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https://www.readbyqxmd.com/read/27915283/distributions-and-relationships-of-virio-and-pico-plankton-in-the-epi-meso-and-bathy-pelagic-zones-of-the-western-pacific-ocean
#1
Yantao Liang, Yongyu Zhang, Yao Zhang, Tingwei Luo, Richard B Rivkin, Nianzhi Jiao
Virio- and pico-plankton mediate important biogeochemical processes and the environmental factors which regulates their dynamics and the virus-host interactions are incompletely known, especially in the deep sea. Here we report on their distributions and relationships with environmental factors at 21 stations covering a latitudinal range (2-23(o) N) in the Western Pacific Ocean. This region is characterized by a complex western boundary current system. Synechococcus, autotrophic picoeukaryotes, heterotrophic prokaryotes and virus-like particles (VLPs) were high (<2...
December 2, 2016: FEMS Microbiology Ecology
https://www.readbyqxmd.com/read/27901493/has-aidi-injection-the-attenuation-and-synergistic-efficacy-to-gemcitabine-and-cisplatin-in-non-small-cell-lung-cancer-a-meta-analysis-of-36-randomized-controlled-trials
#2
Zheng Xiao, Chengqiong Wang, Ling Chen, Xuemei Tang, Lianhong Li, Nana Li, Jing Li, Qihai Gong, Fushan Tang, Jihong Feng, Xiaofei Li
Gemcitabine and cisplatin is the first line chemotherapy for non-small cell lung cancer with high toxicity. Aidi injection is a cantharidin and astragalu-based Chinese herbs injection in China. Has Aidi injection attenuation and synergistic efficacy to GP in NSCLC? There is lack of strong evidence to prove it. To further reveal it, we systematically evaluated all related studies. We collected all studies about Aidi injection plus GP for NSCLC in Medline, Embase, Web of Science, CNKI, VIP, Wanfang Database, CBM, CCRCT, Chi-CTR, and US-clinical trials (established to June 2015)...
November 25, 2016: Oncotarget
https://www.readbyqxmd.com/read/27888163/antimicrobial-photodynamic-therapy-adjuvant-to-non-surgical-periodontal-therapy-in-patients-with-diabetes-mellitus-a-meta-analysis
#3
REVIEW
Tariq Abduljabbar, Fahim Vohra, Fawad Javed, Zohaib Akram
BACKGROUND: To determine whether treatment with antimicrobial photodynamic therapy (aPDT) as an adjunct to scaling and root planing (SRP) improves periodontal clinical and glycemic outcomes in chronic periodontitis patients (CP) with type 2 diabetes mellitus (DM). METHODS: Databases (MEDLINE via PubMed; EMBASE; Cochrane Central Register of Controlled Trials and Cochrane Oral Health Group Trials Register databases) were searched up to and including October 2016. The addressed PICO question was: "What are the effects aPDT as an adjunct to SRP in terms of periodontal and glycemic outcomes as compared to SRP alone in individuals with DM?" RESULTS: Four randomized clinical trials were included in the present review...
November 22, 2016: Photodiagnosis and Photodynamic Therapy
https://www.readbyqxmd.com/read/27888049/overdenture-prosthesis-retained-by-mini-dental-implants-a-systematic-review
#4
REVIEW
Cleidiel Aparecido Araujo Lemos, Fellippo Ramos Verri, Victor Eduardo de Souza Batista, Joel Ferreira Santiago Júnior, Caroline Cantieri Mello, Eduardo Piza Pellizzer
OBJECTIVE: The purpose of this systematic review was to evaluate the influence of mini implants to retain overdenture prosthesis in terms of survival rates of mini implants, marginal bone loss, satisfaction, and quality of life. DATA: This report followed the PRISMA Statement and PICO question. This review has been registered at PROSPERO under the number CRD42016036141. SOURCE: Two independent reviewers performed a comprehensive search of studies published until September 2016 and listed in the PubMed/MEDLINE, Embase, and The Cochrane Library databases...
November 22, 2016: Journal of Dentistry
https://www.readbyqxmd.com/read/27886101/fatty-acid-and-phenolic-compound-concentrations-in-eight-different-monovarietal-virgin-olive-oils-from-extremadura-and-the-relationship-with-oxidative-stability
#5
Alfonso Montaño, Marcos Hernández, Inmaculada Garrido, José Luís Llerena, Francisco Espinosa
Olive oils have been shown to be more resistant to oxidation than other vegetable fats, mainly due to their fatty acid (FA) profile which is rich in oleic acid and to their high content of antioxidants, principally phenols and tocopherols. This has situated virgin olive oils (VOOs) among the fats of high nutritional quality. However, it is important to stress that the oil's commercial category (olive oil, virgin olive oil, extra-virgin olive oil), the variety of the source plant, and the extraction-conservation systems all decisively influence the concentration of these antioxidants and the oil's shelf-life...
