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Heath D White, Alfredo Vazquez-Sandoval, Pedro F Quiroga, Juhee Song, Shirley F Jones, Alejandro C Arroliga
Acid-base status is frequently assessed in severe sepsis and septic shock. Venous blood gas sampling is proposed as a less-invasive modality but lacks evidence within this population. The objective of this study was to evaluate the correlation and agreement between arterial blood gas (ABG), peripheral venous blood gas (pVBG), and central venous blood gas (cVBG) in severe sepsis and septic shock. We conducted a prospective, observational cohort study in subjects admitted to the medical intensive care unit. Simultaneous blood gas samples, including ABG, pVBG, and cVBG, were analyzed for correlation and agreement...
July 2018: Proceedings of the Baylor University Medical Center
Foula Vassilara, Aikaterini Spyridaki, George Pothitos, Athanassia Deliveliotou, Antonios Papadopoulos
Human coronavirus 229E (HCoV-229E) is one of the first coronavirus strains being described. It is linked to common cold symptoms in healthy adults. Younger children and the elderly are considered vulnerable to developing lower respiratory tract infections (LRTIs). In particular, immunocompromised patients have been reported with severe and life-threatening LRTIs attributed to HCoV-229E. We report for the first time a case of LRTI and acute respiratory distress syndrome developed in a healthy adult with no comorbidities and HCoV-229E strain identified as the only causative agent...
2018: Case Reports in Infectious Diseases
Michael C Tanner, Raban Heller, Fabian Westhauser, Matthias Miska, Thomas Ferbert, Christian Fischer, Simone Gantz, Gerhard Schmidmaier, Patrick Haubruck
BACKGROUND: Treatment of non-union remains challenging and often necessitates augmentation of the resulting defect with an autologous bone graft (ABG). ABG is limited in quantity and its harvesting incurs an additional surgical intervention leaving the risk for associated complications and morbidities. Therefore, artificial bone graft substitutes that might replace autologous bone are needed. S53P4-type bioactive glass (BaG) is a promising material which might be used as bone graft substitute due to its osteostimulative, conductive and antimicrobial properties...
May 30, 2018: Trials
Y Han, J Chen, B Yue, Y Chen, D J Zha, J H Qiu
Objective: To analyze the clinical effect of 54 cases with chronic otitis media prepared for staging tympanoplasty and 19 cases finished staging ossicular reconstruction surgery, evaluate the advantages of different surgery technique. Method: Fifty-four cases with chronic otitis media were planned for staging tympanoplasty surgery and had been received the first stage surgery. Silicagel plates were placed in the tympanic cavity in order to prevent adhesions. Among them, 19 cases had received the second stage ossicular reconstruction, including 10 cases with TORPs and 9 cases with PORPs...
August 20, 2017: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
W Xiong, L E Wang, Y Liu, Z Peng, J Xie, S S Gong
Objective: To observe the clinical effect on the treatment of intractable tympanitis with reconstruction of external auditory canal wall. Method: Five cases underwent radical removel of residual lesion and reconsruction of external auditory posterior canal wall using hydroxyapatite ceramic wall with transferred pedicle temporalis fascia covering on it were analyzed. The implement of ossicular chain reconstruction depends on the probing for tympanic cavity intraoperatively. Periodic review were conducted in the 1st, 3rd, 6th, 12th month after surgery...
August 20, 2017: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
K Zhang, F R Ma, W M Song, T Pan, J Ke, Y Xin, S X Zhang, L Y Tao
Objective: To investigate the bone conduction (BC) in tympanosclerosis patients and its changes after surgery for tympanosclerosis, as well as its possible causes. Method: Retrospectively analyzed 30 cases of tympanosclerosis patients. Result: Before surgery, the average BC of the operated ear was (21.06±8.88) dBHL, the average BC of the healthy side was (16.78±8.97) dBHL, the difference had a statistical significance ( t = 3.072, P < 0.01). The BC threshold, air conduction (AC) and ABG were significantly lower after operation...
August 20, 2017: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
H L Li, Z F Zhang, T L Ren, M X Xie, W Q Wang
Objective: The aim of this study is to explore the feasibility and clinical effect of tympanoplasty combined with ventilation tube insertion in otitis media. Method: Retrospective analysis of 35 patients with eustachian tube obstruction or tympanic adhesions for tympanoplasty combined with ventil ation tube insertion in otitis media in EENT Hospital of Fudan University from April 2008 to December 2010. Preoperative routine hearing tests and temporal bone CT examination. Completely remove of lesions at the same time and as much as possible to protect the integrity of the tympanic wall mucosa during operation...
