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https://www.readbyqxmd.com/read/29850429/advanced-endografting-techniques-snorkels-chimneys-periscopes-fenestrations-and-branched-endografts
#1
REVIEW
Kartik Kansagra, Joseph Kang, Matthew-Czar Taon, Suvranu Ganguli, Ripal Gandhi, George Vatakencherry, Cuong Lam
The anatomy of aortic aneurysms from the proximal neck to the access vessels may create technical challenges for endovascular repair. Upwards of 30% of patients with abdominal aortic aneurysms (AAA) have unsuitable proximal neck morphology for endovascular repair. Anatomies considered unsuitable for conventional infrarenal stent grafting include short or absent necks, angulated necks, conical necks, or large necks exceeding size availability for current stent grafts. A number of advanced endovascular techniques and devices have been developed to circumvent these challenges, each with unique advantages and disadvantages...
April 2018: Cardiovascular Diagnosis and Therapy
https://www.readbyqxmd.com/read/29770249/snorkel-rapid-training-data-creation-with-weak-supervision
#2
Alexander Ratner, Stephen H Bach, Henry Ehrenberg, Jason Fries, Sen Wu, Christopher Ré
Labeling training data is increasingly the largest bottleneck in deploying machine learning systems. We present Snorkel, a first-of-its-kind system that enables users to train state-of- the-art models without hand labeling any training data. Instead, users write labeling functions that express arbitrary heuristics, which can have unknown accuracies and correlations. Snorkel denoises their outputs without access to ground truth by incorporating the first end-to-end implementation of our recently proposed machine learning paradigm, data programming...
November 2017: Proceedings of the VLDB Endowment
https://www.readbyqxmd.com/read/29701345/emergency-nightmares-rupture-of-type-iii-thoracoabdominal-aneurysm
#3
Marina Dias-Neto, José Fernando Ramos, João Rocha Neves, Pedro Almeida, Augusto Rocha E Silva, José Fernando Teixeira
Introduction The rupture of thoracoabdominal aneurysms (rTAA) represents one of the major challenges to the vascular surgeon. Recent developments in the endovascular armamentarium and the high mortality from open surgery make endovascular treatment an attractive option. Devices to be used in an emergency environment should be "off-the-shelf" and include, among others, EVAR snorkel/chimney and branched endoprosthesis (T-branch, Cook®). METHODS: We describe the case of a 70-year-old patient who was admitted to the emergency room due continuous low back pain with 3 days of evolution...
July 2017: Revista Portuguesa de Cirurgia Cardio-torácica e Vascular
https://www.readbyqxmd.com/read/29680548/mapping-of-the-corals-around-hendorabi-island-persian-gulf-using-worldview-2-standard-imagery-coupled-with-field-observations
#4
Keivan Kabiri, Hamid Rezai, Masoud Moradi
High spatial resolution WorldView-2 (WV2) satellite imagery coupled with field observations have been utilized for mapping the coral reefs around Hendorabi Island in the northern Persian Gulf. In doing so, three standard multispectral bands (red, green, and blue) were selected to produce a classified map for benthic habitats. The in-situ observations were included photo-transects taken by snorkeling in water surface and manta tow technique. The satellite image has been classified using support vector machine (SVM) classifier by considering the information obtained from field measurements as both training and control points data...
April 2018: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/29463078/current-endovascular-management-of-complex-pararenal-aneurysms
#5
Ashley J Williamson, Trissa Babrowski
INTRODUCTION: Endovascular approach to abdominal aortic aneurysm has increased in frequency over the last decade and is preferred by many practitioners and patients alike. However, its role in "complex" aneurysms with challenging anatomy, short neck length, or borderline landing zone for grafts is less well understood. Additionally, the endovascular role in complex urgent or emergent repairs has not been adequately studied. Several techniques have been developed in order to address these concerns and further the endovascular approach...
