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https://www.readbyqxmd.com/read/27926690/changes-of-blood-pressure-patterns-and-target-organ-damage-in-patients-with-chronic-kidney-disease-results-of-the-aprodite-2-study
#1
Ran-Hui Cha, Hajeong Lee, Jung Pyo Lee, Eunjeong Kang, Young Rim Song, Yon Su Kim, Sung Gyun Kim
OBJECTIVE: Blood pressure (BP) control is the most established practice for preventing the progression of chronic kidney disease (CKD). We examined the BP control and nocturnal dipping pattern changes in hypertensive patients with CKD and their effects on target organ damages. METHODS: We recruited 378 hypertensive CKD patients from four centers in Korea. The patients underwent clinic and ambulatory BP monitoring at the time of enrollment and 1 year later. RESULTS: The BP control states at the two time points were as follows: true controlled (16...
December 6, 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27916260/arsenic-solid-phase-speciation-and-reversible-binding-in-long-term-contaminated-soils
#2
M S Rahman, M W Clark, L H Yee, M J Comarmond, T E Payne, P Kappen, L Mokhber-Shahin
Historic arsenic contamination of soils occurs throughout the world from mining, industrial and agricultural activities. In Australia, the control of cattle ticks using arsenicals from the late 19th to mid 20th century has led to some 1600 contaminated sites in northern New South Wales. The effect of aging in As-mobility in two dip-site soil types, ferralitic and sandy soils, are investigated utilizing isotopic exchange techniques, and synchrotron X-ray adsorption spectroscopy (XAS). Findings show that historic soil arsenic is highly bound to the soils with >90% irreversibly bound...
December 1, 2016: Chemosphere
https://www.readbyqxmd.com/read/27901645/fenestrated-adipofascial-reverse-flap-a-modified-technique-for-the-reconstruction-of-fingertip-amputations
#3
Francesco Idone, Andrea Sisti, Juri Tassinari, Giuseppe Nisi
AIMS OF THE STUDY: Fingertip injuries can be treated in different ways, including shortening with primary closure, skin graft, and local or distant flaps. Several local flaps for the reconstruction of the amputated fingertip were described. We present our experience with a new concept of homodigital adipofascial reverse flap that avoids the second surgical stage and allows a complete and anatomically perfect reconstruction of nail bed, with preservation of the nail lamina. MATERIALS AND METHODS: Between March 2014 and February 2015, five patients with digital amputations (distally to the nail matrix) were treated using the Fenestrated Adipofascial Reverse (F...
November 30, 2016: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/27875953/management-of-hypertension-in-patients-with-chronic-kidney-disease-in-asia
#4
Qi-Fang Huang, Satoshi Hoshide, Hao-Min Cheng, Sungha Park, Chang-Gyu Park, Chen-Huan Chen, Kazuomi Kario, Ji-Guang Wang
Hypertension is both a cause and consequence of chronic kidney disease (CKD). According to the Chinese national survey in 2007-2010, the prevalence of CKD was much higher in hypertensive patients (18.9%, n=16,691) than in the overall population sample (10.8%, n=47,204). CKD in hypertension confers risks to the kidneys as well as other organs. Probably because of high dietary salt intake, Asian hypertensive patients with CKD show high prevalence of non-dipping and reversed dipping blood pressure pattern, and may have even higher risks of cardiovascular disease...
November 22, 2016: Current Hypertension Reviews
https://www.readbyqxmd.com/read/27855748/ambulatory-blood-pressure-monitoring-in-chinese-obstructive-sleep-apnea-patients
#5
Yan Ma, Shuchen Sun, Chung-Kang Peng, Yeming Fang, Robert J Thomas
STUDY OBJECTIVES: Nocturnal blood pressure (BP) dipping in patients with obstructive sleep apnea (OSA) has not yet been well investigated in Chinese patients, in whom the relationship of OSA and body mass index (BMI) is weaker than that in Caucasians. The aim of this study was to evaluate the BP profile, and the relationships between nocturnal BP and the severity of OSA, in Chinese patients. METHODS: Consecutive Chinese adult outpatients with suspected OSA had overnight polysomnography (PSG), office BP, and 24-h ambulatory BP monitoring (ABPM)...
