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https://www.readbyqxmd.com/read/28827926/effects-of-yoga-in-managing-fatigue-in-breast-cancer-patients-a-randomized-controlled-trial
#1
H S Vadiraja, Raghavendra Mohan Rao, R Nagarathna, H R Nagendra, Shekhar Patil, Ravi B Diwakar, H P Shashidhara, K S Gopinath, B S Ajaikumar
BACKGROUND: Cancer-related fatigue is widely prevalent in cancer patients and affects quality of life in advanced cancer patients. Fatigue is caused due to both psychologic distress and physiological sequel following cancer progression and its treatment. In this study, we evaluate the effects of yogic intervention in managing fatigue in metastatic breast cancer patients. METHODS: Ninety-one patients with metastatic breast cancer were randomized to receive integrated yoga program (n = 46) or supportive therapy and education (n = 45) over a 3-month period...
July 2017: Indian Journal of Palliative Care
https://www.readbyqxmd.com/read/28821274/candidate-inflammatory-biomarkers-display-unique-relationships-with-alpha-synuclein-and-correlate-with-measures-of-disease-severity-in-subjects-with-parkinson-s-disease
#2
Lori N Eidson, George T Kannarkat, Christopher J Barnum, Jianjun Chang, Jaegwon Chung, Chelsea Caspell-Garcia, Peggy Taylor, Brit Mollenhauer, Michael G Schlossmacher, Larry Ereshefsky, Mark Yen, Catherine Kopil, Mark Frasier, Kenneth Marek, Vicki S Hertzberg, Malú G Tansey
BACKGROUND: Efforts to identify fluid biomarkers of Parkinson's disease (PD) have intensified in the last decade. As the role of inflammation in PD pathophysiology becomes increasingly recognized, investigators aim to define inflammatory signatures to help elucidate underlying mechanisms of disease pathogenesis and aid in identification of patients with inflammatory endophenotypes that could benefit from immunomodulatory interventions. However, discordant results in the literature and a lack of information regarding the stability of inflammatory factors over a 24-h period have hampered progress...
August 18, 2017: Journal of Neuroinflammation
https://www.readbyqxmd.com/read/28821248/morphology-of-the-snake-spectacle-reflects-its-evolutionary-adaptation-and-development
#3
Mari-Ann Otkjaer Da Silva, Steffen Heegaard, Tobias Wang, Jacob Thorup Gade, Christian Damsgaard, Mads Frost Bertelsen
BACKGROUND: Covering the eye of all snakes is a transparent integumental structure known as the spectacle. In order to determine variations in spectacle thickness among species, the spectacles of 217 alcohol-preserved museum specimens of 44 species belonging to 14 different families underwent optical coherence tomography (OCT) to measure spectacular thickness. Multivariable analyses were made to determine whether family, activity period (diurnal/nocturnal) and habitat (arboreal/terrestrial/fossorial/aquatic) influenced spectacle thickness...
August 18, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/28814720/seasonal-total-methane-depletion-in-limestone-caves
#4
Chris L Waring, Stuart I Hankin, David W T Griffith, Michael A Kertesz, Victoria Kobylski, Neil L Wilson, Nicholas V Coleman, Graham Kettlewell, Robert Zlot, Michael Bosse, Graham Bell
Methane concentration in caves is commonly much lower than the external atmosphere, yet the cave CH4 depletion causal mechanism is contested and dynamic links to external diurnal and seasonal temperature cycles unknown. Here, we report a continuous 3-year record of cave methane and other trace gases in Jenolan Caves, Australia which shows a seasonal cycle of extreme CH4 depletion, from ambient ~1,775 ppb to near zero during summer and to ~800 ppb in winter. Methanotrophic bacteria, some newly-discovered, rapidly consume methane on cave surfaces and in external karst soils with lifetimes in the cave of a few hours...
August 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28812168/a-wireless-pressure-sensor-for-continuous%C3%A2-monitoring-of-intraocular-pressure-in-conscious-animals
#5
Simon A Bello, Christopher L Passaglia
An important aspect of eye health in humans and animal models of human diseases is intraocular pressure (IOP). IOP is typically measured by hand with a tonometer, so data are sparse and sporadic and round-the-clock variations are not well characterized. Here we present a novel system for continuous wireless IOP and temperature measurement in small animals. The system consists of a cannula implanted in the anterior chamber of the eye connected to pressure sensing electronics that can be worn by rats or implanted in larger mammals...
