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https://www.readbyqxmd.com/read/28393053/the-effect-of-topical-tranexamic-acid-on-bleeding-reduction-during-functional-endoscopic-sinus-surgery
#1
Mohammad Hossein Baradaranfar, Mohammad Hossein Dadgarnia, Hossein Mahmoudi, Nasim Behniafard, Saeid Atighechi, Vahid Zand, Amin Baradaranfar, Sedighe Vaziribozorg
INTRODUCTION: Bleeding is a common concern during functional endoscopic sinus surgery (FESS) that can increase the risk of damage to adjacent vital elements by reducing the surgeon's field of view. This study aimed to explore the efficacy of topical tranexamic acid in reducing intraoperative bleeding. MATERIALS AND METHODS: This double-blind, randomized clinical trial was conducted in 60 patients with chronic rhinosinusitis with polyposis (CRSwP) who underwent FESS...
March 2017: Iranian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/28382115/nasalance-changes-following-various-endonasal-surgeries
#2
Hazem Saeed Amer, Ahmed Shaker Elaassar, Ahmad Mohammad Anany, Amal Saeed Quriba
Introduction There is change in nasalance post endonasal surgery which is not permanent. Objectives The objective of this study is to evaluate the long-term nasalance changes following different types of endonasal surgeries. Methods We included in this study patients who underwent sinonasal surgery at the Otorhinolaryngology Department in Zagazig University Hospitals from February 2015 until March 2016. We divided the patients into two groups according to the surgeries they underwent: Group (A) was the FESS group and group (B), the septoturbinoplasty group...
April 2017: International Archives of Otorhinolaryngology
https://www.readbyqxmd.com/read/28381324/quality-of-life-improvement-after-endoscopic-sinus-surgery-in-patients-with-obstructive-sleep-apnea
#3
Bobby A Tajudeen, Steven G Brooks, Carol H Yan, Edward C Kuan, Joseph S Schwartz, Jeffrey D Suh, James N Palmer, Nithin D Adappa
BACKGROUND: There is preliminary evidence that patients with chronic rhinosinusitis (CRS) and comorbid obstructive sleep apnea (OSA) have reduced quality-of-life (QOL) improvements after functional endoscopic sinus surgery (FESS) compared with patients without OSA. The effect of OSA severity on QOL improvement after FESS is unknown. OBJECTIVES: To better characterize the QOL improvement after FESS for patients with comorbid OSA and to assess whether QOL improvement is dependent on OSA severity...
March 1, 2017: Allergy & Rhinology
https://www.readbyqxmd.com/read/28296272/ergonomic-analysis-of-the-surgical-position-in-functional-endoscopic-sinus-surgery
#4
Vijay R Ramakrishnan, Benjamin M Milam
BACKGROUND: Ergonomics is the methodologic study of people's efficiency in their work environment and is based on anatomy, physiology, psychology, and engineering. Although highly studied in other work environments, little attention has been paid to surgeons until the landmark survey by Park et al in 2010. Many unique aspects of endoscopic surgery amplify task-related physical discomfort, and, because of these issues, we aimed to study the physical fatigue effects of functional endoscopic sinus surgery (FESS) performed in the standing and sitting positions...
March 15, 2017: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/28286685/acute-vision-loss-following-endoscopic-sinus-surgery
#5
Serena Byrd, Adnan S Hussaini, Jastin Antisdel
A 41-year-old female with a history of uterine cancer and Celiac and Raynaud's Disease presented to our institution with frequent migraines and nasal congestion. She underwent functional endoscopic sinus surgery (FESS) and experienced acute unilateral vision loss postoperatively. Rapid recognition of the etiology and effective treatment are paramount given the permanent and irreversible vision loss that can result. Arterial vasospasm following FESS is rare. Patients with autoimmune diseases have perhaps an increased risk for vasospasm secondary to an increased vasoreactive profile...
