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https://www.readbyqxmd.com/read/27936458/predictors-of-functional-disability-with-focus-on-activities-of-daily-living-a-community-based-follow-up-study-in-older-adults-in-india
#1
Aarti Nagarkar, Yashoda Kashikar
BACKGROUND: Disability in activities of daily living is a growing concern among older populations all over the world. India has one of the rapidly ageing populations and predicted burden of functional disability is higher for Indian older adults as compared to other ageing Asian countries. METHODS: Total 1140 aged 60 years and over participated in a baseline study. 560 of them participated in the prospective cohort study conducted in the city of Pune, India. An interview and functional assessment using a questionnaire and Pune-FAAT tool was carried out in 2013-14...
December 2, 2016: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/27936422/social-network-types-among-older-korean-adults-associations-with-subjective-health
#2
Sung Yun Sohn, Won-Tak Joo, Woo Jung Kim, Se Joo Kim, Yoosik Youm, Hyeon Chang Kim, Yeong-Ran Park, Eun Lee
With population aging now a global phenomenon, the health of older adults is becoming an increasingly important issue. Because the Korean population is aging at an unprecedented rate, preparing for public health problems associated with old age is particularly salient in this country. As the physical and mental health of older adults is related to their social relationships, investigating the social networks of older adults and their relationship to health status is important for establishing public health policies...
December 1, 2016: Social Science & Medicine
https://www.readbyqxmd.com/read/27936361/the-relationship-between-drinking-pattern-social-capital-and-area-deprivation-findings-from-the-health-survey-for-england
#3
Linda Ng Fat, Shaun Scholes, Stephen Jivraj
OBJECTIVE: The purpose of this study was to establish the relationships between heavy episodic and drinking frequency with area-deprivation and social capital in England. METHOD: Using the Health Survey for England 2002-2006, a nationally representative crosssectional survey (N = 54,422), multilevel logistic regression models with individuals nested within primary sampling units were carried out, stratified by sex, on (a) drinkers versus nondrinkers, (b) heavy episodic drinking versus drinking less (on the heaviest drinking day), and (c) fewer than 2 drink-free days versus at least 2 drink-free days...
January 2017: Journal of Studies on Alcohol and Drugs
https://www.readbyqxmd.com/read/27936340/high-morning-blood-pressure-surge-is-associated-with-oxidative-stress-and-paraoxonase-1-activity-in-newly-diagnosed-hypertensive-patients
#4
Onur Kaypaklı, Mustafa Gür, Hazar Harbalıoğlu, Taner Şeker, Şahabettin Selek
BACKGROUND: Both oxidative stress and morning surge (MS) of blood pressure (BP) were found to be closely related with cardiovascular and cerebrovascular diseases. We investigated the association between MS of BP and oxidative stress in newly diagnosed hypertensive patients. METHODS: We prospectively included 237 newly diagnosed hypertensive patients in the present study (mean age: 51.6 ± 11.7 years). The patients were classified according to the extent of the sleep-through surge as follows: the top decile of sleep-through surge (>47...
December 9, 2016: Clinical and Experimental Hypertension: CHE
https://www.readbyqxmd.com/read/27936278/the-relationship-between-grammatical-development-and-disfluencies-in-preschool-children-who-stutter-and-those-who-recover
#5
Julia Hollister, Amanda Owen Van Horne, Patricia Zebrowski
Purpose: The dual diathesis stressor model indicates that a mismatch between a child's endogenous linguistic abilities and exogenous linguistic contexts is one factor that contributes to stuttering behavior. In the present study, we used a developmental framework to investigate if reducing the gap between endogenous and exogenous linguistics factors would result in less disfluency for typical children, children who recover from stuttering (CWS-R), and children who persist. Method: Children between 28 and 43 months of age participated in this study: 8 typical children, 5 CWS-R, and 8 children who persist...