August 15, 2017: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/28806070/high-levels-of-daytime-molecular-chlorine-and-nitryl-chloride-at-a-rural-site-on-the-north-china-plain
#6
Xiaoxi Liu, Hang Qu, Lewis Gregory Huey, Yuhang Wang, Steven Sjostedt, Limin Zeng, Keding Lu, Yusheng Wu, Min Hu, Min Shao, Tong Zhu, Yuanhang Zhang
Molecular chlorine (Cl2) and nitryl chloride (ClNO2) concentrations were measured using chemical ionization mass spectrometry at a rural site over the North China Plain during June 2014. High levels of daytime Cl2 up to ~450 pptv were observed. The average diurnal Cl2 mixing ratios showed a maximum around noon at ~100 pptv. ClNO2 exhibited a strong diurnal variation with early morning maxima reaching ppbv levels and afternoon minima sustained above 60 pptv. A moderate correlation (R(2)=0.31) between Cl2 and sulfur dioxide was observed, perhaps indicating a role for power plant emissions in the generation of the observed chlorine...
August 14, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28805639/development-and-evolution-of-brain-allometry-in-wasps-vespidae-size-ecology-and-sociality
#7
REVIEW
Sean O'Donnell, Susan Bulova
We review research on brain development and brain evolution in the wasp family Vespidae. Basic vespid neuroanatomy and some aspects of functional neural circuitry are well-characterized, and genomic tools for exploring brain plasticity are being developed. Although relatively modest in terms of species richness, the Vespidae include species spanning much of the known range of animal social complexity, from solitary nesters to highly eusocial species with some of the largest known colonies and multiple reproductives...
August 2017: Current Opinion in Insect Science
https://www.readbyqxmd.com/read/28799904/circadian-coordination-of-antimicrobial-responses
#8
REVIEW
Paola Tognini, Christoph A Thaiss, Eran Elinav, Paolo Sassone-Corsi
Microbial infection poses a threat to organismal homeostasis and therefore must be efficiently counteracted by host defense mechanisms. It has been recently demonstrated that the immune system may anticipate an emerging pathogenic exposure through a heightened inflammatory state. Such anticipatory responses to fluctuating environmental conditions are typically orchestrated by the circadian clock, an intrinsic time-keeping system that adapts tissue physiology to diurnal variations in external influences. Here, we review current knowledge about the interplay between the circadian clock and antimicrobial responses...
August 9, 2017: Cell Host & Microbe
https://www.readbyqxmd.com/read/28796527/role-of-leptin-in-obstructive-sleep-apnea
#9
Ikuyo Imayama, Bharati Prasad
Leptin is a peptide hormone mainly produced in white adipose tissue. It is known to regulate energy homeostasis, inflammation, metabolism, and sympathetic nerve activity. Increasing evidence suggests it has a role in ventilatory function and upper airway obstruction. Leptin levels correlate positively with measurements of adiposity and can potentially provide important insights into the pathophysiology of diseases associated with obesity. Obesity is a strong risk factor for obstructive sleep apnea, a disease characterized by periodic upper airway occlusion during sleep...
August 10, 2017: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/28792639/circadian-rhythms-vary-over-the-growing-season-and-correlate-with-fitness-components
#10
Matthew J Rubin, Marcus T Brock, Amanda M Davis, Zachary M German, Mary Knapp, Stephen M Welch, Stacey L Harmer, Julin N Maloof, Seth J Davis, Cynthia Weinig
Circadian clocks have evolved independently in all three domains of life, suggesting that internal mechanisms of time-keeping are adaptive in contemporary populations. However, the performance consequences of either discrete or quantitative clock variation have rarely been tested in field settings. Clock sensitivity of diverse segregating lines to the environment remains uncharacterized as do the statistical genetic parameters that determine evolutionary potential. In field studies with Arabidopsis thaliana, we found that major perturbations to circadian cycle length (referred to as clock period) via mutation reduce both survival and fecundity...
