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psychotic depression

Mario Miniati, Antonella Benvenuti, Elena Bologna, Alessandra Maglio, Biagio Cotugno, Gabriele Massimetti, Simona Calugi, Mauro Mauri, Liliana Dell'Osso
PURPOSE: To investigate the presence of mood spectrum signs and symptoms in patients with anorexia nervosa, restricting subtype (AN-R) or bulimia nervosa (BN). METHOD: 55 consecutive female patients meeting DSM-IV criteria for eating disorders (EDs) not satisfying DSM-IV criteria for Axis I mood disorders were evaluated with the Lifetime Mood Spectrum Self-Report (MOODS-SR) and the Mini-International Neuropsychiatric Interview (MINI). The MOODS-SR explored the subthreshold comorbidity for mood spectrum symptoms in patients not reaching the threshold for a mood disorder Axis I diagnosis...
October 20, 2016: Eating and Weight Disorders: EWD
Julia Granerod, Nicholas W S Davies, Parashar P Ramanuj, Ava Easton, David W G Brown, Sara L Thomas
The true extent of sequelae in encephalitis survivors relative to rates within the general population is not known. This study aimed to quantify increased risks of epilepsy, depressive disorders, anxiety disorders, psychotic disorders, bipolar disorder, cognitive problems, dementia, headache, and alcohol abuse among encephalitis cases. 2460 exposed individuals diagnosed with incident encephalitis in the Clinical Practice Research Datalink and 47,914 unexposed individuals without a history of encephalitis were included...
October 20, 2016: Journal of Neurology
Venu Duddu, Abdulhakim Rhouma, Masood Qureshi, Imran Bashir Chaudhry, Terry Drake, Altaf Sumra, Nusrat Husain
Aims and method The need for an age-appropriate in-patient service for 16- to 17-year-olds led to the development of a 6-bed acute admissions unit in a non-metropolitan county in the UK. We provide a descriptive evaluation of the first 2 years of its operation. All admissions from April 2010 to March 2012 were reviewed, clinical details systematically recorded and descriptively analysed. Results Ninety-seven young people were admitted during this period (a third were compulsorily detained under the Mental Health Act 1983)...
October 2016: BJPsych Bulletin
F Kazour, C Awaida, L Souaiby, S Richa
INTRODUCTION: Cannabis use is very frequent in bipolar disorder and has been found to increase the duration and frequency of manic symptoms while decreasing those of depression. Bipolar patients who use cannabis were shown to have poorer compliance to treatment, more symptoms that are psychotic and a worse prognosis than patients who do not. In this study, we have evaluated the importance of cannabis use among bipolar patients admitted to the Psychiatric Hospital of the Cross, Lebanon (Hôpital Psychiatrique de la Croix [HPC]) as well as the clinical differences between cannabis users and non-users...
October 10, 2016: L'Encéphale
Falk Mancke, Gintarė Kaklauskaitė, Jennifer Kollmer, Markus Weiler
Nitrous oxide (N2O), a long-standing anesthetic, is known for its recreational use, and its consumption is on the rise. Several case studies have reported neurological and psychiatric complications of N2O use. To date, however, there has not been a study using standardized diagnostic procedures to assess psychiatric comorbidities in a patient consuming N2O. Here, we report about a 35-year-old male with magnetic resonance imaging confirmed subacute myelopathy induced by N2O consumption, who suffered from comorbid cannabinoid and nicotine dependence as well as abuse of amphetamines, cocaine, lysergic acid diethylamide, and ketamine...
2016: Substance Abuse and Rehabilitation
Amy McKeever, SueEllen Alderman, Stephanie Luff, Brian DeJesus
Severe and persistent mental illness (SPMI) refers to complex mood disorders that include major depressive disorder with or without psychosis; severe anxiety disorders resistant to treatment; affective psychotic disorders including bipolar affective disorder, schizophrenia, and schizoaffective disorder; and other nonaffective subtypes of schizophrenia. SPMIs affect 1 in 17 people and are among the leading causes of disability and impaired health-related quality of life in the United States. Caring for childbearing women with preexisting SPMI can be challenging for maternal-child health clinicians...
October 2016: Nursing for Women's Health
Katarzyna Prochwicz, Łukasz Gawęda
In this study we examined the hypothesis that depression and anxiety may mediate the relationship between personality traits and both positive and negative psychotic-like experiences (PLEs) in healthy adults. The Community Assessment of Psychic Experiences (CAPE) scale, Temperament and Character Inventory (TCI), Beck Depression Inventory (BDI) and State and Trait Anxiety Inventory (STAI) were administered to 492 healthy individuals. Multiple stepwise regression and mediation analyses were performed to examine whether depressive and anxiety symptoms influence the relationship between the TCI dimensions and positive and negative PLEs...