December 9, 2016: American Journal of Speech-language Pathology
https://www.readbyqxmd.com/read/27936262/-a-mental-health-hygiene-experiment-the-case-of-les-pinceaux-d-or
#6
Hubert Wallot
Many research, notably that of Gene Cohen (2007), have shown positive impact of artistic activities for seniors. In 2006 in Quebec City, three professional painters have created a none lucrative organization called Les Pinceaux d'Or (The Golden Brushes). Its mission is to create a positive experience of painting learning in elderly needing persons. The organization operates in long-term health-care facilities or in low-income housings and day centers. It offers free painting courses to elderly persons referred by local community health centers or community organizations as seniors with psychosocial needs...
2016: Santé Mentale Au Québec
https://www.readbyqxmd.com/read/27936208/developmental-stage-muscle-and-genetic-type-modify-muscle-transcriptome-in-pigs-effects-on-gene-expression-and-regulatory-factors-involved-in-growth-and-metabolism
#7
Miriam Ayuso, Almudena Fernández, Yolanda Núñez, Rita Benítez, Beatriz Isabel, Ana I Fernández, Ana I Rey, Antonio González-Bulnes, Juan F Medrano, Ángela Cánovas, Clemente J López-Bote, Cristina Óvilo
Iberian pig production includes purebred (IB) and Duroc-crossbred (IBxDU) pigs, which show important differences in growth, fattening and tissue composition. This experiment was conducted to investigate the effects of genetic type and muscle (Longissimus dorsi (LD) vs Biceps femoris (BF)) on gene expression and transcriptional regulation at two developmental stages. Nine IB and 10 IBxDU piglets were slaughtered at birth, and seven IB and 10 IBxDU at four months of age (growing period). Carcass traits and LD intramuscular fat (IMF) content were measured...
2016: PloS One
https://www.readbyqxmd.com/read/27936162/discovery-of-a-novel-isothiazolonaphthoquinone-based-small-molecule-activator-of-foxo-nuclear-cytoplasmic-shuttling
#8
Bastien Cautain, Francisco Castillo, Loana Musso, Bibiana I Ferreira, Nuria de Pedro, Lorena Rodriguez Quesada, Susana Machado, Francisca Vicente, Sabrina Dallavalle, Wolfgang Link
FOXO factors are tumour suppressor proteins commonly inactivated in human tumours by posttranslational modifications. Furthermore, genetic variation within the FOXO3a gene is consistently associated with human longevity. Therefore, the pharmacological activation of FOXO proteins is considered as an attractive therapeutic approach to treat cancer and age-related diseases. In order to identify agents capable of activating FOXOs, we tested a collection of small chemical compounds using image-based high content screening technology...
2016: PloS One
https://www.readbyqxmd.com/read/27936149/increased-bone-mass-in-female-mice-lacking-mast-cell-chymase
#9
Thomas Lind, Ann-Marie Gustafson, Gabriela Calounova, Lijuan Hu, Annica Rasmusson, Kenneth B Jonsson, Sara Wernersson, Magnus Åbrink, Göran Andersson, Sune Larsson, Håkan Melhus, Gunnar Pejler
Here we addressed the potential impact of chymase, a mast-cell restricted protease, on mouse bone phenotype. We show that female mice lacking the chymase Mcpt4 acquired a persistent expansion of diaphyseal bone in comparison with wild type controls, reaching a 15% larger diaphyseal cross sectional area at 12 months of age. Mcpt4-/- mice also showed increased levels of a bone anabolic serum marker and higher periosteal bone formation rate. However, they were not protected from experimental osteoporosis, suggesting that chymase regulates normal bone homeostasis rather than the course of osteoporosis...
2016: PloS One
https://www.readbyqxmd.com/read/27936147/absence-of-association-between-behavior-problems-in-childhood-and-hypertension-in-midlife
#10
Sadiq M Saad, Gurch Randhawa, Dong Pang
BACKGROUND: It is known that behavior in childhood is associated with certain physical and mental health problems in midlife. However, there is limited evidence on the role of childhood behavior problems in the development of hypertension in adulthood. The present study aimed to examine whether behavior problems in childhood influenced the risk of hypertension in midlife in the United Kingdom 1958 birth cohort. METHODS: The 1958 British birth cohort comprised 17,638 individuals born in the first week of March 1958 in the United Kingdom...
