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Beuy Joob, Wiwanitkit Viroj
No abstract text is available yet for this article.
September 9, 2016: Turkish Neurosurgery
D S Nunes, H T Gonzaga, V S Ribeiro, J P Cunha-Júnior, J M Costa-Cruz
There is an increasing interest in improving neurocysticercosis (NCC) diagnosis through the search of new and alternative antigenic sources, as those obtained from heterologous antigens. The aim of this study was to obtain potential biomarkers for NCC diagnosis after gel filtration chromatography [gel filtration fraction (GFF)] from the total saline extract (SE) from Taenia saginata metacestodes, followed by protein identification and application in immunodiagnostic. SE and GFF proteic profiles were characterized in gel electrophoresis, and diagnostic performance was verified by testing 160 serum samples through enzyme-linked immunosorbent assay and immunoblotting...
October 17, 2016: Parasitology
Samuel Lapalme-Remis, Gregory D Cascino
PURPOSE OF REVIEW: This article discusses structural and functional neuroimaging findings in patients with seizures and epilepsy. The indications for neuroimaging in these patients and the potential diagnostic utility of these studies are presented. RECENT FINDINGS: Patients presenting with new seizures typically require urgent imaging to rule out a critical underlying cause. MRI is the structural neuroimaging procedure of choice in individuals with epilepsy. Specific epilepsy protocols should be considered to increase the diagnostic yield of neuroimaging in patients with structural lesions associated with focal or generalized seizures...
October 2016: Continuum: Lifelong Learning in Neurology
Prabhakar A, Mishra Vn, Tirkey Nk, Padia G, Bhagat D
No abstract text is available yet for this article.
January 2016: Journal of the Association of Physicians of India
Subhasis Pradhan, Upasana Kujur, R K Jha
No abstract text is available yet for this article.
January 2016: Journal of the Association of Physicians of India
Varun Gosain, Vasudeva Naik, Shetty Shivakumar
No abstract text is available yet for this article.
January 2016: Journal of the Association of Physicians of India
Piriyatharisini Thamilselvan, Krishna Raj Muthuraman, Jharna Mandal, Subash Chandra Parija
INTRODUCTION: Taenia solium is a common two-host parasitic cestode, residing in both humans (definitive) and pigs (intermediate). Invasion of this parasitic cyst into central nervous system leads to a condition known as neurocysticercosis (NCC). The World Health Organization (WHO) considers NCC as one of the "most neglected" tropical zoonotic diseases. The disease is presented with pleomorphic clinical manifestations, of which epilepsy is the most common. Diagnosis of NCC is carried out by serological tests and imaging methods...
July 2016: Tropical Parasitology
Theodore E Nash, Javier A Bustos, Hector H Garcia
Taenia solium (the pork tapeworm) is present in most developing countries, where it is a frequent cause of seizures and other neurological disease. Parasitic larvae invade the human brain, establish, and eventually resolve, leaving a calcified scar. While these lesions are common in endemic regions, and most of these are clinically silent, a proportion of individuals with calcified cysticerci develop seizures from these lesions, and 30-65% of these cases are associated with perilesional edema (PE), likely due to host inflammation...
October 3, 2016: Trends in Parasitology
Hong-Jiang Li, Hong-Xiu Han, Dong-Fu Feng
Reports describing a rapid increase in the cystic volume of anaplastic astrocytoma (AA) in a short time frame are rare. The present study reports the case of a 68-year-old male who was admitted to the No. 9 People's Hospital, Shanghai Jiaotong University School of Medicine (Shanghai, China), with a small cystic brain lesion and positive immunological testing for cysticercosis. Head magnetic resonance imaging (MRI) showed a cystic lesion, 6 mm in diameter, in the left frontal lobe. Neurocysticercosis was suspected and the patient was treated with a clinical trial of albendazole and steroids...
October 2016: Oncology Letters
M Vilhena, A G Fonseca, S Dias, J Marques DA Silva, J Torgal
Cysticercosis, a leading cause of acquired epilepsy in developing countries, has been controlled or eradicated in industrialized countries. This paradigm has recently been challenged, with human neurocysticercosis (NCC) being increasingly diagnosed in these countries. In order to assess the NCC burden in Portugal, a retrospective study on NCC hospitalizations (2006-2013) was conducted based on the national database on hospital morbidity: 357 hospitalized cases were detected. NCC was most frequent in the following age groups: 20-64 years (n = 197, 55·2%) >64 years (n = 111, 31·1%), and <20 years (n = 49, 13·7%)...
October 4, 2016: Epidemiology and Infection
Uffe Christian Braae, Pascal Magnussen, Wendy Harrison, Benedict Ndawi, Faustin Lekule, Maria Vang Johansen
Taenia solium is found throughout sub-Saharan Africa and co-endemic with schistosomiasis in many regions. Taenia solium leads to taeniosis and neurocysticercosis - the leading cause of preventable epilepsy globally. This study aimed to assess the effects of the National Schistosomiasis Control Programme on prevalence of taeniosis and porcine cysticercosis over a four year period in Tanzania. School-based mass drug administration (MDA) of praziquantel was carried out based on schistosomiasis endemicity. Four human and five porcine cross-sectional surveys were carried out from 2012 to 2015 in Mbozi and Mbeya district in Tanzania...