2017: Case Reports in Otolaryngology
https://www.readbyqxmd.com/read/28284452/advances-in-absorbable-biomaterials-and-nasal-packing
#6
REVIEW
Conner J Massey, Ameet Singh
Nasal biomaterials have been developed to improve postoperative outcomes after functional endoscopic sinus surgery (FESS). These products have been designed to overcome certain common complications in FESS, and to maximize patient comfort. This article evaluates the performance of nonabsorbable and absorbable packing with respect to these outcomes. The collected trials suggest superior performance of bioabsorbable packs compared with absorbable packs with respect to patient comfort. For hemostasis and wound healing, variation in performance metrics makes interstudy comparison difficult...
March 9, 2017: Otolaryngologic Clinics of North America
https://www.readbyqxmd.com/read/28268037/sexual-health-after-breast-cancer-recommendations-from-the-spanish-menopause-society-federaci%C3%A3-n-espa%C3%A3-ola-de-sociedades-de-sexolog%C3%A3-a-sociedad-espa%C3%A3-ola-de-m%C3%A3-dicos-de-atenci%C3%A3-n-primaria-and-sociedad-espa%C3%A3-ola-de-oncolog%C3%A3-a-m%C3%A3-dica
#7
REVIEW
Nicolás Mendoza, Francisca Molero, Fermín Criado, Mª Jesús Cornellana, Encarna González
Breast cancer is the most common cancer in women. As survival rates are increasing, the long-term health problems of survivors now need attention. Many survivors develop sexual disorders as a consequence of either the side-effects of treatment or induced menopause. A panel of experts from various Spanish scientific societies (Spanish Menopause Society, SMS; Federación Española de Sociedades de Sexología, FESS; Sociedad Española de Médicos de Atención Primaria, SEMERGEN; and Sociedad Española de Oncología Médica) met to develop recommendations for the management of sexual health in breast cancer survivors based on the best evidence available...
February 20, 2017: Maturitas
https://www.readbyqxmd.com/read/28267156/maltose-binding-protein-effectively-stabilizes-the-partially-closed-conformation-of-the-atp-binding-cassette-transporter-malfgk2
#8
Jingwei Weng, Shuo Gu, Xin Gao, Xuhui Huang, Wenning Wang
Maltose transporter MalFGK2 is a type-I importer in the ATP-binding cassette (ABC) transporter superfamily. Upon the binding of its periplasmic binding protein, MalE, the ATPase activity of MalFGK2 can be greatly enhanced. Crystal structures of the MalFGK2-MalE-maltose complex in a so-called "pretranslocation" ("pre-T") state with a partially closed conformation suggest that the formation of this MalE-stabilized intermediate state is a key step leading to the outward-facing catalytic state. On the contrary, crosslinking and fluorescence studies suggest that ATP binding alone is sufficient to promote the outward-facing catalytic state, thereby doubting the role of MalE binding...
March 7, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28247540/peak-nasal-inspiratory-flow-correlates-with-quality-of-life-in-functional-endoscopic-sinus-surgery
#9
K L Whitcroft, P J Andrews, P S Randhawa
OBJECTIVES: Whilst nasal function and airflow improve subjectively following functional endoscopic sinus surgery (FESS), a clinically useful and objective tool for quantifying such improvement is lacking. The peak nasal inspiratory flow (PNIF) metre offers convenient and objective measures of nasal patency. However, it has not yet been established whether changes in PNIF after surgery reflect changes in subjective disease burden. In this study we aimed to determine whether changes in PNIF correlate with commonly used subjective symptom and quality of life outcome measures following FESS for chronic rhinosinusitis (CRS)...
March 1, 2017: Clinical Otolaryngology
https://www.readbyqxmd.com/read/28239574/do-nasal-surgeries-affect-mucociliary-clearance
#10
Rajeshwary Aroor, Zainab Sunu Ali, K S Gangadhara Somayaji
The study was conducted to assess the impact of different nasal surgeries on the nasal mucociliary clearance mechanism. Mucociliary function of the nasal mucosa of patients who were undergoing various nasal surgeries was assessed by the Saccharin test by placing 5 mg saccharin granule on the anterior end of the inferior turbinate 1 day prior to the surgery. The time required for the test subject to experience a sweet taste was measured in minutes. Post-operatively the test was repeated 6 weeks after the surgery and the test times were compared...
