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https://www.readbyqxmd.com/read/28651400/-mobile-internet-based-survey-of-current-status-of-hiv-test-and-related-factors-in-men-who-have-sex-with-men-in-college-students-in-china
#1
Y Y Jin, J Xu, Z Jiang, Z Y Wu
Objective: To assess the current status of HIV test during the past year and related factors in men who have sex with men (MSM) in college students in China. Methods: Based on a MSM website, a cross-sectional study was conducted in 500 MSM in college students aged 18-25 years, who were selected based on the estimated HIV detection rate of 50% in this population, by means of mobile phone questionnaire survey. χ(2) test and non-conditional multivariate logistic regression analysis were conducted to identify the factors related with HIV test, respectively...
May 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28651395/-analysis-of-dietary-pattern-and-diabetes-mellitus-influencing-factors-identified-by-classification-tree-model-in-adults-of-fujian
#2
F L Yu, Y Ye, Y S Yan
Objective: To find out the dietary patterns and explore the relationship between environmental factors (especially dietary patterns) and diabetes mellitus in the adults of Fujian. Methods: Multi-stage sampling method were used to survey residents aged ≥18 years by questionnaire, physical examination and laboratory detection in 10 disease surveillance points in Fujian. Factor analysis was used to identify the dietary patterns, while logistic regression model was applied to analyze relationship between dietary patterns and diabetes mellitus, and classification tree model was adopted to identify the influencing factors for diabetes mellitus...
May 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28651164/serum-levels-of-decabromodiphenyl-ether-bde-209-in-women-from-different-european-countries-and-possible-relationships-with-lifestyle-and-diet
#3
Martin van den Berg, Remko Houba, Heather A Leslie, Rocio F Canton, Cathrine Thomsen, Georg Becher, Mar Alvarez-Pedrerol, Jordi Sunyer Deu, Markus Steiner, Martie van Tongeren, Bert Brunekreef, Jacob de Boer
To determine possible effects of lifestyle, diet, housing and professional activities on differences in individual levels of decabromodiphenyl ether (BDE-209) in serum of women, 20 to 40years of age, in The Netherlands, the United Kingdom, Norway and Spain. BDE-209 was measured in serum of 145 female volunteers with no known occupational exposure from Norway, United Kingdom, The Netherlands and Spain. Blood levels of BDE-209 in a subgroup of 40 Dutch women were determined twice at a six months' interval. An extensive questionnaire was used to obtain detailed information about lifestyle factors that might contribute to BDE-209 exposure...
June 23, 2017: Environment International
https://www.readbyqxmd.com/read/28651148/aldo-keto-reductase-activity-after-diethylhexyl-phthalate-exposure-in-eutopic-and-ectopic-endometrial-cells
#4
La Yeon Kim, Mee Ran Kim, Jang Heub Kim, Hyun Hee Cho
OBJECTIVE: Endometriosis is a multifactorial gynaecological disease in reproductive-age women. Endometriotic tissue is characterized by high prostaglandin levels and progesterone resistance. Human aldo-keto reductases (AKRs) convert progesterone to a less potent metabolite and cause progesterone resistance. Therefore, in this study, we evaluated whether diethylhexyl phthalate (DEHP) alters AKR expression in human ectopic and eutopic endometrium. STUDY DESIGN: We used microarrays and western blotting to study the effects of DEHP, and checked the presence of AKR in endometriosis patients by enzyme-linked immunosorbent assay (ELISA)...
May 22, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28650979/expression-of-cerebral-serotonin-related-to-anxiety-like-behaviors-in-c57bl-6-offspring-induced-by-repeated-subcutaneous-prenatal-exposure-to-low-dose-lipopolysaccharide
#5
Pei-Tan Hsueh, Hsuan-Han Wang, Chiu-Lin Liu, Wei-Fen Ni, Ya-Lei Chen, Jong-Kang Liu
Prenatal exposure to lipopolysaccharide (LPS), which likely occurs due to infection or contact with environmental allergens during pregnancy, is a proposed risk factor that induces anxiety- and autism spectrum disorder-like behaviors in offspring. However, the molecular and behavioral changes in offspring after maternal immune activation have not been completely identified. We hypothesized that a subcutaneous injection of LPS in a pregnant mouse would induce changes in cerebral serotonin (5-HT) in parallel to the appearance of anxiety-like behaviors in the dam's offspring...