November 23, 2016: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/27885878/a-systematic-review-of-risks-and-benefits-with-nipple-areola-reconstruction
#6
Camilla Morken Kristoffersen, Håvard Seland, Emma Hansson
BACKGROUND: Most women who have their breast reconstructed are offered NAC reconstruction. Nonetheless, it is unclear what scientific evidence there is for the procedure. The aims of the present systematic review were to evaluate the quality of evidence for benefits and risks with NAC reconstruction, and to examine the evidence for different techniques. METHODS: Relevant databases were searched. Inclusion criteria were controlled studies comprising ≥20 patients and a case series of ≥50 patients...
November 25, 2016: Journal of Plastic Surgery and Hand Surgery
https://www.readbyqxmd.com/read/27882643/micelles-bicelles-and-nanodiscs-comparing-the-impact-of-membrane-mimetics-on-membrane-protein-backbone-dynamics
#7
Lukas Frey, Nils-Alexander Lakomek, Roland Riek, Stefan Bibow
Detergents are often used to investigate the structure and dynamics of membrane proteins. Whereas the structural integrity seems to be preserved in detergents for many membrane proteins, their functional activity is frequently compromised, but can be restored in a lipid environment. Herein we show with per-residue resolution that while OmpX forms a stable β-barrel in DPC detergent micelles, DHPC/DMPC bicelles, and DMPC nanodiscs, the pico- to nanosecond and micro- to millisecond motions differ substantially between the detergent and lipid environment...
November 24, 2016: Angewandte Chemie
https://www.readbyqxmd.com/read/27881317/an-update-on-computer-engineered-complete-dentures-a-systematic-review-on-clinical-outcomes
#8
REVIEW
Mathew T Kattadiyil, Abdulaziz AlHelal
STATEMENT OF PROBLEM: Reports on computer-engineered complete dentures (CECDs) continue to increase. Systematic reviews on clinical outcomes and applications associated with CECDs are lacking in the literature. PURPOSE: The purpose of this systematic review was to determine the clinical outcomes and applications of CECDs. MATERIAL AND METHODS: Electronic searches of the English literature from January 1984 to May 2016 were performed in MEDLINE and Cochrane databases, with the results enriched by hand searches and citation mining to address 2 relevant population intervention comparison outcome (PICO) questions: What are the clinical outcomes associated with CECDs? Are there specific applications and significant advantages for CECDs? RESULTS: A review of the selected articles on CECDs revealed significantly better retention and reduced clinical time for the milled CECDs compared with conventional complete dentures...
October 27, 2016: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/27878810/improvement-of-phytoplankton-culture-isolation-using-single-cell-sorting-by-flow-cytometry
#9
Dominique Marie, Florence Le Gall, Roseline Edern, Priscillia Gourvil, Daniel Vaulot
Flow cytometry provides a tool to physically sort single algal cells in order to obtain clonal cultures. During sorting, cells are submitted to physical stress factors such as high fluidic pressure, exposure to the laser beam, electrostatic charges, deflection through high voltage fields and collisions with container surfaces. All of these can damage the cells of interest and success rates for initiation of cultures from flow-sorted cells are generally very low. We found that the addition of Bovine Serum Albumin (BSA) in the culture medium into which cells are sorted drastically improved the success of initiation of pico- and nano-eukaryotic phytoplankton strains...
November 22, 2016: Journal of Phycology
https://www.readbyqxmd.com/read/27876507/exercise-induced-cytokine-changes-in-antigen-stimulated-whole-blood-cultures-compared-to-serum
#10
C Pilat, K Krüger, T Frech, F C Mooren
Strenuous exercise is followed by an elevation of many cytokines with inflammation regulating properties. Since most cytokines act at pico- or nanomolar concentrations many investigations failed to detect their concentrations in vivo. Hence, the aim of this study was to evaluate the significance of cytokine measurements (IL-1β, TNF-α, IL-1ra, IL-6, CCL2 and CXCL8) in a stimulated whole-blood culture (sWBC) compared to serum with respect to their exercise-induced kinetics and detection rates. 40 male volunteers (age: 25,5 ± 4,3 years, BMI: 24,00 ± 2,24, VO2peak: 46,9 ± 4,1 ml/kg x min) performed 60 minutes of intensive bicycle exercise (80% VO2peak)...
