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https://www.readbyqxmd.com/read/29330655/effectiveness-for-dentin-hypersensitivity-treatment-of-non-carious-cervical-lesions-a-meta-analysis
#1
REVIEW
Vittorio Moraschini, Larissa Salina da Costa, Gustavo Oliveira Dos Santos
OBJECTIVE: The aim of this review is to conduct a systematic review and meta-analysis comparing the effectiveness of in-home or in-office treatments for dentin hypersensitivity. MATERIALS AND METHODS: An electronic search without restriction on dates or languages was performed in four electronic databases until March 2017. In addition, hand-searches in regular journals and in the gray literature were also conducted. To develop the search strategy, clinical questions were formulated using the PICOS method...
January 12, 2018: Clinical Oral Investigations
https://www.readbyqxmd.com/read/29327015/a-water-soluble-bay-functionalized-perylenediimide-derivative-correlating-aggregation-and-excited-state-dynamics
#2
K Dirian, S Bauroth, A Roth, Z Syrgiannis, F Rigodanza, M Burian, H Amenitsch, D I Sharapa, M Prato, T Clark, D M Guldi
The aggregation and the photophysics of a water soluble perylenediimide (PDI) derivative that features two bromine substituents in the bay positions has been probed. Non-fluorescent aggregates were found to be present at concentrations of 1.0 × 10-5 M. In situ small-angle X-ray scattering (SAXS) measurements and complementary molecular modeling showed the presence of PDI aggregates. In their singlet excited states, the PDI aggregates are characterized by distinct transient fingerprints and rapid deactivation, as revealed by pump-probe experiments on the femto-, pico-, nano-, and microsecond timescales...
January 12, 2018: Nanoscale
https://www.readbyqxmd.com/read/29324069/evidence-based-guidelines-for-fatigue-risk-management-in-emergency-medical-services
#3
P Daniel Patterson, J Stephen Higgins, Hans P A Van Dongen, Daniel J Buysse, Ronald W Thackery, Douglas F Kupas, David S Becker, Bradley E Dean, George H Lindbeck, Francis X Guyette, Josef H Penner, John M Violanti, Eddy S Lang, Christian Martin-Gill
BACKGROUND: Administrators of Emergency Medical Services (EMS) operations lack guidance on how to mitigate workplace fatigue, which affects greater than half of all EMS personnel. The primary objective of the Fatigue in EMS Project was to create an evidence-based guideline for fatigue risk management tailored to EMS operations. METHODS: Systematic searches were conducted from 1980 to September 2016 and guided by seven research questions framed in the Population, Intervention, Comparison, Outcome (PICO) framework...
January 11, 2018: Prehospital Emergency Care
https://www.readbyqxmd.com/read/29324053/systematic-review-methodology-for-the-fatigue-in-emergency-medical-services-project
#4
P Daniel Patterson, J Stephen Higgins, Patricia M Weiss, Eddy Lang, Christian Martin-Gill
BACKGROUND: Guidance for managing fatigue in the Emergency Medical Services (EMS) setting is limited. The Fatigue in EMS Project sought to complete multiple systematic reviews guided by seven explicit research questions, assemble the best available evidence, and rate the quality of that evidence for purposes of producing an Evidence Based Guideline (EBG) for fatigue risk management in EMS operations. METHODS: We completed seven systematic reviews that involved searches of six databases for literature relevant to seven research questions...
January 11, 2018: Prehospital Emergency Care
https://www.readbyqxmd.com/read/29308293/a-neural-candidate-selector-architecture-for-automatic-structured-clinical-text-annotation
#5
Gaurav Singh, Iain J Marshall, James Thomas, John Shawe-Taylor, Byron C Wallace
We consider the task of automatically annotating free texts describing clinical trials with concepts from a controlled, structured medical vocabulary. Specifically we aim to build a model to infer distinct sets of (ontological) concepts describing complementary clinically salient aspects of the underlying trials: the populations enrolled, the interventions administered and the outcomes measured, i.e., the PICO elements. This important practical problem poses a few key challenges. One issue is that the output space is vast, because the vocabulary comprises many unique concepts...
