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https://www.readbyqxmd.com/read/27911311/risk-factors-and-pathological-substrates-associated-with-agitation-aggression-in-alzheimer-s-disease-a-preliminary-study-using-nacc-data
#1
Simrin Sennik, Tom A Schweizer, Corinne E Fischer, David G Munoz
BACKGROUND: Neuropsychiatric symptoms are common manifestations of Alzheimer's disease (AD). A number of studies have targeted psychosis, i.e., hallucinations and delusions in AD, but few have assessed agitation/aggression in AD. OBJECTIVE: To investigate the risk factors and pathological substrates associated with presence [A(+)] and absence [A(-)] of agitation/aggression (A) in autopsy-confirmed AD. METHODS: Data was collected from the UDS data as of 2015 on the NACC database...
November 28, 2016: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/27911301/tau-platelets-correlate-with-regional-brain%C3%A2-atrophy-in-patients-with-alzheimer-s%C3%A2-disease
#2
Andrea Slachevsky, Leonardo Guzmán-Martínez, Carolina Delgado, Pablo Reyes, Gonzalo A Farías, Carlos Muñoz-Neira, Eduardo Bravo, Mauricio Farías, Patricia Flores, Cristian Garrido, James T Becker, Oscar L López, Ricardo B Maccioni
BACKGROUND: Intracellular neurofibrillary tangles are part of the core pathology of Alzheimer's disease (AD), which are mainly composed of hyperphosphorylated tau protein. OBJECTIVES: The purpose of this study is to determine whether high molecular weight (HMW) or low molecular weight (LMW) tau protein levels, as well as the ratio HMW/LMW, present in platelets correlates with brain magnetic resonance imaging (MRI) structural changes in normal and cognitively impaired subjects...
November 26, 2016: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/27900920/-sudden-loss-of-consciousness-during-labour
#3
L T van Genugten, L P Morssink, E L van der Kooi
This case describes a 36-year-old woman, gravida 4 para 2 at 41 weeks and 3 days gestation, who appeared unconscious during labour for 75 minutes. After excluding physical disorders, it transpired that she was having a conversion disorder. A patient with a decreased level of consciousness in childbirth must be assessed using the ABCDE method, positioned in left lateral tilt to prevent inferior vena cava compression. After stabilization of the vital functions and establishing the patient's history, physical examination and laboratory tests are components of the initial clinical assessment...
2016: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/27898443/environmental-factors-and-myopia-paradoxes-and-prospects-for-prevention
#4
Kathryn Ailsa Rose, Amanda Nicole French, Ian George Morgan
The prevalence of myopia in developed countries in East and Southeast Asia has increased to more than 80% in children completing schooling, whereas that of high myopia has increased to 10%-20%. This poses significant challenges for correction of refractive errors and the management of pathological high myopia. Prevention is therefore an important priority. Myopia is etiologically heterogeneous, with a low level of myopia of clearly genetic origins that appears without exposure to risk factors. The big increases have occurred in school myopia, driven by increasing educational pressures in combination with limited amounts of time spent outdoors...
November 2016: Asia-Pacific Journal of Ophthalmology
https://www.readbyqxmd.com/read/27893924/deciding-how-best-to-treat-cartilage-defects
#5
Lucy Oliver-Welsh, Justin W Griffin, Maximilian A Meyer, Matthew E Gitelis, Brian J Cole
The decision-making regarding and treatment of cartilage abnormalities requires a systematic approach. This article reviews the concepts and principles that guide the management of this complex problem. The precise incidence, demographics, and progression of cartilage lesions have not been clearly delineated. Pursuing a patient-centered approach that considers the available nonsurgical and surgical options remains the cornerstone of patient care. The importance of determining concomitant knee pathologies, the proper interpretation and implications of imaging findings, and an accurate determination of the intra-articular and subchondral findings represent the primary elements of the decision analysis...
January 0: Orthopedics
https://www.readbyqxmd.com/read/27885821/exploring-simulation-in-the-internal-medicine-clerkship
#6
Brian Kwan, Glory Bui, Paul Jain, Nilesh Shah, Derek Juang
BACKGROUND: Simulation-based medical education has been shown to produce substantial educational benefits; however, the integration and effectiveness of high-fidelity simulation within the internal medicine (IM) clerkship remains largely unexplored. Investigators sought to determine the effectiveness of simulation in improving student confidence in acute coronary syndrome (ACS) and the Advanced Cardiac Life Support (ACLS) curriculum. Secondary goals included examining student perceptions of the role of simulation in medical education...
November 25, 2016: Clinical Teacher
https://www.readbyqxmd.com/read/27885064/differential-effects-of-aging-on-motor-and-cognitive-functioning-in-multiple-sclerosis
#7
Shumita Roy, Seth Frndak, Allison S Drake, Lauren Irwin, Robert Zivadinov, Bianca Weinstock-Guttman, Ralph Hb Benedict
BACKGROUND: Multiple sclerosis (MS) patients are impaired in motor and cognitive performance, but the extent to which these deficits are magnified by aging is unknown. In one prior study, differences in cognitive processing speed between MS patients and healthy individuals were of similar magnitude across the lifespan. Here, we have improved on this work by expanding assessment to multiple cognitive domains and motor functioning. OBJECTIVE: To determine whether the degree of cognitive and motor dysfunction in MS is magnified with increasing age...
