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psychotic depression

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https://www.readbyqxmd.com/read/28109668/childhood-trauma-depression-and-negative-symptoms-are-independently-associated-with-impaired-quality-of-life-in-schizophrenia-results-from-the-national-face-sz-cohort
#1
M Andrianarisoa, L Boyer, O Godin, L Brunel, E Bulzacka, B Aouizerate, F Berna, D Capdevielle, J M Dorey, C Dubertret, J Dubreucq, C Faget, F Gabayet, P M Llorca, J Mallet, D Misdrahi, R Rey, R Richieri, C Passerieux, A Schandrin, A M Tronche, M Urbach, P Vidailhet, F Schürhoff, G Fond
OBJECTIVES: Depression and negative symptoms have been associated with impaired Quality of life (QoL) in schizophrenia (SZ). However, childhood trauma may influence both QoL and depression in SZ patients, with consequences for the management of impaired QoL in SZ patients. The aim of the present study was to determine if childhood trauma was associated with impaired QoL in schizophrenia. METHOD: A sample of 544 community-dwelling stabilized SZ patients enrolled in FACE-SZ cohort were utilized in this study (74...
January 18, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/28107668/neurotrophins-role-in-depressive-symptoms-and-executive-function-performance-association-analysis-of-nrn1-gene-and-its-interaction-with-bdnf-gene-in-a-non-clinical-sample
#2
C Prats, B Arias, G Ortet, M I Ibáñez, J Moya, E Pomarol-Clotet, L Fañanás, M Fatjó-Vilas
BACKGROUND: Neuritin-1 is a neurotrophic factor involved in synaptic plasticity that has been associated with depressive disorders, schizophrenia and cognitive performance. The study of genotype-phenotype relationships in healthy individuals is a useful framework to investigate the etiology of brain dysfunctions. We therefore aimed to investigate in a non-clinical sample whether NRN1 gene contributes to the psychopathological profile, with a particular focus on the clinical dimensions previously related to the NRN1 gene (i...
November 23, 2016: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28100210/prevalence-of-psychiatric-morbidity-in-a-community-sample-in-western-kenya
#3
Edith Kwobah, Steve Epstein, Ann Mwangi, Debra Litzelman, Lukoye Atwoli
BACKGROUND: About 25% of the worldwide population suffers from mental, neurological and substance use disorders but unfortunately, up to 75% of affected persons do not have access to the treatment they need. Data on the magnitude of the mental health problem in Kenya is scarce. The objectives of this study were to establish the prevalence and the socio-demographic factors associated with mental and substance use disorders in Kosirai division, Nandi County, Western Kenya. METHODS: This was a cross sectional descriptive study in which participants were selected by simple random sampling...
January 18, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28097648/a-systematic-review-and-meta-analysis-of-prospective-transition-from-major-depression-to-bipolar-disorder
#4
A Ratheesh, C Davey, S Hetrick, M Alvarez-Jimenez, C Voutier, A Bechdolf, P D McGorry, J Scott, M Berk, S M Cotton
OBJECTIVE: Some people with major depressive disorder (MDD) may be at a pre-onset stage for bipolar disorder (BD), where early identification or prevention efforts may be feasible. We aimed to identify rates and characteristics predictive of transition to BD in prospective follow-up studies of people with MDD. METHODS: Using a systematic search strategy, we identified studies with a diagnostic ascertainment of MDD and BD of an adequate standard, and where the minimum length of follow-up was 6 months...
January 18, 2017: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/28077602/diagnoses-of-sexual-abuse-and-their-common-registered-comorbidities-in-the-total-population-of-stockholm
#5
Gita Rajan, Gunnar Ljunggren, Per Wändell, Lars Wahlström, Carl-Göran Svedin, Axel C Carlsson
BACKGROUND: Prior research based on self-reports has proven sexual abuse to be a risk factor for pain and psychiatric disorders. However, less is known about how this is reflected within the healthcare system. The aim of this study was to study the 2-year prevalence of diagnosis of sexual abuse and concomitant conditions. METHODS: Using data from VAL, the study population included all living persons in Stockholm County, Sweden, between 1 January 2008 and 31 December 2014 (N=2 549 496)...
