial least square [PLS] regression) for attention function...
November 6, 2017: NeuroImage
https://www.readbyqxmd.com/read/29121785/psychometric-investigation-of-the-raven-s-colored-progressive-matrices-test-in-a-sample-of-preschool-children
#10
Patrícia Silva Lúcio, Hugo Cogo-Moreira, Marina Puglisi, Guilherme Vanoni Polanczyk, Todd D Little
The present study investigated the psychometric properties of the Raven's Colored Progressive Matrices (CPM) test in a sample of preschoolers from Brazil ( n = 582; age: mean = 57 months, SD = 7 months; 46% female). We investigated the plausibility of unidimensionality of the items (confirmatory factor analysis) and differential item functioning (DIF) for sex and age (multiple indicators multiple causes method). We tested four unidimensional models and the one with the best-fit index was a reduced form of the Raven's CPM...
November 1, 2017: Assessment
https://www.readbyqxmd.com/read/29106478/physical-activity-and-frailty-among-older-adults-in-the-u-s-based-on-hourly-accelerometry-data
#11
Megan Huisingh-Scheetz, Kristen Wroblewski, Masha Kocherginsky, Elbert Huang, Dale William, Linda Waite, L Philip Schumm
Background/Objectives: Accelerometry measures older adult (in)activity with high resolution. Most studies summarize activity over the entire wear time. We extend prior work by analyzing hourly activity data to determine how frailty and other characteristics relate to activity among older adults. Methods: Using wrist accelerometry data collected from the National Social Life, Health and Aging Project (n=651), a nationally-representative probability sample of older adults, we used mixed effects linear regression to model the logarithm of hourly counts per minute (CPM) as a function of an adapted phenotypic frailty score, adjusting for demographic and health characteristics, season, day of week and time of day...
November 2, 2017: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/29095576/is-central-pontine-myelinolysis-reversible
#12
David Lee Rebedew
Central pontine myelinolysis (CPM) is a rare phenomenon that causes significant morbidity and mortality. Active therapeutic interventions for CPM can have a positive impact on recovery and overall prognosis. This case represents a 34-year-old white man with a chronic history of alcohol abuse who had Parkinsonian symptoms 13 days after rapid correction of his serum sodium in the hospital. Similarly to prior CPM case reports, this patient significantly improved following reinduction of hyponatremia, methylprednisolone, and/or plasmapharesis...
December 2016: WMJ: Official Publication of the State Medical Society of Wisconsin
https://www.readbyqxmd.com/read/29090288/theoretical-study-on-the-gas-adsorption-capacity-and-selectivity-of-cpm-200-in-mg-and-cpm-200-in-mg-x-x-nh2-oh-n-f
#13
Xiao-le Liu, Guang-Hui Chen, Xiu-Jun Wang, Peng Li, Yi-Bing Song, Rui-Yan Li
The adsorption capacities of a heterometallic metal-organic framework (CPM-200-In/Mg) to VOCs (HCHO, C2H4, CH4, C2H2, C3H8, C2H6, C2H3Cl, C2H2Cl2, CH2Cl2 and CHCl3) and some inorganic gas molecules (HCN, SO2, NO, CO2, CO, H2S and NH3), as well as its selectivity in ternary mixture systems of natural gas and post-combustion flue gas are theoretically explored at the grand canonical Monte Carlo (GCMC) and density functional theory (DFT) levels. It is shown that CPM-200-In/Mg is suitable for the adsorption of VOCs, particularly for HCHO (up to 0...
November 1, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/29083513/swallowing-outcomes-after-cricopharyngeal-myotomy-a-systematic-review
#14
Molly A Knigge, Susan L Thibeault
BACKGROUND: No practice guidelines have been established for swallowing outcomes after cricopharyngeal myotomy (CPM). The purpose of this systematic review was to summarize evidence for swallowing outcomes in patients undergoing CPM to treat symptomatic cricopharyngeal dysfunction, in accordance with the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) protocol. METHODS: Swallowing outcomes examined included penetration/aspiration ratings, manometric measures, patient-rated dysphagia scales, clinician-rated dysphagia scales, diet level, and weight...
October 30, 2017: Head & Neck
https://www.readbyqxmd.com/read/29081683/physical-activity-may-be-associated-with-conditioned-pain-modulation-in-women-but-not-men-among-healthy-individuals
#15
Yukiko Shiro, Tatsunori Ikemoto, Yuta Terasawa, Young-Chang P Arai, Kazuhiro Hayashi, Takahiro Ushida, Takako Matsubara
BACKGROUND: Conditioned pain modulation (CPM), a phenomenon also known as diffuse noxious inhibitory control, is thought to be affected by various factors, including sex and level of physical activity. However, the involvement of these factors in CPM remains unclear. METHODS: Eighty-six healthy young subjects (M/F, 43/43) participated in this study. Participants were assessed on the basis of their mechanical pressure pain threshold (PPT), CPM response, body mass index (BMI), basal metabolic rate (BMR), and duration of moderate-to-vigorous physical activity (MVPA) over a week, using a motion counter...
