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https://www.readbyqxmd.com/read/29436105/the-association-of-nocturnal-hypertension-and-nondipping-blood-pressure-with-treatment-resistant-hypertension-the-jackson-heart-study
#1
Marguerite R Irvin, John N Booth, Mario Sims, Adam P Bress, Marwah Abdalla, Daichi Shimbo, David A Calhoun, Paul Muntner
Apparent treatment-resistant hypertension (aTRH), nocturnal hypertension, and nondipping blood pressure (BP) have shared risk factors. The authors studied the association between aTRH and nocturnal hypertension and aTRH and nondipping BP among 524 black Jackson Heart Study participants treated for hypertension. Nocturnal hypertension was defined by mean nighttime systolic BP ≥120 mm Hg or diastolic BP ≥70 mm Hg. Nondipping BP was defined by mean nighttime to daytime systolic BP ratio >0.90. aTRH was defined by mean clinic systolic BP ≥140 mm Hg and/or diastolic BP ≥90 mm Hg with three medication classes or treatment with four or more classes...
February 13, 2018: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/29420078/poor-sleep-is-responsible-for-the-impaired-nocturnal-blood-pressure-dipping-in-elderly-hypertensive-a-cross-sectional-study-of-elderly
#2
Shaopan Zhao, Shihui Fu, Jiefeng Ren, Leiming Luo
OBJECTIVE: This study was aimed to assess whether sleep disorder was associated with an increased risk of less nocturnal blood pressure (BP) dipping in elderly patients with hypertension. METHODS: Cases were 1006 patients, aged >60 years, who were admitted to hospital with diagnosed hypertension during 2016-2017, and were divided into three groups with the systolic nocturnal BP dipping of 10%, and 0% as the cut-off value. The patients' sleep was evaluated by Pittsburgh sleep quality index (PSQI)...
February 8, 2018: Clinical and Experimental Hypertension: CHE
https://www.readbyqxmd.com/read/29404785/implementing-abpm-into-clinical-practice
#3
Alan L Hinderliter, Raven A Voora, Anthony J Viera
PURPOSE OF REVIEW: To review the data supporting the use of ambulatory blood pressure monitoring (ABPM), and to provide practical guidance for practitioners who are establishing an ambulatory monitoring service. RECENT FINDINGS: ABPM results more accurately reflect the risk of cardiovascular events than do office measurements of blood pressure. Moreover, many patients with high blood pressure in the office have normal blood pressure on ABPM-a pattern known as white coat hypertension-and have a prognosis similar to individuals who are normotensive in both settings...
February 5, 2018: Current Hypertension Reports
https://www.readbyqxmd.com/read/29402981/clinical-features-and-therapeutic-perspectives-on-hypertension-in-diabetics
#4
REVIEW
Shigehiro Katayama, Masako Hatano, Masashi Issiki
Over 50% of patients with diabetes mellitus, either type 1 or 2, ultimately develop hypertension as a complication. In diabetics, this further increases the incidence of cardiovascular disease (CVD) by 2- to 3-fold and accelerates the progression of diabetic nephropathy. Arteriosclerosis, a clinical feature of hypertension in diabetics, develops and advances from a young age. Therefore, in providing treatment, it is necessary to evaluate the degree of arteriosclerosis. Diabetic patients are encouraged to strictly control their blood glucose levels...
February 5, 2018: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/29390325/evaluation-of-tolerance-to-ambulatory-blood-pressure-monitoring-analysis-of-dipping-profile-in-a-large-cohort-of-hypertensive-patients
#5
Gino Iannucci, Luigi Petramala, Giuseppe La Torre, Barbara Barbaro, Clara Balsano, Pietro Giacomo Curatulo, Francesco Amadei, Marino Paroli, Antonio Concistrè, Claudio Letizia
Ambulatory blood pressure monitoring (ABPM) is a helpful tool to comprehensively identify and diagnose arterial hypertension. Moreover, it allows to better identify alterations in the circadian BP profile, as the nocturnal "nondipping" status, characterized by a lack of the physiological 10% night BP reduction and associated with a greater risk of target organ damage. However, ABPM has some limitations such as restricted availability, discomfort, particularly at night, cost implications, and reproducibility...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29385702/altered-circadian-timing-system-mediated-non-dipping-pattern-of-blood-pressure-and-associated-cardiovascular-disorders-in-metabolic-and-kidney-diseases
#6
REVIEW
Asadur Rahman, Arif Ul Hasan, Akira Nishiyama, Hiroyuki Kobori
The morning surge in blood pressure (BP) coincides with increased cardiovascular (CV) events. This strongly suggests that an altered circadian rhythm of BP plays a crucial role in the development of CV disease (CVD). A disrupted circadian rhythm of BP, such as the non-dipping type of hypertension (i.e., absence of nocturnal BP decline), is frequently observed in metabolic disorders and chronic kidney disease (CKD). The circadian timing system, controlled by the central clock in the suprachiasmatic nucleus of the hypothalamus and/or by peripheral clocks in the heart, vasculature, and kidneys, modulates the 24 h oscillation of BP...
