keyword
MENU ▼
Read by QxMD icon Read
search

PEM

keyword
https://www.readbyqxmd.com/read/28102938/low-energy-catalytic-electrolysis-for-simultaneously-hydrogen-evolution-and-lignin-depolymerization
#1
Xu Du, Wei Liu, Zhe Zhang, Arie Mulyadi, Alex Brittain, Jian Gong, Yulin Deng
Hereby we present a novel proton exchange membrane (PEM) electrolysis process in which lignin was used as the hydrogen source at anode for hydrogen production. Either polyoxometalate (POM) or FeCl3 was used as the catalysts and charge transfer agents in anode. Over 90% Faraday efficiency was achieved. In a thermal insulation reactor, the heat energy can be maintained at a very low stage for continuous operation. Compared to the best alkaline water electrolysis reported in literature, the electrical energy consumption could be 40% lower with novel lignin electrolysis method...
January 19, 2017: ChemSusChem
https://www.readbyqxmd.com/read/28099369/the-cessation-of-anti-pd-1-antibodies-of-complete-responders-in-metastatic-melanoma
#2
Rahul Ladwa, Victoria Atkinson
The optimal duration of PD-1 antibodies for metastatic melanoma is unknown. In previous trials, there has been the potential to cease therapy if the patient achieves a complete response (CR). We aimed to assess the outcomes of patients who had ceased anti-PD-1 antibodies in this setting. A retrospective review was carried out of CR to PD-1-based therapy across two institutions. Patients were from the Pembrolizumab Named Patient Program (PEM NPP), Nivolumab monotherapy (NIVO), and reimbursed Pembrolizumab (r PEM)...
January 17, 2017: Melanoma Research
https://www.readbyqxmd.com/read/28086790/rna-sequencing-for-global-gene-expression-associated-with-muscle-growth-in-a-single-male-modern-broiler-line-compared-to-a-foundational-barred-plymouth-rock-chicken-line
#3
Byung-Whi Kong, Nicholas Hudson, Dongwon Seo, Seok Lee, Bhuwan Khatri, Kentu Lassiter, Devin Cook, Alissa Piekarski, Sami Dridi, Nicholas Anthony, Walter Bottje
BACKGROUND: Modern broiler chickens exhibit very rapid growth and high feed efficiency compared to unselected chicken breeds. The improved production efficiency in modern broiler chickens was achieved by the intensive genetic selection for meat production. This study was designed to investigate the genetic alterations accumulated in modern broiler breeder lines during selective breeding conducted over several decades. METHODS: To identify genes important in determining muscle growth and feed efficiency in broilers, RNA sequencing (RNAseq) was conducted with breast muscle in modern pedigree male (PeM) broilers (n = 6 per group), and with an unselected foundation broiler line (Barred Plymouth Rock; BPR)...
January 13, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28086760/education-of-pediatric-subspecialty-fellows-in-transport-medicine-a-national-survey
#4
Geoffrey E Mickells, Denise M Goodman, Ranna A Rozenfeld
BACKGROUND: The transport of critically ill patients to children's hospitals is essential to current practice. The AAP Section on Transport Medicine has raised concerns about future leadership in the field as trainees receive less exposure to transport medicine. This study identifies the priorities of pediatric subspecialty fellows, fellowship directors and nursing directors in transport medicine education. METHODS: Internet based surveys were distributed to fellows, fellowship directors and nursing directors of transport teams affiliated with ACGME-approved fellowships in Neonatal-Perinatal Medicine (NPM), Pediatric Critical Care Medicine (PCCM), and Pediatric Emergency Medicine (PEM)...
January 13, 2017: BMC Pediatrics
https://www.readbyqxmd.com/read/28075559/one-component-supramolecular-filament-hydrogels-as-theranostic-label-free-magnetic-resonance-imaging-agents
#5
Lye Lin Lock, Yuguo Li, Xinpei Mao, Hanwei Chen, Verena Staedtke, Renyuan Bai, Wang Ma, Ran Lin, Yi Li, Guanshu Liu, Honggang Cui
Gadolinium (Gd)-based compounds and materials are the most commonly used magnetic resonance imaging (MRI) contrast agents in the clinic; however, safety concerns associated with their toxicities in the free ionic form have promoted the development of new generations of metal-free contrast agents. Here we report a supramolecular strategy to convert an FDA-approved anticancer drug, Pemetrexed (Pem), to a molecular hydrogelator with inherent chemical exchange saturation transfer (CEST) MRI signals. The rationally designed drug-peptide conjugate can spontaneously associate into filamentous assemblies under physiological conditions and consequently form theranostic supramolecular hydrogels for injectable delivery...
