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https://www.readbyqxmd.com/read/28193762/teaching-neuroimages-ocular-findings-in-a-patient-with-wilson-disease-and-venous-sinus-thrombosis
#1
Ivana Vodopivec, Emer McGrath, Henrikas Vaitkevicius
No abstract text is available yet for this article.
February 14, 2017: Neurology
https://www.readbyqxmd.com/read/28186618/study-of-individualization-and-bias-in-nursing-home-fall-prevention-practices
#2
Cathleen S Colón-Emeric, Kirsten Corazzini, Eleanor McConnell, Wei Pan, Mark Toles, Rasheeda Hall, Melissa Batchelor-Murphy, Tracey L Yap, Amber L Anderson, Andrew Burd, Ruth A Anderson
OBJECTIVES: Little is known about how nursing home staff use resident characteristics to individualize care delivery or whether care is affected by implicit bias. DESIGN: Randomized factorial clinical vignette survey. SETTING: Sixteen nursing homes in North Carolina. PARTICIPANTS: Nursing, rehabilitation, and social services staff (n = 433). MEASUREMENTS: Vignettes describing hypothetical residents were generated from a matrix of clinical and demographic characteristics...
February 10, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28183843/left-atrial-size-and-function-in-hypertrophic-cardiomyopathy-patients-and-risk-of-new-onset-atrial-fibrillation
#3
Philippe Debonnaire, Emer Joyce, Yasmine Hiemstra, Bart J Mertens, Douwe E Atsma, Martin J Schalij, Jeroen J Bax, Victoria Delgado, Nina Ajmone Marsan
BACKGROUND: The value of left atrial (LA) diameter, volume, and strain to risk stratify hypertrophic cardiomyopathy patients for new-onset atrial fibrillation (AF) was explored. METHODS AND RESULTS: A total of 242 hypertrophic cardiomyopathy patients without AF history were evaluated by (speckle-tracking) echocardiography. During mean follow-up of 4.8±3.7 years, 41 patients (17%) developed new-onset AF. Multivariable analysis showed LA volume (≥37 mL/m(2); hazard ratio, 2...
February 2017: Circulation. Arrhythmia and Electrophysiology
https://www.readbyqxmd.com/read/28165695/is-there-a-cure-for-violence
#4
Charles Bouchard
If you want to avoid violence, stay away from hospitals. The first time I went to an emer- gency room, to pick up an elderly friar who had taken a fall, I was shocked to encounter armed guards, metal detectors, police officers and even a handcuffed prisoner sitting in the waiting area. Was I in a hospital or a jail? This brief, daytime experience changed my im- age of emergency care forever. Since that first visit, I have learned that things are even worse than they appeared that day. Hospitals are dangerous places...
July 2016: Health Progress
https://www.readbyqxmd.com/read/28165618/experimental-comparison-of-efficacy-for-three-handfeeding-techniques-in-dementia
#5
Melissa K Batchelor-Murphy, Eleanor S McConnell, Elaine J Amella, Ruth A Anderson, Connie W Bales, Susan Silva, Angel Barnes, Cornelia Beck, Cathleen S Colon-Emeric
BACKGROUND: Nursing home (NH) residents who require assistance during mealtimes are at risk for malnutrition. Supportive handfeeding is recommended, yet there is limited evidence supporting use of a specific handfeeding technique to increase meal intake. OBJECTIVES: To compare efficacy of three handfeeding techniques for assisting NH residents with dementia with meals: Direct Hand (DH), Over Hand (OH), and Under Hand (UH). DESIGN: A prospective pilot study using a within-subjects experimental Latin square design with randomization to one of three handfeeding technique sequences...
February 6, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28164106/mir-21-alters-circulating-treg-function-in-vascular-disease-hope-for-restoring-immunoregulatory-responses-in-atherosclerosis
#6
COMMENT
Emer E Hackett, Frederick J Sheedy
No abstract text is available yet for this article.
