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https://www.readbyqxmd.com/read/28632577/outcome-of-pediatric-forearm-fracture-reductions-performed-by-pediatric-emergency-medicine-providers-compared-with-reductions-performed-by-orthopedic-surgeons-a-retrospective-cohort-study
#1
Donna Milner, Ernest Krause, Karen Hamre, Andrew Flood
OBJECTIVE: The aim of this study was to describe the outcome differences between board-certified orthopedists and pediatric emergency medicine (PEM) physicians conducting forearm fracture reductions. METHODS: We performed an analysis of patients between 1 and 14 years of age who presented to the emergency department (ED) with a forearm fracture requiring reduction. Data collected included reducing provider (PEM or orthopedist) and prereduction, postreduction, and follow-up fracture angles and displacements of both radius and ulna...
June 20, 2017: Pediatric Emergency Care
https://www.readbyqxmd.com/read/28625637/a-randomized-phase-2-evaluation-of-the-chk1-inhibitor-ly2603618-administered-in-combination-with-pemetrexed-and-cisplatin-in-patients-with-advanced-nonsquamous-non-small-cell-lung-cancer
#2
Thomas Wehler, Michael Thomas, Christian Schumann, Joaquim Bosch-Barrera, Nuria Viñolas Segarra, Nicolas J Dickgreber, Klaus Dalhoff, Martin Sebastian, Jesus Corral Jaime, Miriam Alonso, Scott M Hynes, Ji Lin, Karla Hurt, Aimee Bence Lin, Emiliano Calvo, Luis Paz-Ares
This phase 2 portion of a phase 1/2 study examined the efficacy and safety of LY2603618, a selective checkpoint kinase 1 inhibitor, combined with pemetrexed and cisplatin (LY+Pem+Cis) in patients with advanced nonsquamous non-small cell lung cancer (NSCLC). This multicenter, randomized, controlled, open-label study (NCT01139775) enrolled patients with stage IV nonsquamous NSCLC and an Eastern Cooperative Oncology Group performance status ≤1. Patients were randomized (2:1) to LY+Pem+Cis or pemetrexed and cisplatin (Pem+Cis)...
June 2017: Lung Cancer: Journal of the International Association for the Study of Lung Cancer
https://www.readbyqxmd.com/read/28624289/the-effect-of-child-family-and-environmental-factors-on-the-participation-of-young-children-with-disabilities
#3
Erica Di Marino, Stephanie Tremblay, Mary Khetani, Dana Anaby
BACKGROUND: While participation is essential to a child's health and well-being, little is known about participation patterns of young children with disabilities. OBJECTIVE: This study described the participation of children with disabilities under age 6, and examined the extent to which the child's factors (i.e., age, complexity of child's condition), family factors (i.e., general family functioning, income) and environmental factors (i.e., environmental helpfulness) affect participation dimensions (frequency, involvement, desire for change) in three different settings: home, daycare/preschool and community...
June 1, 2017: Disability and Health Journal
https://www.readbyqxmd.com/read/28621516/proton-conductivity-of-proton-exchange-membrane-synergistically-promoted-by-different-functionalized-metal-organic-frameworks
#4
Zhuang Rao, Beibei Tang, Peiyi Wu
In this study, two functionalized metal-organic frameworks (MOFs), UiO-66-SO3H and UiO-66-NH2 were synthesized. Then, different composite proton exchange membranes (PEMs) were prepared by single doping and co-doping of these two MOFs, respectively. It was found that co-doping of these two MOFs with suitable sizes was more conducive to the proton conductivity enhancement of the composite PEM. Synergistic effect between these two MOFs made the formation of more consecutive hydration channels in the composite PEM...
June 16, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28611637/a-case-of-posterior-reversible-encephalopathy-syndrome-induced-by-cisplatin-pemetrexed-chemotherapy-for-lung-cancer
#5
Masashi Ishihara, Noriyuki Matsutani, Shuji Ota, Nobuhiko Seki
This report presents the case of a 60-year-old woman who was diagnosed with stage IV lung adenocarcinoma with asymptomatic brain metastases and commenced chemotherapy with cisplatin/pemetrexed (CDDP/Pem). She experienced tonic-clonic convulsions on day 9 of the first cycle, which were accompanied by increased blood pressure (173/69 mm Hg) and headache. Therefore, brain MRI was performed to check for stroke or progression of brain metastatic foci. T2-weighted, FLAIR, and ADC map images showed high-intensity areas in the subcortical region of the bilateral parieto-occipital lobes, leading to a diagnosis of posterior reversible encephalopathy syndrome (PRES)...