November 19, 2016: Journal of Immunological Methods
https://www.readbyqxmd.com/read/27875942/a-combined-study-of-meg-and-pico-tesla-tms-on-children-with-autism-disorder
#11
Photios Anninos, Athanasios Chatzimichael, Adam Adamopoulos, Athanasia Kotini, Nicolaos Tsagas
Magnetoencephalographic (MEG) recordings from the brain of 10 children with autism (6 boys and 4 girls, with ages range from 5-12 years, mean[Formula: see text][Formula: see text][Formula: see text]SD: 8.3[Formula: see text][Formula: see text][Formula: see text]2.1) were obtained using a whole-head 122-channel MEG system in a magnetically shielded room of low magnetic noise. A double-blind experimental design was used in order to look for possible effect of external pico-Tesla Transcranial Magnetic Stimulation (pT-TMS)...
November 23, 2016: Journal of Integrative Neuroscience
https://www.readbyqxmd.com/read/27875326/modeling-hybrid-perovskites-by-molecular-dynamics
#12
Alessandro Mattoni, Alessio Filippetti, Claudia Caddeo
The topical review describes the recent progress in the modeling of hybrid perovskites by molecular dynamics simulations. Hybrid perovskites and in particular methylammonium lead halide (MAPI) have a tremendous technological relevance representing the fastest-advancing solar material to date. They also represent the paradigm of an organic-inorganic crystalline material with some conceptual peculiarities: an inorganic semiconductor for what concerns the electronic and absorption properties with a hybrid and solution processable organic-inorganic body...
November 22, 2016: Journal of Physics. Condensed Matter: An Institute of Physics Journal
https://www.readbyqxmd.com/read/27874268/a-combination-of-resveratrol-and-quercetin-induces-browning-in-white-adipose-tissue-of-rats-fed-an-obesogenic-diet
#13
Noemí Arias, Catalina Picó, M Teresa Macarulla, Paula Oliver, Jonatan Miranda, Andreu Palou, María P Portillo
OBJECTIVE: To analyze whether a combination of quercetin (Q) and resveratrol (RSV) would induce a white adipose tissue (WAT) browning effect. METHODS: Thirty-six rats were fed an obesogenic diet and divided into four groups: control, treated with RSV (15 mg/kg body weight/day; RSV group), treated with Q (30 mg/kg body weight/day; Q group), or treated with both polyphenols (RSV + Q group). RESULTS: After 6 weeks, body and WAT weights were significantly reduced in the RSV + Q group...
November 22, 2016: Obesity
https://www.readbyqxmd.com/read/27870921/microthreaded-implants-and-crestal-bone-loss-a-systematic-review
#14
Ahmad Al-Thobity, Ahmad Kutkut, Khalid Almas
This systematic literature review investigated the effect of microthreaded-neck dental implants on crestal bone loss. Using the participants, interventions, comparison groups, outcomes, and study design (PICOS) system, we addressed the following focused question: Do microthreaded-neck dental implants positively affect the crestal bone level around dental implants? We searched 3 electronic databases to find articles published between January 1995 and June 2016 that contained any combination of the following keywords: dental implant, microthread, microthreaded, crestal bone level, crestal bone loss, and alveolar bone level...
November 21, 2016: Journal of Oral Implantology
https://www.readbyqxmd.com/read/27867760/pico-and-nanoplankton-abundance-and-carbon-stocks-along-the-brazilian-bight
#15
Catherine Gérikas Ribeiro, Adriana Lopes Dos Santos, Dominique Marie, Vivian Helena Pellizari, Frederico Pereira Brandini, Daniel Vaulot
Pico and nanoplankton communities from the Southwest Atlantic Ocean along the Brazilian Bight are poorly described. The hydrography in this region is dominated by a complex system of layered water masses, which includes the warm and oligotrophic Tropical Water (TW), the cold and nutrient rich South Atlantic Central Water (SACW) and the Coastal Water (CW), which have highly variable properties. In order to assess how pico- and nanoplankton communities are distributed in these different water masses, we determined by flow cytometry the abundance of heterotrophic bacteria, Prochlorococcus, Synechococcus and autotrophic pico and nanoeukaryotes along three transects, extending from 23°S to 31°S and 39°W to 49°W...
