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Intracranial pressure

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https://www.readbyqxmd.com/read/28323775/inadequate-antioxidative-responses-in-kidneys-of-brain-dead-rats
#1
Dane Hoeksma, Rolando A Rebolledo, Maximilia Hottenrott, Yves S Bodar, Janneke J Wiersema-Buist, Harry Van Goor, Henri G D Leuvenink
BACKGROUND: Brain death (BD)-related lipid peroxidation, measured as serum malondialdehyde (MDA) levels, correlates with delayed graft function in renal transplant recipients. How BD affects lipid peroxidation is not known. The extent of BD-induced organ damage is influenced by the speed at which intracranial pressure increases. To determine possible underlying causes of lipid peroxidation, we investigated the renal redox balance by assessing oxidative and antioxidative processes in kidneys of brain-dead rats after fast and slow BD induction...
April 2017: Transplantation
https://www.readbyqxmd.com/read/28320145/vision-loss-in-tuberculous-meningitis
#2
REVIEW
Ravindra Kumar Garg, Hardeep Singh Malhotra, Neeraj Kumar, Ravi Uniyal
Vision loss is a disabling complication of tuberculous meningitis. Approximately, 15% of survivors are either completely or partially blind. All structures of the visual pathway may be affected in tuberculous meningitis. Optic nerve and optic chiasma are most frequently and dominantly affected. Thick-gelatinous exudates lying over the base of brain, are the pathological hallmark of tuberculous meningitis and are responsible for almost all of its major complications, including vision loss. Strangulation of optic nerves and optic chiasma by the exudates, compression over optic chiasma by the dilated third ventricle, raised intracranial pressure, endarteritis, shunt failure, bacterial invasion of optic nerves and drug-induced optic nerve damage are important reasons that are considered responsible for vision loss...
April 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28320134/post-hemorrhagic-hydrocephalus-recent-advances-and-new-therapeutic-insights
#3
REVIEW
Qianwei Chen, Zhou Feng, Qiang Tan, Jing Guo, Jun Tang, Liang Tan, Hua Feng, Zhi Chen
Post-hemorrhagic hydrocephalus (PHH), also referred to as progressive ventricular dilatation, is caused by disturbances in cerebrospinal fluid (CSF) flow or absorption following hemorrhage in the brain. As one of the most serious complications of neonatal/adult intraventricular hemorrhage (IVH), subarachnoid hemorrhage (SAH), and traumatic brain injury (TBI), PHH is associated with increased morbidity and disability of these events. Common sequelae of PHH include neurocognitive impairment, motor dysfunction, and growth impairment...
April 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28304189/physiological-remodeling-of-bifurcation-aneurysms-preclinical-results-of-the-eclips-device
#4
Thomas R Marotta, Howard A Riina, Ian McDougall, Donald R Ricci, Monika Killer-Oberpfalzer
OBJECTIVE Intracranial bifurcation aneurysms are complex lesions for which current therapy, including simple coiling, balloon- or stent-assisted coiling, coil retention, or intrasaccular devices, is inadequate. Thromboembolic complications due to a large burden of intraluminal metal, impedance of access to side branches, and a high recurrence rate, due largely to the unmitigated high-pressure flow into the aneurysm (water hammer effect), are among the limitations imposed by current therapy. The authors describe herein a novel device, eCLIPs, and its use in a preclinical laboratory study that suggests the device's design and functional features may overcome many of these limitations...
March 17, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28300719/idiopathic-intracranial-hypertension-in-monozygotic-female-twins-intracranial-pressure-dynamics-and-treatment-outcome
#5
Manolis Polemikos, Hans E Heissler, Elvis J Hermann, Joachim K Krauss
BACKGROUND: Familial cases of idiopathic intracranial hypertension (IIH) are exceedingly rare and its occurrence has not been reported before in monozygotic twins. CASE DESCRIPTION: We describe the cases of monozygotic female twins who developed IIH at age 25 and at age 28, respectively. Continuous intracranial pressure monitoring confirmed elevated intracranial pressure (ICP) as measured initially by lumbar puncture. In both cases, successful treatment with resolution of papilledema and symptoms relief was achieved after ventriculoperitoneal shunting...