August 5, 2017: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
Y Gao, H N Luo, Q Zhang, Y Zhang, Y Cheng, B T Wang, J Hu, M Xu
Objective: The purpose of this study is to investigate the correlation of hearing and tinnitus improvement levels in chronic otitis media (COM) patients after tympanoplasty. Method: Thirty-five cases with COM, accompanied with tinnitus on the affected side or undefined sides, were enrolled and accepted for tympanoplasty between May 2015 and Dec 2016. Audiologic evaluation by pure tone audiometry and assessment of Tinnitus Handicap Inventory scores were conducted in pre-operation and 3 months post-operation...
September 5, 2017: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
N Y Feng, Y Zhang, X L Shen, X H Yan, Y Zhou, R X Ma
Objective: Through comparing of simple underlay myringoplasty performed in active and inactive inflammatory stage of the chronic otitis media, to explore how the tympanic cavity inflammation affect the outcome of the myringoplasty. Method: Forty-six ears were enrolled in active inflammation group (group A, n =46), and 52 ears were enrolled in inactive inflammation group (group B, n =52). All the patients had received the simple underlay technique myringoplasty. The following-up with otoscope and auditory test had been done in post-operative 12 months...
April 2018: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
Jie Wu, Meichen Pan, Huizhen Ouyang, Zhili Yang, Qiaoxin Zhang, Yingmu Cai
Arterial blood gas (ABG) analysis is important for acutely ill patients and should be performed by qualified laboratorians. The existing manual verifications are tedious, time-consuming, and prone to send wrong reports. Autoverification uses computer-based rules to verify clinical laboratory test results without manual review. To date, no data are available on the use of autoverification for ABG analysis. All autoverification rules were established according to AUTO10-A. Additionally, the rules were established using retrospective patient data, and then validated by actual clinical samples in a "live" environment before go-live...
May 1, 2018: SLAS Technology
Sinem Gungor, Feyza Kargin, Ilim Irmak, Fulya Ciyiltepe, Eylem Acartürk Tunçay, Pinar Atagun Guney, Emine Aksoy, Birsen Ocakli, Nalan Adiguzel, Zuhal Karakurt
Background: Patients admitted to the intensive care unit (ICU) with acute respiratory failure (ARF) due to COPD have high mortality and morbidity. Acidosis has several harmful effects on hemodynamics and metabolism, and the current knowledge regarding the relationship between respiratory acidosis severity on the short- and long-term survival of COPD patients is limited. We hypothesized that COPD patients with severe acidosis would have a poorer short- and long-term prognosis compared with COPD patients with mild-to-moderate acidosis...
2018: International Journal of Chronic Obstructive Pulmonary Disease
Mona Ascha, Anirban Bhattacharyya, Jose A Ramos, Adriano R Tonelli
INTRODUCTION/PURPOSE: Peripheral capillary oxygen saturation (SpO2) is used as surrogate for arterial blood oxygen saturation. We studied the degree of discrepancy between SpO2 and arterial oxygen (SaO2) and identified parameters that may explain this difference. METHODS: We included patients who underwent cardiopulmonary exercise testing (CPET) at Cleveland Clinic. Pulse oximeters with forehead probes measured SpO2 and arterial blood gas (ABG) samples provided the SaO2 both at rest and peak exercise...
April 30, 2018: Medicine and Science in Sports and Exercise
Joydeep Majumder, Ramanlal C Patel, Sanjay Kotadiya, Priyanka Shah
Background: Administrative workers working in quieter environment workplace are considered unaffected by noise-induced hearing loss (NIHL). Aim: To create a baseline data of the administrative workers so as to monitor them with prospective years of exposure with the hypothesis that workers working in the administrative jobs may not be affected by NIHL. Settings and Design: The study was conducted among men and women administrative workers working in an office in Ahmedabad city, India...
January 2018: Indian Journal of Occupational and Environmental Medicine
Laura L Lambert, Melissa B Baldwin, Cruz Velasco Gonzalez, Gary R Lowe, J Randy Willis
BACKGROUND: Transcutaneous monitors are utilized to monitor a patient's respiratory status. Some patients have similar values when comparing transcutaneous carbon dioxide ( P tcCO2 ) values with blood gas analysis, whereas others show extreme variability. A retrospective review of data was performed to determine how accurately P tcCO2 correlated with CO2 values obtained by arterial blood gas (ABG) or capillary blood gas. METHODS: To determine whether P tcCO2 values correlated with ABG or capillary blood gas values, subjects' records were retrospectively reviewed...