January 2017: Case Reports in Oncology
https://www.readbyqxmd.com/read/28607213/consensus-guidelines-on-evaluation-and-management-of-the-febrile-child-presenting-to-the-emergency-department-in-india
#6
Prashant Mahajan, Prerna Batra, Neha Thakur, Reena Patel, Narendra Rai, Nitin Trivedi, Bernhard Fassl, Binita Shah, Marie Lozon, Rockerfeller A Oteng, Abhijeet Saha, Dheeraj Shah, Sagar Galwankar
JUSTIFICATION: No country-specific, evidence-based, consensus approach for the emergency department (ED) evaluation and management of the febrile child exist in India. PROCESS: We held two consensus meetings, performed an exhaustive literature review, and held ongoing web-based based discussions to arrive at a formal consensus on the proposed evaluation and management algorithm. The first meeting was held in Delhi in October 2015, under the auspices of Pediatric Emergency Medicine (PEM) Section of Academic College of Emergency Experts in India (ACEE-INDIA); and the second meeting was conducted at Pune during Emergency Medical Pediatrics and Recent Trends (EMPART 2016) in March 2016...
June 4, 2017: Indian Pediatrics
https://www.readbyqxmd.com/read/28603794/post-exertional-malaise-in-patients-with-me-and-cfs-with-comorbid-fibromyalgia
#7
Stephanie L McManimen, Leonard A Jason
BACKGROUND: Myalgic encephalomyelitis (ME) and chronic fatigue syndrome (CFS) share some similar symptoms with fibromyalgia (FM). Prior research has found increased illness severity when patients have FM that is comorbid with ME and CFS. For example, post-exertional malaise (PEM) has been shown to be more severe in those with comorbid FM. However, PEM can be separated into two factors, Muscle and General PEM. It is unknown if the more severe PEM findings in comorbid FM are due to the Muscle or General PEM factor...
2017: SRL Neurol Neurosurg
https://www.readbyqxmd.com/read/28577366/accuracy-of-four-intraoral-scanners-in-oral-implantology-a-comparative-in-vitro-study
#8
Mario Imburgia, Silvia Logozzo, Uli Hauschild, Giovanni Veronesi, Carlo Mangano, Francesco Guido Mangano
BACKGROUND: Until now, only a few studies have compared the ability of different intraoral scanners (IOS) to capture high-quality impressions in patients with dental implants. Hence, the aim of this study was to compare the trueness and precision of four IOS in a partially edentulous model (PEM) with three implants and in a fully edentulous model (FEM) with six implants. METHODS: Two gypsum models were prepared with respectively three and six implant analogues, and polyether-ether-ketone cylinders screwed on...
June 2, 2017: BMC Oral Health
https://www.readbyqxmd.com/read/28566606/pulmonary-endometriosis-which-probably-occurred-through-hematogenous-metastasis-after-artificial-abortion
#9
Kazushi Fujimoto, Hajime Kasai, Masaki Suga, Toshihiko Sugiura, Jiro Terada, Hidemi Suzuki, Masayuki Oota, Ichiro Yoshino, Yukio Nakatani, Koichiro Tatsumi
Pulmonary endometriosis (PEM) is a rare disease characterized by the proliferation of ectopic endometrial tissue in the lungs, which presents as catamenial hemoptysis. A 20-year-old-woman was admitted for repeated hemoptysis. Chest CT revealed a ground-glass opacity that appeared consistently with her menstrual cycle. Our detailed inquiry revealed a history of artificial abortion, which was followed by the use of oral contraceptives and catamenial hemoptysis after the discontinuation of these medications. Surgical removal was performed and histopathological examinations confirmed PEM...
2017: Internal Medicine
https://www.readbyqxmd.com/read/28547877/comparative-study-of-osteogenic-activity-of-multilayers-made-of-synthetic-and-biogenic-polyelectrolytes
#10
Deepak Guduru, Marcus S Niepel, Cristina Gonzalez-Garcia, Manuel Salmeron-Sanchez, Thomas Groth
Polyelectrolyte multilayer (PEM) coatings on biomaterials are applied to tailor adhesion, growth, and function of cells on biomedical implants. Here, biogenic and synthetic polyelectrolytes (PEL) are used for layer-by-layer assembly to study the osteogenic activity of PEM with human osteosarcoma MG-63 cells in a comparative manner. Formation of PEM is achieved with biogenic PEL fibrinogen (FBG) and poly-l-lysine (PLL) as well as biotinylated chondroitin sulfate (BCS) and avidin (AVI), while poly(allylamine hydrochloride) (PAH) and polystyrene sulfonate (PSS) represent a fully synthetic PEM used as a reference system here...
