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https://www.readbyqxmd.com/read/29456940/mrmc-neo-surgical-ventilating-port-and-neo-attic-malleo-incudal-complex-in-endoscopic-management-of-limited-attico-antral-cholesteatoma
#1
C B Nandyal, Mithun Sutrave, Vinayak Kurle, Pallavi A Harsoor
To study functional outcome of the endoscopic management of limited attico-antral cholesteatoma in terms of visualization of sac, cholesteatoma disease clearance, ABG closure improvement, preservation of residual anatomy and recurrence of disease. It is a prospective study done during Feb 2016 to March 2017 done on 20 pts with limited attico-antral cholesteatoma with CT confirmation. Endoscopic management of limited attico-antral cholesteatoma with complete removal of sac, infected discharge and granulations along with creation of MRMC Neo surgical ventilating port (joining Anterior & posterior isthmuses) done in cases where residual attic anatomy was present to establish physiological attic ventilation and drainage...
March 2018: Indian Journal of Otolaryngology and Head and Neck Surgery
https://www.readbyqxmd.com/read/29446987/dexmedetomidine-decreases-postoperative-pain-and-narcotic-use-in-children-undergoing-alveolar-bone-graft-surgery
#2
Mariela M Lopez, Derrick Zech, Judith L Linton, Steven J Blackwell
OBJECTIVE: Dexmedetomidine is a parenteral agent that combines the benefits of cooperative sedation, anxiolysis, and analgesia without the risks of respiratory depression. Off-label use has been reported in children. We have introduced dexmedetomidine for use in patients having undergone alveolar bone graft (ABG). The objective is to demonstrate the value and safety of postoperative dexmedetomidine infusion in a non-ICU setting following ABG. DESIGN: A retrospective review was performed on patients who underwent ABG by the senior author...
January 1, 2018: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/29437516/ideal-versus-late-secondary-alveolar-bone-graft-surgery-a-bone-thickness-cone-beam-computed-tomographic-assessment
#3
Michele Alves Garcia, Marilia Yatabe, Thais Ustulin Fuzer, Adriana Maria Calvo, Ivy Kiemle Trindade-Suedam
OBJECTIVE: To compare the bone morphology after secondary alveolar bone graft surgery (SABG) performed before and after permanent canine eruption. DESIGN: Cross-sectional study. SETTING: Hospital for Rehabilitation of Craniofacial Anomalies, University of São Paulo, Bauru, SP, Brazil. PATIENTS: 25 cone-beam computed tomography (CBCT) scans of complete unilateral cleft lip and palate (CLP) individuals who underwent SABG before or after eruption of the permanent canine taken 2 and 6 months (T1 and T2) after SAGB, resulting in 50 CBCT scans...
March 2018: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/29422731/role-of-correction-factor-in-minimizing-errors-while-calculating-electrolyte-values-between-blood-gas-analyzer-and-laboratory-autoanalyzer-a-comparative-study
#4
Abhinav Banerjee, Gesu Mehrotra
Aims: Electrolytes are charged elements that play important functions in the body. They are measured by both arterial blood-gas (ABG) analyzers and autoanalyzers (AA). In this study, we tried to find out the correction factor for sodium and potassium to establish the concordance between ABG and AA values. Materials and Methods: We prospectively studied 100 samples of patients, and for validation of the result, we applied our result on 30 patients later. 1.5 ml of blood collected in the 2...
January 2018: Indian Journal of Critical Care Medicine
https://www.readbyqxmd.com/read/29397250/endoscopic-cartilage-versus-temporalis-fascia-grafting-for-anterior-quadrant-tympanic-perforations-a-prospective-study-in-a-tertiary-care-hospital
#5
Sanjeev Mohanty, Vinoth Manimaran, Preethi Umamaheswaran, Shivapriya Jeyabalakrishnan, Sreenivas Chelladurai
OBJECTIVE: Management of anterior perforations of tympanic membrane is a surgical challenge. The objective of this study is to analyse and compare the results of composite cartilage perichondrium island (CCPI) graft and temporalis fascia graft by endoscopic technique in anterior quadrant perforations. METHODS: A prospective study was conducted in a tertiary care centre from 2012-16. A total of 187 ear drums(n) in 168 patients with perforations involving anterior quadrant were included in the study...