May 8, 2018: Respiratory Care
Robert J Yawn, Matthew M Dedmon, Brendan P O'Connell, Frank W Virgin, Alejandro Rivas
OBJECTIVE: To evaluate the use of porcine small intestinal submucosal grafts for tympanic membrane repair. PATIENTS: Adult and pediatric patients with tympanic membrane perforations with and without chronic otitits media, and perforations after removal of cholesteatoma. INTERVENTION: Endoscopic or microscopic tympanic membrane repair using porcine small intestinal submucosal grafts (Biodesign). MAIN OUTCOME MEASURE(S): Perforation closure, bone and air pure-tone averages (PTA), air-bone gap (ABG), and word recognition scores (WRS) were recorded as outcome measures...
June 2018: Otology & Neurotology
Sang Ho Jun, Chang-Joo Park, Suk-Hyun Hwang, Youn Ki Lee, Cong Zhou, Hyon-Seok Jang, Jae-Jun Ryu
Background: This study was to evaluate the effect of bone graft procedure on the primary stability of implants installed in fresh sockets and assess the vertical alteration of peri-implant bone radiographically. Methods: Twenty-three implants were inserted in 18 patients immediately after tooth extraction. The horizontal gap between the implant and bony walls of the extraction socket was grafted with xenografts. The implant stability before and after graft procedure was measured by Osstell Mentor as implant stability quotient before bone graft (ISQ bbg) and implant stability quotient after bone graft (ISQ abg)...
December 2018: Maxillofacial Plastic and Reconstructive Surgery
Christian Fischer, Christian Reiner, Gerhard Schmidmaier, Julian Doll, Christopher Child, Paul Alfred Grützner, Bahram Biglari, Sonja Boxriker, Arash Moghaddam
Background: In this prospective safety study, we investigated if the characteristic cytokine expression during bone regeneration is manipulated by the local application of bone morphogenetic protein-7 (BMP-7) in non-union surgery. Therefore, the levels of insulin like growth factor 1 (IGF-1), platelet-derived growth factor AB (PDGF-AB) and transforming growth factor beta (TGF-β) were compared between patients with the gold standard use of autologous bone graft (ABG) and those with additional application of BMP-7 as part of the diamond concept...
2018: Therapeutics and Clinical Risk Management
Anna Alberti, Enric Figuerola, Guillermo Romero-Farina, Miquel Quer, Francisco Larrosa
OBJECTIVES: To assess the long-term effectiveness of stapedotomies performed on patients with otosclerosis and preoperative small air-bone gaps (ABGs). METHODS: Retrospective study comparing the 10-year postoperative hearing outcomes after primary stapedotomies in patients with small (≤20 dB) and large ABGs (> 20 dB). Ninety out of 175 stapedotomies (22 and 68 in the small and large ABG groups, respectively) were monitored with long-term follow-ups. RESULTS: Ten years after the operation, hearing measurements were similar for both groups, although a significant decline of bone conduction thresholds was evident (p = 0...
April 26, 2018: Audiology & Neuro-otology
Patrick Haubruck, Julian Ober, Raban Heller, Matthias Miska, Gerhard Schmidmaier, Michael C Tanner
BACKGROUND: Autologous bone grafting (ABG) remains the gold standard for augmentation of bone defects. The RIA system has become more prevalent, but evidence regarding risk management and complications remain scarce. This study presents the risk management and complications associated with RIA in the largest single-center case series to date. METHODS: All records, operative notes, lab data and radiographs of patients receiving a RIA procedure at Heidelberg´s University Hospital between 01/01/2010 and 31/12/2016 were reviewed...
2018: PloS One
Sohila Seifi, Alireza Khatony, Gholamreza Moradi, Alireza Abdi, Farid Najafi
Background: Heart surgery patients are more at risk of poor peripheral perfusion, and peripheral capillary oxygen saturation (SpO2) measurement is regular care for continuous analysis of blood oxygen saturation in these patients. With regard to controversial studies on accuracy of the current pulse oximetry probes and lack of data related to patients undergoing heart surgery, the present study was conducted to determine accuracy of pulse oximetry probes of finger, toe, forehead and earlobe in detection of oxygen saturation in patients admitted to intensive care units for coronary artery bypass surgery...
2018: BMC Nursing
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