June 2018: Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/29433410/snorkel-technique-for-inferior-mesenteric-artery-during-endovascular-repair-of-abdominal-aortic-aneurysm
#6
Serkan Ertugay, Ahmet Daylan, Halil Bozkaya, Emrah Oğuz, Anıl Apaydın, Mustafa Parıldar, Hakan Posacıoğlu
PURPOSE: The snorkel technique is commonly used to preserve renal arteries in juxta renal aneurysm during endovascular repair. Herein, we present a patient who underwent bifurcated endograft implantation with snorkel technique for inferior mesenteric artery (IMA) in order to preserve the major source of bowel circulation. CASE REPORT: A 69-year-old male patient was diagnosed with abdominal aortic aneurysm. His history revealed that he had bowel resection due to a car accident 30 years ago...
April 2018: Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/29421415/clinical-outcomes-of-total-endovascular-aneurysm-repair-for-aortic-aneurysms-involving-the-proximal-anastomotic-aneurysm-following-initial-open-repair-for-infrarenal-abdominal-aortic-aneurysm
#7
Takeshi Baba, Takao Ohki, Yuji Kanaoka, Koji Maeda, Naoki Toya, Hiroki Ohta, Soichiro Fukushima, Masayuki Hara
BACKGROUND: To evaluate initial and midterm clinical outcomes of aortic aneurysms involving the proximal anastomotic aneurysm (AAPAAs) following initial open repair for infrarenal abdominal aortic aneurysm. METHODS: Between July 2006 and August 2015, 24 patients underwent elective endovascular repair for the treatment of AAPAAs at our institution. AAPAA classification has been categorized as 3 types. Type I AAPAA is the most extensive, extending from the descending aorta to the prior proximal anastomosis as similar to Crawford type II or III thoracoabdominal aortic aneurysm...
February 6, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/29196683/preferential-selection-of-arginine-at-the-lipid-water-interface-of-trpv1-during-vertebrate-evolution-correlates-with-its-snorkeling-behaviour-and-cholesterol-interaction
#8
Somdatta Saha, Arijit Ghosh, Nikhil Tiwari, Ashutosh Kumar, Abhishek Kumar, Chandan Goswami
TRPV1 is a thermo-sensitive ion channel involved in neurosensory and other physiological functions. The trans-membrane helices of TRPV1 undergo quick and complex conformational changes governed by thermodynamic parameters and membrane components leading to channel opening. However, the molecular mechanisms underlying such events are poorly understood. Here we analysed the molecular evolution of TRPV1 at the lipid-water-interface region (LWI), typically defined as a layer of 6 Å thickness on each side of the membrane with less availability of free water...
December 1, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29186227/-snorkelling-vs-diving-in-mixed-micelles-probed-by-means-of-a-molecular-bathymeter
#9
Gemma M Rodriguez-Muñiz, Miguel Gomez-Mendoza, Edurne Nuin, Inmaculada Andreu, M Luisa Marin, Miguel A Miranda
A photoactive bathymeter based on a carboxylic acid moiety covalently linked to a signalling methoxynaphthalene (MNP) fluorophore has been designed to prove the concept of "snorkelling" vs. "diving" in mixed micelles (MM). The carboxylic acid "floats" on the MM surface, while the MNP unit sinks deep in MM. The rate constants of MNP fluorescence quenching by iodide, which remains basically in water, consistently decrease with increasing spacer length, revealing different regions...
December 13, 2017: Organic & Biomolecular Chemistry
https://www.readbyqxmd.com/read/29153534/configuration-affects-parallel-stent-grafting-results
#10
Adam Tanious, Mathew Wooster, Paul A Armstrong, Bruce Zwiebel, Shane Grundy, Martin R Back, Murray L Shames
OBJECTIVE: A number of adjunctive "off-the-shelf" procedures have been described to treat complex aortic diseases. Our goal was to evaluate parallel stent graft configurations and to determine an optimal formula for these procedures. METHODS: This is a retrospective review of all patients at a single medical center treated with parallel stent grafts from January 2010 to September 2015. Outcomes were evaluated on the basis of parallel graft orientation, type, and main body device...
