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Neurocysticercosis

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https://www.readbyqxmd.com/read/28527268/-seroprevalence-and-risk-factors-of-cysticercosis-in-two-rural-communities-in-anzo%C3%A3-tegui-state-venezuela
#1
Manuel Toquero, Antonio Morocoima, Elizabeth Ferrer
INTRODUCTION: Cysticercosis is caused by Taenia solium cysticerci, which are located mainly in the central nervous system causing neurocysticercosis. In Venezuela, few epidemiological studies on this disease have been conducted. OBJECTIVE: To determine the seroprevalence and risk factors for cysticercosis in two rural communities in Anzoátegui state. MATERIAL AND METHODS: We conducted a survey to collect data on possible risk factors and signs and symptoms of the disease, and we took 182 samples in two communities, Boquerón and Punto Lindo...
April 1, 2017: Biomédica: Revista del Instituto Nacional de Salud
https://www.readbyqxmd.com/read/28527263/-racemose-neurocysticercosis-neuroimaging-guides-the-diagnosis
#2
Carlos Hugo Zapata, Sergio Alberto Vargas, Carlos Santiago Uribe
Neurocysticercosis is the leading cause of parasitosis of the central nervous system and acquired epilepsy in developing countries. The clinical manifestations of neurocysticercosis, especially its racemose variant, are pleomorphic and unspecific, characteristics that hinder the diagnosis and make it a challenge for the clinician.The objective of this report was to describe two cases of racemose neurocysticercosis in which neuroimaging led to the definitive diagnosis. The first case involved a patient with persistent headache and focal neurological signs...
April 1, 2017: Biomédica: Revista del Instituto Nacional de Salud
https://www.readbyqxmd.com/read/28526213/epidemiology-of-neurocysticercosis-and-epilepsy-is-everything-described
#3
REVIEW
Jose F Tellez-Zenteno, Lizbeth Hernandez-Ronquillo
In recent years clinical and epidemiological research on cysticercosis has gained significant interest in some countries, especially in Latin American countries and some countries in Asia and Africa. For many years it has been proposed that the higher prevalence of epilepsy seen in some regions such as Latin-America could be explained by parasitic infections, particularly neurocysticercosis (NCC). In this review we discussed selected epidemiological topics of the association of NCC and epilepsy, such as global distribution around the world, identification of NCC in developed countries, drug resistant epilepsy and NCC...
May 16, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28507972/bilateral-coracoid-avulsion-fractures-with-unilateral-anterior-instability-with-glenoid-bone-loss-use-of-avulsed-fragment-for-reconstruction-of-glenoid
#4
Prateek Kumar Gupta, Ashis Acharya, Amit Mourya
INTRODUCTION: Coracoid fractures are often missed since the fracture is not visualized in a routine anteroposterior view of the shoulder and special views are not ordered. Shoulder dislocation is common but it is rare to have a dislocation with a coracoid fracture. The purpose of this paper is to present the rare occurrence of bilateral coracoid fractures in a patient with unilateral anterior shoulder instability managed using the same fractured coracoid fragment by the latarjet procedure...
November 2016: Journal of Orthopaedic Case Reports
https://www.readbyqxmd.com/read/28506245/comparison-of-t24h-his-gst-t24h-and-gst-ts8b2-recombinant-antigens-in-western%C3%A2-blot-elisa-and-multiplex-bead-based-assay-for-diagnosis-of-neurocysticercosis
#5
Ana Hernández-González, John Noh, María Jesús Perteguer, Teresa Gárate, Sukwan Handali
BACKGROUND: Currently, the reference standard assay for the serodiagnosis of neurocysticercosis (NCC) is the lentil lectin-bound glycoproteins/enzyme-linked immunoelectrotransfer blot (LLGP-EITB). The main disadvantage of this technique is the complexity of obtaining and purifying the LLGP extract. This could be solved by replacement with highly specific recombinant antigens from Taenia solium. Based on previous studies, we selected and produced the recombinant Ts8B2 and T24H proteins and applied them to three diagnostic techniques: western blot (WB), enzyme-linked immunosorbent assay (ELISA) and the multiplex bead-based assay (MBA)...