January 11, 2017: Journal of Epidemiology and Community Health
https://www.readbyqxmd.com/read/28072643/early-life-trauma-in-hospitalized-patients-with-mood-disorders-and-its-association-with-clinical-outcomes
#6
Ajay K Parsaik, Noha Abdelgawad, Jigar K Chotalia, Scott D Lane, Teresa A Pigott
BACKGROUND: The prevalence of childhood trauma and its impact on clinical outcomes in hospitalized patients with mood disorders is unknown. We studied the frequency of childhood trauma among inpatient adults with mood disorders and its association with clinical outcomes. METHODS: Patients admitted to our hospital with a primary diagnosis of mood disorders completed the short form of the Early Trauma Inventory-Self-Report (ETISR-SF), the Sheehan Disability Scale, and the Clinician-Rated Dimensions of Psychosis Symptom Severity scale...
January 2017: Journal of Psychiatric Practice
https://www.readbyqxmd.com/read/28065176/behavioural-and-psychological-symptoms-in-general-hospital-patients-with-dementia-distress-for-nursing-staff-and-complications-in-care-results-of-the-general-hospital-study
#7
J B Hessler, M Schäufele, I Hendlmeier, M N Junge, S Leonhardt, J Weber, H Bickel
AIMS: Little is known about how behavioural and psychological symptoms of dementia (BPSD) manifest in the general hospital. The aim was to examine the frequency of BPSD in general hospitals and their associations with nursing staff distress and complications in care. METHODS: Cross-sectional representative study with 1469 patients aged ≥65, including 270 patients with dementia, of 33 randomly selected general hospitals in Germany. BPSD and complications were reported by nurses...
January 9, 2017: Epidemiology and Psychiatric Sciences
https://www.readbyqxmd.com/read/28050894/patients-with-preexisting-psychiatric-disorders-admitted-to-icu-a-descriptive-and-retrospective-cohort-study
#8
Arnaud Gacouin, Adel Maamar, Pierre Fillatre, Emmanuelle Sylvestre, Margaux Dolan, Yves Le Tulzo, Jean Marc Tadié
BACKGROUND: While the psychiatric disorders are conditions frequently encountered in hospitalized patients, there are little or no data regarding the characteristics and short- and long-term outcomes in patients with preexisting psychiatric disorders in ICU. Such assessment may provide the opportunity to determine the respective impact on mortality in the ICU and after ICU discharge with reasons for admission, including modalities of self-harm, of underlying psychiatric disorders and prior psychoactive medications...
December 2017: Annals of Intensive Care
https://www.readbyqxmd.com/read/28049620/how-do-people-experiencing-schizophrenia-spectrum-disorders-or-other-psychotic-disorders-use-the-internet-to-get-information-on-their-mental-health-literature-review-and-recommendations
#9
Murielle Villani, Viviane Kovess-Masfety
BACKGROUND: Studies show that the Internet has become an influential source of information for people experiencing serious psychiatric conditions such as schizophrenia spectrum disorders or other psychotic disorders, among which the rate of Internet users is growing, with rates ranging from 33.3% to 79.5% given the country. Between 20.5% and 56.4% of these Internet users seek mental health information. OBJECTIVE: Focusing on this population's Web searches about their mental health, this paper examines what type of content they look for and what could be the benefits and disadvantages of this navigation...
January 3, 2017: JMIR Mental Health
https://www.readbyqxmd.com/read/28049102/prevalence-and-clinical-severity-of-mood-disorders-among-first-second-and-third-generation-migrants
#10
Baptiste Pignon, Geoffroy Pierre Alexis, Pierre Thomas, Jean-Luc Roelandt, Benjamin Rolland, Craig Morgan, Guillaume Vaiva, Ali Amad
BACKGROUND: The role of migration as a risk factor remains unknown for mood disorders because of poor data. We sought to examine the prevalence and severity of mood disorders (bipolar disorder (BD), unipolar depressive disorder (UDD) and dysthymia) in first, second, and third generation migrants in France. METHODS: The Mental Health in the General Population survey interviewed 38,694 individuals. The prevalence of lifetime mood disorders, comorbidities, and clinical features was compared between migrants and non-migrants and by generation...