May 2018: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/29125878/insight-into-the-interactions-residue-snorkeling-and-membrane-disordering-potency-of-a-single-antimicrobial-peptide-into-different-lipid-bilayers
#11
Majid Jafari, Faramarz Mehrnejad, Farahnoosh Doustdar
Pardaxin, with a bend-helix-bend-helix structure, is a membrane-active antimicrobial peptide that its membrane activity depends on the lipid bilayer composition. Herein, all-atom molecular dynamics (MD) simulations were performed to provide further molecular insight into the interactions, structural dynamics, orientation behavior, and cationic residues snorkeling of pardaxin in the DMPC, DPPC, POPC, POPG, POPG/POPE (3:1), and POPG/POPE (1:3) lipid bilayers. The results showed that the C-terminal helix of the peptide was maintained in all six types of the model-bilayers and pardaxin was tilted into the DMPC, DPPC, and POPG/POPE mixed bilayers more than the POPC and POPG bilayers...
2017: PloS One
https://www.readbyqxmd.com/read/29096975/plastic-debris-collars-an-underreported-stressor-in-tropical-reef-fishes
#12
Joséde Anchieta C C Nunes, Cláudio L S Sampaio, Francisco Barros, Antoine O H C Leduc
Plastic debris collar wrappings (PDCW) are involved in the frequent entanglement of several groups of marine animals. In fishes, however aside from 'ghost fishing', PDCW events are rarely documented, and no record of this occurrence exists in tropical reef fishes. Here, we present records for four species afflicted by plastic debris collars. Observations occurred during snorkeling, and included the silver mojarra Eucinostomus argenteus, Atlantic thread herring Ophistonema oglinum, tomtate grunt Haemulon aurolineatum and gray parrotfish Sparisoma axillare...
October 30, 2017: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/29020640/bridging-spatially-segregated-redox-zones-with-a-microbial-electrochemical-snorkel-triggers-biogeochemical-cycles-in-oil-contaminated-river-tyne-uk-sediments
#13
Carolina Cruz Viggi, Bruna Matturro, Emanuela Frascadore, Susanna Insogna, Alessio Mezzi, Saulius Kaciulis, Angela Sherry, Obioma K Mejeha, Ian M Head, Eleni Vaiopoulou, Korneel Rabaey, Simona Rossetti, Federico Aulenta
Marine sediments represent an important sink for a number of anthropogenic organic contaminants, including petroleum hydrocarbons following an accidental oil spill. Degradation of these compounds largely depends on the activity of sedimentary microbial communities linked to biogeochemical cycles, in which abundant elements such as iron and sulfur are shuttled between their oxidized and reduced forms. Here we show that introduction of a small electrically conductive graphite rod ("the electrochemical snorkel") into an oil-contaminated River Tyne (UK) sediment, so as to create an electrochemical connection between the anoxic contaminated sediment and the oxygenated overlying water, has a large impact on the rate of metabolic reactions taking place in the bulk sediment...
December 15, 2017: Water Research
https://www.readbyqxmd.com/read/28990466/task-dependent-cold-stress-during-expeditions-in-antarctic-environments
#14
Drew M Morris, June J Pilcher, Robert B Powell
This study seeks to understand the degree of body cooling, cold perception and physical discomfort during Antarctic tour excursions. Eight experienced expedition leaders across three Antarctic cruise voyages were monitored during occupational tasks: kayaking, snorkelling and zodiac outings. Subjective cold perception and discomfort were recorded using a thermal comfort assessment and skin temperature was recorded using a portable data logger. Indoor cabin temperature and outdoor temperature with wind velocity were used as measures of environmental stress...
2017: International Journal of Circumpolar Health
https://www.readbyqxmd.com/read/28918189/effects-of-temperature-and-peg-grafting-density-on-the-translocation-of-pegylated-nanoparticles-across-asymmetric-lipid-membrane
#15
Zuoheng Zhang, Xubo Lin, Ning Gu
Plasma membrane internalization of nanoparticles (NPs) is important for their biomedical applications such as drug-delivery carriers. On one hand, in order to improve their half-life in circulation, PEGylation has been widely used. However, it may hinder the NPs' membrane internalization ability. On the other hand, higher temperature could enhance the membrane permeability and may affect the NPs' ability to enter into or exit from cells. To make full use of their advantages, we systematically investigated the effects of temperature and PEG density on the translocation of PEGylated nanoparticles across the plasma asymmetric membrane of eukaryotic cells, using near-atom level coarse-grained molecular dynamics simulations...
