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https://www.readbyqxmd.com/read/28544519/the-effect-of-helium-oxygen-assisted-mechanical-ventilation-on-chronic-obstructive-pulmonary-disease-exacerbation-a-systemic-review-and-meta-analysis
#1
Xu Wu, Chuan Shao, Liang Zhang, Jinjing Tu, Hui Xu, Zhihui Lin, Shuguang Xu, Biyun Yu, Yaodong Tang, Shanqun Li
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is often accompanied by acute exacerbations. Patients of COPD exacerbation suffering from respiratory failure often need the support of mechanical ventilation. Helium-oxygen can be used to reduce airway resistance during mechanical ventilation. The aim of this study is to evaluate the effect of helium-oxygen-assisted mechanical ventilation on COPD exacerbation through a meta-analysis. METHODS: A comprehensive literature search through databases of Pub Med (1966∼2016), Ovid MEDLINE (1965∼2016), Cochrane EBM (1991∼2016), EMBASE (1974∼2016) and Ovid MEDLINE was performed to identify associated studies...
May 24, 2017: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/28544068/interstitial-fluid-pressure-a-novel-biomarker-to-monitor-photo-induced-drug-uptake-in-tumor-and-normal-tissues
#2
Sabrina Cavin, Xingyu Wang, Matthieu Zellweger, Michel Gonzalez, Michaël Bensimon, Georges Wagnières, Thorsten Krueger, Hans-Beat Ris, Fabrizio Gronchi, Jean Y Perentes
BACKGROUND: Low-dose photodynamic therapy PDT (photoinduction) can modulate tumor vessels and enhance the uptake of liposomal cisplatin (Lipoplatin®) in pleural malignancies. However, the photo-induction conditions must be tightly controlled as overtreatment shuts down tumor vessels and enhances normal tissue drug uptake. MATERIAL AND METHODS: In a pleural sarcoma and adenocarcinoma rat model (n = 12/group), we applied photoinduction (0.0625 mg/kg Visudyne®, 10 J/cm(2) ) followed by intravenous Lipoplatin® (5 mg/kg) administration...
May 22, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/28543722/a-comparison-of-optimization-algorithms-for-localized-in-vivo-b0-shimming
#3
Sahar Nassirpour, Paul Chang, Ariane Fillmer, Anke Henning
PURPOSE: To compare several different optimization algorithms currently used for localized in vivo B0 shimming, and to introduce a novel, fast, and robust constrained regularized algorithm (ConsTru) for this purpose. METHODS: Ten different optimization algorithms (including samples from both generic and dedicated least-squares solvers, and a novel constrained regularized inversion method) were implemented and compared for shimming in five different shimming volumes on 66 in vivo data sets from both 7 T and 9...
May 22, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28543615/improved-image-quality-and-reduced-power-deposition-in-the-spine-at-3-t-using-extremely-high-permittivity-materials
#4
Kirsten Koolstra, Peter Börnert, Wyger Brink, Andrew Webb
PURPOSE: To explore the effect of using extremely high permittivity (εr ∼1,000) materials on image quality and power requirements of spine imaging at 3 T. THEORY AND METHODS: A linear array of high permittivity dielectric blocks made of lead zirconate titanate (PZT) was designed and characterized by electromagnetic simulations and experiments. Their effect on the transmit efficiency, receive sensitivity, power deposition, and diagnostic image quality was analyzed in vivo in 10 healthy volunteers...
May 22, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28543587/optical-mapping-of-nonmelanoma-skin-cancers-a-pilot-clinical-study
#5
Anna N Yaroslavsky, Xin Feng, Victor A Neel
BACKGROUND AND OBJECTIVE: Nonmelanoma skin cancer (NMSC) is the most common human cancer. Because these tumors often affect the face, there is a strong need for both accurate removal of these neoplasms to prevent recurrence and maximal tissue preservation to prevent cosmetic or functional deformity. Polarization-enhanced reflectance and fluorescence imaging (PERFI) is a new bedside method that uses fluorescent chromophores to image NMSC. While the feasibility of the technique has been successfully demonstrated in ex vivo studies, this is the first pilot study to extend the use of PERFI to in vivo intraoperative imaging of NMSC...
May 23, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/28543430/planet-an-ellipse-fitting-approach-for-simultaneous-t1-and-t2-mapping-using-phase-cycled-balanced-steady-state-free-precession
#6
Yulia Shcherbakova, Cornelis A T van den Berg, Chrit T W Moonen, Lambertus W Bartels
PURPOSE: To demonstrate the feasibility of a novel, ellipse fitting approach, named PLANET, for simultaneous estimation of relaxation times T1 and T2 from a single 3D phase-cycled balanced steady-state free precession (bSSFP) sequence. METHODS: A method is presented in which the elliptical signal model is used to describe the phase-cycled bSSFP steady-state signal. The fitting of the model to the acquired data is reformulated into a linear convex problem, which is solved directly by a linear least squares method, specific to ellipses...