January 11, 2017: ACS Nano
https://www.readbyqxmd.com/read/28072617/evaluation-of-the-response-to-breast-cancer-neoadjuvant-chemotherapy-using-18f-fdg-positron-emission-mammography-compared-with-whole-body-18f-fdg-pet-a-prospective-observational-study
#6
Mutsumi Noritake, Kazutaka Narui, Tomohiro Kaneta, Sadatoshi Sugae, Kentaro Sakamaki, Tomio Inoue, Takashi Ishikawa
PURPOSE: The aim of this study was to assess therapeutic response to breast cancer neoadjuvant chemotherapy (NAC) by F-FDG positron emission mammography (PEM) compared with that to whole-body F-FDG PET (WBPET). METHODS: Twenty patients underwent WBPET and PEM 3 times: the first time was before NAC, the second time was after 2 courses of NAC, and the third time was after all courses of NAC. A pathological complete response (pCR) was defined as no evidence of residual invasive cancer with or without ductal carcinoma in situ...
January 9, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28069646/snapshot-profiling-of-anti-leishmanial-potency-of-lead-compounds-and-drug-candidates-against-intracellular-l-donovani-amastigotes-with-focus-on-human-derived-host-cells
#7
Markella Koniordou, Stephen Patterson, Susan Wyllie, Karin Seifert
This study characterised in vitro potencies of anti-leishmanial agents against intracellular Leishmania donovani amastigotes in primary human macrophages, obtained with or without CD14-positive monocyte enrichment, phorbol 12-myristate 13-acetate (PMA) differentiated THP-1 cells and mouse peritoneal exudate macrophages (PEMs). Host cell dependent potency was confirmed for pentavalent and trivalent antimony. Fexinidazole was inactive against intracellular amastigotes across the host cell panel. Fexinidazole sulfone, (R)-PA-824, (S)-PA-824 and VL-2098 displayed similar potency in all host cells tested...
January 9, 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/28060306/implementation-of-portable-emissions-measurement-systems-pems-for-the-real-driving-emissions-rde-regulation-in-europe
#8
Barouch Giechaskiel, Theodoros Vlachos, Francesco Riccobono, Fausto Forni, Rinaldo Colombo, Francois Montigny, Philippe Le-Lijour, Massimo Carriero, Pierre Bonnel, Martin Weiss
Vehicles are tested in controlled and relatively narrow laboratory conditions to determine their official emission values and reference fuel consumption. However, on the road, ambient and driving conditions can vary over a wide range, sometimes causing emissions to be higher than those measured in the laboratory. For this reason, the European Commission has developed a complementary Real-Driving Emissions (RDE) test procedure using the Portable Emissions Measurement Systems (PEMS) to verify gaseous pollutant and particle number emissions during a wide range of normal operating conditions on the road...
December 4, 2016: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28045649/cost-effectiveness-of-pemetrexed-in-combination-with-cisplatin-as-first-line-treatment-for-patients-with-advanced-non-squamous-non-small-cell-lung-cancer-in-spain
#9
Jonathan González García, Fernando Gutiérrez Nicolás, Gloria Julia Nazco Casariego, Cristina Valcárcel Nazco, Jose Norberto Batista López, Juana Oramas Rodríguez
INTRODUCTION: Lung cancer is the third most frequent neoplastic tumour in Spain, with around 27 000 new cases diagnosed per year; 80-95% of these are non-small-cell cancer (NSCLC), and the majority of cases are diagnosed in advanced stages of the disease, and for this reason it is one of the oncologic conditions with higher mortality rates (21.4% mean survival at 5 years). The main treatment regimens used for first-line treatment of NSCLC are: cisplatin/pemetrexed (cis/pem), cisplatin/gemcitabine/ bevacizumab (cis/gem/bev), and carboplatin/paclitaxel/ bevacizumab (carb/pac/bev)...
January 1, 2017: Farmacia Hospitalaria
https://www.readbyqxmd.com/read/28041826/interpretation-of-cerebrospinal-fluid-white-blood-cell-counts-in-young-infants-with-a-traumatic-lumbar-puncture
#10
Todd W Lyons, Andrea T Cruz, Stephen B Freedman, Mark I Neuman, Fran Balamuth, Rakesh D Mistry, Prashant Mahajan, Paul L Aronson, Joanna E Thomson, Christopher M Pruitt, Samir S Shah, Lise E Nigrovic
STUDY OBJECTIVE: We determine the optimal correction factor for cerebrospinal fluid WBC counts in infants with traumatic lumbar punctures. METHODS: We performed a secondary analysis of a retrospective cohort of infants aged 60 days or younger and with a traumatic lumbar puncture (cerebrospinal fluid RBC count ≥10,000 cells/mm(3)) at 20 participating centers. Cerebrospinal fluid pleocytosis was defined as a cerebrospinal fluid WBC count greater than or equal to 20 cells/mm(3) for infants aged 28 days or younger and greater than or equal to 10 cells/mm(3) for infants aged 29 to 60 days; bacterial meningitis was defined as growth of pathogenic bacteria from cerebrospinal fluid culture...
