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Feline heart

Jennifer L Bush, Sarah Nemanic, Jana Gordon, Gerd Bobe
Hyperthyroidism is the most common feline endocrinopathy; thyroid computed tomography (CT) may improve disease detection and methimazole dose selection. Objectives of this experimental pre-post with historical case-control study were to perform thyroid CT imaging in awake or mildly sedated hyperthyroid cats, compare thyroid gland CT appearance in euthyroid and hyperthyroid cats pre- and postmethimazole treatment, and determine whether thyroid size or attenuation correlate with methimazole dose needed for euthyroidism...
December 5, 2016: Veterinary Radiology & Ultrasound
M Beccaglia, S Alonge, C Trovo', G C Luvoni
Accurate prediction of delivery date in canine and feline allows a better management of parturition, reducing the loss of neonates. This review evaluates the most common methods adopted to accurately predict the day of delivery: determination of ovulation and hormonal assays, first appearance of embryonic/foetal structures using ultrasound or radiography, echographic measurement of extra-foetal and foetal structures, or evaluation of foetal flux and heart rate. Determination of ovulation and hormonal assays at the time of breeding and close to pregnancy term is widely used to predict parturition in dogs (Concannon et al...
September 2016: Reproduction in Domestic Animals, Zuchthygiene
K E Schober, S I Savino, V Yildiz
OBJECTIVES: To evaluate right ventricular (RV) wall thickness and chamber dimensions in cats with hypertrophic cardiomyopathy (HCM). ANIMALS: One hundred fifty-one healthy control cats and 200 cats with HCM. METHODS: Retrospective, observational, clinical cohort study. Two-dimensional echocardiograms from all cats were analyzed. Right atrial diameter, RV free wall thickness, and RV chamber diameter were quantified using multiple imaging views...
September 22, 2016: Journal of Veterinary Cardiology: the Official Journal of the European Society of Veterinary Cardiology
P G Blanco, R Vercellini, A Rube, R Rodríguez, D O Arias, C Gobello
The aim of this study was to describe resistance index (RI) and systolic/diastolic ratio (S/D ratio) of uterine and umbilical arteries in an experimental model of abnormal pregnancy in felids. On days 30 to 35 (32 ± 2.9) after mating, 20 domestic short-hair pregnant queens were randomly assigned to one of the following treatment groups: a treated group (TG; n = 8), which received 10 mg/kg of aglepristone subcutaneously twice, 24 hours apart, and a control nontreated group (CG; n = 12). M-mode and Doppler ultrasonographic evaluations were performed at the initiation of the treatment (Day 0) and then every other day during 8 days...
August 4, 2016: Theriogenology
J Häggström, Å O Andersson, T Falk, L Nilsfors, U OIsson, J G Kresken, K Höglund, M Rishniw, A Tidholm, I Ljungvall
BACKGROUND: Echocardiography is a cost-efficient method to screen cats for presence of heart disease. Current reference intervals for feline cardiac dimensions do not account for body weight (BW). OBJECTIVE: To study the effect of BW on heart rate (HR), aortic (Ao), left atrial (LA) and ventricular (LV) linear dimensions in cats, and to calculate 95% prediction intervals for these variables in normal adult pure-bred cats. ANIMALS: 19 866 pure-bred cats...
September 2016: Journal of Veterinary Internal Medicine
Y Kimura, S Karakama, A Hirakawa, S Tsuchiaka, M Kobayashi, N Machida
This study reports pathological and molecular features in 41 cases of feline restrictive cardiomyopathy (RCM). Grossly, there were patchy or diffuse areas of endocardial thickening affecting the left ventricle. The more common patchy endocardial lesions occurred as large trabecular or irregular broad bands of fibrous tissue bridging the left ventricular free wall and ventricular septum. Microscopically, regardless of the gross pattern, the thickened endocardium contained various numbers of stellate, spindle-shaped or elongated mesenchymal cells surrounded by fibrous connective tissue...
August 2016: Journal of Comparative Pathology
J DeLay
Autopsy of animals that die in the perianesthetic period allows identification of anesthetic and surgical complications as well as preexisting disease conditions that may have contributed to mortality. In most studies to date investigating perianesthetic mortality in animals, inclusion of autopsy data is very limited. This retrospective study evaluated autopsy findings in 221 cases of perianesthetic death submitted to a veterinary diagnostic laboratory from primary care and referral hospitals. Canine (n = 105; 48%) and feline (n = 90; 41%) cases predominated in the study, involving elective (71%) and emergency (19%) procedures...