2017: Pain Research & Management: the Journal of the Canadian Pain Society
https://www.readbyqxmd.com/read/29080928/clinical-long-term-success-of-contemporary-nano-filled-resin-composites-in-class-i-and-ii-restorations-cured-by-led-or-halogen-light
#16
Torsten Pflaum, Stefan Kranz, Regina Montag, Arndt Güntsch, Andrea Völpel, Robin Mills, Klaus Jandt, Bernd Sigusch
OBJECTIVES: The use of LED light-curing units (LED LCUs) for polymerising resin-based composite restorations has become widespread throughout dentistry. Unfortunately, there is a paucity of clinical longitudinal studies that evaluate the comparative efficacy of LED-based polymerisation in direct posterior composite restorations. The aim of the present study was to investigate the performance of class I and II resin composite restorations for two successful composite restorative materials cured with LED versus halogen LCUs...
October 28, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/29080492/stability-indicating-hplc-dad-method-for-analysis-of-ketorolac-binary-and-ternary-mixtures-in-eye-drops-quantitative-analysis-in-rabbit-aqueous-humor
#17
Fawzy A El Yazbi, Ekram M Hassan, Essam F Khamis, Marwa A A Ragab, Mohamed M A Hamdy
Ketorolac tromethamine (KTC) with phenylephrine hydrochloride (PHE) binary mixture (mixture 1) and their ternary mixture with chlorpheniramine maleate (CPM) (mixture 2) were analyzed using a validated HPLC-DAD method. The developed method was suitable for the in vitro as well as quantitative analysis of the targeted mixtures in rabbit aqueous humor. The analysis in dosage form (eye drops) was a stability indicating one at which drugs were separated from possible degradation products arising from different stress conditions (in vitro analysis)...
October 14, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/29079906/a-summary-and-evaluation-of-current-evidence-for-myocardial-infarction-with-chinese-medicine
#18
Yue Wang, Lu Xiao, Wei Mu, Hai-Long Yu, Shuo Zhang, Gui-Hua Tian, Hong-Cai Shang
OBJECTIVE: To provide evidence-based recommendations for clinical application and provoke thoughts for future researchers by conducting a comprehensive summary and evaluation of the current evidence profifile for the role of Chinese medicine (CM) in treating myocardial infarction (MI). METHODS: Online databases including PubMed, EMBase, Cochrane Library, Chinese National Knowledge Infrastructure (CNKI), Chinese Biomedical Medicine (CBM), VIP Journal Integration Platform, and Wanfang database were systematically searched for literatures on CM in treating MI...
October 27, 2017: Chinese Journal of Integrative Medicine
https://www.readbyqxmd.com/read/29064771/contralateral-prophylactic-mastectomy-a-qualitative-approach-to-exploring-the-decision-making-process
#19
Judith R Greener, Sarah Bauerle Bass, Stephen J Lepore
The proportion of women with unilateral breast cancer and no familial or genetic risk factors who elect contralateral prophylactic mastectomy (CPM) has grown dramatically, even in the absence of clear data demonstrating improved outcomes. To further extend the literature that addresses treatment decision-making, qualitative interviews were conducted with eleven women who considered CPM. A social ecological model of breast cancer treatment decision-making provided the conceptual framework, and grounded theory was used to identify the cognitive, psychosocial, and emotional influences motivating treatment choice...
October 24, 2017: Journal of Psychosocial Oncology
https://www.readbyqxmd.com/read/29059982/ambulatory-gastric-mucosal-slow-wave-recording-for-chronic-experimental-studies
#20
Niranchan Paskaranandavadivel, Timothy Angeli, Abigail Stocker, Lindsay McElmurray, Gregory O'Grady, Thomas Abell, Leo K Cheng
Dysrhythmic bioelectric slow wave activity have been implicated in major functional motility disorders such as gastroparesis and chronic unexplained nausea and vomiting, but its correlation to symptoms is still unclear. For patients with severe gastroparesis, high-frequency gastric stimulation is offered as a therapy in some centers. Temporary gastric electrical stimulation has also been proposed an approach to screen patients who would benefit from the implantation of a permanent stimulator. In this study we introduced novel methods for recording slow wave activity from the gastric mucosa during the entire temporary stimulation phase of 5 days, in 3 patients...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
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