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Reverse dipping

Cheng Wang, Zengchun Ye, Yan Li, Jun Zhang, Qunzi Zhang, Xinxin Ma, Hui Peng, Tanqi Lou
The "reverse dipping" blood pressure (BP) pattern has been studied among the general population and in individuals suffering from hypertension. However, the prognosis of this pattern in chronic kidney disease (CKD) patients is not known. We monitored BP throughout the day and followed health outcomes in 588 CKD patients admitted to our hospital. Time to all-cause mortality, cardiovascular mortality, renal events and cardiovascular events was recorded. Multivariate-adjusted Cox regression analyses were carried out to detect the prognostic value of a reverse dipping BP pattern...
October 7, 2016: Scientific Reports
Jie Wang, Bowen Zhu, Zhenzhong Hao, Fang Bo, Xiaolei Wang, Feng Gao, Yigang Li, Guoquan Zhang, Jingjun Xu
We report the experimental observation and theoretical analysis of thermo-optic effects in high-Q on-chip lithium-niobate (LN) microdisks. We find that the resonance transmission dip of a LN microdisk was broadened or compressed when the wavelength of the input laser was tuned to the shorter or the longer wavelengths at a wavelength sweeping speed of 4.8 pm/s. When the laser wavelength was shifted with a fast rate (4.8 nm/s), the tendencies of the change in the shape of the transmission dip reverse completely...
September 19, 2016: Optics Express
Ran-Hui Cha, Hajeong Lee, Jung Pyo Lee, Chun Soo Lim, Yon Su Kim, Sung Gyun Kim
OBJECTIVE: Blood pressure (BP) control is the most established practice for preventing the progression of chronic kidney disease (CKD). We examined the BP control and nocturnal dipping pattern change in hypertensive patients with CKD and its effects on target organ damages. DESIGN AND METHOD: We recruited 378 hypertensive CKD patients from 4 centers in Korea. They underwent office and ambulatory BP monitoring at the time of enrollment and 1 year after. High office and ambulatory BP was defined as > 140/90 mmHg and > 135/85 mmHg (daytime)/> 120/70 mmHg (nighttime), respectively...
September 2016: Journal of Hypertension
W Schellekens, N F Ramsey, R J A van Wezel, M Raemaekers
The human brain is thought to respond differently to novel versus predictable neural input. In human visual cortex, neural response amplitude to visual input might be determined by the degree of predictability. We investigated how fMRI BOLD responses in human early visual cortex reflect the anticipation of a single moving bar's trajectory. We found that BOLD signals decreased linearly from onset to offset of the stimulus trajectory. Moreover, decreased amplitudes of BOLD responses coincided with an increased initial dip as the stimulus moved along its trajectory...
September 9, 2016: NeuroImage
Vahid Nikoui, Sattar Ostadhadi, Pardis Azhand, Samira Zolfaghari, Shayan Amiri, Mehrdad Foroohandeh, Manijeh Motevalian, Ali Mohammad Sharifi, Azam Bakhtiarian
Evidence show that gamma-aminobutyric acid (GABA) receptors are involved in depression, so the aim of this study was to investigate the effect of nitrazepam as agonist of GABAA receptors on depression and curiosity in male mice and the role of potassium channel in antidepressant-like response. For this purpose, we studied the antidepressant-like properties of fluoxetine, nitrazepam, glibenclamide, and cromakalim by both forced swimming test (FST) and tail suspension test (TST). Animals were injected by various doses of nitrazepam (0...
September 9, 2016: European Journal of Pharmacology
Eoin O'Brien, Eamon Dolan
PURPOSE: This purpose of this article is to review the current recommendations for ambulatory blood pressure measurement (ABPM) and the use of ABPM in assessing treatment. METHODS: We review current international guidelines and undertake a critical review of evidence supporting the clinical use of ABPM in effectively managing antihypertensive drug treatment. FINDINGS: Current guidelines emphasize the diagnostic superiority of ABPM, mainly from the ability of the technique to identify sustained hypertension by allowing for the exclusion of white-coat hypertension and by demonstrating the presence of masked hypertension...
September 8, 2016: Clinical Therapeutics
Masoumeh Ghalkhani, Javad Beheshtian, Maryam Salehi
The electrochemical response of mebendazole (Meb), an anticancer and effective anthelmintic drug, was investigated using two different carbon nanostructured modified glassy carbon electrodes (GCE). Although, compared to unmodified GCE, both prepared modified electrodes improved the voltammetric response of Meb, the carbon nanotubes (CNTs) modified GCE showed higher sensitivity and stability. Therefore, the CNTs-GCE was chosen as a promising candidate for the further studies. At first, the electrochemical behavior of Meb was studied by cyclic voltammetry and differential pulse and square wave voltammetry...