2016: PeerJ
https://www.readbyqxmd.com/read/27858581/evidence-based-guidelines-for-fatigue-risk-management-in-ems-formulating-research-questions-and-selecting-outcomes
#16
P Daniel Patterson, J Stephen Higgins, Eddy S Lang, Michael S Runyon, Laura K Barger, Jonathan R Studnek, Charity G Moore, Kathy Robinson, Dia Gainor, Allison Infinger, Patricia M Weiss, Denisse J Sequeira, Christian Martin-Gill
BACKGROUND: Greater than half of Emergency Medical Services (EMS) personnel report work-related fatigue, yet there are no guidelines for the management of fatigue in EMS. A novel process has been established for evidence-based guideline (EBG) development germane to clinical EMS questions. This process has not yet been applied to operational EMS questions like fatigue risk management. The objective of this study was to develop content valid research questions in the Population, Intervention, Comparison, and Outcome (PICO) framework, and select outcomes to guide systematic reviews and development of EBGs for EMS fatigue risk management...
November 18, 2016: Prehospital Emergency Care
https://www.readbyqxmd.com/read/27846446/studies-in-using-a-universal-exchange-and-inference-language-for-evidence-based-medicine-semi-automated-learning-and-reasoning-for-pico-methodology-systematic-review-and-environmental-epidemiology
#17
Barry Robson
The Q-UEL language of XML-like tags and the associated software applications are providing a valuable toolkit for Evidence Based Medicine (EBM). In this paper the already existing applications, data bases, and tags are brought together with new ones. The particular Q-UEL embodiment used here is the BioIngine. The main challenge is one of bringing together the methods of symbolic reasoning and calculative probabilistic inference that underlie EBM and medical decision making. Some space is taken to review this background...
October 17, 2016: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/27828636/indication-guidelines-for-mohs-micrographic-surgery-in-skin-tumors
#18
Selma Schuartz Cernea, Gabriel Gontijo, Eugenio Raul de Almeida Pimentel, Roberto Gomes Tarlé, Glaysson Tassara, Juliana Areas de Souza Lima Beltrame Ferreira, Victor Miguel Coutinho Fernandes, Wanderley Marques Bernardo
Mohs micrographic surgery is a technique used to excise skin tumors based on comprehensive surgical mapping, in which the surgeon removes the tumor, followed by a complete histological evaluation of the tumor's margins. The correlation of the presence of a tumor in histological examinations and its precise location on the surgical map result in a complete removal of the tumor with maximum normal tissue preservation. The present article seeks to provide general practitioners and healthcare specialists with guidelines regarding recommendations for Mohs micrographic surgery to treat skin tumors, based on the most reliable evidence available in medical literature on the subject...
September 2016: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/27827917/analytical-study-on-multi-tier-5g-heterogeneous-small-cell-networks-coverage-performance-and-energy-efficiency
#19
Zhu Xiao, Hongjing Liu, Vincent Havyarimana, Tong Li, Dong Wang
In this paper, we investigate the coverage performance and energy efficiency of multi-tier heterogeneous cellular networks (HetNets) which are composed of macrocells and different types of small cells, i.e., picocells and femtocells. By virtue of stochastic geometry tools, we model the multi-tier HetNets based on a Poisson point process (PPP) and analyze the Signal to Interference Ratio (SIR) via studying the cumulative interference from pico-tier and femto-tier. We then derive the analytical expressions of coverage probabilities in order to evaluate coverage performance in different tiers and investigate how it varies with the small cells' deployment density...
November 4, 2016: Sensors
https://www.readbyqxmd.com/read/27818898/identification-of-a-novel-parallel-%C3%AE-strand-conformation-within-molecular-monolayer-of-amyloid-peptide
#20
Lei Liu, Qiang Li, Shuai Zhang, Xiaofeng Wang, Søren Vrønning Hoffmann, Jingyuan Li, Zheng Liu, Flemming Besenbacher, Mingdong Dong
The differentiation of protein properties and biological functions arises from the variation in the primary and secondary structure. Specifically, in abnormal assemblies of protein, such as amyloid peptide, the secondary structure is closely correlated with the stable ensemble and the cytotoxicity. In this work, the early Aβ33-42 aggregates forming the molecular monolayer at hydrophobic interface are investigated. The molecular monolayer of amyloid peptide Aβ33-42 consisting of novel parallel β-strand-like structure is further revealed by means of a quantitative nanomechanical spectroscopy technique with force controlled in pico-Newton range, combining with molecular dynamic simulation...
June 2016: Advanced Science (Weinheim, Baden-Wurttemberg, Germany)
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