May 26, 2017: Macromolecular Bioscience
https://www.readbyqxmd.com/read/28535030/sulfonated-holey-graphene-oxide-shgo-filled-sulfonated-poly-ether-ether-ketone-membrane-the-role-of-holes-in-the-shgo-in-improving-its-performance-as-proton-exchange-membrane-for-direct-methanol-fuel-cells
#11
Zhong-Jie Jiang, Zhongqing Jiang, Xiaoning Tian, Lijuan Luo, Meilin Liu
Sulfonated holey graphene oxides (SHGOs) have been synthesized by the etching of sulfonated graphene oxides with concentrated HNO3 under the assistance of ultrasonication. These SHGOs could be used as fillers for the sulfonated aromatic poly(ether ether ketone) (SPEEK) membrane. The obtained SHGO-incorporated SPEEK membrane has a uniform and dense structure, exhibiting higher performance as proton exchange membranes (PEMs), for instance, higher proton conductivity, lower activation energy for proton conduction, and comparable methanol permeability, as compared to Nafion 112...
June 5, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28526408/semi-retentive-cytoskeletal-fractionation-sercyf-a-novel-method-for-the-biochemical-analysis-of-the-organization-of-microtubule-and-actin-cytoskeleton-networks
#12
Yuta Sato, Yota Murakami, Masayuki Takahashi
A variety of biochemical fractionation methods are available for the quantification of cytoskeletal components. However, each method is designed to target only one cytoskeletal network, either the microtubule (MT) or actin cytoskeleton, and non-targeted cytoskeletal networks are ignored. Considering the importance of MT-actin crosstalk, the organization of both the targeted and non-targeted cytoskeletal networks must be retained intact during fractionation for the accurate analysis of cytoskeletal organization...
May 17, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/28522391/polysaccharides-from-ginseng-leaves-inhibit-tumor-metastasis-via-macrophage-and-nk-cell-activation
#13
Myoung-Sook Shin, Su-Hyun Hwang, Taek-Joon Yoon, Kwang-Soon Shin
In this study, we purified the polysaccharide fraction (GS-P) from the leaves of Panax ginseng C.A. Meyer and analyzed its monosaccharide composition and antitumor and antimetastatic activity in vitro and in vivo. GS-P is a 10.2kDa pectic polysaccharide consisting of 15 different monosaccharides. GS-P treatment significantly inhibited metastasis in mice, in a dose-dependent manner. GS-P was not cytotoxic to colon 26-M3.1 cells and increased mouse splenocyte proliferation. Secretion of tumor necrosis factor (TNF)-α and interleukin (IL)-12 was enhanced in the peritoneal exudate macrophages (PEMs) of GS-P-treated mice...
May 15, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28511138/neurodevelopment-for-the-first-three-years-following-prenatal-mobile-phone-use-radio-frequency-radiation-and-lead-exposure
#14
Kyung-Hwa Choi, Mina Ha, Eun-Hee Ha, Hyesook Park, Yangho Kim, Yun-Chul Hong, Ae-Kyoung Lee, Jong Hwa Kwon, Hyung-Do Choi, Nam Kim, Suejin Kim, Choonghee Park
BACKGROUND: Studies examining prenatal exposure to mobile phone use and its effect on child neurodevelopment show different results, according to child's developmental stages. OBJECTIVES: To examine neurodevelopment in children up to 36 months of age, following prenatal mobile phone use and radiofrequency radiation (RFR) exposure, in relation to prenatal lead exposure. METHODS: We analyzed 1198 mother-child pairs from a prospective cohort study (the Mothers and Children's Environmental Health Study)...
July 2017: Environmental Research
https://www.readbyqxmd.com/read/28499602/from-polyelectrolyte-complexes-to-polyelectrolyte-multilayers-electrostatic-assembly-nanostructure-dynamics-and-functional-properties
#15
Biswa P Das, Marina Tsianou
Polyelectrolyte complexes (PECs) are three-dimensional macromolecular structures formed by association of oppositely charged polyelectrolytes in solution. Polyelectrolyte multilayers (PEMs) can be considered a special case of PECs prepared by layer-by-layer (LbL) assembly that involves sequential deposition of molecular-thick polyelectrolyte layers with nanoscale control over the size, shape, composition and internal organization. Although many functional PEMs with novel physical and chemical characteristics have been developed, the current practical applications of PEMs are limited to those that require only a few bilayers and are relatively easy to prepare...