March 2017: Indian Journal of Otolaryngology and Head and Neck Surgery
https://www.readbyqxmd.com/read/28160292/preoperative-%C3%AE-blockade-and-hypertension-in-the-first-hour-of-functional-endoscopic-sinus-surgery
#11
Samuel A Schechtman, Aileen P Wertz, Amy Shanks, Aleda Thompson, Kevin Tremper, Melissa A Pynnonen, David W Healy
OBJECTIVES/HYPOTHESIS: Local anesthetic with epinephrine is commonly injected into the nasal mucosa during functional endoscopic sinus surgery (FESS). Systemic absorption of epinephrine following local injection may occur, resulting in a mild sympathetic response. This study seeks to determine whether an exaggerated sympathetic response to epinephrine is demonstrated in patients undergoing FESS treated preoperatively with established pharmacologic beta (β) adrenoceptor blockade. STUDY DESIGN: A retrospective analysis of adult patients undergoing FESS at a tertiary care university hospital...
February 3, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28124658/significance-of-undissected-retromaxillary-air-cells-as-a-risk-factor-for-revision-endoscopic-sinus-surgery
#12
Edward C Kuan, Jon Mallen-St Clair, John W Frederick, Bobby A Tajudeen, Marilene B Wang, Richard J Harvey, Jeffrey D Suh
BACKGROUND: Retromaxillary air cells (RMC) are posterior ethmoid cells that separate the maxillary and ethmoid sinuses. The clinical significance of these cells in contributing to revision functional endoscopic sinus surgery (FESS) is unknown. OBJECTIVES: To investigate the prevalence, anatomic dimensions, and radiographic characteristics of RMC in patients with recalcitrant chronic rhinosinusitis after previous FESS. METHODS: A retrospective review of patients who underwent revision FESS at a tertiary medical center between January 1, 2012, and December 31, 2014...
November 1, 2016: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/28060384/effects-of-functional-endoscopic-sinus-surgery-on-the-acoustics-of-the-sinonasal-tract
#13
M Havel, S Becker, M Schuster, T Johnson, A Maier, J Sundberg
BACKGROUND: Nasal and paranasal cavities are supposed to contribute substantially to the vocal tract resonator properties. However, their acoustical effects as well as the effects of sinus surgery on the voice remain unclear. In this work we investigate resonance phenomena of paranasal sinuses prior to and after various rhinosurgical procedures in cadaveric human sinonasal tracts and corresponding 3D casts. METHODOLOGY: Nasal and paranasal cavities of formalin-preserved cadavers and corresponding 3D replicas were excited by sine-tone sweeps from an earphone placed in the epipharynx...
March 1, 2017: Rhinology
https://www.readbyqxmd.com/read/28050473/evaluation-of-sinonasal-diseases-by-computed-tomography
#14
Rashmi Kandukuri, Suresh Phatak
INTRODUCTION: Computed Tomography (CT) plays an important diagnostic role in patients with sinonasal diseases and determines the treatment. The CT images clearly show fine structural architecture of bony anatomy thereby determining various anatomical variation, extent of disease and characterization of various inflammatory, benign and malignant sinonasal diseases. AIM: To evaluate sensitivity and specificity of CT in diagnosis of sinonasal diseases and to characterise the benign and malignant lesions with the help of various CT parameters...
November 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28026837/trigeminal-sensitivity-in-chronic-rhinosinusitis-topographical-differences-and-the-effect-of-surgery
#15
S C Poletti, M Cuevas, S Weile, T Hummel
INTRODUCTION: Little is known on endonasal trigeminal sensitivity in patients with chronic rhinosinusitis with nasal polyps (CRSwNP). The aim of our study was to investigate changes in trigeminal sensitivity in patients with CRSwNP and the effect of functional endoscopic sinus surgery (FESS) on trigeminal perception. METHODS: A prospective study was performed to investigate the trigeminal sensitivity at three different locations within the nose (anterior septum, anterior lateral wall, middle turbinate) using electrical stimuli...