March 11, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28298771/attenuation-of-hemodynamic-response-to-skull-pin-head-holder-insertion-intravenous-clonidine-versus-intravenous-lignocaine-infusion
#6
Nethra H Nanjundaswamy, Vinay Marulasiddappa
BACKGROUND: Insertion of skull pin induces a significant increase in heart rate (HR), blood pressure (BP) and intracranial pressure. Alpha 2 agonist clonidine and intravenous (i.v.) lignocaine are effective in attenuating stress response. Local infiltration of pin site and scalp block with lignocaine are commonly used techniques for prevention of hemodynamic response to skull pin insertion. We compared the effectiveness of i.v. clonidine infusion and i.v. lignocaine infusion in suppressing the hemodynamic response to skull pin head holder insertion...
January 2017: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/28297690/-multiple-tentorial-dural-arteriovenous-fistulas-with-acquired-pial-arteriovenous-fistula-presented-with-unilateral-eye-symptoms-successfully-treated-by-transarterial-embolization-and-direct-surgery-a-case-report
#7
Hisato Minamide, Yutaka Hayashi, Naoyuki Uchiyama
A 58-year-old man presented with slowly progressive chemosis, exophthalmos, and blepharedema of the left eye. Digital subtraction angiography revealed multiple dural arteriovenous fistulas(dAVFs)involving the bilateral tentorium, superior sagittal sinus, and right frontal convexity. In addition, occlusion of the left cavernous sinus and left sigmoid sinus were observed, which could lead to venous hypertension and might be associated with the occurrence of multiple dAVFs. Along with the congestion of the left ophthalmic vein, increased intracranial pressure due to the left tentorial dAVF with cortical venous reflux could have caused the left eye symptoms; therefore, the tentorial lesion was treated first...
March 2017: No Shinkei Geka. Neurological Surgery
https://www.readbyqxmd.com/read/28295370/the-human-endolymphatic-sac-expresses-natriuretic-peptides
#8
Martin Nue Møller, Svend Kirkeby, Jonas Vikeså, Finn Cilius Nielsen, Per Cayé-Thomasen
OBJECTIVES/HYPOTHESIS: The function of the human endolymphatic sac (ES) has been enigmatic for decades. Hypotheses include controlling endolymphatic fluid homeostasis and inner ear immunological defense. Additionally, several studies indicate a possible endocrine capacity and a yet undefined role in intracranial pressure homeostasis. However, no direct evidence of such capacity exists. This study aims to explore and identify the hypothesized endocrine capacity of the human ES. STUDY DESIGN: DNA microarrays and immunohistochemistry were used for analyses of fresh human ES tissue samples...
March 14, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28291455/measuring-hemodynamic-changes-in-the-ophthalmic-artery-during-applied-force-for-noninvasive-intracranial-pressure-monitoring-test-results-in-a-porcine-model
#9
Max Twedt, Chase Pfeifer, William Thorell, Greg Bashford
Possible traumatic brain injury victims would greatly benefit from a handheld, noninvasive intracranial pressure (ICP) monitoring tool, which a medic could operate in a remote area. Such a device would also benefit the transport of injured soldiers during en route medical care and critical care air transport. This study demonstrates the use of noninvasive blood flow measurements in the eye by ultrasound as a proxy for ICP. ICP was artificially raised in a porcine model and resultant blood flow change in the ophthalmic artery was measured...
March 2017: Military Medicine
https://www.readbyqxmd.com/read/28291128/the-use-of-ultrasound-in-obstetric-anesthesia
#10
Carolyn F Weiniger, Limor Sharoni
PURPOSE OF REVIEW: The current review considers an array of recent applications for point-of-care ultrasound in clinical practice including diagnostic and therapeutic procedures that may be relevant for the obstetric anesthesiologist. The rapid advancement of technology and clinical applications for bedside ultrasound in obstetric anesthesiology requires an appraisal of the limitations and uses. RECENT FINDINGS: The review presents the most recent literature describing ultrasound-guided airway assessments, airway management, cricothyroidotomy, transthoracic echocardiography, gastric volume assessments, point-of-care lung ultrasound diagnoses, intracranial pressure assessments, vascular access, neuraxial blocks, and transversus abdominis plane blocks...