December 29, 2016: Annals of Emergency Medicine
https://www.readbyqxmd.com/read/28036307/an-overview-of-mosquitoes-and-emerging-arboviral-infections-in-the-zagreb-area-croatia
#11
Ana Klobucar, Nikola Benic, Darko Krajcar, Mirjana Lana Kosanovic-Licina, Vanja Tesic, Enrih Merdic, Ivana Vrucina, Vladimir Savic, Ljubo Barbic, Vladimir Stevanovic, Iva Pem-Novosel, Tatjana Vilibic-Cavlek
Mosquito control in the Zagreb area has been conducted for many years, whereas the fauna has only been investigated in the last 20 years. So far 30 mosquito species have been detected in the city area. Culex pipiens form molestus is the dominant mosquito species in indoor breeding sites. In forested areas and areas exposed to flooding, the active period is early spring and the dominant species are Ochlerotatus sticticus, Ochlerotatus cantans, Ochlerotatus geniculatus and Aedes vexans. The eudominant mosquito species found in the artificial breeding sites are Culex pipiens and the Asian tiger mosquito, Aedes albopictus...
December 30, 2016: Journal of Infection in Developing Countries
https://www.readbyqxmd.com/read/28034560/does-the-new-european-driving-cycle-nedc-really-fail-to-capture-the-nox-emissions-of-diesel-cars-in-europe
#12
Bart Degraeuwe, Martin Weiss
Tests with Portable Emissions Measurement Systems (PEMS) have demonstrated that diesel cars emit several times more NOX on the road than during certification on the New European Driving Cycle (NEDC). Policy makers and scientists have attributed the discrepancy to the unrealistically low dynamics and the narrow temperature range of NEDC testing. Although widely accepted, this assumption was never been put under scientific scrutiny. Here, we demonstrate that the narrow NEDC test conditions explain only a small part of the elevated on-road NOX emissions of diesel cars...
December 26, 2016: Environmental Pollution
https://www.readbyqxmd.com/read/28032662/5-hydroxymethylcytosine-is-a-nuclear-biomarker-to-assess-biological-potential-in-histologically-ambiguous-heavily-pigmented-melanocytic-neoplasms
#13
Jonathan J Lee, Ricardo E Vilain, Scott R Granter, Nina R Hu, Scott C Bresler, Shuyun Xu, Alexander H Frank, Martin C Mihm, Robyn P M Saw, Christopher D Fletcher, Richard A Scolyer, George F Murphy, Christine G Lian
BACKGROUND: 5-hydroxymethylcytosine (5-hmC) is an epigenetic marker detectable through immunohistochemistry (IHC) that has been shown to distinguish benign nevi from melanoma with high sensitivity and specificity. The purpose of the study was to explore its diagnostic utility in a subset of histologically challenging, heavily pigmented cutaneous melanocytic neoplasms. METHODS: 5-hmC IHC was performed on 54 heavily pigmented melanocytic tumors. Semi-quantitative analysis of immunoreactivity was correlated with clinical, pathologic, and follow-up data...
December 29, 2016: Journal of Cutaneous Pathology
https://www.readbyqxmd.com/read/28032510/ruthenium-catalyzed-ammonia-borane-dehydrogenation-mechanism-and-utility
#14
Xingyue Zhang, Lisa Kam, Ryan Trerise, Travis J Williams
One of the greatest challenges in using H2 as a fuel source is finding a safe, efficient, and inexpensive method for its storage. Ammonia borane (AB) is a solid hydrogen storage material that has garnered attention for its high hydrogen weight density (19.6 wt %) and ease of handling and transport. Hydrogen release from ammonia borane is mediated by either hydrolysis, thus giving borate products that are difficult to rereduce, or direct dehydrogenation. Catalytic AB dehydrogenation has thus been a popular topic in recent years, motivated both by applications in hydrogen storage and main group synthetic chemistry...
December 29, 2016: Accounts of Chemical Research
https://www.readbyqxmd.com/read/28028363/c5a-c5ar-pathway-is-essential-for-up-regulating-sphk1-expression-through-p38-mapk-activation-in-acute-liver-failure
#15
Yan-Chang Lei, Chun-Lei Lu, Ling Chen, Ke Ge, Ling-Ling Yang, Wen Li, Yuan-Hua Wu
AIM: To investigate the role of the complement 5a (C5a)/C5a receptor (C5aR) pathway in the pathogenesis of acute liver failure (ALF) in a mouse model. METHODS: BALB/c mice were randomly assigned to different groups, and intraperitoneal injections of lipopolysaccharide (LPS)/D-galactosamine (D-GalN) (600 mg/kg and 10 μg/kg) were used to induce ALF. The Kaplan-Meier method was used for survival analysis. Serum alanine aminotransferase (ALT) levels, at different time points within a 1-wk period, were detected with a biochemistry analyzer...