November 2017: Proceedings of the ... ACM International Conference on Information & Knowledge Management
https://www.readbyqxmd.com/read/29302176/no-more-broken-promises-challenges-and-opportunities-for-key-populations-in-demanding-more-transparency-accountability-and-participation-in-the-global-response-against-the-hiv-and-aids-epidemic
#6
Tomás A Chang Pico, Jillian Clare Kohler, Julia Hoffmann, Lucy Mungala
The global fight against HIV/AIDS continues to pose challenges: infection rates are on the rise in many settings, stigma and discrimination remain rampant, and the global response is under increasing financial pressure. There is a high risk of losing what has been achieved so far in the fight against HIV and AIDS, but also the momentum to meet the so-called Fast Track targets for 2030. In light of these trends, it is fundamental to focus on the human rights of key populations (KPs)-especially to health, non-discrimination, access to information, and to equal and meaningful participation in political and public affairs-by placing them at the center of the global HIV response...
December 2017: Health and Human Rights
https://www.readbyqxmd.com/read/29289303/determination-of-ultra-trace-level-of-232th-in-seawater-by-icp-sfms-after-matrix-separation-and-preconcentration
#7
Irena Wysocka, Emilia Vassileva
This article describes the development and validation of an analytical procedure for the matrix separation, preconcentration and determination of sub-ng kg-1 levels 232Th in a small volume (20 mL) of seawater samples. The matrix separation and Th preconcentration was carried out using a commercially available ion-chelation system seaFAST-pico. The acidified to pH < 2 seawater samples were mixed on-line with the ammonium acetate buffer (pH of 6.0 ± 0.2) before loading on the column containing resin with iminodiacetic and ethylenediaminetriacetic functional groups...
February 13, 2018: Analytica Chimica Acta
https://www.readbyqxmd.com/read/29289004/parallel-assessment-of-marine-autotrophic-picoplankton-using-flow-cytometry-and-chemotaxonomy
#8
Marju Tamm, Peeter Laas, Rene Freiberg, Peeter Nõges, Tiina Nõges
Autotrophic picoplankton (0.2-2μm) can be a significant contributor to primary production and hence play an important role in carbon flow. The phytoplankton community structure in the Baltic Sea is very region specific and the understanding of the composition and dynamics of pico-size phytoplankton is generally poor. The main objective of this study was to determine the contribution of picoeukaryotic algae and their taxonomic composition in late summer phytoplankton community of the West-Estonian Archipelago Sea...
December 27, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29286329/amyloid-biomarkers-in-conformational-diseases-at-face-value-a-systematic-review
#9
REVIEW
Maria Fernanda Avila-Vazquez, Nelly F Altamirano-Bustamante, Myriam M Altamirano-Bustamante
Conformational diseases represent a new aspect of proteomic medicine where diagnostic and therapeutic paradigms are evolving. In this context, the early biomarkers for target cell failure (neurons, β-cells, etc.) represent a challenge to translational medicine and play a multidimensional role as biomarkers and potential therapeutic targets. This systematic review, which follows the PICO and Prisma methods, analyses this new-fangled multidimensionality, its strengths and limitations, and presents the future possibilities it opens up...
December 29, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29285645/analysis-of-ibuprofen-and-its-main-metabolites-in-roots-shoots-and-seeds-of-cowpea-vigna-unguiculata-l-walp-using-liquid-chromatography-quadrupole-time-of-flight-mass-spectrometry-uptake-metabolism-and-translocation
#10
Yolanda Picó, Rodrigo Alvarez-Ruiz, Leonard Wijaya, Ahmed Alfarhan, Mohammed Alyemeni, Damià Barceló
A liquid chromatography quadruple time-of-flight mass spectrometry (LC-QqTOF-MS/MS) method was developed for simultaneous quantitative analysis of ibuprofen (IBU), 1- and 2-hydroxyibuprofen (1-OH IBU and 2-OH IBU), and carboxyibuprofen (CBX IBU) while preserving the ability of the instrument to get precursor and product ion mass spectra of non-target compounds. The trigger was the precursor ions reaching 100 cps intensity. Sample preparation was carried out by ultrasound solid-liquid extraction with methanol as extraction solvent at pH < 2 followed by solid-phase extraction (SPE) clean-up using STRATA-X cartridges and methanol as an eluent...
