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https://www.readbyqxmd.com/read/29342038/utility-of-noncontrast-magnetic-resonance-imaging-for-detection-of-recurrent-vestibular-schwannoma
#1
Jamie C Williams, Carrie M Carr, Laurence J Eckel, Amy L Kotsenas, Christopher H Hunt, Matthew L Carlson, John I Lane
BACKGROUND: Gadolinium-enhanced T1-weighted magnetic resonance imaging (MRI) (T1WI) is the conventional imaging technique of choice to detect vestibular schwannoma (VS) recurrence or regrowth, despite suboptimal specificity secondary to enhancing postoperative changes. Furthermore, recent concerns regarding the accumulation of gadolinium in body tissues have led for a call to reduce the number of contrast-enhanced examinations. The objective of the current study is to evaluate the diagnostic accuracy of high-resolution noncontrast (three-dimensional [3D] T2) MRI relative to gadolinium-enhanced T1WI in the detection of VS recurrence after resection...
January 16, 2018: Otology & Neurotology
https://www.readbyqxmd.com/read/29342020/editorial-spring-board-gender-composition-in-high-impact-general-surgery-journals-over-20-years
#2
Chelsea A Harris, Tanima Banerjee, Monica Cramer, Shannon Manz, Sarah T Ward, Justin Dimick, Dana A Telem
OBJECTIVE: To quantify gender composition of 10 high-impact general surgery journals, delineate how board composition has changed over time, and evaluate qualification metrics by gender. BACKGROUND: Underrepresentation of women on editorial boards may contribute to the gender-based achievement gap in surgery. METHODS: We performed a cross-sectional analysis of the editorial board gender composition among 10 high-impact general surgery journals in 1997, 2007, and 2017...
January 16, 2018: Annals of Surgery
https://www.readbyqxmd.com/read/29341033/-lung-volume-reduction-surgery
#3
C Caviezel, D Franzen, W Weder
Lung volume reduction surgery (LVRS) offers improvement in lung function, quality of life and even survival in well selected patients with severe emphysema. Patients with all types of emphysema morphology can profit from LVRS when certain selection criteria are present. Hyperinflation plays a key role in qualifying for the procedure. Candidate selection should be performed at high volume centers with a multidisciplinary emphysema board. Qualified thoracic surgeons together with pulmonologists and radiologists identify the suitable patient considering emphysema morphology with its target areas for resection, lung function parameters and cardiac comorbidities...
January 2018: Pneumologie
https://www.readbyqxmd.com/read/29340341/credentialing-of-hospitalists-in-ultrasound-guided-bedside-procedures-a-position-statement-of-the-society-of-hospital-medicine
#4
Brian P Lucas, David M Tierney, Trevor P Jensen, Ria Dancel, Joel Cho, Mahmoud El-Barbary, Ricardo Franco-Sadud, Nilam Soni
Ultrasound guidance is used increasingly to perform the following 6 bedside procedures that are core competencies of hospitalists: abdominal paracentesis, arterial catheter placement, arthrocentesis, central venous catheter placement, lumbar puncture, and thoracentesis. Yet most hospitalists have not been certified to perform these procedures, whether using ultrasound guidance or not, by specialty boards or other institutions extramural to their own hospitals. Instead, hospital privileging committees often ask hospitalist group leaders to make ad hoc intramural certification assessments as part of credentialing...
January 18, 2018: Journal of Hospital Medicine: An Official Publication of the Society of Hospital Medicine
https://www.readbyqxmd.com/read/29339222/measurement-variability-of-liver-metastases-from-neuroendocrine-tumors-on-different-magnetic-resonance-imaging-sequences
#5
T Lestra, L Kanagaratnam, S Mulé, A Janvier, H Brixi, G Cadiot, A Dohan, C Hoeffel
PURPOSE: To assess dimension measurement variability of liver metastases from neuroendocrine tumors (LMNET) on different magnetic resonance imaging (MRI) sequences. MATERIAL AND METHODS: In this institutional review board-approved retrospective study from January 2011 to December 2012, all liver MRI examinations performed at our department in patients with at least one measurable LMNET according to response evaluation criteria in solid tumors (RECIST1.1) were included...
January 12, 2018: Diagnostic and Interventional Imaging
https://www.readbyqxmd.com/read/29338291/indications-for-surgical-repair-of-type-1-laryngeal-cleft
#6
Craig E Berzofsky, Tali Lando, Sandra Ettema, Jennifer Nelson, Gayle Woodson
OBJECTIVES: Type 1 laryngeal cleft (T1LC) is a congenital deficiency in the posterior glottis, resulting in a communication between the hypopharynx and glottis. No consensus treatment paradigm exists for timing and criteria for patient selection for surgical repair. Our goal is to assess whether patient characteristics can help predict improvement after surgery. METHODS: After Institutional Review Board exemption, a retrospective chart review was performed for patients undergoing surgery to diagnose a T1LC...