December 1, 2016: Materials Science & Engineering. C, Materials for Biological Applications
Monica Maselli, Valter Giantin, Alessandro Franchin, Francesca Attanasio, Alessandra Tramontano, Pietro De Toni, Valentina Pengo, Domenico Corrado, Enzo Manzato
INTRODUCTION: Little is known about the effects of atrial fibrillation (AF) on blood pressure (BP) levels in hypertensive patients. Some studies suggest a role for rhythm control in managing such patients' BP, but the improvement observed in cardiac performance after restoring sinus rhythm (SR) may coincide with an increase in BP. The aim of this study was to apply ambulatory BP monitoring to analyze BP changes in hypertensive patients after electrical cardioversion for persistent AF...
September 7, 2016: Blood Pressure Monitoring
Jin Han, Ya Gao, Qi Guo, Dan Su, Bin Yan, Liyuan Peng, Yuxing Du, Ke Li, Gang Wang
OBJECTIVE: To investigate the relationship between the level of serum cystatin C (s-CC) and reverse-dipper blood pressure (BP) pattern. DESIGN: Cross-sectional study. SETTING: Single centre. PARTICIPANTS: A total of 718 hypertensive patients were eventually recruited from cardiac clinics between 2012 and 2014 in the Second Affiliated Hospital, Xi'an Jiaotong University. They were diagnosed as essential hypertension according to their casual office records of systolic blood pressure (SBP) and/or diastolic blood pressure (DBP)...
2016: BMJ Open
Do Hong Kim, Dinsefa M Andoshe, Young-Seok Shim, Cheon-Woo Moon, Woonbae Sohn, Seokhoon Choi, Taemin Ludvic Kim, Migyoung Lee, Hoonkee Park, Kootak Hong, Ki Chang Kwon, Jun Min Suh, Jin-Sang Kim, Jong-Heun Lee, Ho Won Jang
Vertically ordered hematite nanotubes are considered to be promising photoactive materials for high-performance water-splitting photoanodes. However, the synthesis of hematite nanotubes directly on conducting substrates such as fluorine-doped tin oxide (FTO)/glass is difficult to be achieved because of the poor adhesion between hematite nanotubes and FTO/glass. Here, we report the synthesis of hematite nanotubes directly on FTO/glass substrate and high-performance photoelectrochemical properties of the nanotubes with NiFe cocatalysts...
September 14, 2016: ACS Applied Materials & Interfaces
X-H Yin, Q-J Wu, Y-J Zhang, Y-H Long, X-M Wu, R-Y Li, M Wang, X-L Tian, X-G Jiao
A multi-generational approach was used to investigate the persistent effects of a sub-lethal dose of spinosad in Plutella xylostella. The susceptibility of various sub-populations of P. xylostella to spinosad and the effects of the insecticide on the gene expression of γ-aminobutyric acid receptor (GABAR) were determined. The results of a leaf dip bioassay showed that the sensitivity of P. xylostella to spinosad decreased across generations. The sub-strains had been previously selected based on a determined LC25 of spinosad...
2016: Genetics and Molecular Research: GMR
V Milazzo, C Di Stefano, F Vallelonga, G Sobrero, A Milan, M Zibetti, M Sarchioto, A Romagnolo, L Lopiano, F Veglio, S Maule
OBJECTIVE: Patients with Autonomic Neuropathy (AN) are characterized by orthostatic hypotension (OH), supine hypertension, high blood pressure (BP) variability and reverse dipping pattern on 24 h Ambulatory Blood Pressure Monitoring (24 h ABPM). AN is a common finding in Parkinson's disease (PD), and it is related to a higher motor impairment due to neurogenic OH. Aim of the study was the evaluation of the prevalence of AN and the assessment of the related 24 h ABPM profile in PD patients without known cardiovascular comorbidities...
September 2016: Journal of Hypertension
Zhongyun Liu, Yunxia Hu
Microbial attachment and biofilm formation on filtration membrane can greatly compromise its flux and separation efficiency. Here, a simple and facile approach has been developed to in situ generate silver nanoparticles (Ag NPs) on the thin film composite forward osmosis (TFC FO) membrane for sustainable antibiofouling performances. Mussel-inspired dopamine chemistry was applied to grow polydopamine coating on both surfaces of FO membranes, followed by the generation of Ag NPs upon a simple dip coating in silver nitrate aqueous solution...