May 15, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28489921/time-trend-of-neurocysticercosis-in-children-with-seizures-in-a-tertiary-hospital-of-western-nepal
#6
Kalipatnam Seshagiri Rao, Sudhir Adhikari, Eva Gauchan, Brijesh Sathian, Ganesh B K, Sahisnuta Basnet, Prabhat Kumar Tiwari, Namraj Bahadur, Rajnish Mishra
INTRODUCTION: Neurocysticercosis is a common cause of seizure disorders in children of Western Nepal. The clinical presentation is variable. The incidence varies depending on the food habits and ethnicity of the population. The present study was undertaken with the objective of studying the mode of presentation, radiological findings and to determine the recent trend of the disease in children of Western Nepal. METHODS: Records from the Department of Pediatrics, Manipal Teaching Hospital, Pokhara, Nepal of children aged 0-17 years admitted from 2003 to 2015 and with the discharge diagnosis of seizure and neurocysticercosis (NCC) were reviewed...
May 10, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28484552/isolated-lumbar-intradural-extra-medullary-spinal-cysticercosis-simulating-tarlov-cyst
#7
Sumit Bansal, Ashish Suri, Mehar Chand Sharma, Aanchal Kakkar
Spinal cysticercosis is a very uncommon manifestation of neurocysticercosis, which is caused by the larvae of Taenia solium. Here, we present a rare case of isolated lumbar intradural extramedullary neurocysticercosis, initially thought to be Tarlov cyst. A 40-year-old man, presented with low backache for 1-year with radiation of pain to right leg for 3 months. The patient was treated successfully with the surgical removal of the cyst, followed by medical treatment. Spinal neurocysticercosis should be considered in the differential diagnosis in high-risk populations, with new symptoms suggestive of a spinal mass lesion...
April 2017: Asian Journal of Neurosurgery
https://www.readbyqxmd.com/read/28484543/a-rare-case-of-recurrence-of-primary-spinal-neurocysticercosis-mimicking-an-arachnoid-cyst
#8
Anirban Pal, Chaitali Biswas, Tirtha R Ghosh, Pulak Deb
Neurocysticercosis (NCC) is a common parasitic infection of the central nervous system but isolated primary spinal NCC is of very rare occurrence. The authors report a case of 44-year-old male, a postoperative case of multiple spinal NCC lesion excision 2 years ago, who presented with cauda equina syndrome and magnetic resonance imaging revealed a lesion mimicking an arachnoid cyst in the D1-9 region of the spinal cord. On intraoperative surgical exposure multiple cysts were found and excised. The suspicion of recurrence of NCC was confirmed by histopathology...
April 2017: Asian Journal of Neurosurgery
https://www.readbyqxmd.com/read/28470474/decompensated-liver-disease-in-a-patient-with-neurocysticercosis
#9
Sarah Safadi, Aly M Mohamed, Barakat A Altamimi, Robert G Strickland, Denis M McCarthy
No abstract text is available yet for this article.
May 3, 2017: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/28468527/spinal-racemose-cysticercosis-case-report-and-review
#10
Hussam A Yacoub, Ira Goldstein, Mohammad El-Ghanem, Leroy Sharer, Nizar Souayah
Cysticercosis is a common helminthic infection worldwide, endemic in Central and South America, sub-Saharan Africa, and Southeast Asia. Neurocysticercosis typically involves brain parenchyma, subarachnoid space, and the ventricular system. Although the spinal cord is frequently involved in patients with parenchymal neurocysticercosis, isolated spinal involvement is rare, occurring in only 1-3% of patients. We report a case of racemose spinal neurocysticercosis with brain parenchyma involvement in a 49-year-old Mexican man, who presented with unsteady gait and bilateral arm numbness and weakness...