November 24, 2016: Multiple Sclerosis: Clinical and Laboratory Research
https://www.readbyqxmd.com/read/27882040/a-new-model-of-master-of-philosophy-in-physiological-sciences
#8
H R Ahmad, F M Arain, N A Khan
The objectives of Master of Philosophy (MPhil) in Physiological Sciences are: 1) to describe the new ways in which anatomy, biochemistry and physiology on one hand, and microbiology, pathology and pharmacology on other hand meet their functional requirements through multidisciplinary integrated concepts; 2) to elucidate relationships between cell biology, molecular biology and molecular genetics by connecting dots of how cell functions are driven by molecules and being controlled by genes. This forms the basis of cell, molecular and genetics [CMG] module upon which 7 multidisciplinary modules of Physiological Sciences follow; 3) these 24 credit hours provide the physiological basis for PhD studies as well as faculty development to enhance learning abilities of medical student; 4) the modules constitute Cardio- Respiratory Physiological Sciences, GI and Renal Physiological Sciences, Neurosciences, Endo-Reproductive Physiological Sciences...
September 2016: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/27881928/internet-use-and-addiction-among-medical-students-of-universiti-sultan-zainal-abidin-malaysia
#9
Mainul Haque, Nor Azlina A Rahman, Md Anwarul Azim Majumder, Seraj Zohurul Haque, Zubair M Kamal, Zakirul Islam, Atm Emdadul Haque, Nor Iza A Rahman, Ahmed Ghazi Alattraqchi
BACKGROUND: The use of Internet has now become indispensable, and the technology has revolutionized the medical education and practice worldwide. Currently, medical students and professionals have an enormous opportunity to keep them always updated with the exponential growth of knowledge because of potential progression of Internet throughout the world that enables them to become a lifelong learner. Internet addiction is a widespread phenomenon among students and academicians at universities in Malaysia...
2016: Psychology Research and Behavior Management
https://www.readbyqxmd.com/read/27880065/fluctuations-in-the-emotional-intelligence-of-therapy-students-during-clinical-placements-implication-for-educators-supervisors-and-students
#10
Nigel Gribble, Richard K Ladyshewsky, Richard Parsons
This study investigated the changes in emotional intelligence (EI) of occupational therapy, physiotherapy, and speech pathology students (therapy students). Clinical placements have multiple benefits including the development of interprofessional skills, enhancing practice skills and interpersonal skills. Higher EI competencies have been shown to have a positive impact on patient outcomes, teamwork skills, dealing with stress, and patient satisfaction. Data for this study were collected at two time points: before third-year therapy students commenced extended clinical placements (T1 with 261 students) and approximately 7 months later after students had completed one or more clinical placements (T2 with 109 students)...
November 23, 2016: Journal of Interprofessional Care
https://www.readbyqxmd.com/read/27879439/interpreting-and-integrating-clinical-and-anatomic-pathology-results-pulling-it-all-together
#11
Lila Ramaiah, Mary Jane Hinrichs, Elizabeth V Skuba, William O Iverson, Daniela Ennulat
The continuing education course on integrating clinical and anatomical pathology data was designed to communicate the importance of using a weight of evidence approach to interpret safety findings in toxicology studies. This approach is necessary, as neither clinical nor anatomic pathology data can be relied upon in isolation to fully understand the relationship between study findings and the test article. Basic principles for correlating anatomic pathology and clinical pathology findings and for integrating these with other study end points were reviewed...
November 13, 2016: Toxicologic Pathology
https://www.readbyqxmd.com/read/27872547/measuring-dental-students-preference-a-comparison-of-light-microscopy-and-virtual-microscopy-as-teaching-tools-in-oral-histology-and-pathology
#12
Ohoud Alotaibi, Dalal ALQahtani
OBJECTIVES: Light microscopy used to be the traditional modality of teaching histology and pathology disciplines. Recent advances and innovations in the information technology field have revolutionized the use of hard- and software in medical education. An example of such an innovation is the so-called virtual microscopy. Many schools have started to adopt virtual microscopy as a new method aimed at enhancing student learning. Nonetheless, few reports have described the experiences of introducing virtual microscopy in dental education...
October 2016: Saudi Dental Journal
https://www.readbyqxmd.com/read/27871434/neural-correlates-of-anxiety-symptoms-in-mild-parkinson-s-disease-a-prospective-longitudinal-voxel-based-morphometry-study
#13
Natalie Wee, Ming-Ching Wen, Nagaendran Kandiah, Russell J Chander, Aloysius Ng, Wing Lok Au, Louis C S Tan
BACKGROUND: Anxiety is prevalent in patients with Parkinson's disease (PD) and may affect patients' quality of life. Yet, little is known about the neural basis of anxiety in PD, and none have used a longitudinal design. METHODS: 73 patients with mild PD were recruited and followed up for 18months. A whole-brain analysis was first used to identify brain regions associated with anxiety symptoms, followed by a regional analysis focusing on a priori hypothesised regions at baseline...