November 14, 2016: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/27853909/not-all-drug-induced-parkinsonism-are-the-same-the-effect-of-drug-class-on-motor-phenotype
#6
Renato P Munhoz, Delcio Bertucci Filho, Hélio A G Teive
Drug-induced parkinsonism (DIP) is classically described as acute/subacute, bilateral symmetric syndrome in which tremor is infrequent compared to Parkinson's disease. Most DIP cases are caused by classic (CN) and second-generation neuroleptics (SN), and calcium channel blockers (CCB). We evaluated potentially distinctive demographic and clinical features in DIP among different drug classes. This was a prospective study of reversible DIP related to single selected drugs on each class. Baseline assessment included demographic, clinical data, and scales for staging, severity of motor signs of parkinsonism, tremor, and other involuntary movements...
November 16, 2016: Neurological Sciences
https://www.readbyqxmd.com/read/27778005/a-scanning-tunneling-microscopy-study-of-the-electronic-and-spin-states-of-bis-phthalocyaninato-terbium-iii-tbpc2-molecules-on-ag-111
#7
Ferdous Ara, Zhi Kun Qi, Jie Hou, Tadahiro Komeda, Keiichi Katoh, Masahiro Yamashita
In this article, we investigate a single molecule magnet bis(phthalocyaninato)terbium(iii) (TbPc2) molecule film by using low temperature STM. In order to investigate the effect of molecule-substrate interaction on the electronic and spin properties of the adsorbed molecule, we tune the molecule-substrate coupling by switching the substrate between Au(111) and Ag(111), the latter of which provides stronger interaction with the molecule than the former. Despite the enhanced chemical reactivity of the Ag(111) surface compared with Au(111), a well-organized pseudo-square film is formed...
October 25, 2016: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/27754083/os-19-06-change-of-blood-pressure-pattern-and-target-organ-damage-in-patients-with-chronic-kidney-disease-results-of-the-aprodite-2-study
#8
Ran-Hui Cha, Hajeong Lee, Jung Pyo Lee, Chun Soo Lim, Yon Su Kim, Sung Gyun Kim
OBJECTIVE: Blood pressure (BP) control is the most established practice for preventing the progression of chronic kidney disease (CKD). We examined the BP control and nocturnal dipping pattern change in hypertensive patients with CKD and its effects on target organ damages. DESIGN AND METHOD: We recruited 378 hypertensive CKD patients from 4 centers in Korea. They underwent office and ambulatory BP monitoring at the time of enrollment and 1 year after. High office and ambulatory BP was defined as > 140/90 mmHg and > 135/85 mmHg (daytime)/> 120/70 mmHg (nighttime), respectively...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27713498/prognostic-value-of-reverse-dipper-blood-pressure-pattern-in-chronic-kidney-disease-patients-not-undergoing-dialysis-prospective-cohort-study
#9
Cheng Wang, Zengchun Ye, Yan Li, Jun Zhang, Qunzi Zhang, Xinxin Ma, Hui Peng, Tanqi Lou
The "reverse dipping" blood pressure (BP) pattern has been studied among the general population and in individuals suffering from hypertension. However, the prognosis of this pattern in chronic kidney disease (CKD) patients is not known. We monitored BP throughout the day and followed health outcomes in 588 CKD patients admitted to our hospital. Time to all-cause mortality, cardiovascular mortality, renal events and cardiovascular events was recorded. Multivariate-adjusted Cox regression analyses were carried out to detect the prognostic value of a reverse dipping BP pattern...
October 7, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27661922/thermo-optic-effects-in-on-chip-lithium-niobate-microdisk-resonators
#10
Jie Wang, Bowen Zhu, Zhenzhong Hao, Fang Bo, Xiaolei Wang, Feng Gao, Yigang Li, Guoquan Zhang, Jingjun Xu
We report the experimental observation and theoretical analysis of thermo-optic effects in high-Q on-chip lithium-niobate (LN) microdisks. We find that the resonance transmission dip of a LN microdisk was broadened or compressed when the wavelength of the input laser was tuned to the shorter or the longer wavelengths at a wavelength sweeping speed of 4.8 pm/s. When the laser wavelength was shifted with a fast rate (4.8 nm/s), the tendencies of the change in the shape of the transmission dip reverse completely...
