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https://www.readbyqxmd.com/read/28205138/kant-s-epigenesis-specificity-and-developmental-constraints
#1
Boris Demarest
In this paper, I argue that Kant adopted, throughout his career, a position that is much more akin to classical accounts of epigenesis, although he does reject the more radical forms of epigenesis proposed in his own time, and does make use of preformationist sounding terms. I argue that this is because Kant (1) thinks of what is pre-formed as a species, not an individual or a part of an individual; (2) has no qualm with the idea of a specific, teleological principle or force underlying generation, and conceives of germs and predispositions as specific constraints on such a principle or force...
March 2017: History and Philosophy of the Life Sciences
https://www.readbyqxmd.com/read/28199030/lessons-learned-from-the-science-of-caring-extending-the-reach-of-psychosocial-oncology-the-international-psycho-oncology-society-2016-sutherland-award-lecture
#2
Barry D Bultz
In medicine, referral to a medical oncology specialty is based on recent history, physical examination, pathology, surgery reports, imaging, blood work and the patient's vital signs. By contrast, referral to a psychosocial specialist has typically been based on the patients expressed request for psychosocial support or the health care team's observation of the patient's limited adjustment or poor coping with the diagnosis, treatment or end of life distress. These observations are usually based on clinical acumen not on metrics...
February 15, 2017: Psycho-oncology
https://www.readbyqxmd.com/read/28197407/tribulations-of-the-last-mile-sides-from-a-regional-program
#3
Victor J Del Rio Vilas, Mary J Freire de Carvalho, Marco A N Vigilato, Felipe Rocha, Alexandra Vokaty, Julio A Pompei, Baldomero Molina Flores, Natael Fenelon, Ottorino Cosivi
In Latin American and Caribbean (LAC) countries, the number of cases of dog-mediated human rabies is at its lowest since the onset of the Regional Program for Rabies Elimination in 1983, a commitment from LAC countries to eliminate dog-mediated rabies coordinated by the Pan American Health Organization. Despite minor setbacks, the decline in the number of human cases has been constant since 1983. While many LAC countries have significantly reduced rabies to a level where it is no longer significant public health concern, elimination has proven elusive and pockets of the disease remain across the region...
2017: Frontiers in Veterinary Science
https://www.readbyqxmd.com/read/28196790/screening-for-child-sexual-exploitation-in-online-sexual-health-services-an-exploratory-study-of-expert-views
#4
Victoria Spencer-Hughes, Jonathan Syred, Alison Allison, Gillian Holdsworth, Paula Baraitser
BACKGROUND: Sexual health services routinely screen for child sexual exploitation (CSE). Although sexual health services are increasingly provided online, there has been no research on the translation of the safeguarding function to online services. We studied expert practitioner views on safeguarding in this context. OBJECTIVE: The aim was to document expert practitioner views on safeguarding in the context of an online sexual health service. METHODS: We conducted semistructured interviews with lead professionals purposively sampled from local, regional, or national organizations with a direct influence over CSE protocols, child protection policies, and sexual health services...
February 14, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28196562/deference-to-expertise-making-care-safer
#5
Gwendolyn Cherese Godlock, Rebecca Suzie Miltner, Dori Taylor Sullivan
Since the seminal report by the Institute of Medicine, To Err Is Human, was issued in 1999, significant efforts across the health care industry have been launched to improve the safety and quality of patient care. Recent advances in the safety of health care delivery have included commitment to creating high-reliability organizations (HROs) to enhance existing quality improvement activities. This article will explore key elements of the HRO concept of deference to expertise, describe the structural elements that support nurses and other personnel in speaking up, and provide examples of practical, evidence-based tools to help organizations support and encourage all members of the health care team to speak up...
February 1, 2017: Creative Nursing
https://www.readbyqxmd.com/read/28195249/building-blocks-of-the-gipu-italian-group-of-ultrastructural-pathology
#6
V Papa, R Costa, G Cenacchi
The Italian Group of Ultrastructural Pathology, GIPU, is a scientific organization committed to promote the art and science of Electron Microscopy (EM) in the pathology field in Italy, sharing its professional work with a public audience. The history of the GIPU goes back to 1990s when a founder group set up the Italian Group of Ultrastructural Diagnostic (GIDU) in Milan. The central focus of annual meetings was on EM, transmission and scanning one, about interesting cases in which it was instrumental in diagnosis...
June 2016: Pathologica
https://www.readbyqxmd.com/read/28186481/nursing-care-perspectives-and-foresights
#7
Didier Lecordier, Ljiljana Jovic
As a continuation of its work and of the seminar on nursing sciences education in 2014, the “Association de recherche en soins infirmiers” (Arsi) organized a seminar on the 3rd and-4th of June 2016 in Nantes entitled : “nursing : perspectives and foresights”. More than fifty participants from the francophone area representing various sectors of practice : clinical, teaching, management and students gathered to debate and produce benchmarks to support the development of nursing sciences in France and to draw future directions for clinical practice and training...