March 11, 2017: Current Opinion in Anaesthesiology
https://www.readbyqxmd.com/read/28286027/creating-normograms-of-dural-sinuses-in-healthy-persons-using-computer-assisted-detection-for-analysis-and-comparison-of-cross-section-dural-sinuses-in-the-brain
#11
Reut Anconina, Dinah Zur, Anat Kesler, Svetlana Lublinsky, Ronen Toledano, Victor Novack, Elya Benkobich, Rosa Novoa, Evelyne Farkash Novic, Ilan Shelef
Dural sinuses vary in size and shape in many pathological conditions with abnormal intracranial pressure. Size and shape normograms of dural brain sinuses are not available. The creation of such normograms may enable computer-assisted comparison to pathologic exams and facilitate diagnoses. The purpose of this study was to quantitatively evaluate normal magnetic resonance venography (MRV) studies in order to create normograms of dural sinuses using a computerized algorithm for vessel cross-sectional analysis...
March 9, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28284189/changes-in-intraocular-pressure-and-optic-nerve-sheath-diameter-in-patients-undergoing-robotic-assisted-laparoscopic-prostatectomy-in-steep-45%C3%A2-trendelenburg-position
#12
Sebastian Blecha, Marion Harth, Felix Schlachetzki, Florian Zeman, Christiane Blecha, Pierre Flora, Maximilian Burger, Stefan Denzinger, Bernhard M Graf, Horst Helbig, Michael T Pawlik
BACKGROUND: To evaluate changes in intraocular pressure (IOP) and intracerebral pressure (ICP) reflected by the optic nerve sheath diameter (ONSD) in patients undergoing robotic-assisted laparoscopic prostatectomy (RALP) in permanent 45° steep Trendelenburg position (STP). METHODS: Fifty-one patients undergoing RALP under a standardised anaesthesia. IOP was perioperatively measured in awake patients (T0) and IOP and ONSD 20 min after induction of anaesthesia (T1), after insufflation of the abdomen in supine position (T2), after 30 min in STP (T3), when controlling Santorini's plexus in STP (T4) and before awakening while supine (T5)...
March 11, 2017: BMC Anesthesiology
https://www.readbyqxmd.com/read/28283997/decision-support-system-for-detection-of-papilledema-through-fundus-retinal-images
#13
Shahzad Akbar, Muhammad Usman Akram, Muhammad Sharif, Anam Tariq, Ubaid Ullah Yasin
A condition in which the optic nerve inside the eye is swelled due to increased intracranial pressure is known as papilledema. The abnormalities due to papilledema such as opacification of Retinal Nerve Fiber Layer (RNFL), dilated optic disc capillaries, blurred disc margins, absence of venous pulsations, elevation of optic disc, obscuration of optic disc vessels, dilation of optic disc veins, optic disc splinter hemorrhages, cotton wool spots and hard exudates may result in complete vision loss. The ophthalmologists detect papilledema by means of an ophthalmoscope, Computed Tomography (CT), Magnetic Resonance Imaging (MRI) and ultrasound...
April 2017: Journal of Medical Systems
https://www.readbyqxmd.com/read/28282851/twenty-four-hour-real-time-continuous-monitoring-of-cerebral-edema-in-rabbits-based-on-a-noninvasive-and-noncontact-system-of-magnetic-induction
#14
Gen Li, Ke Ma, Jian Sun, Gui Jin, Mingxin Qin, Hua Feng
Cerebral edema is a common disease, secondary to craniocerebral injury, and real-time continuous monitoring of cerebral edema is crucial for treating patients after traumatic brain injury. This work established a noninvasive and noncontact system by monitoring the magnetic induction phase shift (MIPS) which is associated with brain tissue conductivity. Sixteen rabbits (experimental group n = 10, control group, n = 6) were used to perform a 24 h MIPS and intracranial pressure (ICP) simultaneously monitored experimental study...