January 2017: Annals of Translational Medicine
https://www.readbyqxmd.com/read/28153637/early-development-of-structural-networks-and-the-impact-of-prematurity-on-brain-connectivity
#7
Dafnis Batalle, Emer J Hughes, Hui Zhang, J-Donald Tournier, Nora Tusor, Paul Aljabar, Luqman Wali, Daniel C Alexander, Joseph V Hajnal, Chiara Nosarti, A David Edwards, Serena J Counsell
Preterm infants are at high risk of neurodevelopmental impairment, which may be due to altered development of brain connectivity. We aimed to (i) assess structural brain development from 25 to 45 weeks gestational age (GA) using graph theoretical approaches and (ii) test the hypothesis that preterm birth results in altered white matter network topology. Sixty-five infants underwent MRI between 25(+3) and 45(+6) weeks GA. Structural networks were constructed using constrained spherical deconvolution tractography and were weighted by measures of white matter microstructure (fractional anisotropy, neurite density and orientation dispersion index)...
January 30, 2017: NeuroImage
https://www.readbyqxmd.com/read/28146211/recommendation-of-early-surgery-in-primary-mitral-regurgitation-pros-and-cons
#8
Levent Cerit, Vitor Emer Egypto Rosa, Flávio Tarasoutchi
No abstract text is available yet for this article.
January 2017: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/28129334/a-novel-positron-emission-tomography-pet-approach-to-monitor-cardiac-metabolic-pathway-remodeling-in-response-to-sunitinib-malate
#9
Alice C O'Farrell, Rhys Evans, Johanna M U Silvola, Ian S Miller, Emer Conroy, Suzanne Hector, Maurice Cary, David W Murray, Monika A Jarzabek, Ashwini Maratha, Marina Alamanou, Girish Mallya Udupi, Liam Shiels, Celine Pallaud, Antti Saraste, Heidi Liljenbäck, Matti Jauhiainen, Vesa Oikonen, Axel Ducret, Paul Cutler, Fionnuala M McAuliffe, Jacques A Rousseau, Roger Lecomte, Suzanne Gascon, Zoltan Arany, Bonnie Ky, Thomas Force, Juhani Knuuti, William M Gallagher, Anne Roivainen, Annette T Byrne
Sunitinib is a tyrosine kinase inhibitor approved for the treatment of multiple solid tumors. However, cardiotoxicity is of increasing concern, with a need to develop rational mechanism driven approaches for the early detection of cardiac dysfunction. We sought to interrogate changes in cardiac energy substrate usage during sunitinib treatment, hypothesising that these changes could represent a strategy for the early detection of cardiotoxicity. Balb/CJ mice or Sprague-Dawley rats were treated orally for 4 weeks with 40 or 20 mg/kg/day sunitinib...
2017: PloS One
https://www.readbyqxmd.com/read/28099161/menstrual-cycle-and-the-temporal-discrimination-threshold
#10
Eavan M Mc Govern, Emer O'Connor, Ines Beiser, Laura Williams, John S Butler, Brendan Quinlivan, Shruti Narasiham, Rebecca Beck, Richard B Reilly, Sean O'Riordan, Michael Hutchinson
The temporal discrimination threshold (TDT) is a proposed pre-clinical biomarker (endophenotype) for adult onset isolated focal dystonia (AOIFD). Age- and sex-related effects on temporal discrimination demonstrate that women, before the age of 40 years, have faster temporal discrimination than men but their TDTs worsen with age at almost three times the rate of men. Thus after 40 years the TDT in women is progressively worse than in men. AOIFD is an increasingly female-predominant disorder after the age of 40; it is not clear whether this age-related sexually-dimorphic difference observed for both the TDT and sex ratio at disease onset in AOIFD is a hormonal or chromosomal effect...
January 18, 2017: Physiological Measurement
https://www.readbyqxmd.com/read/28095556/combination-therapy-for-acne-scarring-personal-experience-and-clinical-suggestions
#11
Lucija Kroepfl, Jason J Emer
Acne is one of the most prevalent skin conditions seen by dermatologists. The cosmetic sequelae of severe acne, including scarring and pigmentation, have a profound psychological impact on those in icted. Topical (eg, retinoids, antibiotics, dapsone, hydroxyacids) and oral treatments (eg, antibiotics and/or spironolactone) are often bene cial to control acne or in the instance of oral isotretinoin use, rid the acne permanently; however, these treatments have very little affect on the ultimate cosmetic outcome of the acne scarring and skin texture that results...