January 1, 2018: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/29337841/frequency-and-severity-of-acute-allergic-like-reactions-to-intravenously-administered-gadolinium-based-contrast-media-in-children
#7
Monica M Forbes-Amrhein, Jonathan R Dillman, Andrew T Trout, Bernadette L Koch, Julie M Dickerson, Richard M Giordano, Alexander J Towbin
OBJECTIVES: The purpose of this study is to determine the frequency and severity of acute allergic-like reactions to gadolinium-based contrast media (GBCM) in children before, during, and after the transition from gadopentetate dimeglumine to gadoterate meglumine as our primary clinical GBCM. MATERIALS AND METHODS: Institutional review board approval was obtained for this Health Insurance Portability and Accountability Act-compliant retrospective investigation. Allergic-like reactions to GBCM in pediatric patients were retrospectively assessed from January 2009 to January 2017, which included a departmental change of GBCM from gadopentetate dimeglumine to gadoterate meglumine...
January 15, 2018: Investigative Radiology
https://www.readbyqxmd.com/read/29337660/guidance-for-evaluating-the-safety-of-experimental-releases-of-mosquitoes-emphasizing-mark-release-recapture-techniques
#8
Mark Q Benedict, J Derek Charlwood, Laura C Harrington, L Philip Lounibos, William K Reisen, Walter J Tabachnick
Experimental releases of mosquitoes are performed to understand characteristics of populations related to the biology, ability to transmit pathogens, and ultimately their control. In this article, we discuss considerations related to the safety of experimental releases of living mosquitoes, applying principles of good practice in vector biology that protect human health and comfort. We describe specific factors of experimental releases of mosquitoes that we believe are critical to inform institutional biosafety committees and similar review boards to which proposals to conduct mosquito release experiments have been submitted...
January 2018: Vector Borne and Zoonotic Diseases
https://www.readbyqxmd.com/read/29336660/current-practice-patterns-surrounding-fertility-concerns-in-stage-i-seminoma-patients-survey-of-united-states-radiation-oncologists
#9
Carl M Post, Aditya Jain, Catherine Degnin, Yiyi Chen, Mike Craycraft, Arthur Y Hung, Jerry J Jaboin, Charles R Thomas, Timur Mitin
PURPOSE: Patients with testicular seminoma may face fertility issues because of their underlying disease as well as treatments they undergo. The current patterns of practice among U.S. radiation oncologists aimed at assessing and preserving fertility in patients with Stage I seminoma are unknown. METHODS: We surveyed practicing U.S. radiation oncologists via an Institutional Review Board-approved online questionnaire. Respondents' characteristics and perceived patient infertility rates were analyzed for association with treatment recommendations...
January 16, 2018: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/29335347/smoking-is-the-most-significant-modifiable-lung-cancer-risk-factor-in-systemic-lupus-erythematosus
#10
Sasha Bernatsky, Rosalind Ramsey-Goldman, Michelle Petri, Murray B Urowitz, Dafna D Gladman, Paul R Fortin, Edward H Yelin, Ellen Ginzler, John G Hanly, Christine Peschken, Caroline Gordon, Ola Nived, Cynthia Aranow, Sang-Cheol Bae, David Isenberg, Anisur Rahman, James E Hansen, Yvan St Pierre, Ann E Clarke
OBJECTIVE: To assess lung cancer risk in systemic lupus erythematosus (SLE), relative to demographics, drug exposures, smoking, and disease activity. METHODS: We analyzed data from 14 SLE cohorts. We calculated adjusted HR estimates for lung cancer in SLE, relative to demographics, smoking, time-dependent medication exposures, and cumulative disease activity [mean adjusted SLE Disease Activity Index (SLEDAI) scores]. This project was approved by the ethics boards of all participating institutions, including the Institutional Review Board of the McGill University Health Centre...
January 15, 2018: Journal of Rheumatology
https://www.readbyqxmd.com/read/29333278/clinical-influence-of-exercise-therapy-on-sarcopenia-in-patients-with-chronic-pancreatitis-a-study-protocol-for-a-randomised-controlled-trial
#11
Kazunori Yoh, Hiroki Nishikawa, Hirayuki Enomoto, Yoshinori Iwata, Akio Ishii, Yukihisa Yuri, Noriko Ishii, Yuho Miyamoto, Kunihiro Hasegawa, Chikage Nakano, Ryo Takata, Takashi Nishimura, Nobuhiro Aizawa, Yoshiyuki Sakai, Naoto Ikeda, Tomoyuki Takashima, Hiroko Iijima, Shuhei Nishiguchi
Introduction and purpose: Chronic pancreatitis (CP) involves progressive inflammatory changes to the pancreas and can lead to permanent structural damage and impairment of both endocrine and exocrine functions. Current reports highlight a rise in the incidence and prevalence of CP. However, there is limited data currently available concerning patients with CP undergoing exercise therapy (ET). We aim to prospectively examine the influence of ET on sarcopenia in patients with CP. Methods and analysis: A detailed evaluation of the nutritional condition and the daily physical activities of each participant will be conducted prior to entering the study...