2017: PloS One
https://www.readbyqxmd.com/read/28650939/cd1d-restricted-natural-killer-t-cells-are-preserved-in-indian-long-term-nonprogressors
#6
Dharmendra Singh, Manisha Ghate, Sheela Godbole, Smita Kulkarni, Madhuri Thakar
BACKGROUND: Natural killer T (NKT) cells act as a bridge between innate and adaptive immune responses. Limited information is available regarding the role of NKT cells in the HIV disease progression especially HIV-1 C infection. METHODOLOGY: NKT cells were characterized for their frequency and the activation, aging, exhaustion status, and their proliferation ability in 32 long-term nonprogressors (LTNPs), 40 progressors, 18 patients before and after suppressive combination antiretroviral therapy (cART) along with 35 HIV-1-negative subjects using multicolor flow cytometry...
August 1, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/28650902/itpa-activity-in-adults-and-children-treated-with-or-without-azathioprine-relationship-between-tpmt-activity-thiopurine-metabolites-and-co-medications
#7
Boulieu Roselyne, Antony Citterio-Quentin, Mustapha Moulsma, Marie-Paule Gustin
BACKGROUND: The implication of inosine triphosphate pyrophosphatase (ITPA) on thiopurine drug response variability has been investigated but little data is available on its role on thiopurine metabolites. ITPA' ability to modify the thiopurine metabolite levels currently used to optimize azathioprine (AZA) therapy in relation to TPMT activity, the aim of this study is to investigate ITPA phenotype in a large population and to evaluate the relation between ITPA and TPMT activities and thiopurine metabolites...
June 22, 2017: Therapeutic Drug Monitoring
https://www.readbyqxmd.com/read/28650776/women-s-preferences-for-menstrual-bleeding-frequency-in-12-european-countries-the-inconvenience-due-to-women-s-monthly-bleeding-isy-survey
#8
Christian Fiala, Nathalie Chabbert-Buffet, Günther Häusler, Christian Jamin, Iñaki Lete, Paloma Lobo, Rossella E Nappi, Axelle Pintiaux
OBJECTIVES: Our aim was to assess the level of inconvenience associated with menstrual bleeding and determine how many women across 12 European countries would prefer a bleeding frequency of less than once a month and what would motivate their choice. METHODS: A 15-min quantitative online survey was conducted in two waves among 5728 women aged between 18 and 45 years, with an equal distribution of women using a combined hormonal contraceptive (CHC group, n = 2739) and women using a non-hormonal contraceptive or no contraceptive (non-HC group, n = 2989)...
June 26, 2017: European Journal of Contraception & Reproductive Health Care
https://www.readbyqxmd.com/read/28650754/structural-changes-in-the-lower-extremities-in-boys-aged-7-to-12-years-who-engage-in-moderate-physical-activityan-observational-longitudinal-study
#9
Gabriel Gijon-Nogueron, Salvador Diaz-Miguel, Eva Lopezosa-Reca, Jose Antonio Cervera-Marin
BACKGROUND: Physical activity in children may provide health benefits. We sought to consider the practice of soccer as a possible major factor in the development of the lower limb. The study is based on 3-year data for a group of children who practice this sport. METHODS: For 3 years we monitored 53 children who practiced soccer 3 times a week and had engaged in 2 years of continuous sports activity. Their mean ± SD age was 8.49 ± 2.01 years in the first year...
May 2017: Journal of the American Podiatric Medical Association
https://www.readbyqxmd.com/read/28650737/premenstrual-symptom-patterns-and-behavioral-risk-factors-in-young-women-a-cross-sectional-study
#10
Felicia A Quintana-Zinn, Brian W Whitcomb, Alayne G Ronnenberg, Carol Bigelow, Serena C Houghton, Elizabeth R Bertone-Johnson
BACKGROUND: Approximately 80% of reproductive age women experience physical or emotional symptoms before onset of menses. Of these women, ∼20% experience symptoms severe enough to interfere with social functioning and life activities, and meet clinical criteria for premenstrual syndrome (PMS). More than 100 different symptoms are associated with PMS. Symptom groupings tend to be stable within an individual, but vary distinctly between women. Potential differences in the etiology of symptoms suggest that PMS may have subtypes that represent distinct entities...
June 26, 2017: Journal of Women's Health
https://www.readbyqxmd.com/read/28650691/changes-in-cartilage-biomarker-levels-during-a-transcontinental-multistage-footrace-over-4486-km
#11
Annegret Mündermann, Christopher Klenk, Christian Billich, Corina Nüesch, Geert Pagenstert, Arno Schmidt-Trucksäss, Uwe Schütz
BACKGROUND: Cartilage turnover and load-induced tissue changes are frequently assessed by quantifying concentrations of cartilage biomarkers in serum. To date, information on the effects of ultramarathon running on articular cartilage is scarce. HYPOTHESIS: Serum concentrations of cartilage oligomeric matrix protein (COMP), matrix metalloproteinase (MMP)-1, MMP-3, MMP-9, COL2-3/4C long mono (C2C), procollagen type II C-terminal propeptide (CPII), and C2C:CPII will increase throughout a multistage ultramarathon...