August 24, 2016: ACS Applied Materials & Interfaces
Stefania L Magda, Raluca I Mincu, Stefan Dumitrache-Rujinski, Mircea Cinteza
Obstructive sleep apnea (OSA) has been included by European and American hypertension therapy guidelines as a common cause of high blood pressure. Recent studies have demonstrated a strong link between OSA and HBP and the treatment thereof should consist of combination therapy, especially in patients with refractory AHT and a non-dipping profile. We present the case of a patient with high grade hypertension, with secondary organ damage and severe OSA. The ultimate method for controlling blood pressure and reversing subclinical cardiac and cerebrovascular dysfunction of this patient was the specific therapy with continuous positive airway pressure (cPAP)...
October 2015: Pneumologia: Revista Societății Române de Pneumologie
Yanli Zhou, Ying Cheng, Yunqiang Yang, Xiong Li, Basak Supriyo, Xudong Sun, Yongping Yang
The purpose of the present study was to characterize SpCBL6 (GenBank accession number: KT780442) from Stipa purpurea and elucidate the function of this protein in abiotic stress. The full-length cDNA of SpCBL6 was isolated from S. purpurea by rapid amplification of cDNA ends methods. Laser confocal microscopy was used to analyze the subcellular localization of SpCBL6. The constructs of 35S:GFP-SpCBL6 was used to transform wild-type (WT) Arabidopsis plants (ecotype Columbia-0) with the floral dip method. Quantitative reverse-transcription PCR (qRT-PCR), water potential, photosynthetic efficiency (F v/F m), and ion leakage was performed to investigate the role of SpCBL6 in abiotic stress...
September 2016: Molecular Biology Reports
Manon Gault, Géraldine Effantin, Agnès Rodrigue
The biology of nickel has been widely studied in mammals because of its carcinogenic properties, whereas few studies have been performed in microorganisms. In the present work, changes accompanying stress caused by nickel were evaluated at the cellular level using RNA-Seq in Escherichia coli K-12. Interestingly, a very large number of genes were found to be deregulated by Ni stress. Iron and oxidative stress homeostasis maintenance were among the most highly enriched functional categories, and genes involved in periplasmic copper efflux were among the most highly upregulated...
August 2016: Free Radical Biology & Medicine
Moustafa Abdel Hafiz, Grégoire Coget, Emeric De Clercq, Rodolphe Boudot
We report on Doppler-free laser spectroscopy in a Cs vapor cell using a dual-frequency laser system tuned on the Cs D<sub>1</sub> line. Using counter-propagating beams with crossed linear polarizations, an original sign reversal of the usual saturated absorption dip and large increase in Doppler-free atomic absorption is observed. This phenomenon is explained by coherent population trapping (CPT) effects. The impact of laser intensity and light polarization on absorption profiles is reported in both single-frequency and dual-frequency regimes...
July 1, 2016: Optics Letters
M Y Goh, M S Millard, E C K Wong, D J Brown, A G Frauman, C J O'Callaghan
STUDY DESIGN: This is a prospective observational study. OBJECTIVES: The objective of this study was to determine time-dependent changes in diurnal blood pressure (BP) and urine production in acute spinal cord injury (SCI). SETTING: This study was conducted in a specialist, state-based spinal cord service in Victoria, Australia. METHODS: Consenting patients admitted consecutively with acute SCI were compared with patients confined to bed rest while awaiting surgery and with mobilising able-bodied controls...
June 28, 2016: Spinal Cord
Xing-Long Ye, Ling-Zhi Liu, Hai-Jun Jin
Many biological materials can readily modulate their mechanical properties and shape by interacting with water in the surrounding environment, which is essential to their high performance in application. In contrast, typical inorganic materials (such as the metals) cannot change their strength and shape without involving thermal/mechanical treatments. By introducing nano-scale porous structure and exploiting a simple physical concept-the water-capillarity in nanopores, here we report that a 'dead' metal can be transformed into a 'smart' material with water-responsive properties...
August 12, 2016: Nanotechnology
Francesca Saladini, Attilio Di Marco, Paolo Palatini
Cardiovascular autonomic dysfunction (AD) is a particular condition that can be detected by means of ambulatory blood pressure monitoring (ABPM). ABPM is helpful to identify some specific characteristics of haemodynamic AD, including non-dipping/reverse-dipping pattern, orthostatic and post-prandial hypotension and elevated blood pressure variability. These characteristics may be misdiagnosed with traditional, clinic blood pressure measurements. AD is relatively common in the real world. By analysing about 1000 recordings in a Cardiology unit, AD was found in 6...
September 2016: High Blood Pressure & Cardiovascular Prevention: the Official Journal of the Italian Society of Hypertension
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