September 2016: Parasite Epidemiol Control
Nina M Christensen, Chiara Trevisan, Páll S Leifsson, Maria V Johansen
Neurocysticercosis caused by infection with Taenia solium is a significant cause of epilepsy and seizures in humans. The aim of this study was to assess the association between seizures and the deposition of collagen in brain tissue in pigs with T. solium neurocysticercosis. In total 78 brain tissue sections from seven pigs were examined histopathologically i.e. two pigs with epileptic seizures and T. solium cysts, four pigs without seizures but with cysts, and one non-infected control pig. Pigs with epileptic seizures had a larger amount of collagen in their brain tissue, showing as large fibrotic scars and moderate amount of collagen deposited around cysts, compared to pigs without seizures and the negative control pig...
September 15, 2016: Veterinary Parasitology
Robert H Gilman
No abstract text is available yet for this article.
September 28, 2016: Nature Reviews. Neurology
Innocent Lule Segamwenge, Ngalyuka Paul Kioko, Celia Mukulu, Ogunsina Jacob, Wanzira Humphrey, Josephine Augustinus
INTRODUCTION: Neurocysticercosis is a common cause of seizures in low resource countries. There is a paucity of data regarding the extent of this infection in Namibia. There are multiple causes of First-time seizure including electrolyte abnormalities, infections, trauma, drugs, alcohol and many times no apparent cause can be found. We sought to describe the burden of Neurocysticercosis among individuals with a first-time seizure in Namibia. METHODS: We recruited 221 patients with a First-time seizure who presented to the Intermediate Hospital Oshakati between August 2012 and March 2014...
2016: Pan African Medical Journal
Pedro Tadao Hamamoto Filho, Alexandre Todorovic Fabro, Marianna Vaz Rodrigues, Rodrigo Bazan, Luiz Carlos Vulcano, Germano Francisco Biondi, Marco Antônio Zanini
PURPOSE: Neurocysticercosis is a major public health concern. Although its eradication appears feasible, the disease remains endemic in developing countries and has emerged again in Europe and in the USA. Basic studies on neurocysticercosis are needed to better understand the pathophysiologic mechanisms and, consequently, to improve treatment perspectives. Much has been published on experimental parenchymal neurocysticercosis, but there are no experimental models of racemose neurocysticercosis...
September 9, 2016: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
David R Hansberry, Nitin Agarwal, Leroy R Sharer, Ira M Goldstein
CLINICAL HISTORY: Intradural, extramedullary cervical spinal involvement is an uncommon manifestation of neurocysticercosis. CASE REPORT: A case of a middle-aged man with neurocysticercosis in the intradural extramedullary cervical spine and brain who originally presented with bilateral paresthesias of his extremities, with a progressively unsteady gait. Magnetic resonance imaging revealed cystic enhancing lesions in the brain and cervical region of the spine, with the largest cyst extending from the posterior fossa through C2, causing spinal cord compression...
September 9, 2016: European Spine Journal
Sangeetha Yoganathan, Sniya Valsa Sudhakar, Maya Mary Thomas, Vikas Kapildeo Yadav
Japanese encephalitis (JE) is a mosquito borne encephalitis caused by Flavivirus. Neurocysticercosis (NCC) is a parasitic disease of the central nervous system caused by Taenia solium. In this report, we describe the clinical profile, imaging findings, and outcome of two children with JE and coexisting NCC. Eleven and thirteen-year-old boys from the same town of Jharkhand state were brought with history of fever, seizures, altered sensorium, and extrapyramidal symptoms. Dystonia, hypomimia, bradykinesia, and dyskinesia were observed...
April 2016: Journal of Pediatric Neurosciences
Anqi Xiao, Hanjiang Zeng, Jiahe Xiao, Xiaoke Zhang, Chao You
AIM: To investigate the imaging features of neurocysticercosis to provide clinicians with valuable information in the diagnosis and treatment. MATERIAL AND METHODS: 71 consecutive cases of neurocysticercosis diagnosed by CT and MRI in the duration from January 2009 to January 2014 in our institute were collected. Of all the cases, 57 patients met the recognized diagnostic criteria of neurocysticercosis. In this series, 55 cases were positive in ELISA examination, 3 cases were positive in cysticercosis IgG, and 11 cases were confirmed by surgery...
December 7, 2015: Turkish Neurosurgery
Naim Haddad, Gayane Melikyan, Hassan Al Hail, Ayman Al Jurdi, Faten Aqeel, Abdullah Elzafarany, Nour Abuhadra, Mujahed Laswi, Yasser Alsamman, Basim Uthman, Dirk Deleu, Boulenouar Mesraoua, Gonzalo Alarcon, Nabil Azar, Leopold Streletz, Ziyad Mahfoud
OBJECTIVE: Qatar is a small country on the Eastern coast of the Arabian Peninsula. Its population is a unique mixture of native citizens and immigrants. We aimed to describe the features of epilepsy in Qatar as such information is virtually lacking from the current literature. METHODS: We summarized information retrospectively collected from 468 patients with epilepsy seen through the national health system adult neurology clinic. RESULTS: Epilepsy was classified as focal in 65...
October 2016: Epilepsy & Behavior: E&B
Anqi Xiao, Jiahe Xiao, Xiaoke Zhang, Chao You
AIM: To investigate the indications and clinical value of the surgical therapy of neurocysticercosis (NCC). MATERIAL AND METHODS: We retrospectively reviewed all 10 patients with NCC treated surgically from January 2009 to January 2014 in our institute. The NCC types included parenchymal cysticerci in 6 cases, subarachnoid cysticerci in 3 and ventricular cysticerci in 1. RESULTS: All 10 patients underwent resection of cysticerci through craniotomy...
2016: Turkish Neurosurgery
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