November 1, 2016: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/28081099/high-order-external-cavity-modes-and-restabilization-of-a-laser-diode-subject-to-a-phase-conjugate-feedback
#12
Émeric Mercier, Lionel Weicker, Delphine Wolfersberger, Deborah M Kane, Marc Sciamanna
We experimentally report the sequence of bifurcations destabilizing and restabilizing a laser diode with phase-conjugate feedback when the feedback rate is increased. Specifically, we successively observe the initial steady state, undamped relaxation oscillations, quasi-periodicity, chaos, and oscillating solutions at harmonics up to 13 times the external cavity frequency but also the restabilization to a steady state. The experimental results are qualitatively well reproduced by a model that accounts for the time the light takes to penetrate the phase-conjugate mirror...
January 15, 2017: Optics Letters
https://www.readbyqxmd.com/read/28039855/use-of-oral-anticoagulant-therapy-in-older-adults-with-atrial-fibrillation-after-acute-ischemic-stroke
#13
Emer R McGrath, Alan S Go, Yuchiao Chang, Leila H Borowsky, Margaret C Fang, Kristi Reynolds, Daniel E Singer
OBJECTIVES: To explore barriers to anticoagulation in older adults with atrial fibrillation (AF) at high risk of stroke and to identify opportunities for interventions that might increase use of oral anticoagulants (OACs). DESIGN: Retrospective cohort study. SETTING: Two large community-based AF cohorts. PARTICIPANTS: Individuals with ischemic stroke surviving hospitalization (N = 1,405, mean age 79). MEASUREMENTS: Using structured chart review, reasons for nonuse of OAC were identified, and 1-year poststroke survival was assessed...
February 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28027554/features-of-coronary-heart-disease-development-in-emergency-workers-of-the-chornobyl-accident-depending-on-the-action-of-radiation-and-non-radiation-risk-factors-and-genotypes-of-single-nucleotide-polymorphism-rs966221-of-phosphodiesterase-4d-gene
#14
D Belyi, G Pleskach, O Nastina, G Sidorenko, N Kursina, O Bazyka, O Kovalev, A Chumak, I Abramenko
OBJECTIVE: This study devoted to specific features of coronary heart disease (CHD) development in emergency work ers (EW) of the accident at the Chernobyl nuclear power plant (ChNPP) based on analysis the interaction between radiation and non radiation risk factors and single nucleotide polymorphism (SNP) rs966221 of phosphodiesterase (PDE) 4D gene. METHODS: It was examined 397 men with CHD, including 274 EW of 1986-1987 and 123 non irradiated persons (con trol group) who were 66±10 and 69±11 years old relatively...
December 2016: Problemy Radiat︠s︡iĭnoï Medyt︠s︡yny Ta Radiobiolohiï
https://www.readbyqxmd.com/read/27993699/gastroesophageal-mucosal-injury-after-cholecystectomy-an-indication-for-surveillance
#15
Syeda Nadia Shah Gilani, Gary Alan Bass, Natallia Kharytaniuk, Michelle R Downes, Emer Frances Caffrey, Iqbal Tobbia, Thomas Noel Walsh
BACKGROUND: Cholecystectomy alters bile release dynamics from pulsatile meal-stimulated to continuous, and results in retrograde duodeno-gastric bile reflux(DGR). Bile is implicated in mucosal injury following gastric surgery, but whether cholecystectomy causes esophago-gastric mucosal inflammation, thus increasing the risk of metaplasia, is unclear. STUDY DESIGN: This study examined whether cholecystectomy-induced DGR promotes chronic inflammatory mucosal changes of the stomach and/or at the esophago-gastric junction(EGJ)...
December 16, 2016: Journal of the American College of Surgeons
https://www.readbyqxmd.com/read/27984631/interim-assessment-of-liver-damage-in-patients-with-sickle-cell-disease-using-new-non-invasive-techniques
#16
Emma Drasar, Emer Fitzpatrick, Kate Gardner, Moji Awogbade, Anil Dhawan, Adrian Bomford, Abid Suddle, Swee L Thein
We explored transient elastography (TE) and enhanced liver fibrosis (ELF(™) ) score with standard markers of liver function to assess liver damage in 193 well patients with sickle cell disease (SCD). Patients with HbSS or HbSβ(0) thalassaemia (sickle cell anaemia, SCA; N = 134), had significantly higher TE results and ELF scores than those with HbSC (N = 49) disease (TE, 6·8 vs. 5·3, P < 0·0001 and ELF, 9·2 vs. 8·6 P < 0·0001). In SCA patients, TE and ELF correlated significantly with age and all serum liver function tests (LFTs)...