December 29, 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/29281866/comparative-diagnostic-performance-of-ultrasonography-and-99mtc-sestamibi-scintigraphy-for-parathyroid-adenoma-in-primary-hyperparathyroidism-systematic-review-and-meta-analysis
#11
Reza Nafisi Moghadam, Amir Pasha Amlelshahbaz, Nasim Namiranian, Mohammad Sobhan-Ardekani, Mahmood Emami-Meybodi, Ali Dehghan, Masoud Rahmanian, Seid Kazem Razavi-Ratki
Objective: Ultrasonography (US) and parathyroid scintigraphy (PS) with 99mTc-MIBI are common methods for preoperative localization of parathyroid adenomas but there discrepancies exist with regard to diagnostic accuracy. The aim of the study was to compare PS and US for localization of parathyroid adenoma with a systematic review and meta-analysis of the literature. Methods: Pub Med, Scopus (EMbase), Web of Science and the reference lists of all included studies were searched up to 1st January 2016. The search strategy was according PICO characteristics...
December 28, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/29281069/effectiveness-of-behavioral-interventions-to-reduce-the-intake-of-sugar-sweetened-beverages-in-children-and-adolescents-a-systematic-review-and-meta-analysis
#12
Abir Abdel Rahman, Lamis Jomaa, Lara A Kahale, Pauline Adair, Cynthia Pine
Context: Consumption of sugar-sweetened beverages (SSBs) among children has been associated with adverse health outcomes. Numerous behavioral interventions aimed at reducing the intake of SSBs among children have been reported, yet evidence of their effectiveness is lacking. Objective: This systematic review explored the effectiveness of educational and behavioral interventions to reduce SSB intake and to influence health outcomes among children aged 4 to 16 years...
December 21, 2017: Nutrition Reviews
https://www.readbyqxmd.com/read/29278371/flavonoids-and-phenolic-acids-from-oregano-occurrence-biological-activity-and-health-benefits
#13
REVIEW
Erick P Gutiérrez-Grijalva, Manuel A Picos-Salas, Nayely Leyva-López, Marilyn S Criollo-Mendoza, Gabriela Vazquez-Olivo, J Basilio Heredia
Several herb species classified as oregano have been widely used in folk medicine to alleviate inflammation-related diseases, respiratory and digestive disorders, headaches, rheumatism, diabetes and others. These potential health benefits are partially attributed to the phytochemical compounds in oregano such as flavonoids (FL) and phenolic acids (PA). Flavonoids and phenolic acids are among the most abundant and most studied phytochemicals in oregano species. Epidemiological, in vitro and in vivo experiments have related long-term consumption of dietary FL and PA with a decreased risk of incidence of chronic diseases...
December 26, 2017: Plants (Basel, Switzerland)
https://www.readbyqxmd.com/read/29278359/incomplete-penetrance-and-variable-expressivity-hallmarks-in-channelopathies-associated-with-sudden-cardiac-death
#14
REVIEW
Monica Coll, Alexandra Pérez-Serra, Jesus Mates, Bernat Del Olmo, Marta Puigmulé, Anna Fernandez-Falgueras, Anna Iglesias, Ferran Picó, Laura Lopez, Ramon Brugada, Oscar Campuzano
Sudden cardiac death is defined as an unexpected decease of cardiac origin. In individuals under 35 years old, most of these deaths are due to familial arrhythmogenic syndromes of genetic origin, also known as channelopathies. These familial cardiac syndromes commonly follow an autosomal dominant pattern of inheritance. Diagnosis, however, can be difficult, mainly due to incomplete penetrance and variable expressivity, which are hallmarks in these syndromes. The clinical manifestation of these diseases can range from asymptomatic to syncope but sudden death can sometimes be the first symptom of disease...
December 26, 2017: Biology
https://www.readbyqxmd.com/read/29276544/analysis-of-agreement-between-expired-air-carbon-monoxide-monitors
#15
Joshua L Karelitz, Valerie C Michael, Kenneth A Perkins
Introduction: The current study examined the level of agreement in expired-air carbon monoxide (CO) values, focusing especially on those confirming abstinence, between the two most commonly used CO monitors, the Vitalograph BreathCO and the Bedfont piCO+ Smokerlyzer. Methods: Expired-air samples were collected via both monitors from adult dependent smokers (44 M, 34 F) participating in studies using CO values to confirm abstinence durations of: 24 hours, 12 hours, or no abstinence...
