Sophie Tissot, Lena Guimard, Jordan Meliani, Justine Boutry, Antoine M Dujon, Jean-Pascal Capp, Jácint Tökölyi, Peter A Biro, Christa Beckmann, Laura Fontenille, Nam Do Khoa, Rodrigo Hamede, Benjamin Roche, Beata Ujvari, Aurora M Nedelcu, Frédéric Thomas
The inability to control cell proliferation results in the formation of tumors in many multicellular lineages. Nonetheless, little is known about the extent of conservation of the biological traits and ecological factors that promote or inhibit tumorigenesis across the metazoan tree. Particularly, changes in food availability have been linked to increased cancer incidence in humans, as an outcome of evolutionary mismatch. Here, we apply evolutionary oncology principles to test whether food availability, regardless of the multicellular lineage considered, has an impact on tumorigenesis...
November 14, 2023: Scientific Reports