January 31, 2018: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/29389246/increasing-cerebral-blood-flow-reduces-the-severity-of-central-sleep-apnea-at-high-altitude
#6
Keith R Burgess, Samuel J E Lucas, Katie Me Burgess, Kate E Sprecher, Joseph Donnelly, Aparna S Basnet, Michael M Tymko, Trevor A Day, Kurt Jason Smith, Nia C S Lewis, Philip Ainslie
Earlier studies have indicated an important role for cerebral blood flow in the pathophysiology of central sleep apnea (CSA) at high altitude, but were not decisive. To test the hypothesis that pharmacologically altering cerebral blood flow (CBF) without altering arterial blood gas (ABGs) values would alter the severity of CSA at high altitude, we studied 11 healthy volunteers. (8M, 3F; 31{plus minus}7 years) in a randomized placebo-controlled single-blind study at 5,050 metres in Nepal. CBF was increased by intravenous (iv) acetazolamide (Az; 10mg/kg) plus iv dobutamine (Dob) infusion (2-5 ug/kg/min) and reduced by oral indomethacin (Indo; 100mg)...
February 1, 2018: Journal of Applied Physiology
https://www.readbyqxmd.com/read/29355069/hearing-results-after-type-iii-tympanoplasty-incus-transpositionversus-porp-a-systematic-review
#7
Ricardo Bartel, Francesc Cruellas, Miriam Hamdan, Xavier Gonzalez-Compta, Enric Cisa, Ivan Domenech, Manel Manos
OBJECTIVE: The objective of this study is to compare hearing improvements in the air-bone gap (ABG) after type III tympanoplasties, comparing between incus transposition (IT) and partial ossicular replacement prosthesis (PORP). MATERIALS AND METHODS: Publications in English were searched in PUBMED database and were systematically reviewed. A total of 14 articles were included, obtaining 1055 patients, 614 for the IT group and 441 for the PORP group. Preoperative ABG, postoperative ABG, dB gain and ABG closure rate were compared...
January 21, 2018: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/29354672/impact-of-heated-humidified-high-flow-air-via-nasal-cannula-on-respiratory-effort-in-patients-with-chronic-obstructive-pulmonary-disease
#8
Charles W Atwood, Sharon Camhi, Kathryn C Little, Colleen Paul, Hobart Schweikert, Nicholas J Macmillan, Thomas L Miller
Background: High flow nasal cannula therapy (HFNC) has been widely adopted for respiratory distress, and evidence suggests that purging dead space of the upper airway improves gas fractions in the lung. This study tests the hypothesis that HFNC with room air could be as effective as low flow oxygen in chronic obstructive pulmonary disease (COPD). Methods: Thirty-two COPD patients prescribed 1 - 2 L/min of oxygen were studied. The conditions tested consisted of a control (CTRL; no therapy), then in random order HFNC and prescribed low flow oxygen (LFO)...
August 15, 2017: Chronic Obstructive Pulmonary Diseases: Journal of the COPD Foundation
https://www.readbyqxmd.com/read/29308831/anemia-hypoalbuminemia-and-elevated-troponin-levels-as-risk-factors-for-respiratory-failure-in-patients-with-severe-exacerbations-of-chronic-obstructive-pulmonary-disease-requiring-invasive-mechanical-ventilation
#9
Gordana Pavliša, Marina Labor, Hrvoje Puretić, Ana Hećimović, Marko Jakopović, Miroslav Samaržija
AIM: To determine in-hospital and post-discharge mortality, readmission rates, and predictors of invasive mechanical ventilation (IMV) in patients treated at intensive care unit (ICU) due to acute exacerbations of chronic obstructive pulmonary disease (AECOPD). METHODS: A retrospective observational cohort study included all patients treated at a respiratory ICU for AECOPD during one year. A total of 62 patients (41 men) with mean age 68.4±10.4 years were analyzed for outcomes including in-hospital and post-discharge mortality, readmission rates, and IMV...
December 31, 2017: Croatian Medical Journal
https://www.readbyqxmd.com/read/29284866/does-pulmonary-artery-systolic-pressure-as-estimated-by-transthoracic-echocardiography-alter-the-effect-of-positive-end-expiratory-pressure-on-arterial-blood-gases-and-hemodynamics-in-morbidly-obese-patients
#10
Dipti Saxena, Priyank Singh, Atul Dixit, Bipin Arya, Mohit Bhandari, Sadhana Sanwatsarkar
Background: Positive end-expiratory pressure (PEEP) at the time of induction increases oxygenation by preventing lung atelectasis. However, PEEP may not prove beneficial in all cases. Factors affecting the action of PEEP have not been elucidated well and remain controversial. Pulmonary vasculature has direct bearing on the action of PEEP as has been proven in the previous studies. Thus, this prospective study was planned to evaluate the action of PEEP on the basis of pulmonary artery systolic pressure (PASP) which is noninvasive and easily measured by transthoracic echocardiography...