June 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28650674/variation-in-actigraphy-estimated-rest-activity-patterns-by-demographic-factors
#12
Jonathan A Mitchell, Mirja Quante, Suneeta Godbole, Peter James, J Aaron Hipp, Catherine R Marinac, Sara Mariani, Elizabeth M Cespedes Feliciano, Karen Glanz, Francine Laden, Rui Wang, Jia Weng, Susan Redline, Jacqueline Kerr
Rest-activity patterns provide an indication of circadian rhythmicity in the free-living setting. We aimed to describe the distributions of rest-activity patterns in a sample of adults and children across demographic variables. A sample of adults (N = 590) and children (N = 58) wore an actigraph on their nondominant wrist for 7 days and nights. We generated rest-activity patterns from cosinor analysis (MESOR, acrophase and magnitude) and nonparametric circadian rhythm analysis (IS: interdaily stability; IV: intradaily variability; L5: least active 5-hour period; M10: most active 10-hour period; and RA: relative amplitude)...
June 26, 2017: Chronobiology International
https://www.readbyqxmd.com/read/28650582/synergistic-modulation-of-inflammatory-but-not-metabolic-effects-of-high-fat-feeding-by-ccr2-and-cx3cr1
#13
Hanrui Zhang, Christine C Hinkle, Sean M O'Neill, Jianting Shi, Jennifer Caughey, Emma Lynch, Gina Lynch, Mark Gerelus, Andrew S D Tsai, Rachana Shah, Jane F Ferguson, Rexford S Ahima, Muredach P Reilly
OBJECTIVE: The purpose of the study was to explore the impact of dual targeting of C-C motif chemokine receptor-2 (CCR2) and fractalkine receptor (CX3CR1) on the metabolic and inflammatory consequences of obesity induced by a high-fat diet (HFD). METHODS: C57BL/6J wild-type, Cx3cr1(-/-) , Ccr2(-/-) , and Cx3cr1(-/-) Ccr2(-/-) double-knockout male and female mice were fed a 45% HFD for up to 25 weeks starting at 12 weeks of age. RESULTS: All groups gained weight at a similar rate and developed a similar degree of adiposity, hyperglycemia, glucose intolerance, and impairment of insulin sensitivity in response to HFD...
June 26, 2017: Obesity
https://www.readbyqxmd.com/read/28650517/adaptive-change-in-chewing-related-brain-activity-while-wearing-a-palatal-plate-an-fmri-study
#14
Yuka Inamochi, Kenji Fueki, Nobuo Usui, Masato Taira, Noriyuki Wakabayashi
Prosthodontic treatment success depends on patients' ability to adapt to an altered oral environment containing removable prostheses. We investigated adaptive chewing-related brain activity changes in response to a new oral environment. Twenty-eight fully dentate subjects (mean age: 28.6 years) wore experimental denture-base palatal plates (3-mm thick), for 7 days. We measured food mixing ability and cycle time, and assessed brain activity by functional magnetic resonance imaging during chewing at pre-insertion (Day 0), and immediately (Day 1), 3 days (Day 3), and 7 days (Day 7) after insertion...
June 26, 2017: Journal of Oral Rehabilitation
https://www.readbyqxmd.com/read/28650451/inability-to-work-and-need-for-disability-pension-among-long-term-survivors-of-hematopoietic-stem-cell-transplantation
#15
A Tichelli, S Gerull, A Holbro, A Buser, G Nair, M Medinger, D Heim, J P Halter, J R Passweg
Return to work is critical goal following HSCT. However, late effects may impede return to normal activity after HSCT. In the case of inability to work, patients may need a work disability pension to ensure a reasonable livelihood. This study evaluated inability to work and need for disability pension among long-term survivors and analyzed possible determinants of need for social support. This retrospective, single-center study included all HSCT patients surviving ⩾5 years seen at the outpatient clinic between January 2013 and August 2015...