1, 2016: Recherche en Soins Infirmiers
https://www.readbyqxmd.com/read/28185618/tuberculosis-a-world-health-organization-perspective
#8
Giovanni Sotgiu, Giorgia Sulis, Alberto Matteelli
Tuberculosis (TB) is an important cause of morbidity and mortality worldwide. The World Health Organization (WHO) has implemented and scaled-up three important global public health strategies (i.e., DOTS, Stop TB, and End TB) to improve the international scenario. Their epidemiological impact was relevant, as they decreased the number of potential new cases of disease and death. However, the emergence and spread of TB/HIV coinfection and multidrug-resistant TB have hindered the progress towards the elimination of TB by 2050...
January 2017: Microbiology Spectrum
https://www.readbyqxmd.com/read/28181481/dpath-software-reveals-hierarchical-haemato-endothelial-lineages-of-etv2-progenitors-based-on-single-cell-transcriptome-analysis
#9
Wuming Gong, Tara L Rasmussen, Bhairab N Singh, Naoko Koyano-Nakagawa, Wei Pan, Daniel J Garry
Developmental, stem cell and cancer biologists are interested in the molecular definition of cellular differentiation. Although single-cell RNA sequencing represents a transformational advance for global gene analyses, novel obstacles have emerged, including the computational management of dropout events, the reconstruction of biological pathways and the isolation of target cell populations. We develop an algorithm named dpath that applies the concept of metagene entropy and allows the ranking of cells based on their differentiation potential...
February 9, 2017: Nature Communications
https://www.readbyqxmd.com/read/28170413/baseline-assessment-of-who-s-target-for-both-availability-and-affordability-of-essential-medicines-to-treat-non-communicable-diseases
#10
Margaret Ewen, Marjolein Zweekhorst, Barbara Regeer, Richard Laing
BACKGROUND: WHO has set a voluntary target of 80% availability of affordable essential medicines, including generics, to treat major non-communicable diseases (NCDs), in the public and private sectors of countries by 2025. We undertook a secondary analysis of data from 30 surveys in low- and middle-income countries, conducted from 2008-2015 using the World Health Organization (WHO)/Health Action International (HAI) medicine availability and price survey methodology, to establish a baseline for this target...
2017: PloS One
https://www.readbyqxmd.com/read/28168004/training-needs-and-perspectives-of-community-health-workers-in-relation-to-integrating-child-mental-health-care-into-primary-health-care-in-a-rural-setting-in-sub-saharan-africa-a-mixed-methods-study
#11
Dejene Tilahun, Charlotte Hanlon, Mesfin Araya, Basiro Davey, Rosa A Hoekstra, Abebaw Fekadu
BACKGROUND: Community health workers can help to address the substantial unmet need for child mental health care in low and middle income countries. However, little is known about their training needs for this potential role. The aim of this study was to examine training needs and perspectives of community health extension workers (HEWs) in relation to providing child mental health care in rural Ethiopia. METHODS: The study was conducted in the Southern Nations, Nationalities and Peoples' Region of Ethiopia...
2017: International Journal of Mental Health Systems
https://www.readbyqxmd.com/read/28166897/field-tests-of-a-participatory-ergonomics-toolkit-for-total-worker-health
#12
Suzanne Nobrega, Laura Kernan, Bora Plaku-Alakbarova, Michelle Robertson, Nicholas Warren, Robert Henning
Growing interest in Total Worker Health(®) (TWH) programs to advance worker safety, health and well-being motivated development of a toolkit to guide their implementation. Iterative design of a program toolkit occurred in which participatory ergonomics (PE) served as the primary basis to plan integrated TWH interventions in four diverse organizations. The toolkit provided start-up guides for committee formation and training, and a structured PE process for generating integrated TWH interventions. Process data from program facilitators and participants throughout program implementation were used for iterative toolkit design...
April 2017: Applied Ergonomics
https://www.readbyqxmd.com/read/28163799/psychological-well-being-among-religious-and-spiritual-identified-young-gay-and-bisexual-men
#13
Steven Meanley, Emily S Pingel, José A Bauermeister
Religiosity and spirituality are often integral facets of human development. Young gay and bisexual men (YGBM), however, may find themselves at odds when attempting to reconcile potentially conflicting identities like religion and their sexual orientation. We sought to explore how different components of religiosity (participation, commitment, spiritual coping) are linked to different markers of psychological well-being (life purpose, self-esteem, and internalized homophobia). Using data collected in Metro Detroit (N = 351 ages 18-29 years; 47% African American, 29% Non-Latino White, 8% Latino, 16% Other Race), we examined how components of religiosity/spirituality were associated with psychological well-being among religious/spiritual-identified participants...
March 2016: Sexuality Research & Social Policy: Journal of NSRC: SR & SP
https://www.readbyqxmd.com/read/28163061/importins-in-the-maintenance-and-lineage-commitment-of-es-cells
#14
REVIEW
Noriko Yasuhara, Yoshihiro Yoneda
The nucleus of a eukaryotic cell is separated from the cytoplasm by a nuclear envelope, and nuclear pores within the envelope facilitate nucleocytoplasmic transport and the exchange of information. Gene regulation is a key component of biological activity regulation in the cell. Transcription factors control the expression levels of various genes that are necessary for the maintenance or conversion of cellular states during animal development. Because transcription factor activities determine the extent of transcription of target genes, the number of active transcription factors must be tightly regulated...