2016: PloS One
https://www.readbyqxmd.com/read/27936145/diurnal-patterns-of-physical-activity-in-relation-to-activity-induced-energy-expenditure-in-52-to-83-years-old-adults
#11
Giulio Valenti, Alberto G Bonomi, Klaas R Westerterp
BACKGROUND: Ageing is associated with a declining physical activity level (PAL) and changes in the diurnal activity pattern. Changes in the activity pattern might help explaining the age-associated reduction of physical activity. OBJECTIVE: The aims were to investigate diurnal activity patterns within groups of older adults classified by PAL, to investigate diurnal activity patterns within age-groups and to investigate the association between the drop in activity and aerobic fitness...
2016: PloS One
https://www.readbyqxmd.com/read/27936139/epidemiological-and-virological-characteristics-of-influenza-in-chongqing-china-2011-2015
#12
Li Qi, Yu Xiong, Bangzhong Xiao, Wenge Tang, Hua Ling, Jiang Long, Dayong Xiao, Han Zhao, Sheng Ye, Shuang Chen, Zhen Yu, Qin Li
BACKGROUND: Chongqing is the largest municipality and located in Southwestern of China, with over 30 million registered inhabitants. There are few reports regarding the epidemiology of influenza in Chongqing. The objective of the paper is to explore the epidemiology of influenza in Chongqing, in order to provide scientific basis for prevention and control of influenza. METHODOLOGY /PRINCIPAL FINDINGS: From 2011 to 2015, we collected information on influenza-like illness (ILI) patients fulfilling the case definition, and took nasalpharyngeal or throat swabs specimens from ILI cases per week at the 7 sentinel hospitals...
2016: PloS One
https://www.readbyqxmd.com/read/27936094/lutein-attenuates-both-apoptosis-and-autophagy-upon-cobalt-ii-chloride-induced-hypoxia-in-rat-m%C3%A5-ller-cells
#13
Frederic K C Fung, Betty Y K Law, Amy C Y Lo
Retinal ischemia/reperfusion injury is a common feature of various retinal diseases such as glaucoma and diabetic retinopathy. Lutein, a potent anti-oxidant, is used to improve visual function in patients with age-related macular degeneration (AMD). Lutein attenuates apoptosis, oxidative stress and inflammation in animal models of acute retinal ischemia/hypoxia. Here, we further show that lutein improved Műller cell viability and enhanced cell survival upon hypoxia-induced cell death through regulation of intrinsic apoptotic pathway...
2016: PloS One
https://www.readbyqxmd.com/read/27936074/association-between-metabolic-syndrome-and-cognitive-impairment-after-acute-ischemic-stroke-a-cross-sectional-study-in-a-chinese-population
#14
Pan Li, Wei Quan, Da Lu, Yan Wang, Hui-Hong Zhang, Shuai Liu, Rong-Cai Jiang, Yu-Ying Zhou
BACKGROUND AND OBJECTIVES: Metabolic syndrome (MetS), a risk factor for many vascular conditions, is associated with vascular cognitive disorders. The objective of the present study was to explore the associations of MetS and its individual components with the risks of cognitive impairment and neurological dysfunction in patients after acute stroke. METHODS: This cross-sectional study enrolled 840 patients ranging in age from 53 to 89 years from the Tianjin area of North China...