March 1, 2017: Rhinology
https://www.readbyqxmd.com/read/28004527/efficacy-of-balloon-sinuplasty-in-treatment-of-frontal-rhinosinusitis-a-prospective-study-in-sixty-patients
#16
LETTER
P F Bowles, S Agrawal, M A Salam
No abstract text is available yet for this article.
December 22, 2016: Clinical Otolaryngology
https://www.readbyqxmd.com/read/27935538/the-correlation-of-tas2r38-gene-variants-with-higher-risk-for-chronic-rhinosinusitis-in-polish-patients
#17
Karolina Dżaman, Mariola Zagor, Elżbieta Sarnowska, Antoni Krzeski, Ireneusz Kantor
BACKGROUND: Bitter taste receptors (T2Rs), especially T2R38s appear as innovative regulators of innate immunity in the respiratory system. The single nucleotide polymorphisms (SNPs) in TAS2R38 gene may contribute to individual differences in susceptibility to respiratory infections especially chronic rhinosinusitis (CRS). TAS2R38 genotypes distribution varies by geographic region, race and ethnicity. The aim of the preliminary study was the identification of SNPs in TAS2R38 encoding genes in Polish patients with CRS and finding potential correlation with CRS phenotypes...
October 31, 2016: Otolaryngologia Polska
https://www.readbyqxmd.com/read/27888473/nasal-mucosa-healing-after-endoscopic-sinus-surgery-in-chronic-rhinosinusitis-of-elderly-patients-role-of-topic-alpha-tocopherol-acetate
#18
Domenico Testa, Giuseppina Marcuccio, Giorgio Panin, Andrea Bianco, Domenico Tafuri, Francesco Zappoli Thyrion, Michele Nunziata, Pasquale Piombino, Germano Guerra, Gaetano Motta
BACKGROUND: Chronic rhinosinusitis (CRS) in European country ranges in elderly patients from 4.5 to 12% of population and has a significant effect on quality of life. In these patients, rhinosinusitis is linked to immune functions changes with age and to mucosal paraphysiological alterations such as crusting formations with atrophic epithelium, variations of nasal airflow and modifications of the mucociliary clearance. Failure of medical treatments leads to surgery in patients with persistent symptoms and radiographic signs of CRS...
November 25, 2016: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/27846022/postoperative-care-in-endoscopic-sinus-surgery-a-critical-review
#19
Philippe Eloy, Peter Andrews, Anne-Lise Poirrier
PURPOSE OF REVIEW: Chronic rhinosinusitis with and without nasal polyps is a common disease affecting people all over the world. Functional endoscopic sinus surgery (FESS) has become the gold standard treatment for medically refractive disease. Postoperative care is recommended by international leaders as an important part of the patient's management. This article is a critical review and discussion focusing on postoperative care, which is based on expert opinion, clinical studies, randomized controlled trials and meta-analysis studies...
February 2017: Current Opinion in Otolaryngology & Head and Neck Surgery
https://www.readbyqxmd.com/read/27844221/moroccan-adaptation-and-validation-of-the-rhinosinusitis-quality-of-life-survey
#20
Taoufik Adouly, Choaib Adnane, Amine Khallouk, Meriem Chenguir, Sami Rouadi, Reda Lah Abada, Mohamed Roubal, Mohamed Mahtar
The aim of this study was to validate the Moroccan translation and sociocultural adaptation of the RhinoQOL questionnaire. The questionnaires were translated into Moroccan and then translated back into English. The final version was administered twice to an asymptomatic control population (n = 50) and once to a patients with chronic rhinosinusitis (CRS) undergoing functional endoscopic sinus surgery (FESS) (n = 99). Both of the groups answered the questionnaire before and one year after surgery. The psychometric properties, reliability, validity with correlation to other clinical instruments and responsiveness to treatment, were analyzed...
November 14, 2016: European Archives of Oto-rhino-laryngology
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