December 14, 2016: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28024645/graphene-oxide-based-nanohybrid-proton-exchange-membranes-for-fuel-cell-applications-an-overview
#16
REVIEW
Ravi P Pandey, Geetanjali Shukla, Murli Manohar, Vinod K Shahi
In the context of many applications, such as polymer composites, energy-related materials, sensors, 'paper'-like materials, field-effect transistors (FET), and biomedical applications, chemically modified graphene was broadly studied during the last decade, due to its excellent electrical, mechanical, and thermal properties. The presence of reactive oxygen functional groups in the grapheme oxide (GO) responsible for chemical functionalization makes it a good candidate for diversified applications. The main objectives for developing a GO based nanohybrid proton exchange membrane (PEM) include: improved self-humidification (water retention ability), reduced fuel crossover (electro-osmotic drag), improved stabilities (mechanical, thermal, and chemical), enhanced proton conductivity, and processability for the preparation of membrane-electrode assembly...
December 15, 2016: Advances in Colloid and Interface Science
https://www.readbyqxmd.com/read/28004572/infusing-lubricant-onto-erasable-microstructured-surfaces-toward-guided-sliding-of-liquid-droplets
#17
Xia-Chao Chen, Ke-Feng Ren, Jing Wang, Wen-Xi Lei, Jian Ji
Introducing a lubricant layer onto surfaces has emerged as a novel strategy to address a wide range of interface-related challenges. Recent studies of lubricant-infused surfaces have extended beyond repelling liquids to manipulating the mobility of fluids. In this study, we report a design of slippery surfaces based on infusing lubricant onto a polyelectrolyte multilayer film whose surface microstructures can be erased rapidly under mild condition. Unlike other lubricant-infused surfaces, the liquid movements (e...
January 18, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28002652/biomimetic-calcium-phosphate-polyelectrolyte-multilayer-coatings-for-sequential-delivery-of-multiple-biological-factors
#18
E Jacobs, G Gronowicz, M Hurley, L T Kuhn
Combinations of growth factors synergistically enhance tissue regeneration, but typically require sequential, rather than co-delivery from biomaterials for maximum efficacy. Polyelectrolyte multilayer (PEM) coatings can deliver multiple factors without loss of activity; however, sequential delivery from PEM has been limited due to interlayer diffusion that results in co-delivery of the factors. This study shows that addition of a biomimetic calcium phosphate (bCaP) barrier layer to a PEM coating effectively prevents interlayer diffusion and enables sequential delivery of two different biomolecules via direct cell access...
December 21, 2016: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/27994905/dilated-cardiomyopathy-induced-by-chronic-starvation-and-selenium-deficiency
#19
Soham Dasgupta, Ashraf M Aly
Protein energy malnutrition (PEM) has been rarely documented as a cause of cardiovascular abnormalities, including dilated cardiomyopathy. Selenium is responsible for antioxidant defense mechanisms in cardiomyocytes, and its deficiency in the setting of PEM and disease related malnutrition (DRM) may lead to exacerbation of the dilated cardiomyopathy. We report a rare case of a fourteen-year-old boy who presented with symptoms of congestive heart failure due to DRM and PEM (secondary to chronic starvation) along with severe selenium deficiency...
2016: Case Reports in Pediatrics
https://www.readbyqxmd.com/read/27987824/synthesis-of-thiolated-polysaccharides-for-formation-of-polyelectrolyte-multilayers-with-improved-cellular-adhesion
#20
Pegah Esmaeilzadeh, Alexander Köwitsch, Frank Heyroth, Georg Schmidt, Steffen Fischer, Katja Richter, Thomas Groth
Intrinsic cross-linking is not only useful for increasing stability, but also for tailoring mechanical properties of polyelectrolyte multilayers (PEM) on implants and tissue engineering scaffolds. Here, a novel route for synthesizing thiolated chitosan (t-Chi) based on the application of 3,3'-dithiodipropionic acid was applied, while thiolated chondroitin sulfate (t-CS) was conjugated by 3,3'-dithiobis (propanoic hydrazide). Both products were subsequently reduced to obtain the free thiols. The thiol content, structural changes and degree of substitution were studied by UV-vis, FTIR, Raman and (1)H NMR spectroscopy, respectively...
February 10, 2017: Carbohydrate Polymers
keyword
keyword
29527
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"