September 2016: Veterinary Pathology
Jean-Sébastien Palerme, Ashley E Jones, Jessica L Ward, Nandhakumar Balakrishnan, Keith E Linder, Edward B Breitschwerdt, Bruce W Keene
INTRODUCTION: To describe the clinical presentation, clinicopathological abnormalities and outcomes of a series of cats diagnosed with infective endocarditis (IE) at two tertiary care referral institutions. ANIMALS: Thirteen client-owned cats presenting to the cardiology or emergency services of tertiary referral institutions with a diagnosis of endocarditis based on the modified Duke criteria. MATERIALS AND METHODS: Retrospective case series...
September 2016: Journal of Veterinary Cardiology: the Official Journal of the European Society of Veterinary Cardiology
Daniel Costa, Marta Leiva, Carolina Naranjo, José Ríos, Maria Teresa Peña
OBJECTIVE: To evaluate microbiological, histologic, and ultrastructural characteristics of short-term cryopreserved (STC) feline corneoscleral tissue (<1 year) and to compare it with long-term cryopreserved (LTC) tissue (>7 years). ANIMALS STUDIED: Twenty healthy feline globes were obtained from 2003 to 2013. PROCEDURE: After a decontamination protocol, globes were enucleated and stored at -20 °C in broad-spectrum antibiotics. Corneoscleral tissue was evaluated at different storage periods: <1 year (10 eyes) and >7 years (8 eyes)...
July 2016: Veterinary Ophthalmology
Kursten V Roderick, Amanda L Abelson, Lindsey Nielsen, Lori Lyn Price, Rebecca Quinn
OBJECTIVES: Congestive heart failure secondary to cardiomyopathy is a common manifestation of cardiac disease in cats, carrying a variable prognosis. The objective of this retrospective study is to evaluate the relationship between red blood cell distribution width (RDW) and survival time in feline patients with acquired heart disease with and without congestive heart failure (CHF). METHODS: Three hundred and forty-nine client-owned cats with echocardiograms and complete blood count, including RDW measurement, performed between March 2006 and December 2011, were included in the study...
May 25, 2016: Journal of Feline Medicine and Surgery
Julie A Kiland, Andrea M Voss, Gillian J McLellan
OBJECTIVE: To determine the effects of once-daily topical treatment with timolol maleate gel-forming solution (GFS) on intraocular pressure (IOP), pupil diameter (PD), and heart rate (HR) in normal cats and cats with feline primary congenital glaucoma (FCG). ANIMALS STUDIED AND PROCEDURES: A single drop of timolol maleate 0.5% GFS was administered topically to one randomly assigned eye of 18 adult cats (8 normal, 10 FCG) at 8 am for 8 days; the opposite eye served as the untreated control...
July 2016: Veterinary Ophthalmology
Feline F J A Ter Bruggen, Ismail Eralp, Leo Leliveld, Chris Jansen, Dirk L Stronks, Frank J P M Huygen
OBJECTIVE: During implantation of a neuromodulative system, high patient satisfaction is closely associated with the equilibrium between an effective analgesia and sedation regimen, and the possibility for the patient to be awake and cooperative during procedure. This study assessed the efficacy of the sedative dexmedetomidine to achieve this balance, with patient satisfaction as the primary outcome. METHODS: Ten patients undergoing implantation of a dorsal column and dorsal root ganglion stimulator received dexmedetomidine (1 mcg/kg over 10 minutes, followed by 0...
February 23, 2016: Pain Practice: the Official Journal of World Institute of Pain
Pamela B Andreatta, Suzanne L Dooley-Hash, Jessica J Klotz, Joe G Hauptman, Bea Biddinger, Joseph B House
OBJECTIVES: We evaluated the retention of pediatric and neonatal intubation performance abilities of clinicians trained on a simulated or live tissue model at 3 intervals after initial training to assess competency degradation related to either training modality or retention interval. METHODS: We implemented a quasi-experimental design with purposive sampling to assess performance differences between 171 subjects randomly assigned to 1 of 3 intervals after initial training: 6 weeks, 18 weeks, or 52 weeks...