February 2, 2017: Neurochemistry International
https://www.readbyqxmd.com/read/28161574/covalent-growth-factor-tethering-to-direct-neural-stem-cell-differentiation-and-self-organization
#15
Trevor R Ham, Mahmoud Farrag, Nic D Leipzig
: Tethered growth factors offer exciting new possibilities for guiding stem cell behavior. However, many of the current methods present substantial drawbacks which can limit their application and confound results. In this work, we developed a new method for the site-specific covalent immobilization of azide-tagged growth factors and investigated its utility in a model system for guiding neural stem cell (NSC) behavior. An engineered interferon-γ (IFN-γ) fusion protein was tagged with an N-terminal azide group, and immobilized to two different dibenzocyclooctyne-functionalized biomimetic polysaccharides (chitosan and hyaluronan)...
February 2, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28159132/-if-really-we-are-committed-things-can-change-starting-from-us-healthcare-providers-perceptions-of-postpartum-care-and-its-potential-for-improvement-in-low-income-suburbs-in-dar-es-salaam-tanzania
#16
Eunice N Pallangyo, Columba Mbekenga, Carina Källestål, Christine Rubertsson, Pia Olsson
OBJECTIVE: To explore healthcare providers' perceptions of the current postpartum care (PPC) practice and its potential for improvement at governmental health institutions in low-resource suburbs in Dar es Salaam, Tanzania. DESIGN: Qualitative design, using focus group discussions (8) and qualitative content analysis. SETTING: Healthcare institutions (8) at three levels of governmental healthcare in Ilala and Temeke suburbs, Dar es Salaam...
March 2017: Sexual & Reproductive Healthcare: Official Journal of the Swedish Association of Midwives
https://www.readbyqxmd.com/read/28144901/investigating-public-trust-in-expert-knowledge-narrative-ethics-and-engagement
#17
Silvia Camporesi, Maria Vaccarella, Mark Davis
"Public Trust in Expert Knowledge: Narrative, Ethics, and Engagement" examines the social, cultural, and ethical ramifications of changing public trust in the expert biomedical knowledge systems of emergent and complex global societies. This symposium was conceived as an interdisciplinary project, drawing on bioethics, the social sciences, and the medical humanities. We settled on public trust as a topic for our work together because its problematization cuts across our fields and substantive research interests...
January 31, 2017: Journal of Bioethical Inquiry
https://www.readbyqxmd.com/read/28141755/case-management-and-the-documentation-of-avoidable-days
#18
Leah N Shelerud, Jana L Esden
PURPOSE OF STUDY: Avoidable Days/Delays (ADs) account for a large portion of dollars lost for many health care organizations, and with ongoing changes in health care reimbursement, available funds will become increasingly limited. Avoidable Days cannot be reduced or eliminated without accurate causal documentation. The purpose of this study was to determine whether a system upgrade with a change in documentation layout for AD tracking increased case manager compliance with AD documentation...
March 2017: Professional Case Management
https://www.readbyqxmd.com/read/28139155/nurses-experiences-of-the-use-of-an-internet-based-support-system-for-adolescents-with-depressive-disorders
#19
Marjo Kurki, Minna Anttila, Marita Koivunen, Mauri Marttunen, Maritta Välimäki
BACKGROUND: Internet-based applications are potentially useful and effective interventions to reach and support adolescents with mental health problems. Adolescents' commitment to the use of a new Internet-based intervention is closely related to the support they receive from healthcare professionals. This study describes nurses' experiences of the use of an Internet-based support system for adolescents with depressive disorders. METHOD: Qualitative descriptive study design including individual interviews with nine nurses at two psychiatric outpatient clinics...
January 31, 2017: Informatics for Health & Social Care
https://www.readbyqxmd.com/read/28127543/national-action-plan-for-non-communicable-diseases-prevention-and-control-in-iran-a-response-to-emerging-epidemic
#20
REVIEW
Niloofar Peykari, Hassan Hashemi, Rasoul Dinarvand, Mohammad Haji-Aghajani, Reza Malekzadeh, Ali Sadrolsadat, Ali Akbar Sayyari, Mohsen Asadi-Lari, Alireza Delavari, Farshad Farzadfar, Aliakbar Haghdoost, Ramin Heshmat, Hamidreza Jamshidi, Naser Kalantari, Ahmad Koosha, Amirhossein Takian, Bagher Larijani
Emerging Non-communicable diseases burden move United Nation to call for 25% reduction by 2025 in premature mortality from non-communicable diseases (NCDs). The World Health Organization (WHO) developed global action plan for prevention and control NCDs, but the countries' contexts, priorities, and health care system might be different. Therefore, WHO expects from countries to meet national commitments to achieve the 25 by 25 goal through adapted targets and action plan. In this regards, sustainable high-level political statement plays a key role in rules and regulation support, and multi-sectoral collaborations to NCDs' prevention and control by considering the sustainable development goals and universal health coverage factors...
2017: Journal of Diabetes and Metabolic Disorders
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