September 23, 2016: Psychiatry Research
Amadou Jallow, Gunnar Ljunggren, Per Wändell, Lars Wahlström, Axel C Carlsson
CONTEXT: The Greater Stockholm HIV Cohort Study is an initiative to provide longitudinal information regarding the health of people living with HIV. OBJECTIVE: Our aim was to explore the prevalence of HIV and its association with psychiatric co-morbidities. DESIGN, SETTING AND PARTICIPANTS: All patients with a recorded diagnosis of HIV (any position of the ICD-10 codes B20-B24) were identified during the period 2007-2014 and related to the total population in Stockholm by January 1, 2015, N = 2...
October 4, 2016: Journal of Infection
Tolga Binbay, Deniz Arık Binbay, Halis Ulaş, Köksal Alptekin
OBJECTIVE: To provide registry-based prevalence estimates of schizophrenia, schizoaffective, and bipolar I (BPI) disorders in a defined area of Sinop, Turkey. MATERIAL AND METHODS: All patients that presented to primary and secondary health services over three year time (2009-2011) with diagnosis of psychotic disorder (F06.1, F06.2, F10.5, F12.5, F19.5, F20-29, F30-31, F32.3, F33.3, F39 in ICD-10) covering a population of 73,503 aged 15-64 were included via case registry systems...
2016: Türk Psikiyatri Dergisi, Turkish Journal of Psychiatry
Jean-Marc Guilé, Christophe Huynh, Jean-Jacques Breton, Sébastien Garny De La Rivière, Claude Berthiaume, Marie St-Georges, Réal Labelle
INTRODUCTION: Chart review is a low-cost, but highly informative, method to describe symptoms, treatment, and risk factors associated with borderline personality disorder (BPD) and to adapt screening and intervention to clinical reality. Previous chart review studies report more aggressiveness/anger and psychotic features in youths with BPD. They show that adverse family environment and parental psychopathology constitute important factors for BPD pathology. OBJECTIVES: To examine clinical characteristics of depressed BPD adolescents (12-17 years old) outpatients according to gender and to explore variables which are associated with BPD traits...
2016: Frontiers in Pediatrics
E S Gouvea, V K Ota, C Noto, M L Santoro, L M Spindola, P N Moretti, C M Carvalho, G Xavier, A C Rios, J R Sato, M A F Hayashi, E Brietzke, A Gadelha, R A Bressan, Q Cordeiro, S I Belangero
Psychotic disorders affect ~3% of the general population and are among the most severe forms of mental diseases. In early stages of psychosis, clinical aspects may be difficult to distinguish from one another. Undifferentiated psychopathology at the first-episode of psychosis (FEP) highlights the need for biomarkers that can improve and refine differential diagnosis. We investigated gene expression differences between patients with FEP-schizophrenia spectrum (SCZ; N=53) or FEP-Mania (BD; N=16) and healthy controls (N=73)...
October 4, 2016: Translational Psychiatry
Osvaldo P Almeida, Kieran McCaul, Graeme J Hankey, Bu B Yeap, Jonathan Golledge, Leon Flicker
BACKGROUND: Dementia and affective and psychotic symptoms are commonly associated with Parkinson's disease, but information about their prevalence and incidence in community representative samples remains sparse. METHODS: We recruited a community-representative sample 38173 older men aged 65-85 years in 1996 and used data linkage to ascertain the presence of PD, affective disorders, psychotic disorders and dementia. Diagnoses followed the International Classification of Disease coding system...
2016: PloS One
Nina Rautio, Jouko Miettunen, Erika Jääskeläinen, Tanja Nordström, Matti Isohanni, Jussi Seppälä
BACKGROUND: We examined mortality in schizophrenia spectrum disorder (SSD) and non-schizophrenic psychosis (NSSD) compared to individuals without psychosis, and whether perinatal factors predict mortality. METHODS: Within Northern Finland Birth Cohort 1966 (n=10 933; 203 with SSD, 178 with NSSD), mortality was followed until end of 2011 by national register. Wantedness of pregnancy, mother's antenatal depression, smoking and age, parity, paternal socio-economic status (SES) and family type at birth were examined as predictors of mortality...