February 2016: Pediatric Emergency Care
Carlo Guglielmini, Alessia Diana
Thoracic radiography is one of the most commonly employed diagnostic tools for the clinical evaluation of cats with suspected heart disease and is the standard diagnostic method in the confirmation of cardiogenic pulmonary edema. In the past, interpretation of feline radiographs focused on a description of the qualitative radiographic features of feline heart disease or the measurement of the cardiac silhouette in healthy cats and cats with different cardiovascular disorders. More recently, studies have begun to critically address the issue of the diagnostic accuracy of thoracic radiography in the diagnostic work-up of cats with heart disease...
December 2015: Journal of Veterinary Cardiology: the Official Journal of the European Society of Veterinary Cardiology
Barry J Maron, Philip R Fox
OBJECTIVES: To highlight similarities in hypertrophic cardiomyopathy (HCM) that are shared between humans and domestic cats. METHODS: Contemporary clinical and scientific findings were selected from the literature. Evidence is provided to support the concept that HCM in humans and felines are fundamentally the same disease. RESULTS: A number of remarkable similarities have been reported in certain spontaneously occurring myocardial disorders in domestic animals that closely resemble the clinical and phenotypic features of their corresponding diseases in humans...
December 2015: Journal of Veterinary Cardiology: the Official Journal of the European Society of Veterinary Cardiology
Daniel F Hogan, Philip R Fox, Kristin Jacob, Bruce Keene, Nancy J Laste, Steven Rosenthal, Kimberly Sederquist, Hsin-Yi Weng
OBJECTIVES: To determine if clopidogrel administration is associated with a reduced likelihood of recurrent cardiogenic arterial thromboembolism (CATE) in cats compared to aspirin administration. Secondary aims were to determine if clopidogrel administration had an effect on the composite endpoint of recurrent CATE and cardiac death and to identify adverse effects of chronic clopidogrel or aspirin therapy. ANIMALS: Seventy-five cats that survived a CATE event. METHODS: Multicenter, double-blind, randomized, positive-controlled study...
December 2015: Journal of Veterinary Cardiology: the Official Journal of the European Society of Veterinary Cardiology
L B Christiansen, C Prats, P Hyttel, J Koch
OBJECTIVES: Hypertrophic cardiomyopathy (HCM) is the most common heart disease in cats and shares clinical and pathological characteristics with human HCM. Little is known about the pathogenic mechanisms underlying development of spontaneous feline HCM. ANIMALS: The study population consisted of seven cats diagnosed with HCM and eight age-matched cats with no evidence of cardiac disease. METHODS: Fresh myocardial biopsies taken from the middle of the left ventricular posterior free wall were obtained and examined with transmission electron microscopy...
December 2015: Journal of Veterinary Cardiology: the Official Journal of the European Society of Veterinary Cardiology
Daniel F Hogan, Benjamin M Brainard
Cardiogenic embolism (CE) in the cat, which has also been referred to as arterial thromboembolism, feline arterial thromboembolism, and saddle thrombus has been identified clinically in cats for decades and is an important clinical development and cause of death in cats with underlying heart disease. While a better understanding of this condition has been developed over the decades it is extremely frustrating to clinicians that there have not been dramatic changes in prevention or outcome. Only recently has the first prospective thromboprophylactic study on CE in cats been completed...
December 2015: Journal of Veterinary Cardiology: the Official Journal of the European Society of Veterinary Cardiology
L Ferasin, T DeFrancesco
Acute heart failure in cats represents a complex clinical situation in feline practice and this review has been designed to focus on the description of acute heart failure in cats, the diagnostic approach and clinical management of acutely decompensated feline cardiac patients. The authors acknowledge the lack of scientific evidence regarding many treatments used for heart disease in cats, and hence their approach may differ from recommendations given by other cardiologists. Every individual cardiac cat is also different, and it is important that all treatments are carefully tailored to the individual...
December 2015: Journal of Veterinary Cardiology: the Official Journal of the European Society of Veterinary Cardiology
Sonya G Gordon, Etienne Côté
The natural progression of cardiomyopathy in cats can lead to congestive heart failure. This review enumerates commonly and uncommonly used medications that can be used for the long-term treatment of cats that have positively responded to initial management of acute heart failure. The advantages, drawbacks, and authors' preferred approach are presented for each medication.
December 2015: Journal of Veterinary Cardiology: the Official Journal of the European Society of Veterinary Cardiology
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