October 2017: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/29258784/methemoglobinemia-in-a-case-of-paint-thinner-intoxication-treated-successfully-with-vitamin-c
#11
Deba Prasad Dhibar, Kamal Kant Sahu, Sanjay Jain, Savita Kumari, Subhash Chander Varma
BACKGROUND: Methemoglobin (MetHb) is an oxidized form of hemoglobin. It is a poor transporter of oxygen and is unable to deliver oxygen to the tissue. Globally, drug & toxin induced methemoglobinemia is more common as compared with the congenital form. Methemoglobinemia caused by paint thinner intoxication is rare. Methylene blue is well established as the first-line therapy for severe methemoglobinemia. CASE REPORT: A 25-year old man was brought to the Emergency Department after accidental consumption of paint thinner...
February 2018: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29238677/concept-importance-and-practice-of-lateral-tucking-in-tympanoplasty
#12
Sohil Vadiya
The current study aims at observing the technique and results of doing lateral tucking during tympanoplasty surgery. It is intended to provide additional support to the graft and prevent displacement as well. 98 cases included in the study and the graft uptake rate of 97.96% noted. Average pre operative air bone gap (ABG) was 31.12 db and average post operative ABG observed to be 14.01 db. Gain of 17.11 ± 7 db achieved by the procedure. Lateral tucking is a concept that requires to be inculcated in routine tympanoplasty surgeries, especially where canal skin incisions are used...
December 2017: Indian Journal of Otolaryngology and Head and Neck Surgery
https://www.readbyqxmd.com/read/29235879/experimental-studies-on-artifacts-and-tumor-enhancement-on-gadoxetic-acid-enhanced-arterial-phase-liver-mri-in-a-rabbit-vx2-tumor-model
#13
Takahiro Tsuboyama, Gregor Jost, Tonsok Kim, Masatoshi Hori, Hiromitsu Onishi, Hubertus Pietsch, Noriyuki Tomiyama
Background Rapid injection of gadoxetic acid is reported to produce more frequent artifacts and lower vascular enhancement on arterial phase liver magnetic resonance imaging (MRI). However, its effect on tumor enhancement and the mechanism of the artifacts remain unclear. Purpose To evaluate the effect of rapid injection of gadoxetic acid on artifacts and tumor enhancement during arterial phase liver MRI, and on arterial blood gases (ABGs) which may explain the cause of the artifacts. Material and Methods ABG analysis was performed in 13 free-breathing rabbits after rapid injection (1 mL/s; injection time = 0...
January 1, 2017: Acta Radiologica
https://www.readbyqxmd.com/read/29224257/models-of-care-for-non-invasive-ventilation-in-the-acute-copd-comparison-of-three-tertiary-hospitals-act3-study
#14
Kerry Parker, Vara Perikala, Ali Aminazad, Zheng Deng, Brigitte Borg, Catherine Buchan, Jo Toghill, Louis B Irving, Jeremy Goldin, David Charlesworth, Ajay Mahal, Suhith Illesinghe, Matthew T Naughton, Alan Young
BACKGROUND AND OBJECTIVE: Non-invasive ventilation (NIV) improves clinical outcomes in hypercapnic acute exacerbations of COPD (AECOPD), but the optimal model of care remains unknown. METHODS: We conducted a prospective observational non-inferiority study comparing three models of NIV care: general ward (Ward) (1:4 nurse to patient ratio, thrice weekly consultant ward round), a high dependency unit (HDU) (1:2 ratio, twice daily ward round) and an intensive care unit (ICU) (1:1 ratio, twice daily ward round) model in three similar teaching tertiary hospitals...
December 10, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/29210949/clinical-characteristics-and-treatment-outcomes-for-patients-with-external-auditory-canal-cholesteatoma
#15
Shinya Morita, Yuji Nakamaru, Atsushi Fukuda, Keishi Fujiwara, Kimiko Hoshino, Akihiro Homma
OBJECTIVE: We aimed to evaluate the clinical features and treatment outcomes for patients with idiopathic and secondary external auditory canal cholesteatoma (EACC), and to validate the treatment strategy from the perspective of hearing as well as etiology and staging. STUDY DESIGN: Retrospective case series. SETTING: Tertiary referral center and affiliated hospitals. PATIENTS: Fifty-eight patients with idiopathic EACC and 14 patients with secondary EACC...