May 4, 2017: Hospital Practice (Minneapolis)
https://www.readbyqxmd.com/read/28467600/recent-advancements-and-new-perspectives-in-animal-models-for-neurocysticercosis-immunopathogenesis
#11
REVIEW
N Arora, S Tripathi, P Kumar, P Mondal, A Mishra, A Prasad
Neurocysticercosis (NCC), one of the most common parasitic diseases of the central nervous system, is caused by Taenia solium. This parasite involves two hosts, intermediate hosts (pig and human) and a definitive host (human), and has various stages in its complex life cycle (eggs, oncosphere, cysticerci and adult tapeworm). Hence, developing an animal model for T. solium that mimics its natural course of infection is quite challenging. We have reviewed here the animal models frequently used to study immunopathogenesis of cysticercosis and also discussed their usefulness for NCC studies...
May 3, 2017: Parasite Immunology
https://www.readbyqxmd.com/read/28462844/understanding-the-association-of-neurocysticercosis-and-mesial-temporal-lobe-epilepsy-and-its-impact-on-the-surgical-treatment-of-patients-with-drug-resistant-epilepsy
#12
REVIEW
Marino Muxfeldt Bianchin, Tonicarlo Rodrigues Velasco, Lauro Wichert-Ana, Antonio Carlos Dos Santos, Américo Ceiki Sakamoto
Mesial temporal lobe epilepsy associated with hippocampal sclerosis (MTLE-HS) is one of the most common types of focal epilepsies. This is an epileptic syndrome commonly associated with treatment-resistant seizures, being also the most prevalent form of drug-resistant epilepsy which is treated surgically in most epilepsy surgery centers. Neurocysticercosis (NCC) is one of the most common parasitic infections of the central nervous system, and one of the most common etiological agents of focal epilepsy, affecting millions of patients worldwide...
April 24, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28449318/screening-diagnosis-and-management-of-human-cysticercosis-and-t-solium-taeniasis-technical-recommendations-by-the-cohemi-project-study-group
#13
Lorenzo Zammarchi, Maurizio Bonati, Marianne Strohmeyer, Marco Albonico, Ana Requena-Méndez, Zeno Bisoffi, Alessandra Nicoletti, Hector H García, Alessandro Bartoloni
Neurocysticercosis, the central nervous system's localized form of cysticercosis, is considered to be the leading cause of epilepsy in the developing world. In Europe, the disease mainly imported and affects both immigrants and travellers. However, autochthonous cases of cysticercosis in low-endemic countries could also originate from T. solium carriers (migrants or travellers) who acquired taeniasis overseas. Management of cysticercosis is a challenge for European healthcare providers since they are often hardly aware of this infection and have little familiarity in managing this disease...
April 27, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28421303/erratum-to-geo-helminthiasis-among-migrants-in-sicily-a-possible-focus-for-re-emerging-neurocysticercosis-in-europe
#14
Ildebrando Patamia, Piermario Nicotra, Davide Amodeo, Loretta Giuliano, Calogero Edoardo Cicero, Alessandra Nicoletti
No abstract text is available yet for this article.
April 19, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28396789/neurocysticercosis-a-public-health-problem
#15
Elisa Carolina Jácome Sánchez, Edgar Patricio Correa Díaz, Braulio Martinez Burbano, María Angélica Ortiz Yépez, María Ariana García Castillo
Neurocysticercosis is a parasitic disease of the central nervous system that constitutes a public health problem in endemic regions. Here, we present a patient with epilepsy and cognitive impairment due to neurocysticercosis. A public health intervention could eradicate this disease in endemic regions such as Ecuador.
April 2017: Clinical Case Reports
https://www.readbyqxmd.com/read/28394979/-validity-of-three-methods-for-inmuno-diagnostic-of-neurocysticercosis-systematic-review-of-the-literature-with-meta-analysis-1960-2014
#16
Jaiberth Antonio Cardona-Arias, Yoneida Elena Carrasquilla-Agudelo, Deisy Cristina Restrepo-Posada
INTRODUCTION: The screening of neurocysticercosis is complex and immunological methods have varying validity. OBJECTIVE: To evaluate the validity of ELISA for antigen and antibody, and EITB for antibody in the screening of neurocysticercosis. METHODS: Meta-analysis of diagnostic tests with an ex-ante protocol implemented in five databases with 15 search strategies, ensuring reproducibility in the selection and extraction of information. Sensitivity, specificity, likelihood ratios (LR), diagnostic odds ratio and ROC curve were estimated in MetaDiSc, and predictive values, and Youden index were estimated in Epidat...