September 19, 2016: Optics Express
https://www.readbyqxmd.com/read/27643008/os-19-06-change-of-blood-pressure-pattern-and-target-organ-damage-in-patients-with-chronic-kidney-disease-results-of-the-aprodite-2-study
#11
Ran-Hui Cha, Hajeong Lee, Jung Pyo Lee, Chun Soo Lim, Yon Su Kim, Sung Gyun Kim
OBJECTIVE: Blood pressure (BP) control is the most established practice for preventing the progression of chronic kidney disease (CKD). We examined the BP control and nocturnal dipping pattern change in hypertensive patients with CKD and its effects on target organ damages. DESIGN AND METHOD: We recruited 378 hypertensive CKD patients from 4 centers in Korea. They underwent office and ambulatory BP monitoring at the time of enrollment and 1 year after. High office and ambulatory BP was defined as > 140/90 mmHg and > 135/85 mmHg (daytime)/> 120/70 mmHg (nighttime), respectively...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27620983/changes-in-fmri-bold-dynamics-reflect-anticipation-to-moving-objects
#12
W Schellekens, N F Ramsey, R J A van Wezel, M Raemaekers
The human brain is thought to respond differently to novel versus predictable neural input. In human visual cortex, neural response amplitude to visual input might be determined by the degree of predictability. We investigated how fMRI BOLD responses in human early visual cortex reflect the anticipation of a single moving bar's trajectory. We found that BOLD signals decreased linearly from onset to offset of the stimulus trajectory. Moreover, decreased amplitudes of BOLD responses coincided with an increased initial dip as the stimulus moved along its trajectory...
September 9, 2016: NeuroImage
https://www.readbyqxmd.com/read/27615446/the-effect-of-nitrazepam-on-depression-and-curiosity-in-behavioral-tests-in-mice-the-role-of-potassium-channels
#13
Vahid Nikoui, Sattar Ostadhadi, Pardis Azhand, Samira Zolfaghari, Shayan Amiri, Mehrdad Foroohandeh, Manijeh Motevalian, Ali Mohammad Sharifi, Azam Bakhtiarian
Evidence show that gamma-aminobutyric acid (GABA) receptors are involved in depression, so the aim of this study was to investigate the effect of nitrazepam as agonist of GABAA receptors on depression and curiosity in male mice and the role of potassium channel in antidepressant-like response. For this purpose, we studied the antidepressant-like properties of fluoxetine, nitrazepam, glibenclamide, and cromakalim by both forced swimming test (FST) and tail suspension test (TST). Animals were injected by various doses of nitrazepam (0...
September 9, 2016: European Journal of Pharmacology
https://www.readbyqxmd.com/read/27615192/ambulatory-blood-pressure-monitoring-for-the-effective-management-of-antihypertensive-drug-treatment
#14
Eoin O'Brien, Eamon Dolan
PURPOSE: This purpose of this article is to review the current recommendations for ambulatory blood pressure measurement (ABPM) and the use of ABPM in assessing treatment. METHODS: We review current international guidelines and undertake a critical review of evidence supporting the clinical use of ABPM in effectively managing antihypertensive drug treatment. FINDINGS: Current guidelines emphasize the diagnostic superiority of ABPM, mainly from the ability of the technique to identify sustained hypertension by allowing for the exclusion of white-coat hypertension and by demonstrating the presence of masked hypertension...
September 8, 2016: Clinical Therapeutics
https://www.readbyqxmd.com/read/27612835/electrochemical-and-dft-study-of-an-anticancer-and-active-anthelmintic-drug-at-carbon-nanostructured-modified-electrode
#15
Masoumeh Ghalkhani, Javad Beheshtian, Maryam Salehi
The electrochemical response of mebendazole (Meb), an anticancer and effective anthelmintic drug, was investigated using two different carbon nanostructured modified glassy carbon electrodes (GCE). Although, compared to unmodified GCE, both prepared modified electrodes improved the voltammetric response of Meb, the carbon nanotubes (CNTs) modified GCE showed higher sensitivity and stability. Therefore, the CNTs-GCE was chosen as a promising candidate for the further studies. At first, the electrochemical behavior of Meb was studied by cyclic voltammetry and differential pulse and square wave voltammetry...