2018: BMJ Open Gastroenterology
https://www.readbyqxmd.com/read/29331975/is-postoperative-bracing-after-pedicle-screw-fixation-of-spine-fractures-necessary-study-protocol-of-the-ornot-study-a-randomised-controlled-multicentre-trial
#12
Arjen Johannes Smits, Jaap Deunk, Agnita Stadhouder, Mark Cornelis Altena, Diederik Hendrik Ruth Kempen, Frank Willem Bloemers
INTRODUCTION: The most common surgical treatment of traumatic spine fractures is through a posterior approach using pedicle screws and rods. Postoperative treatment protocols including the use of postoperative orthoses however differ between hospitals and surgeons. A three-point hyperextension orthosis is designed to support proper posture and unload the anterior column. Some motion remains when wearing an orthosis, and its main value in postoperative treatment is therefore believed to be pain relief and patient confidence...
January 13, 2018: BMJ Open
https://www.readbyqxmd.com/read/29331381/clinical-outcomes-of-first-line-abiraterone-acetate-or-enzalutamide-for-metastatic-castration-resistant-prostate-cancer-after-androgen-deprivation-therapy%C3%A2-docetaxel-or-adt-alone-for-metastatic-hormone-sensitive-prostate-cancer
#13
Edoardo Francini, Steven Yip, Shubidito Ahmed, Haocheng Li, Luke Ardolino, Carolyn P Evan, Marina Kaymakcalan, Grace K Shaw, Philip W Kantoff, Mary-Ellen Taplin, Nimira S Alimohamed, Anthony M Joshua, Daniel Y C Heng, Christopher J Sweeney
BACKGROUND: The CHAARTED (ChemoHormonal Therapy Versus Androgen Ablation Randomized Trial for Extensive Disease in Prostate Cancer) and STAMPEDE (Systemic Therapy in Advancing or Metastatic Prostate Cancer: Evaluation of Drug Efficacy) trials showed that the addition of docetaxel (D) to androgen deprivation therapy (ADT) prolonged longevity of men with metastatic hormone-sensitive prostate cancer (mHSPC). However, the impact of upfront D on subsequent therapies is still unexplored. As abiraterone acetate (AA) and enzalutamide (E) are the most commonly used first-line treatment for metastatic castration-resistant prostate cancer (mCRPC), we aimed to assess whether they maintained their efficacy after ADT+D versus ADT alone...
December 27, 2017: Clinical Genitourinary Cancer
https://www.readbyqxmd.com/read/29331053/renal-flow-and-microstructure-anisotropy-refmap-mri-in-normal-and-peritumoral-renal-tissue
#14
Andrea L Liu, Artem Mikheev, Henry Rusinek, William C Huang, James S Wysock, James S Babb, Thorsten Feiweier, David Stoffel, Hersh Chandarana, Eric E Sigmund
BACKGROUND: Diffusion-weighted imaging (DWI) provides insight into the pathophysiology underlying renal dysfunction. Variants of DWI include intravoxel incoherent motion (IVIM), which differentiates between microstructural diffusion and vascular or tubular flow, and diffusion tensor imaging (DTI), which quantifies diffusion directionality. PURPOSE: To investigate the reproducibility of joint IVIM-DTI and compare controls to presurgical renal mass patients. STUDY TYPE: Prospective cross-sectional...
January 13, 2018: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/29330247/frequency-and-criticality-of-diagnoses-in-family-medicine-practices-from-the-national-ambulatory-medical-care-survey-namcs
#15
Michael R Peabody, Thomas R O'Neill, Keith L Stelter, James C Puffer
BACKGROUND: Family medicine is a specialty of breadth, providing comprehensive health care for the individual and the family that integrates the broad scope of clinical, social, and behavioral sciences. As such, the scope of practice (SOP) for family medicine is extensive; however, over time many family physicians narrow their SOP. We sought to provide a nationally representative description of the most common and the most critical diagnoses that family physicians see in their practice...