June 2017: Journal of Smoking Cessation
https://www.readbyqxmd.com/read/29274156/autogenous-teeth-used-for-bone-grafting-a-systematic-review
#16
P Gual-Vaques, C Polis-Yanes, A Estrugo-Devesa, R Ayuso-Montero, A Mari-Roig, J Lopez-Lopez
BACKGROUND: Recently, bone graft materials using permanent teeth have come to light, and clinical and histological outcomes of this material have been confirmed by some studies. The aim of this systematic review was to evaluate the reliability of the autogenous tooth bone graft material applied to alveolar ridge augmentation procedures. MATERIAL AND METHODS: A systematic review of literature was conducted analyzing articles published between 2007 and 2017. The following four outcome variables were defined: a) implant stability b) post-operative complication c) evaluation of implant survival and failure rates, and d) histological analysis...
December 23, 2017: Medicina Oral, Patología Oral y Cirugía Bucal
https://www.readbyqxmd.com/read/29261713/targeted-next-generation-sequencing-provides-novel-clues-for-associated-epilepsy-and-cardiac-conduction-disorder-sudep
#17
Monica Coll, Pasquale Striano, Carles Ferrer-Costa, Oscar Campuzano, Jesús Matés, Bernat Del Olmo, Anna Iglesias, Alexandra Pérez-Serra, Irene Mademont, Ferran Picó, Antonio Oliva, Ramon Brugada
Sudden unexpected death in epilepsy is an unpredicted condition in patients with a diagnosis of epilepsy, and autopsy does not conclusively identify cause of death. Although the pathophysiological mechanisms that underlie this entity remain unknown, the fact that epilepsy can affect cardiac function is not surprising. The genetic factors involving ion channels co-expressed in the heart and brain and other candidate genes have been previously described. In the present study, 20 epilepsy patients with personal or family history of heart rhythm disturbance/cardiac arrhythmias/sudden death were sequenced using a custom re-sequencing panel...
2017: PloS One
https://www.readbyqxmd.com/read/29260837/the-challenges-of-describing-rehabilitation-services-a-discussion-paper
#18
Cecilie Røe, Marit Kirkevold, Nada Andelic, Helene L Soberg, Unni Sveen, Erik Bautz-Holter, Reidun Jahnsen, Marleen R van Walsem, Line Kildal Bragstad, Ellen Gabrielsen Hjelle, Gunvor Klevberg, Per Oretorp, Andreas Habberstad, Jon Hagfors, Randi Væhle, Grace Engen, Christoph Gutenbrunner
To apply the Classification of Service Organization in Rehabilitation (ICSO-R) classification of services to different target groups, include the user perspective, identify missing categories, and propose standardized descriptors for the categories from a Norwegian perspective. Expert-based consensus conferences with user involvement. Health professionals, stakeholders and users. Participants were divided into 5 panels, which applied the ICSO-R to describe the habilitation and rehabilitation services provided to children with cerebral palsy and people with Huntington's disease, acquired brain injuries (traumatic brain injuries and stroke) and painful musculoskeletal conditions...
December 20, 2017: Journal of Rehabilitation Medicine
https://www.readbyqxmd.com/read/29251448/how-helpful-are-mnemonics-in-the-development-of-a-research-question
#19
Helen Sisson
BACKGROUND: The formulation of a research question is a vital first step in the research process and the significance of this is well reported in the literature; a well-structured question increases the outcome of useable findings. To aid the development of a research question, a number of frameworks in the form of mnemonics have been identified. It is suggested that the application of these mnemonics may result in confusion rather than provide helpful guidance. AIM: To present an overview of some of the mnemonically identified frameworks and consider how they may support the development of a research question...
December 18, 2017: Nurse Researcher
https://www.readbyqxmd.com/read/29248330/sect-clinical-practice-guideline-on-the-management-of-patients-with-spontaneous-pneumothorax
#20
Borja Aguinagalde, José Luis Aranda, Pablo Busca, Ivan Martínez, Iñigo Royo, Jon Zabaleta
This clinical practice guideline (CPG) emerges as an initiative of the scientific committee of the Spanish Society of Thoracic Surgery. We formulated PICO (patient, intervention, comparison, and outcome) questions on various aspects of spontaneous pneumothorax. For the evaluation of the quality of evidence and preparation of recommendations we followed the guidelines of the Grading of recommendations, Assessment, Development and Evaluation (GRADE) working group.
December 13, 2017: Cirugía Española
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