February 2017: Revista Chilena de Infectología: órgano Oficial de la Sociedad Chilena de Infectología
https://www.readbyqxmd.com/read/28380205/surgical-treatment-of-neurocysticercosis-retrospective-cohort-study-and-an-illustrative-case-report
#17
Aline Lariessy Campos Paiva, João Luiz Vitorino Araujo, Vinicius Ricieri Ferraz, Renan Maximilian Lovato, Charles Alfred Grander Pedrozo, Guilherme Brasileiro de Aguiar, José Carlos Esteves Veiga
CONTEXT AND OBJECTIVE: Neurocysticercosis is prevalent in developing countries and manifests with several neurological signs and symptoms that may be fatal. The cysts may be parenchymal or extraparenchymal and therefore several signs and symptoms may occur. Depending on their location, neurosurgical procedures may be required, sometimes as emergencies. The aim here was to review 10-year statistics on all surgical neurocysticercosis cases at a large public tertiary-level hospital. DESIGN AND SETTING: Retrospective cohort at a large public tertiary-level hospital...
March 2017: São Paulo Medical Journal, Revista Paulista de Medicina
https://www.readbyqxmd.com/read/28376856/the-causal-relationship-between-neurocysticercosis-infection-and-the-development-of-epilepsy-a-systematic-review
#18
REVIEW
Lucy B Gripper, Susan C Welburn
BACKGROUND: Neurocysticercosis (NCC) is a parasitic infection of the human central nervous system, the most common form of which involves infection of the brain parenchyma with the larval form of the Taenia solium tapeworm. A causal relationship between such an NCC infection and the development of epilepsy in infected individuals is acknowledged, in part supported by high levels of comorbidity in endemic countries worldwide. METHODS: This study undertook a systematic review and critical analysis of the NCC-epilepsy relationship with the primary objective of quantifying the risk of developing epilepsy following NCC infection...
April 5, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/28368546/natural-history-of-patients-with-perilesional-edema-around-taenia-solium-calcified-granulomas
#19
Theodore E Nash, JeanAnne M Ware, Siddhartha Mahanty
Background: The transient development of perilesional edema (PE) around ≥1 calcification (defined as 1 episode) occurs in about 50% of the patients with recurrent seizures in calcified neurocysticercosis (NCC). We determined the long-term clinical and radiological course of persons undergoing PE episodes. Methods: Twenty-one persons with NCC who experienced ≥1 PE episode were followed for a median of 10.6 years (range, 0.4-29.2 years). Clinical evaluations and magnetic resonance imaging (MRI) were performed at the time of suggestive symptoms and during routine follow-up...
April 1, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28344497/effect-of-nitazoxanide-on-albendazole-pharmacokinetics-in-cerebrospinal-fluid-and-plasma-in-rats
#20
María Isabel Ruiz-Olmedo, Iliana González-Hernández, Francisca Palomares-Alonso, Javier Franco-Pérez, María de Lourdes González F, Helgi Jung-Cook
Background: Although albendazole is the drug-of-choice for the treatment of neurocysticercosis, its efficacy is limited due to its low bioavailability. An alternative for optimizing pharmacological treatment is through drug combinations. In vitro studies have shown that nitazoxanide and tizoxanide (the active metabolite of nitazoxanide) exhibit cysticidal activity and that the combination of tizoxanide with albendazole sulfoxide (the active metabolite of albendazole) produced an additive effect. Objectives: (1) To assess the concentration profile of tizoxanide in plasma and in cerebrospinal fluid; and (2) to evaluate the influence of nitazoxanide on the pharmacokinetics of albendazole in plasma and in cerebrospinal fluid...
March 2017: Saudi Pharmaceutical Journal: SPJ: the Official Publication of the Saudi Pharmaceutical Society
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