June 26, 2017: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/28650351/changes-in-health-and-fitness-in-firefighter-recruits-an-observational-cohort-study
#16
David J Cornell, Stacy L Gnacinski, Barbara B Meyer, Kyle T Ebersole
PURPOSE: To observe longitudinal changes in health and fitness among firefighter recruits. METHODS: Body composition, aerobic capacity, muscular power, muscular strength, and muscular endurance measures were longitudinally collected among 27 male firefighter recruits (mean ± SD, age = 29.9 ± 4.1 yrs; height = 179.8 ± 4.6 cm; body mass = 87.2 ± 9.7 kg) at the beginning (W1) and end (W14) of their firefighter training academy, as well as at the end of their probationary period (W38)...
June 22, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28650335/development-of-ad-like-symptoms-following-co-administration-of-alcl3-and-d-gal-in-rats-a-neurochemical-biochemical-and-behavioural-study
#17
Laraib Liaquat, Saara Ahmad, Sadia Sadir, Zehra Batool, Saima Khaliq, Saiqa Tabassum, Shaista Emad, Syeda Madiha, Sidrah Shahzad, Saida Haider
Alzheimer's disease (AD) is an age-related neurodegenerative disorder associated with neurochemical and neurobehavioural alterations. Aluminium (Al) is considered as a contributing factor in the etiology of several neurodegenerative disorders like AD. D-galactose (D-gal) is a physiological nutrient but over supply induces some neurochemical and biochemical changes that exacerbate natural aging process. In this study, we aimed to develop AD animal model by co-administration of Al and D-gal in rats. Male albino Wistar rats were intraperitoneally injected with AlCl3 and D-gal at a dose of 150mg/kg and 300mg/kg respectively for one week...
March 2017: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28650332/nepeta-rtanjensis-lamiaceae-a-plant-endemic-to-the-balkans-phenolic-composition-antioxidant-activity-and-in-vitro-antigenotoxic-effects-in-triiodothyronine-induced-dna-damage-in-human-lymphocytes
#18
Jasna Bošnjak-Neumüller, Milena Radaković, Ninoslav Djelić, Branka Vuković-Gačić, Zora Dajić Stevanović, Stoimir Kolarević, Danijela Mišić, Milan Stanković, Jelena Knežević-Vukčević, Biljana Spremo-Potparević, Zoran Stanimirović
The success of antioxidant therapy in hyperthyroidism implies that disease is mediated by oxidative stress, which is known as one of the causing agents of ageing, degenerative diseases, and cancer. The main objective of our study was to determine possible protective effects of methanolic extract of N. rtanjensis in triiodothyronine (T3)-induced DNA breaks of human lymphocytes under in vitro conditions, based upon plant antioxidant capacity related to its phytochemical profile, mainly its polyphenolic complex...
March 2017: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28650255/patient-navigation-for-traumatic-brain-injury-promotes-community-re-integration-and-reduces-re-hospitalizations
#19
Emily R Rosario, Laura Espinoza, Stephanie Kaplan, Sepehr Khonsari, Earl Thurndyke, Melissa Bustos, Kayla Vickers, Brittney Navarro, Bonnie Scudder
OBJECTIVE: To determine the effectiveness of a Navigation programme for patients with traumatic brain injury. DESIGN: Prospective programme evaluation. SETTING: Inpatient rehabilitation facility and community settings. PARTICIPANTS: Eighteen individuals who suffered a traumatic brain injury (TBI), were between the ages of 16-70 years, and had a Rancho Score greater than IV. INTERVENTION: Patient navigation programme focused on identifying and addressing barriers to positive outcomes, including coordination of care and facilitating communication among the family and healthcare providers, psychosocial support, caregiver support, adherence to treatment, education, community resources and financial issues...
June 26, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28650110/reproducibility-of-in-vivo-magnetic-resonance-imaging-t1-rho-and-t2-relaxation-time-measurements-of-hip-cartilage-at-3-0t-in-healthy-volunteers
#20
Angeline Nemeth, Lucy Di Marco, Florent Boutitie, Michael Sdika, Denis Grenier, Muriel Rabilloud, Olivier Beuf, Jean-Baptiste Pialat
PURPOSE: To assess the T1 ρ and T2 values in the hip cartilage of healthy volunteers and to evaluate the reproducibility of these measurements. MATERIALS AND METHODS: The right hip joint of 30 asymptomatic volunteers was explored with 3T magnetic resonance imaging (MRI). Quantitative 3D T1 ρ- and T2 -maps sequences were repeated twice with a 30-minute delay (immediate reproducibility). The same protocol was repeated 14 days later (short-term reproducibility). Immediate and short-term reproducibility were estimated using coefficients of variation and correlation concordance coefficients (CCC)...
June 26, 2017: Journal of Magnetic Resonance Imaging: JMRI
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