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https://www.readbyqxmd.com/read/28736895/independent-association-between-age-and-circadian-systolic-blood-pressure-patterns-in-adults-with-hypertension
#1
Ming Deng, Da-Wei Chen, Yi-Fei Dong, Peng Lu, Bi-Ming Zhan, Jian-Qing Xu, Xi-Xin Ji, Ping Li, Xiao-Shu Cheng
Previous studies indicate a preliminary association between age and circadian blood pressure (BP) variation. This association would be affected by confounding factors in real-world populations. The authors investigated whether this is a convincingly independent association in a real-world population of adults with hypertension. Clinical data and findings of 24-hour ambulatory BP monitoring were obtained from 297 consecutive adults with hypertension (60.19±0.77 years). BP dipping patterns were categorized based on the percentage of nocturnal BP drop...
July 23, 2017: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/28733831/nocturnal-blood-pressure-dipping-is-abolished-in-old-elderly-hospitalized-patients
#2
Francesco Salvo, Chiara Lonati, Michele Berardi, Andrea Riccardo Errani, Carlo Lorenzo Muzzulini, Alberto Morganti
INTRODUCTION: During sleep there is reduction of blood pressure (BP) caused by a decrease of the sympathetic nervous tone. This nocturnal "dipping" phenomenon, assessable with ambulatory blood pressure monitoring (ABPM), is blunted with increasing age. AIM: To assess the effect of hospitalization on night-time BP fall in old-elderly patients. METHODS: We analysed 78 ABPM of old-elderly hospitalized patients (mean age 91 ± 0.5 years) and those of 18 outpatients as control group...
July 22, 2017: High Blood Pressure & Cardiovascular Prevention: the Official Journal of the Italian Society of Hypertension
https://www.readbyqxmd.com/read/28704507/regular-moist-snuff-dipping-does-not-affect-endurance-exercise-performance
#3
Frida Björkman, Fredrik Edin, C Mikael Mattsson, Filip Larsen, Björn Ekblom
Physiological and medical effects of snuff have previously been obtained either in cross-sectional studies or after snuff administration to non-tobacco users. The effects of snuff cessation after several years of daily use are unknown. 24 participants with >2 years of daily snuff-use were tested before and after >6 weeks snuff cessation (SCG). A control group (CO) of 11 snuff users kept their normal habits. Resting heart rate (HR) and blood pressure (BP) were significantly lower in SCG after snuff cessation, and body mass was increased by 1...
2017: PloS One
https://www.readbyqxmd.com/read/28701886/overexpression-of-ginseng-ugt72al1-causes-organ-fusion-in-the-axillary-leaf-branch-of-arabidopsis
#4
Ngoc Quy Nguyen, Ok Ran Lee
BACKGROUND: Glycosylation of natural compounds increases the diversity of secondary metabolites. Glycosylation steps are implicated not only in plant growth and development, but also in plant defense responses. Although the activities of uridine-dependent glycosyltransferases (UGTs) have long been recognized, and genes encoding them in several higher plants have been identified, the specific functions of UGTs in planta remain largely unknown. METHODS: Spatial and temporal patterns of gene expression were analyzed by quantitative reverse transcription (qRT)-polymerase chain reaction (PCR) and GUS histochemical assay...
July 2017: Journal of Ginseng Research
https://www.readbyqxmd.com/read/28701884/cis-prenyltransferase-interacts-with-a-nogo-b-receptor-homolog-for-dolichol-biosynthesis-in-panax-ginseng-meyer
#5
Ngoc Quy Nguyen, Sang-Choon Lee, Tae-Jin Yang, Ok Ran Lee
BACKGROUND: Prenyltransferases catalyze the sequential addition of isopentenyl diphosphate units to allylic prenyl diphosphate acceptors and are classified as either trans-prenyltransferases (TPTs) or cis-prenyltransferases (CPTs). The functions of CPTs have been well characterized in bacteria, yeast, and mammals compared to plants. The characterization of CPTs also has been less studied than TPTs. In the present study, molecular cloning and functional characterization of a CPT from a medicinal plant, Panax ginseng Mayer were addressed...