December 27, 2016: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28049083/recovery-assessment-scale-examining-the-factor-structure-of-the-german-version-ras-g-in-people-with-schizophrenia-spectrum-disorders
#11
M Cavelti, M Wirtz, P Corrigan, R Vauth
BACKGROUND: The recovery framework has found its way into local and national mental health services and policies around the world, especially in English speaking countries. To promote this process, it is necessary to assess personal recovery validly and reliably. The Recovery Assessment Scale (RAS) is the most established measure in recovery research. The aim of the current study is to examine the factor structure of the German version of the RAS (RAS-G). METHODS: One hundred and fifty-six German-speaking clients with schizophrenia or schizoaffective disorder from a community mental health service completed the RAS-G plus measures of recovery attitudes, self-stigma, psychotic symptoms, depression, and functioning...
December 30, 2016: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/28045285/a-pragmatic-randomized-clinical-trial-of-behavioral-activation-for-depressed-pregnant-women
#12
Sona Dimidjian, Sherryl H Goodman, Nancy E Sherwood, Gregory E Simon, Evette Ludman, Robert Gallop, Stacy Shaw Welch, Jennifer M Boggs, Christina A Metcalf, Sam Hubley, J David Powers, Arne Beck
OBJECTIVE: Depression among pregnant women is a prevalent public health problem associated with poor maternal and offspring development. Behavioral activation (BA) is a scalable intervention aligned with pregnant women's preference for nonpharmacological depression care. This is the first test of the effectiveness of BA for depression among pregnant women, which aimed to evaluate the effectiveness of BA as compared with treatment as usual (TAU). METHOD: Pregnant women (mean age = 28...
January 2017: Journal of Consulting and Clinical Psychology
https://www.readbyqxmd.com/read/28040575/stigma-toward-psychosis-and-its-formulation-process-prejudice-and-discrimination-against-early-stages-of-schizophrenia
#13
Yoko Baba, Takahiro Nemoto, Naohisa Tsujino, Taiju Yamaguchi, Naoyuki Katagiri, Masafumi Mizuno
BACKGROUND: Stigma toward psychosis can prevent social attendance and help-seeking behavior. Early detection and intervention has been shown to improve patient outcome in schizophrenia. The aim of this study was to reveal the characteristics and formulation process of stigma toward each clinical stage of schizophrenia, taking people's backgrounds into consideration. METHODS: The participants consisted of three groups: general public, patients with mental illness, and psychiatric professionals...
November 17, 2016: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/28035924/the-effect-of-the-association-between-donepezil-and-choline-alphoscerate-on-behavioral-disturbances-in-alzheimer-s-disease-interim-results-of-the-ascomalva-trial
#14
Anna Carotenuto, Raffaele Rea, Enea Traini, Angiola Maria Fasanaro, Giovanna Ricci, Valentino Manzo, Francesco Amenta
BACKGROUND: Behavioral and psychological symptoms of dementia (BPSD) are a group of psychological reactions, psychiatric symptoms, and behaviors commonly found in Alzheimer's disease (AD). Four clusters of BPSD have been described: mood disorders (depression, anxiety, and apathy), psychotic symptoms (delusions and hallucinations), aberrant motor behaviors (pacing, wandering, and other purposeless behaviors), and inappropriate behaviors (agitation, disinhibition, and euphoria). Most of them are attributed to acetylcholine deficiency...
December 30, 2016: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28033511/vitamin-d-and-alcohol-a-review-of-the-current-literature
#15
REVIEW
Vitor Soares Tardelli, Mariana Pimentel Pádua do Lago, Dartiu Xavier da Silveira, Thiago Marques Fidalgo
Vitamin D is associated with bone mineral density, and its deficiency is a global health problem. In psychiatry, low vitamin D levels have been associated with schizophrenia, depression, psychotic symptoms, and, more recently, alcohol use disorders. Alcohol use disorders are among the most prevalent mental disorders worldwide. Therefore, our aim was to evaluate the association between alcohol use and vitamin D serum levels. The PubMed, SCIELO, and Lilacs databases were searched for this systematic review. We assessed all articles published from 1976 to December 2015, and we examined the associated reference lists to retrieve articles that appeared to fulfill our criteria...