January 30, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29374807/the-sacubitril-valsartan-a-first-in-class-angiotensin-receptor-neprilysin-inhibitor-arni-potential-uses-in-hypertension-heart-failure-and-beyond
#7
REVIEW
Kazuomi Kario
PURPOSE OF REVIEW: Sacubitril/valsartan (LCZ696) is a first-in-class, novel-acting, angiotensin receptor neprilysin inhibitor (ARNI) that provides inhibition of neprilysin and the angiotensin (AT1) receptor. A recent clinical trial PRARDIGM-HF demonstrated that this drug is superior to angiotensin-converting enzyme (ACE) inhibitors for improving the prognosis in the patients with heart failure, and this has resulted in the drug being included in clinical practice guidelines for the management of heart failure with reduced ejection fraction (EF)...
January 27, 2018: Current Cardiology Reports
https://www.readbyqxmd.com/read/29363362/sleep-disordered-breathing-in-pregnant-women-maternal-and-fetal-risk-treatment-considerations-and-future-perspectives
#8
Kimberly Truong, Christian Guilleminault
Numerous physiologic and anatomic changes during pregnancy exacerbate or unmask obstructive sleep apnea in women. Left untreated, upper airway flow limitation during pregnancy may lead to dire maternal and fetal health consequences. Areas covered: This review outlines the relationship between sleep disordered breathing (SDB) and gestational hypertension, preeclampsia, and gestational diabetes. It also discusses the implications of SDB on fetal and maternal health and concludes with a review of the emerging literature of treatment options for SDB in pregnancy and its benefit...
January 24, 2018: Expert Review of Respiratory Medicine
https://www.readbyqxmd.com/read/29354177/the-influence-of-adding-tomato-extract-and-acetylsalicylic-acid-to-hypotensive-therapy-on-the-daily-blood-pressure-profiles-of-patients-with-arterial-hypertension-and-high-cardiovascular-risk
#9
Angelika N Osińska, Beata Begier-Krasińska, Piotr Rzymski, Aleksandra Krasińska, Andrzej Tykarski, Zbigniew Krasiński
Introduction: Arterial hypertension (HT) is one of the most common diseases around the world and constitutes a significant medical, social, and economic problem. Lifestyle changes, including adequate fruit and vegetable consumption, play an important role in controlling blood pressure (BP) and other cardiovascular risk factors. Aim: To compare the influence of adding acetylsalicylic acid (ASA) or standardized tomato extract (STE) to standard hypotensive therapy on the values of arterial pressure and the daily blood pressure profiles of patients with hypertension and high cardiovascular risk...
December 2017: Kardiochirurgia i Torakochirurgia Polska, Polish Journal of Cardio-Thoracic Surgery
https://www.readbyqxmd.com/read/29338120/the-association-between-different-features-of-sleep-disordered-breathing-and-blood-pressure-a-cross-sectional-study
#10
Shayan Khoshkish, Mathias Hohl, Benedikt Linz, Michael Arzt, Felix Mahfoud, Mathias Baumert, Jakob Schöpe, Michael Böhm, Dominik Linz
Sleep disordered breathing (SDB) is highly prevalent in patients with high blood pressure (BP). Severity of SDB can be evaluated by the number of apneas and hypopneas per hour (AHI) or by measures of hypoxia. The objective of this study was to assess the association between different measures of SDB and BP. In 134 consecutive patients, polygraphy was performed to determine the AHI. Pulse oximetry was used to determine hypoxemic burden (time below 90% oxygen saturation [T90] and hypoxia load [HL], representing the integrated area above the curve of desaturation)...