July 2017: Journal of Ginseng Research
https://www.readbyqxmd.com/read/28692165/clinical-and-prognostic-significance-of-a-reverse-dipping-pattern-on-ambulatory-monitoring-an-updated-review
#6
REVIEW
Cesare Cuspidi, Carla Sala, Marijana Tadic, Elisa Gherbesi, Antonio De Giorgi, Guido Grassi, Giuseppe Mancia
Reverse or inverted dipping (ie, the phenomenon characterized by higher nighttime compared with daytime blood pressure values) is an alteration of circadian blood pressure rhythm frequently documented in hypertension, type 2 diabetes mellitus, chronic kidney disease, and sleep apnea syndrome, and generally regarded as a harmful condition. Available literature on the clinical and prognostic implications of reverse dipping is scanty. The present article will review a number of relevant issues concerning reverse dipping, in particular: (1) its possible mechanisms; (2) prevalence and clinical correlates, (3) concomitant cardiac and extracardiac subclinical organ damage; (4) association with acute and chronic cardiovascular diseases; (5) prognostic value in predicting cardiovascular events and mortality; and (6) therapeutic interventions aimed at reverting this abnormal circadian blood pressure rhythm...
July 2017: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/28668444/the-effect-of-circadian-blood-pressure-pattern-on-presence-of-fragmented-qrs-complexes-in-hypertensive-subjects
#7
Mehmet Eyuboglu, Yavuz Karabag, Suleyman Karakoyun, Bahri Akdeniz
The association of deteriorated circadian blood pressure (BP) variability with presence of fragmented QRS (fQRS) on electrocardiography (ECG) is not clear. The present study aims to evaluate the relationship of BP patterns with presence of fQRS on ECG. A total of 338 consecutive newly diagnosed and never treated hypertensive patients who are without left ventricular hypertrophy and underwent 24-hour ambulatory BP monitoring were enrolled. Patients were classified as dippers, nondippers, and reverse dippers according to ambulatory BP monitoring results...
June 12, 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/28637401/relationship-between-ambulatory-arterial-stiffness-index-aasi-and-night-day-blood-pressure-ratio-in-essential-hypertensives
#8
Domenico Di Raimondo, Alessandra Casuccio, Rosangela Di Liberti, Gaia Musiari, Valentina Zappulla, Alessandra D'angelo, Antonio Pinto
BACKGROUND: Ambulatory Arterial Stiffness Index (AASI) has been proposed as an indirect and simpler method to estimate the Arterial Stiffness (AS). AASI, calculated from a set of data collected during a 24-hours ambulatory blood pressure monitoring (ABPM), is defined as 1 minus the regression slope of diastolic on systolic blood pressure (BP) values. For a given increase in diastolic BP, the increase in systolic BP is smaller in a compliant compared to a stiff artery; the stiffer the arterial tree, the closer AASI is to 1...
June 21, 2017: Current Hypertension Reviews
https://www.readbyqxmd.com/read/28591980/dip-coating-process-engineering-and-performance-optimization-for-three-state-electrochromic-devices
#9
Lu Wu, Dejiang Yang, Lixun Fei, Yue Huang, Fang Wu, Yiling Sun, Jiayuan Shi, Yong Xiang
Titanium dioxide (TiO2) nanoparticles were modified onto fluorine-doped tin oxide (FTO) via dip-coating technique with different nanoparticle sizes, lifting speeds, precursor concentrations, and dipping numbers. Electrodeposition-based electrochromic device with reversible three-state optical transformation (transparent, mirror, and black) was fabricated subsequently by sandwiching a suitable amount of gel electrolyte between modified FTO electrode and flat FTO electrode. Correlation between dip-coating process engineering, morphological features of TiO2 thin films, i...
December 2017: Nanoscale Research Letters
https://www.readbyqxmd.com/read/28582627/gyrification-inspired-highly-convoluted-graphene-oxide-patterns-for-ultralarge-deforming-actuators
#10
Yinlong Tan, Zengyong Chu, Zhenhua Jiang, Tianjiao Hu, Gongyi Li, Jia Song
Gyrification in the human brain is driven by the compressive stress induced by the tangential expansion of the cortical layer, while similar topographies can also be induced by the tangential shrinkage of the spherical substrate. Herein we introduce a simple three-dimensional (3D) shrinking method to generate the cortex-like patterns using two-dimensional (2D) graphene oxide (GO) as the building blocks. By rotation-dip-coating a GO film on an air-charged latex balloon and then releasing the air slowly, a highly folded hydrophobic GO surface can be induced...