December 1, 2016: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/27608183/effect-of-restoring-sinus-rhythm-in-hypertensive-patients-with-atrial-fibrillation-undergoing-electrical-cardioversion
#16
Monica Maselli, Valter Giantin, Alessandro Franchin, Francesca Attanasio, Alessandra Tramontano, Pietro De Toni, Valentina Pengo, Domenico Corrado, Enzo Manzato
INTRODUCTION: Little is known about the effects of atrial fibrillation (AF) on blood pressure (BP) levels in hypertensive patients. Some studies suggest a role for rhythm control in managing such patients' BP, but the improvement observed in cardiac performance after restoring sinus rhythm (SR) may coincide with an increase in BP. The aim of this study was to apply ambulatory BP monitoring to analyze BP changes in hypertensive patients after electrical cardioversion for persistent AF...
September 7, 2016: Blood Pressure Monitoring
https://www.readbyqxmd.com/read/27591018/cross-sectional-study-on-the-relationship-between-the-level-of-serum-cystatin-c-and-blood-pressure-reverse-dipping-in-hypertensive-patients
#17
Jin Han, Ya Gao, Qi Guo, Dan Su, Bin Yan, Liyuan Peng, Yuxing Du, Ke Li, Gang Wang
OBJECTIVE: To investigate the relationship between the level of serum cystatin C (s-CC) and reverse-dipper blood pressure (BP) pattern. DESIGN: Cross-sectional study. SETTING: Single centre. PARTICIPANTS: A total of 718 hypertensive patients were eventually recruited from cardiac clinics between 2012 and 2014 in the Second Affiliated Hospital, Xi'an Jiaotong University. They were diagnosed as essential hypertension according to their casual office records of systolic blood pressure (SBP) and/or diastolic blood pressure (DBP)...
2016: BMJ Open
https://www.readbyqxmd.com/read/27551887/toward-high-performance-hematite-nanotube-photoanodes-charge-transfer-engineering-at-heterointerfaces
#18
Do Hong Kim, Dinsefa M Andoshe, Young-Seok Shim, Cheon-Woo Moon, Woonbae Sohn, Seokhoon Choi, Taemin Ludvic Kim, Migyoung Lee, Hoonkee Park, Kootak Hong, Ki Chang Kwon, Jun Min Suh, Jin-Sang Kim, Jong-Heun Lee, Ho Won Jang
Vertically ordered hematite nanotubes are considered to be promising photoactive materials for high-performance water-splitting photoanodes. However, the synthesis of hematite nanotubes directly on conducting substrates such as fluorine-doped tin oxide (FTO)/glass is difficult to be achieved because of the poor adhesion between hematite nanotubes and FTO/glass. Here, we report the synthesis of hematite nanotubes directly on FTO/glass substrate and high-performance photoelectrochemical properties of the nanotubes with NiFe cocatalysts...
September 14, 2016: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/27525859/analysis-of-persistent-changes-to-%C3%AE-aminobutyric-acid-receptor-gene-expression-in-plutella-xylostella-subjected-to-sublethal-amounts-of-spinosad
#19
X-H Yin, Q-J Wu, Y-J Zhang, Y-H Long, X-M Wu, R-Y Li, M Wang, X-L Tian, X-G Jiao
A multi-generational approach was used to investigate the persistent effects of a sub-lethal dose of spinosad in Plutella xylostella. The susceptibility of various sub-populations of P. xylostella to spinosad and the effects of the insecticide on the gene expression of γ-aminobutyric acid receptor (GABAR) were determined. The results of a leaf dip bioassay showed that the sensitivity of P. xylostella to spinosad decreased across generations. The sub-strains had been previously selected based on a determined LC25 of spinosad...
2016: Genetics and Molecular Research: GMR
https://www.readbyqxmd.com/read/27508622/-op-1a-04-24h-ambulatory-blood-pressure-monitoring-profile-in-parkinson-s-disease-with-autonomic-neuropathy
#20
V Milazzo, C Di Stefano, F Vallelonga, G Sobrero, A Milan, M Zibetti, M Sarchioto, A Romagnolo, L Lopiano, F Veglio, S Maule
OBJECTIVE: Patients with Autonomic Neuropathy (AN) are characterized by orthostatic hypotension (OH), supine hypertension, high blood pressure (BP) variability and reverse dipping pattern on 24 h Ambulatory Blood Pressure Monitoring (24 h ABPM). AN is a common finding in Parkinson's disease (PD), and it is related to a higher motor impairment due to neurogenic OH. Aim of the study was the evaluation of the prevalence of AN and the assessment of the related 24 h ABPM profile in PD patients without known cardiovascular comorbidities...
September 2016: Journal of Hypertension
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