May 22, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28543331/integration-of-optical-applicator-with-balloon-catheter-for-photothermal-treatment-of-biliary-stricture
#7
Jinoh Bak, Jieun Hwang, Suhyun Park, Hyun W Kang
BACKGROUND AND OBJECTIVE: Bile duct stricture is an uncommon disease in gastroenterology resulting from postoperative trauma. In spite of non-surgical treatments, clinical outcomes for the biliary strictures still encounter high restenosis and stent migration. The objective of the current study was to investigate the feasible application of a balloon catheter-integrated diffing applicator to thermally treat the bile duct stricture. MATERIALS AND METHODS: 400-μm optical fibers were micro-machined and then integrated with an inflatable balloon catheter...
May 25, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/28541424/a-new-in-vitro-bioassay-system-for-the-discovery-and-quantitative-evaluation-of-mosquito-repellents
#8
Abbas Ali, Charles L Cantrell, Ikhlas A Khan
Mosquitoes vector many pathogens that cause human diseases. Repellents play a significant role in reducing the risk of these diseases by preventing mosquito bites. In this paper, we are reporting an Ali and Khan (A & K), large cage in vitro bioassay system that can effectively be used to measure repellency of compounds against mosquitoes. The system uses temperature as a landing and feeding stimulus, and collagen as a feeding substrate. The minimum effective dose (MED) of DEET (N, N-diethyl-meta-toluamide; 19...
May 24, 2017: Journal of Medical Entomology
https://www.readbyqxmd.com/read/28540513/utility-of-3d-printed-temporal-bones-in-pre-surgical-planning-for-complex-bonebridge-cases
#9
Payal Mukherjee, Kai Cheng, Sean Flanagan, Simon Greenberg
With the advent of single-sided hearing loss increasingly being treated with cochlear implantation, bone conduction implants are reserved for cases of conductive and mixed hearing loss with greater complexity. The BoneBridge (BB, MED-EL, Innsbruck, Austria) is an active fully implantable device with no attenuation of sound energy through soft tissue. However, the floating mass transducer (FMT) part of the device is very bulky, which limits insertion in complicated ears. In this study, 3D printed temporal bones of patients were used to study its utility in preoperative planning on complicated cases...
May 24, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28539155/you-re-the-flight-surgeon
#10
(no author information available yet)
Watkins-Nance SM. You're the flight surgeon: atrial septal defect. Aerosp Med Hum Perform. 2017; 88(6):604-607.
June 1, 2017: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/28539154/you-re-the-flight-surgeon
#11
(no author information available yet)
Frayser MR. You're the flight surgeon: Bell's palsy. Aerop Med Hum Perform. 2017; 88(6):601-604.
June 1, 2017: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/28539149/mobility-and-agility-during-locomotion-in-the-mark-iii-space-suit
#12
Conor R Cullinane, Richard A Rhodes, Leia A Stirling
INTRODUCTION: The Mark III (MIII) space suit assembly (SSAs) implements a multibearing, hard-material hip brief assembly (HBA). We hypothesize that: 1) the MIII HBA restricts operator mobility and agility which manifests in effects to gait parameters; 2) the waist bearing provides rotational motion, partially alleviating the restrictions; and 3) there are resistive, speed-dependent torques associated with the spinning bearings which further diminish mobility and agility. METHODS: A subject (Suited and Unsuited) performed two planetary tasks-walking forward (WF) and backward (WB)...
June 1, 2017: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/28539148/localized-heat-urticaria-from-95-ghz-millimeter-waves
#13
John A Gibbons
INTRODUCTION: Local heat urticaria is a physical urticaria caused by the environmental stimulus of heat. Typically, the resultant lesion, a wheal, is pruritic (itches) and is sometimes accompanied by a burning sensation. It is a self-limited phenomenon that resolves after 1.5-2 h. The prevalence of local heat urticaria in the general population has been estimated as 1 in 200,000 persons. CASE REPORT: The subject, a 39-yr-old active duty man, participated in a test of a 95-GHz energy beam designed to heat the skin...
June 1, 2017: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/28539147/sunlight-exposure-work-hours-caffeine-consumption-and-sleep-duration-in-the-naval-environment
#14
Nita L Shattuck, Panagiotis Matsangas
BACKGROUND: Sailors in the U.S. Navy are habitual shiftworkers, often experiencing circadian misalignment due to their irregular work/rest schedules. This study assessed the effect of sunlight exposure, work hours, and caffeinated beverage consumption on the daily sleep duration of crewmembers of a U.S. Navy ship during a 2-wk underway period. METHODS: Working in an artificially lit area with no access to sunlight during work hours, U.S. Navy crew members (N = 91) used daily logs to report their daily activity, caffeinated beverage consumption, and exposure to sunlight while off-duty; sleep was assessed by wrist-worn actigraphy...