November 28, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/29210947/toward-optimizing-cervical-vestibular-evoked-myogenic-potentials-cvemp-combining-air-bone-gap-and-cvemp-thresholds-to-improve-diagnosis-of-superior-canal-dehiscence
#16
Kimberley S Noij, Maria J Duarte, Kevin Wong, Y Song Cheng, Salwa Masud, Barbara S Herrmann, Hugh D Curtin, Vivek V Kanumuri, John J Guinan, Elliott D Kozin, Osama Tarabichi, David H Jung, Daniel J Lee, Steven D Rauch
OBJECTIVE: To develop a novel approach combining low-frequency air-bone gap (ABG) and cervical vestibular evoked myogenic potential (cVEMP) thresholds to improve screening for superior canal dehiscence (SCD) syndrome. STUDY DESIGN: Retrospective study. SETTING: Tertiary care center. PATIENTS: One hundred forty patients with SCD and 21 healthy age-matched controls were included. Ears for each patient were divided into three groups based on computed tomography (CT) findings: 1) dehiscent, 2) thin, or 3) unaffected...
November 28, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/29186488/a-putative-r3-myb-repressor-is-the-candidate-gene-underlying-atroviolacium-a-locus-for-anthocyanin-pigmentation-in-tomato-fruit
#17
Xue Cao, Zhengkun Qiu, Xiaotian Wang, Tong Van Giang, Xiaolin Liu, Jing Wang, Xiaoxuan Wang, Jianchang Gao, Yanmei Guo, Yongchen Du, Guoping Wang, Zejun Huang
Anthocyanins are potential health-promoting compounds in the human diet. The atv (atroviolacium) locus, derived from the wild tomato species Solanum cheesmaniae, has been shown to enhance anthocyanin pigmentation in tomato fruit when it co-exists with either the Aft (Anthocyanin fruit) or the Abg (Aubergine) locus. In the present study, the atv locus was fine-mapped to an approximately 5.0-kb interval on chromosome 7. A putative R3 MYB repressor was identified in this interval and is hereby designated as SlMYBATV...
November 25, 2017: Journal of Experimental Botany
https://www.readbyqxmd.com/read/29180962/tetradecyl-2-3-dihydroxybenzoate-improves-the-symptoms-of-diabetic-mice-by-modulation-of-insulin-and-adiponectin-signaling-pathways
#18
Lan Xiang, Jing Li, Yanhui Wang, Ruiqi Tang, Qian Wang, Qiaobei Wu, Jianhua Qi
Background: Tetradecyl 2,3-dihydroxybenzoate (ABG-001) derived from Chinese medicine, gentiana regescens Franch is a leading compound with NGF mimic effect, it can induce neurite outgrowth of PC12 cells via the IGF-1/PI3K/ERK signaling pathway. Thus, we inferred that this compound had anti-diabetic effect and used streptozocin (STZ)-induced diabetic mice to indicate it. Methods: ABG-001 was synthesized with 2,3-dihydroxybenzoic acid and tetradecyl alcohol under certain reaction conditions. STZ-induced diabetic mice were used to investigate anti-diabetic effect...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/29173817/adaptive-bone-remodeling-with-new-design-of-the-abg-stem-densitometric-study
#19
Jorge López-Subías, Juan J Panisello, Jesús M Mateo-Agudo, Marina Lillo-Adán, Antonio Herrera
To establish the pattern of bone remodeling caused by a cementless, anatomic implant, we intend to evaluate the changes in bone mineral density observed after surgery in the Gruen zones. A controlled, prospective study was carried out, in which a group of 37 patients with primary coxarthrosis were densitrometrically analyzed over the 1 year period following the implant of an ANATO stem (Stryker). The patient's healthy hip was taken as the control. Any differences in the remodeling pattern were compared according to age, body mass index, and implant size...
September 28, 2017: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/29172396/the-effect-of-endoscopic-tympanoplasty-on-cochlear-function
#20
Isa Kaya, Goksel Turhal, Arin Ozturk, Sercan Gode, Cem Bilgen, Tayfun Kirazli
Objectives: The aim of this prospective clinical study was to measure the audiologic outcomes of the patients that underwent endoscopic transcanal cartilage tympanoplasty, and to investigate the effects on cochlear function. Methods: Thirty-three patients (33 ears) who were diagnosed with noncomplicated chronic otitis media and underwent endoscopic transcanal cartilage tympanoplasty technique were included. Pre- and postoperative first month distortion product otoacoustic emission (DPOAE) signal-to-noise ratio (SNR), bone conduction hearing levels and air bone gap (ABG) values were measured and total endoscope usage time was noted...
November 28, 2017: Clinical and Experimental Otorhinolaryngology
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