December 1, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/28873449/benthic-community-structure-on-coral-reefs-exposed-to-intensive-recreational-snorkeling
#16
Bobbie Renfro, Nanette E Chadwick
Chronic anthropogenic disturbances on coral reefs in the form of overfishing and pollution can shift benthic community composition away from stony corals and toward macroalgae. The use of reefs for recreational snorkeling and diving potentially can lead to similar ecological impacts if not well-managed, but impacts of snorkeling on benthic organisms are not well understood. We quantified variation in benthic community structure along a gradient of snorkeling frequency in an intensively-visited portion of the Mesoamerican Barrier Reef...
2017: PloS One
https://www.readbyqxmd.com/read/28774222/transradial-delivery-of-a-renal-snorkel-during-complex-endovascular-aortic-aneurysm-repair
#17
Jordan R Stern, Sharif H Ellozy
Transradial access has been described in a variety of clinical contexts but has been rarely utilized for visceral artery interventions and during complex endovascular aortic aneurysm repair (EVAR) when upper extremity access is required. This is usually accomplished via brachial artery access, and although brachial access is generally safe and effective, radial access may offer some benefits with regard to patient comfort and potential complications. Here we report a case of successful delivery of a renal snorkel via a radial artery approach during EVAR...
October 2017: Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/28739454/parallel-grafts-used-in-combination-with-physician-modified-fenestrated-stent-grafts-for-complex-aortic-aneurysms-in-high-risk-patients-with-hostile-anatomies
#18
Joseph Touma, Dorian Verscheure, Marek Majewski, Pascal Desgranges, Frederic Cochennec
OBJECTIVE: To evaluate the feasibility and early outcomes of complex aortic aneurysm repair in high risk patients with hostile anatomies using both parallel stents and physician-modified stent-graft (PMSG) techniques to address the renovisceral arteries METHODS: Consecutive patients with complex suprarenal (SRA) and thoracoabdominal aortic aneurysms (TAAA) undergoing endovascular repair using combined parallel stents technique and PMSG between September 2013 and November 2015 were evaluated...
July 21, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28700927/charged-antimicrobial-peptides-can-translocate-across-membranes-without-forming-channel-like-pores
#19
Jakob P Ulmschneider
How can highly charged, cationic antimicrobial peptides (AMPs) translocate across hydrophobic lipid bilayers despite the prohibitive energetic penalty to do so? A common explanation has been the formation of peptide-lined channels. However, for most AMPs, no structures of membrane pores have been found despite clear evidence of membrane leakage and antimicrobial activity. The study here suggests an alternative and simple reason: for the AMP PGLa from Xenopus laevis (charge +5), such pores are not needed to explain both leakage and peptide translocation...
July 11, 2017: Biophysical Journal
https://www.readbyqxmd.com/read/28689952/a-novel-off-the-shelf-technique-for-endovascular-repair-of-type-iii-and-iv-thoracoabdominal-aortic-aneurysms-using-the-gore-excluder-and-viabahn-branches
#20
Mathew Wooster, Adam Tanious, R Wesley Jones, Paul Armstrong, Murray Shames
BACKGROUND: The aim of this study is to describe the use of a novel off-the-shelf technique to repair type III and type IV thoracoabdominal aortic aneurysms (TAAAs) in the absence of available prefabricated branched devices. METHODS: All patients undergoing endovascular repair of type III and IV TAAAs using this technique were included from a prospectively maintained registry at a regional aortic referral center. The proximal bifurcated Gore C3 Excluder device is positioned in the descending thoracic aorta with the contralateral gate 2-3 cm above the celiac artery...
January 2018: Annals of Vascular Surgery
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