August 9, 2017: Molecular Ecology
https://www.readbyqxmd.com/read/28789932/the-effects-of-anandamide-and-oleamide-on-cognition-depend-on-diurnal-variations
#11
Pavel E Rueda-Orozco, Corinne J Montes-Rodriguez Cj, Alejandra E Ruiz-Contreras, Monica Mendez-Diaz, Oscar Prospero-Garcia
Cannabinergic receptor 1 (CB1r) is highly expressed in almost the entire brain; hence, its activation affects diverse functions, including cognitive processes such as learning and memory. On the other hand, it has been demonstrated that CB1r expression fluctuates along the light-dark cycle. In this context, the objective of this work was to characterize the cannabinergic influence over cognitive processes and its relationship with the light-dark cycle. To this aim we studied the effects of two endogenous cannabinoids, anandamide (AEA) and oleamide (ODA), on the consolidation of memory and event-related potentials (ERPs) depending on the light-dark cycle...
August 5, 2017: Brain Research
https://www.readbyqxmd.com/read/28781313/the-aggravation-of-depression-with-aging-in-japanese-patients-with-subacute-myelo-optico-neuropathy-smon
#12
Tetsuro Konishi, Kaori Hayashi, Hiroshi Sugiyama
Objective We attempted to clarify the factors related to the aggravation of depression in patients with subacute myelo-optico-neuropathy (SMON) caused by clioquinol intoxication more than 35 years previously. Methods We investigated changes in the depressive mental states that occurred with aging in 19 Japanese SMON patients (mean age, 78.3 years; range, 66-89 years) according to their scores on the Japanese version of the Zung Self-rating Depression Scale (SDS), which were obtained 3-10 years previously and their current scores...
August 1, 2017: Internal Medicine
https://www.readbyqxmd.com/read/28774294/temperature-variability-in-the-day-night-cycle-is-associated-with-further-intracranial-pressure-during-therapeutic-hypothermia
#13
Adriano Barreto Nogueira, Eva Annen, Oliver Boss, Faraneh Farokhzad, Christopher Sikorski, Emanuela Keller
BACKGROUND: To assess whether circadian patterns of temperature correlate with further values of intracranial pressure (ICP) in severe brain injury treated with hypothermia. METHODS: We retrospectively analyzed temperature values in subarachnoid hemorrhage patients treated with hypothermia by endovascular cooling. The circadian patterns of temperature were correlated with the mean ICP across the following day (ICP24). RESULTS: We analyzed data from 17 days of monitoring of three subarachnoid hemorrhage patients that underwent aneurysm coiling, sedation and hypothermia due to refractory intracranial hypertension and/or cerebral vasospasm...
August 3, 2017: Journal of Translational Medicine
https://www.readbyqxmd.com/read/28770063/seasonal-variation-in-basal-and-plastic-cold-tolerance-adaptation-is-influenced-by-both-long-and-short-term-phenotypic-plasticity
#14
Suegene Noh, Elizabeth R Everman, Christopher M Berger, Theodore J Morgan
Understanding how thermal selection affects phenotypic distributions across different time scales will allow us to predict the effect of climate change on the fitness of ectotherms. We tested how seasonal temperature variation affects basal levels of cold tolerance and two types of phenotypic plasticity in Drosophila melanogaster. Developmental acclimation occurs as developmental stages of an organism are exposed to seasonal changes in temperature and its effect is irreversible, while reversible short-term acclimation occurs daily in response to diurnal changes in temperature...
July 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/28762278/co-ingested-alcohol-and-the-timing-of-deliberate-self-poisonings
#15
Kate M Chitty, Katharine Kirby, Nicholas J Osborne, Geoffrey K Isbister, Nicholas A Buckley
OBJECTIVE: Investigating diurnal variation in the timing of suicidal behaviours offers opportunity to better understand its various proximal risk factors. Acute use of alcohol is a potent proximal risk factor for suicidal behaviour, though the nature of this risk is poorly understood. The aim of this study was to compare the diurnal variation in time of poison ingestion between deliberate self-poisonings that involve alcohol versus those that do not. METHODS: A retrospective analysis of consecutive presentations to a toxicology service following deliberate self-poisoning, 1996-2016...