March 8, 2017: Sensors
https://www.readbyqxmd.com/read/28281221/evidence-for-decreased-brain-parenchymal-volume-after-large-intracerebral-hemorrhages-a-potential-mechanism-limiting-intracranial-pressure-rises
#15
Michael R Williamson, Frederick Colbourne
Potentially fatal intracranial pressure (ICP) rises commonly occur after large intracerebral hemorrhages (ICH). We monitored ICP after infusing 100-160 μL of autologous blood (vs. 0 μL control) into the striatum of rats in order to test the validity of this common model with regard to ICP elevations. Other endpoints included body temperature, behavioral impairment, lesion volume, and edema. Also, we evaluated hippocampal CA1 sector and somatosensory cortical neuron morphology to assess whether global ischemic injury occurred...
March 9, 2017: Translational Stroke Research
https://www.readbyqxmd.com/read/28280979/intensive-lowering-of-blood-pressure-in-the-acute-phase-of-intracranial-haemorrhage
#16
Viviana Bozzano, Tiziana Carandini
No abstract text is available yet for this article.
March 9, 2017: Internal and Emergency Medicine
https://www.readbyqxmd.com/read/28277554/morphological-changes-of-anterior-cerebral-artery-aca-in-hydrocephalic-pediatric-patients
#17
Sait Ozturk, Erdogan Ayan, Metin Kaplan
OBJECTIVE: The morphology of anterior cerebral artery (ACA) in patients with hydrocephalus (HCP) was analyzed, and its importance was discussed in maintaining cerebral perfusion. MATERIALS & METHODS: A total of 84 cases in 2 groups between 0 and 3 months, followed-up at Firat Universitesi Hastanesi, Beyin Cerrahisi Klinigi, Elazig, Turkiye due to in 2010-2013, were enrolled. Two groups were created for the study. Group 1; patients with HCP and Group 2; as control group without HCP...
2017: Iranian Journal of Child Neurology
https://www.readbyqxmd.com/read/28277451/intracranial-pressure-values-are-highly-variable-after-cerebral-spinal-fluid-drainage
#18
Wendy R Miller
No abstract text is available yet for this article.
April 2017: Journal of Neuroscience Nursing: Journal of the American Association of Neuroscience Nurses
https://www.readbyqxmd.com/read/28277450/intracranial-pressure-values-are-highly-variable-after-cerebral-spinal-fluid-drainage
#19
Michael Rogers, Sonja E Stutzman, Folefac D Atem, Samarpita Sengupta, Babu Welch, DaiWai M Olson
Intracranial pressure (ICP) is often obtained via external ventricular drain (EVD) placement and is discussed as a key vital sign in neuroscience. Nurses are most often delegated the task of observing, adjudicating, and documenting ICP. Cerebrospinal fluid drainage requires that the transducer connected to the EVD is open to drain, prohibiting ICP monitoring. There are no recent data to support an evidence-based standard for the period an ICP waveform should be observed, after the EVD is clamped, to be able to adjudicate a value that represents the patient's status...
April 2017: Journal of Neuroscience Nursing: Journal of the American Association of Neuroscience Nurses
https://www.readbyqxmd.com/read/28277415/mortality-risk-stratification-after-traumatic-brain-injury-and-hazard-of-death-with-titrated-hypothermia-in-the-eurotherm3235trial
#20
Peter J D Andrews, Aryelly Rodriguez, Peter Suter, Claire G Battison, Jonathan K J Rhodes, Irene Puddu, Bridget A Harris
OBJECTIVES: Hypothermia reduces intracranial hypertension in patients with traumatic brain injury but was associated with harm in the Eurotherm3235Trial. We stratified trial patients by International Mission for Prognosis and Analysis of Clinical Trials in [Traumatic Brain Injury] (IMPACT) extended model sum scores to determine where the balance of risks lay with the intervention. DESIGN: The Eurotherm3235Trial was a randomized controlled trial, with standardized and blinded outcome assessment...
March 8, 2017: Critical Care Medicine
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