September 27, 2016: Schizophrenia Research
Helena García-Mieres, Susana Ochoa, Marta Salla, Raquel López-Carrilero, Guillem Feixas
In this paper we illustrate the potential of the repertory grid technique as an instrument for case formulation and understanding of the personal perception and meanings of people with a diagnosis of psychotic disorders. For this purpose, the case of James is presented: A young man diagnosed with schizophrenia and personality disorder, with severe persecutory delusions and other positive symptoms that have not responded to antipsychotic medication, as well with depressive symptomatology. His case was selected because of the way his symptoms are reflected in his personal perception of self and others, including his main persecutory figure, in the different measures that result from the analysis of his repertory grid...
September 22, 2016: World Journal of Psychiatry
Anna L MacKinnon, Mariam Naguib, Helena J Barr, Anna Levinsson, Stephanie Robins, Nancy Feeley, Barbara Hayton, Phyllis Zelkowitz, Ian Gold
BACKGROUND: Despite the prevalence of mental health problems during the perinatal period, little research has examined psychotic symptoms in a community sample across pregnancy and the postpartum. Exposure to environmental risk factors, and immigration in particular, are associated with increased risk for psychotic disorders. The current investigation examined whether psychosocial risk and immigrant status would predict levels of delusional ideation across the perinatal period when controlling for depression, anxiety, and demographic factors...
September 23, 2016: Schizophrenia Research
Chikako Kaneko, Norshalena Shakespear, Mario Tuchiya, Jin Kubo, Teiji Yamamoto, Soichi Katayama, Yukitoshi Takahashi
Five consecutive cases of anti-NMDA-receptor encephalitis that we encountered were marked by a rapidly fluctuating level of consciousness associated with psychotic and delirious mental states. Opisthotonus, catatonia, and rhythmic and non-rhythmic involuntary movements of the mouth and jaw were also characteristic features of these particular cases. Serious and potentially fatal problems included epilepsia partialis continua, partial and generalized seizures, and respiratory depression, resembling the symptoms of encephalitis lethargica...
September 2016: Brain and Nerve, Shinkei Kenkyū No Shinpo
Aloise de Codt, Pauline Monhonval, Xavier Bongaerts, Ikram Belkacemi, Juan Martin Tecco
BACKGROUND: Bipolar disorder is a chronic psychiatric disease with a high prevalence and is a major psychosocial and medical burden. The exact etiological pathways of bipolar disorder are not fully understood. Genetic factors are known to play an important role in the etiology of bipolar disorder. However, high rates of discordance among identical twins and a growing body of evidence that environmental factors such as early stress can influence the onset and course of psychiatric diseases underline the importance of additional etiological mechanisms of bipolar disorders...
September 2016: Psychiatria Danubina
Marcin Siwek, Magdalena Sowa-Kućma, Krzysztof Styczeń, Paulina Misztak, Rafał J Nowak, Bernadeta Szewczyk, Dominika Dudek, Janusz K Rybakowski, Gabriel Nowak, Michael Maes
To examine cytokine receptor biomarkers in bipolar disorder (BD), we recruited 133 well-phenotyped BD patients and 50 normal controls and measured serum levels of soluble interleukin 1 receptor antagonist (sIL-1RA), soluble interleukin-2 receptor (sIL-2R), sIL-6R, and tumor necrosis factor receptor 60 and 80 kDa (sTNFR60/80). sIL-1RA and sTNFR80 are significantly higher in BD than in controls and sTNFR80 and higher in melancholic than in non-melancholic patients and controls. Kapczinski's stages 3 + 4 are characterized by lowered sIL-2R and increased sTNFR80 levels...
September 23, 2016: Molecular Neurobiology
Bizu Gelaye, Marta B Rondon, Ricardo Araya, Michelle A Williams
Maternal depression, a non-psychotic depressive episode of mild to major severity, is one of the major contributors of pregnancy-related morbidity and mortality. Maternal depression (antepartum or post partum) has been linked to negative health-related behaviours and adverse outcomes, including psychological and developmental disturbances in infants, children, and adolescents. Despite its enormous burden, maternal depression in low-income and middle-income countries remains under-recognised and undertreated...
October 2016: Lancet Psychiatry
Santiago Navarro, Fernando Rodríguez, Francisco J Acosta, Miguel García-Bello
INTRODUCTION: Nonadherence is an important and highly prevalent issue in bipolar disorder, which may have serious consequences. Surprisingly, few studies have been carried out in patients with clinical stability to explore risk factors for nonadherence. METHOD: Adherence was assessed in 76 bipolar disorder patients with clinical stability using objective and subjective methods, both with a cross-sectional approach and a 3-year retrospective period. Possible associations between nonadherence and sociodemographic, clinical, treatment-related, psychopathological, psychological-subjective and result variables were also assessed...
September 2016: Actas Españolas de Psiquiatría
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