December 15, 2016: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/27870808/description-and-results-of-a-comprehensive-care-protocol-for-overnight-stay-spine-surgery-in-adults
#14
Drew A Bednar
STUDY DESIGN: This is a prospective cohort study. OBJECTIVE: To define the probability of successful morning-after discharge after adult spine surgery achieved with a standard care protocol as applied to patients with a large variety of common degenerative spine disorders. SUMMARY OF BACKGROUND DATA: Qualifying criteria for ambulatory or overnight-stay adult spine surgery are not well defined in either the spine or anesthesia literature. Most reports simply go to ASA risk classification or surgical technique alternatives and do not present a clearly defined patient care and case management protocol...
November 18, 2016: Spine
https://www.readbyqxmd.com/read/27866245/the-impact-of-socioeconomic-status-on-perioperative-complications-and-oncologic-outcomes-in-patients-undergoing-radical-cystectomy
#15
David M Golombos, Padraic O'Malley, Patrick Lewicki, Daniel P Nguyen, Benjamin V Stone, Bashir Al Hussein Al Awamlh, Douglas S Scherr
PURPOSE: To examine if patients of lower socioeconomic status (SES) are at higher risk of perioperative complications and experience different oncologic outcomes after radical cystectomy (RC). METHODS: Retrospective review was performed on 383 consecutive non-metastatic patients who underwent definitive RC at a tertiary referral center. Along with clinical and pathologic parameters traditionally utilized for risk stratification, potential social determinants of health were estimated using US Census data...
November 19, 2016: World Journal of Urology
https://www.readbyqxmd.com/read/27865311/conservative-and-pharmacologic-treatments-for-the-diabetic-charcot-foot
#16
REVIEW
Nina L Petrova, Michael E Edmonds
Charcot neuroarthropathy is a disabling complication of diabetic neuropathy. Prolonged immobilization in a total contact cast (TCC) is among the main treatments. Education of health care professionals in the application of TCC together with well-conducted clinical trials are required to overcome its frequent underuse. There are no established pharmacologic therapies to treat this condition; however, there is an overwhelming need for a new therapeutic approach. Novel targeted drug delivery systems are required to prevent the pathologic bone and joint destruction of the Charcot neuroarthropathy and this may lead to an improved outcome in diabetic patients with this condition...
January 2017: Clinics in Podiatric Medicine and Surgery
https://www.readbyqxmd.com/read/27863700/the-journal-of-comparative-pathology-educational-trust-2016-awards
#17
EDITORIAL
M J Day
No abstract text is available yet for this article.
November 15, 2016: Journal of Comparative Pathology
https://www.readbyqxmd.com/read/27860316/prevalence-of-myopic-retinopathy-in-rural-central-india
#18
Jost B Jonas, Vinay Nangia, Rajesh Gupta, Krishna Bhojwani, Prabhat Nangia, Songhomitra Panda-Jonas
PURPOSE: The aim of this study was to determine the prevalence of myopic retinopathy (MR) in rural Central India. METHODS: The population-based Central India Eye and Medical Study included 4711 subjects (aged 30+ years). The participants underwent a detailed eye examination, including fundus photography. Myopic retinopathy was defined according to the Pathologic Myopia Study Group. RESULTS: Readable fundus photographs were available on 4561 (96...
November 17, 2016: Acta Ophthalmologica
https://www.readbyqxmd.com/read/27857888/the-triple-q-algorithm-a-practical-approach-to-the-identification-of-liver-topography
#19
Omar Bekdache, Ahmad Zarour, Ayman El-Menyar, Yassir Abdulrahman, Husham Abdelrahman, Mohammad Ellabib, Ruben Peralta, Hassan Al-Thani
The descriptive identification and interpretation of liver pathology continue to raise debate, especially for trainees and junior physicians. There is wide diversity in the description of liver segmentation with sometimes contradictory terminology between French and American literature. Attempts were made to create a unified nomenclature that simplifies the problem. We propose a simple approach to describe the location of liver pathology in different settings by referring to an algorithm based on three questions...
October 2016: International Journal of Applied and Basic Medical Research
https://www.readbyqxmd.com/read/27854266/using-technology-bioinformatics-and-health-informatics-approaches-to-improve-learning-experiences-in-optometry-education-research-and-practice
#20
REVIEW
Vivek K Gupta, Veer B Gupta
Rapid advances in ocular diagnostic approaches and emerging links of pathological changes in the eye with systemic disorders have widened the scope of optometry as the front line of eye health care. Expanding professional requirements stipulate that optometry students get a meticulous training in relevant information and communication technologies (ICT) and various bioinformatics and health informatics software to meet current and future challenges. Greater incorporation of ICT approaches in optometry education can facilitate increased student engagement in shared learning experiences and improve collaborative learning...
November 15, 2016: Healthcare (Basel, Switzerland)
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