2016: PloS One
https://www.readbyqxmd.com/read/27936024/estimation-of-physical-activity-energy-expenditure-during-free-living-from-wrist-accelerometry-in-uk-adults
#15
Tom White, Kate Westgate, Nicholas J Wareham, Soren Brage
BACKGROUND: Wrist-worn accelerometers are emerging as the most common instrument for measuring physical activity in large-scale epidemiological studies, though little is known about the relationship between wrist acceleration and physical activity energy expenditure (PAEE). METHODS: 1695 UK adults wore two devices simultaneously for six days; a combined sensor and a wrist accelerometer. The combined sensor measured heart rate and trunk acceleration, which was combined with a treadmill test to yield a signal of individually-calibrated PAEE...
2016: PloS One
https://www.readbyqxmd.com/read/27936002/the-significance-of-prolonged-and-saddleback-fever-in-hospitalised-adult-dengue
#16
Deborah Hl Ng, Joshua Gx Wong, Tun-Linn Thein, Yee-Sin Leo, David C Lye
Dengue fever is gaining importance in Singapore with an increase in the number of cases and mortality in recent years. Although prolonged and saddleback fever have been reported in dengue fever, there are no specific studies on their significance in dengue. This study aims to examine the prevalence of prolonged and saddleback fever in dengue as well as their associations with dengue severity. A total of 2843 polymerase-chain reaction (PCR) confirmed dengue patients admitted to Tan Tock Seng Hospital from 2004 to 2008 were included in the study...
2016: PloS One
https://www.readbyqxmd.com/read/27935988/effects-of-a-community-based-healthy-lifestyle-intervention-program-co-help-among-adults-with-prediabetes-in-a-developing-country-a-quasi-experimental-study
#17
Norliza Ibrahim, Foong Ming Moy, Intan Attikah Nur Awalludin, Zainudin Mohd Ali, Ikram Shah Ismail
BACKGROUND: The prevalence of type 2 diabetes among Malaysian adults has increased by more than two folds over the past two decades. Strategies to collaborate with the existing community partners may become a promising channel for wide-scale dissemination of diabetes prevention in the country. The objectives of this study were to determine the effects of community-based lifestyle interventions delivered to adults with prediabetes and their health-related quality of life as compared to the usual care group...
2016: PloS One
https://www.readbyqxmd.com/read/27935925/clinical-evaluation-of-fused-ankylosed-hip-with-severe-flexion-deformity-after-conversion-to-total-hip-arthroplasty
#18
S K Suwal, P Songming, L Gang, H Kui
INTRODUCTION: Fused or Ankylosed hip is late complication of chronic inflammatory disorder with progressive changes in and around articular as well as periarticular structures with alteration in bio-force line of body which later lead to severe flexion deformity of joint. This not only results decreased movements of hip, it's also increase pain around the hip, back and contralateral hip. METHODS: Retrospectively, all patients aged 18 years or older undergoing THA between June 2006 to June 2012 were reviewed with selection criteria...
April 2016: JNMA; Journal of the Nepal Medical Association
https://www.readbyqxmd.com/read/27935902/objectively-measured-physical-activity-and-sedentary-time-in-young-adults-born-preterm-the-ester-study
#19
Marjaana Tikanmäki, Tuija Tammelin, Nina Kaseva, Marika Sipola-Leppänen, Hanna-Maria Matinolli, Harto Hakonen, Ulf Ekelund, Johan G Eriksson, Marjo-Riitta Järvelin, Marja Vääräsmäki, Eero Kajantie
BackgroundYoung adults born preterm have higher levels of cardiometabolic risk factors and they report less physical activity than their peers born at term. Physical activity provides important cardiometabolic health benefits. We hypothesized that objectively measured physical activity levels are lower and time spent sedentary is higher among preterm-born individuals compared to controls.MethodsWe studied unimpaired participants of the ESTER birth cohort study at age 23.3 years (SD: 1.2): 60 born early preterm (<34 weeks), 108 late preterm (34-36 weeks), and 178 at term (controls)...
December 9, 2016: Pediatric Research
https://www.readbyqxmd.com/read/27935850/physical-activity-start-at-a-younger-age
#20
Joav Merrick
No abstract text is available yet for this article.
December 9, 2016: International Journal of Adolescent Medicine and Health
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