June 9, 2017: ACS Nano
https://www.readbyqxmd.com/read/28544243/evening-versus-morning-dosing-regimen-drug-therapy-for-chronic-kidney-disease-patients-with-hypertension-in-blood-pressure-patterns-a-systematic-review-and-meta-analysis
#11
Caixia Wang, Yuqiu Ye, Chunyong Liu, Yongming Zhou, Linsheng Lv, Cailian Cheng, Shaomin Li, Tanqi Lou, Xun Liu
BACKGROUND: Evening dosing regimen drug therapy on blood pressure (BP) control is used widely, but its clinical benefits and preservation or re-establishment of normal 24-hour BP dipping pattern in chronic kidney disease (CKD) patients is not known. AIMS: To investigate the effect of evening dosing regimen of antihypertensive drugs on blood pressure patterns to CKD patients with hypertension. METHODS: We did a systematic review by searching PUBMED, EMBASE, ASN-ONLINE, the Cochrane Library and the reference lists of relevant articles of published papers...
May 24, 2017: Internal Medicine Journal
https://www.readbyqxmd.com/read/28471650/food-quality-monitor-paper-based-plasmonic-sensors-prepared-through-reversal-nanoimprinting-for-rapid-detection-of-biogenic-amine-odorants
#12
Shih-Yu Tseng, Szu-Ying Li, Shang-Yi Yi, Aileen Y Sun, Dong-Yu Gao, Dehui Wan
This paper describes the fabrication of paper-based plasmonic refractometric sensors through the embedding of metal nanoparticles (NPs) onto flexible papers using reversal nanoimprint lithography. The NP-embedded papers can serve as gas sensors for the detection of volatile biogenic amines (BAs) released from spoiled food. Commercial inkjet papers were employed as sensor substrates-their high reflectance (>80%) and smooth surfaces (roughness: ca. 4.9 nm) providing significant optical signals for reflection-mode plasmonic refractometric sensing and high particle transfer efficiency, respectively; in addition, because inkjet papers have lightweight and are burnable and flexible, they are especially suitable for developing portable, disposable, cost-effective, eco-friendly sensing platforms...
May 11, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28451152/gradient-doping-of-phosphorus-in-fe2o3-nanoarray-photoanodes-for-enhanced-charge-separation
#13
Zhibin Luo, Chengcheng Li, Shanshan Liu, Tuo Wang, Jinlong Gong
Hematite (α-Fe2O3) is a promising candidate for solar-to-hydrogen energy conversion. However, the low carrier mobility and extremely high charge recombination rate limit the practical application of hematite in solar water splitting. This paper describes the fabrication of a Fe2O3 photoanode with gradient incorporation of phosphorus (P) employing a facile dipping and annealing method to improve the charge separation for enhanced photoelectrochemical water oxidation. This gradient P incorporation increases the width of band bending over a large region in Fe2O3, which is crucial for promoting the charge separation efficiency in the bulk...
January 1, 2017: Chemical Science
https://www.readbyqxmd.com/read/28407712/relationship-between-young-s-modulus-and-film-architecture-in-cellulose-nanofibril-based-multilayered-thin-films
#14
Firas Azzam, Laurent Chaunier, Céline Moreau, Denis Lourdin, Patricia Bertoncini, Bernard Cathala
Young's moduli of cellulose nanofibril (CNF)-poly(allylamine hydrochloride) (PAH) multilayered thin films were measured using strain-induced elastic buckling instability for mechanical measurements (SIEBIMM) and the quantitative nanomechanical mapping technique (PF-QNM). To establish the relationship between structure and mechanical properties, three types of films with various architectures were built using the layer-by-layer method by changing the ionic strength of the dipping solution. Both methods demonstrate that the architecture of a film has a strong impact on its mechanical properties even though the film has similar cellulose content, emphasizing the role of the architecture...
April 20, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28381465/associations-of-blood-pressure-dipping-patterns-with-left-ventricular-mass-and-left-ventricular-hypertrophy-in-blacks-the-jackson-heart-study
#15
Marwah Abdalla, Melissa C Caughey, Rikki M Tanner, John N Booth, Keith M Diaz, D Edmund Anstey, Mario Sims, Joseph Ravenell, Paul Muntner, Anthony J Viera, Daichi Shimbo
BACKGROUND: Abnormal diurnal blood pressure (BP), including nondipping patterns, assessed using ambulatory BP monitoring, have been associated with increased cardiovascular risk among white and Asian adults. We examined the associations of BP dipping patterns (dipping, nondipping, and reverse dipping) with cardiovascular target organ damage (left ventricular mass index and left ventricular hypertrophy), among participants from the Jackson Heart Study, an exclusively black population-based cohort...