January 2018: Journal of the American Board of Family Medicine: JABFM
https://www.readbyqxmd.com/read/29329733/association-between-leukoaraiosis-and-cerebral-blood-flow-territory-alteration-in-asymptomatic-internal-carotid-artery-stenosis
#16
Y-F Chen, Y-S Kuo, W-C Wu, S-C Tang, S-F Jiang
AIM: To test the hypothesis that leukoaraiosis (also known as white matter lesion) is associated with cerebral blood flow territory change as revealed by territorial arterial spin-labeling (TASL) magnetic resonance imaging (MRI) in patients with asymptomatic internal carotid artery stenosis (aICAS). MATERIALS AND METHODS: The institutional review board approved this study. Thirty-three patients with aICAS were included prospectively and divided into high-grade (ultrasonographic stenosis ≥70%, n=17) and low-grade (n=16) groups; 16 healthy subjects were also included...
January 9, 2018: Clinical Radiology
https://www.readbyqxmd.com/read/29327527/role-and-relevance-of-blood-pressure-variability-in-hypertension-related-co-morbidities
#17
Ashok Kumar, B C Kalmath, Georgi Abraham, Johann Christopher, Pln Kaparthi, Louie Fischer, Neeta Deshpande, N K Mishra, Praveen Raj, Rajesh Javerani, Ramesh Goyal, Reefa Dsouza, Shashank R Joshi
Despite maintaining mean blood pressure at optimal levels, cardiovascular complications still occur in hypertensive patients. Blood pressure variability (BPV) has been implicated as a prominent factor responsible for incurring this additional risk. In this review we attempted to generate a consensus on the importance of BPV in the hypertension management and to evaluate different therapeutic options available to reduce BPV. Panel comprising of 11 leading experts from India in different areas of clinical practice (including nephrology, diabetes and endocrinology, cardiology, and critical care medicine) was convened...
December 2017: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/29326184/assessing-the-effectiveness-of-a-patient-centred-computer-based-clinic-intervention-health-e-you-salud-itu-to-reduce-health-disparities-in-unintended-pregnancies-among-hispanic-adolescents-study-protocol-for-a-cluster-randomised-control-trial
#18
Kathleen P Tebb, Felicia Rodriguez, Lance M Pollack, Sang Leng Trieu, Loris Hwang, Maryjane Puffer, Sally Adams, Elizabeth M Ozer, Claire D Brindis
INTRODUCTION: Teen pregnancy rates in the USA remain higher than any other industrialised nation, and pregnancies among Hispanic adolescents are disproportionately high. Computer-based interventions represent a promising approach to address sexual health and contraceptive use disparities. Preliminary findings have demonstrated that the Health-E You/Salud iTu, computer application (app) is feasible to implement, acceptable to Latina adolescents and improves sexual health knowledge and interest in selecting an effective contraceptive method when used in conjunction with a healthcare visit...
January 10, 2018: BMJ Open
https://www.readbyqxmd.com/read/29324970/watson-for-oncology-and-breast-cancer-treatment-recommendations-agreement-with-an-expert-multidisciplinary-tumor-board
#19
S P Somashekhar, M-J Sepúlveda, S Puglielli, A D Norden, E H Shortliffe, C Rohit Kumar, A Rauthan, N Arun Kumar, P Patil, K Rhee, Y Ramya
Background: Breast cancer oncologists are challenged to personalize care with rapidly changing scientific evidence, drug approvals, and treatment guidelines. Artificial intelligence (AI) clinical decision-support systems (CDSSs) have the potential to help address this challenge. We report here the results of examining the level of agreement (concordance) between treatment recommendations made by the AI CDSS Watson for Oncology (WFO) and a multidisciplinary tumor board for breast cancer...
January 9, 2018: Annals of Oncology: Official Journal of the European Society for Medical Oncology
https://www.readbyqxmd.com/read/29324491/validation-of-a-second-generation-near-infrared-spectroscopy-monitor-in-children-with-congenital-heart-disease
#20
Viviane G Nasr, Lisa T Bergersen, Hung-Mo Lin, Paul B Benni, Rachel S Bernier, Michelle E Anderson, Barry D Kussman
BACKGROUND: Cerebral oximetry using near-infrared spectroscopy is a noninvasive optical technology to detect cerebral hypoxia-ischemia and develop interventions to prevent and ameliorate hypoxic brain injury. Cerebral oximeters are calibrated and validated by comparison of the near-infrared spectroscopy-measured cerebral O2 saturation (SctO2) to a "field" or reference O2 saturation (REF CX) calculated as a weighted average from arterial and jugular bulb oxygen saturations. In this study, we calibrated and validated the second-generation, 5 wavelength, FORE-SIGHT Elite with the medium sensor (source-detector separation 12 and 40 mm) for measurement of SctO2 in children with congenital heart disease...
January 9, 2018: Anesthesia and Analgesia
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