January 16, 2018: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/29321408/the-factors-affecting-the-non-dipper-pattern-in-japanese-patients-with-severe-obstructive-sleep-apnea
#11
Hiromitsu Sekizuka, Naohiko Osada, Yoshihiro J Akashi
Objective Obstructive sleep apnea (OSA) is assumed to influence the circadian blood pressure (BP) fluctuation, particularly causing nocturnal hypertension and changing the dipping pattern of nocturnal BP. This study aimed to clarify the triggers of the non-dipper pattern in nocturnal BP in Japanese patients with severe OSA (the apnea-hypopnea index ≥30/h). Methods Of 541 patients with OSA diagnosed using polysomnography (PSG) and ambulatory BP monitoring (ABPM), 163 patients <60 years of age (Younger group) and 101 patients ≥60 years of age (Older group) were stratified into the dipper or non-dipper pattern groups...
January 11, 2018: Internal Medicine
https://www.readbyqxmd.com/read/29318587/new-perspectives-on-the-role-of-melatonin-in-human-sleep-circadian-rhythms-and-their-regulation
#12
REVIEW
N Zisapel
In mammals a central circadian clock, located in the suprachiasmatic nuclei (SCN) of the hypothalamus, tunes the innate circadian physiological rhythms to the ambient 24h light-dark cycle to invigorate and optimize the internal temporal order. The SCN-activated, light- inhibited production of melatonin conveys the message of darkness to the clock and induces night state in physiological function, e.g., sleep/wake blood pressure and metabolism. Clinically meaningful effects of melatonin treatment have been demonstrated in placebo-controlled trials in humans, particularly in disorders associated with diminished or misaligned melatonin rhythms, e...
January 10, 2018: British Journal of Pharmacology
https://www.readbyqxmd.com/read/29316213/comparative-effects-of-valsartan-plus-either-cilnidipine-or-hydrochlorothiazide-on-home-morning-blood-pressure-surge-evaluated-by-information-and-communication-technology-based-nocturnal-home-blood-pressure-monitoring
#13
Takeshi Fujiwara, Naoko Tomitani, Hiroshi Kanegae, Kazuomi Kario
The authors tested the hypothesis that a valsartan/cilnidipine combination would suppress the home morning blood pressure (BP) surge (HMBPS) more effectively than a valsartan/hydrochlorothiazide combination in patients with morning hypertension, defined as systolic BP (SBP) ≥135 mm Hg or diastolic BP ≥85 mm Hg assessed by a self-measuring information and communication technology-based home BP monitoring device more than three times before either combination's administration. This was an 8-week prospective, multicenter, randomized, open-label clinical trial...
January 5, 2018: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/29313563/adropin-and-circadian-variation-of-blood-pressure
#14
Hasan Ata Bolayır, Tarık Kıvrak, Hakan Gunes, Aslı Bolayır, Ilgın Karaca
BACKGROUND: Nocturnal hypertension and non-dipping pattern are often associated with endothelial dysfunction. Previous studies suggested that adropin, a novel secreted energy homeostasis protein, has unique effects to regulate endothelial cell function. AIM: This study aims to investigate the association between absolute nighttime blood pressure (BP) and circadian BP pattern with serum adropin and high-sensitivity C-reactive protein (hsCRP) levels in patients with newly diagnosed untreated hypertension...
January 9, 2018: Kardiologia Polska
https://www.readbyqxmd.com/read/29303603/sleep-apnoea-in-patients-with-nocturnal-hypertension-a-multicentre-study-in-the-czech-republic
#15
M Hobzova, K Sonka, M Pretl, J Vaclavik, E Kriegova, M Radvansky, J Zapletalova, M Plackova, V Kolek
Sleep apnoea (SA) is common in patients with hypertension. Nowadays, limited data on the prevalence of SA in nocturnal hypertension (NH) exist. We, therefore, studied the occurrence of SA in Czech patients and its association with 24-hour ambulatory blood pressure monitoring (ABPM), breathing disturbances in sleep, anthropometric data, Mallampati score and Epworth sleepiness scale (ESS) using the Apnea Link device. Undiagnosed SA was found in 72.9% patients (29.3% mild, 26.6% moderate, 17.0% severe) of 188 patients with NH measured by ABPM...
January 5, 2018: Physiological Research
https://www.readbyqxmd.com/read/29283931/resistance-exercise-training-is-more-effective-than-interval-aerobic-training-in-reducing-blood-pressure-during-sleep-in-hypertensive-elderly-patients
#16
Rodrigo F Bertani, Giulliard O Campos, Diego M Perseguin, José Bonardi, Eduardo Ferriolli, Julio C Moriguti, Nereida K C Lima
An appropriate fall in blood pressure (BP) during sleep is known to be related to a lower cardiovascular risk. The objective of the present study was to compare the effect of different types of training on hypertensive elderly patients under treatment in terms of pressure variability assessed by the nocturnal decline in BP. Hypertensive elderly subjects under pharmacological treatment were randomly assigned to the following groups: 12 weeks of continuous aerobic training (CA), interval aerobic training (IA), resistance training (R), or control (C)...