December 16, 2016: Advances in Colloid and Interface Science
https://www.readbyqxmd.com/read/28497993/personal-variation-in-preference-for-sweetness-effects-of-age-and-obesity
#16
Nuala Bobowski, Julie A Mennella
BACKGROUND: Use of nonnutritive sweeteners (NNSs), which provide sweet taste with few to no calories, has increased, but data on whether children's hedonic responses to NNSs differ from nutritive sugars or from adults' hedonic responses are limited. METHODS: Most preferred levels of sucrose and the NNS sucralose were determined via a forced-choice tracking procedure in 48 children, 7-14 years (mean = 10 years), and 34 adults. Each participant also rated the liking of these taste stimuli, as well as varying concentrations of aspartame on 3- and 5-point facial hedonic scales...
May 12, 2017: Childhood Obesity
https://www.readbyqxmd.com/read/28491851/pemetrexed-induced-acute-kidney-failure-following-irreversible-renal-damage-two-case-reports-and-literature-review
#17
Tito Zattera, Francesco Londrino, Matteo Trezzi, Roberto Palumbo, Antonio Granata, Paola Tatangelo, Valentina Corbani, Valeria Falqui, Nadia Chiappini, Lisa Mathiasen, Marco Cavallini, Davide Rolla
BACKGROUND: Pemetrexed (PEM) is a new-generation multitargeted antifolate agent with a demonstrated broad-spectrum activity in several types of human cancers, including non-small cell lung cancer (NSCLC) and mesothelioma. Major side effects include dose-limiting hematologic toxicities. PEM nephrotoxicity is well known; however, its frequency is considered to be low. CASE PRESENTATION: Here we report two cases of acute kidney injury (AKI) related to PEM administration (500 mg/m2) in patients with NSCLC...
March 2017: Journal of Nephropathology
https://www.readbyqxmd.com/read/28482189/the-princess-and-the-pea-effect-influence-of-the-first-layer-on-polyelectrolyte-multilayer-assembly-and-properties
#18
Xuejian Lyu, Amy M Peterson
In many applications of polyelectrolyte multilayers (PEMs), a base polycation layer is adsorbed to promote adhesion of the PEM to the substrate. In this report, the effect of the first polyelectrolyte adsorbed in a PEM was investigated by assembling PEMs with first layer polycations of different chemistries and molecular weights. In this study, quartz crystal microbalance with dissipation monitoring (QCM-D) was used to monitor the PEM assembly process. First layer choice affects the total mass accumulation of the PEM as well as the stoichiometry of the PEM, although linear growth was observed in all cases...
April 29, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28479881/a-systematic-review-of-factors-affecting-energy-intake-of-adolescent-girls
#19
Bibi Mushirah Jodhun, Dhandevi Pem, Rajesh Jeewon
BACKGROUND: Adolescence is considered a critical period marked by an increase in energy intake to meet the body's physiological needs especially during puberty. This study reviews existing literature and critically analyses factors associated with eating habits and energy intake of adolescent girls. METHODS: A comprehensive search was conducted to identify at least 200 peer reviewed articles which dealt with the factors affecting energy intake (EI) and eating habits of adolescent girls...
December 2016: African Health Sciences
https://www.readbyqxmd.com/read/28475989/development-of-a-novel-proton-exchange-membrane-free-integrated-mfc-system-with-electric-membrane-bioreactor-and-air-contact-oxidation-bed-for-efficient-and-energy-saving-wastewater-treatment
#20
Changfei Gao, Lifen Liu, Fenglin Yang
A novel combined system integrating MFC and electric membrane bioreactor (EMBR) was developed, in which a quartz sand chamber (QSC) was used, replacing expensive proton exchange membrane (PEM). An air contact oxidation bed (ACOB) and embedded trickling filter (TF) with filled volcano rock, was designed to increase dissolved oxygen (DO) in cathodic EMBR to save aeration cost. Membrane fouling in EMBR was successful inhibited/reduced by the generated bioelectricity of the system. The combined system demonstrated superior effluent quality in removing chemical oxygen demand (>97%) and ammonia nitrogen (>93%) during the stable operation, and the phosphorus removal was about 50%...
August 2017: Bioresource Technology
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