February 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28031586/clinical-correlates-of-suicide-in-suicidal-patients-with-schizophrenia-spectrum-disorders-and-affective-disorders
#16
Hemendra Singh, Prabha S Chandra, V Senthil Kumar Reddi
BACKGROUND: The most common psychiatric illnesses in the background of suicide are schizophrenia spectrum disorders (SSD) and affective disorders (AD). While depression and hopelessness are important factors for suicide in psychiatric patients, the role of psychotic symptoms is unclear. We examine the comparative differences in the clinical correlates of suicide in SSD and AD patients with suicidal risk. MATERIALS AND METHODS: One hundred and twenty suicidal psychiatric patients (aged between 17-60 years) were evaluated for depression severity, hopelessness, past attempts, and reasons for wanting to commit suicide at the emergency psychiatry centre...
November 2016: Indian Journal of Psychological Medicine
https://www.readbyqxmd.com/read/28031038/using-a-smartphone-app-to-reduce-cognitive-vulnerability-and-mild-depressive-symptoms-study-protocol-of-an-exploratory-randomized-controlled-trial
#17
Cezar Giosan, Cristina Mogoaşe, Oana Cobeanu, Aurora Szentágotai Tătar, Vlad Mureşan, Rareș Boian
BACKGROUND: Depression is a major challenge worldwide, with significant increasing personal, economic, and societal costs. Although empirically supported treatments have been developed, they are not always available for patients in routine clinical care. Therefore, we need effective and widely accessible strategies to prevent the onset of the very first depressive symptoms. Mental health apps could prove a valuable solution for this desideratum. Although preliminary research has indicated that such apps can be useful in treating depression, no study has attempted to test their utility in preventing depressive symptoms...
December 28, 2016: Trials
https://www.readbyqxmd.com/read/28025071/th17-cells-correlate-positively-to-the-structural-and-functional-integrity-of-the-brain-in-bipolar-depression-and-healthy-controls
#18
Sara Poletti, Harm de Wit, Elena Mazza, Annemarie J M Wijkhuijs, Clara Locatelli, Veronica Aggio, Cristina Colombo, Francesco Benedetti, Hemmo A Drexhage
: Abnormalities of T cell-mediated immune activation, in the absence of active somatic immune diseases, have consistently been reported in mood disorders. Apart from being important players in the regulation of cells of the immune system, T cells are essential for normal brain development. We here report studies on the relationship between circulating levels of T helper cells and structural and functional brain imaging in depressed bipolar patients. Since the CCL20-CCR6 axis is an important entry to the brain we differentiated the various T helper cell subpopulations on the basis of their chemokine receptor expression...
December 23, 2016: Brain, Behavior, and Immunity
https://www.readbyqxmd.com/read/28009624/time-trends-and-variations-in-electroconvulsive-treatment-in-denmark-2008-to-2014-a-nationwide-register-based-study
#19
Eva Hundrup, Merete Osler, Martin Balslev Jørgensen
OBJECTIVE: The aim of this study was to determine status and variations in the practice of electroconvulsive treatment (ECT) in Denmark in patient characteristics, indications, treatment patterns, and hospital region. METHOD: All 140,627 ECTs registered in the Danish National Patient Registry between 2008 and 2014 were retrieved together with information on patient characteristics. Annual treated person rates were calculated for sex, age, admission diagnosis, and region...
December 21, 2016: Journal of ECT
https://www.readbyqxmd.com/read/28006664/the-high-burden-of-traumatic-brain-injury-and-comorbidities-amongst-homeless-adults-with-mental-illness
#20
Jane Topolovec-Vranic, Andree Schuler, Agnes Gozdzik, Julian Somers, Paul-Émile Bourque, C James Frankish, Jalila Jbilou, Sarah Pakzad, Luis Ivan Palma Lazgare, Stephen W Hwang
OBJECTIVE: characterize the prevalence of self-reported head injury with loss of consciousness (LOC) and associated demographic, clinical and service use factors in a sample of homeless adults with mental illness. METHOD: Participants in the At Home/Chez Soi study were interviewed at the time of study enrollment regarding their history of head injuries, mental and physical health diagnoses and justice system and healthcare interactions. Sociodemographic and clinical data were also collected...
December 3, 2016: Journal of Psychiatric Research
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