December 27, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29278556/discerning-the-relationship-between-left-ventricular-geometry-high-sensitivity-troponin-t-and-nondipper-hypertension
#17
Lutfu Askin, Hakan Tasolar, Ugur Aksu, Mustafa Cetin, Abdulkadir Uslu, Halil I Tanboga, Serdar Turkmen, Erdal Akturk
INTRODUCTION: Hypertension can cause anatomic changes in the left ventricle, generally leading to abnormal geometry. High-sensitivity cardiac troponin T (hs-cTnT) values have been shown to be positively correlated with left ventricular hypertrophy in hypertensive patients. The current study investigated the diagnostic value of hs-cTnT in patient with nondipper hypertension (NDH) as well as determined the correlation between left ventricular geometric patterns and hs-cTnT values in hypertensive patients...
February 2018: Blood Pressure Monitoring
https://www.readbyqxmd.com/read/29246398/doca-salt-hypertension-alters-period1-and-orexin-related-gene-expression-in-the-medulla-and-hypothalamus-of-male-rats-diurnal-influences
#18
M E Hernandez, J M Watkins, J Vu, L F Hayward
In peripheral tissues, aldosterone alters expression of multiple genes, including the clock gene Period 1 (Per1), 11 beta-hydroxysteroid dehydrogenase-2 (11-HSD2), and α-ENAC, the epithelial sodium channel subunit. We evaluated the impact of chronic aldosterone exposure (DOCA) and salt intake on nocturnal changes in gene expression in the male Sprague Dawley rat brain. Additionally, genes associated with the orexin (ORX) system were also evaluated based on the role of this neuropeptide in arousal, feeding and hypertension and an interconnection with Per1 expression...
December 9, 2017: Autonomic Neuroscience: Basic & Clinical
https://www.readbyqxmd.com/read/29240959/evaluation-of-left-ventricular-function-in-overweight-children-and-teenagers-with-arterial-hypertension-and-white-coat-hypertension
#19
Tomasz Florianczyk, Malgorzata Golabek-Dylewska, Beata Kucinska, Bozena Werner
BACKGROUND: Obesity in childhood is strongly associated with elevated arterial blood pressure and risk of hypertension. The aim of the study was the evaluation of left ventricular function in hypertensive and white coat hypertensive overweight children and teenagers. METHODS: The study group consisted of 74 overweight patients aged 10.3 ± 3.1 years (range: 6-16 years) diagnosed as hypertensive in standard blood pressure measurement. The control group consisted of 31 normotensive and normoweight children...
December 14, 2017: Cardiology Journal
https://www.readbyqxmd.com/read/29240564/evaluating-different-criteria-for-defining-a-complete-ambulatory-blood-pressure-monitoring-recording-data-from-the-jackson-heart-study
#20
Samantha G Bromfield, John N Booth, Matthew S Loop, Joseph E Schwartz, Samantha R Seals, Stephen J Thomas, Yuan-I Min, Gbenga Ogedegbe, Daichi Shimbo, Paul Muntner
OBJECTIVE: We determined differences in the prevalence of blood pressure (BP) phenotypes and the association of these phenotypes with left ventricular hypertrophy (LVH) for individuals who fulfilled and did not fulfill various criteria used for defining a complete ambulatory blood pressure monitoring (ABPM) recording. METHODS: We analyzed data for 1141 participants from the Jackson Heart Study. Criteria evaluated included having greater than or equal to 80% of planned readings with more than or equal to one reading per hour (Spanish ABPM Registry criteria), more than or equal to 70% of planned readings with a minimum of 20 daytime and seven nighttime readings (2013 European Society of Hypertension criteria), greater than or equal to 14 daytime and greater than or equal to seven nighttime readings (2003 European Society of Hypertension criteria), more than or equal to 10 daytime and more than or equal to 5 nighttime readings (International Database of Ambulatory Blood Pressure in Relation to Cardiovascular Outcome criteria), and greater than or equal to 14 daytime readings (UK National Institute of Health and Clinical Excellence criteria)...
December 13, 2017: Blood Pressure Monitoring
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