April 5, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28320765/effect-of-uric-acid-lowering-on-renin-angiotensin-system-activation-and-ambulatory-bp-a-randomized-controlled-trial
#16
Ciaran J McMullan, Lea Borgi, Naomi Fisher, Gary Curhan, John Forman
BACKGROUND AND OBJECTIVES: Higher serum uric acid levels, even within the reference range, are strongly associated with increased activity of the renin-angiotensin system (RAS) and risk of incident hypertension. However, the effect of lowering serum uric acid on RAS activity in humans is unknown, although the data that lowering serum uric acid can reduce BP are conflicting. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: In a double-blind placebo-controlled trial conducted from 2011 to 2015, we randomly assigned 149 overweight or obese adults with serum uric acid ≥5...
May 8, 2017: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/28266630/cluster-analysis-a-new-approach-for-identification-of-underlying-risk-factors-for-coronary-artery-disease-in-essential-hypertensive-patients
#17
Qi Guo, Xiaoni Lu, Ya Gao, Jingjing Zhang, Bin Yan, Dan Su, Anqi Song, Xi Zhao, Gang Wang
Grading of essential hypertension according to blood pressure (BP) level may not adequately reflect clinical heterogeneity of hypertensive patients. This study was carried out to explore clinical phenotypes in essential hypertensive patients using cluster analysis. This study recruited 513 hypertensive patients and evaluated BP variations with ambulatory blood pressure monitoring. Four distinct hypertension groups were identified using cluster analysis: (1) younger male smokers with relatively high BP had the most severe carotid plaque thickness but no coronary artery disease (CAD); (2) older women with relatively low diastolic BP had more diabetes; (3) non-smokers with a low systolic BP level had neither diabetes nor CAD; (4) hypertensive patients with BP reverse dipping were most likely to have CAD but had least severe carotid plaque thickness...
March 7, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28236344/integration-of-high-risk-human-papillomavirus-into-cellular-cancer-related-genes-in-head-and-neck-cancer-cell-lines
#18
Heather M Walline, Christine M Goudsmit, Jonathan B McHugh, Alice L Tang, John H Owen, Bin T Teh, Erin McKean, Thomas W Glover, Martin P Graham, Mark E Prince, Douglas B Chepeha, Steven B Chinn, Robert L Ferris, Susanne M Gollin, Thomas K Hoffmann, Henning Bier, Ruud Brakenhoff, Carol R Bradford, Thomas E Carey
BACKGROUND: Human papillomavirus (HPV)-positive oropharyngeal cancer is generally associated with excellent response to therapy, but some HPV-positive tumors progress despite aggressive therapy. The purpose of this study was to evaluate viral oncogene expression and viral integration sites in HPV16- and HPV18-positive squamous cell carcinoma lines. METHODS: E6/E7 alternate transcripts were assessed by reverse transcriptase-polymerase chain reaction (RT-PCR). Detection of integrated papillomavirus sequences (DIPS-PCR) and sequencing identified viral insertion sites and affected host genes...
May 2017: Head & Neck
https://www.readbyqxmd.com/read/28231683/the-adverse-effects-of-exercise-and-supraphysiological-dose-of-testosterone-enanthate-te-on-exploratory-activity-in-elevated-plus-maze-epm-test-indications-for-using-total-exploratory-activity-tea-as-a-new-parameter-for-ex
#19
Dragica Selakovic, Jovana Joksimovic, Dragan Obradovic, Dragan Milovanovic, Milos Djuric, Gvozden Rosic
OBJECTIVES: The aim of this study was the estimation of effects induced by chronic administration of supraphysiological dose of TE and prolonged exercise in male rats on anxiety levels (alterations in exploratory activity patterns in EPM). MATERIAL AND METHODS: Two sedentary (control - C and testosterone-enanthate - T) and two exercise (exercise - E and testosterone-enanthate plus exercise - T+E) groups (n=32) underwent adequate protocols - the swimming protocol (1 h/day) and TE (20 mg/kg/w, s...
October 2016: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/28183366/effects-of-almond-consumption-on-the-post-lunch-dip-and-long-term-cognitive-function-in-energy-restricted-overweight-and-obese-adults
#20
RANDOMIZED CONTROLLED TRIAL
Jaapna Dhillon, Sze-Yen Tan, Richard D Mattes
The post-lunch dip in cognition is a well-established phenomenon of decreased alertness, memory and vigilance after lunch consumption. Lunch composition reportedly influences the post-lunch dip. Moreover, dieting is associated with cognitive function impairments. The negative effects of dieting have been reversed with nut-supplemented diets. The aims of this study were to (1) evaluate the acute effect of an almond-enriched high-fat lunch or high-carbohydrate lunch on the post-lunch decline in cognitive function, and (2) evaluate the effects of chronic almond consumption as part of an energy-restricted diet on the memory and attention domains of cognitive function...
February 2017: British Journal of Nutrition
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