February 2017: British Journal of Haematology
https://www.readbyqxmd.com/read/27929376/pharmaceutical-regulation-in-15-european-countries-review
#17
Dimitra Panteli, Francis Arickx, Irina Cleemput, Guillaume Dedet, Helen Eckhardt, Emer Fogarty, Sophie Gerkens, Cornelia Henschke, Jennifer Hislop, Claudio Jommi, Daphne Kaitelidou, Pawel Kawalec, Ilmo Keskimaki, Madelon Kroneman, Julio Lopez Bastida, Pedro Pita Barros, Joakim Ramsberg, Peter Schneider, Susan Spillane, Sabine Vogler, Lauri Vuorenkoski, Helle Wallach Kildemoes, Olivier Wouters, Reinhard Busse
In the context of pharmaceutical care, policy-makers repeatedly face the challenge of balancing patient access to effective medicines with affordability and rising costs. With the aim of guiding the health policy discourse towards questions that are important to actual and potential patients, this study investigates a broad range of regulatory measures, spanning marketing authorization to generic substitution and resulting price levels in a sample of 16 European health systems (Austria, Belgium, Denmark, England, Finland, France, Germany, Greece, Ireland, Italy, the Netherlands, Poland, Portugal, Scotland, Spain and Sweden)...
October 2016: Health Systems in Transition
https://www.readbyqxmd.com/read/27919409/physiotherapy-managers-perceptions-of-their-leadership-effectiveness-a-multi-frame-analysis
#18
Emer McGowan, Cathal Walsh, Emma Stokes
OBJECTIVES: The purpose of this study was to investigate the leadership frames of physiotherapy managers in Ireland. To be effective leaders in today's challenging healthcare environment physiotherapy managers must employ a comprehensive, adaptable and balanced leadership style. DESIGN: This was a purposive, cross-sectional study. PARTICIPANTS: Physiotherapy managers were surveyed using the Bolman and Deal Leadership Orientations Instrument...
July 18, 2016: Physiotherapy
https://www.readbyqxmd.com/read/27909357/perceptions-of-leadership-comparing-canadian-and-irish-physiotherapists-views
#19
Emer McGowan, Gillian Martin, Emma Stokes
Purpose: To contribute to the growing body of research on leadership in physiotherapy by comparing leadership-related perceptions of physiotherapists in Ireland and in Canada. Methods: This article compares the results of a survey of Canadian physiotherapists with those of the same survey administered to Irish physiotherapists. The results of both studies have previously been reported and are used here to allow a cultural comparison of the perceptions of physiotherapists. The present study used two-portion Z-tests to compare the percentage of physiotherapists in Ireland who self-declared as a leader with the percentage of physiotherapists in Canada who did so...
2016: Physiotherapy Canada. Physiothérapie Canada
https://www.readbyqxmd.com/read/27908391/prevalence-profile-and-prognosis-of-severe-obesity-in-contemporary-hospitalized-heart-failure-trial-populations
#20
Emer Joyce, Anuradha Lala, Susanna R Stevens, Lauren B Cooper, Omar F AbouEzzeddine, John D Groarke, Justin L Grodin, Eugene Braunwald, Kevin J Anstrom, Margaret M Redfield, Lynne W Stevenson
OBJECTIVES: This study evaluated the prevalence, profile, and prognosis of severe obesity in a large contemporary acute heart failure (AHF) population. BACKGROUND: Better prognosis has been reported for obese heart failure (HF) patients than nonobese HF patients, but in other cardiovascular populations, this effect has not been demonstrated for severely obese patients. METHODS: A cohort of 795 participants with body mass index (BMI) measured at time of admission and complete follow-up were identified from enrollment in 3 contemporary AHF trials (DOSE [Diuretic Strategies Optimization Evaluation], CARRESS-HF [Cardiorenal Rescue Study in Acute Decompensated Heart Failure], and ROSE [Renal Optimization Strategies Evaluation in Acute Heart Failure])...
December 2016: JACC. Heart Failure
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