June 1, 2017: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/28539146/keratoconus-in-civil-aviation-pilots-in-a-report-of-six-cases
#15
Albert Rebello, Bênesson Rodrigues, Marcos Pereira
BACKGROUND: Keratoconus is a progressive noninflammatory ectatic corneal dystrophy, characterized by corneal thinning and increased curvature with central or paracentral tapered protrusion. Such changes in corneal morphology induce irregular astigmatism and myopia, resulting in visual acuity impairment. This report assesses cases in which keratoconus is not an absolute disabling condition for civil aviation pilots. METHODS: Six cases of keratoconus in active pilots are presented...
June 1, 2017: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/28539145/workplace-social-support-and-behavioral-health-prior-to-long-duration-spaceflight
#16
Charlene A Deming, Jennifer J Vasterling
INTRODUCTION: Preparation and training for long-duration spaceflight bring with them psychosocial stressors potentially affecting the well-being and performance of astronauts, before and during spaceflight. Social support from within the workplace may mitigate behavioral health concerns arising during the preflight period and enhance resiliency before and during extended missions. The purpose of this review was to evaluate evidence addressing the viability of workplace social support as a pre-mission countermeasure, specifically addressing: 1) the observed relationships between workplace social support and behavioral health; 2) perceived need, acceptability, and format preference for workplace social support among high-achievers; 3) potential barriers to delivery/receipt of workplace social support; 4) workplace social support interventions; and 5) delivery timeframe and anticipated duration of workplace social support countermeasure benefits...
June 1, 2017: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/28539144/cirrus-airframe-parachute-system-and-odds-of-a-fatal-accident-in-cirrus-aircraft-crashes
#17
Mustafa Alaziz, Adrienne Stolfi, Dean M Olson
INTRODUCTION: General aviation (GA) accidents have continued to demonstrate high fatality rates. Recently, ballistic parachute recovery systems (BPRS) have been introduced as a safety feature in some GA aircraft. This study evaluates the effectiveness and associated factors of the Cirrus Airframe Parachute System (CAPS) at reducing the odds of a fatal accident in Cirrus aircraft crashes. METHODS: Publicly available Cirrus aircraft crash reports were obtained from the National Transportation Safety Board (NTSB) database for the period of January 1, 2001-December 31, 2016...
June 1, 2017: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/28539143/incidence-of-g-induced-loss-of-consciousness-and-almost-loss-of-consciousness-in-the-royal-air-force
#18
Ellen Slungaard, Judith McLeod, Nicholas D C Green, Amit Kiran, Di J Newham, Stephen D R Harridge
INTRODUCTION: Exposure to sustained +Gz acceleration with inadequate G protection can result in G-induced loss of consciousness (G-LOC) or almost loss of consciousness (A-LOC). The UK Royal Air Force (RAF) last conducted a survey of G-LOC within their military aircrew in 2005 with interventions subsequently introduced. The aim of this study was to repeat the 2005 survey in order to evaluate the impact of those interventions. METHODS: An anonymous questionnaire requesting details of G-LOC and A-LOC events was mailed to all RAF pilots (N = 1878) and weapons systems operators (WSOs) (N = 473), irrespective of aircraft currently flown...
June 1, 2017: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/28539142/inspiratory-muscle-training-effects-on-cycling-during-acute-hypoxic-exposure
#19
Mitch Lomax, Heather C Massey, James R House
INTRODUCTION: Hypoxic environments increase the physiological demands of exercise. Inspiratory muscle training can reduce the demands of exhaustive exercise in this environment. This study examined the impact of inspiratory muscle training on moderate intensity hypoxic cycling exercise. METHODS: There were 17 healthy adult men who undertook 4 wk of inspiratory muscle training (N = 8) or 4 wk of sham inspiratory muscle training (N = 9). Subjects completed four fixed intensity (100 W) and duration (10 min) cycle ergometry tests...
June 1, 2017: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/28539141/individual-traits-personal-values-and-conflict-resolution-in-an-isolated-confined-extreme-environment
#20
Jesper G Corneliussen, Gloria R Leon, Anders Kjærgaard, Birgit A Fink, Noah C Venables
BACKGROUND: The study of personality traits, personal values, and the emergence of conflicts within groups performing in an isolated, confined, and extreme environment (ICE) may provide insights helpful for the composition and support of space crews for long duration missions. METHODS: Studied pre/post and over the 2-yr period of the investigation were 10 Danish military personnel deployed to stations in Greenland on a 26-mo staggered rotation. Subjects completed the NEO PI-R, Triarchic Psychopathy Measure, and Portrait Values Questionnaire, and participated in structured interviews...
June 1, 2017: Aerospace Medicine and Human Performance
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