July 1, 2017: Australian and New Zealand Journal of Psychiatry
https://www.readbyqxmd.com/read/28754607/reversal-of-nocturnal-non-dipping-of-blood-pressure-after-levothyroxine-therapy-in-patients-with-subclinical-hypothyroidism
#16
Mannmath Nath, Balram Gupta, Madhukar Rai, Surya K Singh
AIMS: To study the loss of diurnal variation in blood pressure in normotensive patients with Subclinical/overt hypothyroidism and effect of Levothyroxine (L-T4) treatment. MATERIALS AND METHODS: In this interventional study Eighty patients between 17- 50 years with newly detected OH and SCH (74 women and 6 men) and nine euthyroid subjects (all men) with blood pressure <140/90 were recruited. All patients underwent 24h ambulatory blood pressure monitoring (ABPM) using ABPM machine before and after treatment with L-T4...
July 20, 2017: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/28744291/a-model-of-silicon-dynamics-in-rice-an-analysis-of-the-investment-efficiency-of-si-transporters
#17
Gen Sakurai, Naoki Yamaji, Namiki Mitani-Ueno, Masayuki Yokozawa, Keisuke Ono, Jian Feng Ma
Silicon is the second most abundant element in soils and is beneficial for plant growth. Although, the localizations and polarities of rice Si transporters have been elucidated, the mechanisms that control the expression of Si transporter genes and the functional reasons for controlling expression are not well-understood. We developed a new model that simulates the dynamics of Si in the whole plant in rice by considering Si transport in the roots, distribution at the nodes, and signaling substances controlling transporter gene expression...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28738815/transcription-through-the-eye-of-a-needle-daily-and-annual-cyclic-gene-expression-variation-in-douglas-fir-needles
#18
Richard Cronn, Peter C Dolan, Sanjuro Jogdeo, Jill L Wegrzyn, David B Neale, J Bradley St Clair, Dee R Denver
BACKGROUND: Perennial growth in plants is the product of interdependent cycles of daily and annual stimuli that induce cycles of growth and dormancy. In conifers, needles are the key perennial organ that integrates daily and seasonal signals from light, temperature, and water availability. To understand the relationship between seasonal cycles and seasonal gene expression responses in conifers, we examined diurnal and circannual needle mRNA accumulation in Douglas-fir (Pseudotsuga menziesii) needles at diurnal and circannual scales...
July 24, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28735585/analyses-of-body-weight-patterns-in-growing-pigs-a-new-view-on-body-weight-in-pigs-for-frequent-monitoring
#19
A H Stygar, K A Dolecheck, A R Kristensen
Frequent BW monitoring of growing pigs can be useful for identifying production (e.g. feeding), health and welfare problems. However, in order to construct a tool which will properly recognize abnormalities in pigs' growth a precise description of the growth process should be used. In this study we proposed a new model of pig growth accounting for daily fluctuations in BW. Body weight measurements of 1710 pigs (865 gilts and 843 barrows) originating from five consecutive batches from a Danish commercial farm were collected...
July 24, 2017: Animal: An International Journal of Animal Bioscience
https://www.readbyqxmd.com/read/28735361/concentrations-source-identification-and-lung-cancer-risk-associated-with-springtime-pm2-5-bound-polycyclic-aromatic-hydrocarbons-pahs-in-nanjing-china
#20
Chong Chen, Zhonghuan Xia, Minmin Wu, Qianqian Zhang, Tao Wang, Liping Wang, Hao Yang
This study concentrated on the pollution level, sources, and lung cancer risk of PM2.5-bound polycyclic aromatic hydrocarbons (PAHs) in spring in Nanjing, China. The PM2.5 samples were collected in spring of the year 2016 in Nanjing. Sixteen United States Environmental Protection Agency priority PAHs were extracted and analyzed after sampling. The mean concentrations of PAHs and BaPeq were 3.98 ± 1.01 and 0.29 ± 0.08 ng/m(3), respectively, which is a low level among results from regions worldwide. The diurnal variations of PAHs and BaPeq concentrations showed a relatively high level in the early morning, at the morning rush time of work and traffic transportation, and in the evening traffic peak hours...
July 22, 2017: Archives of Environmental Contamination and Toxicology
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